Valve clippers and valve repair systems

Abstract

The present invention relates to a valve clipper and valve repair system. The valve clipper comprises a central shaft, a sliding member, a locking mechanism, and a plurality of clamping arms. The inner wall of the central shaft is provided with a first internal thread. The plurality of clamping arms are disposed around the outer periphery of the central shaft. The sliding member is slidably disposed within the central shaft, and the sliding member and the clamping arms are connected by a pivot mechanism so that the clamping arms rotate in accordance with the axial sliding of the sliding member. The locking mechanism comprises a control member and a locking sleeve. The locking sleeve is rotatably sleeved on the outer surface of the sliding member. The outer wall of the locking sleeve is provided with a first external thread for mating with the first internal thread. The control member is connected to the locking sleeve and can drive the locking sleeve to rotate so that the locking sleeve remains connected to the central shaft while remaining connected to the sliding member. The valve clipper of the present invention does not wear between the locking sleeve and the central shaft after locking, and the threaded connection is stable and reliable, thereby solving the problem of poor reliability of the valve clipper.

Description

Technical Field

[0001] The present invention belongs to the technical field of medical devices, and in particular relates to a valve clipper and a valve repair system. Background Art

[0002] Heart valves refer to the valves between the atria and ventricles or between the ventricles and arteries. The atrioventricular valves include the mitral valve and the tricuspid valve. The mitral valve is two valves attached to the periphery of the left atrioventricular orifice, connected to the papillary muscles by chordae tendineae, and has the function of preventing blood from the left ventricle from flowing back to the left atrium. Mitral regurgitation is a poor anastomosis of the anterior and posterior leaflets of the mitral valve due to organic or functional changes in the mitral valve leaflets and their related structures. During mitral regurgitation, blood will flow back from the left ventricle to the left atrium, causing a series of pathophysiological changes.

[0003] Surgical valve repair or replacement is considered the standard treatment for this type of disease. However, surgery has disadvantages such as great trauma, significant postoperative pain, slow recovery, and high risk. In recent years, interventional treatment of heart valve disease has developed rapidly due to its advantages such as less trauma, relative safety, and good efficacy. Among them, the valve repair method developed based on the principle of surgical valve edge-to-edge suturing technology has been recognized for its high safety, simple technical principles, and high feasibility. During this operation, the valve repair system needs to be disengaged after the clamp arm of the valve clip is locked, so that the valve clip remains in the patient's body.

[0004] The locking mechanism of a conventional valve clipper includes a retaining frame, a baffle, and an arched spring. In the locked state, the arched spring abuts the baffle and applies force, tilting it and locking it against the sliding member. To unlock, the operator pulls the baffle to return it to a horizontal position, freeing it from the sliding member. However, the prolonged contact between the baffle and the sliding member can easily cause wear on the sliding member, posing a risk of locking failure. Consequently, existing valve clippers have poor reliability. Summary of the Invention

[0005] The present invention aims to at least address the problem of poor reliability of valve clippers. This objective is achieved through the following technical solutions:

[0006] A first aspect of the present invention provides a valve clipper, comprising:

[0007] A central shaft cylinder, wherein the inner wall of the central shaft cylinder is provided with a first internal thread;

[0008] A plurality of clamping arms, wherein the plurality of clamping arms are arranged around the periphery of the central shaft cylinder;

[0009] a sliding member, the sliding member being slidably disposed in the central shaft cylinder, the sliding member being connected to the clamping arm via a pivot mechanism so that the clamping arm rotates according to the axial sliding of the sliding member;

[0010] A locking mechanism, the locking mechanism includes a control member and a locking sleeve, the locking sleeve is rotatably sleeved on the outside of the sliding member, the outer wall of the locking sleeve is provided with a first external thread for cooperating with the first internal thread, the control member is connected to the locking sleeve and can drive the locking sleeve to rotate, so that the locking sleeve is connected to the central shaft cylinder while remaining connected to the sliding member.

[0011] The valve clipper provided in the embodiment of the present invention has the following advantages:

[0012] In the valve clamper proposed in an embodiment of the present invention, the locking sleeve is always rotationally connected to the sliding member. When the clamp arm completes clamping and needs to be locked, the operator can use the control member to control the rotation of the locking sleeve so that it extends into the central shaft cylinder and is threadedly connected to the central shaft cylinder. At this time, the locking sleeve is simultaneously connected to the sliding member and the central shaft cylinder, thereby limiting the axial sliding of the sliding member, thereby preventing the clamp arm from rotating. The valve clamper proposed in this embodiment is not only easy to operate when locking, but also no wear will occur between the locking sleeve and the central shaft cylinder after locking, and the threaded connection method is stable and reliable, which solves the problem of poor reliability of the valve clamper.

[0013] In addition, the valve clipper according to the embodiment of the present invention may also have the following technical features:

[0014] In some embodiments of the present invention, the outer wall of the sliding member is provided with a second external thread, the inner wall of the locking sleeve is provided with a second internal thread matching the second external thread, and the axial length of the second external thread is greater than the axial length of the second internal thread.

[0015] In some embodiments of the present invention, the control member is shaped like a cylinder, is rotatably disposed between the central shaft and the sliding member, and a distal end of the control member is connected to the locking sleeve.

[0016] In some embodiments of the present invention, at least one limiting groove is recessed in the proximal portion of the locking sleeve, and a limiting protrusion is provided on the control member, and the limiting protrusion is inserted into the limiting groove.

[0017] In some embodiments of the present invention, two limiting grooves are provided, and the two limiting grooves are symmetrically arranged on both sides of the central hole of the locking sleeve and are respectively communicated with the central hole.

[0018] In some embodiments of the present invention, the depth of the limiting groove is smaller than the length of the locking sleeve, and the second internal thread is provided on the hole section of the center hole between the bottom surface of the limiting groove and the distal end surface of the locking sleeve.

[0019] In some embodiments of the present invention, two limiting protrusions are provided, and the two limiting protrusions are symmetrical about the axis of the control member.

[0020] In some embodiments of the present invention, the control member is configured as a shape memory alloy tube, and / or the limiting protrusion is integrally formed on the control member.

[0021] In some embodiments of the present invention, the pivot mechanism includes a base and a linkage arm, the linkage arm is rotationally connected to the base and the clamping arm respectively, and the base is fixedly connected to the sliding member.

[0022] A second aspect of the present invention provides a valve repair system, which includes a valve clamp according to any of the above embodiments and a delivery device, wherein the delivery device is detachably connected to the valve clamp to deliver the valve clamp to a set position, and the delivery device includes a driving member, which is connected to the sliding member of the valve clamp to drive the sliding member to slide.

[0023] The valve repair system proposed in the embodiment of the present invention has the same advantages as the valve clipper proposed in any of the above embodiments, which will not be described in detail here. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] The following is a brief introduction to the drawings in the implementation manner. Those skilled in the art can also derive other drawings based on these drawings without making any creative efforts.

[0025] Figure 1 Schematic diagram of the structure of the valve clipper (with the clip arms deployed) according to an embodiment of the present invention;

[0026] Figure 2 Schematic diagram of the structure of the valve clipper (with the clip arms closed) according to an embodiment of the present invention;

[0027] Figure 3 This is a front view of a partial structure of the valve clipper (the locking sleeve and the central shaft cylinder are not engaged) according to an embodiment of the present invention;

[0028] Figure 4 for Figure 3 Cross-sectional view in the AA direction;

[0029] Figure 5 This is a partial structural front view of the valve clipper (locking sleeve and central shaft cylinder matched) according to an embodiment of the present invention;

[0030] Figure 6 for Figure 5 Cross-sectional view in the middle BB direction;

[0031] Figure 7Schematic diagram of the structure of the control component in the valve clipper according to an embodiment of the present invention;

[0032] Figure 8 Schematic diagram of the structure of the locking sleeve in the valve clipper according to an embodiment of the present invention;

[0033] Figure 9 for Figure 8 A front view of the locking sleeve shown;

[0034] Figure 10 for Figure 9 Cross-sectional view in CC direction;

[0035] Figure 11 Schematic diagram of the structure of a valve repair system according to an embodiment of the present invention;

[0036] Figure 12 It is a cross-sectional schematic diagram of the cooperation between the driving component and the sliding component in the valve repair system according to an embodiment of the present invention.

[0037] The symbols in the accompanying drawings represent the following:

[0038] 1000, valve repair system;

[0039] 100. Valve clip;

[0040] 10. Central shaft; 101. First internal thread;

[0041] 20. Clamping arm; 201. Avoidance groove; 202. Connecting ear;

[0042] 30. Sliding member; 31. Sliding rod; 301. Second external thread;

[0043] 40. Pivoting mechanism; 41. Base; 42. Linkage arm;

[0044] 50. Locking mechanism; 51. Control member; 511. Limiting protrusion; 52. Locking sleeve; 521. First external thread; 522. Second internal thread; 523. Limiting groove; 524. Center hole;

[0045] 60. Capture components;

[0046] 710. Handle; 720. Sheath; 730. Bending mechanism; 740. Driving component. DETAILED DESCRIPTION

[0047] As described in the background art, taking mitral valve repair surgery as an example, after the clamping arms of a valve clipper have clamped the valve, they need to be locked, i.e., prevented from rotating and unfolding. In some existing valve clippers, the locking mechanism utilizes an arched spring to apply force to a baffle, which then locks the sliding member when the baffle tilts. However, due to the baffle being stuck on the outer wall of the sliding member for a long time, the sliding member can easily wear out, thus posing a risk of locking failure. To address the above-mentioned issues, the present invention provides a valve clipper and valve repair system, wherein the valve clipper is provided with a control member and a locking sleeve. When the clamping arms have completed clamping and need to be locked, the operator can use the control member to control the locking sleeve to rotate, threading it into a central shaft while maintaining its connection with the sliding member. This prevents the axial sliding of the sliding member, thereby limiting the rotation of the clamping arms. This not only reduces the difficulty of operation but also provides excellent locking stability, greatly reducing the possibility of locking failure.

[0048] The following will refer to the drawings in the embodiments of the present invention. The terms used in the text are only for the purpose of describing specific example implementation methods and are not to be understood as limiting the present invention. For example, the terms "including" and "having" not only indicate the existence of the stated features, but also do not exclude the existence of other features; the terms "first" and "second" do not imply a sequence or order; the terms "inside", "outside", "above", and "below" are only for the convenience of describing the relationship of one feature relative to another feature shown in the drawings, and do not indicate that they must have a specific orientation. It should be noted that in the field of interventional medical devices, the proximal end refers to the end closer to the operator, and the distal end refers to the end farther from the operator; the axial direction refers to the direction parallel to the line connecting the distal center and the proximal center of the medical device in its natural state. In the description of the present invention, the above definitions are only for the convenience of expression and are not to be understood as limiting the present invention.

[0049] See also Figures 1 to 6 An embodiment of the first aspect of the present invention provides a valve clip 100, comprising a central barrel 10, a sliding member 30, a locking mechanism 50, and a plurality of clamping arms 20. The inner wall of the central barrel 10 is provided with a first internal thread 101; the plurality of clamping arms 20 are disposed around the outer periphery of the central barrel 10; the sliding member 30 is slidably disposed within the central barrel 10, and the sliding member 30 and the clamping arms 20 are connected by a pivot mechanism 40 so that the clamping arms 20 rotate in accordance with the axial sliding of the sliding member 30; the locking mechanism 50 comprises a control member 51 and a locking sleeve 52. The locking sleeve 52 is rotatably sleeved on the outer surface of the sliding member 30, and the outer wall of the locking sleeve 52 is provided with a first external thread 521 for mating with the first internal thread 101. The control member 51 is connected to the locking sleeve 52 and can drive the locking sleeve 52 to rotate, so that the locking sleeve 52 is connected to the central barrel 10 while remaining connected to the sliding member 30.

[0050] The valve clip 100 proposed in this embodiment can be used as an edge-to-edge repair implant in the field of interventional cardiac disease treatment. The valve clip 100 proposed in this embodiment can reach a designated location via a minimally invasive portal through the body's surface and blood vessels, thereby repairing heart valves (including but not limited to the mitral valve, tricuspid valve, aortic valve, and pulmonary valve). Understandably, since the valve clip 100 needs to maintain the clamped state by locking the clamping arms 20 after clamping the heart valve to ensure it remains in the patient's body, the valve clip 100 requires high locking stability. In this embodiment, the clamp arm 20 can rotate as the sliding member 30 slides. When the locking sleeve 52 is not connected to the central shaft tube 10, the sliding member 30 can slide axially, driving the clamp arm 20 to open and close freely without unlocking. When the clamp arm 20 completes the clamping, the operator can use the control member 51 to drive the locking sleeve 52 to rotate until the locking sleeve 52 is threadedly connected to the central shaft tube 10, thereby limiting the expansion of the clamp arm 20 by preventing the sliding member 30 from sliding, thereby locking the clamp arm 20. This locking method is easy to operate and will not cause wear and failure. Compared with the existing technology, it is more stable and reliable, and solves the problem of poor reliability of the valve clamper 100.

[0051] In the valve clipper 100 proposed in this embodiment, the sliding member 30 can slide axially, thereby driving the clamping arm 20 to rotate, expand or close. The linkage relationship between the sliding member 30 and the clamping arm 20 is described in detail below in the embodiment of the overall structure and principle of the valve clipper 100. Figure 1 、 Figures 3 to 6 In this embodiment, the locking mechanism 50 includes a control member 51 and a locking sleeve 52. The locking sleeve 52 is rotatably sleeved on the outside of the sliding member 30. That is, under the drive of the control member 51, the locking sleeve 52 can rotate on the basis of maintaining the sleeve connection with the sliding member 30, and cooperates with the first internal thread 101 on the central shaft tube 10 through the first external thread 521, that is, it can be threadedly connected with the central shaft tube 10. Figure 6 As shown, the locking sleeve 52 is connected to the central shaft tube 10 and the sliding member 30 at the same time. At this time, the sliding member 30 cannot move in the axial direction and the clamping arm 20 cannot rotate.

[0052] In this embodiment, the central shaft tube 10 is configured as a cylindrical structure. Based on the above embodiment, the first internal thread 101 is provided on the inner wall near the distal end of the central shaft tube 10. For example, please continue to refer to Figure 4The first internal thread 101 can be spirally extended from the distal end of the central cylinder 10 toward the proximal end, or can be spirally extended from a location spaced a distance from the distal end of the central cylinder 10 toward the proximal end, which is not specifically limited in this embodiment. In this embodiment, the locking sleeve 52 can also be configured as a cylindrical structure, and the axial length of the first external thread 521 can be equal to or less than the axial length of the locking sleeve 52, which is not specifically limited in this embodiment.

[0053] Furthermore, the locking sleeve 52 and the sliding member 30 may be rotatably connected by a threaded connection, such as Figure 3 and Figure 4 As shown, in some embodiments of the present invention, the outer wall of the sliding member 30 is provided with a second external thread 301, and the inner wall of the locking sleeve 52 is provided with a second internal thread 522. Thus, the locking sleeve 52, which is sleeved on the outside of the sliding member 30, is threadedly connected to the sliding member 30 by means of the second internal thread 522 cooperating with the second external thread 301. On this basis, the axial length of the second external thread 301 is greater than the axial length of the second internal thread 522. Therefore, when the locking sleeve 52 rotates under the drive of the control member 51, the second internal thread 522 and the second external thread 301 can always maintain cooperation. Further, when the locking sleeve 52 is threadedly connected to the central shaft tube 10, the locking sleeve 52 still remains connected to the sliding member 30. This arrangement ensures the reliability of the locking.

[0054] In this embodiment, the control member 51 is connected to the locking sleeve 52. The operator can operate the control member 51 to drive the locking sleeve 52 to rotate. Figure 3 and Figure 4 As shown, in some embodiments of the present invention, the control member 51 is cylindrical in shape and rotatably disposed between the central shaft 10 and the sliding member 30. The distal end of the control member 51 is connected to the locking sleeve 52 in a detachable manner, so that when locking is completed, the control member 51 can be decoupled and withdrawn. In an optional embodiment, the control member 51 is threadedly connected to the locking sleeve 52, and the direction of thread engagement is opposite to the direction of engagement between the first internal thread 101 and the first external thread 521. In another optional embodiment, the distal end of the control member 51 is plugged into the locking sleeve 52, and the locking sleeve 52 can rotate with the control member 51.

[0055] In some embodiments of the present invention, the control member 51 is configured as a shape memory alloy tube. For example, the control member 51 can be configured as a nickel-titanium alloy tube. It can be understood that one end of the control member 51 is connected to the locking sleeve 52, and the other end extends toward the proximal end for the operator to operate and rotate. Since in the valve repair system, the delivery sheath for delivering the valve clipper 100 needs to bend in the patient's body to reach the target position along the set direction, the control member 51 in this embodiment is configured as a shape memory alloy tube, which can bend when the delivery sheath bends, and can also restore to the initial state according to the shape memory characteristics.

[0056] Based on the above embodiment, taking the distal end of the control member 51 being inserted into the locking sleeve 52 as an example, please refer to Figure 4 and Figures 6 to 8 In this embodiment, the locking sleeve 52 is also configured as a cylindrical structure, that is, the locking sleeve 52 has a central hole 524 arranged to pass through in the axial direction. On this basis, the proximal end of the locking sleeve 52 is recessed with at least one limiting groove 523, and the distal end of the control member 51 can be inserted into the limiting groove 523. Therefore, when the control member 51 rotates, the locking sleeve 52 can rotate with the control member 51.

[0057] Furthermore, in some embodiments of the present invention, one or more limiting grooves 523 are provided. Accordingly, a limiting protrusion 511 is provided at the distal end of the control member 51. The limiting protrusion 511 is inserted into the limiting groove 523. The number of limiting protrusions 511 is the same as the number of limiting grooves 523. It can be understood that the provision of the limiting grooves 523 facilitates the control member 51 to drive the locking sleeve 52 to rotate. Furthermore, the cross-sectional shape of the limiting groove 523, taken along a plane perpendicular to the axial direction, can be rectangular, annular, triangular, or other shapes. Accordingly, the cross-sectional shape of the limiting protrusion 511 matches the cross-sectional shape of the limiting groove 523. When the operator rotates the control member 51, the limiting protrusion 511 and the limiting groove 523 do not rotate relative to each other, thereby causing the locking sleeve 52 to rotate with the control member 51.

[0058] For example, Figure 7 As shown, two limiting protrusions 511 are provided, and the two limiting protrusions 511 are symmetrical about the axis of the control member 51. The axial symmetry is conducive to uniform force on the locking sleeve 52, and it is convenient for the operator to use the control member 51 to drive the locking sleeve 52 to rotate. In some embodiments of the present invention, the limiting protrusion 511 is integrally formed on the control member 51. The integral molding method facilitates the production of the control member 51. On this basis, correspondingly, two limiting grooves 523 are provided, and the two limiting grooves 523 are symmetrically arranged on both sides of the center hole 524 of the locking sleeve 52. In this embodiment, the limiting grooves 523 can be connected to the center hole 524, or they can be disconnected from the center hole 524. Figure 8As shown, the two limiting grooves 523 are both connected to the central hole 524 of the locking sleeve 52 . Such a connected arrangement facilitates the manufacture of the locking sleeve 52 .

[0059] In some embodiments of the present invention, Figure 8 and Figure 10 As shown, the depth of the limiting groove 523 is less than the length of the locking sleeve 52, and the length of the limiting protrusion 511 is less than or equal to the depth of the limiting groove 523. It can be understood that since the inner wall of the center hole 524 of the locking sleeve 52 is also provided with a second internal thread 522 for cooperating with the sliding member 30, the depth of the limiting groove 523 is less than the depth of the center hole 524, that is, less than the length of the locking sleeve 52. On this basis, the second internal thread 522 can be provided on the hole section of the center hole 524 between the bottom surface of the limiting groove 523 and the distal end surface of the locking sleeve 52. In this way, it can simultaneously ensure that the second internal thread 522 cooperates with the second external thread 301, the limiting groove 523 cooperates with the limiting protrusion 511, and the first internal thread 101 cooperates with the first external thread 521.

[0060] The following describes the overall structure of the valve clipper 100. Figure 1 and Figure 2 In this embodiment, multiple clamp arms 20 are provided. For example, if the valve clip 100 is used for mitral valve repair, the number of clamp arms 20 can be set to two. If the valve clip 100 is used for tricuspid valve repair, the number of clamp arms 2020 can be set to three. In this embodiment, the number of sliding members 30 can be set to one. The sliding member 30 is connected to the two clamp arms 20 via a pivot mechanism 40. When the sliding member 30 slides axially, the pivot mechanism 40 can drive the clamp arms 20 to rotate.

[0061] In this embodiment, the central shaft 10 is located in the middle of the valve clipper 100. The sliding member 30 is slidably disposed within the central shaft 10. A plurality of clamping arms 20 are disposed around the periphery of the central shaft 10. One end of the clamping arms 20 is rotatably connected to the central shaft 10. When the sliding member 30 and the clamping arms 20 are in interlocking motion, the clamping arms 20 can rotate about their connection with the central shaft 10. When the sliding member 30 slides distally, the clamping arms 20 rotate and expand. When the sliding member 30 slides proximally, the clamping arms 20 rotate and close. The central shaft tube 10 is set to a cylindrical structure, and the shape of the clamping arm 20 can be set to a long strip plate, for example, it can be set to an arc plate. The distal end of the clamping arm 20 is rotatably connected to the central shaft tube 10, and the inner arc surface of the clamping arm 20 faces the central shaft tube 10. When the number of clamping arms 20 is set to two, the two clamping arms 20 are symmetrically arranged on both sides of the central shaft tube 10. After the two clamping arms 20 are closed, they are in a hugging state, which is convenient for clamping the valve. An avoidance groove 201 is provided at the part near the distal end of the clamping arm 20, and two connecting ears 202 are extended from the distal end of the clamping arm 20. The two connecting ears 202 are respectively located on both sides of the avoidance groove 201, and extend to the outer wall of the central shaft tube 10 to be connected to the central shaft tube 10. For example, they can be rotatably connected by a rotating shaft.

[0062] Based on the above implementation, Figure 1 and Figure 2 As shown, the pivot mechanism 40 is connected between the sliding member 30 and the clamp arm 20. The pivot mechanism 40 drives the clamp arm 20 to rotate around the connection with the central shaft tube 10 according to the sliding of the sliding member 30. In some embodiments of the present invention, one end of the pivot mechanism 40 is fixedly connected to the sliding member 30, and the other end is rotatably connected to the clamp arm 20. For example, when the sliding member 30 slides axially toward the distal end, the pivot mechanism 40 moves toward the distal end and drives the clamp arm 20 rotatably connected thereto to rotate in a direction away from the central shaft tube 10, that is, drives the clamp arm 20 to expand; when the sliding member 30 slides axially toward the proximal end, the pivot mechanism 40 moves toward the proximal end and drives the clamp arm 20 rotatably connected thereto to rotate in a direction close to the central shaft tube 10, that is, drives the clamp arm 20 to close.

[0063] Please continue reading Figure 1 and Figure 2In some embodiments of the present invention, the pivot mechanism 40 includes a base 41 and a linkage arm 42. The base 41 is fixedly connected to the sliding member 30. For example, in some embodiments of the present invention, the sliding member 30 extends from the distal end of the central shaft 10, and the base 41 can be connected to the end of the sliding member 30, thereby expanding the range of movement of the base 41 and, in turn, the opening and closing range of the clamping arm 20. Furthermore, the linkage arm 42 in the pivot mechanism 40 is rotatably connected to the base 41 and the clamping arm 20, respectively. When the base 41 slides axially with the sliding member 30, the linkage arm 42 rotates between the base 41 and the clamping arm 20, thereby driving the clamping arm 20 to rotate. For example, the end of the linkage arm 42 away from the base 41 is rotatably connected to the middle portion of the clamping arm 20, so that when the linkage arm 42 rotates, it can apply a pulling force or a pushing force to the clamping arm 20, thereby driving the clamping arm 20 to rotate and achieve expansion or closure.

[0064] Furthermore, based on the above embodiment, Figure 1 、 Figure 3 and Figure 4 As shown, the sliding member 30 extends from the distal end of the central shaft tube 10, and the locking sleeve 52 is sleeved on the extended portion of the sliding member 30 in the initial state. Figure 2 As shown, combined Figure 5 and Figure 6 When the locking sleeve 52 is threadedly connected to the central shaft tube 10, the locking sleeve 52 is partially located in the central shaft tube 10 and maintains a threaded connection with the sliding member 30, thereby preventing the sliding member 30 from sliding axially and further preventing the clamp arm 20 from rotating.

[0065] In some embodiments of the present invention, Figure 1 and Figure 2As shown, the valve clipper 100 further includes a capture member 60, which is mounted between the central shaft 10 and the clamping arm 20. The capture member 60 is provided with barbs on the side facing the clamping arm 20 for capturing the valve. Accordingly, the valve clipper 100 further includes a control wire, such as a nylon thread, suture thread, or metal wire, connected to the capture member 60. The control wire is used to drive the capture member 60 to rotate. Thus, during the process of clamping the valve by the valve clipper 100, the valve can be first captured by the capture member 60 and then clamped by the clamping arm 20. Exemplarily, the capture member 60 can be configured as a capture spring formed from a shape memory alloy, such as a nickel-titanium alloy. The capture spring includes a plurality of springs, for example, two springs located on either side of the central shaft 10. The two springs can be configured as an integrally formed structure with a predetermined angle between them. A single control wire can be provided to simultaneously control both springs, or a plurality of control wires can be provided, each of which is connected to and controls one spring. In this embodiment, barbs are provided on the capture member 60 to facilitate the capture of the valve when the capture member 60 contacts the valve, thereby improving the accuracy of the subsequent clamping of the clamping arms 20. Furthermore, a mounting seat can be provided near the distal end of the central shaft tube 10. The mounting seat can be welded or integrally formed on the outer wall of the central shaft tube 10 to facilitate the connection of the capture member 60.

[0066] See also Figure 11 The embodiment of the second aspect of the present invention proposes a valve repair system 1000, which includes a delivery device and a valve clipper 100 according to any of the above embodiments. The delivery device is detachably connected to the valve clipper 100, and the delivery device is used to deliver the valve clipper 100 to a set position. In this embodiment, the delivery device includes a handle 710, a sheath assembly, and a connecting mechanism, wherein the sheath assembly includes a bending mechanism 730 and a plurality of sheaths 720 that are sequentially connected. The handle 710 is connected to the sheath assembly and can control part or all of the sheaths 720 in the sheath assembly to reach a set position in the patient's body. The bending mechanism 730 can control part or all of the sheaths 720 in the sheath assembly to bend at the set position. The control member 51 of the locking mechanism 50 in the valve clipper 100 can be connected to the handle 710. In the figure, it is convenient for the operator to operate the control member 51 through the handle 710; the connecting mechanism is connected to the distal end of the innermost sheath 720 and is used to be detachably connected to the valve clipper 100. Thus, when the valve clipper 100 is delivered to the set position, the valve clipper 100 adjusts its position according to the bending and movement of the sheath 720. When the valve clipper 100 clamps the valve and locks it, the connecting mechanism disengages from the valve clipper 100. After the sheath assembly is withdrawn, the valve clipper 100 remains in the patient's body.

[0067] Further, see Figure 11In some embodiments of the present invention, the delivery device includes a driving member 740, which is connected to the sliding member 30 to drive the sliding member 30 to slide. In this embodiment, the sliding member 30 is provided as one, and accordingly, the driving member 740 is also provided as one. According to the above embodiment, a channel is provided in the innermost sheath 720 of the sheath assembly, and the driving member 740 is passed through the channel. The distal end of the driving member 740 extends from the distal end of the sheath 720 and cooperates with the sliding member 30 of the valve clipper 100. Thus, the operator can pull or push the sliding member 30 by pulling or pushing the driving member 740, thereby causing the sliding member 30 to slide axially.

[0068] Taking the sliding member 30 as a sliding rod 31 as an example, Figure 11 As shown, in an optional embodiment, a blind hole is provided at one end of the slide rod 31 near the delivery device, and an internal thread is provided in the blind hole. The drive member 740 can be specifically configured as a metal wire, such as a nickel-titanium alloy wire. The drive member 740 is inserted into the cylindrical control member 51. The outer wall of the drive member 740 near the distal end is provided with an external thread that mates with the internal thread, thereby connecting the distal end of the drive member 740 to the slide member 30. The proximal end of the drive member 740 can be connected to the handle 710, and the operator can control the movement and rotation of the drive member 740 through the handle 710. It can be understood that when the slide member 30 needs to be moved axially, the operator can move the drive member 740 through the handle 710. When the delivery device needs to be separated from the valve clipper 100, the operator can rotate the drive member 740 through the handle 710 to disengage the internal and external threads, thereby withdrawing the drive member 740.

[0069] Based on the above embodiments, illustratively, the operation method of the valve repair system 1000 proposed in this embodiment is as follows: the operator operates the handle 710 to move the sheath assembly and the valve clip 100 connected to the sheath 720 according to the set steps, through the minimally invasive entrance on the body surface and the blood vessels to the set position of the mitral valve. At this time, the clamp arm 20 is in a closed state. If the locking sleeve 52 is threadedly connected to the central shaft tube 10, the operator first rotates the control member 51 to disengage the locking sleeve 52 from the central shaft tube 10, and then uses the handle 710 to push the driving member 740 to move the sliding member 30 connected thereto toward the distal end, as shown in FIG. Figure 1 As shown, the clamping arm 20 connected to the sliding member 30 via the pivot mechanism 40 is unfolded, and the position of the valve clipper 100 is adjusted to align with the portion of the mitral valve to be clipped. The driving member 740 is pulled by the handle 710 to move the sliding member 30 toward the proximal end, so that the clamping arm 20 closes and clamps the valve. Then, the control member 51 is rotated, as shown in FIG. Figure 5 and Figure 6As shown, the locking sleeve 52 is moved toward the proximal end and gradually rotated into the central shaft cylinder 10. At this time, the second internal thread 522 of the locking sleeve 52 cooperates with the second external thread 301 on the sliding member 30, and the first external thread 521 of the locking sleeve 52 cooperates with the first internal thread 101 of the central shaft cylinder 10. The sliding member 30 cannot move, that is, it is locked. Finally, the driving member 740 and the sliding member 30 are disengaged, the connecting mechanism and the valve clipper 100 are disengaged, and the driving member 740 and the sheath assembly are withdrawn, so that the valve clipper 100 remains in the patient's body in a state of clamping the valve.

[0070] The above are merely preferred embodiments of the present invention, but the scope of protection of the present invention is not limited thereto. Any changes or substitutions that can be easily conceived by a person skilled in the art within the technical scope disclosed in the present invention should be included in the scope of protection of the present invention. Therefore, the scope of protection of the present invention should be based on the scope of protection of the claims.

Claims

1. A valve clipper, characterized in that: include: A central shaft cylinder, wherein the inner wall of the central shaft cylinder is provided with a first internal thread; A plurality of clamping arms, wherein the plurality of clamping arms are arranged around the periphery of the central shaft cylinder; a sliding member, the sliding member being slidably disposed in the central shaft cylinder, the sliding member being connected to the clamping arm via a pivot mechanism so that the clamping arm rotates according to the axial sliding of the sliding member; A locking mechanism, the locking mechanism includes a control member and a locking sleeve, the locking sleeve is rotatably sleeved on the outside of the sliding member, the outer wall of the locking sleeve is provided with a first external thread for cooperating with the first internal thread, the inner wall of the locking sleeve is provided with a second internal thread, the outer wall of the sliding member is provided with a second external thread cooperating with the second internal thread, the axial length of the second external thread is greater than the axial length of the second internal thread, the control member is connected to the locking sleeve and can drive the locking sleeve to rotate, so that the locking sleeve is connected to the central shaft cylinder while remaining connected to the sliding member.

2. The valve clipper according to claim 1, characterized in that: The control member is shaped like a cylinder and is rotatably disposed between the central shaft cylinder and the sliding member. The distal end of the control member is connected to the locking sleeve.

3. The valve clipper according to claim 2, characterized in that: The proximal end portion of the locking sleeve is recessed with at least one limiting groove, and the control member is provided with a limiting protrusion, which is inserted into the limiting groove.

4. The valve clip according to claim 3, characterized in that: There are two limiting grooves, which are symmetrically arranged on both sides of the central hole of the locking sleeve and are respectively communicated with the central hole.

5. The valve clipper according to claim 4, characterized in that: The depth of the limiting groove is smaller than the length of the locking sleeve, and the second internal thread is provided on a hole section of the central hole between the bottom surface of the limiting groove and the distal end surface of the locking sleeve.

6. The valve clip according to claim 4, characterized in that: Two limiting protrusions are provided, and the two limiting protrusions are symmetrical about the axis of the control member.

7. The valve clip according to claim 6, characterized in that: The control member is configured as a shape memory alloy tube, and / or the limiting protrusion is integrally formed on the control member.

8. The valve clip according to any one of claims 1 to 7, characterized in that: The pivot mechanism includes a base and a linkage arm, the linkage arm is rotatably connected to the base and the clamping arm respectively, and the base is fixedly connected to the sliding member.

9. A valve repair system, characterized in that: The valve repair system comprises: A valve clipper, wherein the valve clipper is the valve clipper according to any one of claims 1 to 8; A delivery device is detachably connected to the valve clip to deliver the valve clip to a set position. The delivery device includes a driving member connected to a sliding member of the valve clip to drive the sliding member to slide.

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