Switchable liquid inlet system, method, liquid path system and analysis device
By designing a switchable liquid inlet system, and automatically switching the cleaning liquid storage components using the control unit and switching components, the problem of the inability to automate the liquid inlet system in the prior art is solved, and the automatic operation of the liquid inlet system and the improvement of the user experience is achieved.
Patent Information
- Application Number
- CN202111094616.6
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2021-09-17
- Publication Date
- 2025-02-07
- Estimated Expiration
- 2041-09-17
AI Technical Summary
The existing cleaning liquid inlet system cannot meet users' needs for automation of the liquid inlet system, and users need to pay frequent attention to and replace the cleaning liquid to maintain the normal operation of the instrument.
A switchable liquid inlet system is designed, including a control unit, a switching assembly, a cleaning liquid storage assembly and a detection assembly. The control unit generates a switching signal to switch the switching component to another cleaning liquid storage component based on the alarm signal sent by the detection component or the cleaning liquid storage component.
Automatic switching of the liquid inlet system is realized, reducing the frequent monitoring and replacement of cleaning liquid storage by users, and ensuring the continuous and uninterrupted operation of the instrument.
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Figure CN113702657B_ABST
Abstract
Description
Technical Field
[0001] The present invention relates to the field of automation technology, and in particular to a switchable liquid inlet system, method, liquid path system and analysis device. Background Art
[0002] The existing cleaning liquid inlet system is limited by the size of the instrument and the capacity of the cleaning liquid barrel. Users are often required to frequently pay attention to the cleaning liquid reserves in the inlet system and replace the cleaning liquid in time to maintain the normal and uninterrupted operation of the instrument. It cannot meet the user's demand for the automation of the inlet system. Summary of the invention
[0003] The embodiments of the present invention provide a switchable liquid inlet system, method, liquid circuit system and analysis device, aiming to solve the problem that the inherent control of the liquid inlet system in the prior art cannot meet the automation requirements of users.
[0004] In a first aspect, an embodiment of the present invention provides a switchable liquid inlet system, comprising a control unit, a switching component, at least two cleaning liquid storage components for storing cleaning liquid, and a detection component for monitoring the storage amount of cleaning liquid in the currently connected cleaning liquid storage components, one end of the switching component is connected to the pipelines of at least two cleaning liquid storage components, the other end of the switching component is connected to the liquid outlet channel pipeline, the control unit is connected to the switching component and the detection component by signal, wherein:
[0005] The control unit is used to generate a switching signal and send it to the switching component when receiving an alarm signal sent by the detection component, so that the switching component switches from the currently connected cleaning liquid storage component to another cleaning liquid storage component; or, the control unit is used to determine whether the cleaning liquid storage amount in the cleaning liquid storage component is lower than the storage amount alarm threshold according to the cleaning liquid storage amount signal when receiving a cleaning liquid storage amount signal sent by the detection component; if so, the control unit sends an alarm signal associated with the detection component, and generates a switching signal and sends it to the switching component, so that the switching component switches from the currently connected cleaning liquid storage component to another cleaning liquid storage component.
[0006] In a second aspect, an embodiment of the present invention provides a switchable liquid inlet method, which includes:
[0007] The control unit is used to generate a switching signal and send it to the switching component when receiving the alarm signal sent by the detection component, so that the switching component switches from the currently connected cleaning liquid storage component to another cleaning liquid storage component;
[0008] Alternatively, the control unit is used to determine whether the cleaning fluid storage amount in the cleaning fluid storage component is lower than the storage amount alarm threshold value based on the cleaning fluid storage amount signal when receiving the cleaning fluid storage amount signal sent by the detection component; if so, the control unit sends an alarm signal associated with the detection component, and generates a switching signal and sends it to the switching component, so that the switching component switches from the currently connected cleaning fluid storage component to another cleaning fluid storage component.
[0009] In a third aspect, an embodiment of the present invention provides a liquid circuit system of a luminescent immunoassay analyzer, comprising: a sample reagent quantitative module for quantitatively filling a sample reagent, a sample reagent cleaning and waste discharge module, a cleaning plate cleaning module, a waste liquid waste discharge module for discharging waste liquid, a switchable liquid inlet module for providing a cleaning liquid, and a waste liquid recovery module for recovering waste liquid;
[0010] The sample reagent cleaning and waste discharge module is respectively connected to the switchable liquid inlet module and the sample reagent quantitative module, and is used to extract cleaning liquid from the switchable liquid inlet module and clean the sample reagent quantitative module;
[0011] The cleaning tray cleaning module is connected to the switchable liquid inlet module and is used to extract cleaning liquid from the switchable liquid inlet module and clean the cleaning tray;
[0012] The waste liquid recovery module is connected to the sample reagent cleaning and waste discharge module and the waste liquid discharge module respectively, and is used to recover the cleaning waste liquid discharged from the sample reagent cleaning and waste discharge module, and to recover the cleaning waste liquid discharged from the waste liquid discharge module;
[0013] The switchable liquid inlet module executes any of the switchable liquid inlet methods described above.
[0014] In a fourth aspect, an embodiment of the present invention provides an analysis device, including a reagent sample needle module, a reagent disk module, an incubation photometry module, a magnetic separation module and a liquid inlet module, wherein:
[0015] The reagent sample needle module is used to absorb reagents and samples;
[0016] The reagent tray module is used to store reagents;
[0017] The incubation and photometry module is used to incubate the object to be tested and detect the object to be tested to obtain the test result;
[0018] The magnetic separation module is used to clean and separate the magnetic beads and unreacted waste liquid;
[0019] The liquid inlet module is used to execute any of the switchable liquid inlet methods described above.
[0020] The embodiment of the present invention provides a switchable liquid inlet system, method, liquid circuit system and analysis device. The system includes a control unit, a switching component, at least two cleaning liquid storage components for storing cleaning liquid, and a detection component for real-time monitoring of the storage amount of cleaning liquid in at least two of the cleaning liquid storage components. The liquid inlet end of the switching component is connected to the pipelines of at least two of the cleaning liquid storage components, and the liquid outlet end of the switching component is connected to the liquid outlet channel pipeline. The control unit is connected to the switching component and the detection component by signal, wherein the control unit is used to generate a switching signal and send it to the switching component when receiving an alarm signal sent by the detection component, so that the switching component switches from the currently connected cleaning liquid storage component to another cleaning liquid storage component. In this system, the control unit generates a switching signal based on the alarm signal of the detection component and sends it to the switching component, controls the switching component to switch the cleaning liquid storage component, meets the user's demand for automation of the liquid inlet system, and improves the user experience. BRIEF DESCRIPTION OF THE DRAWINGS
[0021] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the accompanying drawings required for use in the description of the embodiments will be briefly introduced below. Obviously, the accompanying drawings described below are some embodiments of the present invention. For ordinary technicians in this field, other accompanying drawings can be obtained based on these accompanying drawings without paying any creative work.
[0022] Figure 1 A schematic diagram of the structure of a switchable liquid inlet system provided in an embodiment of the present invention;
[0023] Figure 2 A schematic diagram of a sub-process of an embodiment of a switchable liquid inlet method provided in an embodiment of the present invention;
[0024] Figure 3 A schematic diagram of another sub-process of an embodiment of the switchable liquid inlet method provided in an embodiment of the present invention;
[0025] Figure 4 A schematic diagram of another sub-process of an embodiment of the switchable liquid inlet method provided in an embodiment of the present invention;
[0026] Figure 5 A schematic diagram of another sub-process of an embodiment of the switchable liquid inlet method provided in an embodiment of the present invention;
[0027] Figure 6 A schematic diagram of another sub-process of an embodiment of a switchable liquid inlet method provided in an embodiment of the present invention;
[0028] Figure 7 A schematic structural diagram of an embodiment of a switchable liquid inlet system provided in an embodiment of the present invention. DETAILED DESCRIPTION
[0029] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.
[0030] It should be understood that when used in this specification and the appended claims, the terms "include" and "comprises" indicate the presence of described features, integers, steps, operations, elements and / or components, but do not exclude the presence or addition of one or more other features, integers, steps, operations, elements, components and / or combinations thereof.
[0031] It should also be understood that the terms used in this specification of the present invention are only for the purpose of describing specific embodiments and are not intended to limit the present invention. As used in the specification of the present invention and the appended claims, unless the context clearly indicates otherwise, the singular forms "a", "an" and "the" are intended to include plural forms.
[0032] It should be further understood that the term "and / or" used in the present description and the appended claims refers to any and all possible combinations of one or more of the associated listed items, and includes these combinations.
[0033] See also Figure 1 As shown, Figure 1 A schematic diagram of the structure of a switchable liquid inlet system provided in an embodiment of the present invention, the system comprises a control unit, a switching component, at least two cleaning liquid storage components for storing cleaning liquid, and a detection component for real-time monitoring of the storage amount of cleaning liquid in at least two of the cleaning liquid storage components, the liquid inlet end of the switching component is connected to the pipeline of at least two of the cleaning liquid storage components, the liquid outlet end of the switching component is connected to the liquid outlet channel pipeline, the control unit is connected to the switching component and the detection component by signal, wherein:
[0034] The control unit is used to generate a switching signal and send it to the switching component when receiving the alarm signal sent by the detection component, so that the switching component switches from the currently connected cleaning liquid storage component to another cleaning liquid storage component;
[0035] Alternatively, the control unit is used to determine whether the cleaning fluid storage amount in the cleaning fluid storage component is lower than the storage amount alarm threshold value based on the cleaning fluid storage amount signal when receiving the cleaning fluid storage amount signal sent by the detection component; if so, the control unit sends an alarm signal associated with the detection component, and generates a switching signal and sends it to the switching component, so that the switching component switches from the currently connected cleaning fluid storage component to another cleaning fluid storage component.
[0036] In this embodiment, the control unit can be any processor capable of data processing, such as a microprocessor, a programmable controller, etc.; the switching component can be any switching switch, switching valve, etc. capable of pipeline switching; the cleaning liquid storage component can be any container capable of storing cleaning liquid, such as a barrel, a bottle, etc.; the detection component can be any detection device capable of monitoring the storage amount of cleaning liquid in the cleaning liquid storage component, such as a weight sensor, a water level sensor, etc., and when it is detected that the storage amount of cleaning liquid in the cleaning liquid storage component is insufficient and is lower than the storage amount alarm threshold, an alarm signal is sent to the control unit. When the control unit is in the on state, if the alarm signal sent by the detection component is received, a switching signal is generated and sent to the switching component; after receiving the switching signal, the switching component switches from the currently connected cleaning liquid storage component to another cleaning liquid storage component, so that the user does not need to plan the replacement time of the cleaning liquid storage component, and the liquid inlet system switches to another cleaning liquid storage component to ensure a continuous supply of cleaning liquid in the liquid inlet system, so that the liquid inlet system can continue to operate uninterruptedly.
[0037] For example, the current switching valve (i.e., the switching component) is connected to the cleaning liquid barrel T1 (i.e., the cleaning liquid storage component 1) and the cleaning liquid barrel T2 (i.e., the cleaning liquid storage component 2) storing the cleaning liquid, wherein the switching valve and the cleaning liquid barrel T1 are connected, and the switching valve and the cleaning liquid barrel T2 are disconnected. When the control unit receives the alarm signal sent by the detection component, the switching valve switches from the cleaning liquid barrel T1 to the cleaning liquid barrel T2.
[0038] In one embodiment, the control unit receives a cleaning fluid storage level signal sent by the detection component, and determines whether the cleaning fluid storage level in the cleaning fluid storage component is lower than the storage level alarm threshold based on the cleaning fluid storage level signal; if so, the control unit sends an alarm signal associated with the detection component, and generates a switching signal to send to the switching component, so that the switching component switches from the currently connected cleaning fluid storage component to another cleaning fluid storage component.
[0039] For example, the current switching valve (i.e., the switching component) is connected to the cleaning liquid barrel T1 (i.e., the cleaning liquid storage component 1) and the cleaning liquid barrel T2 (i.e., the cleaning liquid storage component 2) storing the cleaning liquid, wherein the switching valve and the cleaning liquid barrel T1 are connected, and the switching valve and the cleaning liquid barrel T2 are disconnected. The control unit receives the cleaning liquid storage amount signal sent by the detection component, and the control unit determines whether the cleaning liquid storage amount in the cleaning liquid barrel T1 is lower than the storage amount alarm threshold according to the cleaning liquid storage amount signal. If the cleaning liquid storage amount signal indicates that the cleaning liquid storage amount in the cleaning liquid barrel T1 is lower than the storage amount alarm threshold, the control unit generates a switching signal and sends it to the switching valve, so that the switching valve switches from the cleaning liquid barrel T1 to the cleaning liquid barrel T2.
[0040] In one embodiment, the switchable liquid inlet system provided by the embodiment of the present invention also includes a pipeline sensing component, which is arranged in the liquid outlet channel. The pipeline sensing component is connected to the control unit signal for real-time monitoring of the cleaning liquid outflow from the liquid outlet channel, and when the liquid outflow alarm threshold is reached, sending an alarm signal to the control unit; or, the pipeline sensing component is used to send a cleaning liquid outflow signal of the liquid outlet channel to the control unit, so that when the control unit receives the cleaning liquid outflow signal, it determines whether the cleaning liquid outflow from the liquid outlet channel is lower than the liquid outflow alarm threshold according to the cleaning liquid outflow signal, and if so, sends an alarm signal associated with the pipeline sensing component.
[0041] In this embodiment, in order to facilitate the detection of the outflow of cleaning liquid from the liquid outlet channel, a pipeline sensing component is provided in the liquid outlet channel, and the outflow of cleaning liquid from the liquid outlet channel is monitored by the pipeline sensing component. Among them, the pipeline sensing component can be a bubble sensing component or a water level sensing component, etc. The pipeline sensing component monitors the outflow of cleaning liquid from the liquid outlet channel in real time, and sends an alarm signal to the control unit when the outflow of cleaning liquid is lower than the outflow alarm threshold; or, the pipeline sensing component sends the outflow signal of cleaning liquid from the liquid outlet channel to the control unit; the control unit receives the outflow signal of cleaning liquid, and determines whether the outflow of cleaning liquid in the liquid outlet channel is lower than the outflow alarm threshold according to the outflow signal of cleaning liquid. When the outflow of cleaning liquid is lower than the outflow alarm threshold, the control unit sends an alarm signal associated with the pipeline sensing component.
[0042] For example, the pipeline sensing component is a bubble sensor, and when it is detected that the outflow of cleaning liquid in the liquid outlet channel is lower than the outflow alarm threshold, the bubble sensor sends an alarm signal to the control unit. Alternatively, the bubble sensor sends the outflow signal of cleaning liquid in the liquid outlet channel to the control unit, and the control unit receives the outflow signal of cleaning liquid and determines whether the outflow of cleaning liquid in the liquid outlet channel is lower than the outflow alarm threshold according to the outflow signal of cleaning liquid; when the outflow of cleaning liquid is lower than the outflow alarm threshold, the control unit sends an alarm signal associated with the bubble sensor.
[0043] In one embodiment, the switchable liquid inlet system provided by the embodiment of the present invention further includes a buffer component, which is connected to the liquid outlet channel pipeline and is used for buffering and storing the cleaning liquid output from the liquid outlet channel.
[0044] In this embodiment, in order to facilitate the user to store the cleaning liquid, a buffer component is provided in the liquid outlet channel for storing the cleaning liquid output from the liquid outlet channel, and the buffer component is connected to the liquid outlet channel pipeline to transport the cleaning liquid. The cleaning liquid flows from the liquid outlet pipe into the buffer component for storage. It should be noted that the buffer component can be any container, such as a barrel or a bottle. The cleaning liquid stored in the buffer component can be used by other systems or devices that require cleaning liquid.
[0045] In one embodiment, the detection component includes a first detection unit for monitoring the storage amount of the cleaning liquid in at least two of the cleaning liquid storage components and a second detection unit for monitoring the storage amount of the cleaning liquid in the buffer component, and the first detection unit and the second detection unit are both connected to the control unit signal.
[0046] In this embodiment, in order to better realize the switching, the detection component includes a first detection unit for monitoring the storage amount of the cleaning liquid in at least two cleaning liquid storage components, and a second detection unit for monitoring the storage amount of the cleaning liquid in the buffer component. Wherein, the first detection unit and the second detection unit are both connected to the control unit signal. The control unit switches the cleaning liquid storage component according to the alarm signal of the first detection unit; the control unit starts and closes the liquid inlet process according to the alarm signal of the second detection unit, thereby realizing the function of the switchable liquid inlet system. Wherein, the first detection unit can be the above-mentioned weight sensor, water level sensor, etc., and the second detection unit can be a float sensor, etc. Specifically, the float sensor has high and low positions, the circuit is disconnected when it is low, and the circuit is connected when it is high; when the float is low, it means that the storage amount of the cleaning liquid in the buffer component is insufficient, and at this time, a liquid inlet signal can be sent to the control unit, and when it is high, it means that the storage amount of the cleaning liquid in the buffer component is full, and at this time, an alarm signal can be sent to the control unit.
[0047] In one embodiment, a pump assembly is provided between the buffer assembly and the switching assembly, and the pump assembly is used to provide power for the liquid inlet system to transfer the cleaning liquid from the cleaning liquid storage assembly to the buffer assembly.
[0048] The present invention also provides a liquid filling method of a switchable liquid filling system as described in any one of the above, comprising: the control unit is used to generate a switching signal and send it to the switching component when receiving the alarm signal sent by the detection component, so that the switching component switches from the currently connected cleaning liquid storage component to another cleaning liquid storage component;
[0049] Alternatively, the control unit is used to determine whether the cleaning fluid storage amount in the cleaning fluid storage component is lower than the storage amount alarm threshold value based on the cleaning fluid storage amount signal when receiving the cleaning fluid storage amount signal sent by the detection component; if so, the control unit sends an alarm signal associated with the detection component, and generates a switching signal and sends it to the switching component, so that the switching component switches from the currently connected cleaning fluid storage component to another cleaning fluid storage component.
[0050] like Figure 2 As shown, in the switchable liquid inlet method provided by the present invention, when the control unit receives the alarm signal sent by the detection component, it generates a switching signal and sends it to the switching component, so that the switching component switches from the currently connected cleaning liquid storage component to another cleaning liquid storage component, including:
[0051] Step S101, during the liquid inlet process, when the control unit receives the alarm signal sent by the detection component, it determines whether the alarm signal sent by the pipeline sensing component is received;
[0052] Step S102: if the alarm signal sent by the detection component and the alarm signal sent by the pipeline sensing component are received at the same time, a switching signal is generated and sent to the switching component, so that the switching component switches from the currently connected cleaning liquid storage component to another cleaning liquid storage component;
[0053] Step S103: If the alarm signal sent by the pipeline sensor component is not received, a first fault signal is generated.
[0054] In this embodiment, during the liquid inlet process of the liquid inlet system, the control unit monitors the alarm signals of the detection component and the pipeline sensor component in real time. When receiving the alarm signal sent by the detection component, the control unit determines whether the alarm signal sent by the pipeline sensor component is received. If the alarm signals sent by the pipeline sensor component and the monitoring component are received at the same time, it proves that the cleaning liquid storage amount of the cleaning liquid storage component and the cleaning liquid flow rate in the liquid outlet channel pipeline have reached the alarm amount, and it is necessary to replace the current cleaning liquid storage component in time to restore the liquid outlet of the cleaning liquid. Therefore, the control unit generates a switching signal and sends it to the switching component, so that the switching component switches from the currently connected cleaning liquid storage component to another cleaning liquid storage component. If the alarm signal sent by the pipeline sensor component is not received, a first fault signal indicating that there is a damaged device component in the liquid inlet system is generated. Among them, the device component includes a detection component, a pipeline sensor component, a switching component or a pump liquid component.
[0055] like Figure 3As shown, in the switchable liquid inlet method provided by the present invention, when the control unit receives the alarm signal sent by the detection component, it generates a switching signal and sends it to the switching component, so that the switching component switches from the currently connected cleaning liquid storage component to another cleaning liquid storage component, including:
[0056] Step S201: During the liquid inlet process, when the control unit receives the alarm signal sent by the pipeline sensing component, it determines whether the alarm signal sent by the detection component is received;
[0057] Step S202: if the alarm signal sent by the detection component and the alarm signal sent by the pipeline sensing component are received at the same time, a switching signal is generated and sent to the switching component, so that the switching component switches from the currently connected cleaning liquid storage component to another cleaning liquid storage component;
[0058] Step S203: If the alarm signal sent by the detection component is not received, a second fault signal is generated.
[0059] In this embodiment, during the liquid inlet process, when the control unit receives the alarm signal sent by the pipeline sensing component, it determines whether the alarm signal sent by the detection component is received. If the alarm signal sent by the detection component is not received, it indicates that there is sufficient cleaning liquid in the cleaning liquid storage component, but the cleaning liquid flow in the liquid outlet channel is insufficient and is lower than the liquid outlet alarm threshold, then a second fault signal is generated indicating that there is a pipeline fault in the liquid inlet system. Among them, pipeline faults may include loose pipeline joints, squeezed pipelines and other possible faults. The present application is divided into a first fault signal and a second fault signal according to the cause of the fault, which can help users conduct targeted inspections when encountering faults and reduce system maintenance pressure.
[0060] For example, the detection component is a weight sensor, and the pipeline sensing component is a bubble sensor. If the alarm signal of the weight sensor and the alarm signal of the bubble sensor are currently received, the switching component switches from the cleaning liquid barrel T1 currently connected to the cleaning liquid barrel T2; if the alarm signal of the weight sensor is currently received but the alarm signal of the bubble sensor is not received, a first fault signal is generated; if the alarm signal of the bubble sensor is currently received but the alarm signal of the weight sensor is not received, a second fault signal is generated.
[0061] like Figure 4 As shown, in the switchable liquid inlet method provided by the present invention, when the control unit receives the alarm signal sent by the detection component, it generates a switching signal and sends it to the switching component, so that the switching component switches from the currently connected cleaning liquid storage component to another cleaning liquid storage component, including:
[0062] Step S301: during the liquid inlet process, when the control unit issues an alarm signal associated with the detection component, determining whether to issue an alarm signal associated with the pipeline sensing component;
[0063] Step S302: if the alarm signals associated with the detection component and the pipeline sensing component are simultaneously issued, a switching signal is generated and sent to the switching component, so that the switching component switches from the currently connected cleaning liquid storage component to another cleaning liquid storage component;
[0064] Step S303: If no alarm signal associated with the pipeline sensor assembly is issued, a first fault signal is generated.
[0065] In this embodiment, during the liquid inlet process, when the control unit sends out an alarm signal associated with the detection component, it is determined whether to send out an alarm signal associated with the pipeline sensing component; if the alarm signals associated with the detection component and the pipeline sensing component are sent out at the same time, it is proved that the cleaning liquid storage amount of the cleaning liquid storage component and the cleaning liquid flow rate in the liquid outlet channel pipeline have reached the alarm amount, and it is necessary to replace the current cleaning liquid storage component in time to restore the liquid outflow of the cleaning liquid, so the control unit generates a switching signal and sends it to the switching component to switch the switching component from the currently connected cleaning liquid storage component to another cleaning liquid storage component. If the alarm signal associated with the pipeline sensing component is not sent out, a first fault signal indicating that there is a damaged component in the liquid inlet system is generated. Among them, when the control unit sends out an alarm signal associated with the detection component, it indicates that the storage amount of the cleaning liquid in the cleaning liquid storage component is lower than the storage amount alarm threshold; when the control unit sends out an alarm signal associated with the pipeline sensing component, it indicates that the cleaning liquid outflow of the liquid outlet channel is lower than the liquid outflow alarm threshold.
[0066] like Figure 5 As shown, in the switchable liquid inlet method provided by the present invention, when the control unit receives the alarm signal sent by the detection component, it generates a switching signal and sends it to the switching component, so that the switching component switches from the currently connected cleaning liquid storage component to another cleaning liquid storage component, including:
[0067] Step S401: during the liquid inlet process, when the control unit issues an alarm signal associated with the pipeline sensing component, determining whether to issue an alarm signal associated with the detection component;
[0068] Step S402: if the alarm signals associated with the detection component and the pipeline sensing component are simultaneously issued, a switching signal is generated and sent to the switching component, so that the switching component switches from the currently connected cleaning liquid storage component to another cleaning liquid storage component;
[0069] Step S403: If no alarm signal associated with the detection component is issued, a second fault signal is generated.
[0070] In this embodiment, during the liquid inlet process, when the control unit sends out an alarm signal associated with the pipeline sensing component, it determines whether to send out an alarm signal associated with the detection component; if the alarm signal associated with the detection component is not sent out, it indicates that there is sufficient cleaning liquid in the cleaning liquid storage component, but the cleaning liquid flow in the liquid outlet channel is insufficient and is lower than the liquid outlet alarm threshold, then a second fault signal is generated indicating that there is a pipeline fault in the liquid inlet system.
[0071] For example, the detection component is a weight sensor, and the pipeline sensing component is a bubble sensor. If the current control unit sends out an alarm signal associated with the weight sensor and also sends out an alarm signal associated with the bubble sensor, the switching component switches from the currently associated cleaning fluid barrel T1 to the cleaning fluid barrel T2; if the current alarm signal associated with the weight sensor is sent out, and the alarm signal associated with the bubble sensor is not sent out, a first fault signal is generated; if the current alarm signal associated with the bubble sensor is sent out, and the alarm signal associated with the weight sensor is not sent out, a second fault signal is generated.
[0072] like Figure 7 The structure diagram of an embodiment of the switchable liquid inlet system provided by the present invention is shown. C1 and C2 are two weighing sensors (equivalent to the first detection unit), which are respectively placed under the bases corresponding to the placement positions of the cleaning liquid barrel T1 and the cleaning liquid barrel T2. Q is a bubble sensor (equivalent to the pipeline sensing component), SV1 is a switching valve (equivalent to the switching component), P is a liquid inlet pump (equivalent to the pump liquid component), and F is a float sensor (equivalent to the second detection unit), which is placed in a buffer barrel H (equivalent to the buffer component). The weighing sensors C1 and C2 can monitor the changes in the storage volume of the cleaning liquid in the two cleaning liquid barrels in real time, and a storage volume alarm threshold can be set. When the storage volume of the cleaning liquid is lower than the storage volume alarm threshold, an alarm signal is issued. The bubble sensor Q is installed on the liquid outlet channel pipeline, and the bubbles in the pipeline are detected by infrared rays. The liquid outlet alarm threshold can be set, and an alarm signal is issued when the liquid outlet volume of the cleaning liquid is lower than the liquid outlet alarm threshold. The bubble sensor Q is calibrated to make the alarm level of the weighing sensors C1 and C2 basically consistent. The switching valve SV1 switches from the currently connected cleaning liquid barrel T1 to the cleaning liquid barrel when receiving the switching signal; the liquid inlet pump P is used to transfer the cleaning liquid to the buffer barrel H.
[0073] During the operation of the liquid inlet system, in the initial state, the switching valve SV1 is connected to the cleaning liquid barrel T1. As the water level in the buffer barrel H drops, the circuit is disconnected when the float sensor F is at a low position, and the system generates a liquid inlet signal to start the liquid inlet process. The liquid inlet pump P starts working, and the weighing sensor C1, the weighing sensor C2 and the bubble sensor Q start monitoring synchronously. The following situations exist: (1) When neither the weighing sensor C1 nor the bubble sensor Q alarms, the liquid inlet pump P continues to work until the float sensor F sends an alarm signal and stops inletting. The float sensor F alarm indicates that the cleaning liquid in the buffer barrel H has reached a high level and the cleaning liquid storage in the buffer barrel H is full, completing the liquid inlet process. (2) When both the bubble sensor Q and the weighing sensor C1 send out alarm signals, it indicates that the storage volume of the cleaning liquid in the cleaning liquid barrel T1 and the discharge volume of the cleaning liquid in the liquid discharge channel are insufficient. The control unit generates a switching signal and sends it to the switching valve SV1, so that the switching valve SV1 disconnects the cleaning liquid barrel T1 and connects the cleaning liquid barrel T2. When the bubble sensor Q and the weighing sensor C2 are normal, the liquid inlet pump continues to work until the float sensor F sends out an alarm signal and stops working to complete the liquid inlet. When at least one of the bubble sensor Q and the weighing sensor C2 still sends out an alarm signal, the control unit generates a first fault signal or a second fault signal. (3) When only one of the weighing sensor C1 or C2 and the bubble sensor Q sends out an alarm signal, the control unit generates a first fault signal or a second fault signal.
[0074] It should be noted that, according to the alarm relationship between the weighing sensors C1, C2 and the bubble sensor Q, the faults can be divided into the following types: (1) When the bubble sensor Q alarms and the weighing sensor C1 or C2 alarms, it is most likely that the cleaning liquid storage volume in the cleaning liquid barrel T1 and the cleaning liquid barrel T2 is insufficient, and the cleaning liquid in the liquid outlet pipeline has also been exhausted, and the cleaning liquid barrel needs to be replaced as soon as possible; (2) When the bubble sensor Q alarms and the weighing sensor C1 or C2 does not alarm, it may be that the cleaning liquid is sufficient and the pipeline is empty. The control unit generates a second fault signal, allowing the user to focus on whether the pipeline joints are loose or whether the pipeline is squeezed; (3) When the bubble sensor Q does not alarm, but the weighing sensor C1 or C2 alarms, the control unit generates a first fault signal, prompting the user that there is a fault in the weighing sensor C1 or C2, the bubble sensor Q, the liquid inlet valve or the liquid inlet pump, or there is a deviation in the calibration of the component.
[0075] like Figure 6 As shown, in one embodiment, the liquid feeding method further includes:
[0076] Step S501, using the detection component to monitor in real time the storage amount of the cleaning liquid in at least two of the cleaning liquid storage components;
[0077] Step S502, counting the remaining amount information according to the detected storage amount of the cleaning liquid to obtain statistical data;
[0078] Step S503, rendering the statistical data to obtain rendering data;
[0079] Step S504: calling a preset display framework to perform a UI display on the rendering data.
[0080] In this embodiment, in order to facilitate the user to more intuitively know the cleaning liquid situation in the liquid inlet system, the detection component is used to monitor the storage volume of the cleaning liquid in at least two cleaning liquid storage components in real time; then the remaining information is counted according to the cleaning liquid storage volume to obtain statistical data; the statistical data is rendered using rendering processing to obtain rendering data; and the preset display framework is called to display the rendering data in the UI. Among them, the display framework can be adjusted according to actual needs, so that the display interface is detailed and clear, and the two sensors can effectively calculate the remaining volume, which is convenient for users to quickly know the current cleaning liquid situation and plan the replacement time of the cleaning liquid storage component as soon as possible.
[0081] The present invention also discloses a liquid circuit system of a luminescent immunoassay analyzer, the liquid circuit system comprising: a sample reagent quantitative module for quantitatively adding sample reagents, a sample reagent cleaning and waste discharge module, a cleaning plate cleaning module, a waste liquid waste discharge module for discharging waste liquid, a switchable liquid inlet module for providing cleaning liquid, and a waste liquid recovery module for waste liquid recovery; wherein:
[0082] The sample reagent cleaning and waste discharge module is respectively connected to the switchable liquid inlet module and the sample reagent quantitative module, and is used to extract cleaning liquid from the switchable liquid inlet module and clean the sample reagent quantitative module;
[0083] The cleaning tray cleaning module is connected to the switchable liquid inlet module and is used to extract cleaning liquid from the switchable liquid inlet module and clean the cleaning tray;
[0084] The waste liquid recovery module is connected to the sample reagent cleaning and waste discharge module and the waste liquid discharge module respectively, and is used to recover the cleaning waste liquid discharged from the sample reagent cleaning and waste discharge module, and to recover the cleaning waste liquid discharged from the waste liquid discharge module;
[0085] The switchable liquid inlet module performs the switchable liquid inlet method as described above.
[0086] The present invention also discloses an analysis device, which includes a reagent sample needle module, a reagent disk module, an incubation photometry module, a magnetic separation module and a liquid inlet module, wherein:
[0087] Reagent sample needle module, used for aspirating reagents and samples;
[0088] A reagent tray module, used for storing reagents;
[0089] An incubation and photometry module is used to incubate the object to be tested and detect the object to be tested to obtain the test result;
[0090] A magnetic separation module, used for cleaning and separating magnetic beads and unreacted waste liquid;
[0091] The liquid inlet module is used to execute the switchable liquid inlet method described above.
[0092] The system and method detect whether the storage amount of cleaning fluid in the cleaning fluid storage component is lower than the storage amount alarm threshold through the detection component. When the storage amount of cleaning fluid is lower than the storage amount alarm threshold, an alarm signal is generated and sent to the control unit. The control unit generates a switching signal and sends it to the switching component to control the switching component to switch the cleaning fluid storage component, so that the user does not need to frequently pay attention to the storage amount of cleaning fluid in the liquid inlet system. The liquid inlet system automatically switches the cleaning fluid storage component to maintain uninterrupted operation of the liquid inlet system, thereby improving the user experience.
[0093] Those skilled in the art can clearly understand that, for the convenience and simplicity of description, the specific working process of the above-described equipment, devices and units can refer to the corresponding process in the aforementioned method embodiment, and will not be repeated here. Those of ordinary skill in the art can appreciate that the units and algorithm steps of each example described in conjunction with the embodiments disclosed herein can be implemented with electronic hardware, computer software or a combination of the two. In order to clearly illustrate the interchangeability of hardware and software, the composition and steps of each example have been generally described in the above description according to the function. Whether these functions are executed in hardware or software depends on the specific application and design constraints of the technical solution. Professional and technical personnel can use different methods to implement the described functions for each specific application, but such implementation should not be considered to exceed the scope of the present invention.
[0094] In the several embodiments provided by the present invention, it should be understood that the disclosed equipment, devices and methods can be implemented in other ways. For example, the device embodiments described above are only schematic. For example, the division of the units is only a logical function division. There may be other division methods in actual implementation. Units with the same function may also be combined into one unit. For example, multiple units or components may be combined or integrated into another system, or some features may be ignored or not executed. In addition, the mutual coupling or direct coupling or communication connection shown or discussed may be an indirect coupling or communication connection through some interfaces, devices or units, or may be an electrical, mechanical or other form of connection.
[0095] The units described as separate components may or may not be physically separated, and the components shown as units may or may not be physical units, that is, they may be located in one place or distributed on multiple network units. Some or all of the units may be selected according to actual needs to achieve the purpose of the embodiments of the present invention.
[0096] In addition, each functional unit in each embodiment of the present invention may be integrated into one processing unit, or each unit may exist physically separately, or two or more units may be integrated into one unit. The above-mentioned integrated unit may be implemented in the form of hardware or in the form of software functional units.
[0097] If the integrated unit is implemented in the form of a software functional unit and sold or used as an independent product, it can be stored in a storage medium. Based on this understanding, the technical solution of the present invention is essentially or the part that contributes to the prior art, or all or part of the technical solution can be embodied in the form of a software product. The computer software product is stored in a storage medium, including several instructions for a computer device (which can be a personal computer, server, or network device, etc.) to perform all or part of the steps of the method described in each embodiment of the present invention. The aforementioned storage medium includes: U disk, mobile hard disk, read-only memory (ROM, Read-Only Memory), disk or optical disk and other media that can store program codes.
[0098] The above is only a specific embodiment of the present invention, but the protection scope of the present invention is not limited thereto. Any technician familiar with the technical field can easily think of various equivalent modifications or replacements within the technical scope disclosed by the present invention, and these modifications or replacements should be included in the protection scope of the present invention. Therefore, the protection scope of the present invention shall be based on the protection scope of the claims.
Claims
1. A switchable liquid inlet system, characterized in that: The invention comprises a control unit, a switching component, at least two cleaning liquid storage components for storing cleaning liquid, and a detection component for monitoring the storage amount of cleaning liquid in the cleaning liquid storage components currently connected, one end of the switching component is connected to the pipelines of at least two cleaning liquid storage components, the other end of the switching component is connected to the pipeline of the liquid outlet channel, the control unit is connected to the switching component and the detection component by signal; the liquid inlet system also comprises a pipeline sensor component, the pipeline sensor component is arranged in the liquid outlet channel, and the pipeline sensor component is connected to the control unit by signal; wherein: The detection component is used to detect the storage amount of the cleaning liquid in the cleaning liquid storage component, and send a first alarm signal to the control unit when it is lower than the alarm threshold of the storage amount of the cleaning liquid; or, the detection component is used to send the storage amount of the cleaning liquid in the cleaning liquid storage component to the control unit, so that when the control unit receives the cleaning liquid storage amount signal, it determines whether the storage amount of the cleaning liquid in the cleaning liquid storage component is lower than the liquid discharge alarm threshold according to the cleaning liquid storage amount signal, and if so, sends the first alarm signal associated with the detection component; The pipeline sensing component is used to monitor the outflow of the cleaning liquid from the liquid outlet channel in real time, and send a second alarm signal to the control unit when it is lower than the outflow alarm threshold; or, the pipeline sensing component is used to send the outflow signal of the cleaning liquid from the liquid outlet channel to the control unit, so that when the control unit receives the outflow signal of the cleaning liquid, it determines whether the outflow of the cleaning liquid from the liquid outlet channel is lower than the outflow alarm threshold according to the outflow signal of the cleaning liquid, and if so, sends a second alarm signal associated with the pipeline sensing component; Wherein, if the control unit receives a first alarm signal associated with the detection component and does not receive a second alarm signal associated with the pipeline sensing component, a first fault signal indicating that a component of the liquid inlet system is damaged is generated; If the control unit sends out the second alarm signal associated with the pipeline sensing component and does not send out the first alarm signal associated with the detection component, a second fault signal indicating that there is a pipeline fault in the liquid inlet system is generated.
2. The liquid inlet system according to claim 1, characterized in that: If the control unit receives a first alarm signal associated with the detection component and receives a second alarm signal associated with the pipeline sensing component, a switching signal is generated and sent to the switching component, so that the switching component switches from the currently connected cleaning liquid storage component to another cleaning liquid storage component; If the control unit sends out a second alarm signal associated with the pipeline sensing component and sends out a first alarm signal associated with the detection component, a switching signal is generated and sent to the switching component, so that the switching component switches from the currently connected cleaning fluid storage component to another cleaning fluid storage component.
3. The liquid inlet system according to claim 1 or 2, characterized in that: It also includes a buffer component, which is connected to the liquid outlet channel pipeline and is used for buffering and storing the cleaning liquid output from the liquid outlet channel.
4. The liquid inlet system according to claim 3, characterized in that: A pumping assembly is arranged between the buffer assembly and the switching assembly.
5. The liquid inlet system according to claim 4, characterized in that: The detection component includes a first detection unit for monitoring the storage amount of cleaning liquid in at least two of the cleaning liquid storage components and a second detection unit for monitoring the storage amount of cleaning liquid in the buffer component. The first detection unit and the second detection unit are both connected to the control unit by signal.
6. The liquid inlet system according to claim 1, characterized in that: The device components include a detection component, a pipeline sensor component, a switching component or a pumping component; and / or the pipeline failure includes a loose pipeline joint or a squeezed pipeline.
7. A liquid inlet method of a switchable liquid inlet system according to any one of claims 1 to 6, characterized in that: The method comprises: The detection component detects the storage amount of the cleaning liquid in the cleaning liquid storage component, and sends a first alarm signal to the control unit when the storage amount of the cleaning liquid is lower than the alarm threshold of the storage amount of the cleaning liquid; or the detection component sends the storage amount of the cleaning liquid in the cleaning liquid storage component to the control unit, so that when the control unit receives the cleaning liquid storage amount signal, it determines whether the storage amount of the cleaning liquid in the cleaning liquid storage component is lower than the liquid discharge alarm threshold according to the cleaning liquid storage amount signal, and if so, sends a first alarm signal associated with the detection component; The outflow of the cleaning liquid from the liquid outlet channel is monitored in real time by the pipeline sensing component, and when it is lower than the outflow alarm threshold, a second alarm signal is sent to the control unit; or, the outflow signal of the cleaning liquid from the liquid outlet channel is sent to the control unit by the pipeline sensing component, so that when the control unit receives the outflow signal of the cleaning liquid, it determines whether the outflow of the cleaning liquid from the liquid outlet channel is lower than the outflow alarm threshold according to the outflow signal of the cleaning liquid, and if so, a second alarm signal associated with the pipeline sensing component is sent; Wherein, if the control unit receives a first alarm signal associated with the detection component and does not receive a second alarm signal associated with the pipeline sensing component, a first fault signal indicating that a component of the liquid inlet system is damaged is generated; If the control unit sends out the second alarm signal associated with the pipeline sensing component and does not send out the first alarm signal associated with the detection component, a second fault signal indicating that there is a pipeline fault in the liquid inlet system is generated.
8. The liquid feeding method according to claim 7, characterized in that: The method further includes: if the control unit receives a first alarm signal associated with the detection component and receives a second alarm signal associated with the pipeline sensing component, generating and sending a switching signal to the switching component to switch the switching component from the currently connected cleaning fluid storage component to another cleaning fluid storage component; If the control unit sends out a second alarm signal associated with the pipeline sensing component and sends out a first alarm signal associated with the detection component, a switching signal is generated and sent to the switching component, so that the switching component switches from the currently connected cleaning fluid storage component to another cleaning fluid storage component.
9. The liquid feeding method according to claim 7 or 8, characterized in that: The device components include a detection component, a pipeline sensor component, a switching component or a pumping component; the pipeline failure includes a loose pipeline joint and a squeezed pipeline.
10. A liquid path system of a luminescent immunoassay analyzer, characterized in that: include: A sample reagent quantitative module for quantitatively filling sample reagents, a sample reagent cleaning and waste discharge module, a cleaning plate cleaning module, a waste liquid discharge module for discharging waste liquid, a switchable liquid inlet module for providing cleaning liquid, and a waste liquid recovery module for waste liquid recovery; The sample reagent cleaning and waste discharge module is respectively connected to the switchable liquid inlet module and the sample reagent quantitative module, and is used to extract cleaning liquid from the switchable liquid inlet module and clean the sample reagent quantitative module; The cleaning tray cleaning module is connected to the switchable liquid inlet module and is used to extract cleaning liquid from the switchable liquid inlet module and clean the cleaning tray; The waste liquid recovery module is connected to the sample reagent cleaning and waste discharge module and the waste liquid discharge module respectively, and is used to recover the cleaning waste liquid discharged from the sample reagent cleaning and waste discharge module, and to recover the cleaning waste liquid discharged from the waste liquid discharge module; The switchable liquid inlet module performs the liquid inlet method as described in any one of claims 7 to 9 above.
11. An analysis device, characterized in that: It includes a reagent sample needle module, a reagent disk module, an incubation photometry module, a magnetic separation module and a liquid inlet module, wherein: The reagent sample needle module is used to absorb reagents and samples; The reagent tray module is used to store reagents; The incubation and photometry module is used to incubate the object to be tested and detect the object to be tested to obtain the test result; The magnetic separation module is used to clean and separate the magnetic beads and unreacted waste liquid; The liquid inlet module is used to execute the liquid inlet method described in any one of claims 7 to 9.
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