A probe packaging structure of a human body pressure measurement sensor

Abstract

The present invention discloses a probe packaging structure of a human body pressure measurement sensor, including: a wire, a pressure chip power supply and signal transmission; a protective tube, provided with a groove, one end of which is sealed and connected to a plastic conduit, and the other end is a closed end; a micro PCB, placed in the groove, and its signal output end is connected to the wire; a pressure chip, placed in the groove and its sensing surface is perpendicular to the opening direction of the groove; a transition wire, connecting the pressure chip and the micro PCB; a protective glue is filled in the gap between the pressure chip and the protective tube, and the protective glue is filled on the surface of the pressure chip; a low-stress medium is filled between the pressure chip and the micro PCB. The chip of the present invention is subjected to minimal external stress, ensuring that the output value fluctuation of the packaged sensor is minimal, the time drift is minimal, the risk of short circuit is avoided, and the stability of the pressure chip test value is improved, thereby effectively improving the accuracy of pressure monitoring.

Description

Technical Field

[0001] The invention relates to the technical field of pressure monitoring, in particular to a probe packaging structure of a human body pressure measuring sensor. Background Art

[0002] With the advent of the information age, sensor technology has become an important technical foundation of the information society. Sensors are increasingly used in pressure monitoring in medicine. It can be foreseen that with the maturity of manufacturing technology and the continuous improvement of device performance, sensors will further promote the rapid development of medicine in the near future. As the most advanced device of medical equipment, sensors can convert human physiological signals into medical electrical signals. They are widely used in the medical field and can be used to measure temperature, blood flow velocity, pressure, etc. The application of sensors in pressure detection in the human body has put forward higher measurement requirements for pressure measurement and also shown attractive prospects.

[0003] Intracranial pressure monitoring is a real-time monitoring method that uses an intracranial pressure monitor and corresponding sensors to dynamically measure the intracranial pressure of a patient, and records and reflects the patient's intracranial status in the form of numerical values, pressure waveform display, alarms, etc. The common characteristics of existing intracranial pressure sensors are: a pressure chip is embedded in the monitoring part of the sensor probe, and the pressure chip and the wire are connected by a soft transition wire. There is an airway in the internal structure, which consists of two parts: the airway inside the sensor metal probe and the airway inside the sensor wire, so that the air hole of the pressure chip is connected to the outside atmosphere; when it is used, the sensor probe is implanted in the brain tissue, and the brain tissue exerts pressure on the sensing surface of the pressure chip in the cranial cavity. When this pressure acts vertically on the chip, the deformation of the chip sensing surface is the largest; when this pressure is greater than the atmospheric pressure, the pressure chip sensing surface is deformed, thereby changing the resistance of the chip and the voltage output by the chip. This voltage change signal is processed to obtain the relative intracranial pressure value. However, when the existing sensor pressure chip is packaged, the placement of the pressure chip is affected by the wires connected to the pressure chip, causing it to shift, and the stress generated by the rebound of the transition wires connected to the pressure chip, which leads to problems that are easy to occur during measurement: 1) Uneven force during pressure detection causes large fluctuations in measurement data; 2) The sensor output has a large time drift; The collected data cannot truly reflect the patient's intracranial pressure, thereby misleading the judgment of medical staff and affecting the patient's treatment. Summary of the invention

[0004] The purpose of the present invention is to provide a probe packaging structure for a human body pressure measurement sensor, which is used to solve the problem in the prior art that when the pressure chip of the intracranial pressure sensor is packaged, the placement of the pressure chip is affected by the wires connected to the pressure chip, causing the pressure chip to be offset, and the stress generated by the rebound of the wires connected to the pressure chip causes large fluctuations and drifts in the measurement data of the detection sensor, resulting in the measurement data not being able to truly reflect the intracranial pressure.

[0005] The present invention solves the above problems through the following technical solutions:

[0006] A probe packaging structure of a human body pressure measurement sensor, comprising:

[0007] A wire is placed in the plastic conduit, and a first end of the wire is connected to the signal processing circuit;

[0008] A protection tube is provided with a groove, one end of the protection tube is sealed and connected to the plastic conduit, and the other end is a closed end;

[0009] A miniature PCB is placed in the groove, and a signal output end of the miniature PCB is connected to the second end of the wire;

[0010] The pressure chip is placed in the groove and arranged on one side of the micro PCB along the opening direction of the groove, with its sensing surface perpendicular to the opening direction of the groove and facing the outside of the groove;

[0011] A transition wire connects the signal output end of the pressure chip and the signal input end of the micro PCB for electrical signal transmission;

[0012] A low-stress medium is filled between the pressure chip and the micro PCB;

[0013] The gap between the pressure chip and the side wall of the protection tube groove is filled with protective glue, and the surface of the pressure chip perpendicular to the opening direction of the groove is filled with protective glue, and the pressure chip is suspended in the groove.

[0014] principle:

[0015] The micro PCB is placed in the groove, and the protective glue is used to fix and insulate it with the side wall of the protective tube. The pressure chip is initially fixed to the micro PCB board below it using a transition wire. The gap between the pressure chip and the protective tube is filled with protective glue. The pressure chip is suspended in the groove using the support force of the transition wire and the fixing of the protective glue. The problem that the measurement data of the detection sensor cannot truly reflect the intracranial pressure due to the large fluctuation and drift of the measurement data caused by the displacement of the pressure chip due to the influence of the wire connected to the pressure chip, and the stress generated by the rebound of the wire connected to the pressure chip, etc., is solved. When any slight deformation of the protective tube acts on the pressure chip through the protective glue, the pressure chip is only pulled in the horizontal direction parallel to the chip sensing surface, but not in the vertical direction of the pressure chip sensing surface, thereby ensuring that the external stress on the pressure chip is minimized and improving the accuracy of the strain test. The protective glue plays the role of insulation protection and initial fixation, including but not limited to epoxy glue, silicone, etc., so that the side wall of the pressure chip is effectively isolated from the side wall of the groove of the protective tube, without the risk of short circuit, improving the stability of the pressure chip test value, and effectively improving the accuracy of intracranial pressure monitoring. Furthermore, a low-stress medium is filled between the bottom of the pressure chip and the micro-PCB. The low-stress medium includes non-corrosive gas, low-stress silicone or oil, etc. Among them, the non-corrosive gas includes dry gas, inert gas, etc., which plays a role in insulating and protecting the pressure chip and the micro-PCB, further improving the accuracy of intracranial pressure monitoring.

[0016] Furthermore, the closed end portion is a closed end cap integrally formed with the protection tube.

[0017] Furthermore, the connection between the protection tube and the plastic conduit is encapsulated with protective glue. The sensing surface of the pressure chip is also encapsulated with protective glue, so that the protection tube can smoothly transition when inserted into the human body. The protective glue plays a lubricating and protective role, and can be made of silicone or epoxy glue.

[0018] Furthermore, the protection tube is made of relatively magnetically inert and biocompatible materials, and the relatively magnetically inert and biocompatible materials include titanium-based metals, cobalt-based metals, ceramics or Peek polymer materials.

[0019] Biocompatible materials have no sensitization, carcinogenicity, or teratogenicity when in contact with the human body, and can be well integrated with bone tissue, epithelium, and connective tissue.

[0020] Furthermore, the transition wire is a metal wire with low resistance (high conductivity) such as gold or silver with a diameter not greater than 35 μm. Its advantages are: good conductivity and very low stress. Furthermore, the medium with minimum stress is low stress silicone, non-corrosive gas or oil.

[0021] Furthermore, the protective glue is silicone glue or epoxy glue.

[0022] Furthermore, the outer surface of the plastic catheter is provided with scale markings to facilitate observation of implantation depth during use.

[0023] Compared with the prior art, the present invention has the following advantages and beneficial effects:

[0024] (1) In the present invention, the gap between the pressure chip and the protective tube is filled with protective glue, so that when any slight deformation of the protective tube acts on the pressure chip through the protective glue, the pressure chip is pulled only in the horizontal direction parallel to the chip sensing surface, but not in the vertical direction of the pressure chip sensing surface. The external stress on the pressure chip is minimized, thereby ensuring that the output value fluctuation and time drift of the packaged sensor are minimized.

[0025] (2) The protective glue has insulating properties, which effectively isolates the side wall of the pressure chip from the side wall of the groove of the protection tube, without the risk of leakage, improving the stability of the pressure chip test value, thereby effectively improving the accuracy of intracranial pressure monitoring.

[0026] (3) The present invention uses a transition wire to initially fix the pressure chip, so that it is easy to adjust the chip position during the installation process. The transition wire is made of a high conductivity material such as gold or silver. BRIEF DESCRIPTION OF THE DRAWINGS

[0027] Figure 1 A top view of the present invention;

[0028] Figure 2 It is a structural cross-sectional view of the present invention;

[0029] Figure 3 A structural cross-sectional view of another embodiment of the present invention;

[0030] Figure 4 for Figure 2 Schematic diagram of the structure along the AA direction;

[0031] Among them, 1-plastic catheter; 2-protective tube; 3-pressure chip; 4-micro PCB; 5-wire; 6-transition wire. DETAILED DESCRIPTION

[0032] The present invention is further described in detail below in conjunction with examples, but the embodiments of the present invention are not limited thereto.

[0033] Embodiment 1:

[0034] Combined with Figure 1 , Figure 2 and 4 As shown, a probe packaging structure of a human body pressure measurement sensor includes:

[0035] A wire 5 is placed in the plastic conduit 1, and a first end of the wire 5 is connected to a signal processing circuit;

[0036] The protection tube 2 is provided with a groove, one end of the protection tube 2 is sealed and connected to the plastic conduit 1, and the other end is a closed end;

[0037] The micro PCB 4 is placed in the groove. The size of the micro PCB 4 matches the inner diameter of the protection tube 2 so that it can be placed in the groove. The gap between the micro PCB 4 and the side wall of the protection tube 2 is filled with protective glue to fix the position of the micro PCB 4. The signal output end of the micro PCB 4 is connected to the second end of the wire 5.

[0038] The pressure chip 3 is placed in the groove and its sensing surface is perpendicular to the opening direction of the groove, and the sensing surface of the pressure chip 3 faces the outside of the groove;

[0039] The transition wire 6 connects the signal output end of the pressure chip 3 and the signal input end of the micro PCB 4 for electrical signal transmission. The pressure chip 3 is suspended in the groove and arranged on one side of the micro PCB 4 along the opening direction of the groove. Figure 3 As shown, the transition conductor 6 can be arranged on a side close to or away from the closed end;

[0040] The gap between the pressure chip 3 and the side wall of the groove of the protection tube 2 is filled with protective glue, and the surface of the pressure chip 3 perpendicular to the opening direction of the groove is filled with protective glue.

[0041] A low stress medium is filled between the pressure chip 3 and the micro PCB.

[0042] The micro PCB 4 is placed in the groove, and is fixed and insulated to the side wall of the protective tube 2 by protective glue. The pressure chip 3 is initially connected and fixed to the micro PCB 4 below it by the transition wire 6. The gap between the pressure chip 3 and the protective tube 2 is filled with protective glue. The pressure chip 3 is suspended in the groove by the support force of the transition wire 6 and the fixation of the protective glue. The problem that the position of the pressure chip 3 is offset by the influence of the wire connected to the pressure chip 3, and the stress caused by the rebound of the transition wire 6 connected to the pressure chip 3 causes large fluctuations in the measurement data of the detection sensor and the measurement data cannot truly reflect the intracranial pressure is solved. When any slight deformation of the protective tube 2 acts on the pressure chip 3 through the protective glue, the pressure chip 3 is only pulled in the horizontal direction parallel to the sensing surface of the pressure chip 3, and there is no pulling in the vertical direction of the sensing surface of the pressure chip 3, thereby ensuring that the external stress on the pressure chip 3 is minimized and improving the accuracy of the strain test. The protective glue plays the role of insulation protection and initial fixation, including but not limited to epoxy glue, silicone, etc., so that the side wall of the pressure chip 3 is effectively isolated from the side wall of the groove of the protection tube 2, without the risk of short circuit, and the stability of the test value of the pressure chip 3 is improved, thereby effectively improving the accuracy of human pressure monitoring. Furthermore, a low-stress medium such as non-corrosive gas, low-stress silicone or oil is filled between the bottom of the pressure chip 3 and the micro PCB4 to play the role of insulation protection for the pressure chip 3 and the micro PCB4, further improving the accuracy of human pressure monitoring.

[0043] It is worth noting that the probe packaging structure is not only used for intracranial pressure monitoring, but is also feasible for pressure monitoring of other parts of the human body.

[0044] Embodiment 2:

[0045] On the basis of Example 1, the closed end portion is a closed end cap integrally formed with the protection tube 2 .

[0046] Furthermore, the outer layers of the protective tube 2 and the closed end are both made of relatively magnetically inert and biocompatible materials. Relative magnetic inertness means that it does not contain magnetic metals such as iron. Relative magnetic inertness and biocompatible materials include titanium-based metals, cobalt-based metals, ceramics or Peek polymer materials. They are not allergenic, carcinogenic, or teratogenic when in contact with the human body, and can be well combined with bone tissue, epithelium, and connective tissue.

[0047] Embodiment 3:

[0048] On the basis of Example 1, the closed end is a closed end made of encapsulated soft glue, and further, the gap formed by the height difference between the sensing surface of the pressure chip 3 and the protective tube 2 is also filled with encapsulated soft glue, so that the protective tube 2 can smoothly transition when inserted into the human body. The encapsulated soft glue has the function of lubrication and protection, and also belongs to the protective glue, which can be made of silicone or epoxy glue.

[0049] Embodiment 4:

[0050] Based on Example 1, the transition wire 6 is a low-resistance metal wire with a diameter not greater than 35 μm, such as a gold wire, a silver wire or an aluminum wire.

[0051] Furthermore, the outer surface of the plastic catheter 1 is provided with scale markings to facilitate observation of the implantation depth during use.

[0052] Although the present invention is described herein with reference to the illustrative embodiments of the present invention, the above embodiments are only preferred embodiments of the present invention, and the embodiments of the present invention are not limited to the above embodiments. It should be understood that those skilled in the art can design many other modifications and embodiments, which will fall within the scope and spirit of the principles disclosed in this application.

Claims

1. A probe packaging structure of a human body pressure measurement sensor, characterized in that: include: A wire is placed in the plastic conduit, and a first end of the wire is connected to the signal processing circuit; A protection tube is provided with a groove, one end of the protection tube is sealed and connected to the plastic catheter, and the other end is a closed end, a protective glue is encapsulated at the connection between the protection tube and the plastic catheter, and the protection tube is made of a relatively magnetically inert and biocompatible material; A miniature PCB is placed in the groove, and a signal output end of the miniature PCB is connected to the second end of the wire; The pressure chip is placed in the groove and arranged on one side of the micro PCB along the opening direction of the groove, and its sensing surface is perpendicular to the opening direction of the groove; A transition wire connects the signal output end of the pressure chip and the signal input end of the micro PCB for electrical signal transmission; A low-stress medium is filled between the pressure chip and the micro PCB, and the low-stress medium is low-stress silicone, non-corrosive gas or oil; The gap between the pressure chip and the side wall of the protective tube groove is filled with protective glue, and the surface of the pressure chip perpendicular to the groove opening direction is filled with protective glue. The pressure chip is initially connected and fixed to the micro PCB board below it using a transition wire. The pressure chip is suspended in the groove using the supporting force of the transition wire and the fixing of the protective glue.

2. The probe packaging structure of a human body pressure measurement sensor according to claim 1, characterized in that: The relatively magnetically inert and biocompatible material is titanium-based metal, cobalt-based metal, ceramic or Peek polymer material.

3. The probe packaging structure of a human body pressure measurement sensor according to claim 1, characterized in that: The transition conductor is a metal conductor with a diameter or width not greater than 35 μm.

4. The probe packaging structure of a human body pressure measurement sensor according to claim 3, characterized in that: The metal wire is made of metal with high conductivity.

5. The probe packaging structure of a human body pressure measurement sensor according to claim 1, characterized in that: The protective glue is silica gel or epoxy glue.

6. The probe packaging structure of a human body pressure measurement sensor according to claim 1, characterized in that: The outer surface of the plastic conduit is provided with scale markings.

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