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Preservation by Vaporization

Significant research is being done to develop and improve delivery mechanisms for biopharmaceuticals and vaccines, including pulmonary (inhalation), nasal, transdermal, and oral alternatives. Market projections indicate that the delivery of proteins and vaccines by inhalation and oral formulation has become and will continue to be increasingly important. These delivery mechanisms, to be effective, will require better stabilization of the biologicals so that they can maintain potency and effectiveness at ambient temperatures for extended periods of time. The novel Preservation by Vaporization (PBV) Technology described herein provides cost-effective and efficient industrial scale stabilization of proteins, viruses, bacteria, and other sensitive biologicals, thereby allowing a production of products that are not possible to be produced by existing methods. The suggested new PBV process comprises primary drying under vacuum from a partially frozen state (i.e. slush) at near subzero temperatures followed by stability drying at elevated temperatures (i.e., above 40 degrees Celsius). The new suggested method can be performed aseptically in unit doze format (in vials) and/or in bulk format (in trays, bags, or other containers). The drying can be performed as a continuous load process in a manifold vacuum dryer comprising a plurality (e.g., 30) of vacuum chambers attached to a condenser during the drying.
Owner:UNIVERSAL STABILIZATION TECH INC

Packet data analysis with efficient and flexible parsing capabilities

Methods and apparatus which facilitate the handling of data between platforms interconnected by any of a variety of network environments are disclosed. In general terms, the present invention represents an improvement over conventional packet parsing and searching mechanisms. The parse mechanism sequentially analyzes each character of the packet data and passes relevant characters to the search mechanism as soon as each character is reached. Preferably, the characters of each data field are parsed character-by-character. In one implementation, prior to searching a relevant data field, the parser initializes the appropriate search mechanism based on at least the data field type (e.g., the cookie field or URL field of an HTTP request). Each character of the relevant data is then passed sequentially to the search mechanism, where a search state are obtained for each passed character. Accordingly, the parser passes each character of the relevant data fields to the search mechanism. Since the parser passes the well-defined fields of standard protocols, such as HTTP and FTP, parsing may be efficiently performed without referencing memory (e.g., parsing is implemented in micro-code). When the parser reaches the end of the relevant data field, the parser may then cause the search mechanism to output search results associated with the search state of the last searched character. Alternatively, the parser may initiate another search for another data field, which is subsequently parsed and searched character-by-character as recited above for the first field.
Owner:CISCO TECH INC
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