Device for extracting and detecting biological sample

Abstract

The utility model discloses a device for extracting and detecting a biological sample, which relates to the technical field of detection devices and comprises a sampling barrel, a sampling and wiping rod is inserted in the sampling barrel, a detection reagent is arranged in the sampling barrel, a mixing tube is fixed and connected in the sampling barrel in a penetrating manner, a piston is connected in the mixing tube in a sliding manner, and the piston is connected with the sampling barrel in a sliding manner. One end of the piston is fixedly connected with a connecting rod, and the bottom side of the mixing pipe is fixedly connected with a liquid inlet pipe in a penetrating manner; the connecting rod enables the piston to move up and down, when the piston moves upwards, a mixed solution of a detection reagent and a sample is extracted through the liquid inlet pipe to enter the mixing pipe, and the piston moves downwards to discharge the mixed solution of the detection reagent and the sample out of the mixing pipe through the liquid outlet pipe. Then the detection box is inserted into the insertion groove, so that a mixed solution of a detection reagent and a sample in the sampling barrel drips into the detection box through the fixed pipe, and the detection of the sample is completed.

Description

Technical Field

[0001] The utility model relates to the technical field of detection devices, in particular to a device for extracting and detecting biological samples. Background Art

[0002] Lateral flow test strips generally include a bottom card, on which a sample pad, a marker binding pad (also referred to as a marker pad, usually using glass fiber as a carrier), a test pad (usually using NC membrane as a carrier) and a water-absorbing pad (usually using water-absorbing materials such as filter paper) are adhered one on the bottom card in sequence from upstream to downstream. The marker pad includes a marker that can bind to the analyte, such as latex labeled with antigens or antibodies, colloidal gold, fluorescent microspheres, etc.

[0003] In the prior art, a Chinese patent discloses a biological sample detection device (authorization announcement number CN217739199U). This patented technology can reduce the burden on the operator through an anti-misinsertion structure (the operator does not need to carefully observe whether the position of the upper cover is correct), improve the operator's work efficiency, and improve the product's qualification rate.

[0004] However, the above application document does not have an extraction structure when testing biological samples, which makes sampling more troublesome and cannot quickly test biological samples. Therefore, a device for extracting and testing biological samples is provided to solve the problems raised in the above background technology. Utility Model Content

[0005] The purpose of the present invention is to provide a device for extracting and detecting biological samples to solve the problems raised in the above-mentioned background technology.

[0006] In order to achieve the above purpose, the utility model provides the following technical solutions:

[0007] A device for extracting and detecting biological samples comprises a sampling barrel, a swab rod is inserted into the interior of the sampling barrel, a detection reagent is arranged inside the sampling barrel, a mixing tube is fixed and connected to the interior of the sampling barrel, a piston is slidably connected to the interior of the mixing tube, a connecting rod is fixedly connected to one end of the piston, a liquid inlet pipe is fixed and connected to the bottom side of the mixing tube, a liquid outlet pipe is fixed and connected to one side of the mixing tube, the connecting rod passes through the mixing tube, a fixed tube is fixed and connected to the bottom side of the sampling barrel, a symmetrical plug-in sleeve is fixedly connected to the lower side of the sampling barrel, a connecting frame is slidably connected to the lower side of the plug-in sleeve, a plug-in slot is provided inside the connecting frame, and a detection box is plugged into the plug-in slot.

[0008] As a further solution of the present utility model: wherein, an insertion interface is provided on the sampling cylinder, and a sleeve pipe is spirally connected inside the insertion interface, and the sleeve pipe is sleeved on the swab stick.

[0009] As a further solution of the present utility model: wherein, a plurality of elastic sheets are fixedly connected inside the fixed tube, and the elastic sheets are arranged in a conical shape.

[0010] As a further solution of the present utility model: wherein, springs are sleeved on both sides of the connection frame, and an insertion tube is fixedly and penetratingly connected in the middle of the connection frame, and the insertion tube and the fixed tube are mating components.

[0011] As a further solution of the present utility model: wherein, a test strip is arranged inside the test box, the test strip includes a collection paper and a display paper, and a display opening with the same specification size as the collection paper and the display paper is provided on the test box.

[0012] As a further solution of the present utility model: wherein, a water-absorbing paper is fixedly connected to the lower sides of the collection paper and the display paper, and a waterproof board is installed on the bottom side of the water-absorbing paper.

[0013] As a further solution of the present utility model: wherein, both the liquid inlet pipe and the liquid outlet pipe are one-way conduction pipes.

[0014] Compared with the prior art, the beneficial effects of the present utility model are:

[0015] Insert the sampling end of the swab stick into the inside of the sampling cylinder to mix the sample at the sampling end with the detection reagent inside the sampling cylinder, and then move the connecting rod up and down. The piston moves up and down through the connecting rod. When the piston moves up, the mixed liquid of the detection reagent and the sample is drawn into the mixing tube through the liquid inlet pipe, and when the piston moves down, the mixed liquid of the detection reagent and the sample is discharged from the mixing tube through the liquid outlet pipe. This method accelerates the mixing of the detection reagent and the sample, making the mixing of the detection reagent and the sample more uniform. Then insert the test box into the insertion slot, so that the mixed liquid of the detection reagent and the sample inside the sampling cylinder drips into the test box through the fixed tube to complete the detection of the sample; the above structure can facilitate the extraction and processing of biological samples through the provided swab stick and sampling cylinder, facilitate the rapid detection of biological samples, and improve the detection efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 It is a schematic diagram of the overall structure in the present utility model;

[0017] Figure 2 It is a schematic diagram of the connection frame structure in the present utility model;

[0018] Figure 3 It is a schematic cross-sectional view of the sampling cylinder structure in the present utility model;

[0019] Figure 4 This is a schematic structural diagram of the detection box in the present utility model;

[0020] Figure 5 This is a schematic structural diagram of the test strip in the present utility model;

[0021] The corresponding relationship between the reference numerals and component names in the figure is as follows:

[0022] 1. Sampling cylinder; 101. Insertion interface; 102. Sleeve pipe; 2. Sampling swab; 201. Mixing tube; 203. Connecting rod; 204. Piston; 205. Liquid inlet pipe; 206. Liquid outlet pipe; 207. Fixed pipe; 208. Elastic sheet; 3. Insertion sleeve; 301. Connection frame; 302. Spring; 303. Insertion pipe; 304. Insertion slot; 4. Detection box; 401. Test strip; 402. Absorbent paper; 403. Collection paper; 404. Display paper; 405. Waterproof board. Detailed implementation manners

[0023] Please refer to Figures 1 to 5 : A device for extracting and detecting biological samples, including a sampling cylinder 1, a sampling swab 2 is inserted into the interior of the sampling cylinder 1, a detection reagent is arranged inside the sampling cylinder 1, a mixing tube 201 is fixedly and through-connected inside the sampling cylinder 1, a piston 204 is slidably connected inside the mixing tube 201, one end of the piston 204 is fixedly connected to a connecting rod 203, a liquid inlet pipe 205 is fixedly and through-connected to the bottom side of the mixing tube 201, a liquid outlet pipe 206 is fixedly and through-connected to one side of the mixing tube 201, the connecting rod 203 penetrates through the mixing tube 201, a fixed pipe 207 is fixedly and through-connected to the bottom side of the sampling cylinder 1, two symmetric insertion sleeves 3 are fixedly connected to the lower side of the sampling cylinder 1, a connection frame 301 is slidably connected to the lower side of the insertion sleeve 3, an insertion slot 304 is formed inside the connection frame 301, and a detection box 4 is inserted into the insertion slot 304.

[0024] Among them, insert the sampling end of the sampling swab 2 into the interior of the sampling cylinder 1, so that the sample at the sampling end is mixed with the detection reagent inside the sampling cylinder 1, and then move the connecting rod 203 up and down. By means of the connecting rod 203, the piston 204 moves up and down. When the piston 204 moves upward, the mixed liquid of the detection reagent and the sample is drawn into the mixing tube 201 through the liquid inlet pipe 205. When the piston 204 moves downward, the mixed liquid of the detection reagent and the sample is discharged from the mixing tube 201 through the liquid outlet pipe 206. This method accelerates the mixing of the detection reagent and the sample, making the mixing of the detection reagent and the sample more uniform.

[0025] Preferably, an insertion interface 101 is formed on the sampling cylinder 1, a sleeve pipe 102 is spirally connected inside the insertion interface 101, and the sleeve pipe 102 is sleeved on the sampling swab 2.

[0026] Among them, the sampling swab 2 can be fixed in the sampling cylinder 1 by the arranged sleeve pipe 102 to prevent the sampling swab 2 from falling out of the sampling cylinder 1.

[0027] Preferably, a plurality of elastic sheets 208 are fixedly connected inside the fixing pipe 207, and the elastic sheets 208 are arranged in a conical shape.

[0028] Among them, the elastic sheet 208 arranged plays a role of sealing and plugging the fixing pipe 207, and can prevent the solution inside the sampling cylinder 1 from flowing out through the fixing pipe 207 when not in detection.

[0029] Preferably, springs 302 are sleeved on both sides of the connection frame 301, and an insertion pipe 303 is fixedly connected and penetrated through the middle of the connection frame 301. The insertion pipe 303 and the fixing pipe 207 are matching components.

[0030] Among them, when it is necessary to detect the mixed liquid inside the sampling cylinder 1, place the connection frame 301 on the desktop, press down the sampling cylinder 1, and the two ends of the connection frame 301 will slide into the inside of the insertion sleeve 3, so that the top end of the insertion pipe 303 is inserted into the inside of the fixing pipe 207, the top end of the insertion pipe 303 pushes open the elastic sheet 208, and the fixing pipe 207 and the insertion pipe 303 are penetrated, so that the mixed liquid drops into the inside of the detection box 4 through the insertion pipe 303.

[0031] Preferably, a test strip 401 is arranged inside the detection box 4. The test strip 401 includes a collection paper 403 and a display paper 404. A display opening of the same specification size as the collection paper 403 and the display paper 404 is opened on the detection box 4.

[0032] Among them, the mixed liquid will fall onto the collection paper 403 inside the detection box 4, and then the detection result can be displayed through the display paper 404.

[0033] Preferably, a water-absorbing paper 402 is fixedly connected to the lower sides of the collection paper 403 and the display paper 404, and a waterproof plate 405 is installed on the bottom side of the water-absorbing paper 402.

[0034] Among them, the water-absorbing paper 402 arranged can quickly transfer the mixed solution on the collection paper 403 to the display paper 404, and the arrangement of the water-absorbing paper 402 accelerates the absorption of the mixed liquid.

[0035] Preferably, both the liquid inlet pipe 205 and the liquid outlet pipe 206 are one-way conduction pipes.

[0036] Among them, the one-way conduction liquid inlet pipe 205 and the liquid outlet pipe 206 make the flow direction of the mixed liquid have a single direction, and can accelerate the mixing of the detection reagent and the sample.

[0037] Working principle: Insert the sampling end of the swab 2 into the interior of the sampling tube 1, so that the sample at the sampling end is mixed with the detection reagent inside the sampling tube 1. Then move the connecting rod 203 up and down. Through the connecting rod 203, the piston 204 moves up and down. When the piston 204 moves upward, the mixed liquid of the detection reagent and the sample is drawn into the mixing tube 201 through the liquid inlet pipe 205. When the piston 204 moves downward, the mixed liquid of the detection reagent and the sample is discharged from the mixing tube 201 through the liquid outlet pipe 206. This method accelerates the mixing of the detection reagent and the sample, making the mixing of the detection reagent and the sample more uniform. Then insert the detection box 4 into the insertion slot 304, so that the mixed liquid of the detection reagent and the sample inside the sampling tube 1 drips onto the inside of the detection box 4 through the fixed pipe 207. When it is necessary to detect the mixed liquid inside the sampling tube 1, place the connecting frame 301 on the desktop and press down the sampling tube 1. The two ends of the connecting frame 301 will slide into the interior of the insertion sleeve 3, so that the top end of the insertion pipe 303 is inserted into the interior of the fixed pipe 207, and the top end of the insertion pipe 303 pushes open the elastic piece 208, making the fixed pipe 207 communicate with the insertion pipe 303, so that the mixed liquid drips into the interior of the detection box 4 through the insertion pipe 303. The detection of the sample is completed.

[0038] The above is only the preferred specific embodiment of the present invention, but the protection scope of the present invention is not limited thereto. Any person skilled in the art within the technical scope disclosed by the present invention, according to the technical solution of the present invention and its inventive concept, makes equivalent substitutions or changes, and should be covered by the protection scope of the present invention.

Claims

1. An apparatus for extracting and detecting a biological sample, comprising a sampling cylinder (1), characterized in that, A swab stick (2) is inserted into the sampling cylinder (1). A detection reagent is provided inside the sampling cylinder (1). A mixing tube (201) is fixedly and through-connected inside the sampling cylinder (1). A piston (204) is slidably connected inside the mixing tube (201). One end of the piston (204) is fixedly connected to a connecting rod (203). A liquid inlet tube (205) is fixedly and through-connected to the bottom side of the mixing tube (201). A liquid outlet tube (206) is fixedly and through-connected to one side of the mixing tube (201). The connecting rod (203) penetrates through the mixing tube (201). A fixed tube (207) is fixedly and through-connected to the bottom side of the sampling cylinder (1). Symmetric plug-in sleeves (3) are fixedly connected to the lower side of the sampling cylinder (1). A connecting frame (301) is slidably connected to the lower side of the plug-in sleeve (3). A plug-in slot (304) is formed inside the connecting frame (301). A detection box (4) is inserted into the plug-in slot (304).

2. The device for extracting and detecting a biological sample according to claim 1, wherein An insertion opening (101) is formed in the sampling cylinder (1). A sleeve pipe (102) is screwed inside the insertion opening (101). The sleeve pipe (102) is sleeved on the swab stick (2).

3. The device for extracting and detecting a biological sample according to claim 1, wherein A plurality of elastic sheets (208) are fixedly connected inside the fixed tube (207). The elastic sheets (208) are arranged in a conical shape.

4. The device for extracting and detecting a biological sample according to claim 1, wherein Springs (302) are sleeved on both sides of the connecting frame (301). A connecting pipe (303) is fixedly and through-connected to the middle of the connecting frame (301). The connecting pipe (303) and the fixed tube (207) are mating components.

5. The device for extracting and detecting a biological sample according to claim 1, wherein, A test strip (401) is provided inside the detection box (4). The test strip (401) includes a collection paper (403) and a display paper (404). A display opening of the same specification size as the collection paper (403) and the display paper (404) is formed in the detection box (4).

6. The device for extracting and detecting a biological sample according to claim 5, wherein Absorbent papers (402) are fixedly connected to the lower sides of the collection paper (403) and the display paper (404). A waterproof board (405) is installed on the bottom side of the absorbent paper (402).

7. The device for extracting and detecting a biological sample according to claim 1, wherein, Both the liquid inlet tube (205) and the liquid outlet tube (206) are one-way conduction tubes.

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