Slide basket and sample analyzer

Abstract

The present invention relates to a slide basket and a sample analyzer. The slide basket includes: a card bin, inside which there are positions for accommodating slide racks; and a limiting member, which is installed inside the card bin, and the limiting member includes a connecting portion and a limiting portion connected to the connecting portion; by applying a first force to the second limiting member to make the second limiting member in an unlocked state, the slide rack can be placed into or taken out of the card bin, so that the slide rack can be introduced into or exported from the position; and by applying a second force to the second limiting member to make the second limiting member in a locked state, the limiting portion can be engaged with the limiting holes on the slide rack to lock the slide rack on the position, thereby preventing the slide rack from sliding out of the slide basket during the transportation of the slide basket.

Description

Technical Field

[0001] The present invention relates to the technical field of biological specimen detection equipment, and particularly to a slide basket and a sample analyzer. Background Art

[0002] When analyzing a biological specimen, the biological specimen needs to be placed on a slide, and the slide is placed on a slide rack. Then, the slide rack is placed under a microscope for observation, detection, and comparison.

[0003] To improve the transfer efficiency, multiple slide racks are usually placed in a slide basket to transfer a larger number of slide racks at one time. Currently, after the slide rack is placed in the slide basket, it has a clearance fit with the slide basket. During the transfer process, once the slide basket tilts, the slide will slide out of the slide basket, causing sample damage. Summary of the Invention

[0004] Based on this, it is necessary to provide a slide basket for the problem that the slide rack is likely to slide out of the slide basket. At the same time, a sample analyzer is also provided.

[0005] A slide basket, characterized in that the slide basket includes:

[0006] A card slot, inside which there is a position for accommodating a slide rack; and

[0007] A limiting member, which is installed inside the card slot, and the limiting member includes a connecting portion and a limiting portion connected to the connecting portion;

[0008] Wherein, the limiting member can move relative to the card slot and has an unlocked state and a locked state; in the unlocked state, the limiting portion is misaligned with the position; in the locked state, the limiting portion is aligned with the position.

[0009] A sample analyzer, comprising:

[0010] The above-mentioned slide basket;

[0011] A slide rack, on which a limiting hole is provided; and

[0012] A microscope mechanism, which is used to detect the sample on the slide rack.

[0013] Wherein, when the limiting member is in the unlocked state, the slide rack can be inserted into or taken out of the position; when the limiting member is in the locked state, the limiting portion is engaged with the limiting hole to lock the slide rack in the position. Description of the Drawings

[0014] Figure 1Schematic structural diagram of a sample analyzer according to an embodiment of the present invention;

[0015] Figure 2 is Figure 1 Schematic structural diagrams of three perspectives of a slide holder in the sample analyzer shown;

[0016] Figure 3 is Figure 2 Exploded schematic structural diagrams of two perspectives of the slide holder shown in ;

[0017] Figure 4 is Figure 1 Rear view, front view of the cartridge mechanism in the sample analyzer shown and schematic diagram of the state where the limiting member is engaged with the slide holder;

[0018] Figure 5 is Figure 4 Exploded schematic structural diagram of the cartridge mechanism shown;

[0019] Figure 6 is Figure 1 Schematic structural diagram of the first driving component in the conveying mechanism shown;

[0020] Figure 7 is Figure 1 Assembly schematic diagram when the second driving component and the dragging component in the conveying mechanism shown are assembled together and exploded schematic diagram when they are separated;

[0021] Figure 8 is Figure 1 Schematic structural diagrams of three perspectives of the oil dropping mechanism in the sample analyzer shown. Detailed implementation manners

[0022] In order to make the above objects, features and advantages of the present invention more obvious and understandable, the following will describe the detailed implementation manners of the present invention in conjunction with the accompanying drawings. Many specific details are set forth in the following description in order to fully understand the present invention. However, the present invention can be implemented in many other ways different from those described herein, and those skilled in the art can make similar improvements without departing from the connotation of the present invention. Therefore, the present invention is not limited by the specific embodiments disclosed below.

[0023] In the description of the present invention, it should be understood that the orientation or positional relationship indicated by terms such as "center", "longitudinal", "transverse", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "radial", "circumferential", etc. is based on the orientation or positional relationship shown in the drawings. It is only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be construed as a limitation on the present invention.

[0024] In addition, the terms "first" and "second" are only used for descriptive purposes and should not be construed as indicating or implying relative importance or implicitly specifying the quantity of the indicated technical features. Thus, the features defined with "first" and "second" may explicitly or implicitly include at least one of such features. In the description of the present invention, the meaning of "a plurality" is at least two, such as two, three, etc., unless otherwise specifically and clearly defined.

[0025] In the present invention, unless otherwise clearly specified and defined, terms such as "mounted", "connected", "coupled", "fixed", etc. shall be understood in a broad sense. For example, it may be a fixed connection, a detachable connection, or integrated; it may be a mechanical connection or an electrical connection; it may be directly connected or indirectly connected through an intermediate medium, and it may be the internal communication of two elements or the interaction relationship between two elements, unless otherwise clearly defined. For those of ordinary skill in the art, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0026] In the present invention, unless otherwise clearly specified and defined, the first feature being "on" or "under" the second feature may be that the first and second features are in direct contact, or the first and second features are indirectly in contact through an intermediate medium. Moreover, the first feature being "above", "over" and "on top of" the second feature may be that the first feature is directly above or obliquely above the second feature, or merely indicates that the first feature has a higher horizontal height than the second feature. The first feature being "under", "beneath" and "underneath" the second feature may be that the first feature is directly below or obliquely below the second feature, or merely indicates that the first feature has a lower horizontal height than the second feature.

[0027] It should be noted that when an element is referred to as "fixed to" or "disposed on" another element, it can be directly on the other element or there may also be an intermediate element. When an element is considered to be "connected" to another element, it can be directly connected to the other element or there may be an intermediate element at the same time. The terms "vertical", "horizontal", "upper", "lower", "left", "right" and similar expressions used herein are only for illustrative purposes and do not represent the only implementation.

[0028] Combined with Figures 1 to 8 As shown, a sample scanner 10 according to an embodiment of the present invention includes a microscope mechanism 11, a cartridge mechanism 21, a transfer mechanism 31, and an oil dripping mechanism 41. Among them, the microscope mechanism 11 includes a scanning platform 120 and a microscope assembly 110 suspended above the scanning platform 120. The specimen placed on the scanning platform 120 can be detected through the microscope assembly 110. The cartridge mechanism 21 is used to carry a large number of slides carrying biological specimens. The transfer mechanism 31 can transfer the slides of the cartridge mechanism 21 to the scanning platform 120. The oil dripping mechanism 41 is used to drip immersion oil onto the slide within the field of view of the microscope assembly 110 to enable the microscope assembly 110 to present better imaging quality.

[0029] Combined with Figures 2 to 4 As shown, in some embodiments, the cartridge mechanism 21 includes a slide holder 22 and a slide basket 26. The slide holder 22 is used to carry slides, and the slide holder 22 is installed in the slide basket 26. Specifically, by placing the slide on the slide holder 22, it is possible to prevent the operator from directly contacting the slide and causing contamination of the specimen. Moreover, multiple slides can be placed on the slide holder 22, enabling the microscope assembly 110 to detect multiple specimens. Multiple slide holders 22 can be installed in the slide basket 26 to achieve the loading and transportation of multiple slide holders 22.

[0030] Specifically, in this embodiment, the slide holder 22 includes a main body 23 and a clamping assembly 24. The main body 23 includes a surrounding edge 231 and a supporting portion 232 connected to the surrounding edge 231. The supporting portion 232 is used to support the slide, and the clamping assembly 24 is disposed on the surrounding edge 231. The clamping assembly 24 includes a first clamping structure 24a and a second clamping structure 24b. Among them, a picking and placing operation position 233 is formed on the surrounding edge 231. The picking and placing operation position 233 and the first clamping structure 24a are oppositely arranged on both sides of the supporting portion 232. The second clamping structure 24b and the picking and placing operation position 233 are located on the same side of the supporting portion 232, and the second clamping structures 24b are provided on both sides of the picking and placing operation position 233. The slide can be picked and placed on the supporting portion 232 through the picking and placing operation position 233. The first clamping structure 24a and the second clamping structure 24b cooperate to clamp the slide along the longitudinal direction of the slide. By arranging the picking and placing operation position 233 between the two second clamping structures 24b and making the picking and placing operation position 233 opposite to the first clamping structure 24a, the two second clamping structures 24b and the first clamping structure 24a are distributed in a triangular shape, so as to realize stable clamping of the slide. At the same time, through the picking and placing operation position 233 between the two second clamping structures 24b, a larger operation space can be provided for the operator to pick and place the slide on the supporting portion 232, improving the convenience of the slide picking and placing operation.

[0031] Further, the picking and placing operation position 233 extends in the direction towards the first clamping structure 24a and extends beyond the second clamping structure 24b. In this way, after the slide is placed on the supporting portion 232, a local area on the slide corresponds to the picking and placing operation position 233, so that the operator can have a larger contact area with the slide to ensure stable contact when picking and placing the slide and provide a relatively stable clamping force to prevent the slide from falling. Specifically, the picking and placing operation position 233 is a groove-like structure extending from the surrounding edge 231 towards the supporting portion 232, so that the end of a human finger can be received therein.

[0032] Specifically, the slide has a specimen area and a barcode area. Among them, the specimen area carries a biological specimen, and the barcode area has a barcode for numbering and identifying the corresponding specimen. A hollow area 234 corresponding to the specimen area is formed on the supporting portion 232, and light can irradiate the specimen area through the hollow area 234. The supporting portion 232 between the hollow area 234 and the picking and placing operation position 233 corresponds to the barcode area. Therefore, the operator can hold the periphery of the barcode area to pick and place the slide, thereby avoiding contacting the specimen area and causing contamination to the biological specimen. Further, the supporting portion 232 is in a flat plate shape, and both sides of the specimen area can be attached to the supporting portion 232 along the longitudinal direction of the slide. In this way, the supporting portion 232 can stably support the slide.

[0033] Specifically, the first clamping structure 24a includes a pressing block 241 and a first elastic member 242. The pressing block 241 is slidably connected to the surrounding edge 231 so as to be able to approach or move away from the picking and placing operation position 233. The first elastic member 242 elastically acts on the pressing block 241 to provide a clamping force for clamping the glass slide for the pressing block 241. By moving the pressing block 241 away from the picking and placing operation position 233, the distance between the pressing block 241 and the second clamping structure 24b is increased to facilitate placing the glass slide between the two or removing the glass slide from between the two. When the external force is withdrawn, the first elastic member 242 can apply an elastic acting force to the pressing block 241 to force the pressing block 241 to approach the picking and placing operation position 233, so that the pressing block 241 and the second clamping structure 24b can jointly clamp the glass slide.

[0034] In some embodiments, sliding blocks 243 are provided on both opposite sides of the pressing block 241. A sliding groove 239 extending in the direction towards the picking and placing operation position 233 is formed on the surrounding edge 231. The two sliding blocks 243 are both engaged with the sliding groove 239 to be able to slide along the sliding groove 239, thereby realizing the sliding of the pressing block 241. In some embodiments, a first limiting member 244 is connected to the pressing block 241. A limiting groove 235 extending in the direction towards the picking and placing operation position 233 is formed on the surrounding edge 231. The first limiting member 244 passes through the limiting groove 235. The limiting groove 235 cooperates with the first limiting member 244 to limit the maximum sliding stroke of the pressing block 241. The limiting groove 235 is a strip-shaped groove. When the pressing block 241 slides relative to the surrounding edge 231, the first limiting member 244 moves in the limiting groove 235. The two ends of the limiting groove 235 can abut against the first limiting member 244 to constitute the two limit positions of the sliding of the pressing block 241. Specifically, the first limiting member 244 is a pin threadedly connected to the pressing block 241. In some embodiments, a guiding member 236 is connected to the surrounding edge 231. A guiding groove 245 extending in the direction towards the picking and placing operation position 233 is formed on the pressing block 241. The guiding member 236 cooperates with the guiding groove 245 to guide the pressing block 241. In addition, the guiding groove 245 is a blind groove, and the guiding member 236 is a guiding pin threadedly connected to the surrounding edge 231. The guiding member 236 can abut against the bottom wall of the guiding groove 245 to constitute a stroke limit for the movement of the pressing block 241, so as to be able to shorten the stroke of the pressing block 241 and enable the pressing block 241 to move within a smaller stroke range to achieve the clamping and relaxation of the glass slide. It should be noted that in other embodiments, the arrangement positions of the sliding groove 239 and the sliding block 243, the arrangement positions of the first limiting member 244 and the limiting groove 235, and the arrangement positions of the guiding member 236 and the guiding groove 245 can all be interchanged.

[0035] In some embodiments, a first receiving cavity 246 is formed in the pressing block 241, and a second receiving cavity 237 is formed through the surrounding edge 231. The first clamping structure 24a includes an adjusting member 247 threadedly connected to the second receiving cavity 237. One end of the first elastic member 242 is received in the first receiving cavity 246 and abuts against the pressing block 241, and the other end of the first elastic member 242 is received in the second receiving cavity 237 and abuts against the adjusting member 247. The first elastic member 242 abuts against the pressing block 241 to provide an elastic acting force for the pressing block 241 to clamp the glass slide. By rotating the adjusting member 247, the position of the adjusting member 247 relative to the second receiving cavity 237 is changed, so as to change the pressing degree of the adjusting member 247 on the first elastic member 242, so as to adjust the elastic acting force of the first elastic member 242.

[0036] Specifically, the second clamping structure 24b is a convex block fixed on the surrounding edge 231 and protruding above the supporting portion 232. In this way, the structure of the second clamping structure 24b is relatively simple, and it can abut against the longitudinal end surface of the glass slide to serve as a reference position when the glass slide is placed on the supporting portion 232.

[0037] Specifically, the first clamping structure 24a has a first abutting surface 248 that abuts against the glass slide, and the second clamping structure 24b has a second abutting surface 249 that abuts against the glass slide. Both the first abutting surface 248 and the second abutting surface 249 are inclined surfaces. The first abutting surface 248 and the second abutting surface 249 cooperate to apply a clamping force along the longitudinal direction of the glass slide and a pressing force to press the glass slide onto the supporting portion 232. It can be understood that both the first abutting surface 248 and the second abutting surface 249 are inclined surfaces that incline towards the supporting portion 232. In this way, when the first abutting surface 248 and the second abutting surface 249 jointly clamp the glass slide, the first abutting surface 248 and the second abutting surface 249 apply clamping forces in opposite directions along the longitudinal direction of the glass slide to the glass slide, and at the same time, the first abutting surface 248 and the second abutting surface 249 can also apply a pressing force towards the supporting portion 232 to the glass slide, so as to fix the glass slide at a fixed position on the supporting portion 232. Further, the inclination angles of the first abutting surface 248 and the second abutting surface 249 are 30° to 80°, that is, the angles between the first abutting surface 248 and the second abutting surface 249 and the plane where the supporting portion 232 is located are 30° to 80°. Within this angle range, the two abutting surfaces can balance the clamping force and the pressing force.

[0038] Specifically, the main body 23 includes two stoppers 238 arranged at intervals. The two stoppers 238 respectively correspond to the two lateral sides of the glass slide, and limit the glass slide in the transverse direction, thereby defining the installation position of the glass slide between the two stoppers 238. Further, a plurality of stoppers 238 are arranged at intervals in the transverse direction, and the installation position of the glass slide is defined between any two adjacent stoppers 238, so that a plurality of glass slides can be sequentially placed on the main body 23, and any two adjacent glass slides are separated by the stoppers 238. Further, the hollow area 234 on the support portion 232 corresponds to the specimen areas on a plurality of glass slides at the same time, and at this time the stopper 238 is arranged on the support portion 232. In this way, the entire hollow area 234 only corresponds to the specimen area of the glass slide, so that the specimen can be better compared and analyzed to avoid being affected by any other structure. Further, for the installation positions of a plurality of glass slides defined by a plurality of stoppers 238, a clamping assembly 24 and a picking and placing operation position 233 are correspondingly configured for any one installation position, so as to facilitate the picking and placing operation and clamping operation of the glass slide at this installation position.

[0039] In some embodiments, the glass slide rack 22 includes a first magnetic attraction member 25, and the first magnetic attraction member 25 is installed on the main body 23. A second magnetic attraction member (not shown) is installed on the scanning platform 120. The first magnetic attraction member 25 can be magnetically attracted to the second magnetic attraction member. Thus, after the conveying mechanism 31 conveys the glass slide rack 22 to the scanning platform 120, through the magnetic attraction between the first magnetic attraction member 25 and the second magnetic attraction member, the glass slide rack 22 can be quickly limited to a specific position on the scanning platform 120, thereby preventing the position of the glass slide rack 22 from changing when the microscope assembly 110 scans and analyzes the glass slides on the glass slide rack 22. Specifically, one of the first magnetic attraction member 25 and the second magnetic attraction member is a magnet, and the other is a magnetic conductor that can be magnetically attracted by the magnet, or both the first magnetic attraction member 25 and the second magnetic attraction member are magnets.

[0040] Combined with Figures 2 to 5 As shown, in some embodiments, a limiting hole 231a is formed on the surrounding edge 231. The glass slide basket 26 includes a card slot 27 and a limiting member 28 installed in the card slot 27. The limiting member 28 can be engaged with the limiting hole 231a to lock the glass slide rack 22 in the card slot 27. Through the mutual cooperation of the limiting hole 231a and the card slot 27, the glass slide rack 22 can be locked after being installed in the glass slide basket 26, so as to prevent the glass slide rack 22 from falling out of the glass slide basket 26 due to the inclination of the glass slide basket 26 during the transportation of the glass slide basket 26.

[0041] Combined with Figure 2 、 Figure 3 and Figure 7As shown, in some embodiments, a card slot 231b is formed on the surrounding edge 231. The conveying mechanism 31 includes a dragging component 34 which has a hook 342. The hook 342 can be engaged with the card slot 231b. Driven by the dragging component 34, the slide rack 22 is dragged to the scanning platform 120, thereby realizing the automatic transportation of the slide rack 22 from the slide basket 26 to the scanning platform 120.

[0042] Combined with Figure 4 and Figure 5 As shown, specifically in this embodiment, the slide basket 26 includes a card bin 27 and a limiting member 28. A card position 271 for accommodating the slide rack 22 is provided inside the card bin 27. The limiting member 28 is installed inside the card bin 27. The limiting member 28 includes a connecting portion 281 and a limiting portion 282 connected to the connecting portion 281. The limiting member 28 can move relative to the card bin 27 and has an unlocking state and a locking state. In the unlocking state, the limiting portion 282 is misaligned with the card position 271; in the locking state, the limiting portion 282 is aligned with the card position 271.

[0043] When the limiting member 28 is in the unlocking state, the slide rack 22 can be placed into or taken out of the card bin 27, so that the slide rack 22 can be introduced into or exported from the card position 271; when the limiting member 28 is in the locking state, the limiting portion 282 can be engaged with the limiting hole 231a on the slide rack 22 to lock the slide rack 22 on the card position 271, thereby preventing the slide rack 22 from sliding out of the slide basket 26 during the transportation of the slide basket 26.

[0044] Specifically, the card position 271 extends in the horizontal direction and has a starting end and a terminal end opposite to the starting end. The slide rack 22 is introduced into the card position 271 from the starting end and is installed in place when it moves to the terminal end. The limiting member 28 is located on one side of the terminal end so as not to affect the introduction or export of the slide rack 22, and can also lock the slide rack 22 when the slide rack 22 is installed in place. The limiting member 28 can move relative to the card bin 27 in the vertical direction to switch between the unlocking state and the locking state.

[0045] Further, a plurality of card positions 271 are sequentially arranged in the vertical direction inside the card bin 27. There are a plurality of limiting portions 282. The plurality of limiting portions 282 are spaced apart in the vertical direction and correspond to the plurality of card positions 271 one by one. By providing a plurality of card positions 271, a plurality of slide racks 22 can be sequentially placed in the vertical direction inside the card bin 27, thereby realizing the neat placement of the slide racks 22. The plurality of limiting portions 282 can correspond to the slide racks 22 placed at the card positions 271 one by one. During the movement of the limiting member 28, the plurality of limiting portions 282 can act simultaneously to unlock or lock the plurality of slide racks 22 synchronously, thereby improving the operation efficiency.

[0046] It should be noted that support bars 272 are correspondingly installed on the two opposite inner wall surfaces in the cartridge 27, and the two support bars 272 support the slide holder 22. There is a receiving space above the support bars 272 that exceeds the volume of the slide holder 22, and the part of the receiving space that can be used to accommodate the slide holder 22 is the clamping position 271. Therefore, when the limiting part 282 is aligned with the clamping position 271, it can be engaged with the limiting hole 231a on the slide holder 22 to present a locked state, and when the limiting part 282 is misaligned with the clamping position 271, it presents an unlocked state.

[0047] Specifically, the connecting part 281 has a rod-like structure, and the limiting part 282 extends circumferentially along the connecting part 281 to form a ring shape. A plurality of limiting parts 282 are arranged at intervals along the axial direction of the connecting part 281, so that the limiting member 28 has a rod structure with alternating thicknesses. Further, the limiting hole 231a on the slide holder 22 extends radially and penetrates the slide holder 22 to have a notch. It can be understood that the limiting hole 231a penetrates the slide holder 22 along the thickness direction of the slide holder 22 and extends radially along the limiting hole 231a to the edge of the slide holder 22, so that the limiting hole 231a has a notch. The diameter of the connecting part 281 is smaller than the diameter of the notch, and the diameter of the limiting part 282 is larger than the diameter of the notch. In this way, when the limiting member 28 is in the unlocked state, the limiting part 282 is misaligned with the clamping position 271, and the connecting part 281 can enter or exit the limiting hole 231a through the notch, so that the slide holder 22 can be inserted into or removed from the clamping position 271; after the slide holder 22 is inserted into the clamping position 271, by moving the limiting member 28 in the vertical direction, the limiting part 282 enters the limiting hole 231a, and since the limiting part 282 cannot be exported through the notch, the locking of the slide holder 22 by the limiting member 28 is realized.

[0048] Specifically, the cartridge 27 has a top surface 273 and a bottom surface 274 opposite to the top surface 273. The connecting part 281 has a rod-like structure, and one end thereof penetrates and protrudes from the bottom surface 274. When the bottom surface 274 is placed on the placement platform, the placement platform abuts against the connecting part 281 to make the limiting member 28 in the unlocked state. In this way, when the slide basket 26 is placed on the placement platform, since the placement platform contacts the connecting part 281 first and applies a holding force to the connecting part 281, the limiting member 28 moves relative to the cartridge 27 until the limiting member 28 and the bottom surface 274 of the cartridge 27 contact the placement platform together. At this time, the slide basket 26 is stably placed on the placement platform. During this process, the placement platform provides a force to the limiting member 28, so that the limiting member 28 is converted from the locked state to the unlocked state, facilitating the operator to take out or put in the slide holder 22 in the slide basket 26. It can be understood that the placement platform can be a specially set platform for placing the slide basket 26, or can be understood as the ground.

[0049] Specifically, the slide basket 26 includes an elastic member 29, and the elastic member 29 abuts against the limiting member 28 to provide a force for the limiting member 28 to switch from the unlocked state to the locked state. When the slide basket 26 is lifted from the storage platform, since the force of the storage platform on the limiting member 28 disappears, under the elastic action of the elastic member 29, the limiting member 28 can be forced to move relative to the cartridge 27 and finally present a locked state to lock the slide holder 22 to the slide basket 26. In this way, without any specific operation by the operator, the limiting member 28 can be automatically switched to the required state according to the needs of the use environment, so that the structure of the slide basket 26 has the function of automatically locking and unlocking the slide holder 22, and the overall structure is simple and easy to use.

[0050] Specifically, the elastic member 29 is a spring disposed on the top surface 273. One end of the spring abuts against the top surface 273, and the other end abuts against the limiting member 28 to apply an elastic thrust force towards the bottom surface 274 to the limiting member 28. In other embodiments, the elastic member 29 is a tension spring disposed on the bottom surface 274. One end of the tension spring is connected to the bottom surface 274, and the other end is connected to the limiting member 28 to apply an elastic pulling force towards the bottom surface 274 to the limiting member 28. Therefore, only by making the elastic member 29 apply an elastic force towards the bottom surface 274 to the limiting member 28, the limiting member 28 can be automatically reset to the locked state when the slide basket 26 is lifted. It should be noted that in other embodiments, the elastic member 29 can also be omitted. At this time, the gravity of the limiting member 28 itself enables the limiting member 28 to move relative to the cartridge 27 to provide a force for the state transition of the limiting member 28 from the unlocked state to the locked state.

[0051] Combined with Figure 6 and Figure 7As shown, in some embodiments, the conveying mechanism 31 is used to convey the glass slides. Specifically, since a plurality of slide holders 22 are carried in the slide basket 26, at this time, the conveying mechanism 31 can convey the slide holders 22 in the slide basket 26 to the scanning platform 120 one by one. Specifically, the conveying mechanism 31 includes a first driving assembly 32, a second driving assembly 33, and a dragging assembly 34. Among them, the first driving assembly 32 is used to support the slide basket 26 and drive the slide basket 26 to move up and down so that the slide basket 26 moves to the target height. The second driving assembly 33 is connected to the scanning platform 120 to drive the scanning platform 120 to move, so that the scanning platform 120 moves relative to the microscope assembly 110. The first driving assembly 32, under the mutual cooperation of the first driving assembly 32 and the second driving assembly 33, can align the scanning platform 120 with the clamping position 271 on the slide basket 26. The dragging assembly 34 can engage with the slide holder 22 in the slide basket 26, and when the clamping position 271 in the slide basket 26 is aligned with the scanning platform 120, drag the slide holder 22 onto the scanning platform 120, or drag the slide holder 22 from the scanning platform 120 to the slide basket 26. In this way, through the mutual cooperation of the components in the conveying mechanism 31, the slide holder 22 can be smoothly dragged from the slide basket 26 onto the scanning platform 120 and move to the lower field of view of the microscope assembly 110, and can be smoothly dragged back into the slide basket 26 after the detection. During the whole process, the slide holder 22 can be smoothly supported without problems such as dropping and damaging the specimen, thereby realizing the smooth conveyance of the slide holder 22.

[0052] Specifically, the first driving assembly 32 includes a placement platform 321 and a first driving structure 322. The placement platform 321 is used to carry the slide basket 26, and the first driving structure 322 is connected to the placement platform 321 to drive the placement platform 321 to move up and down. By aligning the scanning platform 120 with the clamping positions 271 at different heights in the slide basket 26, the conveyance of the slide holders 22 installed on different clamping positions 271 can be realized. In addition, the first driving assembly 32 provides a placement platform 321 for the slide basket 26. After the slide basket 26 is placed on the placement platform 321, the placement platform 321 acts on the limiting member 28 to unlock the limiting member 28, which is beneficial for the dragging assembly 34 to take out the slide holder 22 from the slide basket 26 and transport the slide holder 22 onto the scanning platform 120, or drag the slide holder 22 on the scanning platform 120 back into the slide basket 26. Further, the first driving structure 322 is a linear translation structure composed of a support 322a, a motor 322b, a lead screw 322c, and a slider 322d cooperating with each other. Specifically, the placement platform 321 is connected to the slider 322d. In other embodiments, the first driving structure 322 can also be an electric cylinder, a pneumatic / hydraulic cylinder, a belt drive, a chain drive, or other driving structures capable of realizing linear translation.

[0053] Specifically, the second driving assembly 33 includes a second driving structure 331 and a sliding platform 332. The scanning platform 120 is slidably connected to the sliding platform 332 and slides relative to the frame along a first direction under the drive of the second driving structure 331, where the first direction is the direction of approaching or departing from the slide basket 26. In this way, under the drive of the second driving structure 331, the scanning platform 120 slides relative to the sliding platform 332 and approaches the slide basket 26 to align with the clamping position 271.

[0054] Furthermore, the second driving assembly 33 includes a frame 333. The sliding platform 332 is slidably connected to the frame 333 and slides relative to the frame 333 along a second direction under the drive of the second driving structure 331, where there is an included angle between the second direction and the first direction. It can be understood that under the drive of the second driving structure 331, the sliding platform 332 drives the scanning platform 120 to move relative to the frame 333 along the second direction. In this way, the scanning platform 120 can not only move relative to the microscope assembly 110 in the first direction, but also move relative to the microscope assembly 110 along the second direction, so that the specimen on the slide can be directly opposite the microscope assembly 110, which helps the microscope assembly 110 better analyze and detect the slide on the scanning platform 120. Specifically, in the present application, the first direction and the second direction are two directions perpendicular to each other on a horizontal plane. For example, if the first direction is the X-axis direction in a coordinate system, then the second direction is the Y-axis direction in the coordinate system. The second driving structure 331 can be an electric cylinder, a pneumatic / hydraulic cylinder, a belt drive, a chain drive, or other driving structures capable of realizing linear translation, or a combination of multiple linear translation driving structures, so as to achieve the purpose of enabling the scanning platform 120 to translate in multiple directions.

[0055] Specifically, the dragging assembly 34 includes a third driving structure 341 and a hook 342. The third driving structure 341 is connected to the hook 342 and drives the hook 342 to move along the first direction. In this way, when the hook 342 is engaged with the slot 231b on the slide holder 22, the hook 342 drives the slide holder 22 to move along the first direction due to the third driving structure 341 driving the hook 342 to move along the first direction, thereby realizing the dragging of the slide holder 22.

[0056] Further, the hook 342 includes a connecting body 342a and a hook body 342b. The connecting body 342a has a rod-shaped structure. The shape of the hook body 342b is adapted to the shape of the card slot 231b and can abut against the inner wall surface of the card slot 231b in the first direction. It can be understood that after the hook 342 is received in the card slot 231b, the hook 342 abuts against the inner wall surface of the card slot 231b in the first direction, so as to realize the dragging of the slide holder 22 by the hook 342. Specifically, the hook body 342b includes a connecting section and a clamping section. One end of the connecting section is connected to the connecting body 342a, and the clamping section is horizontally disposed at the other end of the connecting section. The connecting section and the clamping section cooperate together to make the hook body 342b have a "T" - shaped structure. In other embodiments, the hook body 342b can also have an "L" - shaped structure. In addition, the end face area of the connecting section is smaller than the end face area of the connecting body 342a, so that the hook 342 has an "I" - shaped structure. With such a setting, when the dragging component 34 pushes the slide holder 22 from the scanning platform 120 back into the slide basket 26, the end face of the connecting body 342a can abut against the outer wall surface of the slide holder 22, and also exert a pushing force on the slide holder 22 to ensure the smooth movement of the slide holder 22.

[0057] Specifically, the third driving structure 341 and the first driving component 32 cooperate together to make the hook 342 engage with the card slot 231b. It can be understood that when the first driving component 32 drives the slide holder 22 to rise to the target height, the third driving structure 341 drives the hook 342 to move in the first direction, so as to be positioned directly above or directly below the card slot 231b. Then, by driving the slide holder 22 to move by the first driving component 32, the hook 342 is exactly received in the card slot 231b to achieve engagement with the card slot 231b.

[0058] Specifically, the dragging component 34 is installed on the scanning platform 120. The dragging component 34 can move synchronously with the scanning platform 120. With such a setting, when the second driving structure 331 drives the scanning platform 120 to move in the first direction, the scanning platform 120 drives the dragging component 34 to move synchronously. When the scanning platform 120 is aligned with the card position 271 in the slide basket 26, the third driving structure 341 acts to realize the dragging of the slide holder 22 by the hook 342. In this way, the driving stroke of the third driving structure 341 can be greatly shortened, which helps to improve the movement smoothness of the hook 342. Among them, the third driving structure 341 is a linear translation structure composed of a support 341a, a motor 341b, a lead screw 341c and a slider 341d. Specifically, the hook 342 is connected to the slider 341d. In other embodiments, the third driving structure 341 can also be an electric cylinder, a pneumatic / hydraulic cylinder, a belt drive, a chain drive or other driving structures that can realize linear translation.

[0059] Such as Figure 8As shown, in some embodiments, the oil dropping mechanism 41 includes an oil bottle 42, an oil pump (not shown), and an oil dropping needle (not shown). The oil bottle 42 is used to store the mirror oil. The oil pump is connected between the oil dropping needle and the oil bottle 42 to pump the mirror oil in the oil bottle 42 to the oil dropping needle. The oil dropping needle points into the field of view of the microscope assembly 110 and is used to drop the mirror oil onto the glass slide on the scanning platform 120 within the field of view of the microscope assembly 110.

[0060] Specifically, the oil dropping mechanism 41 includes a detection component 43 connected to the oil bottle 42. The detection component 43 is disposed outside the oil bottle 42. The detection component 43 can detect the weight of the oil bottle 42 in real time and obtain the parameters of the remaining mirror oil in the oil bottle 42. By providing the detection component 43, the content of the remaining mirror oil in the oil bottle 42 can be quantitatively detected. According to this parameter, the operator can directly determine whether the oil bottle 42 needs to be filled with mirror oil, so as to accurately grasp the refueling time. In addition, compared with the solutions of detecting the liquid level of the mirror oil in the oil bottle 42 to judge the remaining oil volume, observing whether there are bubbles in the transmission oil pipe to judge whether the mirror oil is used up, calculating the oil consumption per oil drop to estimate the remaining oil volume, and using ultrasonic waves to detect the remaining oil volume, the solution of using the detection component 43 to detect the weight of the oil bottle 42 has at least the following advantages: it does not need to contact the mirror oil in the oil bottle 42, thus ensuring the cleanliness of the mirror oil and avoiding contamination of the mirror oil; the detection efficiency is relatively high; the detection accuracy is relatively high; the structure is simple and the cost is low.

[0061] Specifically, the detection component 43 includes a sensor 43a. The sensor 43a includes a substrate 431 and a sensing body 432 mounted on the substrate 431. The oil bottle 42 is mounted on the sensing body 432. The substrate 431 serves as a support structure for the sensing body 432 to provide stable horizontal support for the sensing body 432 and the oil bottle 42. Further, the sensor 43a is a weighing sensor, and the weighing sensor can weigh the oil bottle 42 placed thereon to obtain the weight of the oil bottle 42 in real time.

[0062] Further, the detection component 43 further includes a calculation module (not shown), and the calculation module is connected to the sensor 43a to calculate the parameter K of the remaining mirror oil in the oil bottle 42, and K = (m3 - m1) / (m2 - m1), where when there is no mirror oil in the oil bottle 42, the weight of the oil bottle 42 detected by the detection component 43 is m1; when the oil bottle 42 is full of mirror oil, the weight of the oil bottle 42 detected by the detection component 43 is m2; the weight of the oil bottle 42 detected by the detection component 43 in real time is m3. It can be understood that the value of (m3 - m1) is the weight of the remaining mirror oil in the oil bottle 42, the value of (m2 - m1) is the total weight of the mirror oil when the oil bottle 42 is full of mirror oil, and K is the ratio of the remaining mirror oil to the total weight of the mirror oil when it is full. For example, when the detection component 43 detects that m1 is 10 g, m2 is 20 g, and m3 is 12 g, it means that 2 g of the mirror oil with a total weight of 10 g remains. At this time, the parameter K of the remaining mirror oil is 20%.

[0063] Specifically, the sensor 43a includes a mounting base 433, and the mounting base 433 is connected to the sensor main body 432. The sensor main body 432 is located between the mounting base 433 and the substrate 431. A mounting groove (not labeled in the figure) is formed on the mounting base 433, and at least part of the oil bottle 42 is placed in the mounting groove. Placing the oil bottle 42 in the mounting groove can form a fixed mounting position for the oil bottle 42, and at the same time can ensure the stable position of the oil bottle 42 relative to the sensor main body 432. Moreover, when it is necessary to add oil to the oil bottle 42, the oil bottle 42 can be taken out of the mounting groove, so that the connection between the oil bottle 42 and the sensor main body 432 is simple and reliable.

[0064] Specifically, the capacity of the oil bottle 42 is 250 ml. The large-capacity oil bottle 42 can store more mirror oil and can be used for detecting a larger number of glass slides.

[0065] Specifically, the sample scanner 10 includes a control center (not shown in the figure). The detection component 43 is connected to the control center and sends the parameters of the remaining mirror oil in the oil bottle 42 to the control center. When the parameters are less than the established value, the control center issues a warning prompt. In this way, the operator can refuel the oil bottle 42 according to the warning prompt issued by the control center, thus avoiding the problem that the operator needs to check the remaining mirror oil in the oil bottle 42 irregularly and preventing the operator from forgetting to replace the mirror oil. Further, the established value is set to 20%. It can be understood that when the parameter K of the remaining mirror oil in the oil bottle 42 is less than 20%, the control center will issue a warning prompt to remind the operator to perform the refueling operation. In addition, the sample scanner 10 includes a display (not shown in the figure). The display is connected to the control center, and the display shows the parameters of the remaining mirror oil in the oil bottle 42 and the warning prompt issued by the control center. For example, the display shows the parameters of the remaining mirror oil, and the parameter K value can be intuitively seen through the display to fully grasp the remaining oil volume in the oil bottle 42. When the parameter K value is lower than the set established value, the parameter K value issues a warning prompt by continuously flashing in an abnormal color or an abnormal icon, thereby reminding the operator to perform the refueling operation.

[0066] In the above sample scanner 10, by the mutual cooperation of the conveying mechanism 31 and the cartridge mechanism 21, the slide holder 22 carrying the slide can be automatically and smoothly transferred between the slide basket 26 and the scanning platform 120, without manually loading the slide on the scanning platform 120. This not only improves the sample processing efficiency but also effectively ensures the safety of the transfer, preventing the slide from being damaged or the specimen from being contaminated.

[0067] The technical features of the above-described embodiments can be combined arbitrarily. For the sake of brevity of description, not all possible combinations of the technical features in the above-described embodiments are described. However, as long as there is no contradiction in the combination of these technical features, it should be considered as within the scope described in this specification.

[0068] The above-described embodiments merely represent several implementation manners of the present invention. The description is relatively specific and detailed, but it should not be construed as a limitation on the scope of the invention patent. It should be noted that for those of ordinary skill in the art, without departing from the concept of the present invention, several modifications and improvements can still be made, and these all belong to the protection scope of the present invention. Therefore, the protection scope of the present invention patent shall be subject to the appended claims.

Claims

1. A slide basket, characterized in that, The slide basket includes: A card bin, inside which there are positions for accommodating slide racks; and A limiting member, which is installed inside the card bin, and the limiting member includes a connecting portion and a limiting portion connected to the connecting portion; Wherein, the limiting member can move relative to the card bin and has an unlocked state and a locked state; in the unlocked state, the limiting portion is misaligned with the limiting hole on the slide rack; in the locked state, the limiting portion is engaged with the limiting hole on the slide rack; the card bin has a top surface and a bottom surface opposite to the top surface, the connecting portion is in a rod-shaped structure, and one end of it penetrates and protrudes from the bottom surface; the limiting portion extends circumferentially along the connecting portion to form a ring shape; the limiting portions are arranged at intervals along the axial direction of the connecting portion; when the bottom surface is placed on the placing platform, the placing platform abuts against the connecting portion, and the connecting portion moves upward, so that the limiting member is in the unlocked state.

2. The slide basket according to claim 1, characterized in that, The position extends horizontally and has a starting end and a terminal end opposite to the starting end, the limiting member is located on one side of the terminal end, and the limiting member can move relative to the card bin in the vertical direction.

3. The slide basket according to claim 2, wherein, A plurality of the positions are sequentially arranged in the card bin in the vertical direction, there are a plurality of the limiting portions, and the plurality of limiting portions are arranged at intervals in the vertical direction and correspond to the plurality of positions one by one.

4. The slide basket according to claim 1, characterized in that, The slide basket includes an elastic member, and the elastic member abuts against the limiting member to provide a force for the limiting member to switch from the unlocked state to the locked state.

5. The slide basket according to claim 4, wherein The elastic member is a spring arranged on the top surface, one end of the spring abuts against the top surface, and the other end abuts against the limiting member to apply an elastic thrust force towards the bottom surface to the limiting member; or, the elastic member is a tension spring arranged on the bottom surface, one end of the tension spring is connected to the bottom surface, and the other end is connected to the limiting member to apply an elastic pulling force towards the bottom surface to the limiting member.

6. A sample analyzer, characterized in that, Including: The slide basket according to any one of claims 1 to 5; A slide rack, on which a limiting hole is opened; And A microscope mechanism, which is used to detect the sample on the slide rack; Wherein, when the limiting member is in the unlocked state, the limiting portion is misaligned with the limiting hole on the slide rack, and the slide rack can be inserted into or taken out from the position; When the limiting member is in the locked state, the limiting portion is engaged with the limiting hole to lock the slide rack in the position.

7. The sample analyzer according to claim 6, wherein, The limiting hole extends radially through the slide rack and has a notch; the connecting portion is in a rod-shaped structure, the limiting portion extends circumferentially along the connecting portion to form a ring shape; the diameter of the connecting portion is smaller than the diameter of the notch, and the diameter of the limiting portion is larger than the diameter of the notch.

8. The sample analyzer according to claim 7, characterized in that, The sample analyzer further includes a conveying mechanism; the microscope mechanism includes a scanning platform and a microscope assembly suspended above the scanning platform; the slide basket is installed on the conveying mechanism, and the conveying mechanism can convey the slide rack installed in the slide basket to the scanning platform.

Images