Method for preparing aromatic aldehyde ketone by utilizing air as oxidant in hydro solvent system

Abstract

A methid for preparing aromatic keto-aldehyde in water dissolvent system employing air as oxidation agent, employing 2,2,6,6-tetramethylpiperidine-oxygen free radical (TEMPO), 1,3-dibromo-5,5-dimethylhydantoin and sodium nitrite as catalyst, water as dissolvent, air with pressure lower than 1.2 Mpa as oxidation agent, oxidating the serial aromatic alcohol and hetero-aromatic alcohol under temperature of lower than 160 Deg C to relative aromatic aldehyde and ketone.

Description

technical field

[0001] The invention relates to a method for preparing aromatic aldehydes and ketones, in particular to a method for preparing aromatic aldehydes and ketones by using water as a solvent and oxygen or air as an oxidant. Background technique

[0002] Oxidation of aromatic alcohols to aromatic aldehydes is one of the most important functional group conversion reactions in organic chemistry. Searching for efficient and clean catalytic oxidation systems has always been a research hotspot in organic chemistry.

[0003] Over the past few decades, chemists have developed two broad classes of efficient oxidation systems. One is a transition metal-catalyzed catalytic oxidation system that uses oxygen or air as an oxygen source. The products of the catalytic reaction are easily separated and there is not much waste. However, the catalyst is expensive, and commonly used metals include noble metals such as palladium (Pd) and ruthenium (Ru), and ligands with complex struc...