A classification management system for bone marrow cells

Abstract

The present invention relates to a classification management system for bone marrow cells, comprising: a user interaction interface, which is used for users to perform specific operations on the bone marrow cell classification management system, input the bone marrow cell types and corresponding bone marrow cell images into the system and classify and archive them; a digital acquisition control system, which is used to acquire digital images of bone marrow smears and perform image segmentation according to the distribution of bone marrow cells; a logic management module, which is used to manage the logic structure of the entire system, so that it runs according to a set program, that is, to identify, classify, save and view the digital images of the segmented bone marrow smears; a server communication module, which is used to provide application support for the entire system; through the bone marrow cell management system, the management of bone marrow cells by different hospitals can be realized, the types and categories of bone marrow cells can be more intuitively displayed, and related operations can be performed.

Description

Technical Field

[0001] The present invention belongs to the field of artificial intelligence medical diagnosis, and in particular relates to a classification management system for bone marrow cells. Background Art

[0002] Bone marrow cell morphology is one of the key diagnostic methods in hematopathology and is often used to diagnose a variety of diseases, including leukemia, multiple myeloma, lymphoma, anemia, and pancytopenia. Currently, the diagnosis of bone marrow malignancies is mostly done manually, but with the development of artificial intelligence and automation, bone marrow cell morphology automatic analyzers will be increasingly used in hematopathology. Therefore, it is urgent to develop a simple, efficient bone marrow cell classification management system that is compatible with various bone marrow automated analysis systems and can achieve resource sharing. Summary of the invention

[0003] The purpose of the present invention is to overcome the above-mentioned deficiencies in the prior art and to provide a classification management system for bone marrow cells, which can identify and classify the collected bone marrow cells, and classify and store them according to the bone marrow cell tree model. The system is simple, efficient and shareable, and is compatible with various bone marrow analysis systems, making it convenient for doctors to retrieve, view and analyze the patient's examination results at any time.

[0004] The technical solution adopted by the present invention to solve the above problem is: to provide a classification management system for bone marrow cells, comprising:

[0005] A user interaction interface is used for users to operate the bone marrow cell classification management system, enter the bone marrow cell types and corresponding bone marrow cell images into the system and classify and archive them;

[0006] Digital acquisition control system, used to acquire digital images of bone marrow smears and perform image segmentation based on bone marrow cell distribution;

[0007] The logic management module is used to manage the logic structure of the entire system so that it can run according to the set program, that is, to identify, classify, save and view the digital images of the segmented bone marrow smears;

[0008] Server communication module, used to provide application support for the entire system;

[0009] The acquisition device communication module is used to send the acquired bone marrow smear image information to the digital acquisition control system;

[0010] Data access module, used for users to access the database to view relevant data;

[0011] Sqlite local database, used to store classified bone marrow cell images;

[0012] The local cache module is used to store cache data and files generated during the operation of the entire system.

[0013] Among them, the user interaction interface is connected to the logic management module, the logic management module is respectively connected to the server communication module and the digital acquisition control system, the digital acquisition control system is connected to the acquisition device communication module, the logic management module and the digital acquisition control system both transmit the acquired data to the data access module, and the data access module transmits the received data to the Sqlite local database and the local cache module respectively.

[0014] Preferably, the specific classification method of bone marrow cell classification and archiving is:

[0015] (1) Collect bone marrow cell images, obtain the characteristics of various types of cells contained therein, and identify and classify them;

[0016] (2) Establish a bone marrow cell tree classification model, match the above classification results with the branches of the cell tree one by one, and statistically analyze the results;

[0017] (3) The identified and classified bone marrow cell images are stored in the Sqlite local database according to the corresponding categories and displayed in the form of a cell tree model.

[0018] Preferably, the bone marrow cell tree classification model is divided into 5 levels, the first level is bone marrow cells, which serve as the trunk, the second level is divided into 12 categories, the third level is divided into 45 categories, the fourth level is divided into 97 categories, and the fifth level is divided into 122 categories.

[0019] Preferably, the specific classification categories of the second level are granulocytes, erythrocytes, lymphocytes, monocytes, plasma cells, megakaryocytes, matrix and other cells, bone marrow granules, tumor cells, fragmented cells and division phases, parasites and cells of unknown classification.

[0020] Preferably, when the bone marrow cell image is displayed in a cell tree model, different types of cells in the same level are marked with different colors, and the color of the next level of cells of the same type is the same color as the previous level.

[0021] Preferably, the first level displays the darkest color, and the colors gradually fade from the first level to the fifth level, with the fifth level displaying the lightest color.

[0022] Compared with the prior art, the present invention has the following advantages and effects: bone marrow cells can be classified and managed, the types and quantities of bone marrow cells in different cases can be displayed in the form of statistical lists, and the results can be obtained intuitively; and electronic files facilitate resource sharing and can better diagnose and treat cases; it can be connected to all bone marrow analysis systems, has strong practicality, and has strong application value. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] Figure 1 It is a system structure block diagram of the present invention. DETAILED DESCRIPTION

[0024] The present invention will be further described in detail below with reference to the accompanying drawings and by way of examples. The following examples are intended to explain the present invention but the present invention is not limited to the following examples.

[0025] Example 1.

[0026] See also Figure 1 ,A classification management system for bone marrow cells of the present invention comprises:

[0027] User interaction interface 1, used for users to operate the bone marrow cell classification management system, input the bone marrow cell types and corresponding bone marrow cell images into the system and classify and archive them;

[0028] A digital acquisition control system 3 is used to acquire digital images of bone marrow smears and perform image segmentation based on the distribution of bone marrow cells;

[0029] The logic management module 2 is used to manage the logic structure of the entire system so that it can run according to the set program, that is, to identify, classify, save and view the digital images of the segmented bone marrow smears;

[0030] Server communication module 4, used to provide application support for the entire system;

[0031] The acquisition device communication module 5 is used to send the acquired bone marrow smear image information to the digital acquisition control system;

[0032] Data access module 6, used for users to access the database to view relevant data;

[0033] Sqlite local database 7, used to store images of classified bone marrow cells;

[0034] The local cache module 8 is used to store cache data and files generated during the operation of the entire system.

[0035] Among them, the user interaction interface 1 is connected to the logic management module 2, the logic management module 2 is respectively connected to the server communication module 4 and the digital acquisition control system 3, the digital acquisition control system 3 is connected to the acquisition device communication module 5, the logic management module 2 and the digital acquisition control system 3 both transmit the acquired data to the data access module 6, and the data access module 6 transmits the received data to the Sqlite local database 7 and the local cache module 8 respectively.

[0036] Among them, the method used for specific classification and archiving of bone marrow cells is:

[0037] (1) Collect bone marrow cell images, obtain the characteristics of various types of cells contained therein, and identify and classify them;

[0038] (2) Establish a bone marrow cell tree classification model, match the above classification results with the branches of the cell tree one by one, and statistically analyze the results;

[0039] (3) The identified and classified bone marrow cell images are stored in the Sqlite local database 7 according to the corresponding categories and displayed in the form of a cell tree model.

[0040] The bone marrow cell tree classification model of this embodiment is divided into 5 levels, the first level is bone marrow cells, which serve as the trunk. The second level is divided into 12 categories, namely, granulocytes, erythrocytes, lymphocytes, monocytes, plasma cells, megakaryocytes, matrix and other cells, bone marrow granules, tumor cells, fragmented cells and mitotic phases, parasites, and unclassified cells.

[0041] Specifically, the granulocyte lineage in the second level includes 10 primitive granulocytes, 3 immature granulocytes, 2 mature neutrophils, 2 eosinophils and 2 basophils, the erythroid lineage includes 8 immature erythrocytes and 24 mature erythrocytes, the lymphocyte lineage includes 3 primitive lymphocytes, 2 lymphocytes and 2 heterosexual lymphocytes, the monocyte lineage includes 3 primitive monocytes, 3 immature monocytes and 2 monocytes, the plasma cell lineage includes 2 myeloma cells and 9 mature plasma cells, the megakaryocyte lineage includes 1 primitive megakaryocyte, 3 megakaryocytes and 5 platelets, the matrix and Other cells include 1 mast cell, 1 tissue cell, 4 phagocytes, hemophagocytic cells, macrophages, adipocytes, endothelial cells, fibroblasts, osteoblasts and osteoclasts; tumor cells include 1 non-hematological metastatic cancer cell, Langerhans cells, primitive plasmacytoid dendritic cells; broken cells and mitotic phases include broken cells, degenerate cells, Fallata cells, 4 mitotic phases, plasma bodies and impurities; parasites include Plasmodium, Leishmania, Penicillium marneffei and Histoplasma capsulatum; unclassified cells include primitive blood cells, mixed phenotype primitive cells, immature blood cells and other cells. The above cell categories without numbers indicate that there is no next-level cell category.

[0042] The third level is composed of the subordinate cell categories of the second level, with a total of 45 categories, and the different categories of subordinate cell categories in the third level constitute the fourth level, with a total of 97 categories, and the different categories of subordinate cell categories in the fourth level constitute the fifth level, with a total of 122 categories.

[0043] When the bone marrow cell image of this embodiment is displayed in the cell tree model, different types of cells in the same level are marked with different colors, and the color of the next level of cells of the same type is the same color of the previous level. At the same time, the first level has the darkest color, and the colors gradually fade from the first level to the fifth level, and the fifth level has the lightest color.

[0044] The display categories of bone marrow cells in this embodiment include cell type, number, Chinese name, English name, color, maximum size and minimum size information, etc., which are displayed in the form of a table. The specific classification categories of bone marrow cells used in this system are the most complete at present, which can meet the different needs of hospitals at all levels in China and abroad.

[0045] In addition, it should be noted that the above content described in this specification is only an example of the present invention. Any equivalent changes or simple changes made based on the features and principles described in the patent concept of the present invention are included in the protection scope of the patent of the present invention. Technicians in the technical field of the present invention can make various modifications or supplements to the specific embodiments described or replace them in a similar manner, as long as they do not deviate from the technical solution of the present invention or exceed the scope defined by the claims, they should all fall within the protection scope of the present invention.

Claims

1. A classification management system for bone marrow cells, characterized in that: include: A user interaction interface is used for users to operate the bone marrow cell classification management system, enter the bone marrow cell types and corresponding bone marrow cell images into the system and classify and archive them; Digital acquisition control system, used to acquire digital images of bone marrow smears and perform image segmentation based on bone marrow cell distribution; The logic management module is used to manage the logic structure of the entire system and make it run according to the set program, that is, to identify, classify, save and view the digital images of the segmented bone marrow smears, and to delete and add bone marrow cell images; Server communication module, used to provide application support for the entire system; The acquisition device communication module is used to send the acquired bone marrow smear image information to the digital acquisition control system; Data access module, used for users to access the database to view relevant data; Sqlite local database, used to store classified bone marrow cell images; The local cache module is used to store cache data and files generated during the operation of the entire system; Among them, the user interaction interface is connected to the logic management module, the logic management module is respectively connected to the server communication module and the digital acquisition control system, the digital acquisition control system is connected to the acquisition device communication module, the logic management module and the digital acquisition control system both transmit the acquired data to the data access module, and the data access module transmits the received data to the Sqlite local database and the local cache module respectively.

2. A classification management system for bone marrow cells according to claim 1, characterized in that: The specific classification method of bone marrow cell classification and archiving is: (1) Collect bone marrow cell images, obtain the characteristics of various types of cells contained therein, and identify and classify them; (2) Establish a bone marrow cell tree classification model, match the above classification results with the branches of the cell tree one by one, and statistically analyze the results; (3) The identified and classified bone marrow cell images are stored in the Sqlite local database according to the corresponding categories and displayed in the form of a cell tree model.

3. A classification management system for bone marrow cells according to claim 2, characterized in that: The bone marrow cell tree classification model is divided into five levels. The first level is bone marrow cells, which serve as the trunk. The second level is divided into 12 categories, the third level is divided into 45 categories, the fourth level is divided into 97 categories, and the fifth level is divided into 122 categories.

4. A classification management system for bone marrow cells according to claim 3, characterized in that: The specific classification categories of the second level are granulocytes, erythrocytes, lymphocytes, monocytes, plasma cells, megakaryocytes, matrix and other cells, bone marrow granules, tumor cells, fragmented cells and division phases, parasites and cells of unknown classification.

5. A classification management system for bone marrow cells according to claim 3, characterized in that: When the bone marrow cell image is displayed in a cell tree classification model, different types of cells in the same level are marked with different colors, and the color of the next level of cells of the same type is the same color as the previous level.

6. A classification management system for bone marrow cells according to claim 3, characterized in that: The first level has the darkest display color, and the colors gradually fade from the first level to the fifth level, with the fifth level having the lightest display color.

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