Drug delivery device The present application relates to a drug delivery

Abstract

The application provides a medicine delivery device, which comprises a housing, a driving mechanism, a first limiting structure, an injection mechanism and a transmission mechanism. The driving mechanism comprises an adjusting member, a first memory member and a second memory member. When the driving mechanism is in an adjusting state, the adjusting member drives the second memory member to move between an initial position and an end position. When the driving mechanism is in a delivery state, the adjusting member, the first memory member and the second memory member are relatively static. One of a first limiting member and a second limiting member of the first limiting structure is arranged on the first memory member, and the other of the first limiting member and the second limiting member is arranged on the second memory member. The first limiting member and the second limiting member are matched to limit the movement of the second memory member relative to the first memory member when the second memory member is at the end position. Through the technical scheme provided by the application, the problem that it is difficult to prevent the set dose from exceeding the remaining dose in the medicine bottle in the prior art can be solved.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of injection devices, in particular to a drug delivery device. BACKGROUND

[0002] At present, patients who need to inject drugs by themselves usually use self-administerable injection devices to inject drugs, and generally, the self-administerable drug injection device uses the principle of screw rod driving to achieve the purpose of injecting drugs. In the use process, generally, the scale barrel of the injection device is first rotated to the scale position required for injection, then the needle of the injection device is inserted into the injection site of the body, and finally the push handle is pushed to inject by using the principle of screw rod driving.

[0003] However, in the prior art, it often happens that when the remaining amount of the drug in the drug bottle assembled in the injection device is less than the required injection dose, the patient can still rotate the scale barrel for scale adjustment, and the patient cannot be reminded that the amount of drug in the drug bottle is not enough for this injection, so that the patient cannot know the injection amount of the drug this time, which exists a safety hazard. Therefore, there is a technical problem in the prior art that it is difficult to prevent the set dose from exceeding the remaining dose in the drug bottle. SUMMARY

[0004] The present application provides a drug delivery device to solve the problem of difficulty in preventing the set dose from exceeding the remaining dose in the drug bottle in the prior art.

[0005] The present application provides a drug delivery device, which comprises a housing, a driving mechanism arranged in the housing, the driving mechanism comprising an adjusting member, a first memory member and a second memory member cooperating with the first memory member, the second memory member having an initial position and an end position relative to the first memory member, the driving mechanism having an adjusting state and a delivery state, when the driving mechanism is in the adjusting state, the adjusting member drives the second memory member to move between the initial position and the end position, when the driving mechanism is in the delivery state, the adjusting member, the first memory member and the second memory member are relatively stationary; a first limiting structure comprising a first limiting member and a second limiting member, one of the first limiting member and the second limiting member being arranged on the first memory member, the other of the first limiting member and the second limiting member being arranged on the second memory member, the first limiting member cooperating with the second limiting member to limit the movement of the second memory member relative to the first memory member when the second memory member is located at the end position; an injection mechanism for injecting drugs; a transmission mechanism arranged between the driving mechanism and the injection mechanism, the driving mechanism driving the injection mechanism to inject through the transmission mechanism.

[0006] Further, the adjusting member is rotatably and axially movably arranged in the housing, the first memory member is arranged in the adjusting member, the second memory member is sleeved on the outer wall of the first memory member and threadedly cooperates with the first memory member, the first rotation-stopping structure is arranged between the second memory member and the adjusting member to limit rotation of the second memory member relative to the adjusting member.

[0007] Further, the first rotation-stopping structure comprises a first rotation-stopping protrusion and a first rotation-stopping groove, one of the first rotation-stopping protrusion and the first rotation-stopping groove is arranged on the inner wall of the adjusting member, and the other of the first rotation-stopping protrusion and the first rotation-stopping groove is arranged on the outer wall of the second memory member, the first rotation-stopping protrusion is inserted into the first rotation-stopping groove, and the first rotation-stopping protrusion and the first rotation-stopping groove both extend along the axis direction of the adjusting member.

[0008] Further, the first limiting member is a first limiting protrusion, and the second limiting member is a second limiting protrusion, the first limiting protrusion is arranged at one end of the first memory member close to the end position, the second limiting protrusion is arranged at one end of the second memory member close to the end position, and the first limiting protrusion and the second limiting protrusion are clamped to limit rotation of the second memory member relative to the first memory member.

[0009] Further, the transmission mechanism comprises a screw rod, the screw rod is drivingly connected with the injection mechanism, a first transmission member is rotatably arranged in the housing, the driving mechanism is drivingly connected with the first transmission member, the screw rod is arranged in the first transmission member, and the second rotation-stopping structure is arranged between the screw rod and the first transmission member to limit rotation of the screw rod relative to the first transmission member, a second transmission member is fixedly arranged in the housing, the screw rod is arranged in the second transmission member and threadedly cooperates with the second transmission member, and a one-way rotation structure is arranged between the first transmission member and the second transmission member, the one-way rotation structure is used to limit one-way rotation of the first transmission member relative to the second transmission member.

[0010] Further, the second transmission member has a through hole, the through hole comprises a first segment and a second segment connected with each other, the second segment is arranged towards the first transmission member, the first segment is provided with an inner thread matched with the screw rod, and one end of the first transmission member is arranged in the second segment, wherein the end of the first transmission member is provided with a reset member, the reset member is provided with a first one-way tooth, the inner wall of the second segment is provided with a second one-way tooth, and the reset member, the first one-way tooth and the second one-way tooth cooperate to limit one-way rotation of the first transmission member relative to the second transmission member, or the end of the first transmission member is provided with a first one-way tooth, the end wall of the first segment is provided with a reset member, the reset member is provided with a second one-way tooth, and the reset member, the first one-way tooth and the second one-way tooth cooperate to limit one-way rotation of the first transmission member relative to the second transmission member.

[0011] Further, the first transmission member and the housing are fixed in position in the axial direction, the first memory member is axially slidably sleeved on the outer wall of the first transmission member, and the drug delivery device further comprises: a second limiting structure arranged between the first memory member and the first transmission member, the second limiting structure being configured to limit the relative position of the first memory member and the first transmission member.

[0012] Further, the second limiting structure comprises a third limiting boss and a limiting groove, the third limiting boss being arranged on one of the first memory member and the first transmission member, and the limiting groove being arranged on the other one of the first memory member and the first transmission member, the limiting groove extending along the axial direction of the housing, the third limiting boss being slidably arranged in the limiting groove, and the third limiting boss cooperating with the limiting groove to limit the relative displacement of the first memory member and the first transmission member in the circumferential direction and the axial direction.

[0013] Further, the drive mechanism further comprises a clutch member arranged between the adjusting member and the first memory member, one end of the clutch member being provided with a first toothed structure, the other end of the clutch member being provided with a second toothed structure, the adjusting member being provided with an annular boss arranged in the circumferential direction of the adjusting member, the annular boss being provided with a third toothed structure engaged with the first toothed structure, and the end wall of the first memory member being provided with a fourth toothed structure engaged with the second toothed structure.

[0014] Further, the drug delivery device further comprises a button, a connecting member, an elastic member, and a drug container, the button being arranged at the driving end of the housing, the connecting member being arranged in the housing and located between the button and the first memory member, the elastic member being arranged between the button and the connecting member, and the drug container being arranged at the injection end of the housing; the injection mechanism comprises a push handle movably arranged in the drug container, and the transmission mechanism is drivingly connected with the push handle; the housing comprises a shell and a sleeve arranged in a split manner, or the shell and the sleeve are integrally formed.

[0015] The technical scheme of the present application is applied to the medicine delivery device which comprises a housing, a driving mechanism, a first limiting structure, an injection mechanism and a transmission mechanism. When the medicine delivery device is used to inject medicine, first, the adjusting member is adjusted to the scale of the required injection when the driving mechanism is in the adjusting state, and the second memory member moves relative to the first memory member between the initial position and the terminal position during the adjusting process. After the scale is adjusted, the injection is performed, and the second memory member is stationary relative to the first memory member during the injection, so as to realize the one-time injection memory. After the injection is performed for multiple times, if the amount of medicine in the medicine container is less than the required injection dose, since the second memory member moves a certain distance from the initial position towards the terminal position after each injection, when the adjusting member is adjusted to the scale corresponding to the required injection dose, the second memory member cannot move relative to the first memory member under the limiting action of the first limiting structure when the second memory member moves to the terminal position, so as to prevent the set dose from exceeding the remaining dose in the medicine bottle, and thus the patient can be reminded that the amount of medicine in the medicine container is not enough for the current injection. Moreover, the first limiting member and the second limiting member are used to limit the first memory member and the second memory member, so as to have the advantage of stable limiting effect. BRIEF DESCRIPTION OF DRAWINGS

[0016] The accompanying drawings, which form a part of the present application, are used to provide further understanding of the present application, and the illustrative embodiments of the present application and their description serve the purpose of explaining the present application. The present application is not limited by the accompanying drawings.

[0017] Figure 1 A structure schematic view of the medicine delivery device provided by the first embodiment of the present application is shown;

[0018] Figure 2 An exploded view of the medicine delivery device provided by the first embodiment of the present application is shown;

[0019] Figure 3 A structure schematic view of the driving mechanism in Figure 1 is shown;

[0020] Figure 4 An assembly view of the first memory member and the second memory member of the medicine delivery device provided by the first embodiment of the present application is shown;

[0021] Figure 5 A structure schematic view of the first memory member in Figure 1 is shown;

[0022] Figure 6 A structure schematic view of the second memory member in Figure 1 is shown;

[0023] Figure 7An assembly view of the adjusting member and the second memory member of the drug delivery device according to the first embodiment of the present application is shown;

[0024] Figure 8 An assembly view of the adjusting member and the second memory member of the drug delivery device according to the first embodiment of the present application is shown; Figure 1 An assembly view of the adjusting member and the second memory member of the drug delivery device according to the first embodiment of the present application is shown;

[0025] Figure 9 An assembly view of the adjusting member and the second memory member of the drug delivery device according to the first embodiment of the present application is shown; Figure 1 An assembly view of the adjusting member and the second memory member of the drug delivery device according to the first embodiment of the present application is shown;

[0026] Figure 10 An assembly view of the adjusting member and the second memory member of the drug delivery device according to the first embodiment of the present application is shown;

[0027] Figure 11 An assembly view of the adjusting member and the second memory member of the drug delivery device according to the first embodiment of the present application is shown;

[0028] Figure 12 An assembly view of the adjusting member and the second memory member of the drug delivery device according to the first embodiment of the present application is shown; Figure 1 An assembly view of the adjusting member and the second memory member of the drug delivery device according to the first embodiment of the present application is shown;

[0029] Figure 13 An assembly view of the adjusting member and the second memory member of the drug delivery device according to the first embodiment of the present application is shown; Figure 1 An assembly view of the adjusting member and the second memory member of the drug delivery device according to the first embodiment of the present application is shown;

[0030] Figure 14 An assembly view of the adjusting member and the second memory member of the drug delivery device according to the first embodiment of the present application is shown;

[0031] Figure 15 An assembly view of the adjusting member and the second memory member of the drug delivery device according to the first embodiment of the present application is shown;

[0032] Figure 16 An assembly view of the adjusting member and the second memory member of the drug delivery device according to the first embodiment of the present application is shown;

[0033] Wherein, the above figures include the following reference signs:

[0034] 10, housing; 11, outer shell; 12, sleeve; 13, first annular limiting boss;

[0035] 20, driving mechanism; 21, adjusting member; 211, annular boss; 212, third tooth structure; 22, first memory member; 221, fourth tooth structure; 23, second memory member; 231, memory member inner thread; 24, clutch member; 241, first tooth structure; 242, second tooth structure;

[0036] 30, first limiting structure; 31, first limiting member; 32, second limiting member;

[0037] 40. Injection mechanism; 41. Push handle;

[0038] 50. Transmission mechanism; 51. Screw; 52. First transmission component; 521. Reset component; 522. First one-way tooth; 523. U-shaped hole; 524. Second annular limiting boss; 53. Second transmission component; 531. Through hole; 532. Internal thread; 533. Second one-way tooth; 54. One-way rotation structure;

[0039] 60. First anti-rotation structure; 61. First anti-rotation boss; 62. First anti-rotation groove;

[0040] 70. Second anti-rotation structure;

[0041] 80. Second limiting structure; 81. Third limiting boss; 82. Limiting groove; 821. Rear end wall;

[0042] 90. Button; 100. Connector; 110. Elastic component; 120. Medicine container; 121. Medicine chamber; 122. Medicine bottle; 130. Pen cap. Detailed Implementation

[0043] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. The following description of at least one exemplary embodiment is merely illustrative and is in no way intended to limit the present invention or its application or use. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0044] like Figures 1 to 15 As shown, Embodiment 1 of the present invention provides a drug delivery device, which includes a housing 10, a drive mechanism 20, a first limiting structure 30, an injection mechanism 40, and a transmission mechanism 50. The injection mechanism 40 is used to inject drugs, and the transmission mechanism 50 is disposed between the drive mechanism 20 and the injection mechanism 40. The drive mechanism 20 drives the injection mechanism 40 to inject drugs through the transmission mechanism 50.

[0045] The drive mechanism 20 is housed within the housing 10. The drive mechanism 20 includes an adjusting member 21, a first memory element 22, and a second memory element 23 that cooperates with the first memory element 22. The drive mechanism 20 has an adjusting state and a delivery state. The second memory element 23 has an initial position and an end position relative to the first memory element 22, and can move relative to the first memory element 22 between the initial position and the end position. When the drive mechanism 20 is in the adjusting state, the adjusting member 21 drives the second memory element 23 to move between the initial position and the end position. When the drive mechanism 20 is in the delivery state, the adjusting member 21, the first memory element 22, and the second memory element 23 are relatively stationary. With this structure, the second memory element moves relative to the first memory element when adjusting the dosage, and remains stationary relative to the first memory element when delivering the drug. During multiple injections, the second memory element continuously moves from the initial position towards the end position. Specifically, the first limiting structure 30 includes a first limiting member 31 and a second limiting member 32. One of the first limiting member 31 and the second limiting member 32 is disposed on the first memory member 22, and the other of the first limiting member 31 and the second limiting member 32 is disposed on the second memory member 23. The first limiting member 31 cooperates with the second limiting member 32 to restrict the movement of the second memory member 23 relative to the first memory member 22 when the second memory member 23 is in the end position, thereby restricting the movement of the adjusting member 21.

[0046] When the drug delivery device provided in this embodiment is used for the first time, the second memory 23 is located at the initial position. When the drug delivery device is used multiple times and the drug in the drug container is just used up, the second memory 23 moves from the initial position to the end position, thereby preventing the set dose from exceeding the remaining dose in the drug bottle.

[0047] like Figure 3 and Figure 4 As shown, the second memory element 23 is located at the initial position and the final position, respectively. When adjusting the dosage, the second memory element will move relative to the first memory element under the action of the adjusting element. When delivering the drug, the second memory element is stationary relative to the first memory element. During multiple injections, the second memory element will continuously move from the initial position to the final position until the second memory element moves to the final position, at which point the drug in the drug container is just used up.

[0048] Specifically, when injecting the medicine by using the medicine delivery device, first, the adjusting member 21 is adjusted to the scale corresponding to the required injection dose, in the adjusting process, the adjusting member 21 drives the second memory member 23 to move relative to the first memory member 22 between the initial position and the terminal position, after adjusting the scale, the injection is performed, in the injection process, the second memory member 23 is static relative to the first memory member 22, thereby realizing the one-time injection memory. After injecting multiple times, if the amount of medicine in the medicine container is less than the required injection dose, because the second memory member 23 moves a certain distance from the initial position to the terminal position after each injection, when adjusting the adjusting member 21 to the scale corresponding to the required injection dose, when the second memory member 23 moves to the terminal position, under the limiting action of the first limiting structure 30, the second memory member 23 cannot move relative to the first memory member 22, and the adjusting member 21 cannot be adjusted, thereby realizing the memory function, and further reminding the patient that the amount of medicine in the medicine container is not enough for this injection. Moreover, the way of limiting the first memory member 22 and the second memory member 23 by using the first limiting member 31 and the second limiting member 32 has the advantage of stable limiting effect.

[0049] As shown in Figure 3 , Figure 6 and Figure 7 , the adjusting member 21 is rotatably and axially movably arranged in the housing 10, the adjusting member 21 has a through hole, the first memory member 22 is arranged in the through hole of the adjusting member 21, and the second memory member 23 is located between the outer wall of the first memory member 22 and the inner wall of the adjusting member 21. Specifically, the second memory member 23 is sleeved on the outer wall of the first memory member 22 and threadedly cooperates with the first memory member 22. In this embodiment, the first rotation-stopping structure 60 is arranged between the second memory member 23 and the adjusting member 21, the first rotation-stopping structure 60 is used to limit the rotation of the second memory member 23 relative to the adjusting member 21, thereby in the process of rotating the adjusting member 21, the adjusting member 21 drives the second memory member 23 to rotate on the first memory member 22, thereby realizing the axial movement of the second memory member 23. In this embodiment, the inner wall of the second memory member 23 is provided with a memory member inner thread 231.

[0050] In this embodiment, the adjusting member 21 threadedly cooperates with the housing 10. In the process of rotating the adjusting member 21, the adjusting member 21 will axially displace relative to the housing 10.

[0051] As shown in Figure 7As shown, the first anti-rotation structure 60 includes a first anti-rotation boss 61 and a first anti-rotation groove 62. One of the first anti-rotation boss 61 and the first anti-rotation groove 62 is disposed on the inner wall of the adjusting member 21, and the other of the first anti-rotation boss 61 and the first anti-rotation groove 62 is disposed on the outer wall of the second memory member 23. The first anti-rotation boss 61 is inserted into the first anti-rotation groove 62, and both the first anti-rotation boss 61 and the first anti-rotation groove 62 extend along the axial direction of the adjusting member 21. When the adjusting member 21 is rotated, under the action of the first anti-rotation boss 61 and the first anti-rotation groove 62, the second memory member 23 will rotate synchronously with the adjusting member 21. Since the second memory member is threadedly engaged with the first memory member, the second memory member will undergo axial displacement along the axial direction of the first memory member. In this embodiment, the first anti-rotation boss 61 is disposed on the inner wall of the adjusting member 21, and the first anti-rotation groove 62 is disposed on the outer wall of the second memory member 23. In other embodiments, the first anti-rotation boss 61 may be disposed on the outer wall of the second memory element 23, and the first anti-rotation groove 62 may be disposed on the inner wall of the adjusting element 21.

[0052] The number of first anti-rotation protrusions 61 and first anti-rotation grooves 62 can be one or more. In this embodiment, two first anti-rotation protrusions 61 are symmetrically arranged on the inner wall of the adjusting member 21, and two first anti-rotation grooves 62 are symmetrically arranged on the outer wall of the second memory member 23, with each first anti-rotation protrusion 61 and first anti-rotation groove 62 corresponding to the other. This structure improves both the anti-rotation effect and the stability of the second memory member during movement, as well as the structural robustness of the device.

[0053] The first limiting structure 30 includes a structure in which a limiting boss and a limiting boss cooperate, a structure in which a limiting boss and a limiting groove cooperate, and a hook structure.

[0054] like Figures 4 to 6 As shown, in this embodiment, the first limiting member 31 is a first limiting protrusion, and the second limiting member 32 is a second limiting protrusion. The first limiting protrusion is disposed at one end of the first memory member 22 near the end position, and the second limiting protrusion is disposed at one end of the second memory member 23 near the end position. When the second memory member 23 moves from the initial position to the end position, the first limiting protrusion and the second limiting protrusion engage to restrict the rotation of the second memory member 23 relative to the first memory member 22, thereby reminding the patient that the amount of medicine in the drug container is insufficient for this injection.

[0055] In the embodiment, the first memory member is provided with a plurality of first limiting bosses, the second memory member is provided with a plurality of second limiting bosses, and the plurality of first limiting bosses and the plurality of second limiting bosses are one-to-one corresponding. The plurality of first limiting bosses and the plurality of second limiting bosses are matched to improve the limiting effect and the limiting stability. In other embodiments, only one first limiting boss and one second limiting boss are provided to achieve the limiting function and simplify the structure of the device.

[0056] In order to facilitate understanding of how the memory function is achieved, the following describes the use process:

[0057] (1) Initially, the second memory member 23 is at the leftmost end (initial position) of the first memory member 22, the adjusting member 21 has a first rotation stopping boss 61, the second memory member 23 has a first rotation stopping groove 62 on the outer wall, the two structures are locked in the rotation direction and are movable in the axial direction. When the dose is adjusted, the second memory member 23 is rotated when the adjusting member 21 is adjusted in the forward direction, the second memory member 23 is threadedly connected with the first memory member 22, and the first memory member 22 does not rotate when it is adjusted in the forward direction. Therefore, when the adjusting member 21 is adjusted in the forward direction, the second memory member 23 moves rightward relative to the first memory member 22 by a corresponding number of turns. If the dose needs to be reduced, the adjusting member 21 is adjusted in the reverse direction, and the second memory member 23 moves leftward relative to the first memory member 22 by a corresponding number of turns.

[0058] (2) When the injection is performed, the position of the second memory member 23 relative to the first memory member 22 does not change.

[0059] (3) The above process is repeated.

[0060] (4) Finally, the second memory member 23 moves to the rightmost end (end position) of the first memory member 22, at which time the first limiting member and the second limiting member are locked in the forward adjustment direction and cannot be adjusted in the direction of increasing the dose. The amount of the drug liquid in the drug container that can be output at this time is exactly the dose value that has been adjusted. The dose output by the above process is the maximum output dose designed, and thus the memory function is achieved (at this time, the adjusting member 21 can be adjusted in the direction of reducing the dose).

[0061] As Figure 1 , Figures 8 to 10As shown, the transmission mechanism 50 comprises a screw rod 51, a first transmission member 52, a second transmission member 53 and a one-way rotation structure 54. The screw rod 51 is drivingly connected with the injection mechanism 40. The first transmission member 52 is rotatably arranged in the housing 10. The driving mechanism 20 is drivingly connected with the first transmission member 52. The second transmission member 53 is fixedly arranged in the housing 10. Specifically, the screw rod 51 is arranged in the first transmission member 52. A second rotation-stopping structure 70 is arranged between the screw rod 51 and the first transmission member 52. The second rotation-stopping structure 70 is used to limit the rotation of the screw rod 51 relative to the first transmission member 52. The first transmission member 52 can drive the screw rod 51 to rotate synchronously. Since the screw rod 51 is arranged in the second transmission member 53 and threadedly cooperates with the second transmission member 53, the screw rod 51 can move axially synchronously when it rotates, thereby driving the injection mechanism 40 to inject.

[0062] Specifically, the screw rod 51 is a non-circular rod. The shape and size of the inner hole of the first transmission member 52 are matched with the shape and size of the cross section of the screw rod 51, so as to form the second rotation-stopping structure 70. In this embodiment, the screw rod has a flat surface. The first transmission member has a U-shaped hole 523 which cooperates with the flat surface of the screw rod to be locked in the rotation direction and movable in the axial direction. In other embodiments, the structure of the boss and the groove can also be used to achieve the rotation-stopping effect.

[0063] In this embodiment, the one-way rotation structure 54 is arranged between the first transmission member 52 and the second transmission member 53. The one-way rotation structure 54 is used to limit the one-way rotation of the first transmission member 52 relative to the second transmission member 53, thereby enabling the first transmission member, the screw rod and the first memory member to rotate in the injection direction only, which is convenient for memory.

[0064] As shown, Figures 8 to 10 The second transmission member 53 has a through hole 531 which comprises a first section and a second section connected with each other. The second section is arranged towards the first transmission member 52. Specifically, the first section is provided with an inner thread 532 which cooperates with the screw rod 51. The screw rod can move axially when it rotates. Specifically, one end of the first transmission member 52 is arranged in the second section. The end of the first transmission member 52 is provided with a reset member 521 which is movable in the radial direction relative to the first transmission member 52. The end of the reset member 521 is provided with a first one-way tooth 522. The inner wall of the second section is provided with a second one-way tooth 533. The reset member 521, the first one-way tooth 522 and the second one-way tooth 533 cooperate to limit the one-way rotation of the first transmission member 52 relative to the second transmission member 53, i.e. the first transmission member 52 can rotate in the injection direction only relative to the second transmission member 53. In this embodiment, when the second transmission member 53 is fixed, the first transmission member 52 can rotate in the counterclockwise direction and jump. It is locked in the clockwise direction and cannot rotate in the clockwise direction, thereby achieving the function of the one-way rotation structure.

[0065] In the embodiment, the reset member 521 is a spring arm, one end of the spring arm is connected with the end of the first transmission member 52, the other end of the spring arm is a free end, and the first one-way tooth 522 is arranged on the free end of the spring arm. In other embodiments, the reset member can be arranged as an elastic member or the like, as long as the reset member can reset the first one-way tooth 522.

[0066] Specifically, the side wall of the end of the first transmission member 52 is provided with a reset member (spring arm), the spring arm extends along the circumference of the first transmission member, the spring arm is provided with the first one-way tooth 522, and the inner wall of the second section of the through hole of the second transmission member 53 is provided with the second one-way tooth 533.

[0067] In the embodiment, the end of the first transmission member 52 is provided with a plurality of reset members 521, the plurality of reset members 521 are arranged at intervals along the circumference of the first transmission member 52, and the inner wall of the second section is provided with a ring of second one-way teeth arranged along the circumference of the second transmission member, and the plurality of reset members are used to simultaneously stop rotation, which can improve the limiting effect.

[0068] As shown in Figure 14 and Figure 15 The first transmission member 52 and the housing 10 are fixed in position in the axial direction, the first memory member 22 is axially slidably sleeved on the outer wall of the first transmission member 52, and the drug delivery device further comprises a second limiting structure 80 arranged between the first memory member 22 and the first transmission member 52, the second limiting structure 80 being used to limit the relative position of the first memory member 22 and the first transmission member 52. Among them, the second limiting structure 80 for limiting the relative position of the first memory member 22 and the first transmission member 52 includes limiting the circumferential displacement and the axial displacement of the first memory member.

[0069] Specifically, the second limiting structure 80 comprises a third limiting boss 81 and a limiting groove 82, the third limiting boss 81 is arranged on one of the first memory member 22 and the first transmission member 52, the limiting groove 82 is arranged on the other one of the first memory member 22 and the first transmission member 52, the limiting groove 82 extends along the axial direction of the housing 10, the third limiting boss 81 is slidably arranged in the limiting groove 82, and the third limiting boss 81 cooperates with the limiting groove 82 to limit the relative displacement of the first memory member 22 and the first transmission member 52 in the circumferential direction and the axial direction. Since the limiting groove 82 extends along the axial direction of the housing 10, and the third limiting boss 81 is slidably arranged in the limiting groove, the first memory member cannot rotate relative to the first transmission member. During the adjustment of the adjustment member 21 to the scale required for injection, the first memory member will translate relative to the first transmission member, and when the adjustment member 21 is adjusted to the scale corresponding to the single maximum adjustable dose, the third limiting boss will abut against the rear end wall 821 of the limiting groove, thereby limiting the axial displacement of the first memory member, and further preventing the positive adjustment.

[0070] Alternatively, a limiting boss is further arranged in the limiting groove 82, and when the adjustment member 21 is adjusted to the scale corresponding to the single maximum adjustable dose, the limiting boss abuts against the third limiting boss 81, which also limits the axial displacement of the first memory member. In the embodiment, the axial displacement of the first memory member is limited by controlling the length of the limiting groove 82, which has the advantages of simple structure, easy processing and low cost compared with the way of arranging a limiting boss in the limiting groove. Specifically, the principle of limiting by the limiting boss is the same as that of limiting by the rear end wall 821 of the limiting groove, and the rear end wall 821 of the limiting groove can be regarded as a limiting boss.

[0071] In the embodiment, the third limiting boss 81 is arranged on the inner wall of the first memory member 22, and the limiting groove 82 is arranged on the outer wall of the first transmission member 52. In other embodiments, the third limiting boss 81 can be arranged on the outer wall of the first transmission member 52, and the limiting groove 82 can be arranged on the inner wall of the first memory member 22.

[0072] As shown in FIG. 1, Figure 15 In the embodiment, the first annular limiting boss 13 is arranged on the inner wall of the housing, and the second annular limiting boss 524 is arranged on the outer wall of the first transmission member 52, and the first annular limiting boss is clamped with the second annular limiting boss to limit the displacement of the first transmission member in the axial direction of the housing.

[0073] As shown in FIG. 1, Figures 11 to 13As shown, the driving mechanism 20 further comprises a clutch member 24 arranged between the adjusting member 21 and the first memory member 22, one end of the clutch member 24 is provided with a first toothed structure 241, and the other end of the clutch member 24 is provided with a second toothed structure 242. Specifically, the adjusting member 21 has an annular boss 211 arranged along the circumference of the adjusting member 21, and the side of the annular boss 211 facing the clutch member is provided with a third toothed structure 212 meshing with the first toothed structure 241, and the end wall of the first memory member 22 facing the clutch member is provided with a fourth toothed structure 221 meshing with the second toothed structure 242. Moreover, the extending direction of the teeth of the first toothed structure 241 is the same as the extending direction of the teeth of the second toothed structure 242. In the embodiment, the clutch member is a bounce gear.

[0074] As shown in Figure 3 and Figure 13 In the embodiment, the extending direction of the teeth of the first toothed structure 241 is the same as the extending direction of the teeth of the second toothed structure 242, specifically, as viewed from the same side of the clutch member 24 in the axial direction, the teeth of the first toothed structure 241 and the teeth of the second toothed structure 242 all extend in the clockwise direction or all extend in the counterclockwise direction.

[0075] In the embodiment, the extending direction of the teeth of the first toothed structure 241 is the same as the extending direction of the teeth of the second toothed structure 242, specifically, as viewed from the same side of the clutch member 24 in the axial direction, the teeth of the first toothed structure 241 and the teeth of the second toothed structure 242 all extend in the clockwise direction or all extend in the counterclockwise direction.

[0076] Specifically, in the process of positive adjustment, the adjusting member 21 rotates relative to the clutch member 24 during positive adjustment, and the clutch member 24 rotates relative to the first memory member 22 during back adjustment, so as to emit a sound for reminding, facilitating the use of the patient. Moreover, due to the same extending direction of the teeth of the first toothed structure 241 and the teeth of the second toothed structure 242, the above two one-way bounce directions are opposite.

[0077] As shown in Figures 1 to 3 The drug delivery device further comprises a button 90, a connecting member 100, an elastic member 110 and a drug container 120. The button 90 is arranged at the driving end of the housing 10, the connecting member 100 is arranged in the housing 10 and located between the button 90 and the first memory member 22, the elastic member 110 is arranged between the button 90 and the connecting member 100, and the drug container 120 is arranged at the injection end of the housing 10. Specifically, the injection mechanism 40 comprises a push handle 41 movably arranged in the drug container 120, and the transmission mechanism 50 is drivingly connected with the push handle 41. In the embodiment, the housing 10 comprises a housing 11 and a sleeve 12 arranged separately, so as to facilitate assembly. In the embodiment, the elastic member is a spring.

[0078] In the embodiment, the drug container 120 comprises a drug chamber 121 and a drug bottle 122, and the pusher 41 is arranged in the drug bottle, and a cap 130 is arranged outside the drug chamber.

[0079] Further, the driving end of the housing refers to the right end in the figure, and the user can press the button or rotate the adjusting member at the driving end by hand, and the injection end of the housing refers to the left end in the figure, and the drug bottle is arranged at the injection end. Figure 1 Figure 1

[0080] Further, the pitch between the adjusting member and the housing in the drug delivery device is greater than the pitch between the screw rod and the second transmission member, that is, the pitch of the thread of the adjusting member directly contacted by the operator is greater, and the pitch of the threaded part of the screw rod for pushing the rubber plug in the drug container to advance is smaller. Since the unit of the drug liquid is small, for example, 0.01 ml, the axial dimension occupied in the drug container is about 0.14 mm, and the size is small, and if the rubber plug is directly pushed, the precision is high, and it is not conducive to injection. Now, by the principle of the speed reducer, when the screw rod advancing the rubber plug moves by 1 unit, that is, 0.14 mm, the operator can directly drive the movement distance of about 0.56 mm, that is, the second part of the thread is amplified by 4 times, thereby reducing the injection error.

[0081] In the embodiment, the drug delivery device comprises a syringe, in particular a disposable injection pen.

[0082] In the embodiment, the specific structure of the injection mechanism and the transmission mechanism can be changed according to the actual situation, as long as the injection and transmission can be smoothly carried out.

[0083] In the embodiment, the driving connection between the component A and the component B means that the component A drives the component B to move, and the movement includes rotation and translation. The component A can be directly connected with the component B in driving, or the component A can be indirectly connected with the component B in driving through a transmission member. For example, the screw rod 51 is connected with the injection mechanism 40 in driving, the end of the screw rod 51 is directly connected with the pusher 41, when the screw rod 51 moves axially, the pusher 41 is directly driven to move axially, and then the injection is completed, or the screw rod 51 is connected with the pusher 41 through an intermediate connecting member, the screw rod 51 transmits the driving force to the pusher 41 through the intermediate connecting member, and then the pusher 41 is driven to move axially.

[0084] The embodiment two of the application provides a drug delivery device, and the difference between the embodiment two and the embodiment one is that in the embodiment two, the end of the first transmission member 52 is provided with a first one-way tooth 522, the end wall of the first section is provided with a reset member 521, the reset member 521 is provided with a second one-way tooth 533, and the reset member 521, the first one-way tooth 522 and the second one-way tooth 533 are matched to limit the one-way rotation of the first transmission member 52 relative to the second transmission member 53.

[0085] ​​Specifically, the end wall of the first transmission member 52 is provided with a first one-way tooth 522, one end of a reset member 521 is arranged on the end wall of the first section of the second transmission member 53, the other end of the reset member 521 is a free end, a second one-way tooth 533 is arranged on the free end of the reset member 521, the free end of the reset member 521 can move relative to the second transmission member 53 in the axial direction, and the reset member 521, the first one-way tooth 522 and the second one-way tooth 533 cooperate to limit the one-way rotation of the first transmission member 52 relative to the second transmission member 53, that is, the first transmission member 52 can only rotate relative to the second transmission member 53 in the injection direction.

[0086] As shown in Figure 16 Embodiment three of the present application provides a drug delivery device, and the difference between embodiment three and embodiment one is that, in embodiment three, the shell 11 and the sleeve 12 are integrally formed, which is convenient for processing and can improve the integration of the device.

[0087] In order to facilitate understanding of the drug delivery device provided by the embodiments, the following describes the use process, and the operation mode of the drug delivery device includes:

[0088] (1) Positive adjustment: rotation out (increase the scale) of the adjusting member 21, fixed shell, clockwise rotation of the adjusting member 21, at this time the scale can be observed to be increased through the window on the shell;

[0089] (2) Back adjustment: rotation in (decrease the scale) of the adjusting member 21, if more than the expected scale is adjusted by mistake, the adjusting member 21 can be counterclockwise, at this time the scale is decreased;

[0090] (3) Injection: when the scale is adjusted to the specified position, hold the shell, press the button 90 to push forward, and transmit to the adjusting member 21 through the connecting member 100, the first memory member 22 and the clutch member 24, so that the adjusting member 21 bears the axial thrust, and the adjusting member 21 rotates due to the threaded cooperation with the shell 10, so as to finally transmit to the screw rotation, so that the screw is axially displaced relative to the second transmission member, and the injection effect is achieved.

[0091] Moreover, the force values brought by the positive adjustment and the back adjustment cannot move the screw, the left screw does not rotate, and the situation of injecting medicine does not occur, so the adjustment of the metering can be increased or decreased at will.

[0092] The device provided by the embodiments has the following beneficial effects:

[0093] (1) It has a memory function, and through the cooperation between the first memory member and the second memory member, when the amount of medicine contained in the medicine container is less than the injection dose required by the patient, the patient can only adjust to the remaining amount of medicine in the medicine container, so as to prompt the patient that the amount of medicine is insufficient, and the new injection pen can be prepared in advance.

[0094] (2) With the structure of one-way rotation, the function of back adjustment can be realized;

[0095] (3) With the structure of sound production, sound can be produced in forward adjustment and back adjustment;

[0096] (4) With the cooperation of the third limiting boss 81 and the limiting groove 82, the structure of single maximum adjustable dose can be realized;

[0097] (5) The injection can be self-injected without frequent visits to doctors for treatment; the structure is simple, the volume is moderate, and the device can be conveniently carried; the patient can accurately set the required injection dose of the drug; the device is more solid and durable than the traditional syringe; the injection speed can be controlled by the user to reduce the pain.

[0098] It should be noted that the terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of example embodiments in accordance with the present application. As used herein, the singular forms "a", "an" and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise. It will be further understood that the terms "comprises" and / or "comprising," when used in this specification, specify the presence of stated features, steps, operations, elements, components, and / or groups thereof, but do not preclude the presence or addition of one or more other features, steps, operations, elements, components, and / or groups thereof.

[0099] The relative arrangement of parts and steps, numerical expressions, and numerical values set forth in the examples are not intended to limit the scope of the application, unless otherwise specifically stated. At the same time, it should be understood that the sizes of the various parts shown in the drawings are not drawn in proportion to the actual proportions. The techniques, methods and devices known to those skilled in the relevant art can not be discussed in detail, but should be considered as part of the authorized description, if appropriate. In all examples shown and discussed herein, any specific value should be interpreted as merely exemplary, and not as a limitation. Therefore, other examples of exemplary embodiments can have different values. It should be noted that similar reference numbers and letters represent similar items in the following drawings, so further discussion is not necessary if an item is defined in one drawing.

[0100] In the description of the present application, it should be understood that the orientation words such as "front, back, up, down, left, right", "transverse, vertical, perpendicular, horizontal" and "top, bottom" and the like indicate the orientation or positional relationship shown in the drawings, which is only for the convenience of describing the present application and simplifying the description, and does not indicate and imply that the indicated device or element must have a particular orientation or be constructed and operated in a particular orientation, unless otherwise stated, therefore it cannot be understood as a limitation on the scope of protection of the present application; the orientation words "inner, outer" refer to the inner and outer of the contour of each part itself.

[0101] For purposes of the description hereinafter, the orientations in the various drawings will be described as shown in the drawings. However, it will be understood that the device can assume different orientations, e.g. viewed from the bottom, based on the application. Accordingly, the illustrative terms such as "above", "below", "upper", "lower", and the like are used as a shorthand notations to convey the relative positions of an object or feature as shown in the figures. It will be further appreciated that the spatially relative terms are intended to encompass different orientations of the device in use or operation in addition to the orientations depicted in the figures. For example, if the device described is turned over, then a depiction that was previously described as "above" other parts or steps would then be oriented "below" other parts or steps. Thus, the exemplary term "above" can encompass both an "above" and "below" position depending on the particular orientation being referred to. Similarly, the terms "above" and "below" can include vertical orientations of the device as well as horizontal orientations of the device. The device can be otherwise oriented (rotated 90 degrees or at other orientations) and the spatially relative descriptors used herein interpreted accordingly.

[0102] In addition, it should be pointed out that the use of the terms "first", "second" and the like does not indicate any special meaning, but is merely intended to distinguish the corresponding parts, and therefore should not be interpreted as limiting the scope of protection of the present application.

[0103] The preferred embodiments of the present application have been described above with the purpose to enable not to limit the scope of protection of the present application. As a person skilled in the art can make various modifications and changes to the present application without departing from the spirit and principles of the present application, it should be understood that any modification, equivalent replacement, improvement, etc. made within the scope of the present application shall fall within the scope of the present application.

Claims

1. A drug delivery device, characterized by, The drug delivery device comprises: a housing (10); a drive mechanism (20) arranged in the housing (10), the drive mechanism (20) comprising an adjusting member (21), a first memory member (22) and a second memory member (23) cooperating with the first memory member (22), the second memory member (23) having an initial position and an end position relative to the first memory member (22), the drive mechanism (20) having an adjusting state and a delivery state, when the drive mechanism (20) is in the adjusting state, the adjusting member (21) drives the second memory member (23) to move between the initial position and the end position, when the drive mechanism (20) is in the delivery state, the adjusting member (21), the first memory member (22) and the second memory member (23) are relatively static; a first limiting structure (30) comprising a first limiting member (31) and a second limiting member (32), one of the first limiting member (31) and the second limiting member (32) is arranged on the first memory member (22), the other of the first limiting member (31) and the second limiting member (32) is arranged on the second memory member (23), the first limiting member (31) cooperates with the second limiting member (32) to limit the movement of the second memory member (23) relative to the first memory member (22) when the second memory member (23) is in the end position; an injection mechanism (40) for injecting drugs; a transmission mechanism (50) arranged between the drive mechanism (20) and the injection mechanism (40), the drive mechanism (20) drives the injection mechanism (40) to inject through the transmission mechanism (50); the drive mechanism (20) further comprises a clutch member (24) arranged between the adjusting member (21) and the first memory member (22), one end of the clutch member (24) is provided with a first tooth profile structure (241), the other end of the clutch member (24) is provided with a second tooth profile structure (242), the adjusting member (21) has an annular boss (211) arranged circumferentially along the adjusting member (21), the annular boss (211) is provided with a third tooth profile structure (212) engaged with the first tooth profile structure (241), the end wall of the first memory member (22) is provided with a fourth tooth profile structure (221) engaged with the second tooth profile structure (242); the drug delivery device further comprises a button (90), a connecting member (100), an elastic member (110) and a drug container (120), the button (90) is arranged at the driving end of the housing (10), the connecting member (100) is arranged in the housing (10) and located between the button (90) and the first memory member (22), the elastic member (110) is arranged between the button (90) and the connecting member (100), and the drug container (120) is arranged at the injection end of the housing (10).

2. The drug delivery device of claim 1, wherein, The adjusting member (21) is rotatable and axially movable arranged in the housing (10), the first memory member (22) is arranged in the adjusting member (21), the second memory member (23) is sleeved on the outer wall of the first memory member (22) and threadedly cooperates with the first memory member (22), the first rotation-stopping structure (60) is arranged between the second memory member (23) and the adjusting member (21) to limit the rotation of the second memory member (23) relative to the adjusting member (21).

3. The drug delivery device of claim 2, wherein, The first rotation-stopping structure (60) comprises a first rotation-stopping boss (61) and a first rotation-stopping groove (62), one of the first rotation-stopping boss (61) and the first rotation-stopping groove (62) is arranged on the inner wall of the adjusting member (21), the other of the first rotation-stopping boss (61) and the first rotation-stopping groove (62) is arranged on the outer wall of the second memory member (23), the first rotation-stopping boss (61) is inserted into the first rotation-stopping groove (62), and the first rotation-stopping boss (61) and the first rotation-stopping groove (62) both extend along the axis direction of the adjusting member (21).

4. A drug delivery device as in any of claims 1-3, wherein, The first limiting member (31) is a first limiting boss, the second limiting member (32) is a second limiting boss, the first limiting boss is arranged on one end of the first memory member (22) close to the end position, the second limiting boss is arranged on one end of the second memory member (23) close to the end position, and the first limiting boss and the second limiting boss are clamped to limit the rotation of the second memory member (23) relative to the first memory member (22).

5. The drug delivery device of claim 1, wherein The transmission mechanism (50) comprises: a screw rod (51) drivingly connected with the injection mechanism (40); a first transmission member (52) rotatably arranged in the housing (10), the drive mechanism (20) being drivingly connected with the first transmission member (52), the screw rod (51) being arranged in the first transmission member (52), and a second rotation-stopping structure (70) being arranged between the screw rod (51) and the first transmission member (52) to limit the rotation of the screw rod (51) relative to the first transmission member (52); a second transmission member (53) fixedly arranged in the housing (10), the screw rod (51) being arranged in the second transmission member (53) and threadedly cooperating with the second transmission member (53); a one-way rotation structure (54) arranged between the first transmission member (52) and the second transmission member (53), the one-way rotation structure (54) being used to limit the one-way rotation of the first transmission member (52) relative to the second transmission member (53).

6. The drug delivery device of claim 5, wherein, The second transmission member (53) has a through hole (531) comprising a first section and a second section connected with each other, the second section is arranged towards the first transmission member (52), the first section is provided with an inner thread (532) matched with the screw rod (51), one end of the first transmission member (52) is arranged in the second section, wherein, an end of the first transmission member (52) is provided with a reset member (521), the reset member (521) is provided with a first one-way tooth (522), an inner wall of the second section is provided with a second one-way tooth (533), the reset member (521), the first one-way tooth (522) and the second one-way tooth (533) are matched to limit the one-way rotation of the first transmission member (52) relative to the second transmission member (53), or an end of the first transmission member (52) is provided with a first one-way tooth (522), an end wall of the first section is provided with a reset member (521), the reset member (521) is provided with a second one-way tooth (533), the reset member (521), the first one-way tooth (522) and the second one-way tooth (533) are matched to limit the one-way rotation of the first transmission member (52) relative to the second transmission member (53).

7. The drug delivery device of claim 5, wherein, The first transmission member (52) and the housing (10) are fixed in position in the axial direction, the first memory member (22) is axially slidably sleeved on the outer wall of the first transmission member (52), and the drug delivery device further comprises: a second limiting structure (80) arranged between the first memory member (22) and the first transmission member (52), the second limiting structure (80) is used to limit the relative position of the first memory member (22) and the first transmission member (52).

8. The drug delivery device of claim 7, wherein, The second limiting structure (80) comprises a third limiting boss (81) and a limiting groove (82), the third limiting boss (81) is arranged on one of the first memory member (22) and the first transmission member (52), the limiting groove (82) is arranged on the other one of the first memory member (22) and the first transmission member (52), the limiting groove (82) extends along the axial direction of the housing (10), the third limiting boss (81) is slidably arranged in the limiting groove (82), and the third limiting boss (81) and the limiting groove (82) are matched to limit the relative displacement of the first memory member (22) and the first transmission member (52) in the circumferential and axial directions.

9. The drug delivery device according to claim 8, wherein When the adjusting member (21) is adjusted to the scale corresponding to the single maximum adjustable dose, the third limiting boss (81) abuts against the rear end wall (821) of the limiting groove (82); or a limiting boss is arranged in the limiting groove (82), and when the adjusting member (21) is adjusted to the scale corresponding to the single maximum adjustable dose, the limiting boss abuts against the third limiting boss (81) to limit the axial displacement of the first memory member (22); A first annular limiting boss (13) is arranged on the inner wall of the shell (10), a second annular limiting boss (524) is arranged on the outer wall of the first transmission member (52), and the first annular limiting boss (13) and the second annular limiting boss (524) are clamped to limit the axial displacement of the first transmission member (52) in the shell (10).

10. The drug delivery device according to claim 1, wherein The extension direction of the teeth of the first toothed structure (241) is the same as the extension direction of the teeth of the second toothed structure (242); The injection mechanism (40) comprises a push handle (41) movably arranged in the drug container (120), and the transmission mechanism (50) is drivingly connected with the push handle (41); The shell (10) comprises a shell (11) and a sleeve (12) arranged in a split manner, or the shell (11) and the sleeve (12) are an integral structure.

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