A device for fully automatic determination of photon number by enzymatic chemiluminescence

Abstract

The present invention discloses a device for fully automatic determination of photon number by enzymatic chemiluminescence, including a cleaning structure and a detection mechanism, wherein the cleaning structure includes a driving motor, a transmission belt, a water inlet pipe, a water outlet pipe, a water pipe rack, a water inlet pump, a suction water pump, a first bottom plate, a reset chamber, a proximity sensor, a clamping block, a lifting platform, and a first electric motor. The invention is provided with a driving motor, a transmission belt, a water pipe rack, a suction water pump, a water inlet pump, a reset chamber, and a proximity sensor, so that the driving motor drives the transmission belt for transmission, so that the lifting platform and the water pipe rack move together, and the suction nozzle needle and the nozzle needle at the bottom of the clamping block are conveniently moved to the reset chamber, and liquid is injected and washed in the reset chamber by lifting and lowering, and the suction nozzle and the nozzle nozzle are checked to see whether they are normal, and the suction water pump and the water inlet pump are convenient to achieve the effect of pumping and filling water, and the proximity sensor is convenient to detect the position of the turntable.

Description

Technical Field

[0001] The invention relates to the field of chemiluminescence immunotechnology, and in particular to a device for fully automatic determination of photon number by enzymatic chemiluminescence. Background Art

[0002] Chemiluminescent immunoassay is a detection and analysis technology that combines highly sensitive chemiluminescent measurement technology with highly specific immune reactions. It is used for the detection and analysis of various antigens, haptens, antibodies, hormones, enzymes, fatty acids, vitamins and drugs. The current detection and cleaning equipment cannot achieve multi-position cleaning during operation, and cannot synchronize the cleaning and measurement of photon numbers during continuous detection. In addition, traditional cleaning and detection equipment has a simple structure and relatively traditional single function when in use, and cannot achieve the function of resetting the detection cleaning head to see if it is operating normally. Summary of the invention

[0003] The main purpose of the present invention is to provide a device for fully automatic determination of photon number by enzymatic chemiluminescence, which can effectively solve the problems in the background technology.

[0004] To achieve the above object, the technical solution adopted by the present invention is:

[0005] A device for fully automatic determination of photon number by enzymatic chemiluminescence, comprising a cleaning structure and a detection mechanism, wherein the cleaning structure comprises a driving motor, a transmission belt, a water inlet pipe, a water outlet pipe, a water pipe rack, a water inlet pump, a suction water pump, a first bottom plate, a reset chamber, a proximity sensor, a clamping block, a lifting platform, a first electric motor, a first screw, a nozzle needle, a nozzle needle and a track, wherein the detection mechanism comprises a second bottom plate, a second electric motor, a fixing plate, a transmission rod, a servo motor, an electric shifting block, a slide groove, a detection block and a second screw, wherein the first bottom plate is connected to the second bottom plate through a clamping groove, one end of the surface of the first bottom plate is fixedly connected to the suction water pump through a screw, the other end of the surface of the first bottom plate is fixedly connected to the proximity sensor, one side of the first bottom plate is fixedly connected to the track, one end of the track is provided with a reset chamber, one end of the middle part of the first bottom plate is fixedly connected to the driving motor through a mounting plate, one end of the driving motor is transmission-connected to the transmission belt, one side of the transmission belt is fixedly connected to the water pipe rack, and one end of the water pipe rack is fixed at the top A water inlet pump is connected, the water pipe rack is slidably connected to the track, the other side end of the transmission belt is fixedly connected to a lifting platform, one end of the lifting platform is fixedly connected to a first electric motor by a screw, the top end of the first electric motor is transmission-connected to a first screw, the first electric motor is transmission-connected to the lifting platform through the first screw, the other end of the lifting platform is clamped with a clamping block through a magnet, one end of the bottom end of the clamping block is clamped with a nozzle needle, the other end of the bottom end of the clamping block is clamped with a nozzle needle, the nozzle needle and the nozzle needle are respectively connected to the water inlet pump and the suction water pump through a water outlet pipe and a water inlet pipe, one end of the second bottom plate is fixedly connected to a second electric motor by a screw, the top end of the second electric motor is transmission-connected to a second screw, one end of the second bottom plate is fixedly connected to a detection block, one end of the second bottom plate is fixedly connected to a fixing plate by a screw, a sliding groove is opened on one side of the fixing plate, one end of the fixing plate is fixedly connected to a servo motor by a screw, and one end of the servo motor is transmission-connected to an electric shifting block through a transmission rod.

[0006] Furthermore, the length of the suction nozzle needle is greater than that of the nozzle needle, the suction nozzle needle and the nozzle needle correspond to the position of the reset chamber, and the suction nozzle needle and the nozzle needle are both detachable structures.

[0007] Furthermore, threads are arranged on the surfaces of the first screw and the second screw, and a limit block is arranged on the top end of the first screw.

[0008] Furthermore, the clamping block is a detachable structure, and a magnet at one end of the clamping block is clamped into one side of the inner part of the lifting platform.

[0009] Furthermore, an angle is set between the fixing plate and the track, and a gap is set between the fixing plate and the transmission rod.

[0010] Furthermore, an electric telescopic rod is provided in the middle of the electric shift block, and the electric shift block is clearance-matched with the slide groove.

[0011] Furthermore, a detachable partition is provided at the bottom of the detection block, and a gap is provided at the connection between the detection block and one end of the fixed plate.

[0012] Compared with the prior art, the present invention has the following beneficial effects:

[0013] (1): This invention is provided with a clamping block, a lifting platform, a first electric motor, a first screw, a suction nozzle needle and a nozzle needle, so that the first motor drives the first screw to rotate, so that the lifting platform can achieve an upward or downward movement, and the clamping block moves together, so that it is convenient to first suck liquid from the inside of the reagent card strip through the suction nozzle nozzle as the lifting platform descends, and then rises to inject liquid into the reagent through the nozzle needle, and the cleaning effect is achieved repeatedly;

[0014] (2): This invention is provided with a driving motor, a transmission belt, a water pipe rack, a suction water pump, a water inlet pump, a reset chamber and a proximity sensor, so that the driving motor drives the transmission belt to transmit the power, so that the lifting platform and the water pipe rack move together, and the suction nozzle needle and the nozzle needle at the bottom of the clamping block are moved to the reset chamber, and the suction nozzle and the nozzle nozzle are lifted and lowered to inject and absorb liquid in the reset chamber, and check whether the suction nozzle and the nozzle are normal. The suction water pump and the water inlet pump are used to facilitate the effect of pumping and filling water, and the proximity sensor is used to facilitate the detection of the position of the turntable;

[0015] (3): This invention is provided with a servo motor, a transmission rod, a fixed plate, a slide groove, a detection block, a second electric motor and a second screw rod, so that the servo motor can drive the transmission rod to rotate, so that the electric shift block moves to one end, and the electric shift block is lifted and lowered under the action of the electric telescopic rod. After being lowered, the shift block drives the reagent card strip to move toward the detection block. After being pushed into the detection block, the second electric motor drives the second screw rod to drive, so that the detector inside the detection block is lifted and lowered to detect the reagent card strip. After the detection is completed, the partition at the bottom of the detection block is used to facilitate the reagent card strip to fall. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 It is a schematic diagram of the overall structure of the present invention from a top view.

[0017] Figure 2 It is a schematic diagram of the overall top view of the cleaning mechanism of the present invention.

[0018] Figure 3 It is a schematic diagram of the overall top view of the detection mechanism of the present invention.

[0019] Figure 4It is a schematic diagram of the overall structure of the clamping block of the present invention.

[0020] In the figure: 1. driving motor; 2. transmission belt; 3. water inlet pipe; 4. water outlet pipe; 5. water pipe rack; 6. water inlet pump; 7. suction pump; 8. first bottom plate; 9. reset chamber; 10. proximity sensor; 11. clamping block; 12. lifting platform; 13. first electric motor; 14. first screw; 15. nozzle needle; 16. nozzle needle; 17. second bottom plate; 18. second electric motor; 19. fixing plate; 20. transmission rod; 21. servo motor; 22. electric shift block; 23. slideway; 24. detection block; 25. second screw; 26. track; 27. clamping groove; 28. detection mechanism; 29. ​​cleaning structure. DETAILED DESCRIPTION

[0021] In order to make the technical means, creative features, objectives and effects achieved by the present invention easy to understand, the present invention is further described below in conjunction with specific implementation methods.

[0022] like Figure 1-4As shown, a device for fully automatic determination of photon number by enzymatic chemiluminescence includes a cleaning structure 29 and a detection mechanism 28, wherein the cleaning structure 29 includes a driving motor 1, a transmission belt 2, a water inlet pipe 3, a water outlet pipe 4, a water pipe rack 5, a water inlet pump 6, a suction water pump 7, a first bottom plate 8, a reset chamber 9, a proximity sensor 10, a clamping block 11, a lifting platform 12, a first electric motor 13, a first screw 14, a nozzle needle 15, a nozzle needle 16 and a track 26, and the detection mechanism 28 includes a second bottom plate 17, a second electric motor 18, a fixing plate 19, a transmission rod 20, a servo motor 21, an electric shift block 22, a slide groove 23, detection block 24 and second screw 25, the first bottom plate 8 is clamped with the second bottom plate 17 through the clamping groove 27, one end of the surface of the first bottom plate 8 is fixedly connected to the suction pump 7 through screws, the other end of the surface of the first bottom plate 8 is fixedly connected to the proximity sensor 10, one side of the first bottom plate 8 is fixedly connected to the track 26, one end of the track 26 is provided with a reset chamber 9, one end of the middle part of the first bottom plate 8 is fixedly connected to the drive motor 1 through the mounting plate, one end of the drive motor 1 is transmission-connected to the drive belt 2, one side of the drive belt 2 is fixedly connected to the water pipe rack 5, one end of the water pipe rack 5 The top is fixedly connected with a water inlet pump 6, the water pipe rack 5 is slidably connected with the track 26, the other end of the transmission belt 2 is fixedly connected with a lifting platform 12, one end of the lifting platform 12 is fixedly connected with a first electric motor 13 by a screw, the top of the first electric motor 13 is transmission-connected with a first screw 14, the first electric motor 13 is transmission-connected with the lifting platform 12 through the first screw 14, the other end of the lifting platform 12 is clamped with a clamping block 11 through a magnet, one end of the bottom end of the clamping block 11 is clamped with a nozzle needle 15, the other end of the bottom end of the clamping block 11 is clamped with a nozzle needle 16, the nozzle needle 1 5 and the nozzle needle 16 are connected to the water inlet pump 6 and the suction water pump 7 through the water outlet pipe 4 and the water inlet pipe 3 respectively, one end of the second bottom plate 17 is fixedly connected to the second electric motor 18 by screws, the top of the second electric motor 18 is transmission-connected to the second screw rod 25, one end of the second bottom plate 17 is fixedly connected to the detection block 24, one end of the second bottom plate 17 is fixedly connected to the fixing plate 19 by screws, one side of the fixing plate 19 is provided with a slide groove 23, one end of the fixing plate 19 is fixedly connected to the servo motor 21 by screws, and one end of the servo motor 21 is transmission-connected to the electric shift block 22 through a transmission rod 20.

[0023] Among them, the length of the suction nozzle needle 15 is greater than the length of the nozzle needle 16, the suction nozzle needle 15 and the nozzle needle 16 correspond to the position of the reset chamber 9, and the suction nozzle needle 15 and the nozzle needle 16 are both detachable structures. The suction nozzle needle 15 and the nozzle needle 16 can be used to detect whether the injection and suction of liquid are normal at the reset chamber 9 position.

[0024] The surfaces of the first screw rod 14 and the second screw rod 25 are provided with threads, and a limit block is provided at the top end of the first screw rod 14 .

[0025] The clamping block 11 is a detachable structure, and a magnet at one end of the clamping block 11 is clamped into one side of the inner part of the lifting platform 12 .

[0026] There is an angle between the fixing plate 19 and the track 26 , and there is a gap between the fixing plate 19 and the transmission rod 20 .

[0027] An electric telescopic rod is disposed in the middle of the electric shift block 22 , and the electric shift block 22 is clearance-matched with the slide slot 23 .

[0028] A detachable partition is provided at the bottom of the detection block 24 , and a gap is provided at the connection between the detection block 24 and one end of the fixing plate 19 .

[0029] It should be noted that the present invention is a device for fully automatic determination of photon number by enzymatic chemiluminescence. During use, first, the driving motor 1 drives the water pipe rack 5 and the lifting platform 12 to drive together through the transmission belt 2, so that the lifting platform 12 drives the clamping block 11 and the first electric motor 13 to move. When the clamping block 11 moves to the top of the reset chamber 9, the first electric motor 13 drives the first screw 14 to rotate, so that the lifting platform 12 is lifted and lowered, thereby facilitating the nozzle needle 15 and the nozzle needle 16 to contact with the water inside the reset chamber 9. After the nozzle needle 15 and the nozzle needle 16 start working, the nozzle needle 15 and the nozzle needle 16 are detected. When cleaning is required, the driving motor 1 drives the transmission belt 2 to rotate, so that the lifting platform 12 is reset, and the first electric motor 13 drives the first screw 14 to rotate, so that the clamping block 11 is lifted and lowered. When the nozzle needle 15 at the bottom of the clamping block 11 contacts with the reagent card strip, under the action of the suction water pump 7 Under the action of the first electric motor 13, the nozzle needle 15 is raised, and the reagent card strip is rinsed by the nozzle needle 16 under the action of the water inlet pump 6. After the rinsing is completed, the nozzle needle 15 is lowered to suck again, and this is repeated to complete the cleaning effect. The position of the turntable can be effectively checked through the proximity sensor 10. Through the rotation of the turntable, the reagent card strip after cleaning reaches the detection mechanism 28, and the transmission rod 20 is driven to rotate by the servo motor 21. Then, under the telescopic action of the electric telescopic rod in the middle of the electric shift block 22, the electric shift block 22 is telescopically lowered, so that the electric shift block 22 is convenient to shift the reagent card strip to the detection block 24, and the second electric motor 18 drives the second screw rod 25 to achieve lifting and lowering, so that the detector inside the detection block 24 detects the reagent card strip. After the detection is completed, the partition facilitates the drop of the detected reagent card strip.

[0030] The above shows and describes the basic principles and main features of the present invention and the advantages of the present invention. It should be understood by those skilled in the art that the present invention is not limited to the above embodiments. The above embodiments and descriptions are only for explaining the principles of the present invention. Without departing from the spirit and scope of the present invention, the present invention may have various changes and improvements, which fall within the scope of the present invention to be protected. The scope of protection of the present invention is defined by the attached claims and their equivalents.

Claims

1. A device for fully automatic determination of photon number by enzymatic chemiluminescence, comprising a cleaning structure (29) and a detection mechanism (28), characterized in that: The cleaning structure (29) comprises a driving motor (1), a transmission belt (2), a water inlet pipe (3), a water outlet pipe (4), a water pipe rack (5), a water inlet pump (6), a suction pump (7), a first bottom plate (8), a reset chamber (9), a proximity sensor (10), a clamping block (11), a lifting platform (12), a first electric motor (13), a first screw rod (14), a nozzle needle (15), a nozzle needle (16) and a track (26); the detection mechanism (28) comprises a second bottom plate (17), a second electric motor (18), a fixing plate (19), a transmission rod (20), a servo motor (21), an electric shifting block (22), a slide groove (23), a detection block (24) and a second screw rod (25); The first bottom plate (8) is clamped with the second bottom plate (17) via a clamping groove (27); one end of the surface of the first bottom plate (8) is fixedly connected to a suction pump (7) via screws; the other end of the surface of the first bottom plate (8) is fixedly connected to a proximity sensor (10); one side of the first bottom plate (8) is fixedly connected to a track (26); a reset chamber (9) is provided at one end of one side of the track (26); one end of the middle of the first bottom plate (8) is fixedly connected to a drive motor (1) via a mounting plate; one end of the drive motor (1) is transmission-connected to a drive belt (2); one side of the drive belt (2) is fixedly connected to a water pipe rack (5); and one end of the water pipe rack (5) is fixedly connected to a water inlet pump (6). The water pipe rack (5) is slidably connected to the track (26); the other end of the transmission belt (2) is fixedly connected to a lifting platform (12); one end of the lifting platform (12) is fixedly connected to a first electric motor (13) by means of screws; the top end of the first electric motor (13) is transmission-connected to a first screw rod (14); the first electric motor (13) is transmission-connected to the lifting platform (12) by means of the first screw rod (14); the other end of the lifting platform (12) is clamped to a clamping block (11) by means of a magnet; one end of the bottom end of the clamping block (11) is clamped to a nozzle needle (15); the other end of the bottom end of the clamping block (11) is clamped to a nozzle needle (16); the nozzle needle (15) and the nozzle needle (16) are clamped to each other. 6) are connected to the water inlet pump (6) and the suction water pump (7) respectively through the water outlet pipe (4) and the water inlet pipe (3); one end of the second bottom plate (17) is fixedly connected to the second electric motor (18) by screws; the top end of the second electric motor (18) is transmission-connected to the second screw rod (25); one end of the second bottom plate (17) is fixedly connected to the detection block (24); one end of the second bottom plate (17) is fixedly connected to the fixing plate (19) by screws; a sliding groove (23) is provided on one side of the fixing plate (19); one end of the fixing plate (19) is fixedly connected to the servo motor (21) by screws; one end of the servo motor (21) is transmission-connected to the electric shifting block (22) by a transmission rod (20); The length of the suction nozzle needle (15) is greater than the length of the nozzle needle (16); the suction nozzle needle (15) and the nozzle needle (16) correspond to the positions of the reset chamber (9); and the suction nozzle needle (15) and the nozzle needle (16) are detachable structures; The surfaces of the first screw rod (14) and the second screw rod (25) are provided with threads, and a limit block is provided at the top end of the first screw rod (14); The clamping block (11) is a detachable structure, and a magnet at one end of the clamping block (11) is clamped into an inner side of the lifting platform (12); An angle is provided between the fixing plate (19) and the track (26), and a gap is provided between the fixing plate (19) and the transmission rod (20); A clamping block (11), a lifting platform (12), a first electric motor (13), a first screw (14), a nozzle needle (15) and a nozzle needle (16) are provided, so that the first electric motor (13) can drive the first screw (14) to rotate, thereby enabling the lifting platform (12) to rise or fall, and the clamping block (11) moves therewith, so that the nozzle needle (15) can firstly be used to suck liquid from the inside of the reagent card strip as the lifting platform (12) descends, and then the nozzle needle (16) is used to rise to inject liquid into the reagent.

2. The device for fully automatic determination of photon number by enzymatic chemiluminescence according to claim 1, characterized in that: An electric telescopic rod is provided in the middle of the electric shift block (22), and the electric shift block (22) is clearance-matched with the slide groove (23).

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