Rotary tablet press and tablet press cleaning method

Abstract

The present invention relates to the technical field of pharmaceutical equipment, and in particular to a rotary tablet press and a cleaning method for the tablet press. A detachable sealed cabin is installed in the tablet press chamber of the rotary tablet press, and the sealed cabin includes a shell, a punching disc unit, a suction mechanism and a spray mechanism. The punching disc unit, the suction mechanism and the spray mechanism are all installed in the shell. A workstation area for pressing materials is provided on the punching disc unit, the suction mechanism is connected to the workstation area, and the spray mechanism is installed around the workstation area. The tablet press uses a sealed cabin to completely isolate the punching disc unit from the outside, so that all powders generated during the tablet production process are isolated in the sealed cabin; the spray mechanism in the sealed cabin is used to pre-clean the punching disc unit after production and in the cleaning and maintenance links, and after pre-cleaning, the sealed cabin is removed from the tablet press chamber and cleaned separately in conjunction with the detachability of the sealed cabin, thereby avoiding direct contact between the operator and the drug powder in the cleaning and maintenance links.

Description

Technical Field

[0001] The invention relates to the technical field of pharmaceutical equipment, and in particular to a rotary tablet press and a cleaning method for the tablet press. Background Art

[0002] Tablet press is a machine that presses granules or powdered materials into tablets through a die. Due to the diversity of tablet products, the raw materials of tablets are relatively complex, some of which contain hormone components. With the improvement of comprehensive strength, many pharmaceutical companies have begun to develop and produce anti-cancer drugs. The contact between these products and the operators of tablet presses will cause cross contamination. More importantly, the dust leaked during the production and cleaning process will cause damage to the health of the operators.

[0003] With the increasingly comprehensive provisions on labor safety protection and the increase in labor costs, how to minimize the contact between operators and materials and products has become a key research topic for tablet press manufacturers. The direct contact between operators and drug powder mainly comes from the flying dust during normal production and direct contact during cleaning and maintenance. Therefore, how to avoid direct contact between operators and drug powder in normal production and cleaning and maintenance is an urgent problem to be solved in tablet press manufacturing. Summary of the invention

[0004] 1. Technical issues to be resolved

[0005] The embodiments of the present invention provide a rotary tablet press and a cleaning method for the tablet press, so as to solve the defect in the prior art that it is difficult to avoid direct contact between the operator and the medicine powder in the normal production link and the cleaning and maintenance link of the tablet press.

[0006] (II) Technical solution

[0007] In order to solve the above technical problems, the present invention provides a rotary tablet press, including a tablet pressing chamber, in which a detachable sealed cabin is installed, the sealed cabin includes a shell, a punching disc unit, a suction mechanism and a spray mechanism, the punching disc unit, the suction mechanism and the spray mechanism are all installed in the shell, the punching disc unit is provided with a work station area for pressing materials, the suction mechanism is connected to the work station area, and the spray mechanism is installed around the work station area.

[0008] In some embodiments, the shell includes an upper cover, a bottom plate and a cabin plate, the upper cover and the bottom plate are vertically arranged opposite to each other, and the cabin plates are respectively sealed and connected between the upper cover and the bottom plate.

[0009] In some embodiments, the upper cover and the bottom plate are coaxially arranged relative to each other, the punch disc unit is installed between the upper cover and the bottom plate, and the axis of the punch disc unit coincides with the axis of the bottom plate.

[0010] In some embodiments, the suction mechanism is fixed to the side of the punching disc unit, a suction port is provided at one end of the suction mechanism, the suction port faces the work station area, and the other end of the suction mechanism passes through the bottom plate and is connected to the negative pressure drive system.

[0011] In some embodiments, a plurality of the spray mechanisms are installed on the lower surface of the upper cover.

[0012] In some embodiments, a drain port is installed on the bottom plate.

[0013] In some embodiments, the sealed cabin also includes a feeding mechanism, which includes a feeder and a hopper. The feeder is installed in the shell and fixed to the side of the punching disc unit. The upper cover is provided with a feeding port. One end of the feeder is connected to the feeding port, and the other end is connected to the work station area. The feeding port is connected to the hopper through a flexible connecting section.

[0014] In some embodiments, a transparent window is provided on the cabin panel.

[0015] In some embodiments, a cantilever mechanism, a lifting shaft and a mounting seat are also installed in the tablet pressing chamber. The mounting seat is fixed on the top of the sealed cabin, one end of the lifting shaft is connected to the mounting seat along the axis of the mounting seat, the other end of the lifting shaft is connected to one end of the cantilever mechanism, and the other end of the cantilever mechanism is connected to a lifting drive mechanism and a rotating drive mechanism.

[0016] The present invention provides a cleaning method based on the rotary tablet press as described above, comprising:

[0017] Pre-cleaning process: using the spray mechanism to spray the punching disc unit located inside the shell; and

[0018] Disassembly and cleaning process: the sealed cabin is disassembled as a whole from the tablet pressing chamber and cleaned.

[0019] (III) Beneficial effects

[0020] The above technical scheme of the present invention has the following beneficial effects: the rotary tablet press of the present invention comprises a tablet pressing chamber, a detachable sealed cabin is installed in the tablet pressing chamber, the sealed cabin comprises a shell, a punching disc unit, a suction mechanism and a spray mechanism, the punching disc unit, the suction mechanism and the spray mechanism are all installed in the shell, a workstation area for pressing materials is provided on the punching disc unit, the suction mechanism is connected to the workstation area, and the spray mechanism is installed around the workstation area. The tablet press seals the punching disc unit as a whole in the shell of the sealed cabin, thereby ensuring that the punching disc unit is completely isolated from the outside of the tablet press when the material is pressed, so that the powder generated in the tablet production process is isolated in the sealed cabin; the tablet press also uses the spray mechanism in the sealed cabin to pre-clean the punching disc unit after production and in the cleaning and maintenance links, and after pre-cleaning, the sealed cabin is removed from the tablet pressing chamber and cleaned separately in conjunction with the detachable performance of the sealed cabin, thereby avoiding direct contact between the operator and the drug powder in the cleaning and maintenance links. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0022] Figure 1 It is a structural schematic diagram of a rotary tablet press according to an embodiment of the present invention;

[0023] Figure 2 Schematic diagram of the structure of the tablet pressing chamber of an embodiment of the present invention.

[0024] Reference numerals:

[0025] 1: tablet pressing chamber; 2: transmission system; 3: punching plate unit; 4: feeder; 5: feeding port; 6: suction mechanism; 7: tablet discharging mechanism; 8: sealing cabin; 9: spray mechanism; 10: drain outlet; 11: guide plate; 12: punching die; 13: pressing wheel mechanism; 14: hopper; 15: flexible connecting joint; 16: upper cover; 17: bottom plate; 18: cabin plate; 19: transparent window; 20: mounting seat; 21: lifting shaft; 22: cantilever mechanism. DETAILED DESCRIPTION

[0026] The following embodiments of the present invention are described in further detail in conjunction with the accompanying drawings and examples. The following examples are used to illustrate the present invention, but are not intended to limit the scope of the present invention.

[0027] In the description of the present invention, unless otherwise specified, "multiple" means two or more than two; unless otherwise specified, "notch-shaped" means a shape other than a flat cross-section. The orientation or positional relationship indicated by the terms "upper", "lower", "left", "right", "inner", "outer", "front end", "rear end", "head", "tail", etc. is based on the orientation or positional relationship shown in the accompanying drawings, and is only for the convenience of describing the present invention and simplifying the description, and does not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operate in a specific orientation, and therefore cannot be understood as a limitation on the present invention. In addition, the terms "first", "second", "third", etc. are used for descriptive purposes only and cannot be understood as indicating or implying relative importance.

[0028] like Figure 1 As shown, the rotary tablet press (hereinafter referred to as tablet press) provided in this embodiment includes a tablet press chamber 1, a transmission system 2 is installed at the lower part of the tablet press chamber 1, and a punching disc unit 3 is installed in the tablet press chamber 1. The punching disc unit 3 is provided with a workstation area for pressing materials. The drug powder as the material enters the workstation area and is pressed into tablets. In this process, since all key links of tablet preparation are completed in the punching disc unit 3, the powder is concentrated in the punching disc unit 3.

[0029] Since the generation of dust is unavoidable, in order to prevent dust from leaking from the tablet press, a detachable sealed cabin 8 is installed in the tablet press chamber 1. The sealed cabin 8 is flexible and detachable and can be directly taken out of the tablet press chamber 1 during the cleaning and maintenance stage, which means that the punching disc unit 3 in the sealed cabin 8 and the excess dust generated by it are directly, completely and airtightly taken away from the tablet press chamber 1 by the sealed cabin 8, so that the punching disc unit 3 can be cleaned separately offline in the cleaning mechanism outside the tablet press.

[0030] like Figure 2 As shown, the sealed cabin 8 includes a shell and a punching disc unit 3, a suction mechanism 6 and a spray mechanism 9 installed in the shell. The suction mechanism 6 is connected to the work area on the punching disc unit 3. The suction mechanism 6 can not only suck away the excess dust generated in the work area, but also suck the inside of the sealed cabin 8 into a negative pressure state, thereby providing a double guarantee for the dust in the punching disc unit 3 not to leak out. The spray mechanism 9 is installed around the work area. After the punching disc unit 3 completes production, the cleaning liquid is sprayed into the shell through the spray mechanism 9, and the punching disc unit 3 in contact with the material is automatically moistened, thereby pre-cleaning each device in the shell.

[0031] The tablet press seals the punching disc unit 3 as a whole in the shell of the sealed cabin 8, thereby ensuring that the punching disc unit 3 is completely isolated from the outside of the tablet press when pressing materials, so that the powder generated in the tablet production process is isolated in the sealed cabin 8; the tablet press also uses the spray mechanism 9 in the sealed cabin 8 to pre-clean the punching disc unit 3 after production and in the cleaning and maintenance links, and after pre-cleaning, the sealed cabin 8 is removed from the tablet pressing chamber 1 and cleaned separately in conjunction with the detachable performance of the sealed cabin 8, thereby avoiding direct contact between the operator and the powder during the cleaning and maintenance links.

[0032] In a preferred embodiment, the housing includes an upper cover 16, a bottom plate 17 and a hatch 18, the upper cover 16 and the bottom plate 17 are arranged vertically opposite to each other, and the hatch 18 is respectively sealed and connected between the upper cover 16 and the bottom plate 17. Specifically, the upper cover 16 and the bottom plate 17 are placed flat on the upper and lower sides of the punching disc unit 3, and the upper cover 16 and the bottom plate 17 are coaxially arranged opposite to each other, the punching disc unit 3 is installed between the upper cover 16 and the bottom plate 17, and the axis of the punching disc unit 3 coincides with the axis of the bottom plate 17; the hatch 18 is vertically connected between the edges of the upper cover 16 and the bottom plate 17, so that the upper cover 16, the hatch 18 and the bottom plate 17 are used to enclose a closed space, and the punching disc unit 3 is installed in the closed space.

[0033] In order to facilitate observation of the internal conditions of the shell, a transparent window 19 is preferably installed on the cabin plate 18. The transparent window 19 can be made of corrosion-resistant glass or transparent resin material.

[0034] In order to enhance the airtightness of the shell, the upper cover 16 and the bottom plate 17 are respectively sealed with the cabin plate 18 by high-strength silicone sealants, thereby ensuring that the dust generated during the tablet production process is completely enclosed in the sealed cabin 8.

[0035] It should be understood that the punching disc unit 3 described in this embodiment includes a punching disc assembly, a punching die 12, a punching rod and a guide rail. A rotating shaft is provided on the bottom plate 17 along the axis of the bottom plate 17. The punching disc assembly is mounted on the rotating shaft. The rotating shaft is connected to the transmission system 2 to drive the punching disc assembly to rotate as a whole. The punching disc assembly includes an upper punching disc, a middle punching disc and a lower punching disc which are sequentially mounted outside the rotating shaft from top to bottom. The upper punching disc is connected to a guide plate 11. A curved track is provided on the circumferential side wall of the guide plate 11. A plurality of upper punching rods that can move vertically are installed on the circumference of the upper punching disc. A pressing wheel mechanism 13 that moves along the curved track on the track plate is provided at the top of all the upper punching rods. When the upper punching disc drives all the upper punching rods to rotate, each upper punching rod moves along the curved track under the action of the pressing wheel mechanism 13, so that each upper punching rod moves vertically up and down one by one during rotation. A punching die 12 is provided between the bottom of each upper punching rod and the middle punching disc, and the above-mentioned workstation area is provided between the punching die 12 and the middle punching disc. During the tablet production process, the upper punch rod is pressed vertically downward by the pressing wheel mechanism 13, thereby generating a counter-pressing effect with the middle punch plate, and the granules or powder materials in the die 12 are pressed into tablets by the counter-pressing effect.

[0036] It can be understood that in the above-mentioned punching disc unit 3, the punching disc assembly, the die 12 and the punch rod are all installed in the shell, the pressure wheel mechanism 13 is installed above the shell, the guide rail passes through the upper cover 16 of the shell and is connected to the pressure wheel mechanism 13, and the sealing connection between the upper punching disc and the upper cover 16 is utilized to prevent excess dust in the work station area from leaking out from the guide rail.

[0037] It is understandable that a discharging mechanism 7 is provided on the side of the sealed cabin 8, one end of which penetrates into the cabin plate 18 and is connected to the workstation area, and the other end leads to the outside of the tablet press. The tablets completed in the workstation area are transported to the outside of the tablet press by the discharging mechanism 7.

[0038] In a preferred embodiment, the sealed cabin 8 also includes a feeding mechanism, which includes a feeder 4 and a hopper 14. The feeder 4 is installed in the shell and fixed to the side of the punching disc unit 3. A feeding port 5 is provided on the upper cover 16. One end of the feeder 4 is connected to the feeding port 5, and the other end is connected to the work station area. The feeding port 5 is connected to the hopper 14 through a flexible connecting section 15.

[0039] It is understandable that the flexible connection section 15 is connected between the hopper 14 and the feeding port 5, and the inside of the flexible connection section 15 is flexibly connected using silica gel, and the outside is sealed using a plastic soft bag to ensure reliable sealing when feeding the punching disc unit 3 in the sealed cabin 8. After the production is completed, it is only necessary to separate the silica gel connection part from the feeder 4, and to seal the soft bag with a heat sealer and then disassemble it, so as to achieve complete sealing disassembly and offline cleaning of the sealed cabin 8, providing a stronger guarantee for dust not to leak out.

[0040] In a preferred embodiment, the suction mechanism 6 is fixed on the bottom plate 17 on the side of the punching disc unit 3, and a suction port is provided at one end of the suction mechanism 6, the suction port faces the work area, and the other end of the suction mechanism 6 passes through the bottom plate 17 and is connected to the negative pressure drive system. Specifically, a connection port is opened on the floor, the suction mechanism 6 is constructed as an L-shaped structure, the bottom of the suction mechanism 6 is fixed on the connection port, and the above-mentioned suction port is provided on the extended end of the bent section of the suction mechanism 6, and the suction port faces the work area of ​​the punching disc unit 3; the negative pressure drive mechanism is connected to the connection port through a dust suction pipe to drive the suction mechanism 6 to suck away excess dust in the shell, while ensuring that the inside of the shell of the sealed cabin 8 is always in a negative pressure state, thereby providing double protection for the dust on the punching disc unit 3 not to leak out.

[0041] It is understandable that the negative pressure state inside the sealed cabin 8 shell in this embodiment is -5 bar, which is the optimal negative pressure state. The pressure difference detection mechanism provided on the negative pressure drive mechanism is interlocked with the operation of the tablet press main controller. When the pressure difference decreases, the tablet press immediately stops and immediately detects the connection state of the vacuum cleaner and the shell connection port. This arrangement prevents the dust in the tablet press chamber 1 from leaking out, protecting the operator from injury.

[0042] In a preferred embodiment, a plurality of spray mechanisms 9 are installed on the lower surface of the upper cover 16. In contrast, a drain port 10 is installed on the bottom plate 17. The process of implementing the online automatic wetting function of the punching disc unit 3 in the shell by using the spray mechanism 9. Specifically, the plurality of spray mechanisms 9 are respectively a plurality of automatically controlled pure water spray balls distributed on the upper cover 16. After the film production of the punching disc unit 3 is completed, the punching disc unit 3 is sprayed and inactivated by the spray ball, and the drain port 10 located on the bottom plate 17 is used to drain the inside of the sealed cabin 8 shell. The spraying process is a pre-cleaning process, which is completely sealed, no cross contamination is generated, and the functions of inactivation and cleaning the punching disc are achieved. After the pre-cleaning process is completed, the sealed cabin 8 and the punching disc unit 3 inside it can be completely removed and transferred to the cleaning room for thorough cleaning. This can effectively avoid the damage to the human body caused by the flying of drug powder when directly cleaning the punching disc.

[0043] It is understandable that it is best to arrange several cleaning stations in the shell of the sealed cabin 8 according to the structural characteristics of the punching disc unit 3, and at least one pure water spray ball is installed on each cleaning station as a spray mechanism 9. After the film production of the punching disc unit 3 is completed, the spray ball is controlled to start according to the set program to realize automatic all-round spraying of pure water inside the shell, so as to wet all parts in the sealed cabin 8 and inactivate the powder on the surface of the parts. The waste water after spraying can be discharged from the drain port 10 on the bottom plate 17. In order to improve the drainage efficiency and drainage balance, drain ports 10 are respectively provided on both sides of the bottom plate 17. The drain port 10 is connected to the wastewater treatment device through a closed pipe to ensure that the entire pre-cleaning process of the sealed cabin 8 is completely sealed, no cross contamination is generated, and the inactivation and cleaning of the punching disc are achieved.

[0044] In a preferred embodiment, a cantilever mechanism 22, a lifting shaft 21 and a mounting seat 20 are also installed in the tablet pressing chamber 1. The mounting seat 20 is fixed on the top of the sealed cabin 8. One end of the lifting shaft 21 is connected to the mounting seat 20 along the axis of the mounting seat 20, and the other end of the lifting shaft 21 is connected to one end of the cantilever mechanism 22, and the other end of the cantilever mechanism 22 is connected with a lifting drive mechanism and a rotating drive mechanism. The mounting seat 20 extends outwardly with at least three connecting arms along the circumferential direction, and the extended end of each connecting arm is respectively fixed to the top of the sealed cabin 8, and the axis of the mounting seat 20 coincides with the axis of the sealed cabin 8 to ensure that the sealed cabin 8 can be balanced in the air when it is lifted. The cantilever mechanism 22 uses the lifting drive mechanism and the rotating drive mechanism to achieve lifting and rotation, so that the sealed cabin 8 can be moved out of the tablet press together with the punching disc unit 3 as a whole through the lifting action and the rotating action, and then the cantilever mechanism 22 is separated from the lifting shaft 21, and the closed punching disc unit 3 is sent to a special cleaning workshop for thorough cleaning.

[0045] Based on the rotary tablet press of the above structure, this embodiment also proposes a cleaning method for the rotary tablet press. The cleaning method includes a pre-cleaning process and a disassembly and cleaning process. The pre-cleaning process is: spraying the punching disc unit 3 inside the shell with the spray mechanism 9. The disassembly and cleaning process is: removing the sealed cabin 8 as a whole from the tablet pressing chamber 1 and cleaning it. The method wets and inactivates and sterilizes all the parts in the sealed cabin 8 through the pre-cleaning process, and then removes the sealed cabin 8 together with the punching disc unit 3 as a whole from the tablet pressing machine through the disassembly and cleaning process, thereby achieving offline inactivation and cleaning.

[0046] It should be understood that in the rotary tablet press and the tablet press cleaning method described in this embodiment, the tablet press is more in line with the requirements of GMP (Good Manufacturing Practice for Pharmaceuticals). During the production process, the parts in contact with the material are completely isolated from the outside world, preventing the leakage of dust generated during the tablet press production process, protecting the operator and the external environment, and is a device suitable for producing anti-cancer, highly allergenic tablet products that are harmful to the normal human body.

[0047] In summary, the rotary tablet press of the present embodiment comprises a tablet press chamber 1, in which a detachable sealed cabin 8 is installed, the sealed cabin 8 comprises a shell, a punching disc unit 3, a suction mechanism 6 and a spray mechanism 9, the punching disc unit 3, the suction mechanism 6 and the spray mechanism 9 are all installed in the shell, the punching disc unit 3 is provided with a workstation area for pressing materials, the suction mechanism 6 is connected to the workstation area, and the spray mechanism 9 is installed around the workstation area. The tablet press seals the punching disc unit 3 as a whole in the shell of the sealed cabin 8, thereby ensuring that the punching disc unit 3 is completely isolated from the outside of the tablet press when the material is pressed, so that the powder generated in the tablet production process is isolated in the sealed cabin 8; the tablet press also uses the spray mechanism 9 in the sealed cabin 8 to pre-clean the punching disc unit 3 after production and in the cleaning and maintenance links, and after pre-cleaning, the sealed cabin 8 is removed from the tablet press chamber 1 and cleaned separately in conjunction with the detachable performance of the sealed cabin 8, thereby avoiding direct contact between the operator and the drug powder in the cleaning and maintenance links.

[0048] The embodiments of the present invention are given for the purpose of illustration and description, and are not intended to be exhaustive or to limit the invention to the disclosed forms. Many modifications and variations will be apparent to those of ordinary skill in the art. The embodiments are selected and described in order to better illustrate the principles and practical applications of the present invention and to enable those of ordinary skill in the art to understand the present invention and thereby design various embodiments with various modifications suitable for specific uses.

Claims

1. A rotary tablet press, comprising a tablet pressing chamber, characterized in that: A detachable sealed cabin is installed in the tablet pressing chamber, and the sealed cabin includes a shell, a punching disc unit, a suction mechanism and a spray mechanism. The punching disc unit, the suction mechanism and the spray mechanism are all installed in the shell. The punching disc unit is provided with a workstation area for pressing materials. The suction mechanism is connected to the workstation area, and the spray mechanism is installed around the workstation area. The shell comprises an upper cover, a bottom plate and a cabin plate, the upper cover and the bottom plate are arranged vertically opposite to each other, and the cabin plates are respectively sealed and connected between the upper cover and the bottom plate; the suction mechanism is fixed to the side of the punching disc unit, one end of the suction mechanism is provided with a suction port, the suction port faces the workstation area, and the other end of the suction mechanism passes through the bottom plate and is connected to the negative pressure driving system, so that the suction mechanism is driven to suck away excess dust in the shell; a plurality of the spray mechanisms are installed on the lower surface of the upper cover; a drain port is installed on the bottom plate; The process of implementing the online automatic wetting function of the punching disc unit in the shell by utilizing the spray mechanism in the sealed cabin, and pre-cleaning the punching disc unit after production and in the cleaning and maintenance links; wherein, several of the spray mechanisms are respectively several automatically controlled pure water spray balls distributed on the upper cover; after the film production of the punching disc unit is completed, the punching disc unit is sprayed and inactivated by the spray balls, and the drainage port located on the bottom plate is used to drain the inside of the sealed cabin shell; after the pre-cleaning process is completed, the sealed cabin and the punching disc unit inside are completely removed and transferred to the cleaning room for thorough cleaning.

2. The rotary tablet press according to claim 1, characterized in that: The upper cover and the bottom plate are coaxially arranged opposite to each other, the punching disc unit is installed between the upper cover and the bottom plate, and the axis of the punching disc unit coincides with the axis of the bottom plate.

3. The rotary tablet press according to claim 1, characterized in that: The sealed cabin also includes a feeding mechanism, which includes a feeder and a hopper. The feeder is installed in the shell and fixed to the side of the punching disc unit. The upper cover is provided with a feeding port. One end of the feeder is connected to the feeding port, and the other end is connected to the work station area. The feeding port is connected to the hopper through a flexible connecting section.

4. The rotary tablet press according to claim 1, characterized in that: A transparent window is arranged on the cabin board.

5. The rotary tablet press according to any one of claims 1 to 4, characterized in that: A cantilever mechanism, a lifting shaft and a mounting seat are also installed in the tablet pressing chamber. The mounting seat is fixed on the top of the sealed cabin, one end of the lifting shaft is connected to the mounting seat along the axis of the mounting seat, the other end of the lifting shaft is connected to one end of the cantilever mechanism, and the other end of the cantilever mechanism is connected to a lifting drive mechanism and a rotating drive mechanism.

6. A method for cleaning a rotary tablet press according to any one of claims 1 to 5, characterized in that: include: Pre-cleaning process: using the spray mechanism to spray the punching disc unit located inside the shell; as well as Disassembly and cleaning process: the sealed cabin is disassembled as a whole from the tablet pressing chamber and cleaned.

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