Bipolar devices for modification of airways by transfer of energy

Abstract

This relates to a device for treating lung disease, and more particularly, relates to a device for exchanging energy with airway tissue such as that found in the airways of human lungs. The exchange of energy with this airway tissue in the airways reduces the ability of the airways to constrict and / or reduces the resistance within the airway to the flow of air through the airway.

Description

[0001]This is a Continuation-in-part application of U.S. application Ser. No. 09 / 296,040 filed Apr. 21, 1999, and of Continuation-in-part U.S. application Ser. No. 09 / 095,323 filed Jun. 10, 1998 both of which applications are incorporated herein by reference in their entirety.BACKGROUND OF THE INVENTION[0002]1. Field of the Invention[0003]The invention relates to a device for treating lung disease, and more particularly, the invention relates to a device for transferring energy into airway tissue such as that found in the airways of human lungs. This includes heating and applying RF energy to the airway. In the airways of the lung, the transfer of energy into the airway tissue stiffens that tissue or reduces the ability of the airways to constrict. In general the treatment reduces the resistance to the flow of air through the airway.[0004]2. Brief Description of the Related Art[0005]Asthma is a disease in which (i) bronchoconstriction, (ii) excessive mucus production, and (iii) infl...

AI Technical Summary

Benefits of technology

[0015]The present invention relates to a device for treating airway tissue within the lungs by transfer of energy into the walls of the airway to reduce plugging of the airway, to prevent the airway from being able to constrict, to increase the inner airway diameter, or to reduce resistance to flow through the airway. The invention is particularly directed to the treatment of the airways in the lungs to reduce the effects of asthma and other lung disease. One variation of the invention includes the transfer of energy to the airway wall via the application of heat.

[0016]The present invention provides devices to decrease airway responsiveness and airway resistance to flow which may augment or replace current management techniques. In accordance with one variation of the present invention, an energy transfer apparatus for treating conditions of the lungs by decreasing airway responsiveness includes transferring energy into an airway wall to alter the airway wall in such a manner that the responsiveness of the airway is reduced.

[0019]Another variation of the invention includes an expandable portion which includes pre-shaped tines. Such tines are configured to be in a first state within an elongated body and, when advanced out of the elongated body, to expand into a second expanded state. The tines may be connected to each other with an expanding element to prevent the tines from entering multiple airways at a bifurcation.

[0027]Yet another variation of the invention includes a deployment member comprising a handle adjacent to a proximal end of the elongated body. The elongated body may be slidably attached to the handle. The deployment member may also comprise a wire that extends from the handle through the lumen of the elongated body and is fixedly attached to the distal tip. This wire may also provide a current to the energy transfer members. The elongated body, the wire, and the distal tip may be slidably moveable in a distal and proximal direction. This variation of the deployment member may also include a stop configured to prevent distal movement of the wire beyond a deployment point. In this variation, beyond the deployment point, movement of the elongated body against the non-moving distal tip causes the expansion member to expand from a first state into a second expanded state.

[0031]Another variation of the inventive device includes a distal tip that may be configured to prevent gouging of the airway tissue. The distal tip may have a redundant joint to prevent separation of the tip from the apparatus. The distal tip may also be sized to fit within a bronchoscope.

[0040]The present invention may be used for a treatment of asthma or other constriction or spasm of a bodily conduit by application of energy. The treatment reduces the ability or propensity of the airway to contract, reduces plugging of the airway, increases the inner airway diameter, and / or reduces resistance to flow through the airway.

Problems solved by technology

Asthma is a disease in which (i) bronchoconstriction, (ii) excessive mucus production, and (iii) inflammation and swelling of airways occur, causing widespread but variable airflow obstruction thereby making it difficult for the asthma sufferer to breathe.

The chronic nature of asthma can also lead to remodeling of the airway wall (i.e., structural changes such as thickening or edema) which can further affect the function of the airway wall and influence airway hyperresponsiveness.

It may, however, be impractical and not always helpful to avoid all potential stimuli.

High doses of corticosteroid anti-inflammatory drugs can have serious side effects that require careful management.

Patient compliance with pharmacologic management and stimulus avoidance is often a barrier to successful asthma management.

Current management techniques are neither completely successful nor free from side effects.

In addition to the airways of the lungs, other body conduits such as the esophagus, ureter, urethra, and coronary arteries, are also subject to periodic spasms that interfere with their normal function.

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