Sulfonamide crystal separation device
By adopting the design of double-layer side walls and annular cooling plates in the crystallization kettle, combined with the use of stirring and scrapers, the problems of uneven cooling of the solution in the crystallization kettle and crystal adhesion are solved, and uniform cooling of the solution in the crystallization kettle and efficient crystallization are achieved.
Patent Information
- Application Number
- CN202422649333.9
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-10-31
- Publication Date
- 2025-10-14
- Estimated Expiration
- 2034-10-31
AI Technical Summary
The commonly used crystallization kettle has a large volume. The coolant on the outer wall of the crystallization kettle cools down the solution around it faster, but cools down the solution in the center of the crystallization kettle more slowly. In addition, as the crystallization proceeds, the crystals adhere to the inner wall of the crystallization kettle, blocking the heat transfer and affecting the crystallization efficiency.
The tank body is designed with double-layer side walls, and is equipped with a partition plate and an annular cooling plate. Combined with a stirring device and a scraper, the solution is evenly cooled through the tank side walls and the internal cooling plate, and crystals are scraped off to ensure smooth heat transfer.
The uniformity of the temperature reduction of the solution in the crystallization kettle is achieved, the crystallization efficiency is improved, the influence of crystal adhesion on heat transfer is avoided, and the reaction efficiency is improved.
Smart Images
Figure CN223429965U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of sulfanilamide processing, and specifically relates to a sulfanilamide crystallization separation device. Background Art
[0002] Sulfonamide, also known as p-aminobenzenesulfonamide, has a molecular formula of C6H8N2O2S and is a medicinally valuable organic compound. It is commonly used in the pharmaceutical industry as a primary raw material for the synthesis of sulfonamides. During the sulfonamide production process, a crystallizer is required to stir and cool the material to achieve crystallization.
[0003] The principle of the crystallization kettle is to use the supersaturation of the substance in the solution to make it supersaturated and form crystals. These crystals can be filtered and dried to obtain a solid product with higher purity. The crystallization kettle is equipped with a stirring device inside and a cooling pipe on the outer wall of the crystallization kettle. Stirring is carried out while cooling to ensure uniform crystallization.
[0004] However, since the commonly used crystallization kettle has a large volume, the coolant on the outer wall of the crystallization kettle cools down the solution around it faster, but cools down the solution in the center of the crystallization kettle slower. In addition, as crystallization proceeds, crystals adhere to the inner wall of the crystallization kettle, blocking heat transfer and affecting crystallization efficiency. Therefore, a sulfanilamide crystallization and separation device is provided. Utility Model Content
[0005] The utility model aims to provide a sulfanilamide crystallization and separation device to solve the problem that, due to the large volume of a commonly used crystallization kettle, the cooling liquid on the outer wall of the crystallization kettle cools the solution around it faster, but cools the solution in the center of the crystallization kettle slower, and as crystallization proceeds, the crystals adhere to the inner wall of the crystallization kettle, blocking heat transfer and affecting crystallization efficiency.
[0006] To achieve the above object, the present invention provides the following technical solution: a sulfanilamide crystallization and separation device, comprising:
[0007] The tank body has a double-layer side wall, and a plurality of evenly distributed partition plates are provided between the double-layer side walls of the tank body, so that the double-layer side walls of the tank body form a plurality of cooling chambers;
[0008] There are a plurality of annular cooling plates, which are sequentially sleeved inside the tank body, and the two ends of the bottom of each annular cooling plate are respectively connected to two opposite cooling cavities on the tank body;
[0009] A stirring device is provided on the top of the tank body and is used to stir the raw materials in the tank body;
[0010] There are several scrapers, all installed on the stirring device, for scraping off crystals on the inner wall of the tank and the side wall of the annular cooling plate.
[0011] Preferably, the annular cooling plate includes a heat exchange plate arranged in the tank body, an annular cavity is provided inside the heat exchange plate, a connecting channel is provided between the bottom of the annular cavity and the cooling cavity, and two heat exchange copper tubes arranged in a serpentine shape are provided between the two connecting channels and on the inner side of the annular cavity.
[0012] Preferably, the stirring device includes a driving motor arranged on the top of the tank body, the driving end of the driving motor extends into the tank body and is provided with a rotating frame, the lower end of the middle part of the rotating frame is provided with a first rotating rod extending into the inner annular cooling plate, and the side wall of the first rotating rod is provided with a number of evenly distributed first stirring rods.
[0013] Preferably, a plurality of annular gaps are formed between the side walls of the plurality of annular cooling plates and the inner wall of the tank body;
[0014] The stirring device also includes a second rotating rod rotatably installed at the lower end of the rotating frame and extending into the annular gap. The side wall of the second rotating rod is provided with a plurality of evenly distributed second stirring rods. The rotating shaft end of the second rotating rod is provided with a gear, and the top of the tank body is provided with an annular gear ring meshing with the gear.
[0015] Preferably, the scraper includes a plurality of first scrapers, a plurality of second scrapers and a third scraper;
[0016] The ends of the plurality of first stirring rods on the same side are commonly connected to one of the first scrapers;
[0017] The tops of the plurality of second scrapers are evenly distributed on the bottom surface of the rotating frame, and the lower ends of the second scrapers extend into the annular gap;
[0018] The plurality of third scrapers are all arranged at the bottom of the first rotating rod and are adapted to the bottom surface of the tank body.
[0019] Compared with the prior art, the present invention has the following beneficial effects: when in use, the present invention is a sulfonamide crystallization separation device. While the cooling liquid in the side wall of the tank cools the solution on the outside, the solution in the middle of the tank is cooled by a plurality of annular cooling plates arranged inside the tank, thereby ensuring uniform cooling of the solution in the tank.
[0020] The stirring device is used to stir the gap between several annular cooling plates and the inner wall of the tank, thereby improving the reaction efficiency of the solution, and the scraper is used to scrape off the crystals on the inner wall of the tank and the side wall of the annular cooling plate to avoid a large amount of crystal adhesion affecting heat transfer, thereby ensuring the efficiency of solution crystallization. BRIEF DESCRIPTION OF THE DRAWINGS
[0021] Figure 1 This is a schematic diagram of the main cross-sectional structure of the utility model;
[0022] Figure 2It is a schematic diagram of the top cross-sectional structure of the present utility model.
[0023] In the figure: 1. Tank body; 1-1. Partition plate; 2. Annular cooling plate; 2-1. Heat exchange plate; 2-2. Annular cavity; 2-3. Connecting channel; 2-4. Heat exchange copper tube; 3. Stirring device; 3-1. Drive motor; 3-2. Rotating frame; 3-3. First rotating rod; 3-4. First stirring rod; 3-5. Second rotating rod; 3-6. Second stirring rod; 3-7. Gear; 3-8. Annular gear ring; 4. Scraper; 4-1. First scraper; 4-2. Second scraper; 4-3. Third scraper. DETAILED DESCRIPTION
[0024] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.
[0025] See also Figure 1-2 The utility model provides a technical solution: a sulfanilamide crystallization separation device, comprising: a tank body 1 with a double-layer side wall, a plurality of evenly distributed partition plates 1-1 are arranged between the double-layer side walls of the tank body 1, so that the double-layer side walls of the tank body 1 form a plurality of cooling chambers, and the upper ends of the two opposite cooling chambers are respectively provided with a coolant inlet and a coolant outlet; a plurality of annular cooling plates 2 are provided, and are sequentially sleeved inside the tank body 1, the bottom ends of each annular cooling plate 2 are respectively connected to the two opposite cooling chambers on the tank body 1, the diameter of the inner annular cooling plate 2 is the same as the interval between the two annular cooling plates 2 and the interval between the outer cooling plate 2 and the inner wall of the tank body 1; a stirring device 3 is arranged on the top of the tank body 1, for stirring the tank body 1 The raw materials in the tank body 1 are stirred; a plurality of scrapers 4 are provided, all of which are installed on the stirring device 3 and are used to scrape off crystals on the inner wall of the tank body 1 and the side wall of the annular cooling plate 2. When in use, the cooling liquid in the side wall of the tank body 1 cools the solution on the outside, and the several annular cooling plates 2 set inside the tank body 1 cool the solution in the middle of the tank body 1, thereby ensuring the uniformity of cooling the solution in the tank body 1; the stirring device 3 is used to stir in the gap between the several annular cooling plates 2 and the inner wall of the tank body 1, thereby improving the reaction efficiency of the solution, and the scrapers 4 are used to scrape off crystals on the inner wall of the tank body 1 and the side wall of the annular cooling plate 2, thereby avoiding a large amount of crystal adhesion affecting heat transfer, thereby ensuring the efficiency of solution crystallization.
[0026] Specifically, the annular cooling plate 2 includes a heat exchange plate 2-1 arranged in the tank body 1, an annular cavity 2-2 is provided inside the heat exchange plate 2-1, a connecting channel 2-3 is provided between the bottom of the annular cavity 2-2 and the cooling cavity, and a heat-insulating layer is provided in the side wall of the connecting channel 2-3 to prevent crystallization caused by heat exchange between the solution and the connecting channel 2-3, thereby avoiding the problem of crystallization adhering to the connecting channel 2-3 and being difficult to scrape off. There are two connecting channels 2-3 and located on the inner side of the annular cavity 2-2. The heat exchange copper tubes 2-4 are arranged in a serpentine shape, and the two heat exchange copper tubes 2-4 are arranged opposite to each other in the annular cavity 2-2. The coolant in the cooling cavity in the tank body 1 enters the heat exchange copper tube 2-4 through the connecting channel 2-3 on one side and is discharged from the connecting channel 2-3 on the other side. When the coolant is in the heat exchange copper tube 2-4, the heat exchange copper tube 2-4 exchanges heat with the solution through the heat exchange plate 2-1, thereby realizing cooling of the solution in the middle of the tank body through the annular cooling plate 2, thereby ensuring uniform cooling of the solution in the tank body.
[0027] Specifically, the stirring device 3 includes a driving motor 3-1 arranged on the top of the tank body 1, the driving end of the driving motor 3-1 extends into the tank body 1 and is provided with a rotating frame 3-2, the rotating frame 3-2 is arranged as a cross structure, and the lower end of the middle part of the rotating frame 3-2 is provided with a first rotating rod 3-3 extending into the inner annular cooling plate 2, and a plurality of evenly distributed first stirring rods 3-4 are provided on the side wall of the first rotating rod 3-3. When in use, by starting the driving motor 3-1 to drive the rotating frame 3-2, the first rotating rod 3-3 and the plurality of first stirring rods 3-4 to rotate, the solution located inside the inner annular cooling plate 2 is stirred, thereby effectively improving the reaction efficiency of the solution.
[0028] Specifically, a plurality of annular gaps are formed between the side walls of the plurality of annular cooling plates 2 and the inner wall of the tank body 1, and the solution in the tank body 1 is divided into a plurality of cold zones by the plurality of annular gaps. This achieves cooling of the solution on the outside by the cooling liquid in the side walls of the tank body 1, while cooling of the solution in the middle of the tank body 1 by the plurality of annular cooling plates 2 set inside the tank body 1, thereby ensuring uniform cooling of the solution in the tank body; the stirring device 3 further includes a second rotating rod 3-5 rotatably mounted on the lower end of the rotating frame 3-2 and extending into the annular gap, and a plurality of evenly distributed second stirring rods 3-6 are provided on the side walls of the second rotating rod 3-5. , a gear 3-7 is provided at the rotating shaft end of the second rotating rod 3-5, and an annular gear ring 3-8 is provided on the top of the tank body 1 which is meshed with the gear 3-7. When in use, when the rotating frame 3-2 rotates, it drives the second rotating rods 3-5 and the second stirring rods 3-6 located on the second rotating rods 3-5 to rotate around the first rotating rod 3-3 in the annular gap. At the same time, the gear 3-7 on the second rotating rod 3-5 is meshed with the annular gear ring 3-8, and the gear 3-7 drives the second rotating rod 3-5 and the second stirring rod 3-6 to rotate, thereby realizing stirring of the solution located in the annular gap, thereby effectively improving the reaction efficiency of the solution.
[0029] Specifically, the scraper 4 includes a plurality of first scrapers 4-1, a plurality of second scrapers 4-2 and a third scraper 4-3; the ends of the plurality of first stirring rods 3-4 on the same side are commonly connected to a first scraper 4-1, and are in contact with the inner wall of the inner annular cooling plate 2 through the plurality of first scrapers 4-1, so as to scrape off the crystals on the inner wall of the inner annular cooling plate 2, so as to avoid a large amount of crystals adhering to the inner wall of the inner annular cooling plate 2 and affecting the heat transfer; the tops of the plurality of second scrapers 4-2 are evenly distributed on the bottom surface of the rotating frame 3-2, and the lower ends of the second scrapers 4-2 extend into the annular gap, and the second scraper 4-2 is provided with three scraping surfaces. The scraping surface of the second scraper 4-2 on the outside is used to scrape the upper end of the inner wall of the tank body 1 and the inner walls of the plurality of annular cooling plates 2 on the outside. The scraping surface of the scraper 4-2 on the inner side is used to scrape the outer wall contacts of all annular cooling plates 2, and the scraping surface of the second scraper 4-2 at the bottom is used to scrape the upper surface of the connecting channel 2-3 to prevent crystals from accumulating on the connecting channel 2-3, and to avoid a large amount of crystals adhering to affect the heat transfer. Several third scrapers 4-3 are arranged at the bottom of the first rotating rod 3-3 and are adapted to the bottom surface of the tank body 1. The bottom of the first rotating rod 3-3 has a connecting rod, and the third scraper 4-3 is arranged at the end of the connecting rod, and the third scraper 4-3 is adapted to the arc surface of the bottom of the tank body 1. When the first rotating rod 3-3 drives the third scraper 4-3 to rotate, the crystals adhering to the arc surface of the bottom of the tank body 1 are scraped off, thereby avoiding a large amount of crystals adhering to affect the heat transfer, thereby ensuring the efficiency of the solution crystallization.
[0030] Working principle: When the utility model is in operation, first, coolant is added to the coolant inlet of the cooling chamber on the tank body 1, and the coolant passes through the annular cooling plate 2 and enters the cooling chamber first, and is then discharged from the coolant outlet for circulating cooling. The stirring device 3 is started to stir the solution in the tank body 1. At the same time, the scraper 4 located on the stirring device 3 scrapes off the crystals to realize the operation of separating the sulfonamide crystals.
[0031] In the description of the present invention, unless otherwise expressly specified or limited, the terms "mounted," "connected," "connected," and "fixed" should be understood in a broad sense. For example, they may refer to fixed connection, detachable connection, or integration; mechanical connection or electrical connection; direct connection or indirect connection through an intermediate medium; and internal communication between two components or interaction between two components. Those skilled in the art will understand the specific meanings of the above terms in the present invention in specific circumstances.
[0032] The standard parts used in the present invention can all be purchased from the market, and special-shaped parts can be customized according to the description in the specification and the drawings. The specific connection methods of each part adopt conventional means such as mature bolts, rivets, welding, etc. in the existing technology. The machinery, parts and equipment all adopt conventional models in the existing technology, and the circuit connection adopts the conventional connection method in the existing technology, which will not be described in detail here.
[0033] While embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions, and variations may be made to these embodiments without departing from the principles and spirit of the invention, and that the scope of the invention is defined by the appended claims and their equivalents.
Claims
1. A sulfanilamide crystallization and separation device, characterized in that: include: The tank body (1) has a double-layer side wall, and a plurality of evenly distributed partition plates (1-1) are provided between the double-layer side walls of the tank body (1), so that the double-layer side walls of the tank body (1) form a plurality of cooling cavities; A plurality of annular cooling plates (2) are provided and are sequentially sleeved inside the tank body (1), with the bottom ends of each annular cooling plate (2) respectively communicating with two opposite cooling cavities on the tank body (1); A stirring device (3) is provided on the top of the tank body (1) and is used to stir the raw materials in the tank body (1); A plurality of scrapers (4) are provided, all of which are mounted on the stirring device (3) and are used to scrape off crystals on the inner wall of the tank body (1) and the side wall of the annular cooling plate (2).
2. A sulfanilamide crystallization and separation device according to claim 1, characterized in that: The annular cooling plate (2) comprises a heat exchange plate (2-1) arranged in a tank body (1); an annular cavity (2-2) is provided inside the heat exchange plate (2-1); a connecting channel (2-3) is provided between the bottom of the annular cavity (2-2) and the cooling cavity; and two heat exchange copper tubes (2-4) arranged in a serpentine shape are provided between the two connecting channels (2-3) and located on the inner side of the annular cavity (2-2).
3. A sulfanilamide crystallization separation device according to claim 1, characterized in that: The stirring device (3) includes a driving motor (3-1) arranged on the top of the tank body (1), a driving end of the driving motor (3-1) extends into the tank body (1) and is provided with a rotating frame (3-2), a first rotating rod (3-3) extending into the inner annular cooling plate (2) is provided at the lower end of the middle portion of the rotating frame (3-2), and a plurality of evenly distributed first stirring rods (3-4) are provided on the side wall of the first rotating rod (3-3).
4. A sulfanilamide crystallization and separation device according to claim 3, characterized in that: A plurality of annular gaps are formed between the side walls of the plurality of annular cooling plates (2) and the inner wall of the tank body (1); The stirring device (3) further comprises a second rotating rod (3-5) rotatably mounted on the lower end of the rotating frame (3-2) and extending into the annular gap; a side wall of the second rotating rod (3-5) is provided with a plurality of evenly distributed second stirring rods (3-6); a rotating shaft end of the second rotating rod (3-5) is provided with a gear (3-7); and the top of the tank body (1) is provided with an annular gear ring (3-8) meshingly connected with the gear (3-7).
5. A sulfanilamide crystallization separation device according to claim 4, characterized in that: The scraper (4) comprises a plurality of first scrapers (4-1), a plurality of second scrapers (4-2) and a third scraper (4-3); The ends of a plurality of the first stirring rods (3-4) located on the same side are commonly connected to one of the first scrapers (4-1); The tops of a plurality of the second scrapers (4-2) are evenly distributed on the bottom surface of the rotating frame (3-2), and the lower ends of the second scrapers (4-2) extend into the annular gap; The plurality of third scrapers (4-3) are all arranged at the bottom of the first rotating rod (3-3) and are adapted to the bottom surface of the tank body (1).