Disinfection device for coronavirus on surfaces that induces denaturation of the spike protein S

Abstract

The present invention discloses a method for disinfecting the surface of an object against coronavirus by inducing denaturation of the spike protein S. The method involves passing an object through an electric field formed by a negative electrode and a positive electrode at a constant speed and distance. The negative electrode of the electric field polarizes and detaches the coronavirus spike protein S1, which has a surface with positive electrostatic potential energy. Polarization and detachment of the coronavirus spike protein S1, which has a surface with positive electrostatic potential energy, irreversibly denatures the spike protein S. Also disclosed is a device for disinfecting the surface of an object against coronavirus by inducing denaturation of the spike protein S. After an object is conveyed along a conveyor line and aligned by a propulsion device, a first disinfection zone at the top of the conveyor line disinfects the front, back, and top of the object. A second disinfection zone disinfects the left and right sides of the object. Finally, a third disinfection zone disinfects the bottom of the object, thereby achieving the purpose of eliminating the virus.

Description

Technical Field

[0001] The present invention relates to the technical field of coronavirus disinfection, and in particular to a device for disinfecting coronavirus on the surface of an object by inducing denaturation of spike protein S. Background Art

[0002] Currently, chemical disinfection technologies for coronaviruses do not clearly define specific targets for coronavirus particles, nor do they provide detailed descriptions of the disinfection mechanisms of the disinfectants used, making it impossible to obtain effective guidance for coronavirus disinfection. Furthermore, the significant contamination of chemical disinfectants limits their scope of use. Furthermore, chemical disinfection devices require a specific operating environment. Open chemical disinfection methods generally employ spraying or wiping, and most water-based disinfectants only retain moisture on surfaces for 1-4 minutes, resulting in a relatively short action time. These methods lack the efficient, rapid, chemical-free, and widely applicable coronavirus disinfection capabilities proposed in the present invention.

[0003] The Chinese utility model patent with publication number CN211724143U discloses an air sterilization and disinfection system, including a clean room, which is equipped with an air intake area, a multi-stage air purification area and an exhaust area. The air intake area and the exhaust area are respectively located at both ends of the clean room. The air intake area includes an air guide port and a turbine fan. A multi-stage air purification area is provided between the air intake area and the exhaust area. The multi-stage air purification area includes at least a first-level physical filtration area and a first-level electric field adsorption purification area. The physical filtration area is located upstream of the electric field adsorption purification area. The air sterilization and disinfection system is equipped with a multi-stage air purification area in the clean room. It uses a combination of ultraviolet sterilization and high-voltage electrostatic sterilization to effectively remove viruses, bacteria and other microorganisms in the air and improve the air purification effect. It can also be used in the form of a vehicle-mounted tank, which is convenient for driving to epidemic areas and carrying out large-scale air sterilization and disinfection to disinfect infectious viruses such as the new coronavirus. The air sterilization and disinfection system is suitable for disinfecting bacteria in the air, but no disclosure is found on the principle of disinfecting coronaviruses on the surface of objects.

[0004] Chinese invention patent publication number CN111940143A discloses a sterilization, disinfection, and ozone removal electrostatic adsorption electrode and its preparation method. The electrode comprises an electrostatic dust collection electrode and a discharge electrode, the two electrodes being used in conjunction. The electrostatic dust collection electrode comprises an electrostatic dust removal electrode plate, the surface of which is coated with metal particles, forming a sterilization and disinfection metal particle coating on the surface of the electrostatic dust removal electrode plate; and the discharge electrode comprises a discharge electrode plate, the surface of which is coated with an ozone decomposition catalyst, forming an ozone decomposition catalyst coating on the surface of the discharge electrode plate. The electrode of the invention can continuously, efficiently, and thoroughly disinfect a broad spectrum of bacteria, viruses, and other microorganisms in the air under human conditions, and has important applications in the treatment of the new coronavirus. The sterilization, disinfection, and ozone removal adsorption electrode proposed in this invention can continuously, efficiently, and thoroughly disinfect harmful microorganisms in the air under human conditions, but does not have the function of disinfecting coronaviruses on the surface of objects. Summary of the Invention

[0005] The main purpose of the present invention is to overcome the shortcomings of the above-mentioned technology and provide a device for killing coronaviruses on the surface of objects by inducing denaturation of the spike protein S, which has the function of disinfecting coronaviruses on the surface of objects and expands the scope of application of electric field coronavirus disinfecting technology.

[0006] In order to overcome the above technical problems, the technical solution adopted by the present invention is:

[0007] A method for disinfecting the surface of an object from coronavirus by inducing denaturation of the spike protein S, characterized in that the disinfection method comprises the following steps:

[0008] Step 1: Pass the object through the electric field formed by the negative electrode and the positive electrode at a constant speed and distance;

[0009] Step 2: Using the negative pole of the electric field to polarize and remove the S1 of the coronavirus spike protein S with positive electrostatic potential energy on the surface of the object;

[0010] Step three, using the positive electrode of the electric field to polarize and fold the S2 with negative electrostatic potential energy surface of the coronavirus spike protein S on the surface of the object, causing the coronavirus spike protein S to undergo irreversible denaturation to achieve the disinfection of the coronavirus.

[0011] A coronavirus disinfection device for inducing denaturation of spike protein S on the surface of an object, characterized in that after the object is conveyed by a conveyor line and corrected by a propulsion device, the front, back, and top of the object are disinfected in a first disinfection zone arranged at the upper part of the conveyor line, and then the object is conveyed by the conveyor line to a second disinfection zone to disinfect the left and right sides of the object, and then the object is conveyed by the conveyor line to a third disinfection zone to disinfect the bottom of the object;

[0012] The conveyor line includes a frame body, a third disinfection zone arranged at the rear end connection of the frame body, a conveyor belt device respectively arranged in the upper end plane of the frame body, a second disinfection zone arranged on the frame body, and a propulsion device arranged on the frame body;

[0013] The frame body includes a frame body for arranging the conveyor line therein, a small frame body arranged at the rear end of the frame body and arranging the third disinfection zone therein, legs respectively arranged at the lower end surfaces of the front and rear ends of the frame body and used for supporting the ground, a first workbench arranged behind the legs at the front end of the frame body and connected to the lower end surface of the frame body, a second workbench connected to the lower end surface of the frame body and arranged behind the first workbench, a gantry frame arranged at the upper end surface of the frame body and corresponding to the position of the second workbench, a first fixing frame close to the front end of the frame body and arranged at the left end of the upper plane of the frame body, and a second fixing frame close to the front end of the frame body and arranged at the right end of the upper plane of the frame body and corresponding to the position of the first fixing frame;

[0014] The first workbench is used to set an electrical control box for controlling the operation of the conveying line, the propulsion device, the first disinfection zone, the second disinfection zone and the third disinfection zone;

[0015] The gantry frame and the second workbench are used to install the first disinfection area;

[0016] The first and second fixing brackets 23 are used to install the propulsion device;

[0017] Compared with the prior art, the beneficial effects of the present invention are: it has the function of disinfecting coronavirus on the surface of objects, and expands the scope of application of electric field coronavirus disinfection technology.

[0018] The technology proposed in the present invention for the electric field-induced denaturation of the coronavirus spike protein S to kill coronaviruses is suitable for the disinfection of coronaviruses on the surface of objects. It has the characteristics of simple structure, easy operation, fast disinfection speed, low disinfection cost, obvious disinfection effect, and no environmental pollution. It can be widely used for the disinfection of coronaviruses on the surface of objects in aviation, railways, roads, shipping, and water transport logistics, and plays a positive role in preventing the spread of coronaviruses through the surface of objects. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] The present invention will be further described in detail below with reference to the accompanying drawings and specific embodiments.

[0020] Figure 1 is an isometric view of the present invention.

[0021] Figure 2 yes Figure 1 Shown is a partial enlarged view of area B.

[0022] Figure 3It is an isometric view of the frame body of the present invention.

[0023] Figure 4 is an isometric view of the present invention.

[0024] Figure 5 yes Figure 4 Shown is a partial enlarged view of area A.

[0025] Figure 6 yes Figure 1 The above is a partial enlarged view of the C area.

[0026] Figure 7 yes Figure 1 Shown is a partial enlarged view of area D.

[0027] Figure 8 yes Figure 4 Shown is a partial enlarged view of area E.

[0028] Figure 9 It is the front view of the present invention.

[0029] Figure 10 yes Figure 9 Shown is a partial enlarged view of area F.

[0030] Figure 11 This is the connection schematic diagram of the programmable controller. DETAILED DESCRIPTION

[0031] A method for disinfecting the surface of an object from coronavirus by inducing denaturation of the spike protein S, comprising the following steps:

[0032] Step 1: Pass the object through the electric field formed by the negative electrode and the positive electrode at a constant speed and distance;

[0033] Step 2: Using the negative pole of the electric field to polarize and remove the S1 of the coronavirus spike protein S with positive electrostatic potential energy on the surface of the object;

[0034] Step three, using the positive electrode of the electric field to polarize and fold the S2 with negative electrostatic potential energy surface of the coronavirus spike protein S on the surface of the object, causing the coronavirus spike protein S to undergo irreversible denaturation to achieve the disinfection of the coronavirus.

[0035] like Figure 1-11As shown, a coronavirus disinfection device for inducing denaturation of spike protein S on the surface of an article, after the article is conveyed by the conveyor line 12 and corrected by the propulsion device 3, the front, back and top of the article are disinfected by the first disinfection zone 13 set on the upper part of the conveyor line 12, and then the article is conveyed by the conveyor line 12 to the second disinfection zone 14 to disinfect the left and right sides of the article, and then the article is conveyed by the conveyor line 12 to the third disinfection zone 15 to disinfect the bottom of the article;

[0036] The conveyor line 12 includes a frame body 1, a third disinfection zone 15 provided at the rear end connection of the frame body 1, a conveyor belt device 2 provided in the upper end plane of the frame body 1, a second disinfection zone 14 provided on the frame body 1, and a propulsion device 3 provided on the frame body 1;

[0037] The conveyor belt device 2 is driven by a speed-regulating motor 2-1 disposed at the front end of the frame body 1. A small sprocket is mounted on the shaft extension of the speed-regulating motor 2-1. The small sprocket is connected to a large pulley on the main shaft of the conveyor belt device 2 via a chain. One end of the belt is disposed on the main shaft, and the other end of the belt is disposed on the passive shaft of the frame body 1. A belt tensioner assembly is disposed between the main shaft and the passive shaft, a belt sliding support is disposed between the main shaft and the belt tensioner assembly, and a belt sliding support is disposed between the belt tensioner assembly and the passive shaft. The speed-regulating motor drives the small sprocket, which in turn transmits the large sprocket via the chain. The large sprocket drives the main shaft to rotate, which in turn drives the belt to rotate, thereby moving items placed on the belt forward.

[0038] The frame body 1 includes a frame body 16 for arranging the conveyor line 12 therein, a small frame body 17 arranged at the rear end of the frame body 16 and arranging the third disinfection area 15 therein, legs 18 respectively arranged at the lower end surfaces of the front and rear ends of the frame body 16 and used for supporting the ground, a first workbench 19 arranged behind the legs 18 at the front end of the frame body 16 and connected to the lower end surface of the frame body 16, a second workbench 20 connected to the lower end surface of the frame body 16 and arranged behind the first workbench 19, a gantry frame 21 arranged on the upper end surface of the frame body 16 and corresponding to the position of the second workbench 20, a first fixing frame 22 close to the front end of the frame body 1 and provided at the left end of the upper plane of the frame body 1, and a second fixing frame 23 close to the front end of the frame body 1 and provided at the right end of the upper plane of the frame body 1 and corresponding to the position of the first fixing frame 22;

[0039] The first workbench 19 is used to set the electrical control box 10 for controlling the operation of the conveyor line 12, the propulsion device 3, the first disinfection zone 13, the second disinfection zone 14 and the third disinfection zone 15;

[0040] The gantry frame 21 and the second workbench 20 are used to install the first disinfection area 13;

[0041] The first fixing frame 22 and the second fixing frame 23 are used to install the propulsion device 3;

[0042] Furthermore, the propulsion device 3 includes an actuator 24 fixedly connected to the first fixed frame 22, a push plate 25 threadedly connected to the protruding end of the actuator 24, and two ranging sensors 26 arranged on the second fixed frame 23; wherein the two ranging sensors 26 are arranged up and down on the first vertical pole 23-1 of the second fixed frame 23.

[0043] Preferably, the distance sensor 26 is of model FLR-10-RS485, with a distance range of 15-100 mm. It is connected to the programmable controller 10 - 1 via the RS485 communication protocol, and provides feedback of distance parameters between the programmable controller 10 - 1 and the distance sensor 26 .

[0044] Preferably, the actuator 24 is a linear motor for ease of on-site power connection. Depending on the needs of the customer's site, the actuator 24 may also be a hydraulic cylinder or a pneumatic cylinder. The front end of the hydraulic cylinder or pneumatic cylinder body is connected to the first fixing bracket 22, and the end of the piston rod of the hydraulic cylinder or pneumatic cylinder body is threadedly connected to the push plate 25.

[0045] Preferably, the linear motor used as actuator 24 is model RKD40-400-11-DX-40-B3, secured to the upper cross arm of first mounting bracket 22 with fasteners. The front end of the linear motor's push rod is threadedly connected to a square plate having uniformly spaced holes. These holes are connected to fasteners that connect the square plate to push plate 25.

[0046] Furthermore, the first disinfection area 13 includes a horizontal moving device 4 arranged on the top of the gantry frame 21 and parallel to the conveying direction of the conveyor line 12, a vertical moving device 5 connected to the horizontal moving device 4 and perpendicular to the conveying direction of the conveyor line 12, a positive electrostatic generator 8 and a negative electrostatic generator 9 arranged on the second workbench 20, and a distance measuring sensor 26 respectively arranged on the front beam 27 and the second column 28 of the gantry frame 21, and a scanner 7 connected to the vertical moving device 5;

[0047] 150kV-resistant wires connect the terminals of the positive and negative electrostatic generators 8 and 9 to the terminals of the electrode assembly 6. The electrode assembly 6 described herein consists entirely of an insulating plate 6-1, a negative electrode 6-2, and a positive electrode 6-3. The negative electrode 6-2 is located in front of the insulating plate 6-1, and the positive electrode 6-2 is located behind the insulating plate 6-1. This allows the electrode assembly 6 to simultaneously generate both a negative and a positive electric field. Objects passing through the conveyor line 12 first pass through the negative field and then the positive field, scanning the object surface through alternating electric fields. The negative and positive electrodes 6-2 and 6-3 of the electrode assembly 6 are each 3mm wide.

[0048] The coronavirus spike protein S1 is polarized in the electrostatic field to produce stretching and contraction oscillations, causing it to denature at a lower electrostatic field intensity, leading to structural changes in the coronavirus spike protein S1 and irreversible denaturation to achieve the purpose of disinfecting the virus.

[0049] The horizontal moving device 4 includes a linear module 29 arranged on the top of the gantry frame 21 and parallel to the conveying direction of the conveyor line 12, and a first slide 30 connected to a slide groove 31 on one side of the linear module 29 and used to connect to the vertical moving device 5;

[0050] The vertical moving device 5 includes a linear module 29 connected to the first slide 30 and perpendicular to the conveying direction of the conveyor line 12, a second slide 33 connected to a slide groove 31 on one side of the linear module 29, and a scanner 7 connected to the second slide 33;

[0051] The scanner 7 includes a support rod 34 connected to the fixing plate of the second slide 33 at one end, a scanning frame 35 connected to the support rod 34, and electrode devices 6 respectively arranged at the front end, rear end and lower end of the scanning frame 35;

[0052] The electrode device 6 includes an insulating plate 6-1, a negative electrode 6-2, and a positive electrode 6-3, wherein the insulating plates 6-1 are respectively installed at the front end, rear end, and lower end of the scanning frame 35. The negative electrodes 6-2 are respectively arranged above the insulating plates 6-1 at the front end and rear end of the scanning frame 35, and the positive electrodes 6-3 are respectively arranged below the insulating plates 6-1 at the front end and rear end of the scanning frame 35; the negative electrodes 6-2 are respectively arranged in front of the insulating plates 6-1 at the lower end of the scanning frame 35, and the positive electrodes 6-3 are respectively arranged behind the insulating plates 6-1 at the lower end of the scanning frame 35;

[0053] Furthermore, the width of the scanning frame 35 is equal to the width of the conveyor line 12 to ensure that all objects on the conveyor line 12 can be scanned by the electrode device 6 provided on the scanning frame 35 .

[0054] Furthermore, the third disinfection zone 15 arranged inside the small frame 17 is the electrode device 6, wherein the insulating plate 6-1 of the electrode device 6 is arranged in the middle of the small frame 17, the negative electrode 6-2 of the electrode device 6 is arranged at the front end of the insulating plate 6-1, and the positive electrode 6-3 of the electrode device 6 is arranged at the rear end of the insulating plate 6-1.

[0055] Furthermore, the second disinfection zone 14 includes two electrode shells 37, the openings of which are all facing the conveyor line 12, wherein one electrode shell 37 is connected to the front end vertical rod 36 at the rear of the frame body 1, and also includes a horizontal moving component 38, the fixed end of the horizontal moving component 38 is connected to the rear end vertical rod 36 at the rear of the frame body 1, so that the protruding end of the horizontal moving component 38 is connected to the back of the other electrode shell 37; the insulating plates 6-1 of the electrode device 6 are respectively installed inside the electrode shell 37, and the negative electrodes 6-2 of the electrode device 6 are respectively set at the front ends of the insulating plates 6-1 of the electrode shell 37, and the positive electrodes 6-3 of the electrode device 6 are respectively set at the rear ends of the insulating plates 6-1 of the electrode shell 37.

[0056] Preferably, the horizontal moving component 38 is a linear motor.

[0057] Furthermore, the opening of one electrode shell 37 is aligned with the opening of the other electrode shell 37 .

[0058] Furthermore, the electrical control box 10 is provided with a programmable controller 10-1 and a control panel 10-2, and the output end of the programmable controller 10-1 is respectively connected to the positive electrostatic generator 8, the negative electrostatic generator 9, the propulsion device 3, the first disinfection zone 13, the second disinfection zone 14, the third disinfection zone 15, and the conveyor belt device 2;

[0059] The input end of the programmable controller 10-1 is respectively connected to the two distance measuring sensors 26 on the second fixing frame 23, the distance measuring sensor 26 on the front beam 27, and the distance measuring sensor 26 on the second column 28.

[0060] The output ends of the positive electrostatic generator 8 are connected to the first disinfection zone 13, the second disinfection zone 14, and the third disinfection zone 15 respectively;

[0061] The output ends of the negative electrostatic generator 9 are connected to the first disinfection zone 13, the second disinfection zone 14, and the third disinfection zone 15 respectively;

[0062] The control panel 10-2 is provided with a main switch 39, a knob 40 for controlling the speed of the conveyor belt device 2, a first switch 41 for controlling the positive electrostatic generator 8, and a second switch 42 for controlling the negative electrostatic generator 9. The knob 40 controls the speed controller in the conveyor belt device 2. Preferably, the speed controller is model 120W-1220-2. The preferred models of the first switch 41, the main switch 39, and the second switch 42 are KCD4.

[0063] When in use, turn on the main switch 39 on the control panel 10-2, the equipment starts, the programmable controller 10-1 controls the propulsion device 3, the first disinfection zone 13, and the second disinfection zone 14 to reset, the conveyor line 12, the positive electrostatic generator 8, and the negative electrostatic generator 9 are powered on, and the items pass through the ranging sensor 26 on the second fixed frame 23, and the ranging signal is transmitted to the programmable controller 10-1. The programmable controller 10-1 adjusts and controls the propulsion device 3, the first disinfection zone 13, and the third disinfection zone 15 according to the distance signal.

[0064] Example 1

[0065] refer to Figure 1 It can be seen that when the shape of the disinfected item is a cuboid or a cube, the disinfected item first passes through the correction area. After the item is conveyed by the conveyor line 12 and corrected by the propulsion device 3, the front, back and top of the item are disinfected by the first disinfection area 13 set on the upper part of the conveyor line 12. Then, the item is conveyed by the conveyor line 12 to the second disinfection area 14 to disinfect the left and right sides of the item, and then conveyed by the conveyor line 12 to the third disinfection area 15 to disinfect the bottom of the item.

[0066] After starting the disinfection device, the conveying speed of the conveyor line 12 is set to 4.2m / min, and the items run on the conveyor line 12 at a speed of 4.2m / min. The items first pass through the two distance sensors 26 set on the second fixed frame 23. The distance sensor 26 arranged below the bottom of the first vertical pole 23-1 on the second fixed frame 23 controls the stroke of the actuator 24, so that the push plate 25 always maintains a distance value of 15mm between the items to be disinfected and the two distance sensors 26 on the second fixed frame 23. While completing the correction of the items, they continue to be conveyed forward through the conveyor line 12. The distance sensor 26 arranged above the bottom of the first vertical pole 23-1 is used to detect the front of the item. After the front of the item is detected, the back of the item is detected during the conveying process.

[0067] When the article is continuously conveyed forward, the article passes through the distance measuring sensor 26 on the front beam 27 of the gantry frame 21. The distance measuring sensor 26 on the front beam 27 detects the height of the article on the conveyor line 12. The height value is the distance measured by the distance measuring sensor 26 on the front beam 27 plus 15 mm from the zero position of the electrode device 6 at the front end of the scanner 7 scanning frame 35. The height value is fed back to the programmable controller 10-1. The programmable controller 10-1 converts the calculated height value of the article into an electrical signal and sends it to the vertical moving device 5, the positive electrostatic generator 8 and the negative electrostatic generator 9 respectively to make them work. The positive electrostatic generator 8 and the negative electrostatic generator After operation, the front electrode device 6 in the scanner 7 will operate and form a negative electric field and a positive electric field. By moving the vertical moving device 5, and during movement, the front electrode device 6 in the scanner 7 completes the scanning and disinfection of the front of the object at a distance of 15 mm from the front of the object. Then, the negative pole of the electric field formed by the electrode device 6 at the front end of the scanning frame 35 is used to polarize the S1 of the coronavirus spike protein S with a positive electrostatic potential energy surface on the front surface of the object and cause it to fall off; the positive pole of the electric field formed by the electrode device 6 at the front end of the scanning frame 35 is used to polarize the S2 of the coronavirus spike protein S with a negative electrostatic potential energy surface on the front surface of the object and cause it to fold, causing the spike protein S to undergo irreversible denaturation.

[0068] Then, the distance values ​​of the front and back of the detected object are fed back to the programmable controller 10-1 through the distance measuring sensor 26 arranged above the bottom of the first vertical pole 23-1. The distance measured by the distance measuring sensor 26 above the bottom of the first vertical pole 23-1 is the distance from the front of the object to the electrode device 6 at the lower end of the scanning frame 35 of the scanner 7 at the zero position plus 15 mm. The programmable controller 10-1 calculates the distance values ​​in front of and behind the object and converts the converted electrical signals into electrical signals, which are respectively sent to the horizontal moving device 4, the positive electrostatic generator 8 and the negative electrostatic generator 9 to make them work. After the positive electrostatic generator 8 and the negative electrostatic generator 9 work, the lower electrode device 6 in the scanner 7 will run and form a negative electromagnetic field and a positive electromagnetic field. Through the movement of the horizontal moving device 4, and when moving, the lower electrode device 6 in the scanner 7 completes the scanning and disinfection of the object at a distance of 15 mm from the top of the object. Then, the negative pole of the electric field formed by the electrode device 6 at the lower end of the scanning frame 35 is used to polarize and fall off the S1 of the coronavirus spike protein S on the surface of the object with a positive electrostatic potential energy surface; the positive pole of the electric field formed by the electrode device 6 at the front end of the scanning frame 35 is used to polarize and fold the S2 of the coronavirus spike protein S on the upper surface of the object with a negative electrostatic potential energy surface, causing the spike protein S to undergo irreversible denaturation.

[0069] The moving distance value of the horizontal moving device 4 is the distance value between the front and back of the object detected by the distance measuring sensor 26 above the bottom of the first vertical pole 23-1. The horizontal moving device 4 is controlled by the programmable controller 10-1.

[0070] When the horizontal moving device 4 is in operation, the first slide 30 of the horizontal moving device 4 drives the vertical moving device 5 to move horizontally, so that the scanner 7 connected to the vertical moving device 5 installed on the horizontal moving device 4 is close to the rectangular or cube-shaped object, and the front end of the object is consistent with the conveying direction of the conveyor line 12;

[0071] When scanning the back of an object, the distance values ​​between the front and back of the detected object are fed back to the programmable controller 10-1 through the distance measuring sensor 26 arranged above the bottom of the first vertical pole 23-1. The distance from the back of the object measured by the distance measuring sensor 26 above the bottom of the first vertical pole 23-1 is the distance from the back of the object to the electrode device 6 at the rear end of the scanning frame 35 of the scanner 7 at the zero position plus 15 mm. The programmable controller 10-1 calculates the distance values ​​in front and behind the object and converts the converted electrical signals into electrical signals, which are respectively sent to the horizontal moving device 4, the positive electrostatic generator 8 and the negative electrostatic generator 9 to make them work. After the positive electrostatic generator 8 and the negative electrostatic generator 9 work, the rear end electrode device 6 in the scanner 7 will run and form a negative electric field and a positive electric field. Through the up and down movement of the vertical moving device 5, and when moving, the rear end electrode device 6 in the scanner 7 completes the scanning and disinfection of the back of the object at a distance of 15 mm from the back of the object. Then, the negative pole of the electric field formed by the electrode device 6 at the rear end of the scanning frame 35 is used to polarize and fall off the S1 of the coronavirus spike protein S on the surface of the object with a positive electrostatic potential energy surface; the positive pole of the electric field formed by the electrode device 6 at the front end of the scanning frame 35 is used to polarize and fold the S2 of the coronavirus spike protein S on the upper surface of the object with a negative electrostatic potential energy surface, causing the spike protein S to undergo irreversible denaturation.

[0072] Subsequently, the article is transported out of the first disinfection zone 13 by the conveyor line. After the article completely passes the distance sensor 26 on the second column 28, the distance sensor 26 on the second column 28 feeds back the distance values ​​of the front and back of the article to the programmable controller 10-1. The programmable controller 10-1 calculates the distance values ​​of the front and back of the article and converts the converted electrical signals into the electrode device 6 in the third disinfection zone 15, the two electrode devices 6 set in the second disinfection zone 14, the positive electrostatic generator 8 and the negative electrostatic generator 9 and makes them work respectively. After the positive electrostatic generator 8 and the negative electrostatic generator 9 work, the two electrode devices 6 set in the second disinfection zone 14 will run and form a negative electric field and a positive electric field, and move the article through the conveyor line 12. When moving, the front of the article first passes through the electric field formed by the two electrode devices 6 set in the second disinfection zone 14. The negative electric field of the field is passed through the positive electric field formed by the two electrode devices 6 arranged in the second disinfection zone 14, and then the left and right sides of the article pass through the negative electric field and the positive electric field formed by the two electrode devices 6 arranged in the second disinfection zone 14 respectively. Finally, the back of the article passes through the negative electric field and the positive electric field formed by the two electrode devices 6 arranged in the second disinfection zone 14. That is to say, after the left and right sides of the article are scanned and disinfected by the negative electric field and the positive electric field formed by the two electrode devices 6 arranged in the second disinfection zone 14, the front and back of the article are scanned again in succession, so that the front and back are more thoroughly disinfected, which plays a double insurance role. Because when the article is moved out of the conveyor line, people are accustomed to holding the front and back of the article with their left and right hands. Therefore, the safety of people when carrying articles is effectively guaranteed, so that people are not infected by potential coronaviruses on the front and back surfaces of the articles.

[0073] When the items are transported, the distance sensor 26 arranged at the bottom of the first vertical pole 23-1 is used to control the stroke of the actuator 24, so that the push plate 25 always maintains a distance of 15mm between the items to be disinfected and the two distance sensors 26 on the second fixed frame 23. When the first disinfection zone scans the front, top, and back of the items, they are all scanned at a constant distance of 15mm. Therefore, the items are not touched by any parts. Therefore, when the left and right sides of the items pass through the two electrode devices 6 of the second disinfection zone, the front and back end surfaces of the items are also kept at 15mm from the corresponding electrode devices 6 of the second disinfection zone 14 to complete the scanning and disinfection. Furthermore, the negative pole of the electric field formed by the two electrode devices 6 in the second disinfection zone is used to polarize and detach the S1 with positive electrostatic potential energy surface of the coronavirus spike protein S on the left and right surfaces of the items.

[0074] The positive pole of the electric field formed by the two electrode devices 6 in the second disinfection zone is used to polarize and fold the S2 with negative electrostatic potential energy surface of the coronavirus spike protein S on the left and right surfaces of the object, causing the spike protein S to undergo irreversible denaturation.

[0075] The bottom surface of the article is scanned and disinfected through the third disinfection zone 15. The top of the electrode device 6 in the small frame 17 is 15 mm lower than the top of the conveyor line 12. Therefore, after the article is disinfected on both sides, the bottom surface of the article is transported by the conveyor line 12 and scanned by the negative electric field and the positive electric field formed by the electrode device 6 in the small frame 17 to complete the disinfection. Then, the negative pole of the electric field formed by the electrode device 6 in the third disinfection zone is used to polarize and fall off the S1 of the coronavirus spike protein S with a positive electrostatic potential energy surface on the bottom surface of the article; the positive pole of the electric field formed by the electrode device 6 in the third disinfection zone is used to polarize and fold the S2 of the coronavirus spike protein S with a negative electrostatic potential energy surface on the bottom surface of the article, causing the spike protein S to undergo irreversible denaturation. In summary, all six surfaces of the article are disinfected.

[0076] Electrode assembly 6 performs disinfection in the following manner: the electrode potential of electrode assembly 6 in first disinfection zone 13, second disinfection zone 14, and third disinfection zone 15 is 5 kV to 60 kV. The distance between electrode assembly 6 and the surface of the object is adjustable within a range of 1.25 mm to 250 mm, and is controlled by programmable controller 10-1 based on the voltage level. This distance range is a parameter for disinfection and does not change randomly during the disinfection process.

[0077] The effective range of electric field strength is 3×10 5 -4×10 6 V / m, the minimum residence time of the article in the electrode device 6 is 0.04 seconds, the widths of the negative electrode 6-2 and the positive electrode 6-3 are 3 mm respectively, and the conveying line speed is 4.2 m / min.

[0078] The electrode device 6 uses an electrostatic potential double electrode with a negative electrode 6-3 and a positive electrode 6-3. When an object passes through the electrode device 6, it sequentially enters the negative electric field generated by the negative electrode 6-3 in the electrode device 6 and the positive electric field generated by the positive electrode 6-2 in the electrode device 6;

[0079] In the negative electric field area, the positive electrostatic potential energy surface of the coronavirus spike protein S1 is polarized and detached by the negative electrode. After S1 is detached, the negative electrostatic potential energy surface of the virus S2 is subsequently polarized by the positive electrode to fold and denature, thereby achieving the purpose of disinfecting the coronavirus. The electrodes of the device use a double electrode with positive and negative electrostatic potential, that is, the positive electrode 6-3 is in front and the negative electrode 6-3 is in the back. This can also complete the disinfecting of the coronavirus, but the effect is not as good as the double electrode with negative and positive electrostatic potential.

[0080] Each electrode device 6 is equipped with a negative electrode 6-2 and a positive electrode 6-3. Because of the high voltage, an insulating plate 6-1 is required between the negative electrode 6-2 and the positive electrode 6-3. When disinfecting, each side of the object passes through the negative electrode first and then the positive electrode to increase the disinfection effect.

[0081] Example 2

[0082] The electrode device 6 adopts an alternating electric field mode. When working, the alternating electric field mode can form an alternating electric field as the electrode device 6 is added; for example, in the small frame 17 inside the third disinfection zone 15, more than two electrode devices 6 are set, so as to form a positive and negative electric field alternation mode. For another example, the second disinfection zone 14 is provided with more than two groups of vertical poles 36 on the frame body 1, and each vertical pole 36 is provided with an electrode shell 37. The openings between each electrode shell 37 are all set toward the conveyor line 12, and the electrode devices 6 are respectively installed inside the electrode shell 37, and the electrode devices 6 are respectively installed inside the electrode shell 37. The insulating plate 6-1 of the electrode shell 37 is provided with a negative electrode 6-2 of the electrode device 6 at the front end, and a positive electrode 6-3 of the electrode device 6 at the rear end of the insulating plate 6-1 of the electrode shell 37. In this way, when working, a negative and positive electric field alternation is formed. The positive and negative electric field waveforms formed by the electrode device 6 are square waves, triangle waves, and sine waves. The frequency range is 1K-3KHz, and the electrode potential is 2KV-100KV. The coronavirus spike protein S1 stretches and oscillates in the alternating electric field, causing it to denature at a lower electric field strength, thereby achieving the purpose of disinfecting the virus. Increasing the number of electrodes in each group can ensure that the coronavirus increases the speed of movement of items under the premise of meeting the minimum residence time in the electrode area, thereby achieving the purpose of improving the disinfecting efficiency.

[0083] Example 3

[0084] Experimental part

[0085] 1. Virus toxicity (TCID50) determination:

[0086] A common method for measuring viral toxicity is the TCID50 (50% tissue culture infection dose, TCID50). The TCID50 represents the amount of virus that causes cytopathic effects in 50% of the inoculated cells. It is the virus dilution that causes cytopathic effects in half of the cell monolayer tubes (wells). This method only estimates the strength and quantity of viral infectivity and cannot accurately determine the number of infectious virus particles.

[0087] Karber method formula: lgTCID50=L+d(S-0.5)

[0088] Where: L- minimum dilution factor of virus

[0089] d-dilution coefficient, i.e. group distance

[0090] Sum of S-cell lesion ratios (excluding the lowest dilution lesion ratio)

[0091] For example: Table 1

[0092] Table 1 is the virus TCID50 determination table

[0093]

[0094] =-2

[0095] D=-1

[0096] S=4 / 4+4 / 4+3 / 4+2 / 4+0 / 4=4.25

[0097] lgTCID50=L+d(S-0.5)=-2+(-1)(4.25-0.5)=-5.75

[0098] TCID50 = 10-5.75 = 1 / 560000

[0099] If the dilution is 0.1 ml, then 1 ml contains 5,600,000 TCID50. The virus titer is usually expressed as the number of TCID50 per ml.

[0100] Experimental results:

[0101] The object moves through the second disinfection zone at a speed of 4.2 m / min, and the electrode voltage intensity is 4×10 3 V, virus titer (lgTCID50) with changing the distance between the electrode device and the surface of the object (r, mm);

[0102] Measurement results: When the electrode potential is fixed, r is inversely proportional to the electric field strength. During disinfection, it was found that the virulence (1g TCID50) of the virus does not respond linearly to the electric field; there is a window of time during which the disinfection effect is optimal. The experimental data are shown in Table 2.

[0103] Table 2 Relationship between the distance R between the electrode device and the surface of the object and the virus titer (1g TCID50)

[0104]

[0105] During disinfection, it was found that the virulence of the virus (lgTCID50) did not respond linearly to the electric field, and there was a window (the electric field strength was 2.7×10 4 V / m, under experimental conditions the distance between the electrode and the surface of the object is 15 mm), and the disinfection effect is best in this window.

[0106] The object moves through the second disinfection zone at a speed of V (m / min), and the electrode voltage intensity is 4×10 3 V, virus titer (1g TCID50) at the distance between the electrode device and the surface of the object (15 mm);

[0107] Measurement results: Under constant electric field strength conditions, the speed of the object is inversely proportional to the disinfection time. Experimental values ​​indicate that slower speeds result in longer disinfection times and better results. However, due to the short disinfection time required, disinfection effectiveness deteriorates significantly after a speed of 4.5 m / min. To balance disinfection effectiveness and efficiency, a speed of 4.2 m / min is considered feasible. The experimental data is shown in Table 3.

[0108] Table 3

[0109]

[0110]

[0111] The present invention is not limited to the exact construction that has been described above and shown in the drawings, and various modifications and changes may be made without departing from its scope. The scope of the present invention is limited only by the appended claims.

Claims

1. A coronavirus disinfection device for the surface of an object that induces denaturation of the spike protein S, characterized in that: After the article is conveyed by the conveyor line (12) and corrected by the propulsion device (3), the front, back and top of the article are disinfected by the first disinfection zone (13) arranged on the upper part of the conveyor line (12), and then the article is conveyed by the conveyor line (12) to the second disinfection zone (14) to disinfect the left and right sides of the article, and then the article is conveyed by the conveyor line (12) to the third disinfection zone (15) to disinfect the bottom of the article; The first disinfection zone (13) comprises a horizontal moving device (4) arranged on the top of the gantry frame (21) and parallel to the conveying direction of the conveyor line (12), a vertical moving device (5) connected to the horizontal moving device (4) and perpendicular to the conveying direction of the conveyor line (12), a positive electrostatic generator (8) and a negative electrostatic generator (9) arranged on the second workbench (20), and a distance measuring sensor (26) respectively arranged on the front beam (27) and the second column (28) of the gantry frame (21), and a scanner (7) connected to the vertical moving device (5); The horizontal moving device (4) includes a linear module (29) arranged on the top of the gantry frame (21) and parallel to the conveying direction of the conveying line (12), and a first slide (30) connected to a slide groove (31) on one side of the linear module (29) and used to connect to the vertical moving device (5); The vertical moving device (5) includes a linear module (29) connected to the first slide (30) and perpendicular to the conveying direction of the conveying line (12), a second slide (33) connected to a slide groove (31) on one side of the linear module (29), and a scanner (7) connected to the second slide (33); The scanner (7) includes a support rod (34) connected to a fixing plate of the second slide (33) at one end, a scanning frame (35) connected to the support rod (34), and electrode devices (6) respectively arranged at the front end, the rear end and the lower end of the scanning frame (35); The electrode device (6) includes an insulating plate (6-1), a negative electrode (6-2), and a positive electrode (6-3), wherein the insulating plate (6-1) is respectively installed at the front end, the rear end and the lower end of the scanning frame (35), and the negative electrode (6-2) is respectively arranged above the insulating plate (6-1) located at the front end and the rear end of the scanning frame (35), and the positive electrode (6-3) is respectively arranged below the insulating plate (6-1) located at the front end and the rear end of the scanning frame (35); the negative electrode (6-2) is respectively arranged in front of the insulating plate (6-1) located at the lower end of the scanning frame (35), and the positive electrode (6-3) is respectively arranged behind the insulating plate (6-1) located at the lower end of the scanning frame (35).

2. A coronavirus disinfection device for inducing denaturation of spike protein S on the surface of an object according to claim 1, characterized in that: The width of the scanning frame (35) is equal to the width of the conveying line (12).

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