A liquid transfer device
By designing clamped pipetting equipment, the problems of difficulty in installing and fixing and low efficiency of existing pipetting equipment are solved, and convenient installation and efficient operation of pipettes are achieved.
Patent Information
- Application Number
- CN202010378050.9
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2020-05-07
- Publication Date
- 2024-12-20
- Estimated Expiration
- 2040-05-07
AI Technical Summary
The existing pipetting equipment is not convenient for the installation and fixation of pipettes, and the working efficiency is low.
A pipetting device including a pipette, a pipette, a mounting frame and a chuck mechanism is designed, and the upper plate group and the lower plate group are installed and fixed by clamping. The chuck mechanism can be lifted and lowered to adjust the pipette. the height and position of the liquid to improve the efficiency of liquid absorption and discharge.
It realizes convenient installation and disassembly of pipettes, improves the working efficiency of pipette equipment, and ensures the reliability of installation.
Smart Images

Figure CN111420720B_ABST
Abstract
Description
Technical Field
[0001] The invention relates to the technical field of liquid transfer, and in particular to a liquid transfer device. Background Art
[0002] In the fields of disease control, food safety, and forensic identification, liquid transfer is usually achieved by using a liquid transfer device. However, the existing liquid transfer devices are usually not convenient for the installation and fixation of the pipette, and the working efficiency is low.
[0003] Therefore, a novel liquid transfer device is urgently needed to solve the above-mentioned technical problems. Summary of the invention
[0004] The object of the present invention is to provide a liquid transfer device, which can facilitate the installation and fixation of a pipette and improve work efficiency.
[0005] To achieve the above object, the present invention adopts the following technical solutions:
[0006] A liquid transfer device, comprising:
[0007] A pipette, comprising a pipette body, a gun head and a plunger, wherein the gun head is mounted at the lower end of the pipe body, and the plunger is slidably disposed in the pipe body;
[0008] The liquid transfer mechanism comprises an upper plate group and a lower plate group, wherein the upper end of the plunger is mounted in the upper plate group and the tube body is mounted in the lower plate group;
[0009] Mounting frame;
[0010] Two chuck mechanisms are arranged and installed on the mounting frame in a manner that they can be raised and lowered in the vertical direction. The upper plate group is detachably clamped on the upper chuck mechanism, and the lower plate group is detachably clamped on the lower chuck mechanism. The upper chuck mechanism can drive the plunger to be raised and lowered in the vertical direction through the upper plate group so that the gun tip can absorb or discharge liquid. The lower chuck mechanism can drive the upper chuck mechanism to be raised and lowered in the vertical direction so as to adjust the height of the pipette in the vertical direction.
[0011] As a preferred embodiment of the pipetting device, it also includes a slidably matched chuck rail and a chuck slider, the chuck rail is installed on the mounting frame in the vertical direction, at least two chuck sliders are arranged on the chuck rail in the vertical direction, and each chuck mechanism is connected to at least one chuck slider.
[0012] As a preferred solution of the pipetting device, the chuck mechanism includes a clamping plate, which is vertically movably mounted on the mounting frame, and a clamping groove is provided on the clamping plate, and the upper plate group or the lower plate group can be inserted into the clamping groove.
[0013] As a preferred embodiment of the pipetting device, the clamping groove is a wedge-shaped groove, and the chuck mechanism also includes a wedge block, which is arranged corresponding to the clamping groove and is inserted into the clamping groove in an adjustable position to fix the upper plate group or the lower plate group in the clamping groove.
[0014] As a preferred embodiment of the pipetting device, the chuck mechanism also includes an adjusting member, a first end of the adjusting member is connected to the wedge block, and a second end is connected to the clamping plate, and the adjusting member can drive the wedge block to move along the depth direction of the clamping groove to adjust the insertion position of the wedge block in the clamping groove.
[0015] As a preferred solution of the pipetting device, an adjustment protrusion is provided in the clamping groove, and an adjustment groove extending along the depth direction of the clamping groove is provided on the wedge block, the adjustment groove is sleeved on the adjustment protrusion, the second end of the adjustment member is threadedly connected to the adjustment protrusion, and screwing the first end of the adjustment member can drive the wedge block to move along the depth direction of the clamping groove.
[0016] As a preferred solution of the liquid transfer device, the number of the clamping plates in each of the clamping head mechanisms is two, the two clamping plates are spaced apart and arranged opposite to each other, and the clamping grooves are provided on the inner side walls of the clamping plates.
[0017] As a preferred embodiment of the pipetting device, it also includes a tray, which is movably arranged below the chuck mechanism along a first direction, and a plurality of liquid tanks arranged along the first direction are arranged on the tray, and each of the liquid tanks can be moved to directly below the pipette so that the gun tip can absorb liquid from the liquid tank or discharge liquid into the liquid tank.
[0018] As a preferred embodiment of the pipetting device, it also includes a tray slide, which is arranged below the chuck mechanism, and the tray is slidably arranged on the tray slide along the first direction, and a limiting groove is arranged at the bottom of the tray, and a limiting protrusion which can be retracted along the vertical direction is arranged on the tray slide, and the limiting protrusion can cooperate with the limiting groove to make the liquid trough stay directly below the pipette.
[0019] As a preferred embodiment of the liquid transfer device, it also includes:
[0020] A first driving mechanism, mounted on the mounting frame and having a driving end connected to the chuck mechanism below, so as to drive the chuck mechanism below to rise and fall in a vertical direction;
[0021] The second driving mechanism has a driving end connected to the clamping mechanism above to drive the clamping mechanism above to rise and fall in the vertical direction.
[0022] The beneficial effects of the present invention are:
[0023] The pipetting device provided by the present invention utilizes two chuck mechanisms to detachably clamp the upper plate group and the lower plate group, that is, the upper plate group and the lower plate group are installed and fixed on the pipetting device by a clamping method, thereby realizing the installation and fixation of the pipette, which is not only simple to operate, but also convenient for disassembly of the pipetting mechanism and the pipette, and is also beneficial to ensuring the reliability of the installation; in addition, through the cooperation of the two chuck mechanisms with the upper plate group and the lower plate group, the pipette can also complete the suction and discharge of liquid and the adjustment of the height position, which is beneficial to improving the working efficiency of the pipetting device. BRIEF DESCRIPTION OF THE DRAWINGS
[0024] In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the following briefly introduces the drawings required for use in the description of the embodiments of the present invention. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on the contents of the embodiments of the present invention and these drawings without paying any creative work.
[0025] Figure 1 is a schematic structural diagram of a pipette provided in an embodiment of the present invention;
[0026] Figure 2 is a cross-sectional view of a pipette provided by an embodiment of the present invention;
[0027] Figure 3 yes Figure 2 The enlarged view of point A in the middle;
[0028] Figure 4 is a schematic structural diagram of a liquid transfer mechanism provided by an embodiment of the present invention;
[0029] Figure 5 is a first cross-sectional view of a liquid transfer mechanism provided by an embodiment of the present invention;
[0030] Figure 6 is a second cross-sectional view of the liquid transfer mechanism provided by an embodiment of the present invention;
[0031] Figure 7 is a schematic diagram of the structure of a liquid transfer device provided in an embodiment of the present invention;
[0032] Figure 8 is a schematic diagram of a first partial structure of a liquid transfer device provided in an embodiment of the present invention;
[0033] Fig. 9 is a schematic diagram of a second partial structure of the liquid transfer device provided in an embodiment of the present invention;
[0034] Fig.10 is a schematic diagram of a third partial structure of the liquid transfer device provided in an embodiment of the present invention;
[0035] Fig.11 is a schematic diagram of the bottom structure of a tray provided in an embodiment of the present invention;
[0036] Fig.12 4 is a cross-sectional view of a liquid transfer device provided in an embodiment of the present invention.
[0037] In the figure:
[0038] 1-pipette; 11-tube body; 111-chamber; 112-sealing groove; 12-gun tip; 13-plunger; 14-first sealing ring; 141-sealing lip; 15-sealing space; 16-spacer; 17-second sealing ring;
[0039] 2-pipette mechanism; 21-upper plate assembly; 211-upper fixed plate; 2111-first mounting hole; 212-upper lining plate; 2121-second mounting hole; 2122-third mounting hole; 22-lower plate assembly; 221-lower fixed plate; 2211-step mounting hole; 2212-first rod withdrawal hole; 222-lower lining plate; 2221-fourth mounting hole; 23-plate withdrawal assembly; 231-rod withdrawal; 232-plate withdrawal; 2321-step plate withdrawal hole; 233-reset member; 234-sleeve; 24-adjusting plunger; 25-sealing ring; 26-auxiliary plate; 261-guide hole; 262-second rod withdrawal hole;
[0040] 3-Mounting frame;
[0041] 4-chuck mechanism; 41-clamping plate; 411-clamping groove; 412-adjusting protrusion; 42-wedge block; 421-adjusting groove; 43-adjusting member; 44-connecting plate;
[0042] 51-chuck slide rail; 52-chuck slider;
[0043] 6-tray; 61-liquid tank; 62-limiting member;
[0044] 7-tray slide; 71-guide member;
[0045] 8-first driving mechanism; 81-first driver; 82-first lead screw; 83-first nut seat;
[0046] 9 - second driving mechanism; 91 - second driver; 92 - second lead screw; 93 - second nut seat. DETAILED DESCRIPTION
[0047] In order to make the technical problems solved by the present invention, the technical solutions adopted and the technical effects achieved clearer, the technical solutions of the embodiments of the present invention will be further described in detail below in conjunction with the accompanying drawings. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative work are within the scope of protection of the present invention.
[0048] In the description of the present invention, it should be noted that the terms "center", "up", "down", "left", "right", "vertical", "horizontal", "inside", "outside", etc., indicating the orientation or positional relationship, are based on the orientation or positional relationship shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as limiting the present invention. In addition, the terms "first", "second", etc. are only used for descriptive purposes, or to distinguish different structures or components, and cannot be understood as indicating or implying relative importance. Among them, the terms "first position" and "second position" are two different positions.
[0049] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "connected", and "connected" should be understood in a broad sense, for example, it can be a fixed connection or a detachable connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, and it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.
[0050] like Figure 1-Figure 3 As shown, this embodiment provides a pipette 1, which includes a tube body 11, a gun tip 12, a plunger 13 and a first sealing ring 14. A chamber 111 is provided in the tube body 11. The gun tip 12 is installed at the lower end of the tube body 11 and is connected to the chamber 111. The plunger 13 is slidably arranged in the chamber 111 along the extension direction of the chamber 111 so that the gun tip 12 can absorb or discharge liquid. At least two first sealing rings 14 are arranged between the plunger 13 and the tube body 11, and at least two sealing lips 141 are arranged on the first sealing ring 14, and at least one of the sealing lips 141 abuts against the plunger 13, and at least another sealing lip 141 abuts against the tube body 11.
[0051] The pipette 1 provided in this embodiment is provided with at least two first sealing rings 14 between the plunger 13 and the tube body 11, and at least two sealing lips 141 are provided on the first sealing rings 14. Through the cooperation of the two first sealing rings 14 and the at least two sealing lips 141 in each first sealing ring 14, the sealing between the plunger 13 and the tube body 11 can be effectively ensured, so that the pipette 1 can accurately and quantitatively aspirate and discharge liquid.
[0052] Specifically, in this embodiment, the number of the first sealing rings 14 is two. Of course, in other embodiments, the number of the first sealing rings 14 can also be three or four, etc., which is not limited here.
[0053] Optionally, at least two first sealing rings 14 are one or more of an X-shaped sealing ring, a Y-shaped sealing ring or a V-shaped sealing ring. In this embodiment, the two first sealing rings 14 can be sealing rings of the same type, or can be sealing rings of different types, for example, both first sealing rings 14 are X-shaped sealing rings, or one first sealing ring 14 is an X-shaped sealing ring and the other is a Y-shaped sealing ring, etc. The combination type of the two first sealing rings 14 can be any combination type, which is not limited here. In addition, when it is a Y-shaped sealing ring or a V-shaped sealing ring, the opening direction of the Y-shaped sealing ring or the V-shaped sealing ring is not limited.
[0054] Preferably, if Figure 3 As shown, two adjacent first sealing rings 14 are spaced apart to form a sealed space 15. Further, a lubricating liquid is provided in the sealed space 15. The lubricating liquid in the sealed space 15 can play a role of liquid sealing, thereby facilitating further improving the sealing effect between the plunger 13 and the tube body 11.
[0055] Alternatively, if Figure 3 As shown, the pipette 1 further includes a spacer 16, which is disposed between two adjacent first sealing rings 14 to keep the two adjacent first sealing rings 14 spaced apart. The spacer 16 is provided to help ensure the stability of the size of the sealed space 15, thereby helping to prevent the lubricating liquid in the sealed space 15 from overflowing. Specifically, in this embodiment, the spacer 16 is an annular spacer.
[0056] Specifically, a sealing groove 112 is provided at the upper end of the tube body 11, and at least two first sealing rings 14 are disposed in the sealing groove 112. The sealing groove 112 is conducive to preventing the first sealing ring 14 from being displaced, and ensuring the stability of the position of the first sealing ring 14.
[0057] Preferably, if Figure 2As shown, the pipette 1 also includes a second sealing ring 17, and at least two second sealing rings 17 are arranged between the gun head 12 and the tube body 11. The second sealing ring 17 is conducive to ensuring the sealing between the gun head 12 and the tube body 11. Specifically, in this embodiment, the second sealing ring 17 is an O-ring. Further, in this embodiment, the number of the second sealing rings 17 is two.
[0058] Optionally, the lower end of the tube body 11 is provided with an outer conical surface, and the upper end of the gun head 12 is provided with an inner conical surface, and the outer conical surface can fit with the inner conical surface. By providing the outer conical surface and the inner conical surface, the insertion and matching of the gun head 12 and the tube body 11 can be facilitated.
[0059] like Figure 4-Figure 6 As shown, this embodiment also provides a pipetting mechanism 2 for installing the above-mentioned pipette 1, and the pipetting mechanism 2 includes an upper plate group 21, a lower plate group 22 and a retracting plate assembly 23. The upper end of the plunger 13 is installed in the upper plate group 21. The tube body 11 is installed in the lower plate group 22. The retracting plate assembly 23 includes a retracting rod 231 and a retracting plate 232. The first end of the retracting rod 231 can pass through the lower plate group 22 in a vertical direction and the second end of the retracting rod 231 is connected to the retracting plate 232, and the retracting plate 232 can abut against the upper end surface of the gun head 12. The upper plate group 21 can drive the plunger 13 to move upward so that the gun head 12 absorbs liquid. The upper plate group 21 can drive the plunger 13 to move downward so that the gun head 12 discharges liquid. The upper plate assembly 21 continues to move downward to abut against the first end of the retracting rod 231 , and the retracting rod 231 drives the retracting plate 232 to push the upper end surface of the gun head 12 downward, so that the gun head 12 is separated from the tube body 11 .
[0060] When liquid needs to be absorbed, the lower plate group 22 is fixed, which is equivalent to the tube body 11 remaining stationary, and the upper plate group 21 alone drives the plunger 13 to move upward, so that the gun head 12 absorbs liquid; when liquid needs to be discharged, the lower plate group 22 is fixed, and the upper plate group 21 drives the plunger 13 to move downward (at this time, the upper plate group 21 and the withdrawal rod 231 are not in contact), so that the gun head 12 discharges liquid; when the gun head 12 needs to be removed from the tube body 11, the lower plate group 22 is fixed, and the upper plate group 21 continues to move downward and push the withdrawal rod 231, so that the withdrawal rod 231 drives the withdrawal plate 232 to move downward and pushes the gun head 12 to move downward, thereby realizing the separation of the gun head 12 from the tube body 11.
[0061] The pipetting mechanism 2 provided in the present embodiment installs the upper end of the plunger 13 in the upper plate group 21, and installs the tube body 11 in the lower plate group 22, which not only ensures the reliability of the installation, but also enables the plunger 13 and the tube body 11 to be disassembled and assembled separately. When the pipette 1 needs to be repaired, such as replacing the sealing ring, there is no need to take the entire pipette 1 out of the pipetting mechanism 2, and only the lower plate group 22 needs to be removed separately, thereby simplifying the disassembly and assembly process and making the replacement of the sealing ring simpler and more convenient; in addition, through the cooperation of the upper plate group 21 and the lower plate group 22 with the retracting plate assembly 23, the gun head 12 can be smoothly separated from the tube body 11, which is beneficial to improving the working efficiency of the pipetting mechanism 2.
[0062] In this embodiment, a plurality of pipettes 1 are installed on the pipetting mechanism 2 in a rectangular array.
[0063] Specifically, in this embodiment, there are four retracting rods 231, which are respectively located at four corners of the retracting plate 232. Of course, in other embodiments, the number and distribution positions of the retracting rods 231 can be adjusted according to actual needs, which is not limited here.
[0064] Optionally, a buffer is provided at the upper end of the retracting rod 231 to prevent a hard collision between the upper plate assembly 21 and the retracting rod 231. Specifically, the buffer may be a rubber pad or the like.
[0065] like Figure 5 As shown, the upper plate group 21 provided in this embodiment includes an upper fixing plate 211 and an upper lining plate 212. An upper mounting groove with an opening facing upward is provided on the upper fixing plate 211, and a first mounting hole 2111 is provided at the bottom of the upper mounting groove. The plunger 13 is inserted into the first mounting hole 2111, and the flange at the upper end of the plunger 13 can abut against the inner bottom surface of the upper mounting groove. The upper lining plate 212 is installed in the upper mounting groove, and a second mounting hole 2121 is provided on the upper lining plate 212. The second mounting hole 2121 is coaxial with the first mounting hole 2111, and the flange at the upper end of the plunger 13 is arranged in the second mounting hole 2121. The flange at the upper end of the plunger 13 is clamped between the upper fixing plate 211 and the upper lining plate 212, so that the upper plate group 21 can drive the plunger 13 to move up and down.
[0066] In the present embodiment, the pipetting mechanism 2 further comprises an adjusting plunger 24, and a third mounting hole 2122 is provided on the upper lining plate 212, and the third mounting hole 2122 is coaxial with and communicated with the second mounting hole 2121, and the adjusting plunger 24 can be inserted into the third mounting hole 2122 and press against the top of the plunger 13, so that the flange of the plunger 13 abuts against the inner bottom surface of the upper mounting groove. Specifically, in the present embodiment, the adjusting plunger 24 is threadedly matched with the third mounting hole 2122, and the adjusting plunger 24 can be screwed to press against the top of the plunger 13, and the flange of the plunger 13 is tightly fitted against the inner bottom surface of the upper mounting groove, so as to prevent the existence of an installation gap between the two, and ensure the installation accuracy of the plunger 13.
[0067] The lower plate assembly 22 provided in this embodiment includes a lower fixing plate 221 and a lower lining plate 222. The lower fixing plate 221 is provided with a lower mounting groove with an opening facing downward, and a step mounting hole 2211 is provided at the top of the lower mounting groove. The flange at the upper end of the tube body 11 is arranged in the step mounting hole 2211 and the top surface of the flange abuts against the step surface of the step mounting hole 2211, and the plunger 13 can pass through the step mounting hole 2211 and be inserted into the tube body 11. The lower lining plate 222 is installed in the lower mounting groove, and a fourth mounting hole 2221 is provided on the lower lining plate 222. The fourth mounting hole 2221 is coaxial with the step mounting hole 2211. The tube body 11 is penetrated in the fourth mounting hole 2221 and the bottom surface of the upper end flange abuts against the lower lining plate 222. The flange lower fixing plate 221 at the upper end of the tube body 11 and the lower lining plate 222 are between each other, so that the lower plate assembly 22 can drive the tube body 11 to move up and down.
[0068] Preferably, the pipetting mechanism 2 provided in this embodiment further includes a sealing ring 25, which is disposed between the lower fixing plate 221 and the tube body 11. The sealing ring 25 is conducive to ensuring the sealing between the lower fixing plate 221 and the tube body 11. Optionally, the sealing ring 25 is an O-ring.
[0069] The pipetting mechanism 2 provided in this embodiment further includes an auxiliary plate 26, which is connected to the lower fixing plate 221 and is located below the lower fixing plate 221. The auxiliary plate 26 is provided with a guide hole 261, and the tube body 11 is passed through the guide hole 261. The guide hole 261 is helpful to prevent the tube body 11 from shaking during the lifting process, and ensure the accuracy of the lifting path of the tube body 11.
[0070] Specifically, in this embodiment, the top surface of the auxiliary plate 26 abuts against the bottom surface of the lower lining plate 222 to fix the lower lining plate 222 in the lower mounting groove, thereby ensuring the stability and reliability of the installation of the lower lining plate 222.
[0071] like Figure 6As shown, preferably, the plate retracting assembly 23 further includes a reset member 233, which is sleeved on the retracting rod 231 and can push the retracting rod 231 to reset. The reset members 233 are arranged one-to-one with the retracting rod 231. In this embodiment, the number of reset members 233 is four. Specifically, in this embodiment, the reset member 233 is a reset spring.
[0072] Further, the lower fixed plate 221 is provided with a first rod withdrawal hole 2212, and the auxiliary plate 26 is provided with a second rod withdrawal hole 262. The first rod withdrawal hole 2212 is coaxial with the second rod withdrawal hole 262. The rod withdrawal 231 can be lifted and lowered in the first rod withdrawal hole 2212 and the second rod withdrawal hole 262 in the vertical direction. The reset member 233 is sleeved on the rod withdrawal 231, and the upper end of the reset member 233 abuts against the flange at the upper end of the rod withdrawal 231, and the lower end abuts against the bottom surface of the second rod withdrawal hole 262. The reset member 233 can push the flange at the upper end of the rod withdrawal 231 upward to reset the rod withdrawal 231 upward. In this embodiment, the reset member 233 is installed in the second rod withdrawal hole 262 on the auxiliary plate 26. In other embodiments, the reset member 233 can also be installed on the lower fixed plate 221, which is not limited here, as long as the rod withdrawal 231 can be reset.
[0073] Alternatively, if Figure 5 As shown, the retreat plate 232 is provided with a stepped retreat hole 2321, and the stepped surface of the stepped retreat hole 2321 can abut against the upper end surface of the gun head 12 to push the gun head 12 away from the tube body 11. The stepped surface of the stepped retreat hole 2321 can be in uniform contact with the circumference of the upper end surface of the gun head 12, so that the upper end surface of the gun head 12 is uniformly stressed, which is conducive to the gun head 12 being smoothly separated from the tube body 11.
[0074] It should be noted that, in this embodiment, since the plurality of pipettes 1 are arranged in a rectangular array on the pipetting mechanism 2, the various mounting holes on the upper plate group 21, the lower plate group 22, the auxiliary plate 26 and the retracting plate 232 are also arranged in a rectangular array.
[0075] Optionally, in this embodiment, numbers are provided on the edge of the bottom surface of the withdrawal plate 232 , and the numbers are provided in one-to-one correspondence with the stepped withdrawal holes 2321 in the outermost circle of the rectangular array, so as to identify the row and column where the pipette 1 is located.
[0076] like Figure 4-Figure 6 As shown, the plate retracting assembly 23 provided in this embodiment further includes a sleeve 234, which is sleeved on the lower end of the retracting rod 231, and the upper end of the sleeve 234 can abut against the bottom surface of the auxiliary plate 26 to limit the upward movement of the retracting rod 231. The sleeves 234 are arranged one-to-one with the retracting rod 231, and in this embodiment, the number of sleeves 234 is four.
[0077] like Figure 7-Figure 9 Combination Figure 1 and Figure 4 As shown, this embodiment also provides a pipetting device, including a pipette 1, a pipetting mechanism 2, a mounting frame 3 and two chuck mechanisms 4. The pipette 1 includes a tube body 11, a gun head 12 and a plunger 13, the gun head 12 is installed at the lower end of the tube body 11, and the plunger 13 is slidably arranged in the tube body 11. The pipetting mechanism 2 includes an upper plate group 21 and a lower plate group 22, the upper end of the plunger 13 is installed in the upper plate group 21, and the tube body 11 is installed in the lower plate group 22. The two chuck mechanisms 4 are arranged and installed on the mounting frame 3 in a manner that they can be raised and lowered in the vertical direction. The upper plate group 21 is detachably clamped on the upper chuck mechanism 4, and the lower plate group 22 is detachably clamped on the lower chuck mechanism 4. The upper chuck mechanism 4 can drive the plunger 13 to be raised and lowered in the vertical direction through the upper plate group 21 so that the gun tip 12 can absorb or discharge liquid. The lower chuck mechanism 4 can drive the upper chuck mechanism 4 to be raised and lowered in the vertical direction so as to adjust the height of the pipette 1 in the vertical direction.
[0078] When it is necessary to aspirate, the lower chuck mechanism 4 first drives the upper chuck mechanism 4 to move in the vertical direction to adjust the pipette 1 as a whole to the aspiration position, and then the lower chuck mechanism 4 is fixed, which is equivalent to keeping the lower plate group 22 and the tube body 11 stationary, and the upper chuck mechanism 4 drives the plunger 13 to move upward through the upper plate group 21 to make the gun head 12 aspirate; when it is necessary to discharge, the lower chuck mechanism 4 first drives the upper chuck mechanism 4 to move in the vertical direction to adjust the pipette 1 as a whole to the discharge position, and then The lower chuck mechanism 4 is fixed, and the upper chuck mechanism 4 drives the upper plate group 21 and the plunger 13 to move downward (at this time, the upper plate group 21 is not in contact with the retracting rod 231), so that the gun tip 12 discharges the liquid; when the gun tip 12 needs to be removed from the tube body 11, the lower chuck mechanism 4 is fixed, and the upper chuck mechanism 4 continues to move downward and causes the upper plate group 21 to push the retracting rod 231, and at the same time, the retracting rod 231 drives the retracting plate 232 to move downward and pushes the gun tip 12 to move downward, thereby realizing the separation of the gun tip 12 from the tube body 11.
[0079] The pipetting device provided in the present embodiment utilizes two chuck mechanisms 4 to detachably clamp the upper plate group 21 and the lower plate group 22, that is, a clamping method is adopted to realize the installation and fixation of the upper plate group 21 and the lower plate group 22 on the pipetting device, and then realize the installation and fixation of the pipette 1. It is not only simple to operate, but also convenient for the disassembly of the pipetting mechanism 2 and the pipette 1, and it is also beneficial to ensure the reliability of the installation of the upper plate group 21 and the lower plate group 22; in addition, through the cooperation of the two chuck mechanisms 4 with the upper plate group 21 and the lower plate group 22, the pipette 1 can also complete the suction and discharge of liquid and the adjustment of the height position, which is beneficial to improve the working efficiency of the pipetting device.
[0080] Preferably, if Fig. 9As shown, the clamping mechanism 4 includes a clamping plate 41, which is vertically movably mounted on the mounting frame 3, and a clamping groove 411 is provided on the clamping plate 41, and the upper plate group 21 or the lower plate group 22 can be inserted into the clamping groove 411. Specifically, in this embodiment, the upper fixing plate 211 and the lower fixing plate 221 are both provided with a flange, and the flange can be inserted into the clamping groove 411.
[0081] In this embodiment, there are two clamping plates 41 in each clamping mechanism 4, and the two clamping plates 41 are spaced apart and arranged opposite to each other, and the clamping groove 411 is provided on the inner side wall of the clamping plate 41. The two clamping grooves 411 on the two clamping plates 41 can clamp the two ends of the upper plate group 21 or the lower plate group 22 respectively to ensure the stability of clamping and avoid interference between the clamping plates 41 and the pipette 1. Of course, in other embodiments, a clamping plate 41 can also be provided in each clamping mechanism 4, and a through-shaped clamping groove 411 can be provided on the clamping plate 41, in which case the clamping function can be achieved by clamping the middle of the upper plate group 21 or the lower plate group 22.
[0082] In this embodiment, the clamping groove 411 is a wedge-shaped groove, and the clamping head mechanism 4 further includes a wedge block 42, which is arranged corresponding to the clamping groove 411 and inserted in the clamping groove 411 in an adjustable position, so that the upper plate group 21 or the lower plate group 22 is fixed in the clamping groove 411. By adjusting the insertion depth of the wedge block 42 in the clamping groove 411, it is not only helpful to prevent the upper plate group 21 or the lower plate group 22 from leaving a movable gap between the groove surface of the clamping groove 411, so that the upper plate group 21 or the lower plate group 22 is stably clamped in the clamping groove 411, but also helpful to remove the upper plate group 21 or the lower plate group 22 from the clamping groove 411.
[0083] Specifically, in this embodiment, each clamping plate 41 is provided with a clamping groove 411 , that is, the number of the clamping grooves 411 is four, and the number of the wedge blocks 42 corresponding to the clamping grooves 411 is also four.
[0084] The clamping mechanism 4 provided in this embodiment further includes an adjusting member 43, a first end of which is connected to the wedge block 42, and a second end of which is connected to the clamping plate 41, and the adjusting member 43 can drive the wedge block 42 to move along the depth direction of the clamping groove 411 to adjust the insertion position of the wedge block 42 in the clamping groove 411. That is, the insertion position of the wedge block 42 in the clamping groove 411 is adjusted by the adjusting member 43.
[0085] Preferably, an adjusting protrusion 412 is provided in the clamping groove 411, and an adjusting groove 421 extending in the depth direction of the clamping groove 411 is provided on the wedge block 42, and the adjusting groove 421 is sleeved on the adjusting protrusion 412. The second end of the adjusting member 43 is threadedly connected with the adjusting protrusion 412, and screwing the first end of the adjusting member 43 can drive the wedge block 42 to move in the depth direction of the clamping groove 411. By screwing the adjusting member 43, the adjusting member 43 can be moved relative to the adjusting protrusion 412 in the depth direction of the clamping groove 411, thereby driving the wedge block 42 to move, so that the wedge block 42 fixes the upper plate group 21 or the lower plate group 22 in the clamping groove 411.
[0086] Preferably, if Figure 8 As shown, the liquid transfer device provided in this embodiment also includes a chuck slide rail 51 and a chuck slider 52 that are slidably matched. The chuck slide rail 51 is installed on the mounting frame 3 in the vertical direction. At least two chuck sliders 52 are arranged on the chuck slide rail 51 in the vertical direction. Each chuck mechanism 4 is connected to at least one chuck slider 52. The cooperation of the chuck slide rail 51 and the chuck slider 52 is conducive to ensuring the stability of the lifting and lowering of the chuck mechanism 4 and the accuracy of the lifting and lowering path. In addition, in this embodiment, the two chuck mechanisms 4 adopt a common rail design, that is, they share the same chuck slide rail 51, which is conducive to simplifying the structure of the device, improving the compactness of the structure, and reducing the cost of the device.
[0087] Specifically, in this embodiment, two chuck slide rails 51 are arranged in parallel and at intervals, and two chuck sliders 52 are arranged on each chuck slide rail 51, that is, the number of the chuck sliders 52 is four, and the chuck sliders 52 are connected to the clamping plates 41 in a one-to-one correspondence.
[0088] like Figure 7 , Figure 8 as well as Fig.10 As shown, the pipetting device provided in this embodiment also includes a tray 6, and the tray 6 is movably arranged below the chuck mechanism 4 along a first direction. A plurality of liquid grooves 61 arranged along the first direction are arranged on the tray 6, and each liquid groove 61 can be moved to directly below the pipette 1, so that the gun tip 12 can absorb liquid from the liquid groove 61 or discharge liquid into the liquid groove 61. Specifically, in this embodiment, the number of liquid grooves 61 is three. When the gun tip 12 completes absorbing liquid in the first liquid groove 61, the lower chuck mechanism 4 drives the upper chuck mechanism 4 to move upward to prevent the tray 6 from interfering with the pipette 1 when moving, and then pushes the tray 6 to move the second liquid groove 61 to below the gun tip 12, and then the gun tip 12 can discharge liquid into the second liquid groove 61. It should be pointed out that in this embodiment, Figure 7 The structure at the bottom of the middle tray 6 is Figure 8 The structure of the bottom of the middle tray 6 is slightly different, but both are provided with a liquid tank 61 , which can cooperate with the pipette 1 to complete the transfer.
[0089] The edge of the tray 6 provided in this embodiment is provided with numbers, and the numbers are used to identify the row and column where the pipette 1 is located.
[0090] The liquid transfer device provided in this embodiment also includes a tray slide 7, which is arranged below the chuck mechanism 4, and the tray 6 is slidably arranged on the tray slide 7 along the first direction, and a limiting groove is arranged at the bottom of the tray 6, and a limiting protrusion that can be extended and retracted along the vertical direction is arranged on the tray slide 7, and the limiting protrusion can cooperate with the limiting groove to make the liquid tank 61 stay directly below the pipette 1. The limiting protrusion can adopt a structure in which a ball and a spring cooperate, and the ball is arranged at the top of the spring. When the tray 6 needs to move, pushing the tray 6 can compress the spring, so that the tray 6 can move smoothly. When the tray 6 moves into place, the ball falls into the limiting groove, and the spring stretches, so that the tray 6 stays directly below the pipette 1.
[0091] In the present embodiment, the tray 6 is moved by manual pushing. Of course, in other embodiments, the movement of the tray 6 may also be achieved by structures such as an electric slide, which is not limited here.
[0092] Alternatively, if Fig.11 As shown, a limiting member 62 is provided at the bottom of the tray 6, and a guide member 71 cooperating with the limiting member 62 is provided on the tray slide 7. When the tray 6 is disassembled, the limiting member 62 is rotated 90° so that the limiting member 62 can pass through the inner hole of the guide member 71, thereby replacing the tray 6; after replacement, the limiting member 62 is rotated in the opposite direction by 90° so that the limiting member 72 cannot pass through the inner hole of the guide member 71, thereby achieving limitation.
[0093] like Figure 8 Combination Fig.12 As shown, the liquid transfer device provided in this embodiment further includes a first driving mechanism 8 and a second driving mechanism 9. The first driving mechanism 8 is mounted on the mounting frame 3 and its driving end is connected to the lower chuck mechanism 4 to drive the lower chuck mechanism 4 to rise and fall in the vertical direction. The driving end of the second driving mechanism 9 is connected to the upper chuck mechanism 4 to drive the upper chuck mechanism 4 to rise and fall in the vertical direction.
[0094] Specifically, in this embodiment, Fig.12 As shown, the first driving mechanism 8 includes a first driver 81, a first lead screw 82 and a first nut seat 83. The first driver 81 is installed on the mounting frame 3. The first lead screw 82 extends in the vertical direction and is transmission-connected with the driving end of the first driver 81. The first nut seat 83 is fixedly installed on the connecting plate 44 of the lower chuck mechanism 4. The first driver 81 can drive the first lead screw 82 to rotate, and the first nut seat 83 drives the lower chuck mechanism 4 to move in the vertical direction.
[0095] Furthermore, the first lead screw 82 and the driving end of the first driver 81 are connected to each other through a transmission belt and a transmission wheel.
[0096] like Fig.12 As shown, in this embodiment, the second driving mechanism 9 includes a second driver 91, a second lead screw 92 and a second nut seat 93. The second driver 91 is fixedly mounted on the connecting plate 44 of the upper chuck mechanism 4. The second lead screw 92 extends in the vertical direction and is in driving connection with the driving end of the second driver 91. The second nut seat 93 is fixedly mounted on the connecting plate 44 of the lower chuck mechanism 4. The second driver 91 can drive the second lead screw 92 to rotate, and the second lead screw 92 drives the upper chuck mechanism 4 and the second driver 91 to move in the vertical direction. That is, the first lead screw 82 in the first driving mechanism 8 remains in position, while the first nut seat 83 will rise and fall in the vertical direction. The second nut seat 93 in the second driving mechanism 9 remains in position, while the second lead screw 92 will rise and fall in the vertical direction.
[0097] Note that the above are only preferred embodiments of the present invention and the technical principles used. Those skilled in the art will understand that the present invention is not limited to the specific embodiments described herein, and that various obvious changes, readjustments and substitutions can be made by those skilled in the art without departing from the scope of protection of the present invention. Therefore, although the present invention has been described in more detail through the above embodiments, the present invention is not limited to the above embodiments, and may include more other equivalent embodiments without departing from the concept of the present invention, and the scope of the present invention is determined by the scope of the appended claims.
Claims
1. A liquid transfer device, characterized in that: include: A pipette (1) comprising a tube body (11), a gun head (12) and a plunger (13), wherein the gun head (12) is mounted at the lower end of the tube body (11), and the plunger (13) is slidably disposed in the tube body (11); The liquid transfer mechanism (2) comprises an upper plate group (21) and a lower plate group (22), wherein the upper end of the plunger (13) is mounted in the upper plate group (21), and the tube body (11) is mounted in the lower plate group (22); Mounting frame (3); Two chuck mechanisms (4) are arranged and mounted on the mounting frame (3) in a manner that they can be raised and lowered in the vertical direction; the upper plate group (21) is detachably clamped on the upper chuck mechanism (4), and the lower plate group (22) is detachably clamped on the lower chuck mechanism (4); the upper chuck mechanism (4) can drive the plunger (13) to rise and fall in the vertical direction through the upper plate group (21) so that the gun head (12) can absorb or discharge liquid; the lower chuck mechanism (4) can drive the upper chuck mechanism (4) to rise and fall in the vertical direction so as to adjust the height of the pipette (1) in the vertical direction; It also comprises a chuck slide rail (51) and a chuck slider (52) that are slidably matched, the chuck slide rail (51) being mounted on the mounting frame (3) in a vertical direction, at least two chuck sliders (52) being arranged in a vertical direction on the chuck slide rail (51), and each of the chuck mechanisms (4) being connected to at least one of the chuck sliders (52); The clamping mechanism (4) comprises a clamping plate (41), the clamping plate (41) being mounted on the mounting frame (3) in a liftable manner in a vertical direction, the clamping plate (41) being provided with a clamping groove (411), and the upper plate group (21) or the lower plate group (22) being capable of being inserted into the clamping groove (411); The clamping groove (411) is a wedge-shaped groove, and the clamping head mechanism (4) further comprises a wedge block (42), wherein the wedge block (42) is arranged corresponding to the clamping groove (411) and is inserted into the clamping groove (411) in an adjustable position, so that the upper plate group (21) or the lower plate group (22) is fixed in the clamping groove (411).
2. The liquid transfer device according to claim 1, characterized in that The clamping head mechanism (4) further comprises an adjusting member (43), wherein a first end of the adjusting member (43) is connected to the wedge block (42), and a second end of the adjusting member (43) is connected to the clamping plate (41), and the adjusting member (43) can drive the wedge block (42) to move along the depth direction of the clamping groove (411) to adjust the insertion position of the wedge block (42) in the clamping groove (411).
3. The liquid transfer device according to claim 2, characterized in that: An adjusting protrusion (412) is provided in the clamping groove (411), and an adjusting groove (421) extending in the depth direction of the clamping groove (411) is provided on the wedge block (42), and the adjusting groove (421) is sleeved on the adjusting protrusion (412), and the second end of the adjusting member (43) is threadedly connected to the adjusting protrusion (412), and screwing the first end of the adjusting member (43) can drive the wedge block (42) to move in the depth direction of the clamping groove (411).
4. The liquid transfer device according to claim 1, characterized in that: The number of the clamping plates (41) in each clamping head mechanism (4) is two, the two clamping plates (41) are spaced apart and arranged opposite to each other, and the clamping groove (411) is provided on the inner side wall of the clamping plate (41).
5. The liquid transfer device according to claim 1, characterized in that: It also includes a tray (6), the tray (6) being movably arranged below the clamping mechanism (4) along a first direction, and the tray (6) being provided with a plurality of liquid grooves (61) arranged along the first direction, and each of the liquid grooves (61) being capable of moving to the position directly below the pipette (1) so that the gun tip (12) can absorb liquid from the liquid groove (61) or discharge liquid into the liquid groove (61).
6. The liquid transfer device according to claim 5, characterized in that: The tray slide (7) is arranged below the chuck mechanism (4); the tray (6) is slidably arranged on the tray slide (7) along the first direction; a limiting groove is arranged at the bottom of the tray (6); and a limiting protrusion which is retractable along the vertical direction is arranged on the tray slide (7); the limiting protrusion can cooperate with the limiting groove so that the liquid tank (61) stays directly below the pipette (1).
7. The liquid transfer device according to claim 1, characterized in that: Also includes: A first driving mechanism (8) is mounted on the mounting frame (3) and a driving end thereof is connected to the chuck mechanism (4) below so as to drive the chuck mechanism (4) below to move up and down in a vertical direction; A second driving mechanism (9) has a driving end connected to the upper clamping mechanism (4) to drive the upper clamping mechanism (4) to move up and down in a vertical direction.
Citation Information
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