A filling nitrogen system

The filling nitrogen system with real-time pressure monitoring and alarm functions addresses inconsistent nitrogen pressure, ensuring stable nitrogen levels and enhancing liquid medicine quality by stopping the filling process when pressure falls below set values.

CN112456427BActive Publication Date: 2024-12-20SPH NO 1 BIOCHEM & PHARMA CO LTD
View PDF 8 Cites 0 Cited by

Patent Information

Application Number
CN202011064611.4
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2020-09-30
Publication Date
2024-12-20
Estimated Expiration
2040-09-30

AI Technical Summary

Technical Problem

Existing liquid medicine filling systems fail to guarantee consistent nitrogen pressure across multiple production links, leading to uneven residual oxygen concentration in the filling process, affecting the quality of the liquid medicine.

Method used

A filling nitrogen system with digital electric contact pressure gauge, first and second pressure transmitters, and solenoid valves at the front and rear nitrogen filling stations, along with photoelectric sensors to monitor and adjust nitrogen pressure in real time, setting alarm values to ensure adequate pressure and stop the filling process if pressure drops below the set values.

Benefits of technology

Ensures consistent nitrogen pressure across all filling stations, preventing residual oxygen deviations and improving the quality of liquid medicine by stopping the filling process when pressure drops below set values.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure CN112456427B_ABST
    Figure CN112456427B_ABST
Patent Text Reader

Abstract

The invention provides a filling nitrogen charging system, comprising a front nitrogen charging station and a rear nitrogen charging station, wherein a digital electric contact pressure gauge is arranged on a general pipeline before nitrogen enters the front nitrogen charging station and the rear nitrogen charging station, and is used for real-time monitoring of the total nitrogen pressure on the front nitrogen charging station and the rear nitrogen charging station; a first flow meter, a first pneumatic diaphragm valve, a first solenoid valve and a first pressure transmitter are arranged at the front nitrogen charging station, and a second flow meter, a second pneumatic diaphragm valve, a second solenoid valve and a second pressure transmitter are arranged at the rear nitrogen charging station, and the nitrogen pressure on the pipeline on the front nitrogen charging station and the rear nitrogen charging station can be respectively adjusted by adjusting the nitrogen flow rate of the first and second flow meters; and the switching states of the first and second pneumatic diaphragm valves are respectively controlled by the first solenoid valve and the second solenoid valve. The present invention measures the nitrogen pressure in the three inflation pipelines in real time and sets a minimum pressure alarm value for the three inflation pipelines. When it is monitored that the pressure is lower than the alarm value, the filling nitrogen filling system turns on the alarm function, thereby ensuring that the nitrogen pressure is at a normal level during the filling process, eliminating the residual oxygen deviation of each liquid medicine bottle, and improving the quality of the liquid medicine.
Need to check novelty before this filing date? Find Prior Art

Description

Technical Field

[0001] The invention relates to the field of liquid medicine filling, and in particular to a filling and nitrogen charging system. Background Art

[0002] During the process of filling the liquid medicine, the medicine bottle generally needs to be processed by two processes: pre-filling and post-filling. Pre-filling means blowing a certain amount of nitrogen into the empty bottle before filling the liquid medicine to expel the oxygen inside as much as possible; post-filling means blowing enough nitrogen into the bottle after the liquid medicine is filled and before the wire drawing and sealing to ensure that there is no residual oxygen in the bottle environment before the medicine is sealed, thereby improving the stability of the medicine. Existing filling nitrogen filling systems such as Figure 1 As shown, a set of flowmeter, pneumatic diaphragm valve and solenoid valve are respectively configured at the front nitrogen filling station and the rear nitrogen filling station. The nitrogen pressure on the inflation pipeline can be adjusted by adjusting the nitrogen flow rate of the flowmeter. The state of each pneumatic diaphragm valve is controlled by the solenoid valve. When the solenoid valve is opened, the compressed air is controlled to be sent to the pneumatic switch valve, so that the pneumatic switch valve is opened. At this time, the inflation pipeline can be filled with the corresponding inflation gas, otherwise the inflation pipeline is in a closed state.

[0003] In the production process of liquid medicine, in addition to the nitrogen filling process, nitrogen is also needed in multiple processes such as CIP / SIP. The pressure of the nitrogen main tank flowing to the workshop is certain. If multiple links in the production workshop need to use nitrogen at the same time, the nitrogen pressure required by each link may not be guaranteed. When the nitrogen pressure of the nitrogen filling process of the medicine bottle is affected, the residual oxygen concentration in the filling bottle is uneven, which affects the quality of the liquid medicine. Summary of the invention

[0004] In view of the shortcomings of the prior art, the present application proposes a filling and nitrogen charging system.

[0005] The technical solution of the present invention is summarized as follows:

[0006] A filling nitrogen filling system comprises a front nitrogen filling station and a rear nitrogen filling station. A digital electric contact pressure gauge is arranged on the main pipeline before the nitrogen enters the front and rear nitrogen filling stations, which is used to monitor the total nitrogen pressure on the front and rear nitrogen filling stations in real time; a first flow meter, a first pneumatic diaphragm valve, a first solenoid valve and a first pressure transmitter are arranged at the front nitrogen filling station, and a second flow meter, a second pneumatic diaphragm valve, a second solenoid valve and a second pressure transmitter are arranged at the rear nitrogen filling station. The nitrogen pressure on the pipeline on the front and rear nitrogen filling stations can be adjusted respectively by adjusting the nitrogen flow rate of the first and second flow meters; the switch states of the first and second pneumatic diaphragm valves are controlled by the first solenoid valve and the second solenoid valve respectively.

[0007] The first pressure transmitter is provided with a first pressure alarm value, and the second pressure transmitter is provided with a second pressure alarm value. When the nitrogen filling pressure detected by the first pressure transmitter or the second pressure transmitter is lower than the corresponding pressure alarm value, the filling nitrogen filling system alarms.

[0008] The digital electric contact pressure gauge is provided with a third pressure alarm value. When it is detected that the nitrogen pressure is lower than the third pressure alarm value, the filling nitrogen charging system alarms.

[0009] The first pressure transmitter is located after the first pneumatic diaphragm valve on the front nitrogen filling station.

[0010] The second pressure transmitter is located before the second pneumatic diaphragm valve at the post-nitrogen filling station.

[0011] The second pneumatic diaphragm valve on the post-nitrogen filling station includes a pointer, and the position of the pointer is used to indicate whether the pneumatic valve is open.

[0012] A photoelectric sensor may be provided on the post-nitrogen filling pneumatic valve to detect the pointer position of the second pneumatic diaphragm valve and confirm whether the second pneumatic diaphragm valve is open.

[0013] A filling machine includes a filling and nitrogen filling system as described above. When the filling and nitrogen filling system alarms because the digital electric contact pressure gauge, the first pressure transmitter or the second pressure transmitter detects that the pressure is lower than its corresponding pressure alarm value, the filling machine alarms and stops the bottle feeding auger.

[0014] The present invention arranges a digital electric contact pressure gauge on the main pipeline before the nitrogen of the filling nitrogen filling system enters the front and rear nitrogen filling stations, and arranges a pressure transmitter on each of the two branch pipelines on the front and rear nitrogen filling stations, so as to measure the nitrogen pressure in the three filling pipelines in real time, and set a minimum pressure alarm value for the three filling pipelines. When the pressure is lower than the alarm value, the filling nitrogen filling system starts the alarm function, thereby ensuring that the nitrogen pressure is at a normal level during the filling process, eliminating the residual oxygen deviation of each liquid medicine bottle, and improving the quality of the liquid medicine. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative labor.

[0016] Figure 1 The invention relates to a filling and nitrogen charging system in the prior art.

[0017] Figure 2 It is the filling and nitrogen charging system in the present invention. DETAILED DESCRIPTION

[0018] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0019] like Figure 2 As shown, the filling nitrogen filling system of the present invention includes a front nitrogen filling station and a rear nitrogen filling station. A digital electric contact pressure gauge is arranged on the pipeline before the nitrogen enters the front and rear nitrogen filling stations. The pressure gauge can monitor the total nitrogen pressure at the front and rear nitrogen filling stations in real time. A set of flow meter, pneumatic diaphragm valve, solenoid valve and pressure transmitter are respectively configured at the front nitrogen filling station and the rear nitrogen filling station. The nitrogen flow rate of the flow meter can be adjusted to achieve the purpose of adjusting the nitrogen pressure on the inflation pipeline. The state of each pneumatic diaphragm valve is controlled by the solenoid valve. When the solenoid valve is opened, the compressed air is controlled to be sent to the pneumatic switch valve, so that the pneumatic switch valve is opened. At this time, the inflation pipeline can be filled with the corresponding inflation gas, otherwise the inflation pipeline is in a closed state.

[0020] In order to monitor the nitrogen pressure on each nitrogen filling pipeline in real time, a pressure transmitter is set at the front nitrogen filling station and the rear nitrogen filling station respectively. The front nitrogen filling station is used to blow a certain amount of nitrogen into the empty bottle before filling the liquid medicine. The pressure transmitter is set after the pneumatic diaphragm valve to monitor the nitrogen pressure in the filling pipeline when the pneumatic diaphragm valve is opened for nitrogen filling. When the bottle is filled with nitrogen after the liquid medicine is filled, if the nitrogen pressure is too high, it is easy to cause the liquid medicine in the bottle to splash out. The nitrogen pressure of the rear nitrogen filling station needs to be strictly controlled to be kept at a relatively low level. When the pneumatic diaphragm valve of the rear nitrogen filling station is opened, the nitrogen pressure in the pipeline is very small, resulting in the nitrogen pressure of the pipeline after the pneumatic diaphragm valve being too small to be easily measured by the pressure transmitter. Therefore, the pressure transmitter on the rear nitrogen filling station is set before the pneumatic diaphragm valve. By setting pressure transmitters at the front and rear nitrogen filling stations respectively, the nitrogen pressure value in the filling pipeline can be monitored in real time.

[0021] In the filling process of the workshop, in order to ensure the quality of the liquid medicine in the medicine bottle after production is completed, there are certain requirements for the nitrogen pressure of the front and rear nitrogen filling stations. Therefore, the digital electric contact pressure gauge is set with a minimum alarm value. When the nitrogen pressure value of the pressure gauge is lower than the minimum value, the system alarm function is turned on to remind the operator that the nitrogen pressure on the nitrogen filling pipeline is insufficient.

[0022] Furthermore, a corresponding alarm value is set for each pressure transmitter on the front and rear nitrogen filling stations. When the nitrogen pressure at any point on the front and rear filling pipelines is lower than its corresponding alarm value, the alarm function of the filling system is turned on.

[0023] At the post-nitrogen filling station, due to the low nitrogen filling pressure, the pressure transmitter is set before the pneumatic diaphragm valve to measure the nitrogen pressure before the pneumatic diaphragm valve in the charging pipeline. If the pneumatic diaphragm valve fails to open successfully, even if the pressure transmitter detection value is higher than the alarm value, the nitrogen pressure flowing into the liquid medicine bottle is still insufficient. Therefore, the status of the pneumatic diaphragm valve at the post-nitrogen filling station is monitored in real time. For example, a pneumatic valve with a pointer indication function can be selected to detect the pointer position to feedback whether the pneumatic valve is open.

[0024] Furthermore, when the above-mentioned digital electric contact pressure gauge of the nitrogen filling system or any pressure transmitter on the front and rear nitrogen filling stations alarms, in order to prevent the filled medicine bottles still remaining on the filling machine rail from flowing normally to the next station, the filling machine is also equipped with an alarm function. When any low pressure is detected and an alarm is sounded, the filling machine immediately alarms and stops the bottle feeding auger immediately. The bottles on the guide rail are not filled or sealed.

[0025] The present invention arranges a digital electric contact pressure gauge on the main pipeline before the nitrogen of the filling nitrogen filling system enters the front and rear nitrogen filling stations, and arranges a pressure transmitter on each of the two branch pipelines on the front and rear nitrogen filling stations, so as to measure the nitrogen pressure in the three filling pipelines in real time, and set the minimum pressure alarm value for the three filling pipelines. When the pressure is lower than the alarm value, the filling nitrogen filling system starts the alarm function, thereby ensuring that the nitrogen pressure is at a normal level during the filling process, eliminating the residual oxygen deviation in each liquid medicine bottle, and improving the quality of the liquid medicine.

[0026] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. A filling nitrogen filling system, comprising a front nitrogen filling station and a rear nitrogen filling station, wherein a digital electric contact pressure gauge is arranged on the main pipeline before the nitrogen enters the front and rear nitrogen filling stations, for real-time monitoring of the total nitrogen pressure on the front and rear nitrogen filling stations; a first flow meter, a first pneumatic diaphragm valve, a first solenoid valve and a first pressure transmitter are arranged at the front nitrogen filling station, and a second flow meter, a second pneumatic diaphragm valve, a second solenoid valve and a second pressure transmitter are arranged at the rear nitrogen filling station, and the nitrogen pressure on the pipelines of the front and rear nitrogen filling stations can be adjusted respectively by adjusting the nitrogen flow rates of the first and second flow meters; the switch states of the first and second pneumatic diaphragm valves are controlled by the first solenoid valve and the second solenoid valve respectively; The digital electric contact pressure gauge is provided with a third pressure alarm value, and when it is detected that the nitrogen pressure is lower than the third pressure alarm value, the filling nitrogen filling system alarms; in, The first pressure transmitter is located behind the first pneumatic diaphragm valve at the front nitrogen filling station, and the second pressure transmitter is located before the second pneumatic diaphragm valve at the rear nitrogen filling station.

2. In the filling nitrogen filling system as described in claim 1, the first pressure transmitter is provided with a first pressure alarm value, and the second pressure transmitter is provided with a second pressure alarm value. When the filling nitrogen pressure detected by the first pressure transmitter or the second pressure transmitter is lower than the corresponding pressure alarm value, the filling nitrogen filling system alarms.

3. A filling and nitrogen charging system as described in claim 1, wherein the second pneumatic diaphragm valve at the post-nitrogen charging station includes a pointer for indicating whether the second pneumatic diaphragm valve is open.

4. A filling and nitrogen charging system as described in claim 3, wherein a photoelectric sensor is provided at the post-nitrogen charging station to detect the pointer position of the second pneumatic diaphragm valve and confirm whether the second pneumatic diaphragm valve is open.

5. A filling machine, comprising a filling and nitrogen filling system as claimed in any one of claims 1 to 4, when the filling and nitrogen filling system alarms because the digital electric contact pressure gauge, the first pressure transmitter or the second pressure transmitter detects that the pressure is lower than its corresponding pressure alarm value, the filling machine alarms and stops the bottle feeding auger.

Citation Information

Patent Citations

  • Self-adaptive control system for performing air conveying on fragile materials

    CN108338404A

  • Ampoule filling machine with alarm device

    CN202322315U

  • Fill nitrogen controlling means

    CN206872408U

  • Gas boiler safety protection system

    CN208124264U

  • Filling and inflating device

    CN209618854U