An automatic blood sample mixing device and a blood cell analysis device

Abstract

The present invention discloses an automatic blood sample mixing device and a blood cell analysis device. The automatic blood sample mixing device includes a second bracket and a third bracket. A test tube bin is provided on the third bracket, and a test tube tray is provided on the second bracket for abutting against the bottom of a blood sample collection test tube to accommodate the blood sample collection test tube in the test tube bin. The bottom of the blood sample collection test tube generates a rotary swing and vibration relative to the third bracket along with the second horizontal bracket, and the test tube bin is relatively stationary to constrain the tube body of the blood collection test tube, so that the bottom of the blood collection test tube has a relatively large swing. The automatic blood sample mixing device and the blood cell analysis device of the present invention can automatically and fully mix trace samples without manual treatment, saving labor and time costs and improving the working efficiency of mixing trace samples.

Description

Technical Field

[0001] The present invention belongs to the technical field of blood cell analysis. More specifically, the present invention relates to an automatic blood sample mixing device and a blood cell analysis device. Background Art

[0002] At present, there are two blood collection methods for routine blood tests: collecting venous blood and collecting peripheral blood. Among them, the amount of venous blood collected is large, at the milliliter (ml) level, which is suitable for patients such as adults who are convenient for blood collection; while the amount of peripheral blood collected is small, about 100 microliters (ul), which is suitable for patients such as children who are inconvenient for blood collection. Since the amount of peripheral blood sample is relatively small compared to the venous blood sample, the sample volume is too small, and the two are not of the same order of magnitude. Currently, for the models of blood cell analyzers with mechanical automatic mixing devices, the main method for mixing the samples in the test tube is to simulate the manual method of repeatedly inverting the test tube back and forth, or swinging and rotating, that is, swinging around the central axis of the test tube or a vertical line at a point on its extension line. However, the above mechanical automatic mixing method is only applicable to the mixing of venous blood samples and cannot meet the requirements for mixing trace peripheral blood samples in the test tube, and is not suitable for mixing peripheral blood samples in the test tube. When analyzing and detecting peripheral blood samples, most of them use manual shaking of peripheral blood test tubes for mixing, with low work efficiency and inconvenient sample mixing operation.

[0003] Therefore, it is necessary to propose an automatic mixing device suitable for mixing trace blood samples. Summary of the Invention

[0004] The present invention aims to solve the problems existing in the above-mentioned prior art to a certain extent, and provides an automatic blood sample mixing device and method, so as to automatically and fully mix trace blood samples, without manual handling, saving labor and time costs, and improving the work efficiency of mixing trace blood samples.

[0005] To this end, an embodiment of the present invention provides an automatic blood sample mixing device. The automatic blood sample mixing device includes a second bracket and a third bracket. A test tube bin is provided on the third bracket. A test tube tray is provided on the second bracket, which is used to support the bottom of the blood sample collection test tube to accommodate the blood sample collection test tube in the test tube bin. The bottom of the blood sample collection test tube generates a rotary swing and vibration relative to the third bracket along with the second horizontal bracket, and the test tube bin is relatively stationary to restrict the tube body of the blood collection test tube, so that the bottom of the blood collection test tube has a relatively large swing.

[0006] In one embodiment, the automatic blood sample mixing device further includes a first bracket, a first driving unit, an eccentric block, and a flexible module. The second bracket is fixedly connected above the first bracket through the flexible module. The first driving unit is disposed on the second bracket, and the eccentric block is fixed to the output shaft end of the first driving unit. Driven by the first driving unit, the eccentric block rotates around the axis of the first driving unit, driving the second bracket to perform a rotary swing and vibration relative to the first bracket, and further driving the test tube supported and fixed on the second bracket to synchronously perform a rotary swing and vibration.

[0007] In one embodiment, the automatic blood sample mixing device further includes a support rod, and the first bracket and the third bracket are connected through the support rod.

[0008] In one embodiment, the test tube tray is provided with a concave curved surface for abutting against the bottom of the test tube to accommodate the test tube in the test tube chamber.

[0009] In one embodiment, a first hollow groove and a second hollow groove are provided on the second bracket. A part of the support rod is disposed in the first hollow groove, the flexible module is a flexible column, and a part of the flexible column is located in the second hollow groove.

[0010] In one embodiment, a third hollow groove is formed in a side portion of the second bracket. The third hollow groove is a circular arc structure with one side open; the number of the support rods is two, and a part of one support rod is disposed in the first hollow groove, and a part of the other support rod is disposed in the third hollow groove.

[0011] In one embodiment, the test tube chamber includes a hollow shaft sleeve. The hollow shaft sleeve is disposed on the top of the third bracket, and a through hole is formed in the third bracket corresponding to the hollow shaft sleeve. The hollow shaft sleeve and the through hole are used to accommodate the test tube to restrict the movement position of the test tube.

[0012] In one embodiment, the flexible column is made of rubber or silica gel material, or is a spring.

[0013] In one embodiment, a concave platform is provided on a side portion of the second bracket, and the second hollow groove is provided on the concave platform. The flexible column includes an upper column head and a column body. The upper column head is disposed on the surface of the concave platform, the column body is disposed in the second hollow groove, the cross section of the upper column head is a circular structure, the column body is a cylindrical structure, and the diameter of the cross section of the circular structure of the upper column head is larger than the diameter of the cylindrical structure of the column body.

[0014] In one embodiment, the flexible column includes a lower column head, a connector is provided below the lower column head, and a connection hole is provided on the first bracket. The connector passes through the connection hole to fix the flexible column on the first bracket.

[0015] Compared with the prior art, implementing the blood sample automatic mixing device of the present invention has the following beneficial effects: Driven by the first driving unit, the eccentric block fixed to the output shaft end of the first driving unit rotates around the axis of the first driving unit. Since the vibration module fixed with the first driving unit is connected and fixed above the first bracket through the flexible module, and the rotation axis hole of the eccentric block is not at its center of gravity, when the eccentric block rotates, it drives the vibration module to swing and vibrate in a rotary manner. Since the blood sample collection tube containing the sample to be mixed is arranged on the test tube tray of the second bracket, the swing and vibration of the vibration module will drive the test tube on the test tube tray to swing and vibrate in a rotary manner, so as to achieve the purpose of automatically mixing the sample, without manual handling, saving labor and time costs, and improving the working efficiency of mixing trace blood samples; moreover, the blood sample automatic mixing device provided by the present invention has a relatively simple and compact structure, which is beneficial to the miniaturization of the instrument.

[0016] As the same inventive concept, according to the second aspect, the embodiment of the present invention further provides a blood cell analysis device, which includes the above-mentioned blood sample automatic mixing device. The blood cell analysis device further includes an automatic feeding device. The automatic feeding device includes a base and a transmission component. A second driving unit is fixed on the base. The transmission component is movably arranged on the base. The transmission component is connected to the first bracket. The second driving unit drives the transmission component to move relative to the base, and the transmission component drives the first bracket to move to move the test tube chamber to the preparation position for receiving the blood sample collection tube.

[0017] In one embodiment, the transmission component includes a sliding block, a sliding guide rail, a fixed block, a moving push plate and a sliding screw nut mechanism. The sliding guide rail is fixed on the base, and the slider is arranged in the sliding guide rail; the sliding screw nut mechanism is respectively connected to the second driving unit and the moving push plate; the fixed block is respectively connected to the first bracket and the slider; the moving push plate pushes the fixed block and the slider to move under the action of the sliding screw nut mechanism, and the slider moves along the sliding guide rail to guide the moving direction of the fixed block.

[0018] In one embodiment, a light coupling shielding piece is fixed on the moving push plate, and a detection light coupling is arranged on the base. The detection light coupling and the light coupling shielding piece cooperate to detect the moving position of the moving push plate.

[0019] In one embodiment, the blood cell analysis device further includes a test tube gripper. The test tube gripper first performs a descending action together with the micro peripheral blood collection test tube it grabs. The descending height is such that the bottom of the test tube touches or approaches a rubber test tube holder with a concave curved surface fixed on the second horizontal bracket. Then, the test tube gripper performs a horizontal feed and moves in a direction away from the test tube rack to a horizontal ready position, so that the test tube gripper is completely separated from the clamped test tube.

[0020] Compared with the prior art, the blood cell analysis device implementing the present invention has the following beneficial effects:

[0021] The present invention discloses a blood cell analysis device, which includes an automatic feeding device and an automatic blood sample mixing device. First, the automatic feeding device includes a base and a transmission assembly. The second driving unit drives the transmission assembly to move, and uses the movement of the transmission assembly to drive the first bracket to move. Since the test tube bin is arranged on the third bracket, the test tube bin can be moved to the preparation position for receiving the blood sample collection test tube, thereby realizing the automatic feeding of the blood sample collection tube. Secondly, under the drive of the first driving unit, the eccentric block fixed to the output shaft end of the first driving unit rotates around the axis of the first driving unit. Since the vibration module fixed to the first driving unit is connected and fixed above the first bracket through a flexible module, and the rotation axis hole of the eccentric block is not at its center of gravity, when the eccentric block rotates, it drives the vibration module to perform a rotary swing and vibration. Since the blood sample collection test tube containing the sample to be mixed is arranged on the test tube tray of the first bracket, the swing and vibration of the vibration module will drive the test tube on the test tube tray to perform a rotary swing and vibration, so as to achieve the purpose of automatically mixing the sample, without manual handling, saving labor and time costs, and improving the working efficiency of mixing micro blood samples.

[0022] To make the above objects, features, and advantages of the present invention more obvious and understandable, the following specifically enumerates preferred embodiments and, in conjunction with the accompanying drawings, makes a detailed description as follows. Description of the Drawings

[0023] To more clearly illustrate the technical solutions of the embodiments of the present invention, the following will briefly introduce the drawings required to be used in the embodiments. It should be understood that the following drawings only show some embodiments of the present invention, and therefore should not be regarded as a limitation of the scope. For those of ordinary skill in the art, without creative efforts, other related drawings can also be obtained based on these drawings.

[0024] Figure 1 It is a schematic structural diagram of the automatic blood sample mixing device according to the embodiment of the present invention;

[0025] Figure 2 It is a schematic diagram of the test tube bin of the embodiment of the present invention moving to the preparation position for receiving the test tube to be mixed.

[0026] In the figure, there are a first bracket 1, a second bracket 2, a third bracket 3, an eccentric block 4, a shock-absorbing column 5, a first motor 6, a test tube tray 7, a first hollow groove 8, a second hollow groove 9, a test tube bin 10, a support rod 11, a concave platform 12, an upper column head 13, a column body 14, a third hollow groove 15, a test tube 16, a base 17, a second motor 18, a sliding block 19, a sliding guide rail 20, a fixed block 21, a moving push plate 22, a sliding screw nut mechanism 23, a light-shielding opto-coupler flap 24, a detection opto-coupler 25, and a test tube gripper 26. Specific embodiments

[0027] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Usually, the components of the embodiments of the present invention described and shown in the accompanying drawings here can be arranged and designed in various different configurations. Therefore, the following detailed description of the embodiments of the present invention provided in the accompanying drawings is not intended to limit the scope of the claimed present invention, but only represents the selected embodiments of the present invention. All other embodiments obtained by those skilled in the art based on the embodiments of the present invention without creative efforts fall within the scope of protection of the present invention.

[0028] In the description of the present invention, it should be noted that the orientation or positional relationship indicated by the terms "center", "upper", "lower", "left", "right", "vertical", "inner", "outer", etc. is based on the orientation or positional relationship shown in the accompanying drawings. It is only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation. Therefore, it should not be construed as a limitation of the present invention. In addition, the terms "first", "second", "third" are only used for descriptive purposes and cannot be construed as indicating or implying relative importance.

[0029] In the description of the present invention, it should be noted that unless otherwise clearly specified and limited, the terms "installation", "connection", "connection" should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be directly connected or indirectly connected through an intermediate medium, and it can be the communication inside two elements. For those of ordinary skill in the art, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0030] As Figure 1As shown, an embodiment of the present invention provides an automatic blood sample mixing device, which can be used for mixing trace blood samples, such as fingertip blood samples. Specifically, the automatic blood sample mixing device includes a main body and a vibration module. A test tube chamber is provided on the main body. The vibration module includes a first driving unit, an eccentric block, and a test tube support module. The first driving unit, the eccentric block, and the test tube support module are connected in sequence. The test tube support module is used to abut against the bottom of the blood sample collection test tube so that the blood sample collection test tube is accommodated in the test tube chamber. The first driving unit drives the eccentric block to rotate, driving the test tube support module and the bottom of the blood sample collection test tube to perform a swinging motion to mix the blood sample in the blood sample collection test tube. According to the above description, and Figure 1 as recorded, it can be known that the eccentric block, the main body, and the vibration module are linked with the blood sample collection test tube accommodated in the test tube chamber. The eccentric block performs an eccentric motion driven by the first driving unit, which can drive the bottom of the blood sample collection test tube in the test tube chamber. The upper part of the blood sample collection test tube is located in the test tube chamber and can move in the test tube chamber to achieve automatic mixing of the sample in the test tube.

[0031] In the automatic blood sample mixing device according to the embodiment of the present invention, under the drive of the first driving unit, the eccentric block fixed to the output shaft end of the first driving unit rotates around the axis of the first driving unit. Since the vibration module fixing the first driving unit is connected and fixed above the main body, and the rotation axis hole of the eccentric block is not at its center of gravity, the rotation of the eccentric block drives the vibration module to perform a rotary swing and vibration. Since the blood sample collection test tube containing the sample to be mixed is arranged on the test tube tray of the main body, the swing and vibration of the vibration module will drive the test tube on the test tube tray to perform a rotary swing and vibration to achieve the purpose of automatically mixing the sample, without manual processing, saving labor and time costs, and improving the working efficiency of mixing trace blood samples.

[0032] Furthermore, in an embodiment, the vibration module further includes a flexible module. One end of the flexible module is arranged on the test tube support module, and the other end is fixed to the main body.

[0033] In the embodiment of the present invention, the flexible module is made of a flexible material. The setting of the flexible module is to enable the test tube support module to perform a better rotary swing, thereby driving the blood sample collection test tube to swing and achieving sufficient mixing.

[0034] In one embodiment, the body includes a first bracket and a third bracket, the test tube support module includes a second bracket, and the first bracket and the third bracket are connected by a support rod to fix the third bracket on the first bracket; the eccentric block is disposed on the first bracket, and the first driving unit is disposed on the second bracket; one end of the flexible module is connected to the first bracket and the other end is connected to the second bracket; the test tube bin is disposed on the third bracket. Preferably, the second bracket is located between the first bracket and the third bracket.

[0035] In the embodiment of the present invention, the first bracket can perform an eccentric motion around the motor rotating shaft under the action of the eccentric block and the first driving unit, and then drive the second bracket to perform a rotary swing relative to the first bracket and the third bracket through the flexible module. At this time, since the test tube support is fixed on the second bracket, when the second bracket performs a rotary swing, it will drive the test tube to synchronously perform a rotary swing, realizing sufficient mixing of the blood sample in the test tube.

[0036] In one embodiment, a test tube tray is disposed on the second bracket, and the test tube tray is provided with a concave curved surface for abutting against the bottom of the test tube to accommodate the test tube in the test tube bin.

[0037] In this embodiment, the concave curved surface forms a cavity, and a part of the bottom of the test tube containing the sample to be mixed is disposed in the cavity, so that the test tube is supported. The test tube tray and the test tube bin cooperate to fix the test tube containing the sample to be mixed on the blood sample automatic mixing device. During the mixing operation, the test tube tray drives the bottom of the test tube to perform a rotary swing and vibration to realize sufficient mixing of the blood sample in the test tube.

[0038] In one embodiment, a first hollow groove and a second hollow groove are disposed on the second bracket. A part of the support rod is disposed in the first hollow groove, the flexible module is a flexible column, and a part of the flexible column is located in the second hollow groove. And the first hollow groove should have enough space to enable the support rod to move in the first hollow groove; a part of the flexible column is located in the second hollow groove, and the output shaft of the first driving unit is connected to the eccentric block.

[0039] In this embodiment, according to the above description, and Figure 1 as recorded, it can be seen that the eccentric block, the flexible module, the second bracket, and the test tube tray are linked with the test tube accommodated in the test tube bin. When the eccentric block rotates around the axis of the first driving unit to perform an eccentric motion, it can drive the test tube in the test tube bin to perform a rotary swing to realize automatic mixing of the sample in the test tube.

[0040] Specifically, when mixing the blood sample in this embodiment, the test tube containing the blood sample to be mixed is placed in the test tube chamber, and the bottom of the test tube is supported by the test tube tray, so the test tube will be restricted within the test tube chamber. The test tube chamber should have sufficient space to enable the test tube to move within the test tube chamber during the mixing operation. Driven by the first driving unit, the eccentric block fixed to the output shaft end of the first driving unit rotates around the axis of the first driving unit. Since the second bracket fixing the first driving unit is connected and fixed above the first bracket through a flexible column, and the rotation axis hole of the eccentric block is not at its center of gravity, the eccentric block drives the second bracket to swing and vibrate in a rotary manner when rotating. Since the test tube containing the sample to be mixed is arranged on the test tube tray of the second bracket, the swing and vibration of the second bracket will drive the test tube on the test tube tray to swing and vibrate in a rotary manner, so as to achieve the purpose of automatically mixing the sample without manual treatment, saving labor and time costs, and improving the working efficiency of mixing trace blood samples.

[0041] Preferably, the first driving unit is preferably but not limited to a DC brushless motor, and the DC brushless motor is controlled and driven by a controller. It should be noted that according to technical experience, the first driving unit can also be selected as other mechanisms capable of providing driving force, and the specific selection of the first driving unit is not exhausted in the embodiments of the present invention.

[0042] Preferably, the test tube tray is preferably but not limited to being made of flexible materials such as rubber or silica gel. The DC brushless motor is driven for a certain time, and the eccentric block rotates around the motor shaft accordingly, further driving the second horizontal bracket to swing and vibrate in a rotary manner; the trace peripheral blood collection test tube placed on the rubber test tube holder with an inner concave curved surface fixed on the second horizontal bracket has its bottom swing and vibrate in a rotary manner along with the second horizontal bracket, and the test tube chamber is relatively stationary to restrict the tube body of the trace peripheral blood collection test tube. The bottom of the trace peripheral blood collection test tube swings relatively greatly; thus, the blood sample in the trace peripheral blood collection test tube is mixed under the combined influence of centrifugal shaking and vibration, while preventing the fragmentation of blood cells.

[0043] In one embodiment, the first hollow groove is circular, a part of the support rod passing through the first hollow groove is cylindrical, and the diameter of the circular first hollow groove is larger than the diameter of the cylinder. In the embodiments of the present invention, when the eccentric block rotates, it drives the second bracket to swing and vibrate in a rotary manner. The design of the cylinder and the circular first hollow groove enables the second bracket to swing and vibrate in a rotary manner relative to the third bracket, further driving the test tube to swing and vibrate in a rotary manner.

[0044] In one embodiment, a concave platform is provided on the side of the second bracket, and the second hollow groove is provided on the concave platform; the flexible column includes an upper column head and a column body, the upper column head is arranged on the surface of the concave platform, and the column body is arranged in the second hollow groove. The cross-sections of the upper column head of the flexible body and the second hollow groove are both circular structures, the column body is a cylindrical structure, the diameter of the cross-section of the circular structure of the upper column head of the flexible body is larger than the diameter of the cylindrical structure and the diameter of the cross-section of the circular structure of the second hollow groove, and the flexible body is made of a flexible material, such as rubber or silica gel material, or can also be a spring, so that the second bracket can swing relative to the third bracket and the first bracket.

[0045] In one embodiment, the flexible column includes a lower column head, a connecting head is arranged below the lower column head, a connecting hole is arranged on the first bracket, and the connecting head penetrates through the connecting hole to fix the flexible column on the first bracket. And the lower column head of the flexible body is a circular structure, and the diameter of the cross-section of the circular structure of the lower column head of the flexible body is larger than the diameter of the cylindrical structure and the diameter of the cross-section of the circular structure of the second hollow groove.

[0046] In one embodiment, a third hollow groove is formed on the side of the second bracket, and the third hollow groove is an arc-shaped structure with one side open; the number of the support rods is two, a part of one support rod is arranged in the first hollow groove, and a part of the other support rod is arranged in the third hollow groove, wherein a part of the other support rod is a cylindrical structure, so that the second bracket can perform a rotary swing and vibration relative to the third bracket and the first bracket.

[0047] In one embodiment, the test tube bin includes a hollow shaft sleeve, the hollow shaft sleeve is arranged on the top of the third bracket, the third bracket is provided with a through hole, the hollow shaft sleeve and the through hole are coaxially arranged, and the through part of the hollow shaft sleeve and the through hole forms a test tube accommodation space. When the embodiment of the present invention is implemented, the test tube tray holds the test tube, and the test tube accommodation space is used to accommodate the test tube to restrict the movement position of the test tube, so as to facilitate fixing the test tube and allowing the test tube to perform a rotary swing.

[0048] According to a second aspect, another embodiment of the present invention provides a blood cell analysis device, which includes a blood sample automatic mixing device described above, the blood cell analysis device further includes an automatic feeding device, the automatic feeding device includes a base and a transmission component, a second driving unit is fixed on the base, the transmission component is movably arranged on the base, the transmission component is connected to the main body, the second driving unit drives the transmission component to move relative to the base, and the transmission component drives the main body to move so as to move the test tube bin to a preparation position for receiving a blood sample collection test tube.

[0049] A blood cell analysis device according to an embodiment of the present invention includes an automatic feeding device and an automatic blood sample mixing device. First, the automatic feeding device includes a base and a transmission component. The second driving unit drives the transmission component to move, and the movement of the transmission component is used to drive the movement of the main body. Since the test tube bin is arranged on the main body, the test tube bin can be moved to the preparation position for receiving the blood sample collection test tube, thereby realizing the automatic feeding of the blood sample collection tube. Secondly, under the drive of the first driving unit, the eccentric block fixed to the output shaft end of the first driving unit rotates around the axis of the first driving unit. Since the vibration module fixing the first driving unit is connected and fixed above the main body through a flexible module, and the rotation axis hole of the eccentric block is not at its center of gravity, the rotation of the eccentric block drives the vibration module to swing and vibrate in a rotary manner. Since the blood sample collection test tube containing the sample to be mixed is arranged on the test tube tray of the main body, the swing and vibration of the vibration module will drive the test tube on the test tube tray to swing and vibrate in a rotary manner, so as to achieve the purpose of automatically mixing the sample, without manual handling, saving labor and time costs, and improving the working efficiency of mixing trace blood samples.

[0050] Further, the second driving unit is preferably a motor. In one embodiment, the device further includes a base and a transmission component. A second motor is fixed on the base. The second motor is electrically connected to the controller and is controlled by the controller. The transmission component is movably arranged on the base. The transmission component is connected to the first bracket. The second motor drives the transmission component to move relative to the base. The transmission component drives the first bracket and the third bracket to move to move the test tube bin to the preparation position for receiving the test tube to be mixed. The preparation position is as Figure 2 shown.

[0051] In one embodiment, the transmission component includes a sliding block, a sliding guide rail, a fixed block, a moving push plate, and a sliding screw nut mechanism. The sliding guide rail is fixed on the base, and the slider is arranged in the sliding guide rail; the sliding screw nut mechanism is respectively connected to the second motor and the moving push plate; the fixed block is respectively fixedly connected to the first bracket of the main body and the slider; the sliding guide rail passes through the opening in the middle of the moving push plate, and the moving push plate abuts against the fixed block. The moving push plate can be fixedly connected or not fixedly connected to the fixed block. The moving push plate pushes the fixed block and the slider to move under the action of the sliding screw nut mechanism. The slider moves along the sliding guide rail to guide the moving direction of the fixed block. Here, the slider and the sliding guide rail play a guiding role, so that the mixing device can be fed to the target position. Among them, the sliding screw nut mechanism is a propulsion mechanism well known to those skilled in the art, so the specific structure thereof will not be described here.

[0052] In one embodiment, an optical coupler shielding piece is fixed on the movable push plate, and a detection optical coupler is arranged on the base. The detection optical coupler and the optical coupler shielding piece cooperate to detect the moving position of the movable push plate. Specifically, when the movable push plate advances, the optical coupler shielding piece also advances therewith. When the light emitted by the detection optical coupler is blocked by the optical coupler shielding piece, it is determined that the movable push plate has advanced to the target position. At this time, the controller controls the second motor to stop rotating, and the movable push plate stops advancing.

[0053] Preferably, the second motor is a linear motor, and the blood sample automatic mixing device performs a moving feed in a horizontal feed manner. Specifically, in the embodiment of the present invention, the blood sample automatic mixing device starts from its ready position and first performs a horizontal feed driven by the linear motor. The sliding screw nut mechanism of the linear motor drives the movable push plate, the optical coupler shielding piece, and the fixing block to horizontally feed towards the test tube rack to a suitable position, and all the relevant components and parts associated and installed on the fixing block are fed synchronously, including the first bracket, the second bracket, and the third bracket and the components and parts installed thereon; the suitable position to be fed is that the center of the test tube bin fixed on the third horizontal bracket and the center of the lifted test tube are coaxial, as Figure 2 shown. The test tube gripper and the micro tip blood collection test tube grabbed thereby first perform a descending action, and the descending height is such that the bottom of the test tube touches or approaches the rubber test tube holder with an inner concave surface fixed on the second horizontal bracket; then the test tube gripper performs a horizontal feed and moves in a direction away from the test tube rack to the horizontal ready position, so that the test tube gripper is completely separated from the clamped test tube. Thus, the preparation for performing the blood sample mixing operation is completed, and then the specific mixing operation as described above can be carried out. For details, refer to the foregoing part, and details are not described herein again.

[0054] Referring to the specific embodiments, although the present invention has been described in the specification and drawings, it should be understood that without departing from the scope of the present invention defined in the claims, those skilled in the art can make various changes and various equivalents can replace many of the elements. Moreover, the combinations and collocations of the technical features, elements, and / or functions among the specific embodiments herein are clear and definite. Therefore, according to the disclosed content, those skilled in the art can understand that the technical features, elements, and / or functions in the embodiments can be combined into another specific embodiment as appropriate, unless otherwise described above. In addition, according to the teachings of the present invention, many changes can be made to adapt to special circumstances or materials without departing from the essence of the present invention. Therefore, the present invention is not limited to the individual specific embodiments illustrated in the drawings and the specific embodiments described in the specification as the best embodiments currently contemplated for implementing the present invention, and the present invention is intended to include all embodiments falling within the scope of the above specification and the appended claims.

Claims

1. An automatic blood sample mixing device, characterized in that, the automatic blood sample mixing device includes a first bracket, a first driving unit, an eccentric block, a flexible module, a second bracket and a third bracket. The second bracket is fixedly connected above the first bracket through the flexible module. The first driving unit is arranged on the second bracket, and the eccentric block is fixed at the output shaft end of the first driving unit. Driven by the first driving unit, the eccentric block rotates around the axis of the first driving unit, driving the second bracket to perform a rotary swing and vibration relative to the first bracket, and further driving the blood sample collection test tube supported on the second bracket to synchronously perform a rotary swing and vibration. A test tube bin is arranged on the third bracket, and a test tube tray is arranged on the second bracket, which is used to abut against the bottom of the blood sample collection test tube to accommodate the blood sample collection test tube in the test tube bin. The bottom of the blood sample collection test tube generates a rotary swing and vibration relative to the third bracket along with the second bracket, and the test tube bin is relatively stationary to restrict the body of the blood sample collection test tube, and the blood sample collection test tube will be partially restricted in the test tube bin, so that the bottom of the blood sample collection test tube swings relatively greatly; wherein, the test tube tray is made of a flexible material.

2. The automatic blood sample mixing device according to claim 1, characterized in that, the automatic blood sample mixing device further includes a support rod, and the first bracket and the third bracket are connected through the support rod.

3. The automatic blood sample mixing device according to claim 1, characterized in that, the test tube tray is provided with a concave curved surface, and the concave curved surface is used to abut against the bottom of the blood sample collection test tube to accommodate the blood sample collection test tube in the test tube bin.

4. The automatic blood sample mixing device according to claim 2, characterized in that, a first hollow groove and a second hollow groove are arranged on the second bracket, a part of the support rod is arranged in the first hollow groove, the flexible module is a flexible column, and a part of the flexible column is located in the second hollow groove.

5. The automatic blood sample mixing device according to claim 4, characterized in that, a third hollow groove is opened on the side part of the second bracket, and the third hollow groove is a circular arc structure with one side open; the number of the support rods is two, a part of one support rod is arranged in the first hollow groove, and a part of the other support rod is arranged in the third hollow groove.

6. The automatic blood sample mixing device according to claim 5, characterized in that, the test tube bin includes a hollow shaft sleeve, the hollow shaft sleeve is arranged on the top of the third bracket, a through hole is opened on the third bracket corresponding to the position of the hollow shaft sleeve, and the hollow shaft sleeve and the through hole are used to accommodate the blood sample collection test tube to restrict the moving position of the blood sample collection test tube.

7. The automatic blood sample mixing device according to claim 4, characterized in that, the flexible column is made of rubber or silica gel material, or is a spring.

8. The automatic blood sample mixing device according to claim 4, characterized in that, A concave platform is provided on the side of the second bracket, and the second hollow groove is provided on the concave platform. The flexible column includes an upper column head and a column body. The upper column head is arranged on the surface of the concave platform, and the column body is arranged in the second hollow groove. The cross-section of the upper column head is a circular structure, the column body is a cylindrical structure, and the diameter of the cross-section of the circular structure of the upper column head is greater than the diameter of the cylindrical structure of the column body.

9. An automatic blood sample mixing device according to claim 4, wherein, the flexible column includes a lower column head, a connector is arranged below the lower column head, a connection hole is arranged on the first bracket, and the connector passes through the connection hole to fix the flexible column on the first bracket.

10. A blood cell analysis device, which includes an automatic blood sample mixing device according to any one of claims 1-9, wherein, the blood cell analysis device further includes an automatic feeding device, the automatic feeding device includes a base and a transmission component, a second driving unit is fixed on the base, the transmission component is movably arranged on the base, the blood sample automatic mixing device includes a first bracket, the transmission component is connected to the first bracket, the second driving unit drives the transmission component to move relative to the base, and the transmission component drives the first bracket to move to move the test tube rack to a preparation position for receiving a test tube for collecting a blood sample to be mixed.

11. A blood cell analysis device according to claim 10, wherein, the transmission component includes a sliding block, a sliding guide rail, a fixed block, a moving push plate and a sliding screw nut mechanism. The sliding guide rail is fixed on the base, and the sliding block is arranged in the sliding guide rail; the sliding screw nut mechanism is respectively connected to the second driving unit and the moving push plate; the fixed block is respectively connected to the first bracket and the sliding block, and the moving push plate pushes the fixed block and the sliding block to move under the action of the sliding screw nut mechanism, and the sliding block moves along the sliding guide rail to guide the moving direction of the fixed block.

12. A blood cell analysis device according to claim 11, wherein, a light shield opto-coupler piece is fixed on the moving push plate, a detection opto-coupler is arranged on the base, and the detection opto-coupler and the light shield opto-coupler piece cooperate to detect the moving position of the moving push plate.

13. A blood cell analysis device according to claim 10, wherein, the blood cell analysis device further includes a test tube clamping jaw. The test tube clamping jaw is used to first perform a descending action together with the collected micro peripheral blood sample collection test tube. The descending height is that the bottom of the blood sample collection test tube touches or approaches a rubber test tube tray with an inner concave surface fixed on the second bracket. Then the test tube clamping jaw performs a horizontal feed and moves in a direction away from the test tube rack to a horizontal ready position, so that the test tube clamping jaw is completely separated from the clamped blood sample collection test tube; Wherein, the second bracket of the blood sample automatic mixing device is located between the first bracket and the third bracket; the eccentric block of the blood sample automatic mixing device is arranged on the first bracket.

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