A manufacturing device for producing heparin sodium

Abstract

The present invention discloses a production device for sodium heparin production, which relates to the field of sodium heparin production, including a reaction tank and an adsorption tank, wherein the reaction tank is located above the adsorption tank, an L-shaped plate is fixedly installed on the top side of the reaction tank, a motor is fixedly installed on the top side of the L-shaped plate, and a rotating shaft is fixedly installed on the output shaft of the motor. In the present invention, the motor is started to drive the rotating shaft to rotate, and the rotation of the rotating shaft can drive multiple stirring blades to rotate and stir, and the rotation of the rotating shaft drives the elliptical block to rotate, thereby driving the top rod to move, and the movement of the top rod will drive the annular disk to move upward, and the upward movement of the annular disk will drive the rotating rod to move upward, and the upward movement of the rotating rod can drive multiple stirring blades to move up and down, so that the multiple stirring blades can move up and down while rotating, so that the raw materials in the reaction tank can be fully stirred and reacted, thereby effectively improving the production output of sodium heparin.

Description

Technical Field

[0001] The invention relates to the technical field of heparin sodium production, and in particular to a manufacturing device for heparin sodium production. Background Art

[0002] Heparin Sodium (Heparin Sodium) Heparin Sodium is a mucopolysaccharide sulfate anticoagulant. Heparin Sodium is the sodium salt of aminoglucan sulfate extracted from the intestinal mucosa of pigs or cattle. It belongs to the mucopolysaccharide substance and exists in the form of heparin sodium-protein complex in the animal body. Medically, heparin sodium has anticoagulant effects both in vivo and in vitro, and can prolong coagulation time, prothrombin time and thrombin time. It is often used as an in vitro anticoagulant to prevent blood coagulation during blood transfusion and to store fresh blood in blood banks.

[0003] After searching, the patent with publication number CN206219482U discloses a production device of sodium heparin, which includes a reaction tank, an adsorption tank, an ion exchange column, a reagent preparation tank and a precipitation tank. The reaction tank, the adsorption tank, the ion exchange column and the precipitation tank are arranged in order from top to bottom, and the reaction tank, the adsorption tank, the ion exchange column and the precipitation tank are connected by pipelines. In the reaction tank, traditional sodium heparin is stirred by a stirring device during the production process. Most of the stirring devices are fixed in a horizontal position in a certain direction for stirring. The material in the reaction tank cannot fully react, thereby reducing the production output of sodium heparin. Therefore, a production device for sodium heparin production is needed to meet people's needs. Summary of the invention

[0004] The object of the present invention is to provide a production device for heparin sodium production, so as to solve the problem that in the production process of conventional heparin sodium in a reaction tank, the stirring device is used for stirring, and the stirring device is mostly fixed in a horizontal position in a certain direction for stirring, and the material in the reaction tank cannot be fully reacted, thereby reducing the production output of heparin sodium.

[0005] To achieve the above-mentioned purpose, the present invention provides the following technical solutions: a production device for sodium heparin production, comprising a reaction tank and an adsorption tank, wherein the reaction tank is located above the adsorption tank, an L-shaped plate is fixedly installed on the top side of the reaction tank, a motor is fixedly installed on the top side of the L-shaped plate, a rotating shaft is fixedly installed on the output shaft of the motor, the bottom end of the rotating shaft passes through the L-shaped plate, a rotating rod is movably installed on the bottom end of the rotating shaft, the bottom end of the rotating rod extends into the reaction tank, a plurality of stirring blades are fixedly installed on the rotating rod, and two guide rods are fixedly installed on the top side of the reaction tank.

[0006] Preferably, the same annular disk is fixedly installed, and the annular disk is movably sleeved on the rotating rod.

[0007] Preferably, an annular groove is provided on the top side of the annular disk, connecting blocks are fixedly installed on both sides of the rotating rod, sliding columns are fixedly installed on the bottom sides of the two connecting blocks, and the bottom ends of the two sliding columns are slidably installed in the two annular grooves respectively.

[0008] Preferably, a rotating rod is rotatably mounted on one side of the guide rod, a push rod is rotatably mounted on one end of the rotating rod, one end of the push rod is rotatably mounted on the bottom side of the annular disk, an extrusion rod is rotatably mounted on the other end of the rotating rod, a convex movable block is rotatably mounted on one end of the extrusion rod, and the convex movable block is movably mounted on the bottom side of the L-shaped plate.

[0009] Preferably, a movable groove is opened on the bottom side of the L-shaped plate, and the convex movable block is slidably installed in the movable groove. One end of the spring is fixedly installed on one side of the convex movable block, and the other end of the spring is fixedly installed on one inner wall of the movable groove.

[0010] Preferably, a movable groove is provided at the bottom end of the rotating shaft, the top end of the rotating rod extends into the movable groove, limiting grooves are provided on the inner walls on both sides of the movable groove, limiting blocks are fixedly installed on both sides of the rotating rod, and the sides of the two limiting blocks that are away from each other are respectively slidably installed in the two limiting grooves.

[0011] Preferably, an elliptical block is fixedly mounted on one side of the rotating shaft, and the elliptical block is matched with the convex movable block.

[0012] The beneficial effects of the present invention are:

[0013] In the present invention, the starting motor drives the rotating shaft to rotate, the rotation of the rotating shaft drives the limit block to rotate, the rotation of the limit block drives the rotating rod to rotate, the rotation of the rotating rod drives multiple stirring blades to rotate and stir, the rotation of the rotating shaft drives the elliptical block to rotate, when the elliptical block rotates, it will contact and squeeze the convex movable block, so as to drive the rotating rod to rotate, the rotation of the rotating rod drives the push rod to move, and the movement of the push rod will drive the annular disk to move upward.

[0014] In the present invention, the upward movement of the annular disk will drive the sliding column to move upward, so that the rotating rod will move upward, and the rotating rod will move in the moving groove. The up and down movement of the rotating rod can drive the multiple stirring blades to move up and down, so that the multiple stirring blades can move up and down while rotating, so that the raw materials in the reaction tank can be fully stirred and reacted, thereby effectively improving the production output of sodium heparin. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Figure 1 The present invention provides a three-dimensional structural schematic diagram of a production device for producing sodium heparin.

[0016] Figure 2 The present invention is a schematic structural diagram of a cross-section of a manufacturing device for producing sodium heparin proposed by the present invention.

[0017] Figure 3 The present invention provides a schematic structural diagram of a partial cross-section of a manufacturing device for producing sodium heparin.

[0018] Figure 4 A manufacturing device for producing heparin sodium proposed by the present invention Figure 2 Schematic diagram of the structure of part A.

[0019] In the figure: 1. reaction tank; 2. adsorption tank; 3. L-shaped plate; 4. motor; 5. rotating shaft; 6. moving groove; 7. rotating rod; 8. limiting block; 9. limiting groove; 10. stirring blade; 11. guide rod; 12. annular disk; 13. guide block; 14. annular groove; 15. sliding column; 16. connecting block; 17. movable groove; 18. convex movable block; 19. extrusion rod; 20. rotating rod; 21. push rod; 22. elliptical block. DETAILED DESCRIPTION

[0020] The technical solutions in the embodiments of the present invention will be described clearly and completely below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all the embodiments.

[0021] Reference Figure 1-4 A production device for producing sodium heparin includes a reaction tank 1 and an adsorption tank 2. The reaction tank 1 is located above the adsorption tank 2. An L-shaped plate 3 is fixedly installed on the top side of the reaction tank 1. A motor 4 is fixedly installed on the top side of the L-shaped plate 3. A rotating shaft 5 is fixedly installed on the output shaft of the motor 4. The bottom end of the rotating shaft 5 passes through the L-shaped plate 3. A rotating rod 7 is movably installed on the bottom end of the rotating shaft 5. The bottom end of the rotating rod 7 extends into the reaction tank 1. A plurality of stirring blades 10 are fixedly installed on the rotating rod 7. Two guide rods 11 are fixedly installed on the top side of the reaction tank 1.

[0022] In the present invention, the same annular disk 12 is fixedly installed, and the annular disk 12 is movably sleeved on the rotating rod 7 to limit the movement of the annular disk 12.

[0023] In the present invention, an annular groove 14 is opened on the top side of the annular disk 12, connecting blocks 16 are fixedly installed on both sides of the rotating rod 7, and sliding columns 15 are fixedly installed on the bottom sides of the two connecting blocks 16. The bottom ends of the two sliding columns 15 are respectively slidably installed in the two annular grooves 14. The annular grooves 14 and sliding columns 15 are arranged to facilitate the rotation of the rotating rod 7.

[0024] In the present invention, a rotating rod 20 is rotatably mounted on one side of the guide rod 11, a top rod 21 is rotatably mounted on one end of the rotating rod 20, one end of the top rod 21 is rotatably mounted on the bottom side of the annular disk 12, an extrusion rod 19 is rotatably mounted on the other end of the rotating rod 20, a convex movable block 18 is rotatably mounted on one end of the extrusion rod 19, and the convex movable block 18 is movably mounted on the bottom side of the L-shaped plate 3.

[0025] In the present invention, a movable groove 17 is opened on the bottom side of the L-shaped plate 3, and a convex movable block 18 is slidably installed in the movable groove 17. One end of a spring is fixedly installed on one side of the convex movable block 18, and the other end of the spring is fixedly installed on the inner wall of one side of the movable groove 17. The convex movable block 18 is easy to move in the movable groove 17, and after moving, it can be reset under the action of the elastic force of the spring.

[0026] In the present invention, a movable groove 6 is provided at the bottom end of the rotating shaft 5, and the top end of the rotating rod 7 extends into the movable groove 6. Limiting grooves 9 are provided on the inner walls on both sides of the movable groove 6. Limiting blocks 8 are fixedly installed on both sides of the rotating rod 7. The two limiting blocks 8 are slidably installed in the two limiting grooves 9 on the sides away from each other. The setting of the limiting blocks 8 and limiting grooves 9 allows the rotating shaft 5 to rotate while driving the rotating rod 7 to rotate, and the rotating rod 7 can move up and down in the rotating shaft 5.

[0027] In the present invention, an elliptical block 22 is fixedly mounted on one side of the rotating shaft 5 , and the elliptical block 22 is matched with the convex movable block 18 . When the elliptical block 22 rotates, it will contact and squeeze the convex movable block 18 .

[0028] How this utility works:

[0029] In the present invention, when sodium heparin is produced, it needs to react through the reaction tank 1, the starting motor 4 drives the rotating shaft 5 to rotate, the rotating shaft 5 rotates to drive the limit block 8 to rotate, the limit block 8 rotates to drive the rotating rod 7 to rotate, the rotating rod 7 rotates to drive multiple stirring blades 10 to rotate and stir, the rotating shaft 5 rotates to drive the elliptical block 22 to rotate, when the elliptical block 22 rotates, it will contact and squeeze the convex movable block 18, after the convex movable block 18 is squeezed, it will move in the movable groove 17 and compress the spring, the movement of the convex movable block 18 drives the extrusion rod 19 to move, the movement of the extrusion rod 19 drives the rotating rod 20 to rotate, the rotation of the rotating rod 20 drives the top rod 21 to move, the movement of the top rod 21 will drive the annular disk 12 to move upward, and the annular disk 12 moves upward to drive the guide block 13 slides on the guide rod 11, and the annular disk 12 moves upward, which will drive the sliding column 15 to move upward. The sliding column 15 moves upward and drives the connecting block 16 to move upward. The connecting block 16 moves upward and can drive the rotating rod 7 to move upward. The rotating rod 7 will move in the moving groove 6 and drive the limit block 8 to slide in the limit groove 9. The limit block 8 and the limit groove 9 are set, so that the rotating shaft 5 can drive the rotating rod 7 to rotate while the rotating shaft 5 rotates, and the rotating rod 7 can move up and down in the rotating shaft 5. The up and down movement of the rotating rod 7 can drive the multiple stirring blades 10 to move up and down, so that the multiple stirring blades 10 can move up and down while rotating, so that the raw materials in the reaction tank 1 can be fully stirred and reacted, thereby effectively improving the production output of heparin sodium, and it is convenient to use.

[0030] The above description is only a preferred specific implementation manner of the present invention, but the protection scope of the present invention is not limited thereto. Any technician familiar with the technical field can make equivalent replacements or changes according to the technical scheme and inventive concept of the present invention within the technical scope disclosed by the present invention, which should be covered by the protection scope of the present invention.

Claims

1. A production device for producing heparin sodium, comprising a reaction tank (1) and an adsorption tank (2), Features: The reaction tank (1) is located above the adsorption tank (2); an L-shaped plate (3) is fixedly mounted on the top side of the reaction tank (1); a motor (4) is fixedly mounted on the top side of the L-shaped plate (3); a rotating shaft (5) is fixedly mounted on the output shaft of the motor (4); the bottom end of the rotating shaft (5) passes through the L-shaped plate (3); a rotating rod (7) is movably mounted on the bottom end of the rotating shaft (5); the bottom end of the rotating rod (7) extends into the reaction tank (1); a plurality of stirring blades (10) are fixedly mounted on the rotating rod (7); and two guide rods (11) are fixedly mounted on the top side of the reaction tank (1); A guide block (13) is movably sleeved on each of the two guide rods (11), a same annular disk (12) is fixedly mounted between the two guide blocks (13), and the annular disk (12) is movably sleeved on the rotating rod (7); A rotating rod (20) is rotatably mounted on one side of the guide rod (11), a push rod (21) is rotatably mounted on one end of the rotating rod (20), one end of the push rod (21) is rotatably mounted on the bottom side of the annular disk (12), an extrusion rod (19) is rotatably mounted on the other end of the rotating rod (20), a convex movable block (18) is rotatably mounted on one end of the extrusion rod (19), and the convex movable block (18) is movably mounted on the bottom side of the L-shaped plate (3); An annular groove (14) is formed on the top side of the annular disk (12), connecting blocks (16) are fixedly mounted on both sides of the rotating rod (7), sliding columns (15) are fixedly mounted on the bottom sides of the two connecting blocks (16), and the bottom ends of the two sliding columns (15) are respectively slidably mounted in the two annular grooves (14); The bottom side of the L-shaped plate (3) is provided with a movable groove (17), a convex movable block (18) is slidably mounted in the movable groove (17), one end of a spring is fixedly mounted on one side of the convex movable block (18), and the other end of the spring is fixedly mounted on an inner wall of one side of the movable groove (17); A movable groove (6) is provided at the bottom end of the rotating shaft (5), the top end of the rotating rod (7) extends into the movable groove (6), limiting grooves (9) are provided on the inner walls on both sides of the movable groove (6), limiting blocks (8) are fixedly installed on both sides of the rotating rod (7), and the two limiting blocks (8) are slidably installed in the two limiting grooves (9) at the sides away from each other; An elliptical block (22) is fixedly mounted on one side of the rotating shaft (5), and the elliptical block (22) is matched with the convex movable block (18).

Images