Bead Removing Device, Test Cup Transportation System and Method for Removing Magnetic Beads from Test Cups

Abstract

A bead removing device, a test cup transportation system and a method for removing magnetic beads from a test cup, comprising a bracket (20), a test cup table (10) mounted on the bracket (20), and a bead removing mechanism (100) mounted on the bracket (20). The test cup table (10) is provided with a placement seat (11) for placing a test cup (500), and the bead removing mechanism (100) is used to remove the magnetic beads in the test cup (500) on the placement seat (11). The controller can generate a bead removing operation instruction or a bead retaining operation instruction according to the test items input by the user and the test methods corresponding to the test items, which is simple to operate and can reduce the test cost at the same time.

Description

Technical Field

[0001] The present application relates to the technical field of medical devices, and in particular, to a bead removing device, a test cup transportation system, and a method for removing magnetic beads from a test cup. Background Art

[0002] Currently, the detection methods of coagulation analyzers on the market are divided into two types: one is the magnetic bead method, which uses the electrical signal generated by the cutting of magnetic force lines during the swinging of magnetic beads to monitor the swinging amplitude of the magnetic beads, and determines the coagulation point when the swinging amplitude of the magnetic beads decays to 50%; the other detection method is the optical method, and the optical coagulometer measures the coagulation function according to the change in turbidity during the plasma coagulation process.

[0003] In order to be compatible with both the magnetic bead method and the optical method, the test cups in the existing cup tray assembly basically encapsulate a magnetic bead. However, when using such a cup with a magnetic bead for optical method testing, since the position of the magnetic bead will cause great interference to the results of the optical method measurement, it is often necessary to raise the optical axis to the best measurement area above the magnetic bead, so more samples and reagents need to be added, resulting in waste of reagents and increased test costs. Summary of the Invention

[0004] The present application provides a bead removing device, a test cup transportation system, and a method for removing magnetic beads from a test cup, which can quickly remove the magnetic beads in the test cup according to the test requirements and reduce the test cost.

[0005] According to the first aspect of the embodiments of the present application, a bead removing device is provided, including a bracket, a test cup table, and a bead removing mechanism. The test cup table and the bead removing mechanism are both installed on the bracket. The test cup table is provided with a placement seat for placing a test cup; the bead removing mechanism is used to remove the magnetic bead in the test cup on the placement seat.

[0006] According to the second aspect of the embodiments of the present application, a test cup transportation system is provided, including a cup inlet slot, a bead removing device, and a test cup transfer mechanism. The cup inlet slot includes a loading position and an unloading position. The loading position corresponds to a loading device to receive the test cup with a magnetic bead conveyed by the loading device. The test cup in the cup inlet slot is unloaded through the unloading position; the bead removing device includes a bracket, a test cup table, and a bead removing mechanism. The test cup table is installed on the bracket. The test cup table is provided with a placement seat for placing a test cup. The bead removing mechanism is installed on the bracket and is used to remove the magnetic bead in the test cup on the placement seat. The bracket is movably installed at the unloading position of the cup inlet slot, and the placement seat corresponds to the loading position of the cup inlet slot so that the test cup can enter the placement seat; the test cup transfer mechanism is used to transfer the test cup on the placement seat to the next process.

[0007] According to the third aspect of the embodiments of the present application, a method for removing magnetic beads from a test cup is provided, including:

[0008] The controller obtains the test items and test methods applicable to the current test cup according to the predetermined test items and the corresponding test methods for the test items. If the test method for the test items corresponding to the current test cup is not the magnetic bead test method, a bead removal operation instruction is output.

[0009] The bead removal mechanism is connected to the operation instruction output end of the controller. When the bead removal mechanism receives the bead removal operation instruction, it removes the magnetic beads from the test cup placed on the placement seat in the test cup table.

[0010] The technical solution provided by the embodiment of the present application may include the following beneficial effects: The present application designs a bead removal device, a test cup transportation system, and a method for removing magnetic beads from a test cup, including a bracket, a test cup table, and a bead removal mechanism. The test cup table is provided with a placement seat for placing the test cup, and the bead removal mechanism is used to remove the magnetic beads from the test cup on the placement seat. In this way, the magnetic beads in the test cup can be removed according to the test requirements, avoiding interference caused by the magnetic beads in the optical measurement method, reducing reagent waste, and lowering the test cost.

[0011] It should be understood that the above general description and the following detailed description are only exemplary and explanatory, and cannot limit the present application. BRIEF DESCRIPTION OF THE DRAWINGS

[0012] In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings required for the description of the embodiments will be briefly introduced below. Obviously, the drawings in the following description are some embodiments of the present application. For those of ordinary skill in the art, other drawings can be obtained based on these drawings without creative efforts.

[0013] Figure 1 is a schematic structural diagram of a test cup transportation system provided by an embodiment of the present application;

[0014] Figure 2 is Figure 1 another state structural diagram of the test cup transportation system in;

[0015] Figure 3 is Figure 1 a partial exploded view of the test cup transportation system in;

[0016] Figure 4 is Figure 1 a schematic structural diagram of the test cup placed in the bead removal device in;

[0017] Figure 5 is Figure 1 another state structural diagram of the test cup placed in the bead removal device in;

[0018] Figure 6 isFigure 1 Schematic structural diagram of the bead removing device in

[0019] Figure 7 is Figure 1 Exploded schematic diagram of the bead removing device in

[0020] Figure 8 is Figure 1 Schematic structural diagram of the bracket in

[0021] Figure 9 is Figure 1 Another state schematic structural diagram of the bracket in

[0022] Figure 10 is Figure 1 Another state schematic structural diagram of the bracket in

[0023] Figure 11 is Figure 1 Schematic structural diagram of the bead removing mechanism in

[0024] Figure 12 is Figure 1 Another state schematic structural diagram of the bead removing mechanism in

[0025] Figure 13 is Figure 1 Another state schematic structural diagram of the bead removing mechanism in

[0026] Figure 14 Schematic structural diagram of a test cup transportation system provided by another embodiment of the present application;

[0027] Figure 15 is Figure 14 Another state schematic structural diagram of the test cup transportation system in

[0028] Explanation of reference numerals:

[0029] 100, bead removing device;

[0030] 10, test cup table; 11, placing seat; 111, placing groove; 112, bevel chamfer; 12, rotating table; 121, limiting lug; 122, notch; 13, connecting shaft; 131, connecting shaft through groove; 20, bracket; 21, fixed bracket; 211, connecting shaft perforation; 22, bracket body; 221, connecting shaft through hole; 222, bead discharging guide groove; 2221, left side plate; 2222, right side plate; 2223, front baffle; 223, test cup table rotating groove; 224, limiting card slot; 2241, second limiting member; 2242, first limiting member; 30, bead removing mechanism; 31, driving member; 311, output shaft; 32, driving assembly; 33, magnetic rod; 34, transverse driving motor; 341, lead screw assembly;

[0031] 200, Cup Feeding Groove; 201, Loading Position; 202, Unloading Position; 2021, Slide Rail Assembly;

[0032] 300, Test Cup Transfer Mechanism;

[0033] 400, Loading Device;

[0034] 500, Test Cup. Detailed Embodiment

[0035] Next, the technical solutions in the embodiments of the present application will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present application. Obviously, the described embodiments are part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present application.

[0036] The flowcharts shown in the accompanying drawings are only illustrative examples, and do not necessarily include all contents and operations / steps, nor do they necessarily need to be executed in the described order. For example, some operations / steps can also be decomposed, combined, or partially merged. Therefore, the actual execution order may be changed according to the actual situation.

[0037] Next, some embodiments of the present application will be described in detail in conjunction with the accompanying drawings. Without conflict, the following embodiments and the features in the embodiments can be combined with each other.

[0038] As Figures 1 to 4 shown, the present application discloses a test cup transportation system, which is applied to the coagulation analysis detection project. Specifically, the test cup transportation system of the present application includes a bead removal device 100, a cup feeding groove 200, and a test cup transfer mechanism 300. The cup feeding groove 200 includes a loading position 201 and an unloading position 202. Among them, the loading position 201 corresponds to the loading device 400 to receive the test cup 500 with magnetic beads transported by the loading device 400, and the test cup 500 in the cup feeding groove 200 is unloaded through the unloading position 202. In this embodiment, the bead removal device 100 includes a test cup table 10, a bracket 20, and a bead removal mechanism 30. The test cup table 10 is installed on the bracket 20. The test cup table 10 is provided with a placement seat 11 for placing the test cup 500. The bead removal mechanism 30 is installed on the bracket 20 and is used to remove the magnetic beads in the test cup 500 on the placement seat 11. In addition, the bracket 20 is movably installed on the unloading position 202 of the cup feeding groove 200, and the position of the placement seat 11 corresponds to the position of the loading position 201, so that the test cup 500 can enter the placement seat 11; the test cup transfer mechanism 300 is used to transfer the test cup 500 on the placement seat 11 to the next process.

[0039] When the test cup transportation system receives a predetermined test item and the corresponding test method for the test item, the loading position 201 transports the test cup 500 with magnetic beads on the loading device 400 to the placement seat 11. The bead removal mechanism 30 selects whether bead removal is required according to the corresponding test method for the test item. For example, when the test method is the magnetic bead method, the bead removal mechanism 30 retains the magnetic beads in the test cup 500 and does not perform any operation on the magnetic beads in the test cup 500. Then, the bead removal device 100 is moved to the unloading position 202, and the test cup 500 on the placement seat 11 is transferred to the next process through the test cup transfer mechanism 300. When the test method is the optical method, after the bead removal mechanism 30 removes the magnetic beads in the test cup 500, the bead removal device 100 is moved to the unloading position 202, and the test cup 500 on the placement seat 11 is transferred to the next process through the test cup transfer mechanism 300.

[0040] After adopting the above technical solution, since the traditional test cup is sealed in the cup tray assembly, in order to be compatible with both the magnetic bead method and the optical method, the test cup in the cup tray assembly basically contains a magnetic bead. However, in this application, the magnetic bead in the cup tray assembly can be removed or retained according to the requirements of the test item, which not only does not affect the test results of the reagent, but also does not cause reagent waste and increase the test cost.

[0041] Among them, the bead removal mechanism 30 in the bead removal device 100 can include any bead removal method. For example, the test cup table 10 is driven to rotate by a rotary cylinder so that the magnetic beads slide out from the cup mouth of the test cup; or the magnetic beads in the test cup are taken out by using a jaw; even the magnetic beads in the test cup can be directly sucked and taken out by using a vacuum chuck, or a magnetic rod is used to suck the magnetic beads in the test cup by magnetic force to remove the magnetic beads, etc. The main purpose is to take out the magnetic beads in the test cup, and at the same time, the test cup is moved to the next process through the cup inlet groove 200 for reagent addition. This application does not make any restrictions.

[0042] The technical solution of the bead removal mechanism 30 in this application will be introduced in detail below with specific embodiments.

[0043] Embodiment 1 is as Figures 4 to 13 shown. A bead removal device 100 in this embodiment includes a test cup table 10, a bracket 20, and a bead removal mechanism 30. Among them, the test cup table 10 and the bead removal mechanism 30 are both installed on the bracket 20, and a placement seat 11 for placing the test cup 500 is provided on the test cup table 10. The bead removal mechanism 30 is used to remove the magnetic beads in the test cup 500 on the placement seat 11.

[0044] After adopting the above technical solution, when optical method detection is required, the test cup 500 is placed in the placement seat 11, and the bead removal mechanism 30 is used to remove the magnetic beads in the test cup 500, thereby avoiding interference of the position where the magnetic beads are located on the measurement results, and at the same time, there is no need to add more samples and reagents, resulting in reagent waste and increasing the test cost.

[0045] It should be noted that the bead removal mechanism 30 can be embedded in the test cup transportation system and used in series with the test cup transportation system. A buffer position for storing the bead removal mechanism 30 can also be set separately. The bead removal mechanism 30 placed at the buffer position performs a removal operation on the test cup with magnetic beads, waiting for the test cup transfer device to transfer the test cup to the next process. Intelligent control can be performed in the bead removal mechanism 30 so that the bead removal device 100 can determine whether it is necessary to remove the magnetic beads in the test cup according to the specific project, thereby improving the test speed of the reagent.

[0046] In an alternative embodiment, as Figures 4 to 7 shown, the test cup table 10 is rotatably mounted on the bracket 20. Specifically, the bead removal mechanism 30 includes a driving member 31. The output shaft 311 of the driving member 31 is in transmission connection with the test cup table 10 for driving the test cup table 10 to rotate, so that the test cup 500 on the placement seat 11 of the test cup table 10 can rotate relative to the bracket 20 in the vertical plane under the output power of the driving member 31.

[0047] Specifically, when the test cup 500 is placed on the placement seat 11, the driving member 31 is in an initial state, and at this time, the mouth of the test cup 500 faces upward; if the bead removal device 100 is placed flat on the placement surface, the end face of the mouth of the test cup 500 is just parallel to the horizontal line (as Figure 4 ); when it is necessary to remove the magnetic beads in the test cup 500 placed on the placement seat 11, the driving member 31 is started and drives the test cup table 10 to rotate, and the test cup 500 rotates together with the test cup table 10 (as Figure 5 ). When the test cup table 10 rotates to a preset angle, the magnetic beads in the test cup 500 can just slide out along the wall of the test cup 500, thus completing the entire bead removal process of the test cup 500.

[0048] In an alternative embodiment, as Figure 7 、 Figure 12 and Figure 13 shown, the driving member 31 is an electric motor. The test cup table 10 is provided with a connecting shaft 13 on the side opposite to the placement seat 11. The end of the output shaft 311 of the driving member 31 is connected to the connecting shaft 13. Specifically, a connecting shaft through groove 131 is opened at the end of the connecting shaft 13. The connecting shaft through groove 131 is located in the middle of the end face of the end of the connecting shaft 13, and the shape and size of the connecting shaft through groove 131 are adapted to the shape and size of the output shaft 311. In order to enable the driving member 31 to better transmit the torque through the output shaft 311 to the placement seat 11, a fastening screw hole penetrating through the connecting shaft through groove 131 can be opened on the connecting shaft 13, and then the connecting shaft 13 is locked in the connecting shaft through groove 131 by a fastening screw.

[0049] In an alternative embodiment, as Figure 2 、 Figures 7 to 13As shown in the figure, the bracket 20 includes a bracket body 22 and a fixed bracket 21. Among them, the fixed bracket 21 has an L-shaped structure. Its vertical end is connected to the bracket body 22, and the horizontal end is installed at the unloading position 202 of the cup inlet groove 200 through the slide rail assembly 2021. The slide rail assembly 2021 extends from the unloading position 202 of the cup inlet groove 200 to the test cup transfer mechanism 300. The bead removal device receives the test cup in the cup inlet groove 200 and performs bead removal operations. The slide rail assembly drives the bead removal device to move from the unloading position of the cup inlet groove 200 to the test cup transfer mechanism 300. The test cup transfer mechanism 300 takes out the test cup in the bead removal device and transfers it to the next process. The test cup transfer mechanism 300 can be a mechanical gripper, etc.

[0050] In this embodiment, a connecting shaft through hole 221 is provided on the bracket body 22, and a connecting shaft through hole 211 is provided on the fixed bracket 21. When the driving member 31 is installed on the bracket body 22, the output shaft 311 sequentially passes through the connecting shaft through hole 211 and the connecting shaft through hole 221 and then is connected to the connecting shaft through groove 131. In addition, in order to improve the load-bearing capacity of the output shaft 311 in the radial direction, a bearing can be sleeved on the output shaft 311, so that the inner ring of the bearing is connected to the output shaft 311, and the outer ring of the bearing is fixed on the connecting shaft through hole 221.

[0051] In an alternative embodiment, as Figures 6 to 8 shown, a test cup table rotation groove 223 for accommodating the test cup table 10 is further provided on the bracket 20. The test cup table rotation groove 223 is adapted to the test cup table 10. The test cup table 10 is placed in the test cup table rotation groove 223 and is rotatably connected to the test cup table rotation groove 223 through a connecting shaft. Specifically, a connecting shaft through hole 221 for the connecting shaft to penetrate is provided at the bottom of the test cup table rotation groove 223. The test cup table 10 is fitted in the test cup table rotation groove 223, and the test cup table 10 is rotatably installed in the test cup table rotation groove 223 through a connecting shaft. After adopting the above technical solutions, not only can the structure of the entire bead removal device 100 be made more compact, but also the load-bearing capacity of the test cup table 10 can be improved.

[0052] In an alternative embodiment, as Figures 4 to 8 shown, the bead removal device 100 further includes a limiting mechanism for limiting the rotation angle of the test cup table 10. Specifically, the limiting mechanism can be a control member installed on the driving member 31 to control the rotation angle of the output shaft 311; or the limiting mechanism can be a boss or a chute provided in the connecting shaft through hole 221, and a chute or a boss provided on the output shaft 311 that matches the boss or the chute, etc. Its main purpose is to control the rotation angle of the test cup table 10 to prevent the test cup 500 from falling off the test cup table 10. At the same time, it can ensure that after the magnetic beads in the test cup table 10 are removed, the test cup table 10 can drive the test cup 500 to return to the initial state where the test cup 500 is placed on the test cup table 10.

[0053] In this embodiment, as Figures 7 to 12 shown, the limiting mechanism includes: a limiting lug 121 provided on the outer side of the test cup table, a first limiting member 2242 and a second limiting member 2241 provided in the test cup table rotation groove 223 of the bracket 20. Among them, the central angle corresponding to the stroke ranges of the first limiting member 2242 and the second limiting member 2241 is 100 to 150 degrees. It should be noted that the first limiting member 2242 and the second limiting member 2241 can be components such as bosses provided on the bracket to limit the movement of the limiting lug 121. Specifically, a limiting card slot 224 is provided on the groove wall of the test cup table rotation groove 223. The first end wall of the limiting card slot 224 serves as the first limiting member 2242, and the second end wall of the limiting card slot 224 opposite to the first end wall serves as the second limiting member 2241. The limiting lug 121 moves between the first end wall and the second end wall. The central angle corresponding to the stroke between the first limiting member 2242 and the second limiting member 2241 of the limiting card slot 224 is 100 to 150 degrees. When the limiting lug 121 of the test cup table 10 is located at the first limiting member 2242 of the limiting card slot 224, the end face of the placing seat 11 is parallel to the horizontal line, that is, the test cup of the test cup 500 is parallel to the horizontal line. When the limiting lug 121 of the test cup table 10 rotates to the second limiting member 2241 of the limiting card slot 224, the test cup 500 on the placing seat 11 is tilted, so that the magnetic beads in the test cup 500 can slide out along the cup wall.

[0054] In an alternative embodiment, as Figures 7 to 11 shown, the test cup table 10 includes a rotating table 12 in the shape of a frustum of a cone. Among them, the placing seat 11 is arranged in the middle of the rotating table 12, and a notch 122 is provided on the upper side of the rotating table 12. The end face formed by the notch 122 is flush with the upper end face of the placing seat 11. Specifically, the length and width of the rotating table 12 are slightly larger than the length and width of the test cup. A notch 122 is provided on the rotating table 12, which not only facilitates the integral molding of the placing seat 11 and the rotating table 12, but also facilitates the molding process of the limiting lug 121. For example, with the end face of the notch 122 as the reference, the limiting lug 121 is provided at a position at a preset distance from the end face of the notch 122. This preset distance just enables the rotating table 12 to rotate to a certain angle, that is, when the limiting lug 121 contacts the second limiting member 2241, the magnetic beads in the test cup on the placing seat 11 can slide out along the cup wall of the test cup without causing the test cup to slide out of the placing seat 11.

[0055] In an alternative embodiment, as Figure 11As shown, a placement groove 111 is provided on the placement seat 11, and the width of the placement groove 111 is adapted to the width of the test cup, and the inner sides of both sides of the placement groove 111 and the upper ends of both sides are provided with chamfers 112, so that not only can the test cup quickly enter the placement groove 111 through the chamfers 112, but also the relative position of the test cup and the placement groove 111 can be ensured.

[0056] In an optional embodiment, if Figures 4 to 10 As shown, the support body 22 is also provided with a bead guide groove 222, which is located on one side of the placement seat 11 and is used to guide the magnetic beads taken out of the test cup to smoothly enter the magnetic bead storage device. Specifically, the bead guide groove 222 is located on the lower left side of the test cup rotating groove 223 (as shown in FIG. Figure 10 ), the limit slot 224 is provided on the upper right side of the rotating slot 223 of the test cup table, so that the limited space of the support body 22 can be fully utilized while ensuring the hardness of the support body 22. In addition, it is ensured that the magnetic beads can fall into the bead discharge guide slot 222 for the collection of the magnetic beads, for example, a magnetic bead storage device is provided below the bead discharge guide slot 222.

[0057] In an optional embodiment, the bead discharge guide groove 222 is in an inwardly concave arc shape toward the placement seat 11, and the center of the bead discharge guide groove 222 coincides with the axis of rotation of the test cup stage 10. Specifically, the inwardly concave diameter of the bead discharge guide groove 222 is substantially equal to the diameter formed by the rotation track of the outermost edge of the test cup, wherein the test cup is placed on the placement groove 111 and rotates with the test cup stage 10; or the inwardly concave diameter of the bead discharge guide groove 222 is slightly larger than the diameter of the arc of the outermost edge of the test cup rotating with the test cup stage 10, which can not only prevent the test cup from colliding with the outer wall of the bead discharge guide groove 222 during the rotation process, but also make the outermost edge of the test cup rotate in contact with the inwardly concave edge of the bead discharge guide groove 222, thereby preventing the test cup from leaving the placement groove 111.

[0058] In an optional embodiment, if Figure 9 The bead guide groove 222 is provided with a front baffle 2223 and two side baffles, the two side baffles are respectively located on both sides of the bead guide groove 222, the front baffle 2223 is connected to the front ends of the two side baffles, and the notch of the bead guide groove 222 corresponds to the cup mouth after the test cup is rotated by the placement seat. Specifically, the two side baffles are a left side plate 2221 and a right side plate 2222, wherein the left side plate 2221 is arranged on the left side of the bead guide groove 222, and the right side plate 2222 is arranged on the right side of the bead guide groove 222, and the front baffle 2223 is connected to the left side plate 2221 and the right side plate 2222, so that the bead guide groove 222 forms a closed groove body with two ends being open, which plays a role in guiding magnetic beads.

[0059] Example 2 Figure 14As shown in the figure, the difference between this embodiment and the first embodiment lies in the bead removing mechanism 30, and the rest is substantially the same. For example, the placing base 11 can be directly fixed on the bracket. The bead removing mechanism 30 of this embodiment includes a magnetic rod 33 and a driving assembly 32. Among them, the driving assembly 32 drives the magnetic rod 33 into the test cup 500 on the placing base 11 and takes out the magnetic beads in the test cup 500. The structure is simple but practical.

[0060] Specifically, the bead removing mechanism 30 includes a lateral driving motor 34. The lateral driving motor 34 drives the magnetic rod 33 to move laterally through a lead screw assembly 341. When the driving assembly 32 drives the magnetic rod 33 to move towards the test cup 500 and makes the magnetic rod 33 suck the magnetic beads in the test cup 500, then the driving assembly 32 drives the magnetic rod 33 to move in the direction opposite to the test cup 500. Finally, after the lateral driving motor 34 drives the magnetic rod 33 away from the test cup 500 in the lateral direction, the magnetic beads are stored in the magnetic bead storage device.

[0061] In an alternative embodiment, as Figure 11 shown, the placing base 11 is provided with a placing groove 111. The width of the placing groove 111 is adapted to the width of the test cup, and inclined chamfers 112 are provided on the inner sides of both sides and the upper ends of both sides of the placing groove 111. This can not only enable the test cup to quickly enter the placing groove 111 through the inclined chamfers 112, but also ensure the relative position between the test cup and the placing groove 111.

[0062] As Figures 1 to 14 shown, the present application also provides a method for removing magnetic beads from a test cup, including:

[0063] The controller obtains the test item and the corresponding test method applied to the current test cup according to the predetermined test item and the corresponding test method of the test item. If the test method corresponding to the test item of the current test cup is not the magnetic bead test method, an instruction for bead removal operation is output;

[0064] The bead removing mechanism 30 is connected to the operation instruction output end of the controller. When the bead removing mechanism 30 receives the bead removal operation instruction, the magnetic beads in the test cup on the placing base 11 in the test cup table 10 are taken out.

[0065] In the first embodiment, since the bead removing mechanism 30 includes a driving member 31, and the driving member 31 is an electric motor, the controller can be one of the currently common controllers such as a PLC controller, a DSP controller, and a single-chip microcomputer controller. Specifically, after the test cup transportation system is started, the controller continuously reads the test item input by the user and the corresponding test method of the test item, and outputs corresponding instructions according to the test item and the corresponding test method of the test item. Among them, the test item includes a coagulation analysis test item, and the corresponding test method of the test item can be the magnetic bead method or the optical method. The user can select different test methods according to needs.

[0066] Specifically, when the controller receives that the test method corresponding to the test item is the optical method, the controller generates a bead-removing operation instruction and sends the bead-removing operation instruction to the bead-removing mechanism 30. When the bead-removing mechanism 30 receives the bead-removing operation instruction, the driving member 31 in the bead-removing mechanism 30 starts and drives the test cup table 10 to rotate, and the test cup 500 rotates together with the test cup table 10 (as Figure 5 ), when the test cup table 10 rotates to a preset angle, the magnetic beads in the test cup 500 slide out along the inner wall of the test cup 500, and then the driving member 31 drives the test cup table 10 to rotate in the opposite direction for resetting. After the bead-removing mechanism 30 completes the entire bead-removing process, the bead-removing device 100 moves to the unloading position 202, and the test cup transfer mechanism 300 transfers the test cup 500 on the placement seat 11 to the next process, where the next process includes the addition of reagents.

[0067] In an alternative embodiment, the controller obtains the test item and test method applied to the current test cup 500 according to the predetermined test item and the corresponding test method of the test item. If the test method corresponding to the current test cup 500 is the magnetic bead test method, a bead-retaining operation instruction is output; when the bead-removing mechanism 30 receives the bead-retaining operation instruction, no operation is performed to remove the magnetic beads in the test cup 500 on the placement seat 11 in the test cup table 10. It should be noted that in addition to obtaining the test item and test method applied to the current test cup according to the preset rules, the controller can also receive a request instruction input by the user and generate a corresponding operation instruction according to the request instruction input by the user to control the operation of the bead-removing mechanism 30.

[0068] Specifically, when the controller receives that the test method corresponding to the test item is the magnetic bead method, the controller generates a bead-retaining operation instruction and sends the bead-retaining operation instruction to the bead-removing mechanism 30. When the bead-removing mechanism 30 receives the bead-retaining operation instruction, the feeding device 400 transports the test cup 500 with magnetic beads to the placement seat 11 through the feeding position 201. The bead-removing device 100 does not perform any operation on the test cup 500 and directly moves to the unloading position 202. The test cup transfer mechanism 300 transfers the test cup 500 on the placement seat 11 to the next process, where the next process includes the addition of reagents.

[0069] In the first embodiment, when the bead-removing mechanism 30 receives the bead-removing operation instruction, the driving member 31 of the bead-removing mechanism 30 drives the test cup table 10 to rotate and causes the test cup to tilt, so that the magnetic beads in the test cup 500 roll out. In the second embodiment, when the bead-removing mechanism 30 receives the bead-removing operation instruction, the driving assembly 32 of the bead-removing mechanism 30 drives the magnetic rod 33 to approach the test cup table 10 and extend into the test cup 500, so that the magnetic beads in the test cup 500 are attracted by the magnetic rod 33, and the driving assembly 32 drives the magnetic rod 33 away from the test cup table 10, thereby completing the bead-removing operation.

[0070] After adopting the above technical solution, since the existing test cups are stored in the cup tray assembly and the test cups are provided with magnetic beads, this not only causes interference to the optical measurement method, but also correspondingly increases the test cost. In this application, the cup tray assembly can be directly placed on the feeding device 400, and the controller can generate a bead removal operation instruction or a bead retention operation instruction according to the test items input by the user and the test methods corresponding to the test items. The operation is simple and the test cost can be reduced at the same time.

[0071] As described above, the above are only specific embodiments of the present application, but the protection scope of the present application is not limited thereto. Any person skilled in the art within the technical scope disclosed in the present application can easily think of various equivalent modifications or substitutions, and these modifications or substitutions should all be covered within the protection scope of the present application. Therefore, the protection scope of the present application should be subject to the protection scope of the claims.

Claims

1. A bead removing device, characterized in that, Comprising: A bracket; A test cup platform, mounted on the bracket, and the test cup platform is provided with a placement seat for placing a test cup; A bead removing mechanism, mounted on the bracket, for removing magnetic beads from the test cup on the placement seat; The test cup platform is rotatably mounted on the bracket, and the bead removing mechanism includes: A driving member, the output shaft of the driving member is in transmission connection with the test cup platform, and is used to drive the test cup platform to rotate, so that the test cup on the placement seat of the test cup platform can rotate relative to the bracket in a vertical plane under the output power of the driving member.

2. The bead removing device according to claim 1, characterized in that, The driving member is an electric motor, the test cup platform is provided with a connecting shaft on the side opposite to the placement seat, the end of the output shaft of the electric motor is connected to the connecting shaft, and the bracket is provided with a connecting shaft through hole, and the connecting shaft is inserted into the connecting shaft through hole.

3. The bead removing device according to claim 2, characterized in that, The bracket is further provided with a test cup platform rotating groove for accommodating the test cup platform, the test cup platform rotating groove is adapted to the test cup platform, the test cup platform is placed in the test cup platform rotating groove, and is rotatably connected to the test cup platform rotating groove through a connecting shaft.

4. The bead removing device according to claim 1, characterized in that, The bead removing device further includes a limiting mechanism for limiting the rotation angle of the test cup platform.

5. The bead removing device according to claim 3, characterized in that, The bead removing device further includes a limiting mechanism for limiting the rotation angle of the test cup platform. The limiting mechanism includes: a limiting lug provided on the outer side of the test cup platform, a first limiting member and a second limiting member provided in the test cup platform rotating groove of the bracket, and the first limiting member and the second limiting member are used to limit the movement of the limiting lug; wherein, the central angle corresponding to the movement stroke range of the limiting lug between the first limiting member and the second limiting member is 100-150 degrees.

6. The bead removing device according to claim 5, characterized in that, The groove wall of the test cup platform rotating groove is provided with a limiting card slot, the first end wall of the limiting card slot serves as the first limiting member, and the second end wall of the limiting card slot opposite to the first end wall serves as the second limiting member, and the limiting lug moves between the first end wall and the second end wall.

7. The bead removing device according to claim 1, characterized in that, The test cup platform includes a rotating platform in the shape of a frustum of a cone, the placement seat is arranged in the middle of the rotating platform, a notch is provided on the upper side of the rotating platform, and the end face formed by the notch is flush with the upper end face of the placement seat; or The placement seat is provided with a placement groove, the width of the placement groove is adapted to the width of the test cup, and the placement groove is provided with a chamfered slope so that the test cup can enter the placement groove through the chamfered slope.

8. The bead removing device according to claim 1, characterized in that, The bracket is further provided with a bead discharging guide groove, and the end of the bead discharging guide groove corresponds to the bead inlet of the magnetic bead storage device to guide the magnetic beads to roll to the magnetic bead storage device.

9. The bead removing device according to claim 8, characterized in that, The bead discharging guide groove is concave in an arc shape towards the direction of the placement seat, and the center of the arc of the bead discharging guide groove coincides with the axis of rotation of the test cup platform.

10. The bead removing device according to claim 8 or 9, characterized in that, The bead discharging guide groove is provided with a front baffle and two side baffles, the two side baffles are respectively located on both sides of the bead discharging guide groove, and the front baffle is connected to the front ends of the two side baffles and makes the notch of the bead discharging guide groove correspond to the cup mouth of the test cup after rotation through the placement seat.

11. A test cup transportation system, characterized in that, Comprising: The cup feeding trough includes a loading position and an unloading position. The loading position corresponds to the loading device to receive the test cups with magnetic beads conveyed by the loading device. The test cups in the cup feeding trough are unloaded through the unloading position. The bead removing device includes a bracket, a test cup table and a bead removing mechanism. The test cup table is installed on the bracket. The test cup table is provided with a placement seat for placing the test cup. The bead removing mechanism is installed on the bracket and is used to take out the magnetic beads in the test cup on the placement seat. The bracket is movably installed at the unloading position of the cup feeding trough, and the placement seat corresponds to the loading position of the cup feeding trough so that the test cup can enter the placement seat. The test cup transfer mechanism transfers the test cup on the placement seat to the next process.

12. The test cup transportation system according to claim 11, characterized in that, The test cup table is rotatably installed on the bracket, and the test cup on the placement seat of the test cup table rotates relative to the bracket in the vertical plane. The bead removing mechanism includes a driving member, and the output shaft of the driving member is in transmission connection with the test cup table to drive the test cup to rotate.

13. The test cup transportation system according to claim 12, characterized in that, The driving member is an electric motor. The test cup table is provided with a connecting shaft on the side opposite to the placement seat. The bracket is provided with a connecting shaft through hole, and the connecting shaft passes through the connecting shaft through hole and is connected to the output shaft of the electric motor.

14. The test cup transportation system according to claim 13, characterized in that, The bracket is further provided with a test cup table rotation groove for accommodating the test cup table. The test cup table rotation groove is adapted to the test cup table. The test cup table is placed in the test cup table rotation groove and is rotatably connected to the test cup table rotation groove through the connecting shaft.

15. The test cup transportation system according to claim 12, characterized in that, The bead removing device further includes a limiting mechanism for limiting the rotation angle of the test cup table.

16. The test cup transportation system according to claim 14, characterized in that The bead removing device further includes a limiting mechanism for limiting the rotation angle of the test cup table. The limiting mechanism includes: a limiting lug provided on the outer side of the test cup table, a first limiting member and a second limiting member provided in the test cup table rotation groove of the bracket, and the first limiting member and the second limiting member are used to limit the movement of the limiting lug; wherein, the central angle corresponding to the movement stroke range of the limiting lug between the first limiting member and the second limiting member is 100-150 degrees.

17. The test cup transportation system according to claim 16, characterized in that The groove wall of the test cup table rotation groove is provided with a limiting card slot. The first end wall of the limiting card slot serves as the first limiting member, and the second end wall of the limiting card slot opposite to the first end wall serves as the second limiting member. The limiting lug moves between the first end wall and the second end wall.

18. The test cup transportation system according to claim 11, characterized in that The test cup table includes a rotating table in the shape of a frustum of a cone. The placement seat is arranged in the middle of the rotating table. A notch is provided on the upper side of the rotating table, and the end surface formed by the notch is flush with the upper end surface of the placement seat.

19. The test cup transportation system according to claim 11, characterized in that The bracket is further provided with a bead discharging guide groove. The bead discharging guide groove is located on one side of the placement seat. The bead discharging guide groove is concave in an arc shape towards the placement seat and is used to collect the magnetic beads taken out from the test cup.

20. The test cup transportation system according to claim 11, characterized in that The bead removing mechanism includes a magnetic rod and a driving assembly. The driving assembly drives the magnetic rod into the test cup on the placement seat and takes out the magnetic beads in the test cup.

21. A method for removing magnetic beads from a test cup, wherein the test cup contains magnetic beads, characterized in that Including: The controller obtains the test items and test methods applicable to the current test cup according to the predetermined test items and the corresponding test methods for the test items. If the test method for the test item corresponding to the current test cup is not the magnetic bead test method, a bead removal operation instruction is output. The bead removal mechanism is connected to the operation instruction output end of the controller. When the bead removal mechanism receives the bead removal operation instruction, the magnetic beads in the test cup placed on the placement seat in the test cup table are taken out.

22. The method for removing magnetic beads according to claim 21, characterized in that It also includes: The controller obtains the test items and test methods applicable to the current test cup according to the predetermined test items and the corresponding test methods for the test items. If the test method for the test item corresponding to the current test cup is the magnetic bead test method, a bead retention operation instruction is output. When the bead removal mechanism receives the bead retention operation instruction, it does not perform the operation of taking out the magnetic beads in the test cup placed on the placement seat in the test cup table.

23. The method for removing magnetic beads according to claim 21, characterized in that When the bead removal mechanism receives the bead removal operation instruction, the driving member of the bead removal mechanism drives the test cup table to rotate and the test cup to tilt, so that the magnetic beads in the test cup roll out.

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