Blood component separator and exhaust device thereof

Abstract

The present invention discloses a blood component separator and an exhaust device thereof. The exhaust device comprises a support frame, the support frame comprises an extrusion fixed plate, and also comprises an extrusion movable plate arranged on the support frame and a driving mechanism arranged on the support frame for driving the extrusion movable plate to move toward the extrusion fixed plate. A clamping cavity for clamping an external blood bag is formed between the extrusion movable plate and the extrusion fixed plate. The width of the clamping cavity gradually increases from the rear end to the front end. The rear end of the clamping cavity clamps the lower part of the blood bag, and the front end of the clamping cavity clamps the upper part of the blood bag. The driving mechanism is used to drive the extrusion movable plate to exhaust the blood bag, so that the gas can be exhausted more thoroughly and more intelligently. The width of the clamping cavity gradually increases from the rear end to the front end, so during the extrusion process, the lower part of the blood bag is squeezed first and then slowly squeezed to the upper part of the blood bag, thereby squeezing the air from the lower part of the blood bag to the upper part (at the blood bag bag mouth conduit), thereby obtaining a better exhaust effect.

Description

Technical Field

[0001] The invention relates to the technical field of fully automatic blood component preparation, and in particular to an exhaust device and a blood component separator using the exhaust device. Background Art

[0002] After the whole blood bag is separated by the centrifuge, the blood will be layered, with the plasma layer on the top, the white film layer (platelets, a very small amount, very thin layer) in the middle, and the red blood cell layer on the bottom. The blood component separator is used to separate a bag of blood into several small bags of blood or to separate the components after the centrifuge. The separation process is: hang the whole blood bag on the front side of the blood component separator, squeeze the plasma layer (or white film layer) on the blood bag through the squeezing plate to make it flow into the empty collection bag along the catheter to achieve the purpose of component separation. The component blood is transferred to different blood bags and stored in different environments. When the patient needs a certain component blood, it can be conveniently taken at any time.

[0003] Plasma is separated from whole blood and transferred to a plasma collection bag. Air is inevitably mixed in the blood separation and transfer process. After the plasma separation is completed, the air in the plasma bag needs to be removed, and then the plasma bag is placed at -35°C for quick freezing, and then placed in a -20°C environment for storage. This treatment can keep the plasma for about one year. In general, the plasma in the blood bag is relatively full. If the air in the bag is not removed first but directly frozen, the plasma will coagulate and increase in volume. Due to the mixing of air, the space for plasma expansion is relatively small, and the blood bag is easily burst. If the air in the bag is removed first and then frozen, the expansion space of the plasma will increase, and the blood bag will not be so easy to burst. At present, the manual control method is mainly used to remove the air in the plasma bag, which makes the operation cumbersome, the labor intensity of the workers is very high, and there will be relatively large human errors. Summary of the invention

[0004] The main purpose of the present invention is to provide a blood component separator and an exhaust device thereof, aiming to facilitate the exhaust operation of a plasma bag.

[0005] In order to achieve the above-mentioned purpose, the present invention provides an exhaust device, including a support frame, the support frame including an extrusion fixed plate, the exhaust device also including an extrusion movable plate arranged on the support frame and a driving mechanism arranged on the support frame for driving the extrusion movable plate to move toward the extrusion fixed plate, a clamping cavity for clamping an external blood bag is formed between the extrusion movable plate and the extrusion fixed plate, the width of the clamping cavity gradually increases from the rear end to the front end, the rear end of the clamping cavity is used to clamp the lower part of the blood bag, and the front end of the clamping cavity is used to clamp the upper part of the blood bag.

[0006] Preferably, the extrusion surface of the extrusion movable plate toward the extrusion fixed plate forms an arc-shaped convex surface, and the highest point of the arc-shaped convex surface is located at the rear end of the extrusion movable plate.

[0007] Preferably, the support frame includes a bottom plate, the bottom plate is the extrusion fixed plate, and the extrusion movable plate is located above the bottom plate;

[0008] The support frame further includes an axis core and left and right side plates arranged on the left and right sides of the bottom plate, the two ends of the axis core are respectively fixed to the left and right side plates, the rear end of the extrusion movable plate extends to form an extension portion, a first through hole is opened between the extension portion and the rear end of the extrusion movable plate along the width direction, and the axis core passes through the first through hole;

[0009] The front end of the bottom plate is bent and tilted upward, the front end of the extrusion movable plate is bent and tilted upward and close to the bottom plate, the driving mechanism is fixedly connected to the bottom plate, the extension part is driven and connected to the driving mechanism and is driven by the driving mechanism to move up and down, so that the front and rear ends of the extrusion movable plate move in the opposite direction relative to the extension part.

[0010] Preferably, the driving mechanism includes a driving member, a driving rod drivingly connected to the driving member, and a clamping member sleeved on the driving rod, the driving member is fixedly arranged at the bottom of the rear end of the base plate, the driving rod passes through the base plate, the clamping member moves up and down driven by the driving rod, the clamping member has a clamping opening, and the extension portion extends into the clamping opening.

[0011] Preferably, the driving member is a screw motor, the driving rod is a screw pair, the screw pair includes a screw and a screw nut, the clamping member has a second through hole, the screw nut is fixed in the second through hole, and the support frame also includes a guide groove, the clamping member is placed in the guide groove, and due to the restriction of the guide groove, the clamping member moves up and down linearly along the screw as the screw nut cannot rotate.

[0012] Preferably, the support frame also includes an upper cover plate, which is located above the extension portion. The support frame also includes a rear cover plate, which is located at the rear end of the base plate and perpendicular to the base plate. The rear cover plate, the upper cover plate, and the left and right side plates form a cavity, and the drive rod, the clamping member and the extension portion are placed in the cavity.

[0013] Preferably, the bottom plate is made of a transparent material or the bottom plate is provided with a transparent window.

[0014] Preferably, the support frame includes a base plate, the driving mechanism includes a screw motor and a screw pair, the screw motor is fixed at the bottom of the base plate, the extrusion movable plate is located above the base plate, the rear end of the extrusion movable plate extends to form an extension portion, the screw pair passes through the base plate and is connected with the extension portion of the rear end of the extrusion movable plate, driving the extrusion movable plate to move up and down; the extrusion surface of the extrusion movable plate is inclined, and the support frame also includes an inclined side plate, which is the extrusion fixed plate; the inclined side plate is fixedly connected to the base plate, and the connection between the inclined side plate and the base plate encloses a accommodating groove for supporting the blood bag; the support frame also includes a guide rod, which passes through the base plate and is connected with the extension portion of the rear end of the extrusion movable plate, the screw pair includes a screw and a screw nut, the screw nut is restricted by the guide rod and cannot rotate but moves up and down linearly along the screw, and the extrusion movable plate moves up and down linearly along the screw with the screw nut.

[0015] Preferably, a baffle is installed on the side wall of the clamping member, a support member is installed on the driving member, two slot-type photoelectric sensors are installed on the support member, and the baffle passes through the slots of the two slot-type photoelectric sensors when the driving rod moves.

[0016] Preferably, the exhaust device further comprises a gravity sensor, wherein the gravity sensor is fixed below the support frame, and the support frame is fixed to the separator body through the gravity sensor, and the gravity sensor is used to detect the weight of the entire support frame.

[0017] The present invention also provides a blood component separator, comprising a body, a mounting assembly for connecting the support frame and the separator body, and any one of the above-mentioned exhaust devices.

[0018] In the exhaust device of the blood component separator of the present invention, a driving mechanism is used to drive the extrusion moving plate to exhaust the blood bag, which can make the gas exhaust more thorough and more intelligent. In addition, since the width of the clamping cavity gradually increases from the rear end to the front end, the rear end of the clamping cavity is used to clamp the lower part of the blood bag, and the front end of the clamping cavity is used to clamp the upper part of the blood bag, so during the extrusion process, the lower part of the blood bag is squeezed first and then slowly squeezed to the upper part of the blood bag, thereby squeezing the air from the lower part of the blood bag to the upper part (the blood bag bag mouth catheter), and obtaining a better exhaust effect. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 It is a schematic structural diagram of a first embodiment of an exhaust device of a blood component separator of the present invention;

[0020] Figure 2 for Figure 1 An exploded view of the exhaust assembly shown;

[0021] Figure 3 for Figure 1 A schematic diagram of the structure of the extrusion moving plate and the driving mechanism in the exhaust device shown;

[0022] Figure 4 for Figure 1 The schematic diagram of the structure of the exhaust device shown in the figure without the upper cover plate;

[0023] Figure 5 It is a schematic structural diagram of a second embodiment of the exhaust device of the blood component separator of the present invention;

[0024] Figure 6 for Figure 5 The schematic diagram of the structure of the exhaust device shown is shown without the mounting plate;

[0025] Figure 7 It is a schematic diagram of the structure of the blood component separator of the present invention. DETAILED DESCRIPTION

[0026] The following will be combined with the drawings in the embodiments of the invention to clearly and completely describe the technical solutions in the embodiments of the invention. Obviously, the described embodiments are only part of the embodiments of the invention, not all of the embodiments. Based on the embodiments in the invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the invention.

[0027] It should be noted that all directional indications in the embodiments of the invention (such as up, down, left, right, front, back, etc.) are only used to explain the relative position relationship, movement, etc. between the components under a certain specific posture (as shown in the accompanying drawings). If the specific posture changes, the directional indication will also change accordingly.

[0028] refer to Figure 1 , Figure 5 As shown, the exhaust device 10 includes a support frame 11, and the support frame 11 can be semi-enclosed, such as a box with an opening, or fully open. The support frame 11 includes an extrusion fixed plate (the bottom plate 12 in the first embodiment and the inclined side plate 23 in the second embodiment). The exhaust device 10 also includes an extrusion movable plate 13 arranged on the support frame 11 and a driving mechanism 14 ( Figure 5In the embodiment, the driving mechanism 14 is located inside the mounting plate 27), and a clamping cavity for clamping the external blood bag 2 is formed between the extrusion movable plate 13 and the extrusion fixed plate (12 or 23). The width of the clamping cavity gradually increases from the rear end to the front end. The rear end of the clamping cavity is used to clamp the lower part of the blood bag 2, and the front end of the clamping cavity is used to clamp the upper part of the blood bag 2, that is, the distance between the extrusion movable plate 13 and the extrusion fixed plate (12 or 23) gradually increases from the rear end for clamping the lower part of the blood bag 2 to the front end for clamping the upper part of the blood bag 2. During the exhaust process, the blood bag 2 is placed in the clamping cavity with the catheter of the blood bag 2 facing outward (for heat sealing), and then the driving mechanism 14 is started, and the extrusion movable plate 13 moves toward the extrusion fixed plate (12 or 23) driven by the driving mechanism 14. Since the width of the clamping cavity gradually increases from the rear end to the front end, during the squeezing process, the lower part of the blood bag 2 is squeezed first and then slowly squeezed to the upper part of the blood bag 2, thereby squeezing the air from the lower part of the blood bag 2 to the upper part (the bag opening conduit of the blood bag 2), so that the air is discharged more thoroughly.

[0029] Further, refer to Figure 2 , Figure 6 As shown. The extrusion surface of the extrusion movable plate 13 toward the extrusion fixed plate (12 or 23) forms an arc-shaped convex surface, and the highest point of the arc-shaped convex surface is located at the rear end 132 of the extrusion movable plate (that is, the rear end of the extrusion surface forms an arc-shaped convex portion, and the arc-shaped convex portion extends to the front end of the extrusion movable plate). The rear end 132 of the extrusion movable plate contacts the lower part of the blood bag 2. During the exhaust process, the highest point of the arc-shaped convex surface will first contact the lower part of the blood bag 2, and the extrusion movable plate 13 will continue to move toward the extrusion fixed plate, and the front end 131 of the extrusion movable plate will contact the upper part of the blood bag 2, thereby achieving the purpose of squeezing the air from the lower part of the blood bag 2 upward (at the bag mouth conduit of the blood bag 2) so that the air is discharged more thoroughly.

[0030] Further, refer to Figures 1 to 4 As shown, Figures 1 to 4It is the first embodiment of the exhaust device of the present invention. The bottom of the support frame 11 includes a bottom plate 12, and the extrusion movable plate 13 is located above the bottom plate 12. The bottom plate 12 is an extrusion fixed plate, and the front end 121 of the bottom plate is bent and tilted upward. The support frame 11 also includes an axis core 17 and left and right side plates (15 and 16) that are perpendicular and connected to the left and right sides of the bottom plate 12. The two ends of the axis core 17 are respectively fixed to the left and right side plates (15 and 16) by nuts. The rear end 132 of the extrusion movable plate extends to form an extension 133, and a first through hole 134 is opened between the extension 133 and the rear end 132 of the extrusion movable plate along the width direction, and the axis core 17 passes through the first through hole 134. The driving mechanism 14 is fixedly connected to the bottom plate 12, and the front end 131 of the extrusion movable plate is bent and tilted upward to approach the bottom plate 12. The extension part 133 is connected to the driving mechanism 14 and is driven by the driving mechanism 14 to move up and down, so that the front and rear ends (131 and 132) of the squeezing movable plate 13 move in the opposite direction relative to the extension part 133. The clamping cavity formed between the bottom plate 12 and the squeezing movable plate 13 of this embodiment is inclined upward, which is convenient for the operator to put the blood bag 2 into the clamping cavity.

[0031] Furthermore, a receiving recess is formed at the rear end 122 of the bottom plate, and a peripheral edge (not shown) is extended upward from the edge of the bottom plate 12. In addition to being able to better accommodate the blood bag 2, the peripheral edge can more importantly be used to increase the accommodation space within the surface of the bottom plate 12 and has a certain storage function. In the case that the blood bag 2 is squeezed, ruptured or leaks, it can prevent the plasma in the blood bag 2 from directly flowing to other parts (such as the outer shell) of the blood component separator 1 or the inside of the machine (where the electric control board is located) to cause harm.

[0032] In this embodiment, based on the consideration of mechanics and optics, the rear end 122 of the bottom plate is bent upward, and the ratio of the bending height to the span of the bottom plate 12 supporting frame 11 is designed to be 0.15-0.6; of course, it is preferably designed to be an arc-shaped bending shape. On the one hand, the bottom plate 12 with this curved design is more conducive to the exhaust of the blood bag 2. More importantly, according to the principle of optical refraction, after the blood bag 2 is clamped, the surface is attached to the inner surface of the bottom plate 12, and the blood donation barcode label on the blood bag 2 is observed on the outer surface of the bottom plate 12 with a relatively straight optical visual effect, which is more convenient for being scanned and identified by a barcode gun.

[0033] Further, the driving mechanism 14 includes a driving member 141, a driving rod 142 drivingly connected to the driving member 141, and a clamping member 143 connected to the driving rod 142. The driving member 141 is fixedly arranged at the bottom of the rear end of the bottom plate 12, the driving rod 142 penetrates the bottom plate 12, and the clamping member 143 moves up and down under the drive of the driving rod 142. The clamping member 143 has a clamping opening, and the extension 133 extends into the clamping opening. The extension 133 moves up and down with the clamping member 143. The driving mechanism 14 is fixedly connected to the bottom plate 12 through the connecting member 144. Furthermore, the driving member 141 is a screw motor, the driving rod 142 is a screw pair, the screw pair includes a screw and a screw nut, the clamping member 143 has a second through hole 145, the screw nut is fixed in the second through hole 145, the support frame 11 also includes a guide groove 146, the clamping member is placed in the guide groove 146, and due to the restriction of the guide groove 146, the clamping member 143 moves linearly up and down along the screw as the screw nut cannot rotate.

[0034] Furthermore, the support frame 11 further includes an upper cover plate 18, which is located above the extension 133. The support frame 11 further includes a rear cover plate 19, which is located at the rear end of the bottom plate 12 and is perpendicular to the bottom plate 12. The rear cover plate 19, the upper cover plate 18, and the left and right side plates (15 and 16) form a cavity, and the driving rod 142, the clamping member 143, and the extension 133 are placed in the cavity. The overall surface looks more beautiful. The upper cover plate 18 and the rear cover plate 19, the left and right side plates (15 and 16) can be fixedly connected by screws or glued.

[0035] Furthermore, the bottom plate 12 is made of a transparent material or is provided with a transparent window. The bottom plate 12 is made of a transparent material such as resin, acrylic, etc., so that it is convenient for the operator to visually monitor the blood bag 2 placed in the exhaust device 10 (such as leakage, or poor exhaust, etc.). In addition, a barcode label is attached to the surface of the blood bag 2. Designing the first bottom plate 12 to be transparent can facilitate the use of a barcode gun to scan and identify the barcode label. In other embodiments, it is not necessary to design the entire bottom plate 12 to be transparent, but only to set a transparent window in a part of the bottom plate 12, which can also achieve the same effect as above.

[0036] A baffle 147 is installed on the side wall of the clamping member 143, a support member is installed on the driving member 141, and two slot-type photoelectric sensors 148 are installed on the support member. The baffle 147 passes through the slots of the two slot-type photoelectric sensors 148 when the driving rod 142 moves. The two slot-type photoelectric sensors 148 are used to limit the initial position and the end position of the movement of the clamping member 143.

[0037] refer to Figure 5 , Figure 6 As shown, Figure 5 , Figure 6 Another embodiment of the exhaust device 10 of the present invention is shown. In this embodiment, the driving mechanism 14 includes a screw motor 20, a screw 21 drivingly connected to the screw motor 20, and a screw nut 22 sleeved on the screw 21. The support frame 11 includes a base plate 24, the screw motor 20 is fixed at the bottom of the base plate 24, the extrusion movable plate 13 is located above the base plate 24, the screw 21 penetrates the base plate 24 and is connected to the extension of the rear end of the extrusion movable plate 13, driving the extrusion movable plate 13 to move up and down. The extrusion surface of the extrusion movable plate 13 is inclined, and the support frame 11 also includes an inclined side plate 23, which is an extrusion fixed plate, and the inclined side plate 23 is fixedly connected to the base plate 24. The connection between the inclined side plate and the base plate encloses a receiving groove for supporting the blood bag. The support frame 11 also includes a guide rod 25, which penetrates the base plate 24 and is connected to the extension of the rear end of the extrusion movable plate 13; the screw motor 20 drives the screw 21 with the screw nut 22 to rotate, and the screw nut 22 is restricted by the guide rod 25 and cannot rotate, but moves up and down along the screw 21, and the extrusion movable plate 13 moves up and down along the screw 21 along with the screw nut 22. When descending, the extrusion movable plate 13 moves along the screw 21 along the screw nut 22 and is extruded toward the inclined side plate 23. The support frame 11 includes a mounting plate 27, which is embedded in the body of the separator 1 through the mounting plate 27.

[0038] The exhaust device 10 further includes a gravity sensor 30 , which is fixed below the support frame 11 . The support frame 11 is fixed to the body of the separator 1 through the gravity sensor 30 . The gravity sensor 30 is used to detect the weight of the entire support frame 11 .

[0039] During the exhaust process, the color of the liquid in the pipeline is monitored in real time using a color sensor. When the gas is exhausted and red blood cells are discharged, the color sensor can detect the red blood cells. Then the information that the gas is exhausted is transmitted to the main control board, and the main control board controls the driving mechanism 14 to stop squeezing the blood bag 2. The present invention uses a color sensor, which can be used after color calibration. It will not be affected or disturbed by external light during use, and the detection result is more accurate.

[0040] refer to Figure 7As shown, an embodiment of the present invention further provides a blood component separator 1, which includes a body, a mounting assembly for connecting a support frame 11 and the body of the separator 1, and the aforementioned exhaust device 10, which is mounted on the body to clamp the blood bag 2 during blood component separation, and to squeeze the blood bag 2 before heat sealing to remove the air in the blood bag 2, so as to facilitate subsequent cryopreservation. The structure of the body of the blood component separator 1 does not belong to the improved content of this application. For the description of the structure and shape of the body part, those skilled in the art can refer to the patent specification and drawings of No. 201410209746.3 previously applied by the applicant.

[0041] The invention is not limited to the above embodiments. Various changes can be made under the technical content disclosed in the above embodiments. Any equivalent structural transformation made by using the invention description and the contents of the drawings, or directly or indirectly applied in other related technical fields, are also included in the patent protection scope of the invention.

Claims

1. An exhaust device, comprising a support frame, characterized in that: The support frame includes an extrusion fixed plate, and the exhaust device also includes an extrusion movable plate arranged on the support frame and a driving mechanism arranged on the support frame for driving the extrusion movable plate to move toward the extrusion fixed plate. A clamping cavity for clamping an external blood bag is formed between the extrusion movable plate and the extrusion fixed plate, and the width of the clamping cavity gradually increases from the rear end to the front end. The rear end of the clamping cavity is used to clamp the lower part of the blood bag, and the front end of the clamping cavity is used to clamp the upper part of the blood bag; the extrusion movable plate forms an arc-shaped convex surface toward the extrusion surface of the extrusion fixed plate, and the highest point of the arc-shaped convex surface is located at the rear end of the extrusion movable plate; the exhaust device also includes a gravity sensor, which is fixed below the support frame, and the support frame is fixed to the separator body through the gravity sensor, and the gravity sensor is used to detect the weight of the entire support frame.

2. The exhaust device according to claim 1, characterized in that: The support frame includes a bottom plate, the bottom plate is the extrusion fixed plate, and the extrusion movable plate is located above the bottom plate; The support frame further includes an axis core and left and right side plates arranged on the left and right sides of the bottom plate, the two ends of the axis core are respectively fixed to the left and right side plates, the rear end of the extrusion movable plate extends to form an extension portion, a first through hole is opened between the extension portion and the rear end of the extrusion movable plate along the width direction, and the axis core passes through the first through hole; The front end of the bottom plate is bent and tilted upward, the front end of the extrusion movable plate is bent and tilted upward and close to the bottom plate, the driving mechanism is fixedly connected to the bottom plate, the extension part is driven and connected to the driving mechanism and is driven by the driving mechanism to move up and down, so that the front and rear ends of the extrusion movable plate move in the opposite direction relative to the extension part.

3. The exhaust device according to claim 2, characterized in that: The driving mechanism includes a driving member, a driving rod drivingly connected to the driving member, and a clamping member sleeved on the driving rod. The driving member is fixedly arranged at the bottom of the rear end of the base plate, the driving rod penetrates the base plate, and the clamping member moves up and down under the drive of the driving rod. The clamping member has a clamping opening, and the extension portion extends into the clamping opening.

4. The exhaust device according to claim 3, characterized in that: The driving member is a screw motor, the driving rod is a screw pair, the screw pair includes a screw and a screw nut, the clamping member is provided with a second through hole, the screw nut is fixed in the second through hole, the supporting frame also includes a guide groove, the clamping member is placed in the guide groove, and due to the restriction of the guide groove, the clamping member moves linearly up and down along the screw as the screw nut cannot rotate.

5. The exhaust device according to claim 3, characterized in that: The support frame also includes an upper cover plate, which is located above the extension portion. The support frame also includes a rear cover plate, which is located at the rear end of the base plate and is perpendicular to the base plate. The rear cover plate, the upper cover plate, and the left and right side plates form a cavity, and the drive rod, the clamping member, and the extension portion are placed in the cavity.

6. The exhaust device according to claim 3, characterized in that: The bottom plate is made of a transparent material or is provided with a transparent window.

7. The exhaust device according to claim 1, characterized in that: The support frame includes a base plate, the driving mechanism includes a screw motor and a screw pair, the screw motor is fixed to the bottom of the base plate, the extrusion movable plate is located above the base plate, the rear end of the extrusion movable plate extends to form an extension portion, the screw pair penetrates the base plate and is connected with the extension portion of the rear end of the extrusion movable plate, driving the extrusion movable plate to move up and down; the extrusion surface of the extrusion movable plate is inclined, and the support frame also includes an inclined side plate, which is the extrusion fixed plate; the inclined side plate is fixedly connected to the base plate, and the connection between the inclined side plate and the base plate encloses a accommodating groove for supporting the blood bag; the support frame also includes a guide rod, which penetrates the base plate and is connected with the extension portion of the rear end of the extrusion movable plate, the screw pair includes a screw and a screw nut, the screw nut is restricted by the guide rod and cannot rotate but moves up and down linearly along the screw, and the extrusion movable plate moves up and down linearly along the screw with the screw nut.

8. The exhaust device according to any one of claims 1 to 6, characterized in that: A baffle is installed on the side wall of the clamping member, a support member is installed on the driving member, two slot-type photoelectric sensors are installed on the support member, and the baffle passes through the slots of the two slot-type photoelectric sensors when the driving rod moves.

9. A blood component separator, comprising a body, characterized in that: It also includes a mounting assembly for connecting the support frame to the separator body and an exhaust device as described in any one of claims 1 to 8.

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