Sample analyzer and sample addition injection device

Abstract

A sample analyzer and a sample addition injection device. The sample addition injection device includes a mounting base; an injection device assembly including a syringe barrel and a plunger rod. The syringe barrel is mounted on the mounting base. The plunger rod has a first end and a second end, and the first end of the plunger rod is axially movably connected within the syringe barrel; a driving assembly including a driving member and a driving belt. The driving member is mounted on the mounting base, and the driving belt is slidably mounted on the mounting base. The second end of the plunger rod is connected to the driving belt; and a transmission assembly. The driving member is connected to the driving belt through the transmission assembly. The driving belt is slidably connected to the mounting base through a guide rail. The transmission assembly is a two-stage gear transmission assembly, and the guide rail is a crossed roller guide rail. The use of a two-stage gear transmission assembly and a crossed roller guide rail in the sample addition injection device can effectively improve its precision.

Description

Technical Field

[0001] The present invention relates to a sample adding device, and particularly to a sample analyzer and a sample adding injection device. Background Art

[0002] In a sample analyzer, a sample adding injection device is usually used to provide negative pressure to a dispensing needle so that the dispensing needle can aspirate a sample or a reagent, or the sample adding injection device provides positive pressure to the dispensing needle so that the dispensing needle can dispense the sample or the reagent. Existing sample adding injection devices generally adopt a lead screw transmission assembly and a linear guide rail, resulting in a relatively low precision of the sample adding injection device. Summary of the Invention

[0003] In one embodiment, a sample analyzer is provided, which is characterized by comprising

[0004] a machine base;

[0005] a dispensing mechanism, including a dispensing needle and a dispensing needle moving device, the dispensing needle moving device is installed on the machine base, the dispensing needle is installed on the dispensing needle moving device, and the dispensing needle moving device is used to drive the dispensing needle to move;

[0006] and a sample adding injection device, the sample adding injection device includes a mounting base, an injection device assembly, a driving assembly and a locking assembly;

[0007] the mounting base is installed on the machine base;

[0008] the injection device assembly includes a syringe barrel and a plunger rod, the syringe barrel is installed on the mounting base, the plunger rod has a first end and a second end, and the first end of the plunger rod is axially movably connected inside the syringe barrel; the syringe barrel is connected to the dispensing needle through a pipeline;

[0009] the driving assembly includes a driving member and a driving belt, the driving member is installed on the mounting base, the driving belt is slidably installed on the mounting base, and the driving member is connected to the driving belt;

[0010] and a transmission assembly, the driving member is connected to the driving belt through the transmission assembly, the driving belt is slidably connected to the mounting base through a guide rail, the transmission assembly is a two-stage gear transmission assembly, the guide rail is a crossed roller guide rail, and the sample adding injection device provides negative pressure to the dispensing needle so that the dispensing needle can aspirate a sample or a reagent, or the sample adding injection device provides positive pressure to the dispensing needle so that the dispensing needle can dispense the sample or the reagent.

[0011] In one embodiment, the transmission assembly includes a reduction gear set and a gear rack set connected to each other; the reduction gear set is connected to the driving member, and the gear rack set is connected to the driving belt.

[0012] In one embodiment, the reduction gear set includes a first reduction gear and a second reduction gear, the gear rack set includes a driving gear and a rack, the first reduction gear is connected to the output shaft of the driving member, a transmission shaft is installed on the mounting base, the second reduction gear and the driving gear are respectively fixedly installed on the transmission shaft, the second reduction gear is meshed and connected with the first reduction gear, the rack is installed on the driving device, and the rack is meshed and connected with the driving gear.

[0013] In one embodiment, the sample adding and injecting device further includes a locking assembly, the locking assembly includes a guiding member and a locking member, the guiding member and the locking member lock the second end of the piston rod on the driving device, the guiding member is located between the second end of the piston rod and the locking member, and both ends of the guiding member are in point contact with the piston rod and the locking member respectively.

[0014] In one embodiment, the guiding member is of a spherical structure.

[0015] In one embodiment, both ends of the guiding member are of a symmetrical hemispherical structure or a conical structure.

[0016] In one embodiment, a clamping groove is provided at one end of the driving device facing the piston rod, the second end of the piston rod is connected in the clamping groove of the driving device, a locking hole is provided at one end of the driving device facing away from the piston rod, and the locking hole extends to communicate with the clamping groove; the guiding member and the locking member are installed in the locking hole.

[0017] In one embodiment, the locking member is a locking screw, and an internal thread adapted to the locking member is provided in the locking hole.

[0018] In one embodiment, the clamping groove is provided with a narrowing portion, a groove is provided at the second end of the piston rod, and the narrowing portion of the clamping groove is clamped in the groove of the piston rod; the clamping groove is provided with an opening extending radially to the side, and the opening is used for clamping the second end of the piston rod.

[0019] In one embodiment, the guide rail is arranged parallel to the piston rod.

[0020] In one embodiment, a spring is provided on the mounting base, one end of the spring is connected to the mounting base, the other end of the spring is connected to the driving device, and the spring is always in a stretched state.

[0021] In one embodiment, one end of the syringe barrel close to the driving device is fixed on the mounting base.

[0022] In one embodiment, an installation portion extending radially along the syringe is provided on the mounting base, and a mounting hole along the axial direction of the syringe is provided on the installation portion. One end of the syringe close to the driver is fixed in the mounting hole of the mounting base.

[0023] In one embodiment, a limiting block and a locking nut are provided on the syringe. The syringe is provided with an external thread connected to the locking nut. The limiting block and the locking nut are located on both axial sides of the installation portion, and the limiting block and the locking nut fix the syringe on the installation portion of the mounting base.

[0024] In one embodiment, a sample addition injection device is provided, including:

[0025] A mounting base;

[0026] An injection device assembly, including a syringe and a plunger rod. The syringe is mounted on the mounting base. The plunger rod has a first end and a second end. The first end of the plunger rod is axially movably connected inside the syringe;

[0027] A driving assembly, including a driving member and a driver. The driving member is mounted on the mounting base. The driver is slidably mounted on the mounting base. The second end of the plunger rod is connected to the driver;

[0028] And a transmission assembly. The driving member is connected to the driver through the transmission assembly. The driver is slidably connected to the mounting base through a guide rail. The transmission assembly is a two-stage gear transmission assembly, and the guide rail is a crossed roller guide rail.

[0029] According to the sample analyzer and the sample addition injection device of the above embodiments, since the sample addition injection device adopts two-stage gear transmission and a crossed roller guide rail, the precision of the sample addition injection device is effectively improved. Description of the Drawings

[0030] Figure 1 It is a schematic structural diagram of a sample addition analyzer in one embodiment;

[0031] Figure 2 It is a schematic structural diagram of a sample addition injection device in one embodiment;

[0032] Figure 3 It is a side view of a partial side section of a sample addition injection device in one embodiment;

[0033] Figure 4 It is a schematic structural diagram of a sample addition injection device in one embodiment;

[0034] Figure 5 It is an axial sectional view of a driver in one embodiment;

[0035] Figure 6Schematic structural diagram of a driver in an embodiment;

[0036] Figure 7 It is Figure 3 The cross-sectional view along B-B in;

[0037] Figure 8 Schematic structural diagram of a transmission component in an embodiment;

[0038] Figure 9 Schematic structural diagram of a sample addition injection device in an embodiment;

[0039] Figure 10 Schematic structural diagram of a sample addition injection device and a sample dispensing mechanism in an embodiment;

[0040] Figure 11 Schematic structural diagram of a sample addition injection device and a reagent dispensing mechanism in an embodiment. Detailed implementation manners

[0041] In a sample analyzer, a sample addition injection device is connected to a sample addition pipeline. The sample addition injection device is used to aspirate a sample through the sample addition pipeline and accurately inject the sample into a reaction cup. After long-term operation, the traditional sample addition injection device will have a problem of decreased accuracy, resulting in inaccurate sample addition and affecting the accuracy of detection.

[0042] The applicant found that the reasons affecting the sample addition accuracy of the sample addition injection device mainly lie in the connection and installation of the injection device components and the structure of the transmission components. Solving any one of these problems can improve the sample addition accuracy of the sample addition injection device. In this application, the connection and installation of the injection device components and the structure of the transmission components are respectively improved to improve the sample addition accuracy of the sample addition injection device.

[0043] The present invention will be further described in detail below in conjunction with the accompanying drawings through specific implementation manners. Similar elements in different implementation manners use related similar element numbers. In the following implementation manners, many detailed descriptions are provided to make this application better understood. However, those skilled in the art can easily recognize that some of these features can be omitted in different situations, or can be replaced by other elements, materials, or methods. In some cases, some operations related to this application are not shown or described in the specification, which is to avoid the core part of this application being overwhelmed by excessive descriptions. For those skilled in the art, it is not necessary to describe these related operations in detail, and they can fully understand the related operations based on the description in the specification and the general technical knowledge in the art.

[0044] In addition, the features, operations, or characteristics described in the specification can be combined in any suitable manner to form various embodiments. Meanwhile, the steps or actions in the method description can also be reordered or adjusted in a manner that would be obvious to those skilled in the art. Therefore, the various sequences in the specification and the drawings are only for clearly describing a certain embodiment and do not mean a necessary sequence, unless it is stated otherwise that a certain sequence must be followed.

[0045] The serial numbers assigned to the components herein, such as "first", "second", etc., are only used to distinguish the objects described and do not have any sequential or technical meaning. And the "connection" and "coupling" mentioned in this application, unless otherwise specified, both include direct and indirect connection (coupling).

[0046] In one embodiment, a sample analyzer is provided. The aspiration and dispensing of samples in this sample analyzer are driven by the sample injection device in the above embodiment.

[0047] Please refer to Figure 1 , a sample analyzer of an embodiment includes a chassis 100 and a sample component 200, a reagent component 400, a dispensing mechanism, a mixing mechanism 600, a reaction component 700, an optical measurement component 800, etc. installed on the chassis 100. Among them, the dispensing mechanism includes a sample dispensing mechanism 300 and a reagent dispensing mechanism 500.

[0048] The sample component 200 is used to carry samples. In some examples, the sample component 200 may include a sample distribution module (SDM, Sample Delivery Module) and a front-end track; in other examples, the sample component 10 may also be a sample tray, and the sample tray includes a plurality of sample positions where samples such as sample tubes can be placed. By rotating its disk structure, the sample tray can schedule the samples to corresponding positions, such as the position for the sample dispensing mechanism 300 to aspirate samples.

[0049] The sample dispensing mechanism 300 is used to aspirate samples and discharge them into the reaction cups to be sampled. For example, the sample dispensing mechanism 300 may include a sample needle 301 and a sample needle moving device 302. The sample needle 301 moves in two or three dimensions in space through the two-dimensional or three-dimensional sample needle moving device 302, so that the sample needle 301 can move to aspirate the samples carried by the sample component 200, and move to the reaction cups to be sampled and discharge the samples into the reaction cups.

[0050] The reagent component 400 is used to carry reagents. In one embodiment, the reagent component 400 can be a reagent tray, which is arranged in a disc shape and has a plurality of positions for carrying reagent containers. The reagent component 400 can rotate and drive the reagent containers carried thereon to rotate, so as to rotate the reagent containers to specific positions, such as the positions where the reagent dispensing mechanism 500 sucks reagents. The number of the reagent components 400 can be one or more.

[0051] The reagent dispensing mechanism 500 is used to suck reagents and discharge them into the reaction cups to which reagents are to be added. In one embodiment, the reagent dispensing mechanism 500 can include a reagent needle 501 and a reagent needle moving device 502. The reagent needle 501 performs two-dimensional or three-dimensional movement in space through the two-dimensional or three-dimensional reagent needle moving device 502, so that the reagent needle 501 can move to suck the reagents carried by the reagent component 400, and move to the reaction cups to which reagents are to be added, and discharge the reagents into the reaction cups.

[0052] The mixing mechanism 600 is used to mix the reaction liquid that needs to be mixed in the reaction cups. The number of the mixing mechanisms 600 can be one or more.

[0053] The reaction component 700 has at least one placement position, and the placement position is used to place the reaction cups and incubate the reaction liquid in the reaction cups. For example, the reaction component 700 can be a reaction tray, which is arranged in a disc shape and has one or more placement positions for placing reaction cups. The reaction tray can rotate and drive the reaction cups in its placement positions to rotate, so as to schedule the reaction cups in the reaction tray and incubate the reaction liquid in the reaction cups.

[0054] The optical measurement component 800 is used to perform optical measurement on the reaction liquid after incubation to obtain the reaction data of the sample. For example, the optical measurement component 800 detects the luminescence intensity of the reaction liquid to be measured, and calculates the concentration of the component to be measured in the sample through a calibration curve. In one embodiment, the optical measurement component 800 is separately arranged outside the reaction component 700.

[0055] The sample needle 301 and the reagent needle 501 are dispensing needles with different functions. The sample needle 301 is used for sampling and discharging samples, and the reagent needle 501 is used for sucking and discharging reagents. The sample needle moving device 302 and the reagent needle moving device 502 are dispensing needle moving devices for different dispensing needles. The sample needle moving device 302 is used to drive the movement of the sample needle 301, and the reagent needle moving device 502 is used to drive the movement of the reagent needle 501.

[0056] In this embodiment, a sample addition injection device 900 is further provided on the machine base 100. The sample addition injection device 900 serves as a driving member and is connected to the sample needle 301. The sample addition injection device 900 is used to provide negative pressure or positive pressure for the sample needle 301 to drive the sample needle 301 to aspirate and eject samples. In some embodiments, the sample addition injection device 900 is connected to the reagent needle 501, and the sample addition injection device 900 is used to provide negative pressure or positive pressure for the reagent needle 501 to drive the reagent needle 501 to aspirate and eject reagents.

[0057] Please refer to Figure 2 and Figure 3 , in this embodiment, the sample addition injection device mainly includes a mounting base 10, an injection device assembly 20, a driving assembly 30, a locking assembly 40, and a transmission assembly 50. Among them, the mounting base 10 is a supporting component of the entire sample addition injection device, and the mounting base 10 is formed by splicing a plurality of metal plates. The injection device assembly 20 is also called a syringe body, and the injection device assembly 20 is any one of a piston syringe and a plunger syringe. The injection device assembly 20 includes a syringe barrel 21 and a plunger rod 22. The syringe barrel 21 is installed on the mounting base 10, and the plunger rod 22 is installed inside the syringe barrel 21. The driving assembly 30 includes a driving member 31 and a driving belt 32. The driving member 31 is fixedly installed on the mounting base 10, and the driving belt 32 is movably installed on the mounting base 10. One end of the plunger rod 22 exposed from the syringe barrel 21 is connected to the driving belt 32 through the locking assembly 40. The transmission assembly 50 is installed on the mounting base 10, and the driving member 31 is connected to the driving belt 32 through the transmission assembly 50.

[0058] The working principle of the sample addition injection device is as follows: The driving member 31 drives the driving belt 32 to move linearly back and forth through the transmission assembly 50, and the driving belt 32 drives the plunger rod 22 to move linearly back and forth, thereby driving the sample addition injection device to form negative pressure or positive pressure.

[0059] In this embodiment, the mounting base 10 includes a mounting plate 11 and a mounting bracket 12. The injection device assembly 20 and the driving assembly 30 are respectively installed on both sides of the mounting plate 11. The syringe barrel 21 of the injection device assembly 20 is directly installed on one side surface of the mounting plate 11. The mounting bracket 12 is installed on the side surface of the mounting plate 11 facing away from the injection device assembly 20, and the driving member 31 is installed on the mounting bracket 12. An avoidance hole 13 parallel to the plunger rod 22 is provided on the mounting plate 11, and the avoidance hole 13 is a strip-shaped structure. The driving belt 32 is a slider, and the driving belt 32 is slidably installed on the mounting plate 11 through a guide rail 33. The guide rail 33 is arranged parallel to the plunger rod 22, and the driving belt 32, the guide rail 33, and the plunger rod 22 are located on the same side of the mounting plate 11.

[0060] The housing 14 is also installed on the mounting base 10. The housing 14 is installed on the mounting plate 11, and the housing 14 covers the mounting bracket 12, the driving assembly 30 and the transmission assembly 50 to prevent the driving assembly 30 and the transmission assembly 50 from being interfered by the outside.

[0061] In this embodiment, the two ends of the plunger rod 22 are respectively defined as the first end and the second end. The first end of the plunger rod 22 is connected inside the syringe barrel 21. The first end of the plunger rod 22 can axially move inside the syringe barrel 21. The second end of the plunger rod 22 exposes out of the syringe barrel 21, and the second end of the plunger rod 22 exposes out of the syringe barrel 21 and is connected to the driver 32 through the locking assembly 40.

[0062] Please refer to Figure 4 、 Figure 5 and Figure 6 . The locking assembly 40 includes a guiding member 41 and a locking member 42. The guiding member 41 is preferably a guiding steel ball. The guiding member 41 can also be a structure with hemispherical or conical ends at both ends, and a cylindrical or tubular structure in the middle between the two hemispherical or conical ends at both ends. Both ends of the guiding member 41 are contact points; the locking member 42 is a locking screw.

[0063] The driver 32 is provided with a slot 321 and a locking hole 322. The slot 321 faces the plunger rod 22, and the notch of the slot 321 is narrowed to form a narrowing part. The second end of the plunger rod 22 is provided with an annular groove 221 adapted to the slot 321. The second end of the plunger rod 22 is inserted into the slot 321, and the narrowing part of the slot 321 is clamped in the annular groove 221 of the plunger rod 22. Furthermore, the narrowing part can limit the axial freedom degree of the plunger rod 22.

[0064] The guide rail 33 preferably adopts a crossed roller guide rail. The crossed roller guide rail has the advantages of small resistance, high precision and strong stability, and can ensure the accuracy of the linear movement of the driver 32.

[0065] In order to enable the plunger rod 22 to be installed and disassembled with the slot 321 of the driver 32, an opening is provided on one axial side of the slot 321, and the second end of the plunger rod 22 can be radially inserted into or removed from the side opening of the slot 321. The axial width of the annular groove 221 of the plunger rod 22 is greater than the axial thickness of the narrowing part of the slot 321. Furthermore, the plunger rod 22 can be relatively easily inserted into and removed from the slot 321.

[0066] In other embodiments, a flange structure is provided at the second end of the plunger rod 22, that is, the second end of the plunger rod 22 is a T-shaped structure, and the limit installation of the plunger rod 22 can also be realized.

[0067] In this embodiment, the locking assembly 40 and the narrowing portion of the card slot 321 cooperate to limit the axial degree of freedom of the second end of the plug rod 22. The locking hole 322 of the driver 32 and the card slot 321 are arranged on the axis of the plug rod 22. The locking hole 322 is located on the other side relative to the card slot 321, and the locking hole 322 communicates with the card slot 321. An accommodation cavity is provided at one end of the locking hole 322 close to the card slot 321. The accommodation cavity is larger than the volume of the guiding member 41 (guiding steel ball). The guiding member 41 can be installed in the accommodation cavity of the locking hole 322. The end of the locking hole 322 far from the card slot 321 is provided as a threaded hole, and the locking member 42 (locking screw) is installed in the threaded hole of the locking hole 322. The end of the locking member 42 located in the threaded hole abuts against one end of the guiding member 41, and the other end of the guiding member 41 abuts against the end face of the second end of the plug rod 22. The axial locking force provided by the guiding member 41 is applied to the second end of the plug rod 22 in a point contact manner, thereby locking the plug rod 22 on the driver 32.

[0068] The accommodation cavity of the locking hole 322 has an inner diameter adapted to the guiding member 41 for limiting the radial position of the guiding member 41, so that the guiding member 41 and the locking member 42 are aligned in a straight line. In particular, the guiding member 41 and the locking member 42 are aligned on the axis of the plug rod 22 to avoid generating radial component forces, thereby being able to avoid the inclination of the plug rod 22 and improve the stability of the plug rod 22. In some embodiments, the guiding member 41 and the locking member 42 are aligned in a straight line, and this straight line is parallel to the axis of the plug rod 22, which can also avoid generating radial component forces and can also improve the stability of the plug rod 22.

[0069] In some embodiments, the accommodation cavity of the locking hole 322 can also be classified as a part of the card slot 321, or as a part independent of the locking hole 322 and the card slot 321. The accommodation cavity communicates with the locking hole 322 and the card slot 321 respectively.

[0070] In this embodiment, since the plug rod 22 of the injection device assembly 20 is connected to the driver 32 through the locking assembly 40, the locking assembly 40 includes a guiding member 41 and a locking member 42. The guiding member 41 is a guiding steel ball, and the locking member 42 is a locking screw. The guiding steel ball is located between the plug rod 22 and the locking screw, and the two ends of the guiding steel ball are in point contact with the plug rod 22 and the locking screw respectively. The point contact setting enables the locking screw to apply an axial locking force to the plug rod 22 without radial component forces, so that the plug rod 22 does not tilt during the installation process. After multiple uses, the position accuracy can still be maintained, ensuring the sampling accuracy for multiple uses.

[0071] Please refer to Figure 7 and Figure 8, in this embodiment, the transmission assembly 50 is a two-stage transmission structure. The transmission assembly 50 is installed on the mounting plate 11 and is located inside the housing 14. The transmission assembly 50 includes a reduction gear set 51 and a gear-rack set 52. The reduction gear set 51 is the first-stage transmission component, and the gear-rack set 52 is the second-stage transmission component. The reduction gear set 51 is used for reducing speed and increasing torque, and the gear-rack set 52 is used for converting rotational drive into linear drive.

[0072] The driving member 31 is a motor. The reduction gear set 51 includes a first reduction gear 511 and a second reduction gear 512. The first reduction gear 511 is a small gear, and the second reduction gear 512 is a large gear. The first reduction gear 511 and the second reduction gear 512 are meshed and connected. There is a preset transmission ratio between the first reduction gear 511 and the second reduction gear 512, such as a transmission ratio of 0.1. The first reduction gear 511 is installed on the output shaft of the driving member 31, and the second reduction gear 512 is fixedly installed on the transmission shaft 53. The transmission shaft 53 is rotatably installed on the mounting bracket 12 through bearings.

[0073] The gear-rack set 52 includes a gear 521 and a rack 522. The gear 521 is fixedly installed on the transmission shaft 53, and the gear 521 rotates synchronously with the second reduction gear 512. The rack 522 is connected to the actuator 32 and is also meshed with the gear 521.

[0074] The transmission principle of the transmission assembly 50 is as follows: The driving member 31 drives the first reduction gear 511 to rotate. The first reduction gear 511 drives the second reduction gear 512 to rotate. The second reduction gear 512 outputs a relatively lower speed than the first reduction gear 511. The second reduction gear 512 rotates synchronously with the gear 521 through the transmission shaft 53. The gear 521 drives the rack 522 to move linearly. Further, the rack 522 drives the actuator 32 to move linearly.

[0075] In this embodiment, the transmission assembly 50 adopts two-stage gear transmission. A transmission chain is formed through the combination of the reduction gear set 51 and the gear-rack set 52. The reduction gear set 51 can play the role of reducing speed and increasing torque, enabling the driving member 31 to reciprocate the piston rod 22 with a smaller driving force, ensuring the driving accuracy of the driving member 31, thus ensuring the accuracy during the long-term movement of the piston rod 22, and further ensuring the sampling accuracy.

[0076] Please refer to Figure 4, in this embodiment, a spring 15 is further installed on the mounting base 10. An installation post 16 is provided on the surface of the mounting plate 11 facing away from the injection device assembly 20. An installation post 34 is also provided at one end of the driver 32 passing through the avoidance hole 13. The installation post 16 and the installation post 34 are aligned and installed on the center line in the length direction of the avoidance hole 13, or the line connecting the installation post 16 and the installation post 34 is parallel to the movement direction of the driver 32. Two ends of the spring 15 are respectively connected to the installation post 16 and the installation post 34. The spring 15 is always in a stretched state. The spring 15 is used to provide a pre-tightening force for the driver 32. The spring 15 can eliminate the clearance generated during the transmission between the first reduction gear 511 and the second reduction gear 512, and can eliminate the clearance generated during the transmission between the gear 521 and the rack 522, thereby ensuring the transmission accuracy between the first reduction gear 511 and the second reduction gear 512 and between the gear 521 and the rack 522.

[0077] In one embodiment, the transmission assembly 50 of the sample addition and injection device includes a lead screw and a nut. The lead screw is installed on the mounting base 10 through a bearing. One end of the lead screw is connected to the driving member 31. The nut is connected to the lead screw, and the nut is connected to the driver 32. The driving member 31 can drive the linear reciprocating movement of the driver 32 through the lead screw and the nut. In this sample addition and injection device, due to the provision of the locking assembly 40, the locking assembly 40 can axially lock the plunger rod, improving the stability of the plunger rod. Therefore, this sample addition and injection device still has higher sample addition accuracy and stability compared with traditional devices.

[0078] In one embodiment, the driving member 31 of the sample addition and injection device is a cylinder or a linear motor, and the above-mentioned transmission assembly 50 is not provided. The output end of the driving member 31 is directly connected to the driver 32, and the driving member 31 directly drives the linear reciprocating movement of the driver 32. In this sample addition and injection device, due to the provision of the locking assembly 40, the locking assembly 40 can axially lock the plunger rod, improving the stability of the plunger rod. Therefore, this sample addition and injection device still has higher sample addition accuracy and stability compared with traditional devices.

[0079] In one embodiment, the above-mentioned locking assembly 40 is changed to a traditional locking device. Due to the provision of the transmission assembly 50 in the sample addition and injection device, the transmission assembly 50 has the function of reducing speed and increasing distance, reducing the driving torque of the driving member 31, and improving the stability of the output of the driving member 31, so that this sample addition and injection device still has higher sample addition accuracy and stability compared with traditional devices.

[0080] Please refer to Figure 9 , in this embodiment, a protruding installation portion 111 is provided on the mounting plate 11. The installation portion 111 is a plate-like structure, and the installation portion 111 is provided with an installation hole.

[0081] Both ends of the syringe 21 are defined as the first end and the second end. The first end of the syringe 21 is connected to the sample needle 301 through a pipeline. The second end of the syringe 21 is inserted into the mounting hole of the mounting part 111. A limit block 211 and a locking nut 212 are mounted on the second end of the syringe 21. The limit block 211 is fixed on the syringe 21 by means of threaded connection or clamping. The limit block 211 and the syringe 21 can also be an integral structure. An external thread is provided at the end of the second end of the limit block 211. The locking nut 212 is mounted on the syringe 21 by means of threaded connection. The limit block 211 and the locking nut 212 are respectively located on both sides of the mounting part 111. Under the action of the locking force of the locking nut 212, the limit block 211 and the locking nut 212 lock the syringe 21 on the mounting part 111 of the mounting plate 11.

[0082] In this embodiment, since the plunger rod 22 is connected to the second end of the syringe 21, during the movement of the plunger rod 22, the second end of the syringe 21 is more likely to shake relative to the first end. Therefore, by axially locking the second end of the syringe 21 on the mounting part 111 with the locking nut 212, the stability of the syringe 21 can be ensured, thereby ensuring the accuracy of the movement of the plunger rod 22 and the sample addition accuracy.

[0083] Please refer to Figure 10 , in this embodiment, the sample addition injection device 900 is connected to the sample dispensing mechanism 300. Among them, the mounting base 10 is mounted on the machine base 100. The sample needle 301 is connected to the syringe 21 through a pipeline. The sample addition injection device 900 provides positive pressure and negative pressure drive for the sample needle 301 to realize the sample ejection and suction of the sample needle 301.

[0084] Improvements are made to at least one of the installation of the syringe 21, the installation of the plunger rod 22 and the transmission assembly 50 in the sample addition injection device 900. Compared with the traditional sample addition injection device, the sample addition injection device 900 can ensure the sample addition accuracy of the sample dispensing mechanism 300.

[0085] Please refer to Figure 11 , in one embodiment, the sample addition injection device 900 is connected to the reagent dispensing mechanism 500. Among them, the mounting base 10 is mounted on the machine base 100. The reagent needle 501 is connected to the syringe 21 through a pipeline. The sample addition injection device 900 provides positive pressure and negative pressure drive for the reagent needle 501 to realize the reagent ejection and suction of the reagent needle 501.

[0086] Improvements are made to at least one of the installation of the syringe 21, the installation of the plunger rod 22 and the transmission assembly 50 in the sample addition injection device 900. Compared with the traditional sample addition injection device, the sample addition injection device 900 can ensure the reagent addition accuracy of the reagent dispensing mechanism 500.

[0087] The above uses specific examples to elaborate on the present invention, which is only used to help understand the present invention and is not intended to limit the present invention. For those skilled in the art to which the present invention pertains, based on the idea of the present invention, several simple deductions, deformations or substitutions can also be made.

Claims

1. A sample analyzer, characterized in that, including a base; a dispensing mechanism including a dispensing needle and a dispensing needle moving device, the dispensing needle moving device being mounted on the base, the dispensing needle being mounted on the dispensing needle moving device, and the dispensing needle moving device being configured to drive the dispensing needle to move; and a sample adding and injection device, the sample adding and injection device including a mounting seat, an injection device assembly, and a driving assembly; the mounting seat being mounted on the base; the injection device assembly including a syringe barrel and a plunger rod, the syringe barrel being mounted on the mounting seat, the plunger rod having a first end and a second end, the first end of the plunger rod being axially movably connected within the syringe barrel; the syringe barrel being connected to the dispensing needle through a pipeline; the driving assembly including a driving member and a driver, the driving member being mounted on the mounting seat, the driver being slidably mounted on the mounting seat, and the second end of the plunger rod being connected to the driver; and a transmission assembly, the driving member being connected to the driver through the transmission assembly, the driver being slidably connected to the mounting seat through a guide rail, the transmission assembly being a two-stage gear transmission assembly, the guide rail being a crossed roller guide rail, the sample adding and injection device providing negative pressure to the dispensing needle to enable the dispensing needle to aspirate a sample or a reagent, or the sample adding and injection device providing positive pressure to the dispensing needle to enable the dispensing needle to dispense the sample or the reagent; a spring is provided on the mounting seat, one end of the spring being connected to the mounting seat, the other end of the spring being connected to the driver, the spring always being in a stretched state, and the spring being configured to provide a pre-tightening force to the driver.

2. The sample analyzer according to claim 1, characterized in that, The two-stage gear transmission assembly includes a reduction gear set and a gear and rack set connected to each other; the reduction gear set is connected to the driving member, and the gear and rack set is connected to the driver.

3. The sample analyzer according to claim 2, characterized in that, The reduction gear set includes a first reduction gear and a second reduction gear, the gear and rack set includes a transmission gear and a rack, the first reduction gear is connected to the output shaft of the driving member, a transmission shaft is mounted on the mounting seat, the second reduction gear and the transmission gear are respectively fixedly mounted on the transmission shaft, the second reduction gear is meshed and connected to the first reduction gear, the rack is mounted on the driver, and the rack is meshed and connected to the transmission gear.

4. The sample analyzer according to claim 1, wherein, The sample adding and injection device further includes a locking assembly, the locking assembly including a guiding member and a locking member, the guiding member and the locking member locking the second end of the plunger rod on the driver, the guiding member being located between the second end of the plunger rod and the locking member, and both ends of the guiding member being in point contact with the plunger rod and the locking member respectively.

5. The sample analyzer according to claim 4, characterized in that, The guiding member is a spherical structure.

6. The sample analyzer according to claim 4, characterized in that, Both ends of the guiding member are symmetric hemispherical structures or conical structures.

7. The sample analyzer according to claim 4, wherein, A clamping groove is provided at one end of the driver facing the plunger rod, the second end of the plunger rod is connected in the clamping groove of the driver, a locking hole is provided at one end of the driver facing away from the plunger rod, and the locking hole extends to communicate with the clamping groove; the guiding member and the locking member are mounted in the locking hole.

8. The sample analyzer according to claim 7, wherein, The locking member is a locking screw, and internal threads adapted to the locking member are provided in the locking hole.

9. The sample analyzer according to claim 7, characterized in that, The card slot is provided with a narrowing portion, and the second end of the plug rod is provided with a groove, and the narrowing portion of the card slot is clamped in the groove of the plug rod; the card slot is provided with an opening extending radially to the side, and the opening is used to snap into the second end of the plug rod.

10. The sample analyzer according to claim 1, wherein, The guide rail is arranged parallel to the plug rod.

11. The sample analyzer according to any one of claims 1 to 10, characterized in that, One end of the syringe near the driver is fixed on the mounting base.

12. The sample analyzer according to claim 11, wherein The mounting base is provided with a mounting portion extending radially along the syringe, and the mounting portion is provided with a mounting hole along the axial direction of the syringe. One end of the syringe near the driver is fixed in the mounting hole of the mounting base.

13. The sample analyzer according to claim 12, characterized in that, The syringe is provided with a limit block and a locking nut. The syringe is provided with an external thread connected to the locking nut. The limit block and the locking nut are located on both axial sides of the mounting portion. The limit block and the locking nut fix the syringe on the mounting portion of the mounting base.

14. A sample addition injection device, characterized in that, Comprising: A mounting base; An injection device assembly, including a syringe and a plug rod. The syringe is mounted on the mounting base. The plug rod has a first end and a second end. The first end of the plug rod is axially movably connected in the syringe; A drive assembly, including a drive member and a driver. The drive member is mounted on the mounting base. The driver is slidably mounted on the mounting base. The second end of the plug rod is connected to the driver; And a transmission assembly. The drive member is connected to the driver through the transmission assembly. The driver is slidably connected to the mounting base through a guide rail. The transmission assembly is a two-stage gear transmission assembly. The guide rail is a crossed roller guide rail; A spring is provided on the mounting base. One end of the spring is connected to the mounting base, and the other end of the spring is connected to the driver. The spring is always in a stretched state. The spring is used to provide a pre-tightening force for the driver.

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