A device for suction filtration of floxuridine

Abstract

This application belongs to the technical field of pharmaceutical separation equipment, specifically relating to a fluorouridine filtration device. It includes a filtration cup, a filter media bottle positioned above the filtration cup for filling with fluorouridine, and a locking assembly. The inlet of the filtration cup corresponds to the outlet of the filter media bottle. A first docking platform is provided at the edge of the inlet, and a second docking platform corresponding to the first docking platform is provided at the edge of the outlet. This application achieves precise and rapid assembly of the filtration cup and filter media bottle by setting a first docking platform at the edge of the inlet and a second docking platform corresponding to the first docking platform at the edge of the outlet, and directly locking the two docking platforms using the locking assembly. The rigid constraint of the locking assembly automatically keeps the inlet / outlet coaxially aligned, avoiding the risk of poor sealing or component damage caused by traditional forceful pressing. Simultaneously, the platform-type docking structure requires only light force to lock or separate, significantly reducing the probability of material spillage during disassembly.

Description

Technical Field

[0001] This application belongs to the field of pharmaceutical separation equipment technology, specifically relating to a fluorouridine filtration device. Background Technology

[0002] Fluorouracil, a white crystalline powder, requires filtration during its preparation. Conventional apparatus uses a combination of a filtration flask and a filtration hopper. Filtration is achieved by placing filter paper above the hopper and creating negative pressure by drawing air out of the filtration flask. However, due to the large pore size of the filtration hopper, the filter paper is prone to tearing under negative pressure, leading to leakage of fluorouranidine into the filtration flask and product loss. Furthermore, to ensure a tight seal, the filtration hopper must be forcefully pressed into the filtration flask. This operation can easily cause component damage or disassembly difficulties. Forced separation can also result in material spillage due to excessive force, increasing the risk of experimental failure and significantly reducing work efficiency. Utility Model Content

[0003] In order to solve the problems of inconvenient connection between the filtration hopper and filtration bottle and the cracking of filter paper due to uneven filtration pressure in the prior art, this application provides a filtration device for fluorouridine.

[0004] This application is achieved through the following technical solution:

[0005] A fluorouridine filtration device includes a filtration cup, a filter media bottle disposed above the filtration cup for filling with fluorouridine, and a locking assembly. The inlet of the filtration cup corresponds to the outlet of the filter media bottle. A first docking platform is provided at the edge of the inlet, and a second docking platform corresponding to the first docking platform is provided at the edge of the outlet. The locking assembly is used to lock the first docking platform and the second docking platform to connect the filtration cup and the filter media bottle and to align the inlet and the outlet.

[0006] As described above, in a fluorouridine filtration device, the engaging assembly includes a first engaging member, a second engaging member hinged to the first engaging member, and a fastening mechanism for restricting or releasing the engagement of the first engaging member and the second engaging member. The first engaging member and the second engaging member engage to form a engaging groove into which the first docking platform and the second docking platform engage.

[0007] As described above, in a fluorouridine filtration device, the fastening mechanism includes a screw pivotally connected to the first locking member and a knob threadedly connected to the screw. Both the first and second locking members include corresponding engaging and abutting portions. The screw is pivotally connected to the abutting portion of the first locking member, and the knob abuts against the abutting portion of the second locking member to fasten the first and second locking members together.

[0008] In the fluorouridine filtration device described above, a sealing gasket is provided in the locking assembly between the first docking platform and the second docking platform.

[0009] The fluorouridine filtration device described above further includes a positioning protrusion and a positioning hole into which the positioning protrusion is inserted. The positioning protrusion is disposed on the first docking platform and the positioning hole is disposed on the second docking platform; or the positioning protrusion is disposed on the second docking platform and the positioning hole is disposed on the first docking platform, and the positioning protrusion is inserted into the positioning hole to align the outlet and the inlet.

[0010] In the fluorouridine filtration device described above, a filter element is provided inside the filter media bottle near the discharge port.

[0011] The fluorouridine filtration device described above uses a filter element made of quartz sand.

[0012] In the fluorouridine filtration device described above, filter paper is laid on the filter element inside the filter media bottle.

[0013] As described above, in a fluorouridine filtration device, the bottom of the filter bottle is a cone shape with an inner diameter that gradually decreases from top to bottom, and the filter element matches the contour of the inner wall of the bottom of the filter bottle.

[0014] The fluorouridine filtration device described above has an exhaust port extending outward and connected to an air supply pipe on the inner wall of the filtration cup.

[0015] Compared with the prior art, this application has the following advantages:

[0016] This application discloses a fluorouridine filtration device. By setting a first docking platform at the edge of the inlet and a second docking platform corresponding to the first docking platform at the edge of the outlet, and directly locking the two docking platforms using a locking assembly, the device achieves precise and rapid assembly of the filtration cup and the filter bottle. The rigid constraint of the locking assembly ensures that the inlet and outlet automatically maintain coaxial alignment, avoiding the risk of poor sealing or component damage caused by traditional forceful pressing. At the same time, the platform docking structure provides a stable force support point for the locking assembly, and locking or separation can be completed with only light force, significantly reducing the probability of material spillage during disassembly. Attached Figure Description

[0017] To more clearly illustrate the technical solutions in the embodiments of this application, the accompanying drawings used in the description of the embodiments will be briefly introduced below. Obviously, the accompanying drawings described below are only some embodiments of this application. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0018] Figure 1 This is a three-dimensional perspective view of an embodiment of this application;

[0019] Figure 2 yes Figure 1 Exploded view;

[0020] Figure 3 yes Figure 1 Top view;

[0021] Figure 4 yes Figure 3 Cross-sectional view at point AA;

[0022] Figure 5 This is a three-dimensional perspective view of the filter cup in the embodiments of this application;

[0023] Figure 6 This is a three-dimensional perspective view of the filter bottle in the embodiments of this application. Detailed Implementation

[0024] To make the technical problems solved by this application, the technical solutions, and the beneficial effects clearer, this application will be further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of this application and are not intended to limit this application.

[0025] Please see Figures 1 to 6 A fluorouridine filtration device includes a filtration cup 1, a filter media bottle 2 disposed above the filtration cup 1 for filling with fluorouridine, and a locking assembly 3. The inlet 11 of the filtration cup 1 corresponds to the outlet 21 of the filter media bottle 2. A first docking platform 12 is provided at the edge of the inlet 11, and a second docking platform 22 corresponding to the first docking platform 12 is provided at the edge of the outlet 21. The locking assembly 3 is used to lock the first docking platform 12 and the second docking platform 22 to connect the filtration cup 1 and the filter media bottle 2 and make the inlet 11 and the outlet 21 correspond.

[0026] This application discloses a fluorouridine filtration device. By setting a first docking platform at the edge of the inlet and a second docking platform corresponding to the first docking platform at the edge of the outlet, and directly locking the two docking platforms using a locking assembly, the device achieves precise and rapid assembly of the filtration cup and the filter bottle. The rigid constraint of the locking assembly ensures that the inlet and outlet automatically maintain coaxial alignment, avoiding the risk of poor sealing or component damage caused by traditional forceful pressing. At the same time, the platform docking structure provides a stable force support point for the locking assembly, and locking or separation can be completed with only light force, significantly reducing the probability of material spillage during disassembly.

[0027] Furthermore, as a preferred embodiment of this solution and not a limitation thereof, the engaging assembly 3 includes a first engaging member 31, a second engaging member 32 hinged to the first engaging member 31, and a fastening mechanism 33 for restricting or releasing the engagement of the first engaging member 31 and the second engaging member 32. The first engaging member 31 and the second engaging member 32 engage to form an engaging groove 34 for the first docking platform 12 and the second docking platform 22 to engage.

[0028] In this embodiment, a quick and stable connection between the filtration cup 1 and the filter bottle 2 is achieved through the hinge structure of the first locking member 31 and the second locking member 32, and the limiting or releasing function of the fastening mechanism 33. The working principle is as follows: When it is necessary to connect the filtration cup 1 and the filter bottle 2, the first docking platform 12 and the second docking platform 22 are aligned and engaged in the engaging groove 34 formed by the engagement of the first locking member 31 and the second locking member 32. The fastening mechanism 33, through the action of the screw 331 and the knob 332, firmly engages the first locking member 31 and the second locking member 32 together, thereby ensuring a tight connection between the filtration cup 1 and the filter bottle 2, and precise correspondence between the inlet 11 and the outlet 21. This avoids the problem of filter paper breakage or component damage caused by excessive pressure in traditional connection methods, improving the stability and reliability of the connection, and also facilitating quick disassembly and installation.

[0029] Furthermore, as a preferred embodiment of this solution and not a limitation thereof, the fastening mechanism 33 includes a screw 331 pivotally connected to the first locking member 31, and a knob 332 threadedly connected to the screw 331. The first locking member 31 and the second locking member 32 each include a corresponding engaging portion 311 and an abutting portion 312. The screw 331 is pivotally connected to the abutting portion 312 of the first locking member 31, and the knob 332 abuts against the abutting portion 312 of the second locking member 32 to fasten the first locking member 31 and the second locking member 32.

[0030] In this embodiment, a fastening mechanism consisting of a screw and a knob is used to achieve reliable locking and convenient adjustment of the connecting components of the filtration device. Its working principle is as follows: the screw is pivotally connected to the abutment portion of the first locking member. When the knob rotates along the screw, axial pressure is generated through its interaction with the abutment portion of the second locking member, causing the engaging portions of the two locking members to tightly engage, thereby firmly locking the first and second docking platforms within the engaging groove. This design not only ensures the stability and sealing of the connection, but also prevents accidental loosening during operation through the self-locking characteristic of the threaded drive, effectively solving the leakage problem caused by loose connections in traditional filtration devices, while significantly reducing the difficulty of disassembly.

[0031] Furthermore, as a preferred embodiment of this solution and not a limitation thereof, a sealing gasket 4 is provided in the engaging assembly 3 between the first docking platform 12 and the second docking platform 22.

[0032] In this embodiment, by setting a sealing gasket 4 between the first docking platform 12 and the second docking platform 22 within the locking assembly, the sealing performance and operational reliability of the filtration device are significantly improved. Its working principle is as follows: when the locking assembly 3 connects and fixes the filtration cup 1 and the filter bottle 2, the sealing gasket 4 is elastically deformed by the compression of the two docking platforms, thereby forming a uniform sealing ring at the connection interface. The sealing gasket 4 is compressed between the two, filling the tiny gaps at the connection point through its elastic deformation, thus preventing liquid or gas leakage, ensuring the smooth progress of the filtration process, improving filtration efficiency and quality, avoiding material loss and environmental pollution caused by leakage, and buffering the mechanical stress at the connection point to prevent component deformation caused by excessive tightening. This solves the common problem of reduced efficiency caused by poor sealing in traditional filtration devices, extends the device's service life, and improves the repeatability of experimental results.

[0033] Furthermore, as a preferred embodiment of this solution and not a limitation thereof, it also includes a positioning protrusion 5 and a positioning hole 6 into which the positioning protrusion 5 is inserted. The positioning protrusion 5 is disposed on the first docking platform 12 and the positioning hole 6 is disposed on the second docking platform 22; or the positioning protrusion 5 is disposed on the second docking platform 22 and the positioning hole 6 is disposed on the first docking platform 12, and the positioning protrusion 5 is inserted into the positioning hole 6 to align the discharge port 21 and the feed port 11.

[0034] In this embodiment, the feed inlet 11 of the filter cup 1 and the discharge outlet 21 of the filter bottle 2 are precisely aligned during connection, thereby ensuring that the material can flow smoothly from the filter bottle into the filter cup during the filtration process, avoiding material leakage or poor filtration due to misalignment of the interface. The positioning protrusion 5 and the positioning hole 6 are respectively set on the first docking platform 12 and the second docking platform 22. When the two are docked, the positioning protrusion 5 is inserted into the positioning hole 6, which can quickly and accurately guide the feed inlet 11 and the discharge outlet 21 to align, simplifying the installation steps, improving docking efficiency, and preventing tipping during installation, thus enhancing the stability of the connection.

[0035] Furthermore, as a preferred embodiment of this solution and not a limitation, a filter element 7 is provided inside the filter bottle 2 on the side near the discharge port 21.

[0036] In this embodiment, a filter element 7 is installed inside the filter media bottle 2 near the outlet 21, replacing the openings on a traditional filter funnel. Solid-liquid separation is achieved through the smaller, denser, and more uniform microporous structure on the filter element, ensuring smooth liquid flow while avoiding the problem of uneven stress and breakage of the filter paper caused by the larger openings and spacing in traditional filter funnels. This solves the product loss problem caused by filter media breakage, a common issue in traditional vacuum filtration devices.

[0037] Furthermore, as a preferred embodiment of this solution and not a limitation thereof, the filter element 7 is made of quartz sand.

[0038] In this embodiment, quartz sand, with its uniform particle distribution and stable chemical properties, forms a uniform pore structure during the filtration process. This ensures a uniform distribution of filtration pressure, preventing filter paper damage, and also resists the chemical corrosion of fluorouracil solutions. Furthermore, the high thermal stability of quartz sand makes it suitable for vacuum filtration operations under different temperature conditions. This design not only solves the problems of easy corrosion of traditional metal filter screens and the inability of polymer filter elements to withstand high temperatures, but also improves filtration efficiency by optimizing the fluid path.

[0039] Furthermore, as a preferred embodiment of this solution and not a limitation, filter paper is laid on the filter element 7 inside the filter bottle 2.

[0040] In this embodiment, by laying filter paper on the surface of the quartz sand filter element 7, multi-stage fine filtration of fluorouridine solution is achieved. The quartz sand filter element 7 serves as a supporting skeleton to provide uniform mechanical support and primary filtration, while the surface filter paper achieves final precision filtration. This composite filtration structure not only leverages the advantages of quartz sand in corrosion resistance and uniform pressure distribution, but also retains the high-precision filtration characteristics of filter paper. At the same time, the quartz sand layer can effectively buffer the filtration pressure and prevent the filter paper from being damaged due to excessive local pressure.

[0041] Furthermore, as a preferred embodiment of this solution and not a limitation thereof, the bottom of the filter bottle 2 is a conical shape with an inner diameter that gradually decreases from top to bottom, and the filter element 7 matches the contour of the inner wall of the bottom of the filter bottle 2.

[0042] In this embodiment, the conical structure naturally forms a gradually narrowing flow channel, allowing the filtration pressure to increase uniformly from top to bottom. This avoids the uneven filtration caused by the edge effect common in traditional cylindrical filter media bottles, and improves filtration efficiency through the gradually increasing filtration pressure. Simultaneously, the filter element 7, which fits perfectly with the bottle body, eliminates dead corners easily formed by traditional planar filter media, ensuring full utilization of the entire filtration area. This not only solves the problem of localized overload damage to the filter media caused by uneven pressure distribution in traditional devices, but also significantly improves filtration speed and product recovery rate through optimized flow channel design.

[0043] Furthermore, as a preferred embodiment of this solution and not a limitation thereof, the inner wall of the filter cup 1 is provided with an exhaust nozzle 8 that extends outward and is connected to an air supply pipe.

[0044] In this embodiment, during the filtration process, the air inside the filtration cup 1 is extracted through the air tube, creating a negative pressure inside the cup. Under atmospheric pressure, the filtrate passes through the filter element 7 and filter paper more quickly, while solid particles are trapped inside the filter media bottle 2, thereby achieving rapid separation.

[0045] The working principle of this embodiment is as follows:

[0046] This application discloses a fluorouridine filtration device. By setting a first docking platform at the edge of the inlet and a second docking platform corresponding to the first docking platform at the edge of the outlet, and directly locking the two docking platforms using a locking assembly, the device achieves precise and rapid assembly of the filtration cup and the filter bottle. The rigid constraint of the locking assembly ensures that the inlet and outlet automatically maintain coaxial alignment, avoiding the risk of poor sealing or component damage caused by traditional forceful pressing. At the same time, the platform docking structure provides a stable force support point for the locking assembly, and locking or separation can be completed with only light force, significantly reducing the probability of material spillage during disassembly.

[0047] The above are implementation methods provided in conjunction with specific content, and it is not intended that the specific implementation of this application is limited to these descriptions. Any methods or structures that are similar to those of this application, or any technical deductions or substitutions made based on the concept of this application, should be considered within the scope of protection of this application.

Claims

1. A device for the filtration of floxuridine, characterized in that, The filter includes a filtration cup (1), a filter media bottle (2) located above the filtration cup (1) and used for filling fluorouridine, and a locking assembly (3). The inlet (11) of the filtration cup (1) corresponds to the outlet (21) of the filter media bottle (2). A first docking platform (12) is provided at the edge of the inlet (11), and a second docking platform (22) corresponding to the first docking platform (12) is provided at the edge of the outlet (21). The locking assembly (3) is used to lock the first docking platform (12) and the second docking platform (22) to connect the filtration cup (1) and the filter media bottle (2) and make the inlet (11) and the outlet (21) correspond.

2. The apparatus for filtering of floxuridine according to claim 1, wherein, The engaging assembly (3) includes a first engaging member (31), a second engaging member (32) hinged to the first engaging member (31), and a fastening mechanism (33) for limiting or releasing the engagement of the first engaging member (31) and the second engaging member (32), wherein the first engaging member (31) and the second engaging member (32) form an engaging groove (34) into which the first docking platform (12) and the second docking platform (22) engage.

3. The sintering device of claim 2, wherein the sintering device is a device for sintering fluorouridine, characterized in that The fastening mechanism (33) includes a screw (331) pivotally connected to the first locking member (31) and a knob (332) threadedly connected to the screw (331). The first locking member (31) and the second locking member (32) each include a corresponding engaging portion (311) and an abutting portion (312). The screw (331) is pivotally connected to the abutting portion (312) of the first locking member (31), and the knob (332) abuts against the abutting portion (312) of the second locking member (32) to fasten the first locking member (31) and the second locking member (32).

4. The sintering device of floxuridine according to claim 1, characterized in that, The engaging assembly (3) is provided with a sealing gasket (4) located between the first docking platform (12) and the second docking platform (22).

5. The filtration apparatus for fluorouridine according to claim 1, characterized in that, It also includes a positioning protrusion (5) and a positioning hole (6) for inserting the positioning protrusion (5), the positioning protrusion (5) being disposed on the first docking platform (12) and the positioning hole (6) being disposed on the second docking platform (22); or the positioning protrusion (5) being disposed on the second docking platform (22) and the positioning hole (6) being disposed on the first docking platform (12), the positioning protrusion (5) being inserted into the positioning hole (6) to align the discharge port (21) and the feed port (11).

6. The filtration apparatus for fluorouridine according to claim 1, characterized in that, The filter element (7) is provided inside the filter bottle (2) on the side near the discharge port (21).

7. The filtration apparatus for fluorouridine according to claim 6, characterized in that, The filter element (7) is made of quartz sand.

8. The sintering device of claim 7, wherein the sintering device is a device for sintering fluorouridine. Filter paper is laid on the filter element (7) inside the filter bottle (2).

9. The sintering device of claim 6, wherein, The bottom of the filter bottle (2) is a cone shape with an inner diameter that gradually decreases from top to bottom, and the filter element (7) matches the inner wall contour of the bottom of the filter bottle (2).

10. The sintering device of floxuridine according to claim 1, characterized in that, The inner wall of the filter cup (1) is provided with an exhaust nozzle (8) that extends outward and is connected to an air supply pipe.

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