A method, system, device and readable storage medium for building a model of a bone structure prosthesis

Abstract

The present invention discloses a model construction method, system, device and readable storage medium of a bone structure prosthesis, the method comprising: obtaining a bone image collected by a preset device; determining at least one region in the bone image whose grayscale value meets a predetermined threshold range; constructing a void distribution of a crystal structure according to the distribution of at least one region in the bone image; and constructing a model of the bone structure prosthesis according to the void distribution of the crystal structure. A bone structure prosthesis can be made by the model. The elastic modulus of the bone structure prosthesis made according to the model matches the elastic modulus of the bone in the bone image, which solves the technical problem in the prior art that the bone structure prosthesis does not match the elastic modulus of the bone implanted in the human body, resulting in a stress shielding effect of the bone structure prosthesis, causing bone absorption, and then loosening the bone structure prosthesis, and the bone structure prosthesis fails to be implanted.

Description

Technical Field

[0001] The present invention relates to the field of medical devices, and in particular to a model building method, system, device and readable storage medium of a bone structure prosthesis. Background Art

[0002] At present, the implantation of bone structure prosthesis is a conventional treatment option for joints, spine and the like. Among them, bone structure prosthesis is a solid structure produced by casting and forging in the prior art. The elastic modulus of human bones needs to be taken into account in the structural design of bone structure prosthesis. The elastic modulus of each person's bones is different, and even different bones of the same person may have different elastic moduli. If the elastic modulus of the bone structure prosthesis is different from that of the human bone, it will cause the stress shielding effect of the bone structure prosthesis after implantation into the human body, causing bone absorption, and then loosening the bone structure prosthesis, resulting in failure of bone structure prosthesis implantation.

[0003] Therefore, the inventors have discovered that there are at least the following problems in the prior art: since the elastic modulus of each individual bone is different, if the elastic modulus of the bone structure prosthesis does not match the elastic modulus of the human bone, it will lead to a stress shielding effect of the bone structure prosthesis implanted in the human body, causing bone absorption, and further loosening of the bone structure prosthesis, resulting in technical problems such as failure of bone structure prosthesis implantation. Summary of the invention

[0004] The present application provides a method for constructing a model of a bone structure prosthesis, the purpose of which is to obtain a model that matches the elastic modulus of the bone captured in the bone image, for use in making a corresponding bone structure prosthesis, so that the elastic modulus of the manufactured bone structure prosthesis matches the elastic modulus of the bone captured in the bone image.

[0005] The method includes:

[0006] acquiring a bone image acquired by a preset device;

[0007] Determine at least one region in the bone image whose grayscale value meets a predetermined threshold range;

[0008] constructing a void distribution of a crystal structure according to the distribution of at least one of the regions in the bone image, wherein the crystal structure is a structure disposed on the bone structure prosthesis for controlling the elastic modulus of the bone structure prosthesis;

[0009] A model of the bone structure prosthesis is constructed according to the void distribution of the crystal structure.

[0010] Optionally, constructing the void distribution of the crystal structure according to the distribution of at least one of the regions in the bone image, wherein the crystal structure is a structure disposed on the bone structure prosthesis for controlling the elastic modulus of the bone structure prosthesis, comprises:

[0011] Selecting a point in each of the regions according to a first predetermined method;

[0012] According to the positions of the points in the bone image, a segmentation line between adjacent points is constructed in a second predetermined manner;

[0013] Constructing a truss structure according to the dividing line, wherein the truss structure is a spatial structure formed by a plurality of connecting rods connected to each other, and the spatial position of the connecting rod is set corresponding to the spatial position of the dividing line;

[0014] The void distribution between the plurality of connecting rods is regarded as the void distribution of the crystal structure.

[0015] Optionally, selecting a point in the region according to the first predetermined method is selecting an extreme point of the grayscale value of the region as the selected point.

[0016] Optionally, the dividing line is a perpendicular bisector between adjacent points.

[0017] The present application also provides a method for manufacturing a bone structure prosthesis, which comprises manufacturing the bone structure prosthesis by 3D printing according to a model.

[0018] The present application also provides a system for manufacturing a bone structure prosthesis, the system comprising: a presetting device and a computing and processing device, and a manufacturing device;

[0019] The preset device is used to collect the bone image;

[0020] The operation processing device is used to obtain a bone image collected by a preset device; determine at least one area in the bone image whose grayscale value meets a predetermined threshold range; construct a void distribution of a crystal structure according to the distribution of at least one of the areas in the bone image, wherein the crystal structure is a structure arranged on the bone structure prosthesis for controlling the elastic modulus of the bone structure prosthesis; and construct a model of the bone structure prosthesis according to the void distribution of the crystal structure;

[0021] The manufacturing equipment is used to manufacture the bone structure prosthesis according to the model.

[0022] Optionally, the computing and processing device is also used to select a point in each of the areas according to a first predetermined method; construct a dividing line between adjacent points according to the position of the point in the bone image in a second predetermined method; construct a truss structure according to the dividing line, wherein the truss structure is a spatial structure formed by a plurality of interconnected connecting rods, and the spatial positions of the connecting rods are arranged corresponding to the spatial positions of the dividing lines; and use the distribution of gaps between the plurality of connecting rods as the distribution of gaps in a crystal structure.

[0023] The present application also provides a model building device for a bone structure prosthesis, the device comprising:

[0024] A preset device for collecting bone images;

[0025] An acquisition module, used for acquiring a bone image collected by a preset device;

[0026] A determination module, used to determine at least one region in the bone image whose grayscale value meets a predetermined threshold range;

[0027] A construction module is used to construct the void distribution of the crystal structure according to the distribution of at least one of the regions in the bone image, wherein the crystal structure is a structure arranged on the bone structure prosthesis for controlling the elastic modulus of the bone structure prosthesis; and a model of the bone structure prosthesis is constructed according to the void distribution of the crystal structure.

[0028] The present application also provides a model building device for a bone structure prosthesis, the device also comprising:

[0029] A selection module, used for selecting a point in each of the regions according to a first predetermined method;

[0030] The construction module is used to construct a dividing line between adjacent points in a second predetermined manner according to the positions of the points in the bone image; construct a truss structure according to the dividing line, wherein the truss structure is a spatial structure formed by a plurality of interconnected connecting rods, and the spatial positions of the connecting rods are arranged corresponding to the spatial positions of the dividing lines; and use the gap distribution between the plurality of connecting rods as the gap distribution of the crystal structure.

[0031] The present application also provides a device for building a model of a bone structure prosthesis, the device comprising: a processor and a memory;

[0032] The memory stores an application program executable by the processor, which is used to enable the processor to execute the steps of the method for building a model of a bone structure prosthesis.

[0033] The present application also provides a computer-readable storage medium having a computer program stored thereon, which implements the steps of the bone structure prosthesis model building method when executed by a processor.

[0034] As can be seen above, based on the above embodiment, a bone image collected by a preset device is obtained, and a corresponding model is constructed according to the spatial distribution of the structure in the image. Finally, the required bone structure prosthesis is produced through the model. The crystal structure provided on the bone structure prosthesis can accurately simulate the elastic modulus of different human bones, thereby solving the technical problem in the prior art that the elastic modulus of the bone structure prosthesis does not match the elastic modulus of the bone implanted in the human body, resulting in a stress shielding effect of the bone structure prosthesis, causing bone absorption, and further loosening of the bone structure prosthesis, resulting in failure of bone structure prosthesis implantation. BRIEF DESCRIPTION OF THE DRAWINGS

[0035] Figure 1 A schematic diagram of a process 100 of a method for building a model of a bone structure prosthesis in one embodiment of the present invention;

[0036] Figure 2 A schematic diagram of a process 200 of a method for building a model of a bone structure prosthesis according to an embodiment of the present invention;

[0037] Figure 3 A schematic diagram of a bone image in an embodiment of the present invention;

[0038] Figure 4 A schematic diagram of a point selected in a bone image in an embodiment of the present invention;

[0039] Figure 5 A schematic diagram of a skeleton image after a segmentation line is constructed in an embodiment of the present invention;

[0040] Figure 6 A schematic diagram of a model in one embodiment of the present invention;

[0041] Figure 7 Schematic diagram of the structure of a device for building a model of a bone structure prosthesis in one embodiment of the present invention. DETAILED DESCRIPTION

[0042] In order to make the objectives, technical solutions and advantages of the present invention more clearly understood, the present invention is further described in detail below with reference to the accompanying drawings and embodiments.

[0043] In some embodiment scenarios, a crystal structure similar to trabecular bone can be set on the bone structure prosthesis. The crystal structure can be roughly understood as a spatial structure overlapped by different connecting rods. The elastic modulus of the bone structure prosthesis is related to the spatial position of the spatial connecting rod and the diameter of the connecting rod. The spatial position of the connecting rod can be indirectly obtained by the distribution of the gaps between the connecting rods. As long as the material of the spatial gap is removed physically, the remaining part is equivalent to the spatial position of the connecting rod. The trabecular structure in the skeleton of an organism is the same as the above-mentioned crystal structure and has good mechanical and biological properties. The trabecular structure in the skeleton can adjust the stress state according to the load, and the structure is mimicked and set on the bone structure prosthesis. In fact, the trabecular structure on the skeleton is an important cause of the elastic modulus of the skeleton.

[0044] In some embodiments, the bone structure prosthesis generates a crystalline structure similar to trabecular bone on the surface of the implant by chemical vapor deposition (CVD refers to a method in which chemical gases or vapors react on the surface of a matrix to synthesize coatings or nanomaterials).

[0045] Figure 1 FIG. 1 is a schematic diagram of a process 100 of a method for constructing a model of a bone structure prosthesis in one embodiment of the present invention. Figure 1 As shown, in one embodiment, the present application provides a method for constructing a model of a bone structure prosthesis, the method comprising:

[0046] S101, acquiring a bone image collected by a preset device;

[0047] In this step, first a bone image is collected by a preset device. This step can be understood as scanning the image of the bone based on the CT of clinical medical imaging, thereby obtaining the bone image. It should be pointed out that what the CT machine scans is the bone image of different sections of the bone, and the bone image in the present application can be the image of different sections, or it can be the three-dimensional image obtained after the bone scan, and with regard to the bone image obtained by the CT machine scan, the three-dimensional bone image can also be generated after the bone images of different sections are superimposed.

[0048] S102, determining at least one region in the bone image whose grayscale value meets a predetermined threshold range;

[0049] In this step, at least one region is determined by using different grayscales and predetermined thresholds of the bone image. In the imaging of the bone image, since the distribution of the grid structure crystal structure voids in the trabecular structure of the bone will be shown with different light and dark representations on the imaging, the grayscale on the bone image will produce a drop in grayscale, and the region on the bone image where it is located can be determined by this drop is the distribution of the voids. The predetermined threshold is the grayscale value range of the voids in the trabecular structure. During CT imaging, the grayscale value of the void is relatively low relative to the grayscale value of the part with the bone structure (corresponding to the connecting rod in the crystal structure), so a range can be specified by a predetermined threshold, such as when it is less than the predetermined threshold, it is judged that the corresponding region of the bone image is the void region in the trabecular structure (i.e., the void region in the crystal structure). Of course, the distribution of bone structure in the trabecular structure can also be reflected by the grayscale value, relative to the connecting rod distribution in the crystal structure. For example, when the grayscale value is greater than a predetermined threshold, the non-void parts in the trabecular structure are found, and the areas corresponding to these parts are the parts of the bone structure, that is, the connecting rod parts of the crystal structure. It is also possible to use the non-void parts for subsequent processing. The specific processing steps will be explained in the subsequent steps.

[0050] S103, constructing a void distribution of a crystal structure according to the distribution of at least one of the regions in the bone image, wherein the crystal structure is a structure disposed on the bone structure prosthesis for controlling the elastic modulus of the bone structure prosthesis;

[0051] In this step, a crystal structure is constructed according to the region determined in the previous step. The crystal structure is used to fit the reticular crystal structure of the trabecular structure. The crystal structure is arranged on the bone structure prosthesis, and the reticular structure is fitted through the gaps in the space. In other words, the trabecular structure in the bone is simulated by the crystal structure, and the distribution relationship of the crystal structure gaps in the space is matched with the gap distribution of the trabecular structure in the real bone image. Finally, the elastic modulus of the bone in the bone image is simulated. Of course, it should be pointed out that there are other structures on the bone structure prosthesis, which will be arranged according to the specific implanted bone effect. This application does not discuss other structures here. Only the elastic modulus matching of the crystal structure to the bone structure prosthesis is discussed. When the crystal structure of the bone structure prosthesis corresponds to the trabecular structure of the bone in the bone image, after the elastic modulus of the bone in the bone image is matched, a model of the bone structure prosthesis corresponding to the elastic modulus can be generated. The bone structure prosthesis made by the model has an elastic modulus that matches the elastic modulus of the bone in the bone image.

[0052] In this embodiment, firstly, a bone image collected by a preset device is obtained. The bone image can be obtained by scanning the human body through a preset device such as a CT machine. It should be noted that the bone image here can be a cross-sectional bone image of the bone, or a three-dimensional stereoscopic image, and then multiple regions that meet the predetermined threshold range are determined by the grayscale in the bone image. It should be noted that the region here can be a region representing the voids in the trabecular structure of the bone or a region of the bone structure. The void space distribution of the crystal structure is obtained according to the distribution of these regions in space. The model constructed according to the void space distribution of the crystal structure can be used to make a bone structure prosthesis, and the elastic modulus of the bone prosthesis can be matched with the elastic modulus in the bone image. The technical problem that the bone structure prosthesis in the prior art does not match the elastic modulus of the bone implanted in the human body, resulting in the stress shielding effect of the bone structure prosthesis, causing bone absorption, and then loosening the bone structure prosthesis, and the bone structure prosthesis implantation failure is solved.

[0053] Figure 2 FIG. 2 is a schematic diagram of a process 200 of a method for constructing a model of a bone structure prosthesis in one embodiment of the present invention. Figure 2 As shown, in one embodiment, the void distribution of the crystal structure is constructed according to the distribution of at least one of the regions in the bone image, wherein the crystal structure is a structure disposed on the bone structure prosthesis for controlling the elastic modulus of the bone structure prosthesis, and includes:

[0054] S201, selecting a point in each area according to a first predetermined method;

[0055] In this step, a point can be selected from each area, whether it is a two-dimensional plane bone image obtained by CT scanning or a three-dimensional bone image obtained by scanning through other preset devices, a point can be selected from the area determined in the two-dimensional plane bone image or the three-dimensional bone image. Because the area should be presented as a surface or body in the bone image, its essence is a set composed of multiple points in the geometric space. Since it is a region determined by a predetermined threshold range, the first predetermined method can be to select the extreme point in the region. As mentioned above, taking the implementation method of the region representing the void in the trabecular structure as an example, the void can be set in the imaging of the bone image in a manner that the grayscale value is lower than the bone structure. Then the grayscale value minimum point in the region in the bone image can be selected as the point selected in the region for subsequent processing. Figure 3 is a schematic diagram of a bone image in an embodiment of the present invention, Figure 4 FIG. 1 is a schematic diagram of a bone image after selecting a point in an embodiment of the present invention. Figure 3 and Figure 4 shown.

[0056] Of course, the first predetermined method may also be implemented by using a point at the geometric center of the gap, which will not be enumerated here.

[0057] S202, constructing a segmentation line between adjacent points in a second predetermined manner according to the positions of the points in the bone image;

[0058] Figure 5 FIG. 1 is a schematic diagram of a skeleton image after a segmentation line is constructed in an embodiment of the present invention. Figure 5 As shown, in this step, a dividing line is constructed between adjacent selected points, which is used as the basis for the subsequent construction of the truss structure. The second predetermined method can adopt the Voronoi method, but is not limited to the specific method of Voronoi. The Voronoi diagram, also known as the Thiessen polygon or the Dirichlet diagram, is composed of a set of continuous polygons composed of perpendicular bisectors of straight lines connecting two adjacent points. N points that are distinct on a plane divide the plane according to the nearest neighbor principle; each point is associated with its nearest neighbor area.

[0059] S203, constructing a truss structure according to the dividing line, wherein the truss structure is a spatial structure formed by a plurality of connecting rods connected to each other, and the spatial positions of the connecting rods are arranged corresponding to the spatial positions of the dividing line;

[0060] In this step, the segmentation line is constructed as a truss structure. For example, the segmentation line can be used as a connecting rod of the truss structure. Then, the gap distribution of the truss structure in space will correspond to the gap distribution in the bone image. The method of constructing a truss structure through a segmentation line can also refer to the spatial application method of Voronoi. Similarly, the method of constructing a three-dimensional truss structure is not limited to the Voronoi method.

[0061] S204, taking the gap distribution between the plurality of connecting rods as the gap distribution of the crystal structure.

[0062] In this step, a truss structure is used as the crystal structure.

[0063] In this embodiment, a specific implementation method of constructing a model through the distribution of regions in a bone image is provided, points are selected from the region, and then segmentation lines are constructed between adjacent points. A truss structure is then constructed in space based on these segmentation lines, and the truss structure is used as a crystal structure.

[0064] Taking a layer of bone image in clinical CT as an example, the bone image obtains the corresponding grayscale value according to the pixel point, compares the grayscale value corresponding to the pixel point with the predetermined threshold range, and determines the area that meets the predetermined threshold range. Taking the area representing the gap of the crystal structure as an example, the area with lower grayscale value in the bone image of CT is the area of ​​the gap in the trabecular structure, so these areas with lower grayscale value will present a block distribution in the bone image, and the grayscale value is set to a specific value less than a certain threshold. The value less than the specific value can be understood as the predetermined threshold range, so that the gap in the bone image can be determined. The determined gap corresponding area is essentially a minimum value point set (i.e., the position of multiple corresponding pixel points less than the predetermined threshold in the bone image). In each area, select the point with the smallest grayscale value (i.e., the minimum value point). If there are multiple points with the same minimum grayscale value in a certain area, one of them can be selected randomly or in other ways. Then, these points are divided into blocks by the dividing lines between adjacent points in the bone image scanned by the CT machine. These divided blocks are convex polygons, and if it is a three-dimensional bone image, it is a polygon. It should be pointed out that if a multi-layer bone scan is performed by a CT machine to obtain a multi-layer bone image, a three-dimensional model can be formed by stacking these bone images, then the above method can still be used on the area in space, and a three-dimensional polygonal block can also be constructed. The specific algorithm can adopt the Voronoi method.

[0065] In one embodiment, selecting a point in the region according to the first predetermined method is selecting an extreme point of the grayscale value of the region as the selected point.

[0066] In this embodiment, a specific implementation method for selecting points is provided.

[0067] In one embodiment, the dividing line is a perpendicular bisector between adjacent points.

[0068] In this embodiment, a specific implementation method for constructing a segmentation line is provided.

[0069] The present application also provides a method for manufacturing a bone structure prosthesis, which is to manufacture a bone structure prosthesis by 3D printing according to a model.

[0070] This embodiment provides a specific implementation method of making a bone structure prosthesis through a model, that is, a 3D printing method. Since the trabecular structure is very complex, even if a model can be generated, the processing method in the prior art is very difficult, because in the prior art, whether it is machining or mold manufacturing technology, it is difficult to produce a crystal structure with such a complex internal structure, and since each person's model may be different, it is difficult to mass produce.

[0071] Therefore, additive manufacturing (3D printing) can effectively solve this problem. 3D printing is a process of printing layer by layer after the material is melted by a nozzle, so its advantage is to build its internal crystal structure and provide more compatible metals, fusions, ceramics and other materials, making manufacturing efficient and low-cost.

[0072] The preferred method is to use 3D printing to produce titanium alloy powder through melting process, which is very suitable for complex structure, high porosity and customized production requirements.

[0073] In one embodiment, the present application also provides a system for manufacturing a bone structure prosthesis, the system comprising: a presetting device and a computing and processing device, and a manufacturing device;

[0074] The preset device is used to collect the bone image;

[0075] The operation processing device is used to obtain a bone image collected by a preset device; determine at least one area in the bone image whose grayscale value meets a predetermined threshold range; construct a void distribution of a crystal structure according to the distribution of at least one of the areas in the bone image, wherein the crystal structure is a structure arranged on the bone structure prosthesis for controlling the elastic modulus of the bone structure prosthesis; and construct a model of the bone structure prosthesis according to the void distribution of the crystal structure;

[0076] The manufacturing equipment is used to manufacture the bone structure prosthesis according to the model.

[0077] In one embodiment, the computing and processing device is also used to select a point in each of the areas according to a first predetermined method; construct a dividing line between adjacent points according to the position of the point in the bone image by a second predetermined method; construct a truss structure according to the dividing line, wherein the truss structure is a spatial structure formed by a plurality of interconnected connecting rods, and the spatial positions of the connecting rods are arranged corresponding to the spatial positions of the dividing lines; and use the distribution of gaps between the plurality of connecting rods as the distribution of gaps in the crystal structure.

[0078] Figure 7 FIG. 1 is a schematic diagram of the structure of a device for building a model of a bone structure prosthesis in one embodiment of the present invention. Figure 7 As shown, in one embodiment, the present application also provides a model building device for a bone structure prosthesis, the device comprising:

[0079] Presetting device 101, used for collecting bone images;

[0080] An acquisition module 102 is used to acquire a bone image collected by a preset device;

[0081] A determination module 103 is used to determine at least one region in the bone image whose grayscale value meets a predetermined threshold range;

[0082] The construction module 104 is used to construct the void distribution of the crystal structure according to the distribution of at least one of the regions in the bone image, wherein the crystal structure is a structure arranged on the bone structure prosthesis for controlling the elastic modulus of the bone structure prosthesis; and construct a model of the bone structure prosthesis according to the void distribution of the crystal structure.

[0083] In one embodiment, the present application further provides a model building device for a bone structure prosthesis, the device further comprising:

[0084] A selection module 105, configured to select a point in each of the regions according to a first predetermined method;

[0085] The construction module 104 is used to construct a dividing line between adjacent points in a second predetermined manner according to the positions of the points in the bone image; construct a truss structure according to the dividing line, wherein the truss structure is a spatial structure formed by a plurality of connecting rods connected to each other, and the spatial positions of the connecting rods are arranged corresponding to the spatial positions of the dividing line; and use the gap distribution between the plurality of connecting rods as the gap distribution of the crystal structure.

[0086] In one embodiment, the present application also provides a device for manufacturing a bone structure prosthesis, the device comprising: a processor and a memory;

[0087] The memory stores an application program executable by the processor, which is used to enable the processor to execute the steps of the method for building a model of a bone structure prosthesis.

[0088] In one embodiment, the present application provides a computer-readable storage medium having a computer program stored thereon, which, when executed by a processor, implements the steps of the method for building a model of a bone structure prosthesis.

[0089] Figure 6 Schematic diagram of a model in one embodiment of the present invention. Figure 6 As shown, in one embodiment, the present application also provides a crystal structure of a bone structure prosthesis, the crystal structure comprising a plurality of crystal units, and the plurality of crystal units are stacked on each other;

[0090] The crystal unit includes a plurality of connecting rods, and the plurality of connecting rods are interwoven to form a three-dimensional truss structure.

[0091] Optionally, two ends of the plurality of connecting rods of the crystal unit are connected to each other and formed as one piece.

[0092] Those skilled in the art will appreciate that the features described in the various embodiments and / or claims of the present disclosure may be combined and / or combined in a variety of ways, even if such combinations or combinations are not explicitly described in the present application. In particular, without departing from the spirit and teachings of the present application, the features described in the various embodiments and / or claims of the present application may be combined and / or combined in a variety of ways, and all of these combinations and / or combinations fall within the scope disclosed in the present application.

[0093] Specific embodiments are used herein to illustrate the principles and implementation methods of the present invention. The description of the above embodiments is only used to help understand the method of the present invention and its core ideas, and is not used to limit the present application. For those skilled in the art, changes can be made in the specific implementation methods and application scopes according to the ideas, spirits and principles of the present invention, and any modifications, equivalent substitutions, improvements, etc. made therein should be included in the scope of protection of this application.

Claims

1. A method for constructing a model of a bone structure prosthesis, characterized in that: The method includes: acquiring a bone image acquired by a preset device; Determine at least one region in the bone image whose grayscale value meets a predetermined threshold range; constructing a void distribution of a crystal structure according to the distribution of at least one of the regions in the bone image, wherein the crystal structure is a structure disposed on the bone structure prosthesis for controlling the elastic modulus of the bone structure prosthesis; constructing a model of the bone structure prosthesis according to the void distribution of the crystal structure; Wherein, the void distribution of the crystal structure is constructed according to the distribution of at least one of the regions in the bone image, wherein the crystal structure is a structure arranged on the bone structure prosthesis for controlling the elastic modulus of the bone structure prosthesis, and includes: Selecting a point in each of the regions according to a first predetermined method; According to the positions of the points in the bone image, a segmentation line between adjacent points is constructed in a second predetermined manner; Constructing a truss structure according to the dividing line, wherein the truss structure is a spatial structure formed by a plurality of connecting rods connected to each other, and the spatial position of the connecting rod is set corresponding to the spatial position of the dividing line; The void distribution between the plurality of connecting rods is regarded as the void distribution of the crystal structure.

2. The method for constructing a model of a bone structure prosthesis according to claim 1, characterized in that: The selecting a point in the region according to the first predetermined method is selecting an extreme point of the grayscale value of the region as the selected point.

3. The method for constructing a model of a bone structure prosthesis according to claim 1, characterized in that: The dividing line is a perpendicular bisector between adjacent points.

4. A method for manufacturing a bone structure prosthesis, characterized in that: The manufacturing method is to manufacture a bone structure prosthesis by 3D printing according to a model, wherein the model is a model of the bone structure prosthesis involved in the model construction method described in any one of claims 1 to 3.

5. A model building device for a bone structure prosthesis, characterized in that: The device includes: A preset device for collecting bone images; An acquisition module, used for acquiring a bone image collected by a preset device; A determination module, used to determine at least one region in the bone image whose grayscale value meets a predetermined threshold range; A construction module, configured to construct a void distribution of a crystal structure according to the distribution of at least one of the regions in the bone image, wherein the crystal structure is a structure disposed on the bone structure prosthesis for controlling the elastic modulus of the bone structure prosthesis; and to construct a model of the bone structure prosthesis according to the void distribution of the crystal structure; The device further comprises: A selection module, used for selecting a point in each of the regions according to a first predetermined method; A construction module is used to construct a dividing line between adjacent points in a second predetermined manner according to the positions of the points in the bone image; construct a truss structure according to the dividing line, wherein the truss structure is a spatial structure formed by a plurality of connecting rods connected to each other, and the spatial positions of the connecting rods are arranged corresponding to the spatial positions of the dividing line; and use the gap distribution between the plurality of connecting rods as the gap distribution of the crystal structure.

6. A model building device for a bone structure prosthesis, characterized in that: The device comprises: a processor and a memory; The memory stores an application program executable by the processor, which is used to enable the processor to execute the steps of the method for building a model of a bone structure prosthesis according to any one of claims 1 to 3.

7. A computer-readable storage medium having a computer program stored thereon, characterized in that: When the program is executed by a processor, the steps of the method for building a model of a bone structure prosthesis according to any one of claims 1 to 3 are implemented.

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