Colorimetric detection device for arsenic content in blood

Abstract

The utility model relates to the technical field of blood arsenic detection, and discloses a blood arsenic content colorimetric detection device which comprises a reaction bottle. According to the colorimetric detection device for the arsenic content in the blood, through the arrangement of the reaction bottle, the air supply pipe, the mercury bromide test paper and the colorimetric card, after blood is faded to be colorless and transparent from red by utilizing a form of proteolysis hemoglobin in the reaction bottle, tartaric acid is added into the reaction bottle; under the action of tartaric acid, colorless blood is combined with hydrogen in a reaction bottle gas production sheet to form gaseous arsenic hydride, the arsenic hydride is sprayed to mercury bromide test paper through a gas supply pipe, the mercury bromide test paper generates color spots, and the color spots are compared with the color on a colorimetric card, so that the concentration of the arsenic content in the blood is obtained. The arsenic detection kit is simple in structure, suitable for field detection and basic medical institutions, capable of detecting low-concentration arsenic and meeting clinical detection requirements, short in detection time and capable of obtaining detection results in a short time.

Description

TECHNICAL FIELD

[0001] The utility model relates to blood arsenic detection technical field especially relates to a blood arsenic content colorimetric detection device. BACKGROUND

[0002] Arsenic is a toxic element widely existing in nature. Excessive intake of arsenic by human body can cause a series of serious health problems, and long-term low-dose exposure may lead to skin lesions, cardiovascular diseases, nervous system damage and various chronic diseases such as cancer; and acute arsenic poisoning may endanger life rapidly. Since arsenic is widely distributed in the environment, it can enter the human body through various ways such as drinking water, food and air, so accurate detection of arsenic content in blood is of great importance for assessing arsenic exposure level, early detection of arsenic poisoning and formulating corresponding prevention and control measures.

[0003] At present, the main methods for blood arsenic detection include atomic fluorescence spectrometry, inductively coupled plasma mass spectrometry (ICP-MS) and the like. Although these methods have high sensitivity and accuracy, they usually require expensive instruments and equipment and complex operation procedures, which limits their application in on-site detection and primary medical institutions. SUMMARY

[0004] (I) Technical problem solved

[0005] The purpose of the utility model is to provide a blood arsenic content colorimetric detection device to solve the problem that expensive instruments and equipment and complex operation procedures are usually required, which limits their application in on-site detection and primary medical institutions.

[0006] (II) Technical scheme

[0007] In order to achieve the above purpose, the utility model is realized by the following technical scheme: a blood arsenic content colorimetric detection device, comprising a reaction bottle, a piston is connected to the top surface of the reaction bottle in a plug-in manner, a stirring assembly is arranged in the interior of the reaction bottle, a gas delivery pipe is connected to the surface of the piston in a sliding manner, a sealing cover is connected to one end of the gas delivery pipe in a sliding manner, a placement seat is connected to the bottom surface of the sealing cover in a sliding manner, a mercury bromide test paper is placed in the interior of the placement seat, an installation block is fixedly connected to the bottom surface of the placement seat, two groups of colorimetric cards are placed on the surface of the installation block, the stirring assembly comprises a rotating rod arranged in the interior of the reaction bottle, an electromagnet is magnetically connected to the bottom surface of the rotating rod, a controller is electrically connected to one end of the electromagnet through a power line, and the controller is electrically connected to one end of the electromagnet through a power line.

[0008] As a further scheme of the utility model, a storage tray is connected to the bottom surface of the reaction bottle in a lap joint manner, and a base is arranged on the outer side of the storage tray. Through the arrangement of the storage tray, the function of placing the reaction bottle is realized.

[0009] As a further scheme of the utility model, the bottom surface of the base is fixedly connected with four groups of supporting legs, the bottom surface of the four groups of supporting legs is fixedly connected with friction pads, through the setting of the friction pads, the effect of avoiding movement of the device during use is achieved.

[0010] As a further scheme of the utility model, the surface of the base is fixedly connected with a mounting seat, a supporting rod is threadedly connected in the mounting seat, through the setting of the supporting rod, the effect of supporting the funnel is achieved.

[0011] As a further scheme of the utility model, the outer side of the supporting rod is slidably connected with a sliding block, a threaded column is threadedly connected to one side of the sliding block, a rotating valve is fixedly connected to one side of the threaded column, through the setting of the rotating valve, the effect of driving the threaded column to move and fixing the sliding block is achieved.

[0012] As a further scheme of the utility model, one side of the sliding block is fixedly connected with a connecting rod, one end of the connecting rod is fixedly connected with a placing ring, through the setting of the placing ring, the effect of placing the funnel is achieved.

[0013] As a further scheme of the utility model, the top surface of the piston is slidably connected with a dropping tube, one end of the dropping tube is fixedly connected with a funnel, a flow control valve is arranged on one side of the dropping tube, through the setting of the flow control valve, the effect of controlling the dropping amount of liquid is achieved.

[0014] (Three) beneficial effects

[0015] The utility model provides a kind of blood arsenic content colorimetric detection device, with following beneficial effects:

[0016] 1、the blood arsenic content colorimetric detection device, by the setting of reaction bottle, gas pipe, mercuric bromide test paper and colorimetric card, after the form of hemoglobin is dissolved by protease in reaction bottle interior and blood is faded from red to colorless transparent, tartaric acid is added in reaction bottle interior, colorless blood combines with hydrogen in reaction bottle gas production piece into gaseous arsine under the action of tartaric acid, arsine is sprayed on mercuric bromide test paper by gas pipe, and color spot is generated on mercuric bromide test paper, compared with the color on colorimetric card, so as to know the concentration of blood arsenic content, this device not only does not need complex instrument and equipment, easy to operate, applicable to on-site detection and grass-roots medical institutions, low concentration of arsenic can also be detected, meet clinical detection demand, and detection time is short, detection result can be obtained in short time.

[0017] 2. The colorimetric detection device for blood arsenic content, through the setting of the stirring assembly, when tartaric acid is added dropwise in the colorless blood and reacts with hydrogen in the gas production sheet, the operator controls the strength of the electromagnet through the controller, so that the electromagnet generates a magnetic field, the rotating rod rotates under the action of the magnetic field, and the rotating rod stirs the inside of the reaction bottle when rotating, accelerates the reaction of the colorless blood and hydrogen, and thus accelerates the detection efficiency of the device. BRIEF DESCRIPTION OF DRAWINGS

[0018] Fig. 1 It is a whole structure schematic view of the utility model;

[0019] Fig. 2 It is a funnel structure schematic view of the utility model;

[0020] Fig. 3 It is a stirring assembly structure schematic view of the utility model;

[0021] Fig. 4 It is a colorimetric card structure schematic view of the utility model.

[0022] In the figure: 1, reaction bottle; 2, piston; 3, stirring assembly; 301, rotating rod; 302, electromagnet; 303, controller; 304, battery; 4, gas supply pipe; 5, sealing cover; 6, placing seat; 7, mercuric bromide test paper; 8, storage tray; 9, base; 10, supporting leg; 11, friction pad; 12, mounting seat; 13, supporting rod; 14, sliding block; 15, threaded column; 16, rotating valve; 17, connecting rod; 18, placing ring; 19, dropping tube; 20, funnel; 21, flow control valve; 22, mounting block; 23, colorimetric card. DETAILED DESCRIPTION

[0023] The technical solutions in the embodiments of the utility model will be described clearly and completely in combination with the drawings in the embodiments of the utility model. Based on the embodiments in the utility model, all other embodiments obtained by those skilled in the art without creative labor fall within the protection scope of the utility model.

[0024] Please refer to Figs. 1 to 4The utility model provides a technical scheme: a blood arsenic content colorimetric detection device, including reaction bottle 1, the top surface of reaction bottle 1 is inserted and is connected with piston 2, the inside of reaction bottle 1 is provided with stirring subassembly 3, piston 2's surface is connected with the gas delivery pipe 4 of sliding, one end of gas delivery pipe 4 is connected with the sealing cover 5 of sliding, the bottom surface of sealing cover 5 is connected with the placing seat 6 of sliding, the inside of placing seat 6 is placed with mercury bromide test paper 7, the bottom surface of placing seat 6 is fixedly connected with mounting block 22, the surface of mounting block 22 is placed with two groups of colorimetric card 23, stirring subassembly 3 includes the rotating stick 301 of setting in the inside of reaction bottle 1, the bottom surface of rotating stick 301 is magnetically connected with electromagnet 302, one end of electromagnet 302 is electrically connected with controller 303 through power line, one end of controller 303 is electrically connected with battery 304 through power line,

[0025] The bottom surface of reaction bottle 1 is lap jointed with the article placing tray 8, the outside of article placing tray 8 is provided with base 9, through the setting of article placing tray 8, the role of being used for placing reaction bottle 1 is played,

[0026] The bottom surface of base 9 is fixedly connected with four groups of support legs 10, the bottom surface of four groups of support legs 10 is fixedly connected with friction pad 11, through the setting of friction pad 11, the role of avoiding the movement of the device when being used is played,

[0027] The surface of base 9 is fixedly connected with mounting seat 12, the inside of mounting seat 12 is threadedly connected with support rod 13, through the setting of support rod 13, the role of supporting funnel 20 is played,

[0028] The outside of support rod 13 is slidably connected with sliding block 14, one side of sliding block 14 is threadedly connected with threaded column 15, one side of threaded column 15 is fixedly connected with rotating valve 16, through the setting of rotating valve 16, the role of driving threaded column 15 to move, so that sliding block 14 is fixed is played,

[0029] One side of sliding block 14 is fixedly connected with connecting rod 17, one end of connecting rod 17 is fixedly connected with placing ring 18, through the setting of placing ring 18, the role of placing funnel 20 is played,

[0030] The top surface of piston 2 is slidably connected with dropping tube 19, one end of dropping tube 19 is fixedly connected with funnel 20, one side of dropping tube 19 is provided with flow control valve 21, through the setting of flow control valve 21, the role of controlling liquid drop adding amount is played.

[0031] In the utility model, the working steps of the device are as follows:

[0032] The first step: after the blood is faded from red to colorless and transparent by the protease in the reaction bottle 1, tartaric acid is added in the reaction bottle 1, and the colorless blood combines with hydrogen in the reaction bottle 1 to form gaseous arsine under the action of tartaric acid, the arsine is sprayed on the mercuric bromide test paper 7 through the gas pipe 4, the mercuric bromide test paper 7 produces a color spot, and the color spot is compared with the color on the colorimetric card 23, so that the concentration of the arsenic content in the blood is obtained;

[0033] The second step: when the tartaric acid is added in the colorless blood and reacts with hydrogen in the gas production piece, the operator controls the strength of the electromagnet 302 through the controller 303, so that the electromagnet 302 generates a magnetic field, and the rotating rod 301 rotates under the action of the magnetic field, and the rotating rod 301 stirs the inside of the reaction bottle 1 when rotating, and accelerates the reaction of the colorless blood and hydrogen.

[0034] It should be noted that the device structure and the drawings of the utility model mainly describe the principle of the utility model, and the setting of the power mechanism, the power supply system and the control system of the device is not completely described in the technical principle of the design, and under the premise that the above-mentioned principle of the utility model is understood by the person skilled in the art, the specific power mechanism, power supply system and control system can be clearly known, and the control mode of the application file is automatically controlled by the controller, and the control circuit of the controller can be realized by simple programming of the person skilled in the art;

[0035] The standard parts used can be purchased from the market, and can be ordered according to the description and drawings, and the specific connection mode of each part adopts the conventional bolt, rivet, welding and other conventional means in the prior art, the mechanical parts and equipment adopt the conventional type in the prior art, and the components known by the person skilled in the art, the structure and principle are known by the person skilled in the art through technical manual or conventional experimental method.

[0036] Although the embodiments of the utility model have been shown and described, it can be understood by those skilled in the art that various changes, modifications, replacements and variations can be made to the embodiments without departing from the principle and spirit of the utility model, and the scope of the utility model is defined by the appended claims and their equivalents.

Claims

1. A colorimetric device for the determination of arsenic content in blood, comprising a reaction bottle (1), characterized in that: The top surface of the reaction bottle (1) is connected with a piston (2) through plug-in connection, the inside of the reaction bottle (1) is provided with a stirring assembly (3), the surface of the piston (2) is connected with a gas feeding pipe (4) through sliding connection, one end of the gas feeding pipe (4) is connected with a sealing cover (5) through sliding connection, the bottom surface of the sealing cover (5) is connected with a placing seat (6) through sliding connection, the inside of the placing seat (6) is placed with a mercury bromide test paper (7), the bottom surface of the placing seat (6) is fixedly connected with a mounting block (22), the surface of the mounting block (22) is placed with two groups of colorimetric cards (23), The stirring assembly (3) comprises a rotating rod (301) arranged in the inside of the reaction bottle (1), the bottom surface of the rotating rod (301) is connected with an electromagnet (302) through magnetic attraction, one end of the electromagnet (302) is electrically connected with a controller (303) through a power line, one end of the controller (303) is electrically connected with a storage battery (304) through a power line.

2. A colorimetric device for the detection of arsenic in blood as claimed in claim 1 wherein: The bottom surface of the reaction bottle (1) is connected with a storage tray (8) through lap joint, the outside of the storage tray (8) is provided with a base (9).

3. A colorimetric device for the detection of arsenic in blood according to claim 2, wherein: The bottom surface of the base (9) is fixedly connected with four groups of supporting legs (10), the bottom surface of each of the four groups of supporting legs (10) is fixedly connected with a friction pad (11).

4. A colorimetric device for the detection of arsenic in blood according to claim 3, wherein: The surface of the base (9) is fixedly connected with a mounting seat (12), the inside of the mounting seat (12) is threadedly connected with a supporting rod (13).

5. A colorimetric device for the detection of arsenic in blood according to claim 4, wherein: The outside of the supporting rod (13) is connected with a sliding block (14) through sliding connection, one side of the sliding block (14) is threadedly connected with a threaded column (15), one side of the threaded column (15) is fixedly connected with a rotating valve (16).

6. A colorimetric device for the detection of arsenic in blood according to claim 5, wherein: One side of the sliding block (14) is fixedly connected with a connecting rod (17), one end of the connecting rod (17) is fixedly connected with a placing ring (18).

7. The colorimetric device for detecting arsenic in blood according to claim 1, wherein: The top surface of the piston (2) is connected with a dropping tube (19) through sliding connection, one end of the dropping tube (19) is fixedly connected with a funnel (20), one side of the dropping tube (19) is provided with a flow control valve (21).

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