Flow path holding device and liquid processing apparatus

Abstract

This invention provides a flow path holding device and a liquid handling device for preventing breakage and detachment of a heating plate engaged with a frame-shaped body in a flow path holding device. The flow path holding device includes: a heating plate for heating a liquid flowing in a heated flow path; a frame-shaped body having an opening on its inner side, the frame-shaped body engaging with the heating plate such that the heating plate is positioned at the opening; a pressing member for pressing the heating plate to prevent it from detaching from the frame-shaped body; a first engaging mechanism for engaging the heating plate and the frame-shaped body in a manner that restricts movement of the heating plate relative to the frame-shaped body along the surface direction (X) and in a vertical direction (Z) perpendicular to the surface direction during engagement; and a second engaging mechanism for engaging the heating plate and the frame-shaped body at a different position from the first engaging mechanism, in a manner that restricts movement of the heating plate relative to the frame-shaped body along the surface direction of the heating plate while allowing movement of the heating plate in the vertical direction (Z) during engagement.

Description

Technical Field

[0001] This invention relates to flow path holding devices and liquid handling devices. Background Technology

[0002] Extracorporeal circulation therapies such as dialysis and plasma exchange have always been performed using blood purification devices. Such blood purification devices, for example, include a blood purification circuit that supplies the patient's blood to a blood purifier for purification and returns it to the patient's blood, and a rehydration circuit that replenishes the blood with rehydration fluid (see Patent Document 1). For example, since the rehydration fluid delivered to the patient needs to be heated to a specified temperature range, a heating flow path for heating the rehydration fluid is provided in the rehydration circuit.

[0003] Furthermore, the liquid flow path used in the aforementioned blood purification device, which includes a heating flow path, is a complex flow path composed of multiple systems. It is time-consuming and cumbersome for medical personnel to install all the liquid flow paths onto the device body each time. Therefore, a flow path holding device (see Patent Document 2) has been proposed to uniformly hold a portion of the liquid flow path, including the heating flow path, so that a portion of the liquid flow path can be uniformly installed onto the device body.

[0004] Such a flow path holding device includes, for example, a heating plate having a heating flow path, and a frame-like body that holds the heating plate (see Patent Documents 2 and 3).

[0005] Prior art literature

[0006] Patent documents

[0007] Patent Document 1: Japanese Patent No. 5160455

[0008] Patent Document 2: Japanese Patent Application Publication No. 2015-073847

[0009] Patent Document 3: Japanese Patent Application Publication No. 2020-14726 Summary of the Invention

[0010] The problem the invention aims to solve

[0011] However, in the aforementioned flow path holding device, when external forces are applied, such as during transport, the frame may bend, potentially causing the heating plate to deform and break. In particular, when the heating plate is under low-temperature conditions, it becomes brittle and easily breaks during transport. Furthermore, when the frame bends, the heating plate may detach from the frame.

[0012] The present invention was made in view of this point, and one of its objectives is to provide a flow path holding device and a liquid handling device capable of suppressing the breakage or detachment of the heating plate engaged with the frame in the flow path holding device.

[0013] Solutions for solving problems

[0014] The inventors conducted in-depth research and found that, when the heating plate is engaged with the frame, the above-mentioned problem can be solved by allowing the heating plate to move vertically relative to the frame, thus completing the present invention.

[0015] That is, the present invention includes the following technical solutions.

[0016] (1) A flow path holding device for holding a liquid flow path, wherein the flow path holding device comprises: a heating plate having a heating flow path for heating a liquid flowing in the heating flow path; a frame-shaped body having an opening on its inner side, the frame-shaped body engaging with the heating plate such that the heating plate is disposed in the opening; a pressing member pressing the heating plate so that it does not disengage from the frame-shaped body; a first engaging mechanism engaging the heating plate and the frame-shaped body in such a way that, when engaged, the movement of the heating plate relative to the frame-shaped body along the surface direction of the heating plate and in a vertical direction perpendicular to the surface direction of the heating plate is restricted.; and a second engaging mechanism engaging the heating plate and the frame-shaped body at a different position from the first engaging mechanism in such a way that, when engaged, the movement of the heating plate relative to the frame-shaped body along the surface direction of the heating plate is restricted and the movement of the heating plate in the vertical direction is permitted.

[0017] (2) The flow path holding device according to (1), wherein the second engaging mechanism is composed of a protrusion and a frame-shaped portion, the protrusion being formed on the frame-shaped frame and extending along the vertical direction, the frame-shaped portion being formed on the heating plate, and a hole for the protrusion to pass through is formed in the frame-shaped portion.

[0018] (3) The flow path holding device according to (1) or (2), wherein the first engaging mechanism is composed of a hook and a frame, the hook being formed on the frame and the frame being formed on the heating plate, and a hole being formed in the frame to engage with the hook.

[0019] (4) The flow path holding device according to any one of (1) to (3), wherein the first engaging mechanism is provided on the first outer edge of the heating plate, and the second engaging mechanism is provided on the second outer edge of the heating plate opposite to the first outer edge.

[0020] (5) The flow path holding device according to (4), wherein the second engaging mechanism is located at the center of the edge direction of the second outer edge of the heating plate.

[0021] (6) The flow path holding device according to (4) or (5), wherein the first engaging mechanism is provided at least at both ends of the first outer edge of the heating plate in the edge direction.

[0022] (7) The flow path holding device according to any one of (1) to (6), wherein the pressing member has a plate shape covering the heating plate.

[0023] (8) The flow path holding device according to any one of (1) to (7), wherein the pressing member presses the heating plate relative to the frame-shaped frame so that the engagement between the heating plate and the frame-shaped frame based on the first engagement mechanism and the second engagement mechanism will not disengage.

[0024] (9) The flow path holding device according to any one of (1) to (8), wherein the pressing member is locked to the frame-shaped frame.

[0025] (10) The flow path holding device according to (9), wherein the frame has: a locking part that locks the pressing member; and a limiting part that limits the pressing member from disengaging from the locking part.

[0026] (11) The flow path holding device according to any one of (1) to (10), wherein the liquid flow path has a tube having a connection area connected to the heating flow path of the heating plate, the connection area being disposed on the frame-like body, and the pressing member having a pressing portion pressing the connection area of ​​the tube relative to the frame-like body.

[0027] (12) The flow path holding device according to any one of (1) to (11), wherein the heating plate is made of vinyl chloride.

[0028] (13) A liquid processing apparatus, wherein the liquid processing apparatus comprises a flow path holding device as described in any one of (1) to (12) and a device body for free mounting of the flow path holding device.

[0029] The effects of the invention

[0030] According to the present invention, it is possible to suppress the breakage or detachment of the heating plate that engages with the frame in the flow path holding device. Attached Figure Description

[0031] Figure 1 This is a perspective view showing an example of a blood purification device.

[0032] Figure 2 This is an illustrative diagram showing an example of the structure of a liquid circuit.

[0033] Figure 3This is the front view of the frame-like structure with the heating plate and pressing component installed.

[0034] Figure 4 This is the front view of the frame-like structure with the heating plate installed.

[0035] Figure 5 This is the front view representing the frame-like structure.

[0036] Figure 6 This is an explanatory diagram showing the first locking mechanism.

[0037] Figure 7 This is an explanatory diagram showing the second locking mechanism.

[0038] Figure 8 This is an explanatory diagram showing the locking mechanism between the pressing component and the frame-shaped body.

[0039] Figure 9 This is the front view of the heating plate.

[0040] Figure 10 This is the front view of the pressing component.

[0041] Figure 11 This is an explanatory diagram showing the structure of the metering chamber.

[0042] Figure 12 This is the front view of another type of frame-like structure.

[0043] Explanation of reference numerals in the attached figures

[0044] 1. Blood purification device; 40. Flow path holding device; 50. Heating plate; 51. Frame-shaped body; 52. Pressing component; 53. Metering chamber; 54. Tube; 350. First locking mechanism; 351. Second locking mechanism; 360. Locking mechanism; X, plane direction; Z, vertical direction. Detailed Implementation

[0045] Hereinafter, an example of a preferred embodiment of the present invention will be described with reference to the accompanying drawings. Furthermore, unless otherwise specified, the positional relationships such as top, bottom, left, and right in the drawings are considered to be based on the positional relationships shown in the drawings. The scale ratios in the drawings are not limited to those shown. Moreover, the following embodiments are illustrative of the present invention and are not intended to limit the present invention to the spirit of the following embodiments. Furthermore, various modifications can be made to the present invention without departing from its spirit.

[0046] <Blood Purification Device>

[0047] Figure 1This is an explanatory diagram showing the schematic structure of a blood purification device 1, which is a liquid processing device and includes the flow path holding device of this embodiment. The blood purification device 1 includes, for example, a device body 10, an operation panel 11, a trolley 12, a lever 13, and a liquid circuit 14.

[0048] The main body 10 of the device is configured to house or install various devices, apparatuses, and components required for performing blood processing. For example, the following components can be housed or installed in the main body 10: various gate groups 20 for opening and closing the flow path in the liquid circuit 14; a pump group 21 for conveying liquid in the liquid circuit 14 by pressure; a pressure sensor (not shown) for detecting the liquid pressure in the liquid circuit 14; and a blood purifier (described later) for purifying the blood. A door 30 is provided on the side of the main body 10, and the portion exposed when the door 30 is opened becomes an assembly part 33 for assembling the flow path holding device 40 of the liquid circuit 14. The assembly part 33 is provided with a flat heater 31 and a metering device 32. The flow path holding device 40 includes a heating plate 50, a frame-like body 51, a pressing member 52, a metering chamber 53, and a tube 54. By assembling the flow path holding device 40 on the assembly part 33 and supplying heat from the heater 31 to the heating plate 50, the liquid flowing in the heating plate 50 can be heated, and the weight of the metering chamber 53 can be measured using the metering device 32.

[0049] The operation panel 11 is, for example, a touchpad, through which various settings for blood processing can be input and the operating status of blood processing can be displayed. Infusion bags such as dialysis bags and rehydration bags, which are used for blood processing and will be described later, can be suspended from the rod 13.

[0050] <Liquid Circuit>

[0051] Figure 2 This is an explanatory diagram showing an example of the structure of a liquid circuit 14 used for dialysis treatment. For example, the liquid circuit 14 includes a blood purifier 70, a blood circuit 71, a dialysate supply path 72, a waste fluid path 73, and a replenishment path 74. The liquid circuit 14 is assembled to the main body 10 of the blood purification device 1 in a manner that allows for easy assembly and disassembly.

[0052] The blood purifier 70 is, for example, a cylindrical membrane assembly having a hollow fiber membrane as a purification membrane, which can be used to separate unwanted components from the blood.

[0053] The blood circuit 71 includes, for example, a blood collection path 90 connecting the blood collection unit 80 and the blood purifier 70, and a return path 91 connecting the blood purifier 70 and the return section 81. The blood collection path 90 and the return path 91 are primarily composed of tubing. The blood collection path 90 is connected to the inlet of the blood purifier 70, and the return path 91 is connected to the outlet of the blood purifier 70.

[0054] For example, a pressure delivery pump 100 is provided in the blood collection path 90. An infusion device 110 and a pressure sensor are provided in the return blood path 91.

[0055] The dialysate supply path 72 includes a dialysate bag 120 and a dialysate flow path 121 connecting the dialysate bag 120 and the dialysate side inlet of the blood purifier 70. The dialysate flow path 121 is mainly composed of tubing, but a portion of it consists of the liquid flow path of the heating plate 50 (described later) and the liquid flow path of the metering chamber 53. A dialysate pump 122 is provided in the dialysate flow path 121.

[0056] Waste liquid flow path 73 includes waste liquid flow path 130, which connects the dialysate side inlet and waste liquid section of the blood purifier 70. Waste liquid flow path 130 is mainly composed of tubing, but a portion of it is formed by the liquid flow path of metering chamber 53. A filter pump 131 is provided, for example, in waste liquid flow path 130.

[0057] The fluid resuscitation path 74 includes: a resuscitation bag 140; and a resuscitation path 141 connecting the resuscitation bag 140 and the return blood path 91. The resuscitation path 141 is mainly composed of tubing, but a portion of it consists of the liquid flow path of the heating plate 50 and the liquid flow path of the metering chamber 53. A resuscitation pump 142 is provided in the resuscitation path 141.

[0058] The aforementioned liquid circuit 14 can be used for blood purification processes, such as those used in dialysis treatment. For example, in the blood circuit 71, the patient's blood is transported from the blood collection section 80 to the blood side of the purification membrane of the blood purifier 70, and then returned to the patient from the return section 81 after passing through the blood purifier 70. At this time, in the dialysate supply path 72, dialysate is transported to the dialysate side of the purification membrane of the blood purifier 70, and then discarded via the waste liquid path 73. Using the blood purifier 70, unwanted components in the blood on the blood side of the purification membrane are allowed to flow through the purification membrane to the dialysate side and are discharged together with the dialysate. On the other hand, in the replenishment path 74, replenishment fluid is supplied to the blood circuit 71 to replenish the prescribed components into the blood.

[0059] <Flow path holding device>

[0060] like Figure 2As shown, the flow path holding device 40 is configured to hold at least a portion of the liquid circuit 14, namely at least a portion of the dialysate flow path 121, at least a portion of the waste liquid flow path 130, and at least a portion of the replenishment flow path 141, and is assembled to the main body 10 of the device in a manner that allows for easy assembly and disassembly. Furthermore, the extent to which the flow path holding device 40 holds any flow path in the liquid circuit 14 can be appropriately varied. The flow path holding device 40 includes, for example, a heating plate 50, a frame-like body 51, a pressing member 52, a metering chamber 53, and a tube 54 that is part of the liquid flow path.

[0061] Figure 3 This is a front view of the frame 51 on which the heating plate 50 and the pressing member 52 are installed. Figure 4 This is the front view of the frame 51 on which the heating plate 50 is installed. Figure 5 This represents the front view of the frame-like body 51. For example... Figures 3 to 5 As shown, the frame-like body 51 has a square plate shape and is made of rigid resin, such as ABS resin. The frame-like body 51 has an opening 160 in the center for mounting the heating plate 50. The opening 160 has a square shape. The frame-like body 51 is provided with a plurality of fixing parts 161 for fixing the tube 54. Furthermore, the arrangement and number of fixing parts 161 are not limited to... Figures 3 to 5 The configuration and quantity can be changed appropriately.

[0062] Above the opening 160 of the frame 51, in the upper part 51a, there is an upper hook 170 for locking the upper part of the heating plate 50 and the upper part of the pressing member 52. The upper hook 170 is provided at two locations on the upper part 51a, corresponding to the two ends of the opening 160 in the left-right direction (horizontal direction) X1. Figure 6 As shown, the upper hook portion 170 has: a first portion 170a, which extends in a vertical direction Z perpendicular to the surface direction X of the frame-like frame 51; and a second portion 170b, which connects to the top end of the first portion 170a and extends upward from that top end in a vertical direction X2 above the frame-like frame 51. Furthermore, in this specification, as... Figures 1 to 5 Thus, "up," "down," "left," and "right" are based on the posture when using the flow path holding device 40. In addition, "face direction X" in this embodiment includes X1 and X2.

[0063] like Figures 3 to 5 As shown, a protrusion 180 for securing the lower part of the heating plate 50 is provided in the lower part 51b below the opening 160 of the frame 51. The protrusion 180 is located in the lower part 51b at a position corresponding to the center of the opening 160 in the left-right direction X1. Figure 7 As shown, the protrusion 180 has a rod shape and extends along a vertical direction Z that is perpendicular to the surface direction X of the frame 51.

[0064] like Figures 3 to 5 As shown, a lower hook 190 for locking the lower part of the pressing member 52 is provided in the lower part 51b below the opening 160 of the frame 51. The lower hook 190 is provided at two locations corresponding to the two ends of the opening 160 in the left-right direction X1. Figure 8 As shown, the lower hook portion 190 has: a first portion 190a, which extends along a vertical direction Z perpendicular to the surface direction X of the frame 51; and a second portion 190b, which is connected to the top end of the first portion 190a and extends downward from the top end toward the frame 51 in the vertical direction X2.

[0065] like Figures 3 to 5 As shown, an upper limiting part 200 is provided on the upper part 51a of the frame-shaped body 51 to prevent the pressing member 52 from disengaging from the upper hook 170. The upper limiting part 200 is located above each upper hook 170, slightly offset from the center in the left-right direction X1 than each upper hook 170. The upper limiting part 200 has, for example, a... Figure 6 As shown, it has a plate shape that extends vertically in the Z direction and has its surface facing downwards. The upper limiting part 200 has, for example, a width in the left-right direction X1 that is the same as that of the upper hook part 170, or a width in the left-right direction X1 that is longer than that of the upper hook part 170.

[0066] like Figures 3 to 5 As shown, a lower limiting part 210 is provided at the lower part 51b of the frame 51 to prevent the pressing member 52 from disengaging from the lower hook 190. The lower limiting part 210 is located below each lower hook 190. The lower limiting part 210 has, for example, the following characteristics: Figure 8 As shown, it has a plate shape that extends vertically in the Z direction and has its surface facing upwards. The lower limiting part 210 has, for example, a width in the left-right direction X1 that is the same as that of the lower hook part 190, or a width in the left-right direction X1 that is longer than that of the lower hook part 190.

[0067] like Figure 3 , Figure 4 and Figure 9 As shown, the heating plate 50 has a generally rectangular, thin plate shape. The heating plate 50 is made of, for example, vinyl chloride, the same material as the tube 54. The heating plate 50 includes: a plate body portion 250 having a liquid flow path; and an upper frame-like portion 251 and a lower frame-like portion 252 for engaging the heating plate 50 with the frame-like frame 51.

[0068] like Figure 9As shown, the main body 250 is formed into a relatively thin rectangle. The main body 250 has two heating flow paths 262 that extend continuously from the inlet 260 to the outlet 261. The inlet 260 and outlet 261 are located on the upper short side of the main body 250 in the vertical direction X2. Each heating flow path 262 has: a serpentine portion 270 that extends downwards while serpentinely moving left and right from the inlet 260; and a straight portion 271 that extends directly from the lower part of the serpentine portion 270, passing beside the serpentine portion 270, and connecting to the outlet 261. The two heating flow paths 262 are arranged horizontally on the left and right sides of the main body 250. The inlet 260 and outlet 261 form a connecting portion for connecting the heating flow path 262 to the pipe 54. For example, a tube 54 of the dialysate flow path 121 is connected to a connection point of one heating flow path 262, and a tube 54 of the replenishment flow path 141 is connected to a connection point of another heating flow path 262. Thus, one heating flow path 262 constitutes a part of the dialysate flow path 121, and the other heating flow path 262 constitutes a part of the replenishment flow path 141. Furthermore, the portion of the tube 54 connected to the heating flow path 262 near the inlet 260 and outlet 261 forms the connection region 54a of the tube 54.

[0069] The upper frame-shaped portion 251 is provided, for example, on the upper edge portion 50a, which is the first outer edge portion of the heating plate 50. The upper frame-shaped portion 251 is provided at both ends of the upper edge portion 50a in the left-right direction X1. The upper frame-shaped portion 251 is formed into a square shape, and a hole 290 is formed in the center of the upper frame-shaped portion 251 to engage with the upper hook portion 170 of the frame-shaped frame body 51. The hole 290 has a width that is the same as the width of the upper hook portion 170 in the left-right direction X1.

[0070] The lower frame-like portion 252 is provided, for example, at the lower edge portion 50b, which is the second outer edge portion of the heating plate 50. The lower frame-like portion 252 is located at the center of the lower edge portion 50b in the left-right direction X1. The lower frame-like portion 252 is formed into a square shape, and a hole 291 is formed in the center of the lower frame-like portion 252 to engage with the protrusion 180 of the frame-like body 51. The hole 291 has a width that is the same as the width of the lower hook portion 190 in the left-right direction X1.

[0071] The vertical distance L1 from the hole 290 in the upper frame portion 251 of the heating plate 50 to the hole 291 in the lower frame portion 252 in the vertical direction X2 is set to be the same as the vertical distance L2 from the upper hook portion 170 to the protrusion 180 of the frame body 51 in the vertical direction X2 (shown in...). Figure 5 They are roughly the same length.

[0072] like Figure 10As shown, the pressing member 52 has a generally rectangular, thin plate shape. The pressing member 52 is transparent, for example, made of PET (polyethylene terephthalate). The low-temperature flexibility and impact strength of the pressing member 52 are higher than those of the heating plate 50 at low temperatures. The area of ​​the pressing member 52 is larger than that of the heating plate 50, and it can cover the entire surface of the heating plate 50.

[0073] The pressing member 52 has two upper protrusions 300 at its two ends in the left-right direction X1 at the top and protruding upward. The pressing member 52 has a connecting portion 301 that extends along the left-right direction X1 at the top and connects the upper protrusions 300 to each other.

[0074] The pressing member 52 has two lower protrusions 310 at its two ends in the left-right direction X1 at the bottom. In addition, the pressing member 52 has a recess 311 in the center of the lower left-right direction X1.

[0075] The pressing member 52 includes: an upper locking part 320 for locking the hook part 170 of the upper part 51a of the frame-shaped frame 51; a lower locking part 321 for locking the hook part 190 of the lower part 51b of the frame-shaped frame 51; and a pressing part 322, which is connected to the heating plate 50 of the pressing tube 54 of the frame-shaped frame 51.

[0076] The upper locking part 320 is formed by a square-shaped opening. The upper locking part 320 is provided on the upper protrusion 300.

[0077] The lower locking part 321 is formed by a square-shaped opening. The lower locking part 321 is provided on the lower protrusion 310.

[0078] The holding part 322 is composed of the connecting part 301. The holding part 322 can hold the connecting area 54a of the tube 54 connected to the heating flow path 262 towards the upper part 51a of the frame-shaped body 51.

[0079] The vertical distance L3 from the upper locking part 320 to the lower locking part 321 of the pressing member 52 in the vertical direction X2 is set to be the same as the vertical distance L4 from the upper hook part 170 to the lower hook part 190 of the frame 51 in the vertical direction X2 (shown in...). Figure 5 The length is approximately the same. Additionally, the distance L5 in the vertical direction X2 from the top of the upper hook 170 to the upper limiting part 200 (shown in...) Figure 6 The distance L6 is less than the vertical distance X2 from the upper end of the upper protrusion 300 of the pressing member 52 to the upper locking part 320 (opening) (shown in...). Figure 10 Preferably, it should be 3mm or smaller. Similarly, the distance L7 from the top of the lower hook portion 190 to the lower limiting portion 210 in the vertical direction X2 (shown in...) Figure 8The distance L8 is less than the vertical distance X2 from the lower end of the lower protrusion 310 of the pressing member 52 to the lower locking part 321 (opening) (shown in...). Figure 10 (Preferably, the size should be 3mm or larger.)

[0080] <Mechanism for engaging the heating plate and the frame>

[0081] like Figure 4 As shown, the flow path holding device 40 has a first engaging mechanism 350 and a second engaging mechanism 351 that engage the heating plate 50 and the frame-shaped body 51.

[0082] The first engaging mechanism 350 engages the upper part of the heating plate 50 with the frame-shaped body 51. The first engaging mechanism 350 is, for example, composed of the upper frame-shaped part 251 of the heating plate 50 and the upper hook part 170 of the frame-shaped body 51.

[0083] The second engaging mechanism 351 engages the lower part of the heating plate 50 with the frame-shaped body 51. The second engaging mechanism 351 is, for example, composed of the lower frame-shaped part 252 of the heating plate 50 and the protrusion 180 of the frame-shaped body 51.

[0084] When the heating plate 50 and the frame-like body 51 are engaged using the first engaging mechanism 350 and the second engaging mechanism 351, the two upper frame-like portions 251 of the heating plate 50 are locked to the upper hook portions 170 of the frame-like body 51, and one lower frame-like portion 252 is embedded in the protrusion 180 of the frame-like body 51. As a result, at the first engaging mechanism 350, the heating plate 50 and the frame-like body 51 are engaged so that the heating plate 50 will not move relative to the frame-like body 51 in the surface direction X of the heating plate 50 and in the vertical direction Z perpendicular to the surface direction X. At the second engaging mechanism 351, the heating plate 50 and the frame-like body 51 are engaged so that the heating plate 50 will not move relative to the frame-like body 51 in the surface direction X of the heating plate 50, but can move in the vertical direction Z.

[0085] <Clocking mechanism for pressing components>

[0086] like Figure 3 As shown, the flow path holding device 40 includes a locking mechanism 360 for locking the pressing member 52 into the frame-shaped frame 51.

[0087] The locking mechanism 360 is, for example, composed of an upper locking part 320 and a lower locking part 321 of the pressing member 52, and an upper hook part 170 and a lower hook part 190 of the frame-shaped body 51.

[0088] When the locking mechanism 360 locks the pressing member 52 and the frame-shaped frame 51 together, the two upper locking parts 320 of the pressing member 52 are locked to the upper hook parts 170 of the frame-shaped frame 51, and the two lower locking parts 321 are locked to the lower hook parts 190 of the frame-shaped frame 51.

[0089] <Metrological Chamber>

[0090] like Figure 1 and Figure 2 As shown, the metering chamber 53 is located at the lower part of the frame-like body 51. The metering chamber 53 is a chamber used to manage the amount of fluid removed from the patient and to meter the total amount of dialysate supplied to the blood purifier 70, the amount of waste dialysate discarded from the blood purifier 70, and the amount of rehydration fluid supplied to the blood circuit 71. Figure 11 As shown, the metering chamber 53 is formed in the shape of a plate and is made of thermoplastic resin. The metering chamber 53 has three storage sections 400, 401, and 402; seven inlets and outlets 410 to 416; and seven flow paths 420 to 426.

[0091] Storage units 400, 401, and 402 are arranged laterally in the lower part of the metering chamber 53 in this order. For example, the first inlet / outlet 410 to the fourth inlet / outlet 413 are arranged from bottom to top on the upper left side of the metering chamber 53 in this order, and the fifth inlet / outlet 414 to the seventh inlet / outlet 416 are arranged from bottom to top on the upper right side of the metering chamber 53 in this order. The first flow path 420 connects the first storage unit 400 and the first inlet / outlet 410, the second flow path 421 connects the first storage unit 400 and the second inlet / outlet 411, the third flow path 422 connects the second storage unit 401 and the third inlet / outlet 412, and the fourth flow path 423 connects the second storage unit 401 and the fourth inlet / outlet 413. The fifth flow path 424 connects the second storage section 401 and the fifth inlet / outlet 414. The sixth flow path 425 connects the third storage section 402 and the sixth inlet / outlet 415. The seventh flow path 426 connects the third storage section 402 and the seventh inlet / outlet 416.

[0092] The first inlet / outlet 410 and the second inlet / outlet 411 are connected to the pipe 54 of the waste fluid flow path 130 of the flow path holding device 40. Thus, the first storage unit 400 functions as a metering unit to temporarily store and measure the dialysate discarded from the blood purifier 70. The third inlet / outlet 412 and the fifth inlet / outlet 414 are connected to the pipe 54 of the dialysate flow path 121 of the flow path holding device 40. Thus, the second storage unit 401 functions as a metering unit to temporarily store and measure the dialysate supplied to the blood purifier 70. The sixth inlet / outlet 415 is connected to the pipe 54 of the replenishment flow path 141 of the flow path holding device 40. Thus, the third storage unit 402 functions as a metering unit to temporarily store and measure the replenishment fluid supplied to the blood circuit 71.

[0093] The metering chamber 53 uses the metering device 32 in the main body 10 to measure the total weight of the amount of dialysis fluid supplied to the blood purifier 70, the amount of waste dialysis fluid discarded from the blood purifier 70, and the amount of replenishment fluid supplied to the blood circuit 71. The metering chamber 53 can grasp the change in the total weight, i.e. the change in the amount of fluid removed from the patient.

[0094] Figure 2 The tube 54 shown is made of soft vinyl chloride. The tube 54 mainly constitutes part or all of the dialysate flow path 121, part or all of the waste liquid flow path 130, and part or all of the replenishment flow path 141. At least a portion of the tube 54 is fixed to the fixing part 161 of the frame-shaped body 51.

[0095] Next, the method of using the flow path holding device 40 configured as described above will be explained.

[0096] like Figure 4 As shown, a heating plate 50 is mounted on a frame-like body 51. At this time, at the first engaging mechanism 350 and the second engaging mechanism 351, the two upper frame-like portions 251 of the heating plate 50 are engaged with the upper hook portions 170 of the frame-like body 51, and one lower frame-like portion 252 is embedded in the protrusion 180 of the frame-like body 51. As a result, at the first engaging mechanism 350, the heating plate 50 and the frame-like body 51 are engaged so that the heating plate 50 will not move relative to the frame-like body 51 in the surface direction X and the vertical direction Z. At the second engaging mechanism 351, the heating plate 50 and the frame-like body 51 are engaged so that the heating plate 50 will not move relative to the frame-like body 51 in the surface direction X, but can move in the vertical direction Z.

[0097] Next, as Figure 3 As shown, a pressing member 52 for pressing the heating plate 50 is installed on the frame-like body 51. The pressing member 52 is located on the surface side of the heating plate 50 in the vertical direction Z. Figure 3 (The paper surface near the front side) presses the heating plate 50 from the Z-side surface in the vertical direction. At this time, at the locking mechanism 360, the two upper locking parts 320 of the pressing member 52 are locked to the upper hook part 170 of the frame-shaped frame 51, and the two lower locking parts 321 are locked to the lower hook part 190 of the frame-shaped frame 51.

[0098] Then, the flow path holding device 40 is installed on the assembly part 33 of the main body 10 with the heating plate 50, pressing member 52 and tube 54 installed on the frame 51.

[0099] According to this embodiment, the flow path holding device 40 includes: a first engaging mechanism 350 that engages the heating plate 50 and the frame 51 in a manner that restricts the movement of the heating plate 50 relative to the frame 51 along the surface direction X and the vertical direction Z of the heating plate 50 during engagement; and a second engaging mechanism 351 that, at a different position from the first engaging mechanism 350, engages the heating plate 50 and the frame 51 in a manner that restricts the movement of the heating plate 50 relative to the frame 51 along the surface direction X of the heating plate 50 during engagement while allowing the heating plate 50 to move along the vertical direction Z. Thus, through the second engaging mechanism 351, a portion of the heating plate 50 can move relative to the frame 51 along the vertical direction Z, thereby, for example, suppressing the possibility of the heating plate 50 also bending and breaking when the frame 51 flexes. Furthermore, since the heating plate 50 is positioned by the first engaging mechanism 350 and the second engaging mechanism 351, the heating plate 50 can be appropriately heated by the heater 31 of the blood purification device 1. Also, since the flow path holding device 40 has a pressing member 52 for pressing the heating plate 50, even if a portion of the heating plate 50 is moved relative to the frame 51 in the vertical direction Z by the second engaging mechanism 351, the heating plate 50 can be prevented from detaching from the frame 51.

[0100] The second engaging mechanism 351 consists of a protrusion 180 and a lower frame-like portion 252. The protrusion 180 is formed on the frame-like body 51 and extends in the vertical direction Z. The lower frame-like portion 252 is formed on the heating plate 50, and a hole 291 is formed in the lower frame-like portion 252 for the protrusion 180 to pass through. As a result, the heating plate 50 cannot move properly relative to the frame-like body 51 in the surface direction X, but can move properly relative to the frame-like body 51 in the vertical direction Z.

[0101] The first engaging mechanism 350 consists of an upper hook portion 170 and an upper frame-shaped portion 251. The upper hook portion 170 is formed on the frame-shaped body 51, and the upper frame-shaped portion 251 is formed on the heating plate 50. A hole 290 is formed in the upper frame-shaped portion 251 for engaging with the upper hook portion 170. This prevents the heating plate 50 from moving appropriately relative to the frame-shaped body 51 in the surface direction X and the vertical direction Z.

[0102] The first engaging mechanism 350 is provided on the upper edge 50a of the heating plate 50, and the second engaging mechanism 351 is provided on the lower edge 50b of the heating plate 50. Thus, the first engaging mechanism 350 and the second engaging mechanism 351 are arranged separately, which can sufficiently ensure the amount of movement of the heating plate 50 in the vertical direction Z.

[0103] The second engaging mechanism 351 is located at the center of the lower edge 50b of the heating plate 50 in the left-right direction (edge ​​direction) X1. As a result, the heating plate 50 can move without left-right deviation in the vertical direction Z, which more effectively suppresses damage to the heating plate 50.

[0104] The first engaging mechanism 350 is provided at least at both ends of the upper edge 50a of the heating plate 50 in the left-right direction X1. As a result, the movement of the heating plate 50 can be sufficiently restricted without left-right deviation.

[0105] Because the pressing member 52 has a plate-like shape that covers the heating plate 50, it can properly press the entire heating plate 50 without causing localized stress concentration. Furthermore, the pressing member 52 can protect the heating plate 50 from contact with external objects during transport and other situations.

[0106] The pressing member 52 presses the heating plate 50 relative to the frame-like body 51 so that the engagement between the heating plate 50 and the frame-like body 51 based on the first engagement mechanism 350 and the second engagement mechanism 351 will not disengage. Thus, it is possible to effectively prevent the heating plate 50 from disengaging from the frame-like body 51.

[0107] Since the pressing member 52 is locked to the frame-like body 51, the deflection of the frame-like body 51 can be reduced by using the pressing member 52. In addition, the pressing member 52 can be easily installed in the specified position.

[0108] The frame-like body 51 has an upper hook portion 170 and a lower hook portion 190 that engage the pressing member 52; and an upper limiting portion 200 and a lower limiting portion 210 that prevent the pressing member 52 from disengaging from the upper hook portion 170 and the lower hook portion 190. Therefore, in cases such as when the frame-like body 51 flexes, the upper and lower ends of the pressing member 52 abut against the upper limiting portion 200 and the lower limiting portion 210, restricting the movement of the pressing member 52. Thus, it is possible to prevent the pressing member 52 from disengaging from the hook portions 170 and 190.

[0109] The tube 54 has a connection region 54a that connects to the heating flow path 262 of the heating plate 50. The connection region 54a is disposed on the frame-like body 51. The pressing member 52 has a pressing part 322 that presses the connection region 54a of the tube 54 against the frame-like body 51. Depending on the arrangement direction of the tube 54 connected to the heating flow path 262, an external force may be applied that causes the connection region 54a to bulge in the vertical direction Z. However, since the connection region 54a is pressed by the pressing part 322, the bulging of the connection region 54a can be suppressed. Thus, for example, when the heating plate 50 is pressed against the heater 31 using the door 30 of the device body 10, damage or deformation of the heating plate 50 can be prevented.

[0110] The heating plate 50 is made of vinyl chloride. In this case, the connection between the heating plate 50 and the vinyl chloride pipe 54 can be easily made. On the other hand, although the strength of the heating plate 50 will decrease at low temperatures, damage to the heating plate 50 can be suppressed by allowing the heating plate 50 to move in the vertical direction Z.

[0111] The structure of the flow path holding device 40 described in the above embodiments is not limited to this. For example, the frame-shaped body 51 may have other structures. For example, the shape, arrangement, and number of the upper hook portion 170, protrusion 180, lower hook portion 190, upper limiting portion 200, and lower limiting portion 210 of the frame-shaped body 51 are also not limited to this. For example, as Figure 12 As shown, in other forms of the frame 51, one of the lower limiting portions 210 of the frame 51 is divided into two, arranged separately to the left and right relative to the lower hook portion 190. Alternatively, the other lower limiting portion 210 may be located at a position offset to the outside of the lower hook portion 190 in the left-right direction X1.

[0112] The structure of the heating plate 50 is not limited to the above-described embodiment. The number, arrangement, and shape of the engaging portions of the first engaging mechanism 350 and the second engaging mechanism 351 are not limited to the above-described embodiment. For example, the protrusion 180 and the lower frame-like portion 252 of the second engaging mechanism 351 may be provided in multiple locations. In addition, the number of engaging mechanisms of the heating plate 50 is not limited to the first engaging mechanism 350 and the second engaging mechanism 351, but may be three or more. Alternatively, the protrusion 180 and the frame-like portion 252 of the second engaging mechanism 351 may be provided in the upper part of the frame-like frame 51, and the hook portion 170 and the frame-like portion 251 may be provided in the lower part of the frame-like frame 51. Furthermore, in this invention, "restricting the movement of the heating plate relative to the frame body along the surface direction and vertical direction of the heating plate during engagement" and "restricting the movement of the heating plate relative to the frame body along the surface direction of the heating plate during engagement" means that, during engagement based on the first engagement mechanism and the second engagement mechanism, the heating plate can move slightly as long as it is not moved relative to the frame body to a substantially positioned position.

[0113] The structure of the pressing member 52 is not limited to the above-described embodiments. The number, arrangement, shape, etc. of the locking parts of the locking mechanism 360 are not limited to the above-described embodiments.

[0114] The structure of the metering chamber 53 and the tube 54 is not limited to the above-described embodiments. Furthermore, the flow path holding device 40 may not include a metering chamber.

[0115] The structure of the blood purification device 1 with the flow path holding device 40 is not limited to the above embodiments. For example, the blood purification device 1 in the above embodiments is used for dialysis treatment, but the present invention can also be applied to other liquid treatment devices such as plasma exchange therapy, leukocyte removal therapy, and continuous slow blood filtration therapy.

[0116] Industrial availability

[0117] This invention is useful in preventing the heating plate that engages with the frame in a flow path holding device from breaking or detaching.

Claims

1. A flow path holding device that holds a liquid flow path, wherein, The flow path holding device includes: A heating plate having a heating flow path for heating a liquid flowing in the heating flow path; A frame-shaped body having an opening on the inside, the frame-shaped body engaging with the heating plate in such a way that the heating plate is positioned in the opening; The pressing member presses down on the heating plate to prevent it from detaching from the frame-like body; The first engaging mechanism engages the heating plate and the frame-like frame in such a way that it restricts the movement of the heating plate relative to the frame-like body along the surface direction of the heating plate and in a vertical direction perpendicular to that surface direction during engagement; and The second engaging mechanism, located at a different position than the first engaging mechanism, engages the heating plate and the frame body in such a manner that, during engagement, it restricts the movement of the heating plate relative to the frame-like body along the surface direction of the heating plate while allowing the heating plate to move along the vertical direction. The flow path holding device is configured such that a portion of the heating plate can move relative to the frame-shaped body in the vertical direction via the second engagement mechanism.

2. The flow path holding device according to claim 1, wherein, The second engaging mechanism consists of a protrusion and a frame-shaped portion. The protrusion is formed on the frame-shaped body and extends along the vertical direction. The frame-shaped portion is formed on the heating plate and has a hole through which the protrusion passes.

3. The flow path holding device according to claim 1 or 2, wherein, The first engaging mechanism consists of a hook and a frame. The hook is formed on the frame and the frame is formed on the heating plate. A hole is formed in the frame to engage with the hook.

4. The flow path holding device according to claim 1 or 2, wherein, The first engaging mechanism is located on the first outer edge of the heating plate, and the second engaging mechanism is located on the second outer edge of the heating plate opposite to the first outer edge.

5. The flow path holding device according to claim 4, wherein, The second engaging mechanism is located at the center of the second outer edge of the heating plate in the edge direction.

6. The flow path holding device according to claim 4, wherein, The first engaging mechanism is provided at least at both ends of the first outer edge of the heating plate in the edge direction.

7. The flow path holding device according to claim 1, wherein, The pressing member has a plate-like shape that covers the heating plate.

8. The flow path holding device according to claim 1, wherein, The pressing member presses the heating plate relative to the frame-shaped body so that the engagement between the heating plate and the frame-shaped body based on the first engagement mechanism and the second engagement mechanism will not disengage.

9. The flow path holding device according to claim 1, wherein, The pressing component is locked into the frame-shaped frame.

10. The flow path holding device according to claim 9, wherein, The frame-like body has a limiting portion that prevents the pressing member, which is locked to the frame-like body, from disengaging from the frame-like body.

11. The flow path holding device according to claim 9 or 10, wherein, The flow path holding device includes a locking mechanism for locking the pressing member into the frame-shaped frame. The locking mechanism includes a hook portion provided in the frame-shaped body and an opening provided in the pressing member.

12. The flow path holding device according to claim 1, wherein, The liquid flow path has a pipe with a connection area that connects to the heating flow path of the heating plate. The connecting area is disposed on the frame-shaped frame. The pressing member has a pressing portion that presses against the connecting area of ​​the tube relative to the frame-shaped body.

13. The flow path holding device according to claim 1, wherein, The heating plate is made of vinyl chloride.

14. A liquid handling apparatus, wherein, The liquid handling apparatus comprises a flow path holding device as described in any one of claims 1 to 13 and a device body for free mounting of the flow path holding device.

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