Uterine cell collecting apparatus enabling self-collection of std, hpv, and cervical cells
The uterine cell collection device addresses the complexity and cost issues of conventional devices by using a cylindrical design with a guide portion and hinge-connected brush unit for intuitive and safe self-harvesting of uterine cells, enhancing usability and preventing contamination for non-technical users.
Patent Information
- Application Number
- PCT/KR2024/005922
- Authority / Receiving Office
- WO · WO
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2023-07-31
- Filing Date
- 2024-05-02
- Publication Date
- 2025-02-06
AI Technical Summary
Conventional uterine cell harvesting devices are complex and expensive, making them difficult for non-technical users to operate intuitively and safely for self-harvesting STD and HPV cells from the cervix and surrounding areas.
A uterine cell collection device with a cylindrical accommodation unit, a guide portion, and a brush unit with axial protrusions and wings connected via a hinge structure, allowing for easy insertion and collection of cells while preventing contamination and facilitating intuitive use.
The device enables easy and safe self-harvesting of uterine cells, ensuring intuitive usability and preventing contamination, making it accessible for non-technical users to collect and store samples for further examination.
Smart Images

Figure KR2024005922_06022025_PF_FP_ABST
Abstract
Description
A cervical cell collection device that allows for self-collection of STD, HPV, and cervical cells
[0001] The present invention relates to a uterine cell collection device capable of autologous collection of STD & HPV and cervical cells.
[0002] Typically, to screen for STDs, HPV, and the health of the uterus, cells are collected from the cervix and its surroundings and tested. In the future, users will be able to collect cells from the cervix and its surroundings themselves using a collection brush (e.g., a disposable brush). They will then be able to place the collected cells, along with a portion of the brush (e.g., the brush portion) containing the collected contents, in a vial and send it to a testing institution (e.g., a hospital) for testing. In this case, the collection brush that users use must be safe, intuitive, and easy to use.
[0003] At the boundary between the vagina and the uterus lies the cervix, a relatively narrow passageway. From the cervix, the internal cervix extends into the uterus, while from the cervix, the external cervix extends into the vagina. Within the cervix, the external cervix, internal cervix, and cervical canal are sequentially located from the vagina toward the uterus.
[0004] The shape of the cervix and its surroundings changes according to biological age and health status. For example, in young women, the external cervix is relatively wider than in older women, and the length of the cervix from the inside of the vagina to the inside of the uterus is also relatively wider and shorter than in older women. Here, when a user uses a collection brush at home, it needs to be intuitive and easy to use. However, conventional collection brushes have the disadvantage of being expensive due to their complex components, and their usability is not intuitive.
[0005] As the configuration of the exfoliated cell collection device is improved, there is a need to implement a technology that allows the user to use it intuitively and easily and to easily insert the used brush into a vial.
[0006] One purpose of the present invention is to provide a uterine cell collection device that is intuitive and easy to use, so that even non-experts and ordinary people can self-collect STD & HPV and cervical cells.
[0007] In one aspect, the present invention provides a uterine cell collection device, comprising: a body part including a cylindrical receiving portion; and a cylindrical passage part formed on a first side of the receiving portion and having an inner diameter smaller than that of the receiving portion; a guide part including a cylindrical rod part having an outer diameter smaller than or equal to the inner diameter of the passage part and capable of sliding within the passage part; and a brush part including one or more axial protrusions formed at an end of a second side opposite the first side of the receiving portion; one or more wings formed extending in at least one radial direction from the first brush; and one or more second brushes including one or more protrusions protruding from each wing onto a surface of the wing; wherein the brush part is connected to the guide part and moves according to the movement of the guide part.
[0008] In one embodiment, the first brush and each wing may be connected by a hinge structure.
[0009] In one embodiment, at a position where the brush portion is pulled outward from the second end of the receiving portion, the hinge may be unfolded so that the angle formed by each wing with respect to the axial direction is about 45 to 90°.
[0010] In one embodiment, the guide portion slides toward the first side relative to the extraction position, so that at the receiving position where the brush portion is received into the receiving portion, the hinge folds, so that the angle formed by each wing with respect to the axial direction is about 0 to 45°.
[0011] In one embodiment, the uterine cell collection device may further include a first receiving position jaw formed in the guide portion and in the form of a protrusion or recess; and a second receiving position jaw formed in the form of a recess or protrusion inside the receiving portion or inside the passage portion, in a complementary shape to the protrusion or recess of the first receiving position jaw at the axial position of the first receiving position jaw at the receiving position.
[0012] In one embodiment, an escape portion may be formed at the second end of the receiving portion, the escape portion having a hollow portion smaller than the inner diameter of the receiving portion and larger than the maximum diameter of the brush portion at the receiving position.
[0013] In one embodiment, the load section may further include a stopper having a width greater than the diameter of the hollow in at least one radial direction at an axial position inside the escape section at the extraction location.
[0014] In one embodiment, the brush portion may be forcibly fitted to the second end of the guide portion.
[0015] In one embodiment, the body portion may further include a separation jaw extending inwardly from the receiving portion so as to interfere with the brush portion but not interfere with the slide operation of the load portion at a separation position where the guide portion slides toward the first side relative to the receiving position. By the separation jaw interfering with the brush portion, the brush portion may be separated from the load portion or positioned in a state where it is capable of being separated.
[0016] In one embodiment, the guide portion may further include an operating portion formed on the first side of the load portion and positioned on the outside of the first side end of the passage portion, the operating portion having a width greater than the inner diameter of the passage portion in at least one radial direction.
[0017] In one embodiment, the operating member may have different widths in at least two radial directions.
[0018] In one embodiment, the body portion may further include an over-insertion prevention protrusion extending outwardly radially from an axial position that is about 1 / 10 to 1 / 2 the length of the receiving portion from the first side end of the receiving portion.
[0019] In one embodiment, the body portion may further include a hand rest portion extending in an outer radial direction of the passage portion.
[0020] In one embodiment, the load section may further include a wedge-shaped or springboard-shaped separation prevention step formed on the outer side of the load section with an inclined surface facing the second side so as to interfere with the second end of the passage section at an assembly position in which the guide section slides to the first side from the separation position.
[0021] In one embodiment, the brush portion may include about 4 to 12 wings and a second brush.
[0022] In one embodiment, each wing may be formed at the same angle as the adjacent wing.
[0023] In one embodiment, one or more of the protrusions of the first brush may have a longer axial protrusion length than any of the protrusions of the second brush.
[0024] In one embodiment, the first brush may include two or more protrusions.
[0025] In one embodiment, each protrusion of the first brush may be formed such that the protrusion closer to the axis has a longer axial protrusion length.
[0026] The uterine cell collection device according to an embodiment of the present invention can be used in a simple and intuitive manner to allow a third party or the subject to collect uterine cells and then store them to prevent contamination of the human body and the specimen.
[0027] Figure 1 is a front view illustrating a uterine cell collection device according to an embodiment of the present invention.
[0028] FIG. 2 is a front view showing the inside of a uterine cell collection device according to an embodiment of the present invention.
[0029] Figure 3 is a front view showing the inside of a uterine cell collection device according to an embodiment of the present invention.
[0030] Figure 4 is an enlarged front view of the brush section at the sampling location.
[0031] FIG. 5 is a front view and a bottom view showing the guide part of a uterine cell collection device according to an embodiment of the present invention in isolation.
[0032] Figure 6 is a plan view illustrating the brush portion of a uterine cell collection device according to an embodiment of the present invention in isolation.
[0033] Figure 7 is an enlarged view of a portion of Figure 5.
[0034] Figure 8 is an enlarged view of a portion of Figure 2.
[0035] Hereinafter, embodiments of the present invention will be described in detail with reference to the attached drawings. The present invention may be modified in various ways and may take various forms. Therefore, specific embodiments are illustrated in the drawings and described in detail in the text. However, this is not intended to limit the present invention to a specific disclosed form, but should be understood to include all modifications, equivalents, and substitutes included in the spirit and technical scope of the present invention. In describing each drawing, similar reference numerals are used to indicate similar components. In the attached drawings, the dimensions of structures are shown larger than actual size to ensure clarity of the present invention.
[0036] The terminology used in this application is only used to describe specific embodiments and is not intended to limit the present invention. The singular expression includes the plural expression unless the context clearly indicates otherwise. In this application, the terms "comprise" or "have" should be understood to indicate the presence of a feature, number, step, operation, component, or combination thereof described in the specification, but do not preclude the possibility of the presence or addition of one or more other features, numbers, steps, operations, components, or combinations thereof.
[0037] Unless otherwise defined, all terms used herein, including technical or scientific terms, have the same meaning as commonly understood by one of ordinary skill in the art to which this invention pertains. Terms defined in commonly used dictionaries should be interpreted as having a meaning consistent with their meaning in the context of the relevant technology, and will not be interpreted in an idealized or overly formal sense unless explicitly defined herein.
[0038] Figure 1 is a front view illustrating a uterine cell collection device according to an embodiment of the present invention.
[0039] Referring to FIG. 1, a uterine cell collection device according to an embodiment of the present invention may include a body part (10); a guide part (20); and a brush part (30); and the brush part (30) is connected to the guide part (20) and can move according to the movement of the guide part (20).
[0040] FIG. 2 is a front view showing the inside of a uterine cell collection device according to an embodiment of the present invention.
[0041] Referring to FIG. 2, the body portion (10) may include a cylindrical receiving portion (11); and a cylindrical passage portion (12) formed on a first side of the receiving portion (11) and having an inner diameter smaller than that of the receiving portion (11). The receiving portion (11) provides a space in which other components, such as a brush of the uterine cell collection device according to an embodiment of the present invention, can be received inside before and after collection. The passage portion (12) is formed to have an inner diameter smaller than that of the receiving portion (11), and a rod-shaped component can pass into the inside thereof, thereby forming a syringe-like structure. In one embodiment, the rod-shaped component may be a guide portion (20) described below.
[0042] Continuing with reference to FIG. 2, the guide portion (20) may include a cylindrical rod portion (21) that has an outer diameter that is smaller than or equal to the inner diameter of the passage portion (12) and can slide within the passage portion (12). The rod portion (21) has an outer diameter that is smaller than or equal to the inner diameter of the passage portion (12), and in particular, the rod portion (21) has an outer diameter that is equal to or slightly smaller than the inner diameter of the passage portion (12), so that the rod portion (21) can be guided without any interference or shaking when entering the passage portion (12) and sliding.
[0043] Fig. 3 is a front view illustrating the interior of a uterine cell collection device according to an embodiment of the present invention. Meanwhile, Fig. 2 illustrates the brush portion (30) in a receiving position where it is received within the receiving portion (11), while Fig. 3 illustrates the brush portion (30) in a collection position where it is protruded outward from the second end of the receiving portion (11).
[0044] Figure 4 is an enlarged front view of the brush section at the sampling location.
[0045] Referring to FIGS. 3 and 4 together, the brush portion (30) may include a first brush (31) including one or more axial protrusions formed at an end of a second side opposite the first side of the receiving portion (11); one or more wings (W30) formed to extend in at least one radial direction from the first brush (31); and one or more second brushes (32) including one or more protrusions protruding from each wing (W30) onto a surface of the wing (W30). The first brush (31) may perform a function of collecting cells from the endocervix, and the second brush (32) may perform a function of collecting cells from the external cervix. The first brush (31) and the second brush (32) may be dimensioned so as to perform the above functions.
[0046] Continuing with reference to FIGS. 3 and 4, in one embodiment, the first brush (31) and each wing (W30) may be connected by a hinge structure. In the context of the present specification, a "hinge structure" refers to any structure in which two or more members having a plate-like or plate-like shape are in contact and / or joined at each edge, and a connecting portion is formed that can be driven so that the angle formed by the two or more plate-like or plate-like members with respect to each other changes with the contact edge as an axis.
[0047] Continuing with reference to FIG. 4, a brush ball (33) having a hemispherical shape may be formed at the bottom of the hinge structure of the wing (W30). By forming the brush ball (33), frictional force may be reduced when the brush is pulled out of the body.
[0048] In one embodiment, in the connection portion of the brush portion (30) and the guide portion (20), complementary recesses and protrusions are formed, so that the connection force can be strengthened.
[0049] Referring to FIGS. 2 to 4 together, in one embodiment, at a collection position where the brush portion (30) is protruded outward from the second end of the receiving portion (11), the hinge is unfolded so that the angle formed by each wing (W30) with respect to the axial direction can be about 45 to 90°. In addition, in one embodiment, at a collection position where the guide portion (20) is slidably driven toward the first side relative to the collection position, where the brush portion (30) is received into the receiving portion (11), the hinge is folded so that the angle formed by each wing (W30) with respect to the axial direction can be about 0 to 45°. In general, according to the axial slide operation of the guide section (20), the brush section (30) is unfolded in a shape that allows for collection of the internal and external cervix at the collection position, and at the receiving position, the brush section (30) is folded so that the collected cells can be received in the receiving section (11) without contamination.
[0050] Referring to FIGS. 2 and 3, in one embodiment, an escape portion (13) having a hollow portion smaller than the inner diameter of the receiving portion (11) and larger than the maximum diameter of the brush portion (30) at the receiving position may be formed at the second end of the receiving portion (11). In addition, in one embodiment, the load portion (21) may further include a stopper (22) having a width larger than the diameter of the hollow portion in at least one radial direction at an axial position inside the escape portion (13) at the collection position. Through the shape of the escape portion (13) and the stopper (22) as described above, it is possible to prevent the brush portion (30) from being over-inserted by advancing further than the collection position.
[0051] The connection between the brush part (30) and the guide part (20) may be an integrated connection or a detachable connection. In one embodiment, the connection between the brush part (30) and the guide part (20) is a detachable connection, through which the brush part (30) and / or the guide part (20) may be exchanged. In one embodiment, the brush part (30) may be coupled to the second end of the guide part (20) by a forced fit. By being formed by a forced fit as described above, the brush part (30) may be separated from the guide part (20) by force and may be accommodated and / or stored in the receiving part (11). The separation by force may be performed by the slide driving of the guide part (20). The separation by force may be implemented by interference between the brush part (30) and the inside of the receiving part (11) in the slide driving by the guide part (20). In one embodiment, the body portion (10) may further include a separation jaw (not shown) extending inwardly of the receiving portion (11) so as to not interfere with the sliding operation of the load portion (21) but to interfere with the brush portion (30) at a separation position where the guide portion (20) slides to the first side relative to the receiving position. In one embodiment, the separation jaw may interfere with the first side of the stop jaw (22).
[0052] As long as the guide portion (20) includes the load portion (21), the addition of an additional shape is not excluded. In particular, since the load portion (21) performs a slide operation as described above, the guide portion (20) may have an additional shape added to facilitate application of an external force for the slide operation. In one embodiment, the guide portion (20) may further include an operating portion (23) formed on the first side of the load portion (21), positioned on the outer side of the first end of the passage portion (12), and having a width greater than the inner diameter of the passage portion (12) in at least one radial direction.
[0053] FIG. 5 is a front view and a bottom view showing the guide part of a uterine cell collection device according to an embodiment of the present invention in isolation.
[0054] Referring to FIG. 5, in one embodiment, the operating portion (23) may have different widths in at least two radial directions. In one embodiment, the operating portion (23) may have a flat shape extending only in one radial direction. As described above, since the operating portion (23) does not have a perfect circle, it is convenient for a user to operate the operating portion (23) by hand, and in particular, an external force can be conveniently applied to the guide portion (20) to rotate around an axis so that the brush portion (30) can reliably collect cells from the internal cervix and the external cervix at the collection location.
[0055] Meanwhile, although the guide part (20) is easy to insert through the passage part (12), it should not be easy to escape to the first side again so that separation of each member is prevented and the reliability of the overall device can be secured. Referring to FIG. 5 further, in order to implement this, in one embodiment, the load part (21) may further include a wedge-shaped or springboard-shaped separation prevention step (24) formed on the outer side of the load part (21) with an inclined surface facing the second side so as to interfere with the second-side end of the passage part (12) at an assembly position where the guide part (20) slides to the first side rather than the separation position. In one embodiment, the separation prevention step (24) may be a springboard-shaped step. In the context of this specification, a springboard type means a type of member in which a plate-like or plate-like shape having an inclined surface is connected to a main member, and when the inclined surface is pressed by an external force, the plate-like or plate-like shape moves toward the main member so that the angle formed by the inclined surface is lowered or becomes zero, and when the external force is removed, the member is formed to form an inclined surface again by elasticity, so that an external force from the direction in which the inclined surface is facing flows away, but an external force from the opposite direction resists.
[0056] Referring back to FIGS. 1 to 3, it will be apparent to those skilled in the art that when each member operates as described above, the receiving portion (11) can be inserted into the vagina of a subject when a user uses the uterine cell collection device according to an embodiment of the present invention. At this time, a safety device can be implemented on the body portion (10), particularly on the outer side of the receiving portion (11), to prevent injury to the subject due to excessive insertion. In one embodiment, the body portion (10) may further include an over-insertion prevention protrusion (14) extending in an outward radial direction from an axial position that is about 1 / 10 to 1 / 2 the length of the receiving portion (11) from the first end of the receiving portion (11). In order to perform the above function, the extent to which the over-insertion prevention protrusion (14) extends in the outward radial direction can be selected by those skilled in the art. For example, the above over-insertion prevention jaw (14) can form a maximum diameter that is 1 to 3 times longer than the outer diameter of the receiving portion (11).
[0057] Referring to FIGS. 1 to 3, as described above, the uterine cell collection device according to an embodiment of the present invention operates in a syringe-like manner by the sliding operation of the guide portion (20), so that when a user pushes or pulls the guide portion (20) axially, if a member that serves as a reference for the user to apply an external force to the body portion (10), which is a relatively fixed member, is formed, the relative sliding operation of the body portion (10) and the guide portion (20) can be more easily implemented. In one embodiment, the body portion (10) may further include a hand support portion (15) extending in the outer radial direction of the passage portion (12). In order to perform the above function, the extent to which the hand support portion (15) extends in the outer radial direction can be selected by those skilled in the art. For example, the hand support portion (15) may form a maximum diameter that is 1 to 5 times the outer diameter of the passage portion (12).
[0058] FIG. 6 is a plan view illustrating a brush portion of a uterine cell collection device according to an embodiment of the present invention in isolation. Referring to FIG. 6, in one embodiment, the brush portion (30) may include about 4 to 12 wings (W30) and second brushes (32). Although FIG. 6 illustrates that there are six wings (W30) and six second brushes (32), this is merely exemplary, and an appropriate number may be selected so that the wings (W30) and the second brushes (32) do not interfere with each other and cells from the external cervix can be stably and reliably collected. In addition, in one embodiment, each wing (W30) may be formed to be spaced apart from an adjacent wing (W30) at the same angle. Through this, the second brush (32) can apply a uniform force to the external cervix as a whole, thereby preventing injury to the subject and reducing the user's difficulty in use.
[0059] Referring also to FIG. 4, in one embodiment, at least one of the protrusions of the first brush (31) may have a longer axial protrusion length than any of the protrusions of the second brush (32). This allows the first brush (31) to collect cells from the endocervix while the second brush (32) collects cells from the external cervix. In one embodiment, the first brush (31) may include two or more protrusions. In one embodiment, the second brush (32) may include two or more protrusions. In one embodiment, the first brush (31) may include two or more protrusions, and each protrusion of the first brush (31) may be formed such that a protrusion closer to the axis has a longer axial protrusion length. When the first brush (31) collects cells from the endocervix through the above-described shape, the brush comes into contact with the wall of the endocervix in a relatively complementary shape, so that the first brush (31) can apply a uniform force to the endocervix as a whole, thereby preventing injury to the subject and reducing the user's difficulty in use.
[0060] Meanwhile, Fig. 7 is an enlarged drawing of a part of the guide part of Fig. 5, and Fig. 8 is an enlarged drawing of a part of the body part of Fig. 2.
[0061] Referring to FIGS. 7 and 8, in one embodiment, the uterine cell collection device may further include a first receiving position jaw (41) formed in the guide portion (20) and in the form of a protrusion or recess; and a second receiving position jaw (42) formed in the form of a recess or protrusion inside the receiving portion (11) or inside the passage portion (12) in a complementary form to the protrusion or recess of the first receiving position jaw (41) at an axial position of the first receiving position jaw (41) at the receiving position. That is, the first receiving position jaw (41) and the second receiving position jaw (42) may be fastened to each other in a complementary form at the receiving position. Through this, the guide portion is formed so that it can be moved out of the receiving position only when a certain level or more of force is applied, and it does not move out of the receiving position during transport, and it allows the subject to accurately know the receiving position during use. In FIGS. 7 and 8, the first receiving position jaw (41) is illustrated as a protrusion and the second receiving position jaw (42) is illustrated as a recess having a complementary shape to the protrusion, but this is merely exemplary, and the first receiving position jaw (41) may be a recess and the second receiving position jaw (42) may be a protrusion. In addition, in FIGS. 7 and 8, the first receiving position jaw (41) and the second receiving position jaw (42) are illustrated as being fastened at an axially upper portion inside the passage portion (12), but this is merely exemplary, and the first receiving position jaw (41) and the second receiving position jaw (42) may be positioned at any axial position where the guide portion (20) and a portion of the body portion (10) can be engaged and fastened. In one embodiment, the second receiving position jaw (42) may be formed inside the passage portion (12).
[0062] Hereinafter, embodiments of the present invention will be described. However, the embodiments described below are merely some embodiments of the present invention, and the scope of the present invention is not limited to the embodiments described below.
[0063] Collection of uterine cells
[0064] A uterine cell collection device according to an embodiment of the present invention is prepared. The device is inserted into the vagina until the device's over-insertion prevention bar interferes and the insertion is stopped. By operating the operating unit, the brush unit is pushed into the body's escape unit so that it exits and advances toward the vaginal opening while the guide unit and the brush unit are connected. At this time, the brush unit unfolds and exits. When the brush unit is in contact with the cervix, the operating unit is operated to rotate the brush unit 3 to 5 times to collect cells. When collection is complete, the operating unit is pulled so that the brush unit re-enters the body's receiving unit. At this time, the brush unit is folded.
[0065] Separation of the brush part
[0066] The guide section is pulled by manipulating the operating section. The brush section interferes with the separating jaw, and the brush section is separated from the load section. At this time, the separation can be completed by rotating the operating section. By separation, the brush section remains separated from the load section and is located within the receiving section.
[0067] Separate storage of brush section
[0068] Prepare a storage vial. By manipulating the operating section to push the guide section back in, the brush section is again ejected toward the storage vial. This time, the brush section is separated from the load section, so the ejection completely separates the brush section from the device according to the embodiment of the present invention and places it in the storage vial.
[0069] The brush portion containing the collected cells is stored in a storage vial so that it can be transported for subsequent testing.
[0070] Although the present invention has been described above with reference to preferred embodiments thereof, it will be understood by those skilled in the art that various modifications and changes may be made to the present invention without departing from the spirit and scope of the present invention as set forth in the claims below.
[0071] [Explanation of symbols]
[0072] 10: Body
[0073] 11: Reception area
[0074] 12: Passageway
[0075] 13: Escape Room
[0076] 14: Over-insertion prevention jaw
[0077] 15; Hand rest
[0078] 20: Guide Department
[0079] 21: Road Department
[0080] 22: Stopper
[0081] 23: Control panel
[0082] 24: Separation barrier
[0083] 30: Brush section
[0084] 31: First brush
[0085] 32: Second brush
[0086] 33: Brushball
[0087] 41: First receiving position jaw
[0088] 42: Second receiving position jaw
[0089] W30: Wing
Claims
1. A body part including a cylindrical receiving portion; and a cylindrical passage part formed on a first side of the receiving portion and having an inner diameter smaller than that of the receiving portion; A guide part including a cylindrical rod part having an outer diameter smaller than or equal to the inner diameter of the passage part and capable of sliding within the passage part; and A brush unit comprising: a first brush including one or more axial protrusions formed at an end of a second side opposite to the first side of the receiving portion; one or more wings formed extending in at least one radial direction from the first brush; and one or more second brushes including one or more protrusions protruding from each wing onto a surface of the wing; The above brush part is connected to the guide part and moves according to the movement of the guide part. Uterine cell collection device.
2. In paragraph 1, The above first brush and each wing are connected by a hinge structure, Uterine cell collection device.
3. In paragraph 2, At the extraction position where the brush portion is protruded outward from the second end of the receiving portion, the hinge is spread so that the angle formed by each wing with respect to the axial direction becomes 45 to 90°, The guide portion slides to the first side relative to the collecting position, so that at the receiving position where the brush portion is received into the receiving portion, the hinge folds so that the angle formed by each wing with respect to the axial direction becomes 0 to 45°. Uterine cell collection device.
4. In paragraph 3, A first receiving position jaw formed in the guide portion and in the form of a protrusion or recess; and a second receiving position jaw formed in the form of a recess or protrusion inside the receiving portion or inside the passage portion, in a complementary shape to the protrusion or recess of the first receiving position jaw at the axial position of the first receiving position jaw at the receiving position; Uterine cell collection device.
5. In paragraph 3, At the second end of the receiving portion, an escape portion is formed that has a hollow portion smaller than the inner diameter of the receiving portion and larger than the maximum diameter of the brush portion at the receiving position. The above load section further includes a stopper having a width greater than the diameter of the hollow in at least one radial direction at an axial position inside the escape section at the above extraction location. Uterine cell collection device.
6. In paragraph 3, The above brush portion is forcibly fitted to the second end of the guide portion, Uterine cell collection device.
7. In paragraph 6, The body part further includes a separation jaw extending inwardly from the receiving part so as to not interfere with the slide operation of the load part but to interfere with the brush part at a separation position where the guide part slides to the first side relative to the receiving position. Uterine cell collection device.
8. In paragraph 1, The above guide portion further includes an operating portion formed on the first side of the load portion and located on the outer side of the first side end of the passage portion, and having a width greater than the inner diameter of the passage portion in at least one radial direction. Uterine cell collection device.
9. In paragraph 8, The above operating part has different widths in at least two radial directions, Uterine cell collection device.
10. In paragraph 1, The body part further includes an over-insertion prevention protrusion extending in an outward radial direction from an axial position that is 1 / 10 to 1 / 2 of the length of the receiving part from the first side end of the receiving part. Uterine cell collection device.
11. In paragraph 1, The above body portion further includes a hand support portion extending in the outer radial direction of the passage portion, Uterine cell collection device.
12. In paragraph 7, The above load section further includes a wedge-shaped or springboard-shaped separation prevention step formed on the outside of the load section with an inclined surface facing the second side so as to interfere with the second side end of the passage section at an assembly position where the guide section slides to the first side from the separation position. Uterine cell collection device.
13. In paragraph 1, The brush portion includes 4 to 12 wings and a second brush. Uterine cell collection device.
14. In paragraph 13, Each of the above wings is formed at the same angle as the adjacent wing, Uterine cell collection device.
15. In paragraph 1, At least one of the protrusions of the first brush has an axial protrusion length longer than any of the protrusions of the second brush, Uterine cell collection device.
16. In paragraph 1, The first brush includes two or more protrusions, Each protrusion of the first brush is formed such that the protrusion closer to the axis has a longer axial protrusion length, Uterine cell collection device.
Citation Information
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