2results about How to "High separation yield" patented technology

The application discloses a general method for cross-coupling of nickel-catalyzed aryl halide and amine, and belongs to the field of green chemical industry. In a nitrogen-containing solvent, only a cheap and commercially available nickel salt and a base are added, and no additional ligand is designed, so that aryl halide and amine can be efficiently coupled to prepare aryl amine compounds. In the method, the nitrogen-containing solvent simultaneously serves as a metal ligand, the substrate has wide universality, has good compatibility with various functional groups, and the yield of the product separation can reach 99% at most. The process has good scalability, and has been stably produced on a hundred gram scale; the solvent and the ligand can be efficiently recycled and reused for multiple times through simple physical or chemical means. The route has the advantages of easy availability of raw materials, simple operation, high atomic economy, and compliance with the principles of green chemistry and sustainable synthesis.

This invention provides a method for preparing 2,5-furandicarboxylic acid in an acidic system, belonging to the field of bio-based chemical preparation. It is a method for synthesizing 2,5-furandicarboxylic acid by catalytic oxidation of 2,5-diformylfuran in an acidic environment. The method uses 2,5-diformylfuran as a raw material and employs an aqueous / organic two-phase catalytic system, using hydrogen peroxide to oxidize 2,5-diformylfuran to prepare 2,5-furandicarboxylic acid. In this invention, the raw material 2,5-diformylfuran and the catalyst are dissolved in the organic phase, the aqueous phase is acidic, and the oxidation product 2,5-furandicarboxylic acid precipitates in the aqueous phase. High-purity 2,5-furandicarboxylic acid can be obtained by simple filtration. The catalyst in the organic phase can be recycled multiple times. This invention does not use precious metal catalysts, does not require the addition of additional inorganic bases before or after the reaction, has simple product separation, generates little waste, and has broad application prospects.