A segment marking bracket

Abstract

The present invention provides a stent for marking segments, the stent for marking segments includes a tubular stent formed by a plurality of axially connected wavy support members and a development mark, the tubular stent includes a proximal support mechanism, a middle region support mechanism and a distal support mechanism connected in sequence; the development mark is arranged on the wavy support member connecting the proximal support mechanism and / or the distal support mechanism with the middle region support mechanism, or the development mark is arranged on the wavy support member connecting the middle region support mechanism with the proximal support mechanism and / or the distal support mechanism. The stent for marking segments provided by the present invention can accurately release the stent arranged in segments to the lesion position in the branch blood vessel by setting the development mark at the segment, and the stent arranged in segments can meet the requirements of different lesion blood vessels for different support forces.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and in particular to a segmented marking bracket. Background Art

[0002] With the rapid development of modern society, the aging of the population has intensified, people's work pressure has continued to increase, and their living habits are not healthy enough, which has led to the frequent occurrence of cardiovascular diseases in my country and has become the number one disease that endangers the health of the Chinese people. Its prevention and treatment has become the focus of attention of the medical community at home and abroad. Among them, efficient and minimally invasive interventional treatments such as implantation of vascular stents are currently the most important and effective cardiovascular disease diagnosis and treatment technologies.

[0003] For vascular stenosis or occlusive lesions, vascular stents can be implanted to support and dilate the diseased blood vessels so that blood flow in the diseased blood vessels can be restored. Generally speaking, different positions of diseased blood vessels have different requirements for the support force of the stent, and the current stents cannot meet the conditions for adapting to the different support forces required for different positions. In order to meet different support force requirements, the stent must have sufficient radial support force to offset the radial pressure exerted by the blood vessel wall. At the same time, the stent must be flexible enough in the axial direction to prevent kinking at the junction or bend of the blood vessel, which leads to a decrease in blood flow in the blood vessel.

[0004] At present, there are some stents with segmented designs, which include support sections and connecting sections. The radial support force of the support section is often greater than that of the connecting section. This segmented stent design can guarantee the radial support force of the stent and the bending flexibility of the stent to a certain extent. This segmented stent is particularly suitable for the treatment of diseased blood vessels in veins (such as iliac veins or femoral veins) located in the pelvic region of the body. The proximal ends of these veins are compressed by arteries and pelvic regions. Stents implanted in this area require greater radial support to maintain smooth blood flow in the blood vessels; due to the curved shape of the blood vessels in the middle region, the stents in this region are required to have better flexibility. Therefore, it is particularly important to design segmented stents suitable for special areas and enable the segmented stents to be accurately positioned to the most suitable blood vessel position during implantation. Summary of the invention

[0005] In view of this, the present invention provides a segmented marking stent that can be accurately guided into a branch vessel. The specific technical solution is as follows.

[0006] A segmented marking bracket, the segmented marking bracket comprises a tubular bracket formed by a plurality of axially connected wavy support members and a development mark, the tubular bracket comprises a proximal support mechanism, a middle region support mechanism and a distal support mechanism connected in sequence; the development mark is arranged on the wavy support member connecting the proximal support mechanism and / or the distal support mechanism with the middle region support mechanism, or the development mark is arranged on the wavy support member connecting the middle region support mechanism with the proximal support mechanism and / or the distal support mechanism.

[0007] Preferably, the wavy support member includes a first wavy support member, a second wavy support member and a third wavy support member; the proximal support mechanism includes a plurality of axially connected first wavy support members, the middle zone support mechanism includes a plurality of axially connected second wavy support members, and the distal support mechanism includes a plurality of axially connected third wavy support members.

[0008] Preferably, the first wave-shaped support member is composed of first support units connected end to end, the first support unit is composed of a first wave crest, a first wave trough, and a first wave rod connected between the first wave crest and the first wave trough, and the first wave crest is arranged closer to the proximal end than the first wave trough;

[0009] The second wave-shaped support member is composed of second support units connected end to end, the second support unit is composed of a second wave crest, a second wave trough, and a second wave rod connected between the second wave crest and the second wave trough, and the second wave crest is arranged closer to the proximal end than the second wave trough;

[0010] The third wave-shaped support member is composed of third support units connected end to end, and the third support unit is composed of a third wave crest, a third wave trough and a third wave rod connected between the third wave crest and the third wave trough, and the third wave crest is arranged closer to the proximal end than the third wave trough.

[0011] Preferably, the “development mark is disposed on the wavy support member connecting the proximal support mechanism and / or the distal support mechanism with the middle support mechanism” includes that the development mark is disposed on the first wavy support member connecting the proximal support mechanism with the middle support mechanism; or disposed on the third wavy support member connecting the distal support mechanism with the middle support mechanism;

[0012] The “development mark is arranged on the wavy support member connecting the middle area support mechanism with the proximal support mechanism and / or the distal support mechanism” includes that the development mark is arranged on the second wavy support member connecting the middle area support mechanism with the proximal support mechanism; or is arranged on the second wavy support member connecting the middle area support mechanism with the distal support mechanism.

[0013] Preferably, the “the development mark is arranged on the first wave-shaped support member connecting the proximal support mechanism and the middle support mechanism” includes the development mark being arranged at the first wave valley position of the proximal support mechanism closest to the middle support mechanism;

[0014] The “being arranged on the third wave-shaped support member connecting the distal support mechanism and the middle support mechanism” includes being arranged at the third wave crest position of the distal support mechanism closest to the middle support mechanism;

[0015] The “being arranged on the second wave-shaped support member connecting the middle support mechanism and the proximal support mechanism” includes being arranged at the second wave crest position of the middle support mechanism closest to the proximal support mechanism;

[0016] The “being arranged on a second wave-shaped support member connecting the middle region support mechanism and the distal end support mechanism” includes being arranged at a second wave valley position of the middle region support mechanism which is closest to the distal end support mechanism.

[0017] Preferably, the development mark is fixed on the corrugated support member by stamping, hot pressing, sewing or winding.

[0018] Preferably, the material for forming / making the development mark includes one or more of gold, platinum, platinum-tungsten, palladium, platinum-iridium, rhodium, and tantalum.

[0019] Preferably, the middle zone support mechanism and the distal support mechanism are respectively annular structures; the proximal support mechanism includes a circumferential support portion connected to the middle zone support mechanism and a directional support portion arranged at the proximal end of the circumferential support portion; the circumferential support portion is an annular structure; the directional support portion is open in the circumferential direction to form a proximal end face, and the proximal end face is a non-flush structure to form local support in the circumferential direction.

[0020] Preferably, the proximal end surface is an inclined plane, a curved surface or a wavy surface.

[0021] Preferably, the proximal end surface is an inclined plane, and an angle α between the proximal end surface and the central axis of the segmented marking bracket satisfies: 90°>α>0°.

[0022] Preferably, the directional support portion is a grid-like open-loop structure, and the number of grids decreases gradually from the distal end to the proximal end.

[0023] Preferably, the first wave crest in the first wave-shaped support member is connected to the first wave trough in the first wave-shaped support member which is axially adjacent and close to the proximal end, so that the proximal support mechanism forms a grid-like structure.

[0024] Preferably, the tubular stent further includes a connecting assembly, through which the proximal support mechanism and the middle region support mechanism, the middle region support mechanism and the distal support mechanism, or two adjacent second wavy support members in the middle region support mechanism are connected.

[0025] Preferably, the connecting assembly includes at least one connecting rod, and the “the proximal support mechanism and the middle region support mechanism are connected via the connecting assembly” includes that the first wave crest and / or the first wave trough of the first wavy support member in the proximal support mechanism and the second wave rod of the second wavy support member in the middle region support mechanism are connected via the connecting rod, or the first wave rod of the first wavy support member in the proximal support mechanism and the second wave crest and / or the second wave trough of the second wavy support member in the middle region support mechanism are connected via the connecting rod;

[0026] The “two adjacent second wavy support members in the middle region support mechanism are connected via the connecting assembly” includes the second wave crest and / or second wave trough of the second wavy support member in the middle region support mechanism being connected to the second wave rod of the adjacent second wavy support member via the connecting rod;

[0027] The “connection between the middle zone support mechanism and the distal support mechanism via the connecting assembly” includes the connection between the second wave rod of the second wavy support member in the middle zone support mechanism and the third wave peak and / or third wave trough of the third wavy support member in the distal support mechanism via the connecting rod, or the connection between the second wave peak and / or second wave trough of the second wavy support member in the middle zone support mechanism and the third wave rod of the third wavy support member in the distal support mechanism via the connecting rod.

[0028] Preferably, the same connecting assembly includes at least two connecting rods, and adjacent connecting rods are arranged in an eight-shaped or inverted eight-shaped shape.

[0029] Preferably, the projections of the axially adjacent connecting components do not overlap or partially overlap in the axial direction.

[0030] Preferably, the proximal end of the directional support portion gradually extends and expands outside the tubular stent from the distal end to the proximal end.

[0031] Preferably, the proximal end of the directional support portion extends outward from the tubular stent to expand to form an expansion portion, and an angle β between an outer contour line of the expansion portion and a central axis of the stent satisfies: 30°≥β>0°.

[0032] Preferably, the third wave crest in the third wave-shaped support member is connected to the third wave trough in the third wave-shaped support member which is axially adjacent and close to the proximal end, so that the distal support mechanism forms a grid-like structure.

[0033] Preferably, the outer diameter of the tubular stent gradually increases from the distal end to the proximal end.

[0034] Preferably, the developing mark is that the wavy support member connecting the proximal supporting mechanism and / or the distal supporting mechanism with the middle zone supporting mechanism is made of an alloy containing a developing material, or the developing mark is that the wavy support member connecting the middle zone supporting mechanism with the proximal supporting mechanism and / or the distal supporting mechanism is made of an alloy containing a developing material.

[0035] Beneficial effects of the present invention: The present invention provides a stent with segment markings. Setting development marks at the segments can accurately release the segmented stent to the lesion position in the branch blood vessel, and the segmented stent can meet the requirements of different lesion blood vessels for different supporting forces. BRIEF DESCRIPTION OF THE DRAWINGS

[0036] Figure 1-Figure 2 A schematic structural diagram of a segment marking bracket provided in the first embodiment of the present invention.

[0037] Figure 3 A schematic diagram of the unfolded structure of a segment marking bracket provided in the second embodiment of the present invention.

[0038] Figure 4 for Figure 3 A partial enlarged view of part A.

[0039] Figure 5 A schematic structural diagram of a segment marking bracket provided in the third embodiment of the present invention.

[0040] Figure 6 A schematic structural diagram of a segment marking bracket provided in the fourth embodiment of the present invention.

[0041] Figure 7 A schematic structural diagram of a segment marking bracket provided in the fifth embodiment of the present invention.

[0042] Figure 8 A schematic structural diagram of a segment marking bracket provided in the sixth embodiment of the present invention.

[0043] Fig. 9 A schematic structural diagram of a segment marking bracket provided in the seventh embodiment of the present invention.

[0044] Fig.10 A schematic structural diagram of a segment marking bracket provided in the eighth embodiment of the present invention.

[0045] Fig.11 A schematic structural diagram of a segment marking bracket provided in the ninth embodiment of the present invention.

[0046] Fig.12 A schematic structural diagram of a segment marking bracket provided in the tenth embodiment of the present invention.

[0047] Fig.13 A schematic structural diagram of a segment marking bracket provided in the eleventh embodiment of the present invention.

[0048] Fig.14 This is a schematic diagram of the effect of applying a segmented marking stent in a bifurcated blood vessel provided by the tenth embodiment of the present invention. DETAILED DESCRIPTION

[0049] The following is a preferred embodiment of the present invention. It should be noted that a person skilled in the art may make several improvements and modifications without departing from the principle of the present invention. These improvements and modifications are also considered to be within the scope of protection of the present invention.

[0050] Definition of orientation: The proximal end in the present invention refers to the end of the stent close to the heart after the stent is implanted in the blood vessel; the following structure refers to the structure of the stent after expansion. The axial direction refers to the central axis direction of the stent, and the direction perpendicular to the central axis is the radial direction. The inner side of the stent refers to the side close to the bifurcation of the bifurcated blood vessel when the stent is expanded.

[0051] See also Figure 1 The first embodiment of the present invention provides a segmented marking stent 10, which includes a tubular stent 100 formed by a plurality of wavy support members 200 connected together axially and a development mark 140. The wavy support members 200 are arranged in a wave shape.

[0052] The tubular stent 200 includes a proximal support mechanism 110, a middle support mechanism 120 and a distal support mechanism 130 connected in sequence. The three sections are used to support different positions of the diseased blood vessels. The development mark 140 is set on the wavy support member 200 where the proximal support mechanism 110 and / or the distal support mechanism 130 are connected to the middle support mechanism 120, or the development mark 140 is set on the wavy support member 200 where the middle support mechanism 120 is connected to the proximal support mechanism 110 and / or the distal support mechanism 130. It can be understood that the development mark 140 is set at the connection between the proximal support mechanism 110 and the middle support mechanism 120 and / or the distal support mechanism 130 and the middle support mechanism 120.

[0053] The present invention provides a segmented marking stent 10. The development mark 140 is set at the segment to accurately release the segmented stent to the branch vessel lesion position, improve the operation efficiency and accuracy, and the segmented stent can meet the different support force requirements of different lesions of the blood vessel. The design of the segmented marking provided by the present invention can be applied to a bare stent or a covered stent.

[0054] The segmented stent 10 of the present invention can be manufactured by laser cutting and heat setting, and the material of the stent body can be selected from stainless steel, tantalum, cobalt-based alloy, platinum, nickel-titanium alloy and new titanium alloy, and the preferred material is nickel-titanium alloy.

[0055] See also Figure 2 In a further embodiment, the wavy support member 200 includes a first wavy support member 111, a second wavy support member 121 and a third wavy support member 131. The proximal support mechanism 110 includes a plurality of axially connected first wavy support members 111, the middle support mechanism 120 includes a plurality of axially connected second wavy support members 121, and the distal support mechanism 130 includes a plurality of axially connected third wavy support members 131. Each segment of the segmented stent 10 adopts an axially connected structure, so that the segmented marking stent 10 is more solid and stable as a whole, and avoids falling off and separation after being impacted by blood.

[0056] It is understandable that the first, second and third of the first wavy support member 111, the second wavy support member 121 and the third wavy support member 131 are used to distinguish the wavy support members 200 at different positions. It is understandable that the structures of the first wavy support member 111, the second wavy support member 121 and the third wavy support member 131 can be the same or different. It is further understandable that the first wavy support member 111, the second wavy support member 121 and the third wavy support member 131 can be uniformly distributed or non-uniformly distributed, that is, for example, the first wavy support member 111 can be composed of non-uniform waveforms or uniform waveforms, wherein the non-uniform waveforms include waveforms with different axial amplitudes but the same waveform lengths. The same is true for the second wavy support member 121 and the third wavy support member 131. Preferably, the second wavy support member 121 and the third wavy support member 131 are composed of uniform waveforms and form a closed loop structure.

[0057] See also Figure 3The second embodiment of the present invention provides a segmentation marking bracket 10a, in which the segmentation marking bracket 10a, the first wave-shaped support member 111 is composed of first support units 1110 connected end to end, the first support unit 1110 is composed of a first wave crest 1111, a first wave valley 1113 and a first wave rod 1112 connected between the first wave crest 1111 and the first wave valley 1113, and the first wave crest 1111 is arranged closer to the proximal end than the first wave valley 1113. It can be understood that the first wave rods 1112 adjacent to each other in the circumferential direction are connected near the proximal end to form the first wave crest 1111, and the first wave rods 1112 adjacent to each other in the circumferential direction are connected near the distal end to form the first wave valley 1113. The first wave rod 1112, the first wave crest 1111 and the first wave valley 1113 can be an integral structure or fixedly connected. It can also be understood that the shapes and sizes of the first support units 1110 at different positions in the first wave-shaped support member 111 may be the same or different.

[0058] The second wave-shaped support member 121 is composed of second support units 1210 connected end to end, and the second support unit 1210 is composed of a second wave crest 1211, a second wave trough 1213, and a second wave rod 1212 connected between the second wave crest 1211 and the second wave trough 1213, and the second wave crest 1211 is arranged closer to the proximal end than the second wave trough 1213. It can be understood that the circumferentially adjacent second wave rods 1212 are connected near the proximal end to form the second wave crest 1211, and the circumferentially adjacent second wave rods 1212 are connected near the distal end to form the second wave trough 1213. The second wave rod 1212, the second wave crest 1211, and the second wave trough 1213 can be an integral structure or fixedly connected.

[0059] The third wave-shaped support member 131 is composed of third support units 1310 connected end to end, and the third support unit 1310 is composed of a third wave crest 1311, a third wave trough 1313, and a third wave rod 1312 connected between the third wave crest 1311 and the third wave trough 1313, and the third wave crest 1311 is arranged closer to the proximal end than the third wave trough 1313. It can be understood that the circumferentially adjacent third wave rods 1312 are connected near the proximal end to form the third wave crest 1311, and the circumferentially adjacent third wave rods 1312 are connected near the distal end to form the third wave trough 1313. The third wave rod 1312, the third wave crest 1311, and the third wave trough 1313 can be an integral structure or fixedly connected.

[0060] It is understandable that the sizes of the first support unit 1110, the second support unit 1210 and the third support unit 1310 can be the same or different, and can be adaptively changed according to different bifurcated blood vessels or actual conditions so that the segmented stent 10 can achieve the best effect during the treatment process.

[0061] It can be understood that the first wave rod 1112, the second wave rod 1212 and the third wave rod 1312 can be a straight rod, a special-shaped rod with a curved structure or an arc structure, or a combination thereof. The special-shaped rod means that the first wave rod 1112, the second wave rod 1212 and the third wave rod 1312 are not straight rods, and the special-shaped rod with a curved structure means that a straight rod or an arc rod has a curved structure, and the curved structure means that the first wave rod 1112, the second wave rod 1212 and the third wave rod 1312 have a curved part, and the curved part can enhance the bending or stretching performance of the first wave rod 1112, the second wave rod 1212 and the third wave rod 1312. The curved structure can be set at any position of the first wave rod 1112, the second wave rod 1212 and the third wave rod 1312, and is preferably set in the middle of the first wave rod 1112, the second wave rod 1212 and the third wave rod 1312. Preferably, the special-shaped rod with a curved structure or an arc structure is an arc rod, a straight rod with an arc portion, a Z-shaped rod or an S-shaped rod. In the second embodiment, the first wave rod 1112, the second wave rod 1212 and the third wave rod 1312 are all straight rods. Fig.11 In the embodiment, the second wave rod 1212 adopts a straight rod and a special-shaped rod structure.

[0062] Please continue reading Figure 3 and Figure 4 In a further embodiment, the “development mark 140 is disposed on the wavy support member 200 connecting the proximal support mechanism 110 and / or the distal support mechanism 130 with the middle support mechanism 120” includes the development mark 140 being disposed on the first wavy support member 111 connecting the proximal support mechanism 110 with the middle support mechanism 120. The development mark 140 is used to mark the position of the stent 10a in the blood vessel at the development segment during surgery, so that the proximal support mechanism 110 can be accurately released at the vascular lesion, and the middle support mechanism 120 can be placed at other positions adjacent to the lesion.

[0063] In a further embodiment, the “development mark 140 is disposed on the first wave-shaped support member 111 connecting the proximal support mechanism 110 and the middle support mechanism 120” includes the development mark 140 being disposed at the first wave valley 1113 of the proximal support mechanism 110 closest to the middle support mechanism 120. Figure 3, four evenly spaced developing marks 140 are arranged on the first trough 1113 of the first wavy support member 111 closest to the middle support mechanism 120, and the developing marks 140 are fixed in the first trough 1113 position by stamping, hot pressing or sewing in a dotted form, or the developing material can be made into a developing wire, and then the developing marks 140 are wound around the first trough 1113 position in the form of a developing wire. By arranging the developing marks 140 at the intersection of the proximal support mechanism 110 and the middle support mechanism 120, the proximal support mechanism 110 with better support performance can be accurately released in the blood vessel subjected to greater radial pressure, and the middle support mechanism 120 can be released in the blood vessel with greater curvature, and the accuracy of the release of the segmented marking stent 10a in the blood vessel is improved by the display marks 140, so that the segmented marking stent 10a can give full play to the advantages of the segmented design. It can be understood that in this embodiment, the number of developing marks 140 can be adjusted according to needs.

[0064] See also Figure 5 The third embodiment of the present invention provides a segmented marking bracket 10b, wherein the developing mark 140 is arranged on the third wavy support member 131 connecting the distal support mechanism 130 and the middle support mechanism 120.

[0065] In a further embodiment, the “third wavy support member 131 disposed on the distal support mechanism 130 and the middle support mechanism 120” is disposed at the third wave crest 1311 of the distal support mechanism 130 closest to the middle support mechanism 120 (see Figure 5 ).

[0066] The development mark 140 may also be a combination of the second embodiment and the third embodiment.

[0067] See also Figure 6The fourth embodiment of the present invention provides a segmented marking bracket 10c, wherein four evenly spaced developing marks 140 are arranged on the first wave valley 1113 of the first wave-shaped supporting rod 111 of the proximal supporting mechanism 110 closest to the middle supporting mechanism 120. At the same time, four evenly spaced developing marks 140 are also arranged on the third wave peak 1313 of the third wave-shaped supporting rod 131 of the distal supporting mechanism 130 closest to the middle supporting mechanism 120 at the intersection of the distal supporting mechanism 130 and the middle supporting mechanism 120. By setting the developing mark 140 at the position where the proximal supporting mechanism 110 or the distal supporting mechanism 130 respectively intersects with the middle supporting mechanism 120, the proximal supporting mechanism 110 and the distal supporting mechanism 130 with better supporting performance can be accurately released in the blood vessel area that is subjected to greater radial compression, and the middle supporting mechanism 120 can be released in the blood vessel area with greater curvature. By displaying the mark 140, the accuracy of the release of the segmented marked stent 10c in the blood vessel is improved, so that the segmented stent can give full play to the advantages of the segmented design. It can be understood that in this embodiment, the number of developing marks 140 can be adjusted according to needs.

[0068] See also Figure 7 The fifth embodiment of the present invention provides a segmented marking bracket 10d, wherein “the developing mark 140 is arranged on the wavy support member 200 connecting the middle support mechanism 120 with the proximal support mechanism 110 and / or the distal support mechanism 130” includes the developing mark 140 being arranged on the second wavy support member 121 connecting the middle support mechanism 120 with the proximal support mechanism 110.

[0069] In a further embodiment, the “second wavy support member 121 disposed on the middle support mechanism 120 connecting the proximal support mechanism 110 ” includes a second wave peak 1211 disposed on the middle support mechanism 120 closest to the proximal support mechanism 110 .

[0070] See also Figure 8 The sixth embodiment of the present invention provides a segmented marking bracket 10e, wherein the developing mark 140 is arranged on the second wavy support member 121 connecting the middle support mechanism 120 and the distal support mechanism 130.

[0071] In a further embodiment, “being disposed on the second wavy support member 121 connecting the middle support mechanism 120 and the distal support mechanism 130 ” includes being disposed at the second trough 1211 position of the middle support mechanism 120 which is closest to the distal support mechanism 130 .

[0072] It is understandable that the four schemes in the second, third, fifth and sixth embodiments can be combined. It is also understandable that the number of the development marks 140 can be flexibly set as needed. The development marks 140 are set at the segmentation so that the three sections of the stent 10 with different radial support forces can be accurately released into the corresponding blood vessels, thereby improving the effect.

[0073] In a further embodiment, the display mark 140 is fixed on the corrugated support member 200 by stamping, hot pressing, sewing or winding. It is understandable that the display mark 140 can have various shapes, including dot, thread, square, circle, fan, etc. The corrugated support member 200 includes the first corrugated support member 111, the second corrugated support member 121 and the third corrugated support member 131.

[0074] In a further embodiment, the material forming / making the development mark includes one or more of gold, platinum, platinum-tungsten, palladium, platinum-iridium, rhodium, and tantalum.

[0075] In a further embodiment, the development mark 140 is that the wavy support member 200 connecting the proximal support mechanism 110 and / or the distal support mechanism 130 with the middle support mechanism 120 is made of an alloy containing a development material, or the development mark 140 is that the wavy support member 200 connecting the middle support mechanism 120 with the proximal support mechanism 110 and / or the distal support mechanism 130 is made of an alloy containing a development material. In other words, when the wavy support member 200 used to connect the two sections at the segmentation is manufactured, the alloy containing the development material is made at the position where development is required, and the development material and the material for manufacturing the wavy support member 200 are integrated. The development mark 140 manufactured in this way is not easy to fall off.

[0076] Please refer again Figure 3 , a plurality of support points 160 may be further provided at the ends of the proximal support mechanism 110 and / or the distal support mechanism 130. The support point 160 is a smooth raised structure provided on the first crest 1131 of the first wavy support member 113, and the raised structure may be a solid structure or a structure with a hole in the center. The number and interval of the raised structures are set according to actual needs and are not limited here. It is understandable that a developing mark 140 may be provided on the support point 160 to display the position reached by the end of the developing stent in the blood vessel during surgery. In this embodiment, the developing mark 140 is a developing mark 140 formed by filling a developing material in the center hole of the support point 160.

[0077] See also Fig. 9The seventh embodiment of the present invention provides a segmentation marking bracket 10f, in which the middle zone support mechanism 120 and the distal end support mechanism 130 are respectively annular structures. The proximal end support mechanism 110 includes a circumferential support portion 112 connected to the middle zone support mechanism 120 and a directional support portion 113 arranged at the proximal end of the circumferential support portion 112. The circumferential support portion 112 is an annular structure. The directional support portion 113 is open-loop in the circumferential direction to form a proximal end face 114, and the proximal end face 114 is a non-flush structure to form a local support in the circumferential direction.

[0078] In the above structure, the circumferential support portion 112 of the proximal support mechanism 110, the middle support mechanism 120 and the distal support mechanism 130 are all annular structures, so that the stent forms a tubular structure body, and the directional support portion 113 arranged at the nearest end of the stent is an open-loop structure.

[0079] In order to distinguish the first wavy support member 111 in the circumferential support portion 112 and the directional support portion 113, the first wavy support member in the circumferential support portion 112 is marked as the first wavy support member 111, and the first wavy support member in the directional support portion 113 is marked as 115, which is the fourth wavy support member 115. It can be understood that the shapes and sizes of the first wavy support member 111 and the fourth wavy support member 115 may be the same or different.

[0080] The proximal support mechanism 110 includes two parts, one is a circumferential support part 112 connected to the middle support mechanism 120, and the other is a directional support part 113 arranged at the most proximal end. The two parts are respectively composed of a first wave-shaped support member 111 and a fourth wave-shaped support member 115.

[0081] The annular shape of the present invention refers to the wavy support members 200 (including the first wavy support member 111, the second wavy support member 121, and the third wavy support member 131) being connected end to end to form a ring, and the open ring shape refers to the wavy support members 200 (including the fourth wavy support member 115) being separated end to end, and the wavy support members 200 are adjacent to each other or spaced a certain distance apart, and form an approximately annular or C-shaped structure in the axial projection.

[0082] The proximal end face 114 of the stent of the present invention is a non-flush structure suitable for bifurcated blood vessels, forming local support in the circumferential direction. The non-flush structure can set the inclination angle of the proximal end face 114 of the stent according to the intersection of the bifurcated blood vessels, so that the proximal end of the stent and the intersection of the blood vessels are completely fitted and covered, which can cover the lesion site without protruding into the main blood vessel, avoiding the problem in the prior art that the vascular stent cannot completely cover the lesion site after being implanted in the branch blood vessel or protrudes into the main blood vessel to affect the contralateral blood flow and cause complications.

[0083] The local support described in the directional support part 113 is due to the non-flush proximal end face 114, and the axial lengths of various positions in the radial direction are different. The proximal end face 114 refers to the axial side of the most proximal end of the stent. The stent is a tubular structure, and its end face is generally annular. Since the proximal end of the directional support part 113 is non-flush, an inclined or serrated proximal end is formed. Corresponding to the shape of the blood vessel near the intersection of the bifurcated blood vessels, the proximal end of the present invention adopts an inclined structure, that is, the non-flush structure of the directional support part 113 has multiple implementation methods. After the stent is expanded, it is preferred that the proximal end face of the directional support part 113 is in an inclined plane, arc surface or wavy surface. That is, the directional support part 113 is gradually extended from one side to the other side of the circumferential support part 112 in the radial direction, and the equidistant extension forms an inclined plane, and the non-equidistant extension forms an arc surface or a wavy surface. Preferably, the equidistant extension is used, and the proximal end face 114 is an inclined plane. The height difference between the outermost side and the innermost side is 1-30mm, preferably 5-20mm. The angle α between the inclined proximal end surface 114 and the central axis L of the stent satisfies: 90°>α>0°, preferably 60°>α>30°. The specific inclination angle is set according to the intersection angle and the diameter of the intersecting blood vessels, and is not limited here. The requirements of the present invention are met as long as it is within the above angle range.

[0084] In a further embodiment, the first wave crest 1111 in the first wave-shaped support member 111 is connected to the first wave trough 1113a in the first wave-shaped support member 111a which is axially adjacent and close to the proximal end, so that the proximal support mechanism 111 forms a grid structure.

[0085] In a further embodiment, the third wave crest 1311 in the third wave-shaped support member 131 is connected to the third wave trough 1313a in the axially adjacent third wave-shaped support member 131a, so that the distal support mechanism 130 forms a grid-like structure. It can be understood that the proximal support mechanism 110 and the distal support mechanism 130 are arranged in a grid shape, and the middle region support mechanism 120 is arranged in a ring shape rather than a grid shape. When the stent is used in a bifurcated blood vessel, the grid-like structures at both ends have good radial support force in the circumferential direction, which can avoid being deformed by the aorta near the bifurcated blood vessel, the arterial stent or the hard tissue near the bifurcated blood vessel. At the same time, the non-grid-shaped middle region support mechanism 120 has better flexibility than the proximal support mechanism 110 and the distal support mechanism 130, which can make the middle part adapt to the requirements of curved blood vessels.

[0086] In a further embodiment, the directional support portion 113 is a grid-like open-loop structure, and the number of grids decreases gradually from the distal end to the proximal end. Fig. 9The number of grids formed on the left side of the directional support portion 113 is less than the number of grids formed on the right side. Part of the grid-like structure is an incomplete grid-like structure. Due to the different circumferential lengths of the first wavy support members 111 on the proximal end face 114, the corresponding positions of some first wavy support members 111 are not connected to adjacent first wavy support members 111, and the wavy structure is retained, that is, the proximal end face 114 has a V-shaped and diamond-shaped structure. The first wavy support members 111 of the circumferential support portion 112 have the same circumferential length, which can achieve a one-to-one corresponding connection between the first wave crests and the first wave valleys of the adjacent first wave support members 111.

[0087] See also Fig.10 The eighth embodiment of the present invention provides a segmentation marking bracket 10g, in which the number of the first wave-shaped support members 111 in the axial direction of the proximal support mechanism 110 is the same, and the length of the first wave rod 1112 in the first wave-shaped support member 111 gradually increases from one side to the other side of the proximal support mechanism 110, so that the proximal end surface 114 forms an inclined surface. Fig.10 In the embodiment, the number of the first wave-shaped support members 111 in the axial direction is 8, forming 4 grids. The length of the first wave rods 1112 gradually increases from the left side to the right side.

[0088] See also Fig.11 The ninth embodiment of the present invention provides a segmentation marking stent 10h, in which the tubular stent 100 further includes a connecting assembly 150, and the proximal support mechanism 110 and the middle support mechanism 120, the middle support mechanism 120 and the distal support mechanism 130, or two adjacent second wavy support members 121 in the middle support mechanism 120 are connected by the connecting assembly 150. This makes the connection between each segment more firm and stable.

[0089] In a further embodiment, the connection assembly 150 includes at least one connection rod 151, and the “connection between the proximal support mechanism 110 and the middle support mechanism 120 via the connection assembly 150” includes the connection between the first wave crest 1111 and / or the first wave trough 1113 of the first wave-shaped support member 111 in the proximal support mechanism 110 and the second wave rod 1212 of the second wave-shaped support member 121 in the middle support mechanism 120 via the connection rod 151. Fig.11 In the embodiment, the first wave valley 1113 of the first wave-shaped support member 111 is connected to the second wave rod 1212 of the second wave-shaped support member 121 in the middle area support mechanism 120 via a connecting rod 151 .

[0090] It can also be understood that the first wave bar 1112 of the first wave-shaped support member 111 in the proximal support mechanism 110 and the second wave crest 1211 and / or the second wave trough 1213 of the second wave-shaped support member 121 in the middle region support mechanism 120 are connected via the connecting rod 151. Connecting one end of the connecting rod 151 to the second wave bar 1212 or the first wave bar 1112 further hinders the relative movement of the two ends of the connecting rod 151 and strengthens the fixation.

[0091] It can also be understood that the first wave crest 1111 and / or the first wave trough 1113 of the first wave-shaped support member 111 in the proximal support mechanism 110 and the second wave crest 1211 and / or the second wave trough 1213 of the second wave-shaped support member 121 in the middle region support mechanism 120 are connected via the connecting rod 151.

[0092] The “two adjacent second wavy support members 121 in the middle support mechanism 120 are connected by the connecting assembly 150” includes the second wave crest 1211 and / or second wave trough 1213 of the second wavy support member 121 in the middle support mechanism 120 being connected to the second wave bar 1212 of the adjacent second wavy support member 121 by the connecting rod 151. Fig.11 As shown, the second wave crest 1211 is connected to the second wave rod 1212 of the adjacent second wave-shaped support member 121 via a connecting rod 151.

[0093] It can be understood that the second wave crests 1211 and / or second wave valleys 1213 of the second wave-shaped support member 121 are connected to the second wave crests 1211 and / or second wave valleys 1213 of the adjacent second wave-shaped support member 121 via a connecting rod 151 .

[0094] The “connection between the middle support mechanism 120 and the distal support mechanism 130 via the connection assembly 150” includes the connection between the second wave rod 1212 of the second wave-shaped support member 121 in the middle support mechanism 120 and the third wave crest 1311 and / or third wave trough 1313 of the third wave-shaped support member 131 in the distal support mechanism 130 via the connection rod 151. Fig.11 As shown, the second wave rod 1212 is connected to the third wave peak 1311 in the third wave-shaped support member 131 via a connecting rod 151 .

[0095] It can be understood that the second wave crest 1211 and / or the second wave trough 1213 of the second wavy support member 121 in the middle support mechanism 120 is connected to the third wave bar 1312 of the third wavy support member 131 in the distal support mechanism 130 through the connecting rod 151. Alternatively, the second wave crest 1211 and / or the second wave trough 1213 of the second wavy support member 121 in the middle support mechanism 120 is connected to the third wave crest 1311 and / or the third wave trough 1313 of the third wavy support member 131 in the distal support mechanism 130 through the connecting rod 151.

[0096] In a further embodiment, the connection assembly 150 comprises at least two connection rods 151. In a ninth embodiment, the connection assembly 150 comprises two connection rods 151.

[0097] It is understandable that the two connecting rods 151 in the same connecting assembly 150 may be arranged in parallel (see Figure 8 ), or they may be arranged non-parallel, for example, two connecting rods 151 are arranged in an eight-shaped or inverted eight-shaped shape. In the present invention, it is preferably arranged in an eight-shaped or inverted eight-shaped shape, which can enhance the supporting force and improve the radial supporting force with the same number of connecting rods 151. Fig.11 In the embodiment, the connecting components 150a are arranged in an eight-shaped shape, and the connecting components 150b are arranged in an inverted eight-shaped shape. The connecting rods 151 of the middle zone support mechanism 120 are distributed in pairs, and form a closed-loop connection unit with the connected second wave-shaped support member 121, the first wave-shaped support member 113 or the third wave-shaped support member 131 and are evenly staggered, ensuring good flexibility, scalability and connection strength, and maintaining a good shape of the bracket and the wave shape when bending or stretching.

[0098] It is understandable that in Figure 2 One end of the two connecting rods 150 in the middle connecting assembly 150 is connected to the same wave crest (including the first wave crest, the second wave crest or the third wave crest) or wave trough (including the first wave trough, the second wave trough or the third wave trough), and the other ends of the two connecting rods 150 are respectively connected to two axially adjacent and circumferentially adjacent wave crests (including the first wave crest, the second wave crest or the third wave crest) or two wave troughs (including the first wave trough, the second wave trough or the third wave trough). And the figure-eight and inverted figure-eight connecting assemblies 150 are arranged alternately in the axial direction, for example, the connecting assembly 150 is in the figure-eight shape, and the connecting assembly 150 is in the inverted figure-eight shape. Figure 2 In the middle area support mechanism 120, two second wave-shaped support members 121 are arranged in the same row and overlapped and crossed to make the radial support force stronger.

[0099] In a further embodiment, the projections of the axially adjacent connecting assemblies 150 do not overlap or partially overlap in the axial direction; or all the connecting assemblies 150 are arranged in a spiral shape or staggered in the axial direction. The connecting rods 151 are evenly distributed in groups along the circumference, and two adjacent circles of connecting rods 151 are staggered in the axial direction, so that the connecting assemblies 150 can withstand greater local tension and pressure, and the stent can deform evenly when it is stretched or bent. When the projections of the axially adjacent connecting assemblies 150 partially overlap in the axial direction, the stent's retractability and connection strength can be better guaranteed, and the stent and the waveform can maintain a good shape when it is bent or stretched.

[0100] It is understandable that the connecting rod 151 is a straight rod, a shaped rod with a curved structure or an arc structure, or a combination thereof. Fig.11 shown.

[0101] In a further embodiment, the distance between two adjacent connecting rods 151 is at least the distance between two adjacent first wave valleys 1133, or at least the distance between two adjacent second wave valleys 1213, or at least the distance between two adjacent third wave peaks 1311. That is to say, the parts of two adjacent wavy support members 200 (numbered 111, 121 and 131) that are not connected to the connecting rods 151 are suspended and unconnected, so that there is a large relative movement or bending space between the two adjacent wavy support members 200 (numbered 111, 121 and 131) in the radial and axial directions, thereby increasing the flexibility of the stent. Figure 3-Figure 8 , is the distance between two adjacent first wave valleys 1133 between two connecting rods 151 , or the distance between two adjacent second wave valleys 1213 , or the distance between two adjacent third wave peaks 1311 .

[0102] See also Fig.12 The tenth embodiment of the present invention provides a segmented marking stent 10i. In the segmented marking stent 10i, in order to strengthen the fit between the tubular stent 100 and the inner wall of the blood vessel, the proximal end of the directional support portion 113 gradually extends and expands outward from the tubular stent 100 in the proximal direction from the distal end. The proximal end of the directional support portion 113 extends and expands outward from the tubular stent 100 to form an expansion portion 116. The angle β between the outer contour line of the expansion portion 116 and the center axis L of the stent satisfies: 30°≥β>0°. That is, the directional support portion 112 extends from the circumferential support portion 111 in the axial direction toward the proximal end, and also gradually extends outward in the radial direction to form an outward-turned trumpet-mouth structure. The degree of outward turn should not be too large. Preferably, at least the angle β between the longest axial section of the directional support portion 112 and the center axis L of the stent satisfies: 30°≥β>0°, that is, the directional support portion 112 is slightly outward-turned. Fig.14As shown, in this embodiment, the proximal closed loop area gradually expands radially outward at an angle β of 20° from the distal end to the proximal end. The tubular structure expands outward at a certain angle at the proximal end, which is more in line with the anatomy of the bifurcated blood vessels, so that the proximal end of the stent achieves a good wall adhesion effect.

[0103] See also Fig.13 The eleventh embodiment of the present invention provides a segmentation marking stent 10j. In the segmentation marking stent 10j, the outer diameter of the tubular stent 100 gradually expands from the distal end to the proximal end to form a tapered structure. It can be understood that the tubular stent 100 in the segmented stent 10 of the present invention can be a straight tubular structure, or a truncated cone-shaped tubular structure, or the proximal support mechanism 110 can be set to gradually reduce the radial diameter from the proximal end to the distal end, while the middle support mechanism 120 and the distal support mechanism 130 are of equal diameter. It can be understood that the diameter of each segment of the tubular stent 100 can be adjusted according to actual conditions to meet the requirements of different blood vessels.

[0104] The above-mentioned embodiments only express several implementation methods of the present invention, and the description thereof is relatively specific and detailed, but it cannot be understood as limiting the scope of the patent of the present invention. It should be pointed out that, for ordinary technicians in this field, several variations and improvements can be made without departing from the concept of the present invention, which all belong to the protection scope of the present invention. Therefore, the protection scope of the patent of the present invention shall be subject to the attached claims.

Claims

1. A segment marking bracket, characterized in that: The segmented marking bracket includes a tubular bracket formed by a plurality of axially connected wavy support members and a development mark, and the tubular bracket includes a proximal support mechanism, a middle region support mechanism and a distal support mechanism connected in sequence; the development mark is arranged on the wavy support member connecting the proximal support mechanism and / or the distal support mechanism with the middle region support mechanism, or the development mark is arranged on the wavy support member connecting the middle region support mechanism with the proximal support mechanism and / or the distal support mechanism; the proximal support mechanism includes a circumferential support portion connected to the middle region support mechanism and a directional support portion arranged at the proximal end of the circumferential support portion; The circumferential support portion is an annular structure; the directional support portion is open in the circumferential direction to form a proximal end face, and the proximal end face is a non-flush structure to form a local support in the circumferential direction; the outer diameter of the tubular support gradually expands from the distal end to the proximal end; the wavy support member includes a first wavy support member, a second wavy support member and a third wavy support member; the proximal support mechanism includes a plurality of axially connected first wavy support members, the middle zone support mechanism includes a plurality of axially connected second wavy support members, and the distal support mechanism includes a plurality of axially connected third wavy support members; the first wavy support member is composed of a first support unit connected end to end, and the first support unit is composed of a first wave crest, a first wave trough and a connecting The first wave rod is between the first wave crest and the first wave trough, and the first wave crest is arranged closer to the proximal end than the first wave trough; the second wave-shaped support member is composed of second support units connected end to end, the second support unit is composed of a second wave crest, a second wave trough and a second wave rod connected between the second wave crest and the second wave trough, and the second wave crest is arranged closer to the proximal end than the second wave trough; the third wave-shaped support member is composed of third support units connected end to end, the third support unit is composed of a third wave crest, a third wave trough and a third wave rod connected between the third wave crest and the third wave trough, and the third wave crest is arranged closer to the proximal end than the third wave trough.

2. The segmented marking bracket according to claim 1, characterized in that: The development mark is arranged on the wavy support member connecting the proximal support mechanism and / or the distal support mechanism with the middle support mechanism, including the development mark being arranged on the first wavy support member connecting the proximal support mechanism with the middle support mechanism; or being arranged on the third wavy support member connecting the distal support mechanism with the middle support mechanism; The developing mark is arranged on the wavy support member connecting the middle area supporting mechanism with the proximal supporting mechanism and / or the distal supporting mechanism, including the developing mark being arranged on the second wavy support member connecting the middle area supporting mechanism with the proximal supporting mechanism; or being arranged on the second wavy support member connecting the middle area supporting mechanism with the distal supporting mechanism.

3. The segmented marking bracket according to claim 2, characterized in that: The developing mark is arranged on the first wave-shaped support member connecting the proximal supporting mechanism and the middle supporting mechanism, including the developing mark being arranged at the first wave valley position of the proximal supporting mechanism closest to the middle supporting mechanism; The third wave-shaped support member disposed on the connection between the distal support mechanism and the middle support mechanism includes a third wave crest position disposed on the distal support mechanism closest to the middle support mechanism; The developing mark is arranged on the second wave-shaped support member connecting the middle support mechanism and the proximal support mechanism, including the developing mark being arranged at the second wave crest position of the middle support mechanism closest to the proximal support mechanism; The second wave-shaped support member disposed on the connection between the middle support mechanism and the distal support mechanism includes a second wave valley position disposed on the middle support mechanism closest to the distal support mechanism.

4. The segmented marking bracket according to claim 1, characterized in that: The developing mark is fixed on the corrugated support member by punching, hot pressing, sewing or winding.

5. The segmented marking bracket according to claim 1, characterized in that: The material used to form / make the development mark includes one or more of gold, platinum, platinum-tungsten, palladium, platinum-iridium, rhodium, and tantalum.

6. The segmented marking bracket according to claim 1, characterized in that: The middle area support mechanism and the distal end support mechanism are respectively annular structures.

7. The segmented marking bracket according to claim 6, characterized in that: The proximal end surface is an inclined plane, a curved surface or a wavy surface.

8. The segmented marking bracket according to claim 7, characterized in that: The proximal end surface is an inclined plane, and the angle α between the proximal end surface and the central axis of the segmented marking bracket satisfies: 90°>α>0°.

9. The segmented marking bracket according to claim 6, characterized in that: The directional support portion is a grid-like open-loop structure, and the number of grids decreases gradually from the distal end to the proximal end.

10. The segmented marking bracket according to claim 6, characterized in that: The first wave crest in the first wave-shaped support member is connected to the first wave trough in the first wave-shaped support member which is axially adjacent and close to the proximal end, so that the proximal support mechanism forms a grid-like structure.

11. The segmented marking bracket according to claim 6, characterized in that: The tubular stent also includes a connecting component, through which the proximal support mechanism and the middle support mechanism, the middle support mechanism and the distal support mechanism, or two adjacent second wavy support members in the middle support mechanism are connected.

12. The segmented marking bracket according to claim 11, characterized in that: The connecting assembly includes at least one connecting rod, and the connection between the proximal support mechanism and the middle region support mechanism through the connecting assembly includes the connection between the first wave crest and / or the first wave trough of the first wave-shaped support member in the proximal support mechanism and the second wave rod of the second wave-shaped support member in the middle region support mechanism through the connecting rod, or the connection between the first wave rod of the first wave-shaped support member in the proximal support mechanism and the second wave crest and / or the second wave trough of the second wave-shaped support member in the middle region support mechanism through the connecting rod; The connection assembly connects two adjacent second wavy support members in the middle zone support mechanism, including the connection between the second wave crest and / or second wave trough of the second wavy support member in the middle zone support mechanism and the second wave bar of the adjacent second wavy support member through the connecting rod; The middle area support mechanism and the distal support mechanism are connected through the connecting assembly, including the connection between the second wave rod of the second wavy support member in the middle area support mechanism and the third wave peak and / or third wave trough of the third wavy support member in the distal support mechanism through the connecting rod, or the connection between the second wave peak and / or second wave trough of the second wavy support member in the middle area support mechanism and the third wave rod of the third wavy support member in the distal support mechanism through the connecting rod.

13. The segmented marking bracket according to claim 11, characterized in that: The same connection assembly includes at least two connection rods, and the adjacent connection rods are arranged in an eight-shaped or inverted eight-shaped shape.

14. The segmented marking bracket according to claim 11, characterized in that: The projections of the axially adjacent connection components in the axial direction do not overlap or partially overlap.

15. The segmented marking bracket according to claim 6, characterized in that: The proximal end of the directional support portion gradually extends and expands outside the tubular support from the distal end to the proximal end.

16. The segmented marking bracket according to claim 15, characterized in that: The proximal end of the directional support portion extends outward from the tubular stent to form an expansion portion, and the included angle β between the outer contour line of the expansion portion and the central axis of the stent satisfies: 30°≥β>0°.

17. The segmented marking bracket according to claim 6, characterized in that: The third wave crest in the third wave-shaped support member is connected to the third wave trough in the third wave-shaped support member which is axially adjacent and close to the proximal end, so that the distal support mechanism forms a grid-like structure.

18. The segmented marking bracket according to claim 1, characterized in that: The developing mark is that the wavy support member connecting the proximal supporting mechanism and / or the distal supporting mechanism with the middle supporting mechanism is made of an alloy containing developing material, or the developing mark is that the wavy support member connecting the middle supporting mechanism with the proximal supporting mechanism and / or the distal supporting mechanism is made of an alloy containing developing material.

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