An adjustable operating table suitable for brain stereotaxic instrument for mice and rats
By designing an adjustable operating table suitable for brain stereolocalizers of large and small mice, the problems of large and small manpower consumption, troublesome operation, unstable fixation and inconvenient tail blood retrieval in the existing technology are solved, and the effects of single-person operation, strong flexibility, accurate positioning and convenient blood retrieval are achieved.
Patent Information
- Application Number
- CN201911115244.3
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2019-11-14
- Publication Date
- 2025-03-25
- Estimated Expiration
- 2039-11-14
AI Technical Summary
The existing large and mouse brain stereolocalizers have problems such as high manpower consumption, troublesome operation, instability in fixing and operation, and inconvenient tail blood extraction.
An adjustable operating table suitable for a large and small mouse brain stereotactic meter is designed, including a first operating table, a second operating table, a bottom plate, a first lifting mechanism and a second lifting mechanism. The height adjustment is achieved through the lifting mechanism, and the torso and head fixing grooves, limb restraint belts and a tail fixing frame are provided to enhance operation flexibility and stability.
It realizes the positioning task of a single-person operation, saves manpower, improves the flexibility and accuracy of the operation, avoids the looseness of animals and the movement of the tail during the experiment, and facilitates blood extraction operation.
Smart Images

Figure CN110680553B_ABST
Abstract
Description
Technical Field
[0001] The invention relates to the technical field of medical research and medical equipment, and in particular to an adjustable operating table suitable for a brain stereotaxic instrument for mice and rats. Background Art
[0002] Stereotaxic apparatus, also known as brain fixation device, uses a three-dimensional coordinate system defined by signs on the outside of the skull or other reference points to determine the location of certain subcortical neural structures, so as to conduct targeted stimulation, destruction, drug injection, and potential guidance research under non-direct exposure. Animal brain stereotaxic apparatus is an important research device in the fields of neuroanatomy, neurophysiology, neuropharmacology, and neurosurgery. It is used for targeted injection, stimulation, destruction, and potential guidance of neural structures. It can be used to establish animal models of cerebral hemorrhage, Parkinson's disease, epilepsy, brain tumors, learning and memory, brain neural stem cell transplantation, cerebral ischemia, and other studies.
[0003] At present, commonly used stereotaxic instruments for rats and mice generally have incisor hooks and ear bars on both sides. The incisors of rats and mice are fixed on the incisor hooks, and the ear bars on both sides are aligned with the ear canals of rats and mice. The heads of rats and mice are fixed using the three-point positioning principle to facilitate subsequent research. However, there are the following shortcomings when using stereotaxic instruments to position rats and mice:
[0004] (1) When fixing rats or mice, two people are required to work together, one person holds the rat or mouse to adjust the height and position, and the other person adjusts the ear bar to align it with the ear canal of the rat or mouse. This operation is cumbersome and consumes unnecessary manpower.
[0005] (2) The current fixation method only fixes the ears and mouth, and the whole body is not fixed or the body is suspended in the air, which may cause the fixation to loosen during the experiment and affect the experimental process;
[0006] (3) When drawing blood from the tail of rats or mice, although the rats or mice are under anesthesia, their tails are tough and easily moved, making it inconvenient to draw blood. Summary of the invention
[0007] The purpose of the present invention is to solve the shortcomings of the prior art and to propose an adjustable operating table suitable for a stereotaxic instrument for the brains of mice and rats, which saves manpower and is convenient for operation.
[0008] To achieve the above object, the present invention adopts the following technical solutions:
[0009] An adjustable operating table suitable for a rat / mice brain stereotaxic instrument comprises a first operating table, a second operating table, a bottom plate, a first lifting mechanism and a second lifting mechanism; the first operating table and the second operating table are respectively arranged above the bottom plate, the first lifting mechanism is connected between the first operating table and the bottom plate, and the second lifting mechanism is connected between the second operating table and the bottom plate.
[0010] The first lifting mechanism includes a first active rod, a first driven rod and a first adjusting knob. The middle part of the first active rod is hinged to the middle part of the first driven rod. The first active rod and the first driven rod are in an X shape. The upper end of the first active rod is hinged to the side of the first operating table, the lower end of the first active rod is hinged to the side of the bottom plate, and the first adjusting knob is fixed to the outer side of the lower end of the first active rod. The side of the first operating table is provided with a first sliding groove, and the side of the bottom plate is correspondingly provided with a second sliding groove. The upper end of the first driven rod is embedded in the first sliding groove, and the lower end of the first driven rod is embedded in the second sliding groove.
[0011] The width direction of the bottom plate is taken as the X direction, the length direction of the bottom plate is taken as the Y direction, the direction perpendicular to the X direction and the Y direction is taken as the Z direction, and the extension directions of the first slide groove and the second slide groove are parallel to the Y direction.
[0012] Preferably, the second lifting mechanism includes a second active rod, a second driven rod and a second adjusting knob, the middle part of the second active rod is hinged to the middle part of the second driven rod, the second active rod and the second driven rod are X-shaped, the upper end of the second active rod is hinged to the side of the second operating table, the lower end of the second active rod is hinged to the side of the bottom plate, and the second adjusting knob is fixed to the outer side of the lower end of the second active rod; the side of the second operating table is provided with a third slide groove, the side of the bottom plate is correspondingly provided with a fourth slide groove, the upper end of the second driven rod is correspondingly embedded in the third slide groove, and the lower end of the second driven rod is correspondingly embedded in the fourth slide groove.
[0013] Preferably, it includes a longitudinal adjustment mechanism, which includes a first base, the first base is parallel to the bottom plate, a first guide rail is provided on the first base along the Y direction, a first slider is provided on the first guide rail, the top surface of the first slider is fixedly connected to the bottom surface of the bottom plate, and a first adjustment rod is connected to the side of the first slider, and the first adjustment rod is arranged along the X direction.
[0014] Preferably, it includes a lateral adjustment mechanism, which includes a second base, the second base is parallel to the bottom plate, the second base is provided with a second guide rail along the X direction, the second guide rail is provided with a second slider, the top surface of the second slider is fixedly connected to the bottom surface of the first base, the side of the second slider is connected to a second adjustment rod, and the second adjustment rod is arranged along the Y direction.
[0015] Preferably, the bottom surface of the second base is provided with an anti-slip groove.
[0016] Preferably, a torso fixing slot is provided on the first operating platform, a head fixing slot is provided on the second operating platform, and limb restraint belts and a torso restraint belt are provided on the first operating platform, and two ends of the torso restraint belt are respectively connected to two sides of the torso fixing slot.
[0017] Preferably, a tail fixing frame is provided on a side of the first operating platform away from the second operating platform, the tail fixing frame is trumpet-shaped, and the inner end opening of the tail fixing frame is large and the outer end opening is small.
[0018] Preferably, the tail fixing frame comprises an upper half and a lower half, the upper half is hinged to the lower half on one side, and the other side is detachably connected to the lower half by a fastening bolt.
[0019] Preferably, a first embedded block is provided at the upper end of the first driven rod, and the structure of the first embedded block matches the structure of the first slide groove; a second embedded block is provided at the lower end of the first driven rod, and the structure of the second embedded block matches the structure of the second slide groove.
[0020] Preferably, a third embedded block is provided at the upper end of the second driven rod, and the structure of the third embedded block matches the structure of the third slide groove; a fourth embedded block is provided at the lower end of the second driven rod, and the structure of the fourth embedded block matches the structure of the fourth slide groove.
[0021] Compared with the prior art, the present invention has the following beneficial effects:
[0022] (1) During the experiment, the trunk of the anesthetized rat or mouse is placed on the first operating table and the head is placed on the second operating table. The first operating table is height-adjusted by the first lifting mechanism, and the second operating table is height-adjusted by the second lifting mechanism. Only one person is required to complete the positioning operation, thus saving manpower.
[0023] (2) The heights of the first operating table and the second operating table can be adjusted independently, that is, the position of the torso or head of the rat or mouse can be adjusted independently within the allowed range, and the adjustment flexibility is strong;
[0024] (3) The first operating table is provided with a trunk fixing slot, limb restraint belts and a trunk restraint belt, and the second operating table is provided with a head fixing slot, which can fix the trunk and head of the rat or mouse respectively to prevent the rat or mouse from loosening during the experiment, which is conducive to the smooth progress of the experimental process;
[0025] (4) A longitudinal adjustment mechanism and a lateral adjustment mechanism are also provided under the bottom plate to facilitate adjustment of the horizontal positions of the first operating platform and the second operating platform. Only one person is required to operate the system, making the positioning operation more accurate and saving manpower.
[0026] (5) A tail fixing frame with a large inner opening and a small outer opening is set on the first operating table. The tail of rats and mice can be effectively fixed by the tail fixing frame to prevent the tail from moving around, thereby facilitating the blood sampling operation during the experiment. BRIEF DESCRIPTION OF THE DRAWINGS
[0027] Figure 1 A stereogram of an adjustable operating table suitable for a stereotaxic apparatus for the brains of mice and rats according to Example 1 of the present invention;
[0028] Figure 2 This is a split stereogram of an adjustable operating table suitable for a stereotaxic apparatus for the brains of mice and rats according to embodiment 2 of the present invention;
[0029] Figure 3 A three-dimensional diagram of a first lifting mechanism in an adjustable operating table suitable for a stereotaxic apparatus for the brains of mice and rats according to Example 1 of the present invention;
[0030] Figure 4 A three-dimensional diagram of a second lifting mechanism in an adjustable operating table suitable for a brain stereotaxic instrument for mice and rats according to Example 1 of the present invention;
[0031] Figure 5 A side view of a first driven rod in an adjustable operating table suitable for a stereotaxic apparatus for mice and rats according to embodiment 1 of the present invention;
[0032] Figure 6 A side view of a second driven rod in an adjustable operating table suitable for a stereotaxic apparatus for mice and rats according to embodiment 1 of the present invention;
[0033] Figure 7 This is a stereoscopic view of a tail fixing frame in an adjustable operating table of a brain stereotaxic instrument suitable for mice and rats according to Example 1 of the present invention.
[0034] Among them, 10-first operating platform, 11-first slide, 12-trunk fixing slot, 13-limb restraint belt, 14-trunk restraint belt, 15-tail fixing frame, 151-upper half, 152-lower half, 153-fastening bolt, 20-second operating platform, 21-third slide, 22-head fixing slot, 30-bottom plate, 31-second slide, 32-fourth slide, 40-first lifting mechanism, 4-first active rod, 42-first driven rod, 421-first embedded block, 422-second embedded block, 4 3-first adjusting knob, 44-first cross bar, 50-second lifting mechanism, 51-second active rod, 52-second driven rod, 521-third embedded block, 522-fourth embedded block, 53-second adjusting knob, 54-second cross bar, 60-longitudinal adjustment mechanism, 61-first base, 62-first guide rail, 63-first slider, 64-first adjusting rod, 70-lateral adjustment mechanism, 71-second base, 711-anti-slip groove, 72-second guide rail, 73-second slider, 74-second adjusting rod. DETAILED DESCRIPTION
[0035] In order to provide a further understanding of the purpose, structure, features, and functions of the present invention, the following detailed description is given in conjunction with the embodiments.
[0036] Please refer to Figures 1 to 7 , Figure 1 A stereogram of an adjustable operating table suitable for a stereotaxic apparatus for the brains of mice and rats according to Example 1 of the present invention; Figure 2 This is a split stereogram of an adjustable operating table suitable for a stereotaxic apparatus for the brains of mice and rats according to embodiment 2 of the present invention; Figure 3 A three-dimensional diagram of a first lifting mechanism in an adjustable operating table suitable for a stereotaxic apparatus for the brains of mice and rats according to Example 1 of the present invention; Figure 4 A three-dimensional diagram of a second lifting mechanism in an adjustable operating table suitable for a brain stereotaxic instrument for mice and rats according to Example 1 of the present invention; Figure 5 A side view of a first driven rod in an adjustable operating table suitable for a stereotaxic apparatus for mice and rats according to embodiment 1 of the present invention; Figure 6 A side view of a second driven rod in an adjustable operating table suitable for a stereotaxic apparatus for mice and rats according to embodiment 1 of the present invention; Figure 7 This is a stereoscopic view of a tail fixing frame in an adjustable operating table of a brain stereotaxic instrument suitable for mice and rats according to Example 1 of the present invention.
[0037] See also Figure 1, Embodiment 1 of the present invention is an adjustable operating table suitable for a stereotaxic instrument for rats and mice, comprising a first operating table 10, a second operating table 20, a bottom plate 30, a first lifting mechanism 40 and a second lifting mechanism 50; the first operating table 10 and the second operating table 20 are respectively arranged above the bottom plate 30, the first lifting mechanism 40 is connected between the first operating table 10 and the bottom plate 30, and the second lifting mechanism 50 is connected between the second operating table 20 and the bottom plate 30. During the experiment, the trunk of the anesthetized rat or mouse is placed on the first operating table 10 and the head is placed on the second operating table 20, the first lifting mechanism 40 is used to adjust the height of the first operating table 10, and the second lifting mechanism 50 is used to adjust the height of the second operating table 20, and only one person is needed to complete the positioning operation, saving manpower; the height of the first operating table 10 and the second operating table 20 can be adjusted independently, that is, the position of the trunk or head of the rat or mouse can be independently adjusted within the allowed range, and the adjustment flexibility is strong.
[0038] Please refer to Figure 1 , Figure 3 and Figure 5 The first lifting mechanism 40 includes a first active rod 41, a first driven rod 42 and a first adjusting knob 43. The middle part of the first active rod 41 is hinged to the middle part of the first driven rod 42. The first active rod 41 and the first driven rod 42 are in an X shape. The upper end of the first active rod 41 is hinged to the side of the first operating table 10, and the lower end of the first active rod 41 is hinged to the side of the bottom plate 30. The first adjusting knob 43 is fixed to the outer side of the lower end of the first active rod 41; a first slide groove 11 is provided on the side of the first operating table 10, and a second slide groove 31 is correspondingly provided on the side of the bottom plate 30. The upper end of the first driven rod 42 is embedded in the first slide groove 11, and the lower end of the first driven rod 42 is embedded in the second slide groove 31. The upper end of the first driven rod 42 can slide in the first slide groove 11, and the lower end of the first driven rod 42 can slide in the second slide groove 31. The height adjustment process of the first operating platform 10 is as follows: when the first adjusting knob 43 is rotated, the first active rod 41 rotates, and the angle between the first active rod 41 and the base plate 30 changes. Since the first driven rod 42 is hinged to the first active rod 41, the upper end of the first driven rod 42 can slide in the first slide groove 11, and the lower end of the first driven rod 42 can slide in the second slide groove 31, so the first driven rod 42 also rotates at the same time, and the angle between the first driven rod 42 and the base plate 30 changes, thereby changing the height between the first operating platform 10 and the base plate 30 to achieve the purpose of height adjustment; in Example 1 of the present invention, rotating the first adjusting knob 43 clockwise can lower the height of the first operating platform 10, and rotating the first adjusting knob 43 counterclockwise can increase the height of the first operating platform 10.
[0039] The width direction of the bottom plate 30 is the X direction, the length direction of the bottom plate 30 is the Y direction, and the direction perpendicular to the X direction and the Y direction is the Z direction. The extension directions of the first slide groove 11 and the second slide groove 31 are parallel to the Y direction.
[0040] Preferably, please refer to Figure 1 , Figure 4 and Figure 6 The second lifting mechanism 50 includes a second active rod 51, a second driven rod 52 and a second adjusting knob 53. The middle part of the second active rod 51 is hinged to the middle part of the second driven rod 52, and the second active rod 51 and the second driven rod 52 are X-shaped. The upper end of the second active rod 51 is hinged to the side of the second operating table 20, and the lower end of the second active rod 51 is hinged to the side of the bottom plate 30. The second adjusting knob 53 is fixed to the outer side of the lower end of the second active rod 51; a third slide groove 21 is provided on the side of the second operating table 20, and a fourth slide groove 32 is correspondingly provided on the side of the bottom plate 30. The upper end of the second driven rod 52 is correspondingly embedded in the third slide groove 21, and the lower end of the second driven rod 52 is correspondingly embedded in the fourth slide groove 32. The upper end of the second driven rod 52 can slide in the third slide groove 21, and the lower end of the second driven rod 52 can slide in the fourth slide groove 32. The height adjustment process of the second operating platform 20 is similar to the height adjustment process of the first operating platform 10: when the second adjusting knob 53 is rotated, the second active rod 51 rotates, and the angle between the second active rod 51 and the base plate 30 changes. Since the second driven rod 52 is hinged to the second active rod 51, the upper end of the second driven rod 52 can slide in the third slide groove 21, and the lower end of the second driven rod 52 can slide in the fourth slide groove 32, so the second driven rod 52 also rotates accordingly, and the angle between the second driven rod 52 and the base plate 30 changes, thereby changing the height between the second operating platform 20 and the base plate 30 to achieve the purpose of height adjustment; in Example 1 of the present invention, rotating the second adjusting knob 53 clockwise can lower the height of the second operating platform 20, and rotating the second adjusting knob 53 counterclockwise can increase the height of the second operating platform 20.
[0041] See also Figure 3 In a preferred embodiment of the present invention, a first active rod 41 and a first driven rod 42 are provided on both sides of the first operating platform 10, and a first cross bar 44 is hinged in the middle, which can enhance the stability of the first operating platform 10; see Figure 4 In a preferred embodiment of the present invention, a second active rod 51 and a second driven rod 52 are provided on both sides of the second operating platform 20, and a second cross bar 54 is hinged in the middle, which can enhance the stability of the second operating platform 20.
[0042] Preferably, see Figure 2The adjustable operating table of Example 2 of the present invention further includes a longitudinal adjustment mechanism 60, which includes a first base 61, which is parallel to the bottom plate 30, and a first guide rail 62 is provided on the first base 61 along the Y direction, and a first slider 63 is provided on the first guide rail 62, and the top surface of the first slider 63 is fixedly connected to the bottom surface of the bottom plate 30, and the side of the first slider 63 is connected to a first adjustment rod 64, which is arranged along the X direction. The present invention uses the longitudinal adjustment mechanism 60 to adjust the Y-direction position of the first operating table 10 and the second operating table 20, and when the first adjustment rod 64 is pulled, the first slider 63 slides along the first guide rail 62.
[0043] Preferably, see Figure 2 The adjustable operating table of Example 2 of the present invention further includes a transverse adjustment mechanism 70, which includes a second base 71, the second base 71 is parallel to the bottom plate 30, a second guide rail 72 is provided on the second base 71 along the X direction, a second slider 73 is provided on the second guide rail 72, the top surface of the second slider 73 is fixedly connected to the bottom surface of the first base 61, and a second adjustment rod 74 is connected to the side of the second slider 73, and the second adjustment rod 74 is provided along the Y direction. The present invention uses the transverse adjustment mechanism 70 to adjust the X-direction position of the first operating table 10 and the second operating table 20. When the second adjustment rod 74 is pulled, the second slider 73 slides along the second guide rail 72.
[0044] Preferably, see Figure 2 The bottom surface of the second base 71 is provided with an anti-skid groove 711, which can increase the friction between the bottom surface of the second base 71 and the experimental table, ensure the stability of the present invention, and prevent it from sliding.
[0045] Preferably, see Figure 1 or Figure 2 The first operating platform 10 is provided with a trunk fixing groove 12, the second operating platform 20 is provided with a head fixing groove 22, the first operating platform 10 is provided with a limb restraint belt 13 and a trunk restraint belt 14, and the two ends of the trunk restraint belt 14 are respectively connected to the two sides of the trunk fixing groove 12. During the experiment, the trunk of the anesthetized rat or mouse is placed in the trunk fixing groove 12, and the head is placed in the head fixing groove 22. The limbs of the rat or mouse are fixed by the limb restraint belt 13, and the trunk of the rat or mouse is fixed by the trunk restraint belt 14 to prevent the rat or mouse from sliding during the experiment and affecting the experimental results. Preferably, one end of the trunk restraint belt 14 is fixedly connected to the first operating platform 10, and the other end is detachably connected to the first operating platform 10 by Velcro or the like.
[0046] Preferably, please refer to Figure 1 and Figure 7In a preferred embodiment of the present invention, a tail fixing frame 15 is provided on the side of the first operating platform 10 away from the second operating platform 20. The tail fixing frame 15 is trumpet-shaped, and the inner end opening of the tail fixing frame 15 is large and the outer end opening is small. The tail fixing frame 15 can fix the tail of the rat or mouse to prevent it from moving around due to toughness, making it convenient for researchers to perform tail blood sampling operations. Preferably, the tail fixing frame 15 includes an upper half 151 and a lower half 152. The upper half 151 is hinged to the lower half 152 on one side, and the other side is detachably connected by a fastening bolt 153. The lower half 152 of the tail fixing frame 15 is fixed on the first operating table 10, and the upper half 151 can rotate around the hinge between it and the lower half 152. When fixing a rat or a mouse, the upper half 151 is opened, and the tail of the rat or the mouse is placed inside the lower half 152. Then the upper half 151 is covered, and the upper half 151 and the lower half 152 are fixedly connected using the fastening bolts 153, so that the tail of the rat or the mouse can be effectively fixed, which is convenient for subsequent operations.
[0047] Preferably, see Figure 3 or Figure 5 The upper end of the first driven rod 42 is provided with a first embedded block 421, the structure of the first embedded block 421 matches the structure of the first slide groove 11, the first embedded block 421 is embedded in the first slide groove 11 and can slide in the first slide groove 11; the lower end of the first driven rod 42 is provided with a second embedded block 422, the structure of the second embedded block 422 matches the structure of the second slide groove 31, the second embedded block 422 is embedded in the second slide groove 31 and can slide in the second slide groove 31; when the first active rod 41 is rotated by using the first adjusting knob 43, Since the first driven rod 42 is hinged to the first active rod 41, the first driven rod 42 can be driven to rotate, the first embedded block 421 slides in the first slide groove 11, and the second embedded block 422 slides in the second slide groove 31, thereby changing the distance between the first operating platform 10 and the bottom plate 30, thereby achieving the purpose of adjusting the height of the first operating platform 10; in Example 1, the height of the first operating platform 10 can be lowered by rotating the first adjusting knob 43 clockwise, and the height of the first operating platform 10 can be increased by rotating the first adjusting knob 43 counterclockwise.
[0048] See also Figure 4 or Figure 6The upper end of the second driven rod 52 is provided with a third embedded block 521, the structure of the third embedded block 521 matches the structure of the third slide groove 21, and the third embedded block 521 is embedded in the third slide groove 21 and can slide in the third slide groove 21; the lower end of the second driven rod 52 is provided with a fourth embedded block 522, the structure of the fourth embedded block 522 matches the structure of the fourth slide groove 32, and the fourth embedded block 522 is embedded in the fourth slide groove 32 and can slide in the fourth slide groove 32; when the second active rod 51 is rotated by the second adjusting knob 53 Since the second driven rod 52 is hinged to the second active rod 51, the second driven rod 52 can be driven to rotate, the third embedded block 521 slides in the third slide groove 21, and the fourth embedded block 522 slides in the fourth slide groove 32, thereby changing the distance between the second operating platform 20 and the bottom plate 30, thereby achieving the purpose of adjusting the height of the second operating platform 20; in Example 1, the height of the second operating platform 20 can be lowered by rotating the second adjusting knob 53 clockwise, and the height of the second operating platform 20 can be increased by rotating the second adjusting knob 53 counterclockwise.
[0049] In summary, the present invention provides an adjustable operating table suitable for a stereotaxic instrument for the brain of large and small mice. During the experiment, the trunk of the anesthetized rat or mouse is placed on the first operating table 10 and the head is placed on the second operating table 20. The first lifting mechanism 40 is used to adjust the height of the first operating table 10, and the second lifting mechanism 50 is used to adjust the height of the second operating table 20. Only one person is needed to complete the positioning operation, saving manpower; the height of the first operating table 10 and the second operating table 20 can be adjusted independently, that is, the position of the trunk or head of the rat or mouse can be independently adjusted within the allowed range, and the adjustment flexibility is strong; the first operating table 10 is provided with a trunk fixing groove 12, a limb restraint belt 13 and a trunk restraint belt Belt 14, a head fixing groove 22 is provided on the second operating table 20, which can fix the trunk and head of the rat or mouse respectively, so as to prevent the rat or mouse from loosening during the experiment, which is conducive to the smooth progress of the experiment; preferably, a longitudinal adjustment mechanism 60 and a lateral adjustment mechanism 70 are also provided under the bottom plate 30, so as to facilitate the adjustment of the horizontal positions of the first operating table 10 and the second operating table 20, and only one person is required to operate it, so that the positioning operation is more accurate and manpower is saved; a tail fixing frame 15 with a small inner opening and a large outer opening is provided on the first operating table 10, and the tail of the rat or mouse is effectively fixed by the tail fixing frame 15 to prevent the tail from moving randomly, so as to facilitate the tail blood collection operation during the experiment.
[0050] The present invention has been described by the above-mentioned relevant embodiments, however, the above-mentioned embodiments are only examples for implementing the present invention. It must be pointed out that the disclosed embodiments do not limit the scope of the present invention. On the contrary, changes and modifications made without departing from the spirit and scope of the present invention are all within the scope of patent protection of the present invention.
Claims
1. An adjustable operating table suitable for a stereotaxic instrument for rats and mice, characterized in that: It includes a first operating platform, a second operating platform, a bottom plate, a first lifting mechanism and a second lifting mechanism; The first operating platform and the second operating platform are correspondingly arranged above the bottom plate, the first lifting mechanism is connected between the first operating platform and the bottom plate, and the second lifting mechanism is connected between the second operating platform and the bottom plate; a tail fixing frame is arranged on the side of the first operating platform away from the second operating platform, the tail fixing frame is trumpet-shaped, and the inner end opening of the tail fixing frame is large and the outer end opening is small; The first lifting mechanism comprises a first active rod, a first driven rod and a first adjusting knob, the middle part of the first active rod is hinged to the middle part of the first driven rod, the first active rod and the first driven rod are in an X shape, the upper end of the first active rod is hinged to the side of the first operating table, the lower end of the first active rod is hinged to the side of the bottom plate, and the first adjusting knob is fixed to the outer side of the lower end of the first active rod; the side of the first operating table is provided with a first slide groove, the side of the bottom plate is correspondingly provided with a second slide groove, the upper end of the first driven rod is embedded in the first slide groove, and the lower end of the first driven rod is embedded in the second slide groove; the first active rod and the first driven rod are provided on both sides of the first operating table, and a first cross bar is also hinged in the middle; The width direction of the bottom plate is taken as the X direction, the length direction of the bottom plate is taken as the Y direction, the direction perpendicular to the X direction and the Y direction is taken as the Z direction, and the extension directions of the first slide groove and the second slide groove are parallel to the Y direction.
2. The adjustable operating table suitable for the stereotaxic instrument for rats and mice as claimed in claim 1, characterized in that: The second lifting mechanism includes a second active rod, a second driven rod and a second adjusting knob. The middle part of the second active rod is hinged to the middle part of the second driven rod. The second active rod and the second driven rod are in an X shape. The upper end of the second active rod is hinged to the side of the second operating table, the lower end of the second active rod is hinged to the side of the bottom plate, and the second adjusting knob is fixed to the outer side of the lower end of the second active rod. The side of the second operating table is provided with a third sliding groove, and the side of the bottom plate is correspondingly provided with a fourth sliding groove. The upper end of the second driven rod is correspondingly embedded in the third sliding groove, and the lower end of the second driven rod is correspondingly embedded in the fourth sliding groove.
3. The adjustable operating table suitable for the stereotaxic instrument for rats and mice as claimed in claim 1, characterized in that: The longitudinal adjustment mechanism includes a first base, the first base is parallel to the bottom plate, a first guide rail is provided on the first base along the Y direction, a first slider is provided on the first guide rail, the top surface of the first slider is fixedly connected to the bottom surface of the bottom plate, a first adjustment rod is connected to the side of the first slider, and the first adjustment rod is provided along the X direction.
4. The adjustable operating table suitable for the stereotaxic instrument for rats and mice as claimed in claim 3, characterized in that: The invention comprises a lateral adjustment mechanism, wherein the lateral adjustment mechanism comprises a second base, the second base is parallel to the bottom plate, a second guide rail is arranged on the second base along the X direction, a second slider is arranged on the second guide rail, a top surface of the second slider is fixedly connected to a bottom surface of the first base, a side edge of the second slider is connected to a second adjustment rod, and the second adjustment rod is arranged along the Y direction.
5. The adjustable operating table suitable for the stereotaxic instrument for rats and mice as claimed in claim 4, characterized in that: The bottom surface of the second base is provided with an anti-slip groove.
6. The adjustable operating table suitable for the stereotaxic instrument for rats and mice as claimed in claim 1, characterized in that: The first operating platform is provided with a trunk fixing slot, the second operating platform is provided with a head fixing slot, and the first operating platform is provided with limb restraint belts and a trunk restraint belt, and the two ends of the trunk restraint belt are respectively connected to the two sides of the trunk fixing slot.
7. The adjustable operating table suitable for the stereotaxic instrument for rats and mice as claimed in claim 1, characterized in that: The tail fixing frame comprises an upper half and a lower half, wherein the upper half is hinged to the lower half on one side and is detachably connected to the lower half on the other side by a fastening bolt.
8. The adjustable operating table suitable for the stereotaxic instrument for rats and mice as claimed in claim 1, characterized in that: A first embedded block is disposed at the upper end of the first driven rod, and the structure of the first embedded block matches the structure of the first slide groove; a second embedded block is disposed at the lower end of the first driven rod, and the structure of the second embedded block matches the structure of the second slide groove.
9. The adjustable operating table suitable for the stereotaxic instrument for rats and mice as claimed in claim 2, characterized in that: A third embedded block is disposed at the upper end of the second driven rod, and the structure of the third embedded block matches the structure of the third slide groove; a fourth embedded block is disposed at the lower end of the second driven rod, and the structure of the fourth embedded block matches the structure of the fourth slide groove.
Citation Information
Patent Citations
Operating table for establishing rat rubrospinal tract transection animal model
CN104352286A
Adjusting platform of engineering surveying instrument
CN209055121U
Adjustable operating table suitable for rat brain stereotaxic apparatus
CN211356046U