A liquid delay structure
By designing a buffer chamber and an inverted U-shaped second flow channel in the liquid delay structure of the reagent disk, the problem of delayed addition of liquid is solved, and effective control of the time when the liquid enters the liquid storage chamber is achieved.
Patent Information
- Application Number
- CN201911300105.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2019-12-17
- Publication Date
- 2025-04-22
- Estimated Expiration
- 2039-12-17
AI Technical Summary
In modern medical testing, it is difficult for the prior art to realize the delayed addition function of liquid, especially in the design of reagent trays, which cannot effectively control the time when the liquid enters the liquid storage chamber.
A liquid delay structure is designed, including a first liquid storage chamber, a buffer chamber and a second flow channel in an inverted U-shaped shape. The liquid flows into the first flow channel through external force and preferentially enters the buffer chamber. When the liquid level of the buffer chamber is higher than the top of the second flow channel, the liquid enters the second liquid storage chamber to realize the delay function.
By adjusting the fluid resistance of the first flow channel and the U-shaped top position of the second flow channel, the time when the liquid enters the second liquid storage chamber can be effectively controlled, and the delayed addition function of the liquid can be realized.
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Figure CN110865181B_ABST
Abstract
Description
Technical Field
[0001] The invention relates to a liquid time-delay structure. Background Art
[0002] In modern medical testing, the use of reagent discs to test body fluids is an emerging testing method. It uses the method of dripping body fluids into a reagent disc, using the rotation of the reagent disc to generate centrifugal force, or using a pressure device to pressurize the liquid outward, and then using different flow channels and liquid storage chamber designs to achieve a series of operations such as quantification, separation, and equal division of body fluids. In combination with different testing reagents, multiple testing functions can be completed on the same reagent disc, which is simple and convenient to use and faster to test. In these operations, sometimes the operation of adding liquids at a fixed time is used, and the third reagent is added after two reagents react for a period of time. Summary of the invention
[0003] The technical problem to be solved by the present invention is to provide a liquid delay structure, which can delay the addition of liquid into a specified liquid storage chamber.
[0004] The technical solution adopted by the present invention is: a liquid delay structure, which includes a first liquid storage chamber, a first flow channel connected to the first liquid storage chamber, a buffer chamber and a second flow channel respectively connected to the first flow channel, and a second liquid storage chamber connected to the other end of the second flow channel, the second flow channel is an inverted U-shape, and its top end is higher than the lowest end of the buffer chamber, and the liquid in the first liquid storage chamber flows to the first flow channel under the action of external force.
[0005] Furthermore, air holes are arranged on the first liquid storage chamber, the buffer chamber and the second liquid storage chamber.
[0006] Furthermore, the buffer chamber and the second flow channel are located on the left and right sides of the first flow channel.
[0007] Furthermore, the first liquid storage chamber, the buffer chamber, and the second liquid storage chamber are arranged on a rotating reagent disk, and the first liquid storage chamber, the buffer chamber, and the second liquid storage chamber are arranged radially outward in sequence, and the liquid flows out of the first liquid storage chamber due to the centrifugal force of the rotating reagent disk.
[0008] Furthermore, the U-shaped top end of the second flow channel is radially inward relative to the bottom end of the buffer chamber.
[0009] Furthermore, a pressurizing device is connected to the first liquid storage chamber to press the liquid out by increasing the pressure in the first liquid storage chamber.
[0010] Furthermore, the U-shaped top end of the second flow channel is located between the lowest end and the highest end of the buffer chamber.
[0011] The positive effect of the present invention is as follows: the present invention connects the buffer chamber and the inverted U-shaped second flow channel through the first liquid storage chamber. When the liquid in the first liquid storage chamber flows into the first flow channel under the action of external force, it first flows into the buffer chamber. When the buffer chamber is full or the liquid level therein is higher than the top of the second flow channel, the liquid will enter the second liquid storage chamber. By changing the fluid resistance of the first flow channel and the position of the U-shaped top of the second flow channel, the time for the liquid to flow into the second liquid storage chamber can be adjusted. BRIEF DESCRIPTION OF THE DRAWINGS
[0012] Figure 1 It is a schematic diagram of the structure of the present invention.
[0013] In the attached drawings, 1-first liquid storage chamber, 2-buffer chamber, 3-first flow channel, 4-second flow channel, 5-second liquid storage chamber, 6-reagent disk, 7-air hole. DETAILED DESCRIPTION
[0014] Example 1
[0015] As attached Figure 1 As shown, the present invention includes a first liquid storage chamber 1, a first flow channel 3, a buffer chamber 2, a second flow channel 4 and a second liquid storage chamber 5. The first flow channel 3 is connected to the bottom end of the first liquid storage chamber 1, one end of the second flow channel 4 and the buffer chamber 2 are respectively connected to the bottom end of the first flow channel 3 and are located on both sides of the first flow channel 3, the second flow channel 4 is an inverted U-shape, the second liquid storage chamber 5 is connected to the other end of the second flow channel 4, and the second liquid storage chamber 5 is located below the first liquid storage chamber 1.
[0016] Air holes 7 are provided on the first liquid storage chamber 1 , the buffer chamber 2 and the second liquid storage chamber 5 .
[0017] In this embodiment, the above components are all arranged on the rotating reagent disk 6, and under the action of centrifugal force, the liquid in the first liquid storage chamber 1 flows into the first flow channel 3. The first liquid storage chamber 1, the buffer chamber 2, and the second liquid storage chamber 5 are sequentially arranged radially outward on the reagent disk 6. The rotation radius of the U-shaped top end of the second flow channel 4 is located between the top end and the bottom end rotation radius of the buffer chamber 2.
[0018] When liquid is added to the first liquid storage chamber 6 and the reagent disk 6 rotates, the liquid flows from the first liquid storage chamber 6 into the buffer chamber 2 through the first flow channel 3 under the action of centrifugal force. Since the U-shaped top of the second flow channel 4 is located between the top and bottom of the buffer chamber 2, when the liquid level in the buffer chamber 2 is not higher than the U-shaped top of the second flow channel, the liquid will not enter the second flow channel 4 and will preferentially enter the buffer chamber 2. When the liquid level in the buffer chamber 2 is higher than the U-shaped top of the second flow channel, the liquid begins to flow into the second liquid storage chamber 5.
[0019] The delay time of the liquid flowing into the second liquid storage chamber 5 is determined by the fluid resistance of the first flow channel 3 and the position of the U-shaped top (i.e., the most radially inward) part of the second flow channel. The greater the fluid resistance, the more radially inward the U-shaped top of the second flow channel 4 is, and the longer the delay time.
[0020] Example 2
[0021] On the basis of Example 1, the structure of the reagent disk 6 is removed, and a pressurizing device is connected to the air hole 7 of the first liquid storage chamber to increase the pressure in the first liquid storage chamber 1 so that the liquid flows out. This can also achieve the effect of liquid delay.
[0022] The present invention adds a buffer chamber and an inverted U-shaped second flow channel 4 between the two liquid storage chambers. When the liquid flows out of the first liquid storage chamber 1 under the action of external force, it will preferentially enter the buffer chamber 2. When the liquid level in the buffer chamber 2 is higher than the liquid level in the second flow channel 4, the liquid will bypass the U-shaped top of the second flow channel 4 and enter the second liquid storage chamber 5, thereby realizing the liquid delay function.
[0023] The delay time can be adjusted by adjusting the fluid resistance of the first flow channel 3 and the distance between the U-shaped top end of the second flow channel 4 and the first liquid storage chamber.
Claims
1. A liquid delay structure, characterized in that It comprises a first liquid storage chamber (1), a first flow channel (3) connected to the first liquid storage chamber (1), a buffer chamber (2) and a second flow channel (4) respectively connected to the first flow channel (3), and a second liquid storage chamber (5) connected to the other end of the second flow channel (4); the second flow channel (4) is in an inverted U shape, the top of which is higher than the lowest end of the buffer chamber (2); the second liquid storage chamber (5) is lower than the first liquid storage chamber (1); the liquid in the first liquid storage chamber (1) flows toward the first flow channel (3) under the action of an external force; air holes (7) are provided on the first liquid storage chamber (1), the buffer chamber (2) and the second liquid storage chamber (5); the buffer chamber (2) and the second flow channel (4) are located on the left and right sides of the first flow channel (3); The first liquid storage chamber (1), the buffer chamber (2), and the second liquid storage chamber (5) are arranged on a rotating reagent disk (6); the first liquid storage chamber (1), the buffer chamber (2), and the second liquid storage chamber (5) are arranged radially outward in sequence, and the liquid flows out of the first liquid storage chamber (1) due to the centrifugal force of the rotating reagent disk (6); Liquid is added to the first liquid storage chamber (1), and when the reagent disk (6) rotates, the liquid flows from the first liquid storage chamber (1) into the buffer chamber (2) through the first flow channel (3) under the action of centrifugal force. When the liquid level in the buffer chamber (2) is higher than the U-shaped top of the second flow channel (4), the liquid begins to flow into the second liquid storage chamber (5); The U-shaped top end of the second flow channel (4) is located between the lowest end and the highest end of the buffer chamber (2); The first flow channel (3) is connected to the bottom of the buffer chamber (2), and the other end of the second flow channel (4) is connected to the bottom of the second liquid storage chamber (5); air holes (7) are provided at the tops of the buffer chamber (2) and the second liquid storage chamber (5).
2. A liquid delay structure according to claim 1, characterized in that The U-shaped top end of the second flow channel (4) is radially inward relative to the bottom end of the buffer chamber (2).
3. A liquid delay structure according to claim 1, characterized in that The first liquid storage chamber (1) is connected to a pressurizing device, which presses out the liquid by increasing the pressure in the first liquid storage chamber (1).
Citation Information
Patent Citations
Centrifugal microfluidic platform
US20140134631A1