An emulsified bacteria evaporation system

Abstract

The present invention discloses an emulsified bacteria evaporation system, including an emulsification section, a bacteria section, an evaporation section, a quantitative transfer filtration section and a storage section connected by pipelines, the emulsification section includes an aqueous phase tank and an organic solvent tank, the two are mixed in proportion to the emulsification tank; the homogenization section is a circulating bacteria section, including a first bacteria tank and a second bacteria tank in parallel, and also includes a bacteria machine, a buffer tank and a coil preheating structure are sequentially arranged between the bacteria section and the evaporation section; the evaporation section includes at least two scraper film evaporators, and the scraper film evaporators are connected in series and / or in parallel under the action of pipelines and valves. The present invention adopts a circulating bacteria mechanism to overcome the problem of enlarged particle size caused by insufficient bacteria, and adopts a new type of evaporation, equipped with buffer preheating to ensure the evaporation effect, and at the same time, multiple filtering processes are performed before the finished product, and the product safety is high.

Description

Technical Field

[0001] The invention relates to the field of medicine preparation, and in particular to an emulsified bacteria evaporation system. Background Art

[0002] In the process of drug preparation, mixed emulsification and bacterial preparation is a necessary process. However, in the current preparation system, insufficient bacterial preparation process can easily lead to larger particle size, affecting the preparation effect.

[0003] At the same time, the evaporator is an important component in the preparation process. The scraper film evaporator is mainly used in the pharmaceutical process. The scraper spreads the material on the inner wall of the evaporator cylinder and separates the organic solvent or volatile solvent efficiently and stably through heat exchange.

[0004] The function of the scraper is to dilute the material on the inner wall of the cylinder. The current material feeding method is to directly open a feed port on the cylinder so that the scraper can directly dilute the material. However, this feeding method has an obvious feeding area and cannot achieve uniform feeding, which will affect the separation effect of the evaporator.

[0005] In addition, the scraper structure currently on the market is mainly an integrated rigid scraper fixed on the rotor. However, in this solution, the distance between the scraper and the cylinder wall is fixed, and the scope of application is limited. However, the material is affected by many factors during the evaporation process, such as residence time, self-viscosity, etc., and the thickness distribution is different.

[0006] Moreover, some raw materials are prone to surface expansion and formation of bubbles after being processed at the front end and then entering the vacuum heating environment, which then escape from the vacuum pipe and cause waste.

[0007] Therefore, a new drug preparation system needs to be developed. Summary of the invention

[0008] In order to solve the above problems, the present invention provides an emulsified bacteria evaporation system, which adopts a circulating bacteria mechanism to overcome the problem of enlarged particle size caused by insufficient bacteria. It also adopts a new type of evaporation and is equipped with buffer preheating to ensure the evaporation effect. At the same time, it has multiple filtering processes before the finished product, and the product is highly safe.

[0009] In addition, the evaporator uses a distributor to achieve uniform feeding of the material to the entire cylinder wall in an overflow manner, and the material is discharged continuously and evenly, which is convenient for subsequent scraper thinning and ensures that the separation effect of the evaporator is stable and efficient.

[0010] At the same time, the connection of the distributor is convenient and fast, with high stability and good sealing performance, which can ensure that the vacuum state in the evaporator is not affected.

[0011] The scraper cage structure adopts a segmented scraper structure, which moves up and down and swings centrifugally, allowing each scraper section to self-adjust the distance from the cylinder wall according to the thickness of the material. Under the action of centrifugal force, it is pressed against the cylinder wall more thinly to increase the evaporation efficiency.

[0012] What's more, the defoamer breaks up the foam to avoid the slow descent of materials due to the accumulation of foam, and avoids the waste of raw materials.

[0013] In order to achieve the above object, the technical solution adopted by the present invention is:

[0014] An emulsified bacterial evaporation system comprises an emulsification section, a bacterial preparation section, an evaporation section, a quantitative transfer filtration section and a storage section connected by pipelines;

[0015] The emulsification section includes a water phase tank and an organic solvent tank, which are mixed in proportion to the emulsification tank;

[0016] The bacterial production section is a circulating bacterial production section, including a first bacterial production tank and a second bacterial production tank connected in parallel, and also includes a bacterial production machine;

[0017] A buffer tank and a coil preheating structure are provided in sequence between the bacterial production section and the evaporation section;

[0018] The evaporation section comprises at least two scraped film evaporators, and the scraped film evaporators are connected in series and / or in parallel under the action of pipelines and valves;

[0019] The quantitative transfer filtration section includes a quantitative tank, the rear end of which is connected to a first transfer tank via a first filter in parallel, a second filter is provided in series between the first transfer tank and the second transfer tank, and a sterile filter is provided between the second transfer tank and the storage tank of the storage section;

[0020] The scraper film evaporator comprises an evaporator cylinder and a driving structure arranged on the upper side of the evaporator cylinder, a scraper cage structure is arranged in the evaporator cylinder, the upper side of which is connected to the driving structure, and the lower side is limited by the bearing on the lower head at the bottom of the evaporator cylinder, a discharge port is arranged on the lower side of the lower head, a water cavity is arranged on the side wall of the evaporator cylinder, and a water inlet and a water outlet are arranged at the bottom and the top of the water cavity, an insulation layer is arranged on the outside of the water cavity, a cleaning port and a vacuum interface are arranged on the cylinder wall of the evaporator cylinder on the upper side of the scraper cage structure, and a feeding structure is arranged on the cylinder wall of the evaporator cylinder adjacent to the scraper cage structure;

[0021] The driving structure includes a motor, a driving chamber, a coupling and a single-end mechanical seal. The motor flange is fixed to the top of the driving chamber and acts on the coupling. The bottom of the driving chamber is fixed to the upper flange of the evaporator cylinder. The coupling is fixed to the scraper cage structure.

[0022] The scraper cage structure includes a central rotating shaft and an upper chuck and a lower chuck fixed to the upper and lower sides of the central rotating shaft. At least three scraper fixing shafts are arranged between the upper chuck and the lower chuck. The scraper fixing shaft is overlapped and sleeved with a plurality of hollow cylindrical scrapers, and there is an offset between the cylindrical scrapers and the scraper fixing shaft. The edge of the cylindrical scraper protrudes from the upper chuck and the lower chuck. The central rotating shaft passes through the evaporator cylinder and is fixed to the coupling, and the single-end mechanical seal acts at the flange connection.

[0023] The distance between the cylindrical scraper at the top and the upper chuck is 2-5 mm, and the scraper fixing shaft is arranged in 4 numbers, and the upper chuck and the lower chuck are evenly divided at the periphery;

[0024] The feed structure includes a distributor which is arranged between the upper cylinder and the lower cylinder of the evaporator cylinder and is sealed and fixed. The first connecting flange at the bottom of the upper cylinder and the second connecting flange at the top of the lower cylinder are used for upper and lower limit fixation of the distributor. The circumferential side wall of the distributor is evenly divided with at least three feed ports. The upper side surface of the distributor is provided with a first connecting stop, a feed trough and an overflow weir from the outside to the inside, and the lower side surface is provided with a second connecting stop. The middle part is a through discharge port. The edge of the discharge port is flush with the inner wall of the upper cylinder and the lower cylinder, and the feed port is connected to the internal feed outlet arranged in the feed trough.

[0025] Furthermore, the central rotating shaft is provided with a defoamer on the upper side of the upper chuck, and the defoamer is a symmetrical paddle structure, and the paddles thereof are evenly distributed with conical through holes.

[0026] Furthermore, sealing rings are provided inside the first connection stop and the second connection stop for sealing, and overflow notches are evenly distributed on the overflow weir.

[0027] Furthermore, the number of the feed ports is 4, and the edge of the distributor is equally divided with connection holes, and connecting bolts pass through the connection holes to fix the distributor to the first connecting flange and the second connecting flange.

[0028] Furthermore, an angular contact bearing is provided in the driving cavity and acts on the central rotating shaft at the lower side of the coupling.

[0029] Furthermore, the bacterial preparation machine is a high-pressure microfluidic bacterial preparation machine.

[0030] In summary, the present invention has the following advantages:

[0031] The present invention adopts a circulating bacterial production mechanism to overcome the problem of enlarged particle size caused by insufficient bacterial production, and adopts a new type of evaporation, equipped with buffer preheating to ensure the evaporation effect. At the same time, multiple filtering processes are performed before the finished product, and the product safety is high.

[0032] The setting of the distributor allows the material to be evenly fed into the entire cylinder wall in an overflow manner, and the material is discharged continuously and evenly, which is convenient for subsequent scraper thinning and ensures that the separation effect of the evaporator is stable and efficient.

[0033] At the same time, the connection of the distributor is convenient and fast, with high stability and good sealing performance, which can ensure that the vacuum state in the evaporator is not affected.

[0034] The scraper cage structure adopts a segmented scraper structure, which moves up and down and swings centrifugally, allowing each scraper section to self-adjust the distance from the cylinder wall according to the thickness of the material. Under the action of centrifugal force, it is pressed against the cylinder wall more thinly to increase the evaporation efficiency.

[0035] What's more, the defoamer breaks up the foam to avoid the slow descent of materials due to the accumulation of foam, and avoids the waste of raw materials. BRIEF DESCRIPTION OF THE DRAWINGS

[0036] Figure 1 It is a schematic diagram of the structure of a scraped film evaporator;

[0037] Figure 2 It is a schematic diagram of the structure of the distributor;

[0038] Figure 3 It is a schematic diagram of the feeding structure;

[0039] Figure 4 It is a schematic diagram of the scraper cage structure;

[0040] Figure 5 This is an enlarged view of part A;

[0041] Figure 6 It is a schematic diagram of the structure of the present invention. DETAILED DESCRIPTION

[0042] The present invention will be further described below in conjunction with the accompanying drawings and embodiments: Example 1

[0043] An emulsified bacteria evaporation system, such as Figure 1-6 As shown, it includes an emulsification section, a bacterial preparation section, an evaporation section, a quantitative transfer filtration section and a storage section connected by pipelines.

[0044] The emulsification section includes an aqueous phase tank 100 and an organic solvent tank 200, which are mixed in proportion to an emulsification tank 300. In combination with a specific case, in this embodiment, the aqueous phase and the organic phase can be mixed in a ratio of 10:1.

[0045] The bacterial production section is a circulating bacterial production section, including a first bacterial production tank 400 and a second bacterial production tank 500 connected in parallel, and also includes a bacterial production machine 600. The bacterial production machine 600 is a high-pressure micro-jet bacterial production machine. During the bacterial production process, the discharge from the emulsification tank enters the first bacterial production tank, and then the bacterial production machine enters the second bacterial production tank and the first bacterial production tank in reverse. After repeated circulation until sufficient, the discharge enters the buffer tank 700 between the bacterial production section and the evaporation section, and then enters the evaporation section through the coil preheating structure 800.

[0046] The evaporation section includes at least two scraped film evaporators 900 , two in this embodiment, and the scraped film evaporators 900 are connected in series and / or in parallel under the action of pipelines and valves.

[0047] After the evaporation in the front evaporator is completed, it can enter the rear evaporator or directly enter the subsequent process. The choice of series and parallel connection is selected according to the special effect of the prepared product and the evaporation amount.

[0048] After evaporation is completed, it enters the quantitative transfer filtration section.

[0049] The quantitative transfer filtration section includes a quantitative tank 1000, and the rear end of the quantitative tank 1000 is connected to a first transfer tank 1200 through a first filter 1100 connected in parallel, which is a coarse filtration section.

[0050] A second filter 1400 is provided in series between the first transfer tank 1200 and the second transfer tank 1300, which is a fine filtration section.

[0051] A sterile filter 1600 is provided between the second transfer tank 1300 and the storage tank 1500 of the storage section, which serves as a sterile filtration section.

[0052] In the setting of the evaporator, the scraper film evaporator includes an evaporator cylinder 1 and a driving structure 2 arranged on the upper side of the evaporator cylinder 1. The scraper cage structure 3 is arranged in the evaporator cylinder 1, and its upper side is connected to the driving structure 2, and its lower side is limited by the bearing 12 on the lower head 11 at the bottom of the evaporator cylinder 1. A discharge port 13 is provided on the lower side of the lower head 11.

[0053] In terms of heat exchange mechanism, a water cavity 4 is provided on the side wall of the evaporator cylinder 1, and a water inlet 41 and a water outlet 42 are provided at the bottom and the top of the water cavity 4, that is, the heat exchange liquid enters at the bottom and exits at the top.

[0054] A heat-insulating layer 5 is provided outside the water cavity 4 to ensure a better heat exchange effect.

[0055] The evaporator cylinder 1 is provided with a cleaning port 14 and a vacuum interface 15 in sequence upward on the cylinder wall on the upper side of the scraper cage structure 3. The cleaning port 14 is used for cleaning the inside of the evaporator cylinder, and the vacuum interface is used for vacuuming during the evaporation process.

[0056] In terms of the feeding arrangement, a feeding structure 6 is provided on the wall of the evaporator cylinder 1 adjacent to the scraper cage structure 3 .

[0057] The feed structure includes a distributor 6-3 which is arranged between the upper cylinder 6-1 and the lower cylinder 6-2 of the evaporator cylinder 1 and is sealed.

[0058] Specifically, the first connecting flange 6-11 at the bottom of the upper cylinder 6-1 and the second connecting flange 6-21 at the top of the lower cylinder 6-2 are used to fix the upper and lower limit positions of the distributor 6-3, and connecting holes 6-38 are equally divided on the edge of the distributor 6-3. The connecting bolts 6-5 pass through the connecting holes 6-38 to fix the distributor 6-3 to the first connecting flange 6-11 and the second connecting flange 6-21.

[0059] Continue to refer to the attached Figure 2 The circumferential side wall of the distributor 6-3 is evenly divided with at least three feed ports 6-31, and in the present embodiment, the number of the feed ports is 4. The upper side surface of the distributor 6-3 is provided with a first connecting stop 6-32, a feed trough 6-33 and an overflow weir 6-34 from the outside to the inside, the lower side surface is provided with a second connecting stop 6-35, and the middle part is a through discharge port 13. The first connecting stop 6-32 and the second connecting stop 6-35 are provided with sealing rings 6-4 for sealing, that is, when the upper and lower connecting flanges are fixed to the distributor, the upper cylinder, the lower cylinder and the distributor can be sealed. Connection.

[0060] In the discharge setting, in order to ensure that the discharge can directly act on the cylinder wall, the edge of the discharge port 13 is flush with the inner walls of the upper cylinder 6-1 and the lower cylinder 6-2, that is, the outer end of the overflow weir arranged in a circular ring is flush with the inner wall of the cylinder.

[0061] The feed inlet 6-31 is connected to the feed internal outlet 6-37 arranged in the feed trough 6-33, so that the feed can enter the feed trough and then be discharged through the overflow weir.

[0062] It is worth noting that overflow notches are evenly distributed on the overflow weir, and the overflow notches are tooth-shaped overflow holes.

[0063] In terms of its working mechanism, the distributor is independent of the evaporator cylinder and is installed on the upper part of the evaporator cylinder. The material enters the internal feed trough through the feed port, then slowly flows out on the overflow weir, flows along the inner wall to the cylinder, and is thinned by the scraper inside the evaporator cylinder.

[0064] In terms of the setting of the driving structure, the driving structure 2 includes a motor 21 , a driving chamber 22 , a coupling 23 and a single-end mechanical seal 24 .

[0065] The motor flange is fixed to the top of the driving chamber 22 and acts on the coupling 23 . The bottom of the driving chamber 22 is fixed to the upper flange of the evaporator cylinder 1 . The coupling 23 is fixed to the scraper cage structure 3 .

[0066] In the setting of the scraper cage, the scraper cage structure includes a central rotating shaft 3-1 and an upper chuck 3-11 and a lower chuck 3-12 fixed to the upper and lower sides of the central rotating shaft 3-1.

[0067] The upper chuck 3-11 and the lower chuck 3-12 are hollow disc structures, and at least three scraper fixing shafts 3-3 are arranged between the two. In this embodiment, four are arranged, and the upper chuck 3-11 and the lower chuck 3-12 are evenly divided around the circumference.

[0068] The scraper fixing shaft 3-3 is overlapped with a plurality of hollow cylindrical scrapers 3-4, and there is an offset between the cylindrical scraper 3-4 and the scraper fixing shaft 3-3. At the same time, the distance between the topmost cylindrical scraper 3-4 and the upper chuck 3-11 is 2-5mm, so that the scraper can self-adjust during operation.

[0069] Furthermore, the edge of the cylindrical scraper 3-4 protrudes from the upper chuck 3-11 and the lower chuck 3-12.

[0070] The central rotating shaft 3 - 1 passes through the evaporator cylinder 1 and is fixed to the coupling 23 , and a single-end mechanical seal 24 acts at the flange connection.

[0071] An angular contact bearing 221 is also provided in the driving cavity 22 to act on the central rotating shaft 3-1 at the lower side of the coupling 23. This arrangement can self-regulate the central rotating shaft during the working process, play an anti-deviation role and bear greater force.

[0072] At the same time, the central shaft is also provided with a defoamer 3-5 on the upper side of the upper chuck 3-11.

[0073] Specifically, the defoamer 3-5 is a symmetrical paddle structure, and the paddles are evenly distributed with conical through holes 3-51.

[0074] The central shaft rotates under the action of the motor, that is, the motor drives the coupling, thereby driving the central shaft to rotate. Specifically, the central shaft is limited by the bearing on the lower head at the lower side, so the cylindrical scraper can move up and down and perform centrifugal swinging. The material enters the evaporator cylinder in an overflow manner from the feed structure and is diluted. At the same time, under the action of the water chamber, heat exchange and evaporation are performed.

[0075] Specifically, the material enters the cylinder of the evaporator from between the scraper on the lower side of the defoamer and the cylinder wall. When the evaporator is working, the cylinder is in a vacuum state due to the action of the vacuum pump. Some raw materials, after the front-end process and then entering the vacuum environment for heating, the solvents are prone to surface tension expansion, similar to blowing soap bubbles, producing foam.

[0076] The foam will carry part of the raw materials to escape from the vacuum pipe, causing waste. At the same time, the foam will accumulate in the cylinder, causing the material to descend slowly. At this time, under the action of the defoamer, the foam will be scraped into the conical hole from the large hole side of the conical hole, and then squeezed out from the small hole at the bottom of the cone. The foam will be broken up in the cycle here and will fall down. In the process, the solvent will evaporate due to heat and come out with the vacuum, and the liquid raw material will fall down.

[0077] In this solution, the diameter, length and weight of the cylindrical scraper are determined according to the specifications, evaporation area and cylinder diameter of the evaporator. The smaller the evaporator, the smaller the scraper size. The weight and length of the scraper are generally determined by the material. The more viscous the material, the longer the scraper and the heavier the weight.

[0078] The weight of the scraper is changed by changing the wall thickness and length. In order not to affect the efficiency of the scraper, the rotation diameter of the scraper shaft must also be changed if the wall thickness and length are changed.

[0079] Generally speaking, a heavier and longer scraper will produce better results.

[0080] Moreover, the advantage of the segmented scraper is that the distance from each segment of the scraper to the inside of the cylinder can be self-adjusted.

[0081] For example, the material on a certain section of the inner wall of the cylinder is a little thicker due to residence time and viscosity. Then when the scraper of this section is working, the natural distance between it and the cylinder wall is larger.

[0082] Similarly, if the material in other parts of the cylinder wall is very thin, the scraper will naturally be pressed against the cylinder wall due to the centrifugal force, and the spacing will be reduced by itself. In this way, each scraper can adjust the distance between itself and the cylinder wall according to the thickness of the material, and press the centrifugal force generated by the rotation of the central axis of the material as thin as possible onto the cylinder wall, thereby increasing the evaporation efficiency.

[0083] In summary, this solution adopts a circulating bacterial production mechanism to overcome the problem of enlarged particle size caused by insufficient bacterial production. It also adopts a new type of evaporation, combined with buffer preheating to ensure the evaporation effect. At the same time, multiple filtration processes are performed before the finished product, and the product is highly safe.

[0084] The evaporator uses a distributor to feed the material evenly to the entire cylinder wall in an overflow manner, and the material is discharged continuously and evenly, which is convenient for subsequent scraper thinning and ensures that the separation effect of the evaporator is stable and efficient.

[0085] At the same time, the connection of the distributor is convenient and fast, with high stability and good sealing performance, which can ensure that the vacuum state in the evaporator is not affected.

[0086] The scraper cage structure adopts a segmented scraper structure, which moves up and down and swings centrifugally, allowing each scraper section to self-adjust the distance from the cylinder wall according to the thickness of the material. Under the action of centrifugal force, it is pressed against the cylinder wall more thinly to increase the evaporation efficiency.

[0087] What's more, the defoamer breaks up the foam to avoid the slow descent of materials due to the accumulation of foam, and avoids the waste of raw materials.

[0088] The above embodiments are only for illustrating the technical concept and features of the present invention, and their purpose is to enable people familiar with the technology to understand the content of the present invention and implement it accordingly, and they cannot be used to limit the protection scope of the present invention. Any equivalent transformation or modification made according to the spirit of the present invention should be included in the protection scope of the present invention.

[0089] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "connected" and "connected" should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, and it can be the internal connection of two elements.

[0090] For those skilled in the art, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0091] It should be understood that the above-mentioned embodiments are merely illustrative and not restrictive. Without departing from the basic principles of the present invention, various obvious or equivalent modifications or substitutions that can be made by those skilled in the art to the above-mentioned details will be included in the scope of the claims of the present invention.

Claims

1. An emulsified bacteria evaporation system, characterized in that: It includes an emulsification section, a bacterial preparation section, an evaporation section, a quantitative transfer filtration section and a storage section connected by pipelines; The emulsification section comprises a water phase tank (100) and an organic solvent tank (200), which are mixed in proportion to an emulsification tank (300); The bacterial production section is a circulating bacterial production section, comprising a first bacterial production tank (400) and a second bacterial production tank (500) connected in parallel, and also comprising a bacterial production machine (600); A buffer tank (700) and a coil preheating structure (800) are sequentially arranged between the bacterial production section and the evaporation section; The evaporation section comprises at least two scraped film evaporators (900), and the scraped film evaporators (900) are connected in series and / or in parallel under the action of pipelines and valves; The quantitative transfer filtration section comprises a quantitative tank (1000), the rear end of the quantitative tank (1000) is connected to a first transfer tank (1200) via a first filter (1100) connected in parallel, a second filter (1400) is provided in series between the first transfer tank (1200) and the second transfer tank (1300), and a sterile filter (1600) is provided between the second transfer tank (1300) and the storage tank (1500) of the storage section; The scraper film evaporator (900) comprises an evaporator barrel (1) and a drive structure (2) arranged on the upper side of the evaporator barrel (1); a scraper cage structure (3) is arranged in the evaporator barrel (1), the upper side of which is connected to the drive structure (2), and the lower side is limited by a bearing (12) on a lower head (11) at the bottom of the evaporator barrel (1); a discharge port (13) is provided on the lower side of the lower head (11); a water cavity (4) is provided on the side wall of the evaporator barrel (1), and a water inlet (41) and a water outlet (42) are provided at the bottom and the top of the water cavity (4); a heat-insulating layer (5) is provided on the outer side of the water cavity (4); a cleaning port (14) and a vacuum interface (15) are provided on the barrel wall of the evaporator barrel (1) on the upper side of the scraper cage structure (3); and a feed structure (6) is provided on the barrel wall of the evaporator barrel (1) adjacent to the scraper cage structure (3); The driving structure (2) comprises a motor (21), a driving chamber (22), a coupling (23) and a single-end mechanical seal (24); the motor flange is fixed to the top of the driving chamber (22) and acts on the coupling (23); the bottom of the driving chamber (22) is fixed to the upper flange of the evaporator cylinder (1); and the coupling (23) is fixed to the scraper cage structure (3); The scraper cage structure (3) comprises a central rotating shaft (3-1) and an upper chuck (3-11) and a lower chuck (3-12) fixed to the upper and lower sides of the central rotating shaft (3-1); at least three scraper fixing shafts (3-3) are provided between the upper chuck (3-11) and the lower chuck (3-12); the scraper fixing shaft (3-3) is provided with a plurality of hollow cylindrical scrapers (3-4) in a stacked manner, and there is an offset between the cylindrical scrapers (3-4) and the scraper fixing shaft (3-3); the edge of the cylindrical scraper (3-4) protrudes from the upper chuck (3-11) and the lower chuck (3-12); the central rotating shaft (3-1) passes through the evaporator cylinder (1) and is fixed to the coupling (23); and the single-end mechanical seal (24) acts at the flange connection; The distance between the topmost cylindrical scraper (3-4) and the upper chuck (3-11) is 2-5 mm, and the scraper fixing shafts (3-3) are arranged in four numbers, and evenly divide the upper chuck (3-11) and the lower chuck (3-12) at the periphery; The feed structure (6) comprises a distributor (6-3) which is arranged between an upper cylinder (6-1) and a lower cylinder (6-2) of the evaporator cylinder (1) and is sealed and fixed; a first connecting flange (6-11) at the bottom of the upper cylinder (6-1) and a second connecting flange (6-21) at the top of the lower cylinder (6-2) are used for upper and lower limit fixation of the distributor (6-3); and at least three feed ports (6-31) are evenly distributed on the circumferential side wall of the distributor (6-3). The upper side of the distributor (6-3) is provided with a first connecting stop (6-32), a feed trough (6-33) and an overflow weir (6-34) from the outside to the inside, and the lower side is provided with a second connecting stop (6-35). The middle part is a through discharge port (13), the edge of the discharge port (13) is flush with the inner walls of the upper cylinder (6-1) and the lower cylinder (6-2), and the feed port (6-31) is connected to a feed inner outlet (6-37) arranged in the feed trough (6-33).

2. The emulsified bacteria evaporation system according to claim 1, characterized in that: The central rotating shaft (3-1) is also provided with a defoamer (3-5) on the upper side of the upper chuck (3-11); the defoamer (3-5) is a symmetrical paddle structure, and the paddles are evenly distributed with conical through holes (3-51).

3. The emulsified bacteria evaporation system according to claim 1, characterized in that: The first connection stop (6-32) and the second connection stop (6-35) are provided with sealing rings (6-4) for sealing, and the overflow weir (6-34) is evenly distributed with overflow notches.

4. The emulsified bacteria evaporation system according to claim 1, characterized in that: The number of the feed ports is 4, and the edge of the distributor (6-3) is equally divided with connection holes (6-38), and the connection bolts (6-5) pass through the connection holes (6-38) to fix the distributor (6-3) to the first connection flange (6-11) and the second connection flange (6-21).

5. The emulsified bacteria evaporation system according to claim 1, characterized in that: An angular contact bearing (221) is also provided in the driving cavity (22) and acts on the central rotating shaft (3-1) at the lower side of the coupling (23).

6. The emulsified bacteria evaporation system according to claim 1, characterized in that: The bacterial preparation machine (600) is a high-pressure microfluidic bacterial preparation machine.

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