Particle beam therapy device

Abstract

The present disclosure relates to the technical field of tumor radiotherapy, and specifically provides a particle beam therapy device. The particle beam therapy device includes a fixed support device, a synchrotron, a rotating support device, a first deflection magnet group, a second deflection magnet group, and an irradiation head. The fixed support device includes a base and a driving rotation mechanism; the rotating support device supports the synchrotron, and a first delivery channel is connected to the synchrotron. The driving rotation mechanism drives the rotating support device to rotate; the first deflection magnet group is arranged on the rotating support device, and the particle beam output through the first delivery channel enters the first deflection magnet group along the tangent direction of the input end of the first deflection magnet group; the particle beam output through the first deflection magnet group enters the second deflection magnet group along the tangent direction of the input end of the second deflection magnet group, and the output end of the second deflection magnet group points to the rotation center line of the rotating support device; the irradiation head is connected to the end of the second deflection magnet group.

Description

Technical Field

[0001] The present disclosure relates to the technical field of tumor radiotherapy, and particularly to a particle beam therapy device. Background Art

[0002] Particle accelerators can be applied to tumor radiotherapy, such as accelerating particle beams in heavy ion therapy or proton therapy. The accelerated particle beam needs to be guided to the target tissue of the patient, and it is often necessary to irradiate the target tissue from different directions to enhance the treatment effect or reduce the radiation dose to the surrounding healthy tissue.

[0003] In some tumor radiotherapy systems, the particle beam generating device and the accelerator are fixed to the ground, and the treatment room is arranged near the accelerator. Therefore, it is necessary to deflect and guide the particle beam emitted from the accelerator into the treatment room. Specifically, a complex system composed of deflection magnets and focusing magnets is required to guide the particle beam from the particle accelerator to the target, which is large in volume and expensive to manufacture. In addition, the distance between the treatment room and the accelerator is large, and the particle beam will have energy loss during transmission, which may lead to a reduction in the control accuracy of the irradiation dose. Summary of the Invention

[0004] In order to solve the above technical problems or at least partially solve the above technical problems, the present disclosure provides a particle beam therapy device.

[0005] The present disclosure provides a particle beam therapy device for emitting a particle beam to a target tissue, including:

[0006] A fixed support device including a base, on which a driving rotation mechanism is provided for serving as a support foundation;

[0007] A synchrotron for accelerating the particle beam, in which there is a deflection magnet, and a first conveying channel is connected to the synchrotron, and the first conveying channel conveys the particle beam obliquely upward;

[0008] A rotating support device for supporting the synchrotron, the rotating support device is rotatably arranged on the fixed support device; when the rotating support device makes a rotational movement, it has a rotation center line, and the power provided by the driving rotation mechanism can make the rotating support device rotate around the rotation center line;

[0009] A first deflection magnet group arranged on the rotating support device for receiving and conveying the particle beam output from the first conveying channel, the first deflection magnet group is arc-shaped, and the particle beam output from the first conveying channel enters the first deflection magnet group along the tangent direction of the input end of the first deflection magnet group;

[0010] The second deflection magnet group, connected to the first deflection magnet group, is configured to receive and transmit the particle beam output by the first deflection magnet group. The second deflection magnet group is arc-shaped, and the particle beam output by the first deflection magnet group enters the second deflection magnet group along the tangent direction of the input end of the second deflection magnet group. The output end of the second deflection magnet group points to the rotation center line of the rotary support device;

[0011] The irradiation head is connected to the end of the second deflection magnet group, and the particle beam is emitted from the irradiation head to the target tissue.

[0012] Optionally, the output end of the first deflection magnet group is connected to the input end of the second deflection magnet group through a second conveying channel, and the second conveying channel is tangent to the connection between the first deflection magnet group and the second deflection magnet group.

[0013] Optionally, a first focusing magnet is provided on the outer periphery of the second conveying channel.

[0014] Optionally, an included angle is formed between the plane where the first deflection magnet group is located and the plane where the second deflection magnet group is located.

[0015] Optionally, the input end of the first deflection magnet group is connected to the first conveying channel, and the first conveying channel is tangent to the connection between the first deflection magnet group and the first conveying channel.

[0016] Optionally, a second focusing magnet is provided on the outer periphery of the first conveying channel.

[0017] Optionally, the plane where the first deflection magnet group is located and the plane where the second deflection magnet group is located are coplanar.

[0018] Optionally, at least some of the structures or parameters of the first deflection magnet group and the second deflection magnet group are the same as those of the deflection magnet group in the synchrotron.

[0019] Optionally, the structure and parameters of the deflection magnet body in the second deflection magnet group are the same as those of the deflection magnet body in the deflection magnet group in the synchrotron, and the number of the deflection magnet bodies in the second deflection magnet group is the same as the number of the deflection magnet bodies in the deflection magnet group in the synchrotron.

[0020] Optionally, the output end of the first deflection magnet group is inclined obliquely upward, such that the included angle between the plane where the first deflection magnet group is located and the horizontal plane is β, and the rotation angle of the second deflection magnet group is 90° + β.

[0021] Optionally, the included angle β between the plane where the first deflection magnet group is located and the horizontal plane is less than or equal to 30°.

[0022] Optionally, the radius of curvature of the deflection part formed by the deflection magnets in the first deflection magnet group and the second deflection magnet group is the same as that of the deflection part formed by the deflection magnets in the synchrotron.

[0023] Optionally, the particle beam output from the second deflection magnet group is perpendicular to the rotation center line of the rotation support device.

[0024] Optionally, the rotation center line of the rotation support device is arranged in the horizontal direction or parallel to the support surface of the base.

[0025] Optionally, the direction of the particle beam output from the first deflection magnet group is parallel to the horizontal plane or the support surface of the base.

[0026] Optionally, annular structures are provided on both sides of the rotation support device. The annular structures are coaxial with the rotation support device. The annular structures are rotatably arranged on the fixed support device, and the outer diameter of the annular structures is smaller than the radial distance at the outermost radial position of the rotation support device.

[0027] Optionally, the deflection magnet bodies in the first deflection magnet group, the deflection magnet bodies in the second deflection magnet group, and the deflection magnet bodies in the deflection magnet group in the synchrotron all have focusing edges.

[0028] Optionally, the vertical plane between the plane where the particle beam movement trajectory is located in the first transport channel and the plane where the particle beam movement trajectory is located in the synchrotron is perpendicular to the horizontal plane or the support surface of the base.

[0029] Optionally, the plane where the particle beam movement trajectory is located in the synchrotron is perpendicular to the support surface of the base or the horizontal plane.

[0030] The technical solutions provided by the embodiments of the present disclosure have the following advantages compared with the prior art:

[0031] Compared with the structure in which the synchrotron and the beam transport device are arranged separately, the synchrotron, the first deflection magnet group, and the second deflection magnet group integrated on the rotation support device can significantly save space. Moreover, the particle beam output from the synchrotron enters the first deflection magnet group along the tangent direction of the input end of the first deflection magnet group. Therefore, there is no need to arrange deflection magnets and focusing magnets at the input end of the first deflection magnet group, thereby reducing the overall height of the particle beam therapy device. The reduction in height can reduce the space occupied by the particle beam therapy device, and further save the construction cost and construction difficulty of the building accommodating the entire particle beam therapy device, realizing a super-small synchrotron particle beam therapy device. Description of the Drawings

[0032] The accompanying drawings herein are incorporated into and constitute a part of this specification, showing embodiments consistent with the present disclosure and, together with the specification, are used to explain the principles of the present disclosure.

[0033] To more clearly illustrate the technical solutions in the embodiments of the present disclosure or the prior art, the following will briefly introduce the accompanying drawings required for use in the description of the embodiments or the prior art. Obviously, for those of ordinary skill in the art, other accompanying drawings can be obtained based on these drawings without creative efforts.

[0034] Figure 1 Structural schematic diagram of the particle beam therapy device according to the embodiment of the present disclosure;

[0035] Figure 2 For Figure 1 Top view;

[0036] Figure 3 For Figure 1 Rear view;

[0037] Figure 4 Schematic diagram of the particle beam therapy device after hiding the rotation support device;

[0038] Figure 5 Schematic diagram of the particle beam therapy device according to the embodiment of the present disclosure provided with a cylinder;

[0039] Figure 6 For Figure 5 Top view;

[0040] Figure 7 Schematic diagram of a third focusing magnet provided between the first deflection magnet group and the second deflection magnet group;

[0041] Figure 8 Structural schematic diagram of the particle beam therapy device according to the embodiment of the present disclosure having a second delivery channel;

[0042] Figure 9 For Figure 8 Front view;

[0043] Figure 10 For Figure 8 Left view;

[0044] Figure 11 For Figure 8 Top view;

[0045] Figure 12 Schematic diagram of the particle beam therapy device according to the embodiment of the present disclosure provided with a second delivery channel and a cylinder;

[0046] Figure 13Schematic diagram of a particle beam therapy device with a second delivery channel after hiding the rotation support device;

[0047] Figure 14 is Figure 13 front view of;

[0048] Figure 15 is Figure 13 left view of;

[0049] Figure 16 is Figure 13 top view of;

[0050] Figure 17 Schematic diagram of annular support plates arranged on both sides of the rotation support device described in the embodiment of the present disclosure;

[0051] Figure 18 Schematic diagram of the positional relationship between the synchrotron and the first delivery channel described in the embodiment of the present disclosure;

[0052] Figure 19 Schematic diagram of the plane where the first deflection magnet group is located described in the embodiment of the present disclosure;

[0053] Figure 20 Schematic diagram of the vertical plane between the plane of the particle beam movement trajectory and the plane of the particle beam movement trajectory of the synchrotron described in the embodiment of the present disclosure.

[0054] Wherein, 10, plane where the synchrotron is located; 11, plane where the first deflection magnet group is located; 12, plane where the second deflection magnet group is located; 13, vertical plane; 14, rotation center line; 100, fixed support device; 110, first support; 120, second support; 200, rotation support device; 210, annular plate; 220, cylinder; 230, support rod; 240, annular support plate; 300, injection device; 310, drive device; 400, synchrotron; 410, first deflection magnet body; 500, first deflection magnet group; 510, second deflection magnet body; 600, second deflection magnet group; 610, third deflection magnet body; 700, support device; 800, irradiation head; 900, second delivery channel; 901, first focusing magnet; 910, first delivery channel; 911, second focusing magnet; 920, third focusing magnet. Detailed implementation manners

[0055] In order to be able to more clearly understand the above-mentioned objects, features and advantages of the present disclosure, the solutions of the present disclosure will be further described below. It should be noted that, without conflict, the embodiments of the present disclosure and the features in the embodiments may be combined with each other.

[0056] In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present disclosure. However, the present disclosure may be practiced in other ways different from those described herein. Obviously, the embodiments in the specification are only a part of the embodiments of the present disclosure, rather than all of the embodiments.

[0057] Combined with Figures 1 to 3 As shown, the particle beam therapy device provided by the embodiment of the present application is used to emit a particle beam towards a target tissue. The particle beam therapy device includes a fixed support device 100, a rotating support device 200, an injection device 300, a synchrotron 400, a first deflection magnet group 500, a second deflection magnet group 600, a support device 700, a driving device 310, an irradiation head 800, and a control device (not shown in the figure).

[0058] The fixed support device 100 is fixed to the ground as an installation base. In some embodiments, the base of the fixed support device 100 is the ground. A driving rotation mechanism is provided on the base for serving as a support foundation. The injection device 300 includes a particle source, which is fixed on the rotating support device 200 and is used to generate a particle beam and preliminarily accelerate the particle beam and then inject it into the synchrotron 400. Specifically, it can be a proton beam, a carbon ion beam, a helium ion beam, etc.

[0059] Combined with Figure 2 and Figure 3 As shown, the synchrotron 400 is fixed on the rotating support device 200 and is used to receive and accelerate the particle beam generated by the injection device 300. There are deflection magnets in the synchrotron 400. Preferably, the synchrotron 400 is fixed on the rotating support device 200 in an upright state, that is, the plane 10 where the particle beam movement trajectory is located in the synchrotron 400 is perpendicular to the support surface or the horizontal plane of the base, reducing the internal space occupied by the rotating support device 200. In some other embodiments, the synchrotron 400 can also be inclined and arranged in the rotating support device 200, that is, the plane where the synchrotron 400 is located forms a certain angle with the vertical plane. This design method can reduce the height of the particle beam therapy device. Combined with Figure 11 and Figure 19 As shown, where, hereinafter, the plane 10 where the synchrotron is located, the plane 11 where the first deflection magnet group is located, and the plane 12 where the second deflection magnet group is located all refer to the plane where the particle beam movement trajectory is located in each device.

[0060] The particle beam passes through the first deflection magnet group 500 and the second deflection magnet group 600 to receive the accelerated particle beam in turn, and irradiates the target area through the irradiation head 800. The support device 700 is used to support the patient. The support device 700 is driven by a movable mechanical mechanism (not shown) to adjust its relative position with the irradiation head 800. The support device 700 is preferably a treatment bed, which can be moved by a mechanical arm or a roller movable seat provided at the bottom. The driving device 310 is used to drive the rotating support device 200 to rotate on the fixed support device 100. The synchrotron 400 is connected to a first conveying channel 910, and the first conveying channel 910 conveys the particle beam obliquely upward.

[0061] Combination Figure 4 , Figures 13 to 16 As shown, the synchrotron 400 includes four groups of deflection magnet groups and an accelerator. The number of deflection magnet bodies in each group of deflection magnet groups is multiple, and each group of deflection magnet groups includes four first deflection magnet bodies 410 in the illustrated embodiment. The accelerator may be a radio frequency accelerator. The first deflection magnet body 410 is used to deflect the particle beam through its magnetic field so that the particle beam can rotate along a circular orbit. The synchrotron 400 accelerates the particle beam to rotate in a circular manner to increase the energy or maintain it in a circular orbit. Further optimized, the first deflection magnet body 410 may also be configured to have an edge focusing effect. Among them, the number of the first deflection magnet bodies 410 in each group of deflection magnet groups shown in the figure is multiple, and the structure and parameters of the first deflection magnet bodies 410 in each group of deflection magnet groups are different. The figure is only for illustration and does not represent the actual structure of the first deflection magnet body 410. In some optional embodiments, the number of the first deflection magnet body 410 in each group of deflection magnet groups may also be one, so that the beam is rotated by 90 degrees. In other embodiments, the shape of the synchrotron 400 may also be a rounded rectangle or the like, and each rounded corner is composed of a plurality of deflection magnets, and the deflection magnets at the rounded corners can deflect the beam.

[0062] The fixed support device 100 includes a base and a driving rotation mechanism. Figure 1 , Figure 8 and Figure 9 As shown, as a preferred solution, the driving rotation mechanism can be a plurality of rollers and a driving device 310, the rollers are rotatably arranged on the base, the axes of the plurality of rollers are parallel, and the plurality of rollers are arranged on the base along a concave arc track, and the outer peripheral surface of the roller forms a concave arc track. The driving device 310 can drive at least one roller to rotate. As an embodiment, the driving device 310 can be a motor or a motor reducer, or a reduction motor or other mechanism that can provide the roller pivot rotation by electric power. The driving rotation mechanism can also be other mechanisms that can drive an object to rotate.

[0063] Combination Figure 1and Figure 3 As shown in Figure 3 , the rotating support device 200 is used to support the synchrotron 400, that is, the synchrotron 400 is installed on the rotating support device 200, and the synchrotron 400 is coaxially arranged with the rotating support device 200. The rotating support device 200 is rotatably arranged on the fixed support device 100. When the rotating support device 200 makes a rotational movement, it has a rotation center line 14. The power provided by the driving mechanism can make the rotating support device 200 rotate around the rotation center line 14. Preferably, the rotation center line 14 of the rotating support device 200 is arranged parallel to the horizontal plane or the support surface of the base (i.e., the upper surface of the base), which is convenient for installation and control. In some embodiments, the rotating support device 200 is an annular bracket, specifically including two annular plates 210. The two annular plates 210 are concentrically arranged and spaced apart, so that a space for installing the synchrotron 400 is formed between the two annular plates 210. The outer peripheral surface of the rotating support device 200 is equidiameter with the arc-shaped trajectory arranged by the outer edges of the rollers in the fixed support device 100, and is rotatably arranged on the outer peripheral surface of the rollers. The outer peripheral surface of the rollers is in tangential contact with the outer peripheral surface of the rotating support device 200. When the rollers rotate, they can drive the rotating support device 200 to rotate.

[0064] It should be understood that the shape of the rotating support device 200 and its connection method with the fixed support device 100 are not limited to the above structure, and other structures that can realize the installation and fixation of the synchrotron 400 and can rotate on the fixed support device 100 should also fall within the scope of protection required by the present disclosure. For example, the outer shape of the rotating support device 200 can be square, polygonal, etc., and the internal structure can adopt a hollow truss structure formed by fixing and connecting short metal round tubes and cylinders to each other, which can greatly reduce the weight of the rotating support device 200.

[0065] The rotatable connection between the rotating support device 200 and the fixed support device 100 can also be in other forms. For example, an annular structure can be provided on both end faces of the rotating support device 200 (the annular structure can be an arc-shaped or open ring that can make the synchrotron 400 rotate a set angle. The central angle of the arc or ring ensures that the synchrotron 400 can rotate a preset angle, such as greater than or equal to 90°. Preferably, it is a ring structure, as Figure 17 shown), and two fixed support devices 100 are provided correspondingly. The annular structure is coaxial with the rotation center of the rotating support device 200. The annular structure is rotatably arranged on the fixed support device 100, and the outer diameter of the annular structure is smaller than the radial distance at the farthest point in the radial direction of the rotating support device 200. At this time, the fixed support device 100 can make the radius of the annular structure smaller. The outer peripheral surfaces of the two annular structures cooperate with the rollers on the fixed support device 100, and the rotating support device 200 is driven to rotate by the meshing or friction between the rollers and the outer peripheral surfaces of the annular structures.

[0066] Specifically, as Figure 17 shown, a plurality of support rods 230 are provided on both sides of the rotary support device 200. The annular structure is an annular support plate 240. The annular support plate 240 is arranged at the end of the support rod 230. Thus, the two annular support plates 240 are fixedly supported on both sides of the rotary support device 200 through the support rods 230. The outer peripheral surface of the annular support plate 240 cooperates with the rollers on the fixed support device 100. The rotation of the rollers drives the annular support plate 240 to rotate. That is, rollers are provided on both sides of the rotary support device 200. The rollers are rotatably arranged on the base. The axes of the plurality of rollers are parallel. The plurality of rollers are arranged on the base along a sunken arc track. The outer peripheral surface of the roller forms a sunken arc track and is tangent to the outer edge of the annular support plate 240. The driving device 310 can drive at least one roller to rotate. By supporting the annular support plate 240 with the roller groups on both sides, it can ensure that the rotary support device 200 is more stably supported and rotates. Preferably, the rotary support device 200 is provided with a mechanism that can ensure that the rotary support device 200 does not roll over during rotation. This mechanism can be arranged inside the roller frame, or on the base, or on the top or both side walls of the building body accommodating the particle beam therapy device. For example, rollers or ball mechanisms are provided inside the roller frame. The rollers or balls abut against the surface of the rotary support device 200. Preferably, the support rod 230 is perpendicular to the plane where the rotary support device 200 is located. The center line of the annular support plate 240 coincides with the rotation center line 14 of the rotary support device 200, so that the rotation of the annular support plate 240 drives the rotary support device 200 to rotate along its center line. Further optimized, as long as the diameter of the annular support plate 240 is reduced as much as possible, it can ensure that the particle beam therapy device does not interfere during rotation. For example, first ensure that the part with the largest radial distance of the rotary support device does not interfere with the base during the rotation of the set angle. This design method can further reduce the overall height of the particle beam therapy device.

[0067] In some other embodiments, the way to drive the rotary support device to rotate can be through gear transmission. A driving device is provided on the base. The driving device is connected with a first gear. The driving device can drive the first gear to rotate. Correspondingly, a second gear meshing with the first gear is arranged on the outer periphery of the annular plate 210 or the annular support plate 240. Thus, the rotation of the first gear drives the annular plate 210 or the annular support plate 240 to rotate. It can be seen that the specific cooperation mode between the fixed support device 100 and the rotary support device 200 is not limited, as long as it satisfies that the fixed support device 100 drives the rotary support device 200 to rotate around its rotation center line 14.

[0068] Combined with Figures 1 to 3 、 Figures 8 to 10As shown, the first deflection magnet group 500 is disposed on the rotary support device 200 and is used to receive and transport the particle beam output by the synchrotron 400, that is, to receive and transport the particle beam output by the first transport channel 910. The first deflection magnet group 500 is arc-shaped, and the particle beam output through the first transport channel 910 enters the first deflection magnet group 500 along the tangent direction of the input end of the first deflection magnet group 500, that is, the tangent direction of the input end of the first deflection magnet group 500 coincides with the transport direction of the particle beam output by the synchrotron 400. Combining Figure 3 、 Figure 6 and Figure 8 shown, specifically, the first deflection magnet group 500 includes a plurality of deflection magnets. In the illustrated embodiment, the first deflection magnet group 500 includes three second deflection magnet bodies 510. The three second deflection magnet bodies 510 are used to deflect the particle beam through their magnetic fields, so that the particle beam is output from the first deflection magnet group 500 in a set direction. In other embodiments, the number of the second deflection magnet bodies 510 can also be four. And when the number of the second deflection magnet bodies 510 is four, the central angle of at least one second deflection magnet body 510 is smaller than the central angle of the deflection magnet body at the corresponding position in the deflection magnet group of the synchrotron 400, so that the particle beam output direction meets the requirements. Of course, the number of the second deflection magnet bodies 510 can also be other numbers. For example, the number of the second deflection magnet bodies 510 can also be one, and the central angle of the second deflection magnet body 510 at the corresponding position in the second deflection magnet group 500 can be the same as or different from the central angle of the first deflection magnet body 410 at the corresponding position in the deflection magnet group of the synchrotron 400, which is designed according to specific requirements. Wherein, the central angle is the central angle of the deflection magnet body or the deflection magnet group where the beam motion trajectory forms an arc on the plane where it is located.

[0069] It should be noted that the tangency mentioned above and below refers to the tangency with the trajectory formed by the motion direction of the particle beam.

[0070] Combining Figures 1 to 7As shown, the second deflection magnet group 600 is connected to the first deflection magnet group 500 and is used to receive and transmit the particle beam output by the first deflection magnet group 500. The second deflection magnet group 600 is arc-shaped, and the particle beam output by the first deflection magnet group 500 enters the second deflection magnet group 600 along the tangent direction of the input end of the second deflection magnet group 600. That is, the transport direction of the particle beam output by the first deflection magnet group 500 is parallel to the tangent direction of the input end of the second deflection magnet group 600. The output end of the second deflection magnet group 600 points to the rotation center line 14 of the rotation support device 200. In the implementation scheme where the input end of the second deflection magnet group 600 is horizontal and the output end is vertical, the second deflection magnet group 600 can directly adopt the same deflection magnet group as the synchrotron 400, that is, the structure, parameters, and the number of deflection magnet bodies are the same, which simplifies the control system.

[0071] The second deflection magnet group 600 includes a plurality of deflection magnet bodies, and the deflection magnet body in the second deflection magnet group 600 can also be one. In some preferred embodiments, as shown in the illustrated embodiment, the second deflection magnet group 600 includes four third deflection magnet bodies 610. The four third deflection magnet bodies 610 are used to deflect the particle beam through their magnetic fields so that the particle beam is output in the direction of the rotation center line 14 of the rotation support device 200. This design method makes the number of the third deflection magnet bodies 610 the same as the number of the first deflection magnet bodies 410 in each group of deflection magnet groups in the synchrotron 400. Therefore, only the structural design or the number of deflection magnets in the first deflection magnet group 500 needs to be changed. The second deflection magnet group 600 can directly adopt the deflection magnet group in the synchrotron 400, making the design and installation of the particle beam treatment device as a whole more convenient. The irradiation head 800 is connected to the end of the second deflection magnet group 600, and the particle beam is emitted from the irradiation head 800 to the target tissue. Further optimally, a focusing magnet can be provided between the irradiation head 800 and the second deflection magnet group 600.

[0072] In some other embodiments, the number of the first deflection magnet bodies 410 in each group of deflection magnet groups in the synchrotron 400 can be one. At this time, the number of the second deflection magnet bodies 510 and the number of the third deflection magnet bodies 610 should also be one. Specifically, one deflection magnet body realizes a 90° deflection. Among them, the synchrotron needs 4 first deflection magnet bodies 410 to complete one revolution of the beam. Or one deflection magnet body realizes a 60° deflection, and the synchrotron needs 6 first deflection magnet bodies 410 to complete one revolution of the beam. It can be seen that the deflection angle of the deflection magnet body is not limited, as long as the deflection requirement is met, and the number of deflection magnet bodies in the synchrotron should enable the beam to make one revolution. It should be noted that a separate focusing magnet needs to be provided before and after each deflection magnet body in this embodiment to avoid beam divergence; the deflection magnet body does not need to adopt a focusing edge.

[0073] Compared with the structure in which the synchrotron 400 and the beam transport device are arranged separately, the synchrotron 400, the first deflection magnet group 500 and the second deflection magnet group 600 integrated on the rotary support device 200 can significantly save space. And the particle beam output by the synchrotron 400 enters the first deflection magnet group 500 along the tangent direction of the input end of the first deflection magnet group 500. Therefore, there is no need to set a deflection magnet and a focusing magnet at the input end of the first deflection magnet group 500, thereby reducing the overall height of the particle beam therapy device. The reduction in height can reduce the space occupied by the particle beam therapy device, and further save the construction cost and construction difficulty of the building that houses the particle beam therapy device as a whole, realizing a super-small synchrotron particle beam therapy device. Among them, the building that houses the particle beam therapy device needs to have a shielding function. The thicker the wall and the higher the height used, the construction cost and construction difficulty will increase sharply.

[0074] Combined Figure 3 、 Figure 4 and Figure 7As shown, the first transport channel 910 extends obliquely upward from the middle of the synchrotron 400, thereby transporting the particle beam obliquely upward. The connection between the first deflection magnet group 500 and the second deflection magnet group 600 is above the rotation center line 14 of the rotation support device 200, and the output end of the second deflection magnet group 600 points to the rotation center line 14 of the rotation support device 200, facilitating the emission of the particle beam from top to bottom. Further optimized, the plane where the second deflection magnet group 600 is located is perpendicular to the horizontal plane, that is, the plane formed by the movement trajectory of the particle beam in the second deflection magnet group 600 is perpendicular to the horizontal plane, so that the particle beam output from the second deflection magnet group 600 is perpendicular and points to the rotation center line 14 of the rotation support device 200, enabling the particle beam to be substantially perpendicular to the support surface of the lying patient and the virtual central axis thereof. This central axis can be set to pass through the tumor position of the patient and pass through the rotation center line 14, preferably collinear with the rotation center line 14. After rotating the synchrotron 400, the beam can be rotated in a vertical plane perpendicular to the support surface and the virtual central axis of the patient's torso.

[0075] Further optimized, at least part of the structure or parameters of the first deflection magnet group 500 and the second deflection magnet group 600 are the same as those of the deflection magnet group in the synchrotron 400. Preferably, the structure and parameters of the deflection magnet body in the second deflection magnet group 600 are the same as those of the deflection magnet body in the deflection magnet group of the synchrotron 400, and the number of deflection magnet bodies in the second deflection magnet group 600 is the same as the number of deflection magnet bodies in the deflection magnet group of the synchrotron 400. Preferably, by adjusting the inclination angle of the plane 10 where the synchrotron is located or adjusting the inclination angle of the first delivery channel 910 relative to the plane 10 where the synchrotron is located, the plane 11 of the first deflection magnet group and the plane 12 of the second deflection magnet group can be made coplanar. Of course, the curvature radius of the first deflection magnet group 500 or the second deflection magnet group 600 can also be adjusted to achieve coplanarity, but the first deflection magnet group 500 or the second deflection magnet group 600 with the changed curvature radius cannot adopt the same control as the deflection magnet group in the synchrotron 400. At this time, no deflection magnets and focusing magnets need to be arranged between the coplanar first deflection magnet group 500 and the second deflection magnet group 600, simplifying the structure and at the same time reducing the axial length of the particle beam therapy device. This design method can use basically the same control parameters to control the deflection of the beam current, thereby reducing the difficulty and complexity of controlling the deflection of the irradiation treatment path of the patient after the beam current is extracted from the synchrotron 400, and can simplify the control system. Preferably, the synchrotron 400, the first deflection magnet group 500 and the second deflection magnet group 600 are all composed of multiple deflection magnet bodies with focusing edges. While realizing the deflection of the particle beam, they have a focusing function, and separate focusing magnets can be omitted, so that the overall volume and weight of the particle therapy device can be greatly reduced. When the vertically arranged particle beam therapy device rotates, the rotation drive is simpler and does not require a larger power rotation drive, and at the same time is beneficial to the precision control of the rotational movement. It should be noted that the first deflection magnet group 500 and the second deflection magnet group 600 can also use magnets without an edge focusing function and cooperate with separate focusing magnets for focusing. Further optimized, the structure and parameters of the deflection magnet body in the second deflection magnet group 600 are the same as those of the deflection magnet body in the synchrotron 400. Similarly, this design method enables the second deflection magnet group 600 to directly adopt the deflection magnet group in the synchrotron 400, and the number of deflection magnets in the second deflection magnet group 600 is the same as the number of deflection magnets in the synchrotron 400 that can deflect 90°, thus making the design and installation more convenient.

[0076] Wherein, the axial directions mentioned above and below refer to the length direction of the rotation center line 14 of the rotation support device 200.

[0077] Further optimized, the radius of curvature of the deflection part formed by the deflection magnets in the first deflection magnet group 500 and the second deflection magnet group 600 is the same as that of the deflection part formed by the deflection magnets in the synchrotron 400. It should be noted that the radius of curvature of the deflection part formed by the deflection magnet bodies in the first deflection magnet group 500 and the second deflection magnet group 600 may also be different from that of the deflection part formed by the deflection magnet bodies in the synchrotron 400, which is selected according to the number of deflection magnet bodies. Of course, if the number of deflection magnet bodies in the first deflection magnet group 500 and the second deflection magnet group 600 is the same as that of the deflection magnet bodies in the synchrotron 400, the radius of curvature of the deflection part formed by the deflection magnet bodies in the first deflection magnet group 500 and the second deflection magnet group 600 is preferably the same as that of the deflection part formed by the deflection magnet bodies in the synchrotron 400.

[0078] In some embodiments, as shown in Figures 1 to 4 shown, the first deflection magnet group 500 is directly connected to the second deflection magnet group 600. This design can shorten the axial length of the particle transport channel, thereby shortening the length of the treatment room, which is beneficial to the miniaturization of the overall particle beam therapy device. As Figure 7 shown, further optimized, in order to avoid the problem of divergence when the particle beam transitions between the first deflection magnet group 500 and the second deflection magnet group 600, a third focusing magnet 920 is provided between the first deflection magnet group 500 and the second deflection magnet group 600. The third focusing magnet 920 is preferably one to avoid increasing the axial length of the particle transport channel.

[0079] In other embodiments, as shown in Figures 8 to 16 shown, the output end of the first deflection magnet group 500 is connected to the input end of the second deflection magnet group 600 through a second transport channel 900, and the second transport channel 900 is tangent to the connection points of the first deflection magnet group 500 and the second deflection magnet group 600. By adjusting the central angle of the beam of the first deflection magnet group 500, the length of the second transport channel 900 can be reduced, thereby reducing the overall equipment cost. Among them, the length of the second transport channel 900 is designed according to specific requirements such that the output end of the second deflection magnet group 600 points to the rotation center line 14 of the rotation support device 200.

[0080] It should be noted that Figure 7 and Figure 8 the difference between the two embodiments is that the central angles of the particle beams of the first deflection magnet group 500 in the two embodiments are different. Among them, Figure 8 the central angle of the particle beam of the first deflection magnet group 500 in the Figure 7As shown, in order to make the direction of the particle beam output from the first deflection magnet set 500 parallel to the bottom surface or the horizontal plane, the angle between the first deflection magnet set 500 and the plane where the trajectory of the particle beam in the synchrotron 400 is located is reduced, so that its outlet deflects towards the rotation center line 14, thereby reducing the distance between the first deflection magnet set 500 and the second deflection magnet set 600, that is, shortening the length of the first transport channel 900. Thus, the axial length of the particle beam treatment device is reduced, and the volume of the building required to accommodate the treatment device is reduced, which is conducive to the miniaturization of the device.

[0081] Combined with Figure 11 and Figure 16 As shown, the plane 11 where the first deflection magnet set is located forms an angle with the plane 12 where the second deflection magnet set is located. Thus, the second deflection magnet set 600 can deflect the particle beam downward. At the same time, because there is a certain angle between the plane where the first deflection magnet set 500 is located and the plane where the second deflection magnet set 600 is located, in order to avoid the divergence of the particle beam, a plurality of focusing magnets are arranged between the first deflection magnet set 500 and the second deflection magnet set 600. Specifically, since the first deflection magnet set 500 and the second deflection magnet set 600 are connected through the second transport channel 900, therefore, a first focusing magnet 901 is arranged on the outer periphery of the second transport channel 900. Among them, the first focusing magnet 901 can be one, two or more, and it is designed according to the length of the second transport channel 900. And when the first focusing magnet 901 is multiple, the multiple first focusing magnets 901 are arranged at intervals along the length direction of the second transport channel 900. On the premise of ensuring that beam focusing can be achieved and when the radiation of the synchrotron 400, the injection device 300, etc. is not too large during treatment, in order to reduce the length of the second transport channel 900, the fewer the number of the first focusing magnets 901, the better.

[0082] Combined with Figure 4 , Figure 8 , Figure 9 , Figure 18 and Figure 20As shown, a first transport channel 910 is connected to the synchrotron 400. The vertical plane between the particle beam movement trajectory of the first transport channel 910 and the plane where the particle beam movement trajectory of the synchrotron 400 is located is tangent to the particle beam trajectory before being led out from the synchrotron 400. Moreover, the vertical plane 13 between the particle beam movement trajectory in the first transport channel 910 and the plane where the particle beam movement trajectory in the synchrotron 400 is located is perpendicular to the horizontal plane or the support surface of the base, so that the particle beam can enter the first transport channel 910. The output end of the first transport channel 910 extends obliquely upward. The input end of the first deflection magnet group 500 is connected to the first transport channel 910, and the connection between the first transport channel 910 and the first deflection magnet group 500 is tangent. Among them, the output end of the first transport channel 910 is arranged obliquely upward, so that the particle beam output from the first deflection magnet group 500 is above the rotation center line 14 of the rotation support device 200. Further optimized, a second focusing magnet 911 is provided on the outer periphery of the first transport channel 910.

[0083] In some embodiments, as Figure 10 shown, the first deflection magnet group 500 deflects the particle beam from the transport direction of the first transport channel 910 to the horizontal direction, that is, the direction of the particle beam output from the first deflection magnet group 500 is parallel to the horizontal plane or the support surface of the base. At this time, the second deflection magnet group 600 adopts four third deflection magnet bodies 610, thereby changing the particle beam from the horizontal direction to the vertical direction, which can simplify the structure of the particle beam treatment device, facilitate installation, and avoid the phenomenon that the angle between the first transport channel 910 and the reference object cannot be accurately positioned during installation, resulting in installation errors and further causing treatment accidents during the treatment of the particle beam treatment device. And this design method reduces the height of the first deflection magnet group 500 and the second deflection magnet group 600, thereby reducing the height of the overall particle beam treatment device and further saving the volume of the building accommodating the particle beam treatment device. It should be noted that this design method should satisfy that the irradiation head 800 is above the rotation center line 14 of the rotation support device 200, and there is a certain distance between the irradiation head 800 and the rotation center line 14 of the rotation support device 200 to accommodate the patient.

[0084] In some other embodiments, if the space between the irradiation head 800 and the rotation center line 14 of the rotation support device 200 is insufficient to accommodate a patient, the output end of the first deflection magnet group 500 is inclined obliquely upward. Specifically, the included angle between the first delivery channel 910 and the plane where the synchrotron 400 is located can be changed, or the central angle of the particle beam trajectory of the first deflection magnet group 500 can be increased while keeping the plane of the first deflection magnet group 500 relatively unchanged with respect to the synchrotron 400, so as to change the beam direction of the output end of the first deflection magnet group 500, and further make the output end of the first deflection magnet group 500 inclined obliquely upward. The included angle between the plane where the first deflection magnet group 500 is located and the horizontal plane is β. At this time, the rotation angle of the second deflection magnet group 600 is 90° + β. In order to ensure that the output end of the second deflection magnet group 600 points to the rotation center line 14 of the rotation support device 200, the length of the second delivery channel 900 can be adjusted. This design method increases the distance between the irradiation head 800 and the rotation center line 14 of the rotation support device 200 to meet the design requirements. Further optimized, the included angle β between the plane where the first deflection magnet group 500 is located and the horizontal plane is less than or equal to 30°. The smaller the included angle β, the lower the overall height of the particle beam treatment device. The included angle β is designed according to the orientation of the output end of the second delivery channel 900 to ensure that the output end of the second delivery channel 900 points to the rotation center line 14 of the rotation support device 200.

[0085] In some other embodiments, in order to increase the distance between the irradiation head 800 and the rotation center line 14 of the rotation support device 200, the length of the first delivery channel 910 can also be adjusted. Of course, the length of the first delivery channel 910 should not be too short or too long and should be within the design range. Correspondingly, the rotation angle of the first deflection magnet group 500, the rotation angle of the second deflection magnet group 600, and the length of the first delivery pipeline are adjusted according to the orientation of the output end of the second deflection magnet group 600 to ensure that the output end of the second deflection magnet group 600 points to the rotation center line 14 of the rotation support device 200.

[0086] Combined with Figure 5 、 Figure 6 and Figure 12As shown, in this embodiment, the particle beam therapy device further includes a cylinder 220, which is a cylinder and is coaxially fixed with the rotating support device 200. The first deflection magnet group 500, the second delivery channel 900 and part of the second deflection magnet group 600 are located outside the cylinder 220, and the output end of the second deflection magnet group 600 passes through the side wall of the cylinder 220 and is inserted into the inside of the cylinder 220. The second deflection magnet group 600 is fixedly connected to the cylinder 220, thereby enhancing the stability of the second deflection magnet group 600, and the cylinder 220 also plays a role of physical isolation. In order to increase the stability of each device of the particle beam therapy device during the rotation process, a connecting arm or a connecting frame can be set on the outer periphery of the cylinder 220, and the first deflection magnet group 500, the second deflection magnet group 600, the first delivery channel 910, the second delivery channel 900, the irradiation head 800 and a plurality of focusing magnets are connected and fixed by the connecting arm or the connecting frame.

[0087] In other embodiments, when the axial length of the particle beam therapy device is small, it is not necessary to set the cylinder 220. In this case, the first deflection magnet group 500, the second deflection magnet group 600, the first delivery channel 910, the second delivery channel 900, the irradiation head 800 and the multiple focusing magnets need to be fixedly connected by a fixed connection device to increase the stability of the rotation process. The fixed connection device can also be a connecting arm or a connecting frame. Since the connecting arm and the connecting frame are both common in the prior art and their setting methods are diverse, they only need to be able to play a connecting and fixing role, so they are not described in detail in this embodiment.

[0088] Combination Figure 5 and Figure 12 As shown, the rotating support device 200 and the cylinder 220 are supported by the first support 110 and the second support 120. In some optional embodiments, the cylinder 220 can be a square cylinder, an elliptical cylinder or a prismatic cylinder. Of course, the cylinders 220 of these shapes will also be provided with cylindrical matching parts adapted to the arc tracks of the first support 110 and the second support 120.

[0089] It should be noted that, in this patent, the particle beam motion trajectory in the deflection magnet body or the deflection magnet group or the synchrotron 400 or the transport channel does not necessarily remain unchanged. In addition, when there are multiple deflection magnet bodies in the synchrotron 400 and the first deflection magnet group 500 or the second deflection magnet group 600, the beam motion trajectory in the connecting channel between the deflection magnet bodies is not necessarily an arc, so the center angle of the deflection magnet group mentioned in this patent is the center angle of a virtual arc, which is fitted by the motion trajectory of the beam in each deflection magnet body in the deflection magnet group.

[0090] In this document, relational terms such as "first" and "second" are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any actual relationship or order between these entities or operations. Moreover, the term "comprising", "including" or any other variation thereof is intended to cover non-exclusive inclusion, such that a process, method, article or device comprising a series of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such process, method, article or device. Without further limitation, an element defined by the statement "comprising an..." does not exclude the presence of additional identical elements in the process, method, article or device comprising the element.

[0091] The above are only specific embodiments of the present disclosure, enabling those skilled in the art to understand or implement the present disclosure. Various modifications to these embodiments will be obvious to those skilled in the art, and the general principles defined herein can be implemented in other embodiments without departing from the spirit or scope of the present disclosure. Therefore, the present disclosure will not be limited to these embodiments described herein, but rather to the broadest scope consistent with the principles and novel features disclosed herein.

Claims

1. A particle beam therapy device for emitting a particle beam towards a target tissue, characterized in that, it comprises: A fixed support device (100), including a base, on which a driving rotation mechanism is provided for serving as a support foundation; A synchrotron (400) for accelerating the particle beam, in which there is a deflection magnet in the synchrotron (400), and a first delivery channel (910) is connected to the synchrotron (400), and the first delivery channel (910) delivers the particle beam obliquely upwards; A rotating support device (200) for supporting the synchrotron (400), and the rotating support device (200) is rotatably arranged on the fixed support device (100); when the rotating support device (200) makes a rotational movement, it has a rotation center line (14), and the power provided by the driving rotation mechanism can make the rotating support device (200) rotate around the rotation center line (14); A first deflection magnet group (500), arranged on the rotating support device (200), for receiving and delivering the particle beam output from the first delivery channel (910), the first deflection magnet group (500) is arc-shaped, and the particle beam output from the first delivery channel (910) enters the first deflection magnet group (500) along the tangent direction of the input end of the first deflection magnet group (500); A second deflection magnet group (600), connected to the first deflection magnet group (500), for receiving and transmitting the particle beam output from the first deflection magnet group (500), the second deflection magnet group (600) is arc-shaped, and the particle beam output from the first deflection magnet group (500) enters the second deflection magnet group (600) along the tangent direction of the input end of the second deflection magnet group (600), and the output end of the second deflection magnet group (600) points to the rotation center line (14) of the rotating support device (200); An irradiation head (800), connected to the end of the second deflection magnet group (600), and the particle beam is emitted from the irradiation head (800) to the target tissue; wherein, the output end of the first deflection magnet group (500) is connected to the input end of the second deflection magnet group (600) through a second delivery channel (900), and the second delivery channel (900) is tangent to the connection parts of the first deflection magnet group (500) and the second deflection magnet group (600); The input end of the first deflection magnet group (500) is connected to the first delivery channel (910), and the first delivery channel (910) is tangent to the connection part of the first deflection magnet group (500).

2. The particle beam therapy device according to claim 1, characterized in that, A first focusing magnet (901) is provided on the outer periphery of the second delivery channel (900).

3. The particle beam therapy device according to claim 1, characterized in that, An included angle is formed between the plane where the first deflection magnet group (500) is located and the plane where the second deflection magnet group (600) is located.

4. The particle beam therapy device according to claim 1, characterized in that, a second focusing magnet (911) is provided on the outer periphery of the first transport channel (910).

5. The particle beam therapy device according to claim 1, characterized in that, the plane in which the first deflection magnet group (500) is located is coplanar with the plane in which the second deflection magnet group (600) is located.

6. The particle beam therapy device according to claim 1 or 5, characterized in that, at least part of the structure or parameters of the first deflection magnet group (500) and the second deflection magnet group (600) are the same as those of the deflection magnet group in the synchrotron (400).

7. The particle beam therapy device according to claim 1 or 5, characterized in that, the structure and parameters of the deflection magnet body in the second deflection magnet group (600) are the same as those of the deflection magnet body in the deflection magnet group in the synchrotron (400), and the number of the deflection magnet bodies in the second deflection magnet group (600) is the same as the number of the deflection magnet bodies in the deflection magnet group in the synchrotron (400).

8. The particle beam therapy device according to claim 1, characterized in that, the output end of the first deflection magnet group (500) is inclined obliquely upward, so that the angle between the plane in which the first deflection magnet group (500) is located and the horizontal plane is β, and the rotation angle of the second deflection magnet group (600) is 90° + β.

9. The particle beam therapy device according to claim 8, characterized in that, the angle β between the plane in which the first deflection magnet group (500) is located and the horizontal plane is less than or equal to 30°.

10. The particle beam therapy device according to claim 1, characterized in that, the radius of curvature of the deflection part formed by the deflection magnets in the first deflection magnet group (500) and the second deflection magnet group (600) is the same as the radius of curvature of the deflection part formed by the deflection magnets in the synchrotron (400).

11. The particle beam therapy device according to claim 1, characterized in that, the particle beam output from the second deflection magnet group (600) is perpendicular to the rotation center line (14) of the rotation support device (200).

12. The particle beam therapy device according to claim 1, characterized in that, the rotation center line (14) of the rotation support device (200) is arranged in the horizontal direction or is parallel to the support surface of the base.

13. The particle beam therapy device according to claim 1, characterized in that, the direction of the particle beam output from the first deflection magnet group (500) is parallel to the horizontal plane or the support surface of the base.

14. The particle beam therapy device according to claim 1, characterized in that, the plane (10) in which the particle beam movement trajectory is located in the synchrotron (400) is perpendicular to the support surface of the base or the horizontal plane.

15. The particle beam therapy device according to claim 1, characterized in that, Both sides of the rotary support device (200) are provided with an annular structure. The annular structure is coaxial with the rotary support device (200). The annular structure is rotatably arranged on the fixed support device (100), and the outer diameter of the annular structure is smaller than the radial distance of the outermost point of the rotary support device (200) in the radial direction.

16. The particle beam therapy device according to claim 1, characterized in that the deflection magnet bodies in the first deflection magnet group (500), the deflection magnet bodies in the second deflection magnet group (600), and the deflection magnet bodies in the deflection magnet group in the synchrotron (400) all have focusing edges.

17. The particle beam therapy device according to claim 1, characterized in that the vertical plane (13) between the particle beam movement trajectory in the first transport channel (910) and the plane where the particle beam movement trajectory in the synchrotron (400) is located is perpendicular to the horizontal plane or the support surface of the base.

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