The invention discloses a vertical full-automatic capsule drying device. The vertical full-automatic capsule drying device comprises a box body, a rotating shaft, a drying barrel mounting clamping ring, a discharging plate, a drying barrel, a spiral guiding plate, a rotating shaft motor, a conveying belt, a feeding pipe, infrared device fixing plates, a fan, a discharging outlet, infrared generating devices, an exhaust fan, a connecting rod, an eccentric wheel, a motor, a hinge, a filter screen, a powerful negative pressure fan, a feeding inlet, a charging hole, a storage box, a negative pressure fan storage box, a negative pressure fan controlling device and a dust collector. According to the vertical full-automatic capsule drying device, the principle of infrared heating drying and the meshed drying barrel with the two ends open are adopted, and therefore the phenomena that capsules are deformed, melted, adhered and partially hardened due to uneven heating are effectively avoided; the dust collector is mounted on the feeding pipe, so that dust removing of the capsules is achieved while the capsules are dried.