Pomalidomide related substances and uses thereof
By employing HPLC detection technology and preparation methods, the problems of detecting and controlling related substances in the storage and formulation of paradefovir mesylate have been solved, thereby improving drug quality and production stability.
Patent Information
- Application Number
- CN202010632867.4
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2020-07-02
- Publication Date
- 2026-01-23
- Estimated Expiration
- 2040-07-02
AI Technical Summary
In the existing technology, paradefovir mesylate is prone to generating related substances during storage, transportation and formulation, and there is a lack of effective detection and control methods, which affects the quality of the drug.
This paper provides a method and application for the detection of related substances in paradefovir mesylate. The method uses HPLC detection technology to separate and identify related substances, and combines preparation and storage control under specific conditions to avoid the generation of related substances.
This improves the quality of paradefovir mesylate, enabling the detection and mitigation of anomalies in actual production, ensuring the drug is stored at appropriate temperatures and environments, and reducing the generation of related substances.