Gas detection fixture

Abstract

One aspect of an embodiment of the present application relates to a gas detection fixture (40), which includes: a base (42); a first clamping portion (44) disposed on the base (42); and a second clamping portion (46) disposed on the base (42), wherein a clamping space (48) is defined between the second clamping portion (46) and the first clamping portion (44), and the second clamping portion (46) includes an outer surface (50) away from the first clamping portion (44) and a through portion (52) penetrating the outer surface (50) and the clamping space (48).

Description

Technical Field

[0001] The invention relates to the pharmaceutical field, and in particular to a gas detection fixture. Background Art

[0002] Disposable pharmaceutical systems with specific functions are often used in pharmaceutical processes. Disposable pharmaceutical systems are generally composed of disposable components such as membranes, hoses, connectors, stirring paddles, filters, sensors, etc. During the manufacturing process and / or before and after use by users, the integrity of disposable pharmaceutical systems is usually tested to determine whether they have leakage defects.

[0003] However, existing inspection fixtures are not ideal. Summary of the invention

[0004] An object of the present invention is to provide an improved gas detection fixture.

[0005] In view of the above purpose, one aspect of an embodiment of the present invention relates to a gas detection clamp, which includes: a base; a first clamping part, which is arranged on the base; and a second clamping part, which is arranged on the base, and a clamping space is defined between the second clamping part and the first clamping part, and the second clamping part includes an outer surface away from the first clamping part and a through part that passes through the outer surface and the clamping space.

[0006] In some embodiments, there are a plurality of second clamping portions, and at least one of the second clamping portions can move away from another second clamping portion adjacent thereto to define a through portion therebetween.

[0007] In some embodiments, the gas detection fixture includes a first slide rail disposed on the base, and at least one of the second clamping parts can move along the first slide rail.

[0008] In some embodiments, the base includes a receiving groove that receives the first slide rail.

[0009] In some embodiments, the gas detection fixture includes a second slide rail disposed on the base and connected to the first clamping portion.

[0010] In some embodiments, the base includes a receiving groove that receives the second slide rail.

[0011] In some embodiments, the distance between the first clamping portion and the opposite second clamping portion is smaller than the minimum external dimension corresponding to the nominal volume of the detected object.

[0012] In some embodiments, the distance between the first clamping portion and the opposite second clamping portion is in the range of 0.5 cm to 5 cm.

[0013] In some embodiments, the gas detection fixture includes a holding portion, which can hold the relative positions of the first holding portion and the second holding portion.

[0014] In some embodiments, the retaining portion includes a locking member that cooperates with the first clamping portion and the second clamping portion.

[0015] In some embodiments, the retaining portion includes a first groove and a second groove respectively provided on the first clamping portion and the second clamping portion and cooperating with the locking member.

[0016] In some embodiments, the first clamping portion includes an opposite surface opposite to the outer surface, and the locking member includes a first locking portion and a second locking portion protruding from the opposite surface and the outer surface, respectively.

[0017] In some embodiments, there are multiple second clamping parts, at least one of the second clamping parts and another second clamping part adjacent thereto respectively include a first edge through hole and a second edge through hole, and the second edge through hole is opposite to and communicates with the first edge through hole to define a through portion.

[0018] In some embodiments, the gas detection clamp includes a base, which includes a bottom wall, a first side wall extending from the bottom wall and close to the first clamping portion, a second side wall extending from the bottom wall and close to the second clamping portion, a first end wall connecting the first side wall and the second side wall, and a splicing end, which can be spliced ​​with another gas detection clamp.

[0019] In some embodiments, the base includes a base slide rail, which includes a butt end surface exposed outside the splicing end, and the first clamping portion and the second clamping portion can move along the base slide rail.

[0020] In some embodiments, the gas detection fixture includes a base, which includes a bottom wall, a first side wall extending from the bottom wall and close to the first clamping portion, a second side wall extending from the bottom wall and close to the second clamping portion, a first end wall connecting the first side wall and the second side wall, and a second end wall connecting the first side wall and the second side wall, which together with the first end wall, the first side wall and the second side wall partially surround the first clamping portion and the second clamping portion.

[0021] In some embodiments, the base includes a base slide rail, and the first clamping portion and the second clamping portion can reciprocate between the first end wall and the second end wall along the base slide rail.

[0022] In some embodiments, the gas detection fixture includes a base and a moving part, the base supports the first clamping part and the second clamping part, and the base can move with the movement of the moving part.

[0023] In some embodiments, there are a plurality of second clamping portions, and at least one of the second clamping portions can move relative to another second clamping portion adjacent thereto to move away from or closer to each other.

[0024] In some embodiments, there are a plurality of first clamping portions, and at least one of the first clamping portions can move relative to another first clamping portion adjacent thereto to move away from or closer to each other.

[0025] If technical conditions permit, the technical solutions of the embodiments of the present application can be combined arbitrarily.

[0026] The present application will be further described below in conjunction with the accompanying drawings. The same or similar reference numerals may be used in the drawings to refer to the same or similar elements, devices, shapes, structures, and steps in different embodiments, and the descriptions of the same or similar elements, devices, shapes, structures, steps, features, and effects in different embodiments and the descriptions of the prior art elements, devices, shapes, structures, steps, features, and effects may be omitted. BRIEF DESCRIPTION OF THE DRAWINGS

[0027] Figure 1 is a schematic structural diagram of a gas detection device according to some embodiments of the present invention;

[0028] Figure 2 is a schematic diagram of the structure of a gas path control component of a gas detection device according to some embodiments of the present invention;

[0029] Figure 3 for Figure 1 A schematic diagram of the valve status combination of the gas circuit control components of the gas detection equipment;

[0030] Figure 4 is a three-dimensional schematic diagram of a gas detection fixture according to some embodiments of the present invention;

[0031] Figure 5 for Figure 4 A schematic side view of the gas detection fixture;

[0032] Figure 6 yes Figure 4 A schematic diagram of the rear view of the gas detection fixture;

[0033] Figure 7 for Figure 4 A three-dimensional schematic diagram of a gas detection fixture holding an object to be detected;

[0034] Figure 8 yes Figure 7 Schematic diagram of two states of the detected object;

[0035] Fig. 9 A schematic diagram of a partial explosion of a gas detection fixture according to some embodiments of the present invention;

[0036] Fig.10 yes Fig. 9 A three-dimensional schematic diagram of the gas detection fixture in the assembled state;

[0037] Fig.11 is a three-dimensional schematic diagram of a gas detection fixture according to some embodiments of the present invention;

[0038] Fig.12 yes Fig.11 A partial enlarged schematic diagram of a gas detection fixture;

[0039] Fig.13 is a three-dimensional schematic diagram of a gas detection fixture according to some embodiments of the present invention;

[0040] Fig.14 is a flow chart of a gas detection method according to some embodiments of the present invention; and

[0041] Fig.15 Schematic diagram of the structure of gas detection equipment according to some embodiments of the present invention. DETAILED DESCRIPTION

[0042] Figure 1 Schematic diagram of the structure of a gas detection device according to some embodiments of the present invention. Figure 1 As shown, one aspect of an embodiment of the present invention relates to a gas detection device 10, which includes: a gas input passage 12; a first pressure regulating valve 14, which is in gas communication with the gas input passage 12; a first pressure sensor 16, which is in gas communication with the gas input passage 12 and the first pressure regulating valve 14; a first gas delivery passage 18, which can be in gas communication with the gas input passage 12 to deliver gas at a first flow rate; a second gas delivery passage 20, which can be in gas communication with the gas input passage 12 to deliver gas at a second flow rate, the second flow rate being less than the first flow rate; a gas output interface 22, which can be in gas communication with the first gas delivery passage 18 and the second gas delivery passage 20; a second pressure sensor 24, which is in gas communication with the gas output interface 22; and a gas circuit control component 26, which is configured to be used to regulate the gas delivery state of the gas output interface 22.

[0043] The terms "first", "second", and similar terms in this application are not intended to indicate priority, importance, time sequence, etc., but are mainly used to distinguish the elements, devices, shapes, structures, etc. that they modify.

[0044] The gas detection device 10 according to the embodiment of the present invention may be connected to an external gas source (not shown) through a gas input passage 12 to input gas, or may be provided with a gas source (not shown) connected to the gas input passage 12. The gas source may collect, prepare, and store gas.

[0045] The gas detection device 10 can communicate with the detected object 60 ( Figure 7 ) connection, during the process of the manufacturer manufacturing the detected object 60, and / or before and after the user uses the detected object 60, the integrity of the detected object 60 is detected by means of gas detection, and the applicability is wide.

[0046] The detected object 60 may be a disposable pharmaceutical system, which may be composed of disposable components such as a film, a hose, a connector, a stirring paddle, a filter, a sensor, etc., and may have specific functions used in pharmaceutical processes, such as storing and preparing liquids.

[0047] When the gas detection device 10 is working, the gas can flow through the gas input passage 12, the first gas delivery passage 18, the gas circuit control component 26, the gas output interface 22, and the detected object 60 at a first flow rate, and / or flow through the gas input passage 12, the second gas delivery passage 20, the gas circuit control component 26, the gas output interface 22, and the detected object 60 at a second flow rate.

[0048] The second flow rate is smaller than the first flow rate, which can help to quickly inflate the detected object 60 with the large first flow rate and save inflation time, and to accurately inflate the detected object 60 and adjust the air pressure with the small second flow rate. The combination of large and small flow rates can help the gas detection equipment 10 to perform integrity detection of the detected object 60 in a shorter time and with higher efficiency.

[0049] The first pressure sensor 16 may be an electrical component for detecting pressure changes. The first pressure sensor 16 may detect changes in the gas pressure of the gas input passage 12. By selecting different electrical models, the pressure range measured by the first pressure sensor 16 may be from -1000 mbar to 10000 mbar, or from 0 mbar to 1000 mbar.

[0050] The first pressure regulating valve 14 can regulate the output gas pressure of the gas input passage 12. In some embodiments, the first pressure regulating valve 14 is a high-precision micro-pressure regulating valve.

[0051] The high-precision micro-pressure regulating valve 14 can adjust the output gas pressure of the gas input passage 12, and after reaching the set pressure, it can maintain a stable gas output at the pressure. If the downstream pressure of the gas input passage 12 is higher than the output pressure of the high-precision micro-pressure regulating valve 14, the high-precision micro-pressure regulating valve 14 can release the pressure to achieve the effect of maintaining a stable pressure.

[0052] In some embodiments, the gas detection device 10 includes a second pressure regulating valve 28 in gas communication with the first gas delivery passage 18 .

[0053] The second pressure regulating valve 28 can adjust the on-off state of the first gas delivery passage 18 and the size of the first flow rate.

[0054] In some embodiments, the second pressure regulating valve 28 is a micro-pressure and large-flow pressure regulating valve.

[0055] The micro-pressure and high-flow pressure regulating valve 28 can be a specially configured valve that can output gas at a high flow rate at very low pressure. According to the valve structure and the flow limiting setting, the pressure range of the micro-pressure and high-flow pressure regulating valve 28 can be within 200 mbar, and the flow rate can reach 1 liter to 100 liters per minute.

[0056] In some embodiments, the gas detection device 10 includes multiple gas output interfaces 22, multiple second pressure sensors 24, and multiple gas circuit control components 26, and the first gas delivery passage 18 includes multiple first branches 30 connected in parallel to each other, each first branch 30 can be gas-connected to the gas input passage 12, and each first branch 30 can correspond to a gas output interface 22, a second pressure sensor 24, and a gas circuit control component 26.

[0057] Each gas output interface 22 may correspond to a detected object 60. The gas detection device 10 may rapidly inflate and detect multiple detected objects 60 in parallel. For example, Figure 1 The gas output from the gas input passage 12 of the gas detection device 10 can pass through at most four first branches 30 in parallel to quickly inflate four detected objects 60.

[0058] In some embodiments, the second gas delivery passage 20 includes multiple second branches 32 connected in parallel, each second branch 32 can be gas-connected to the gas input passage 12, and each second branch 32 can correspond to a gas output interface 22, a second pressure sensor 24, and a gas circuit control component 26.

[0059] The gas detection device 10 can inflate and detect multiple detected objects 60 in parallel with a small flow rate. For example, Figure 1 The gas output from the gas input passage 12 of the gas detection device 10 can pass through up to four second branches 32 in parallel to inflate four detected objects 60 with a small flow rate.

[0060] In some embodiments, the gas detection device 10 includes a plurality of third pressure regulating valves 34 , each of which is in gas communication with a second branch 32 .

[0061] The third pressure regulating valve 34 can adjust the gas on / off and flow rate of the corresponding second branch 32 .

[0062] In some embodiments, the third pressure regulating valve 34 is a precision pressure regulating valve.

[0063] The precision pressure regulating valve 34 can be an electrical component, and can adjust the gas pressure outputted by the precision pressure regulating valve 34 within a set range according to the instructions given by the gas detection device 10. The precision pressure regulating valve 34 can adjust the output pressure range according to the electrical model, for example, 0-10000 mbar, or 0-1000 mbar. In this way, it can be beneficial to precisely adjust the gas pressure of the second branch 32, the gas output interface 22, and the detected object 60.

[0064] The second pressure sensor 24 may be an electrical component for detecting pressure changes. The second pressure sensor 24 may detect changes in the gas pressure of the gas output interface 22 and the object 60 connected to the gas output interface 22, so as to help detect whether the object 60 is intact and has no leakage defects. In some embodiments, the second pressure sensor 24 is a high-precision pressure sensor.

[0065] The second pressure sensor 24 can be "micro-pressure high-precision". By selecting different electrical models, the pressure range measured by the second pressure sensor 24 can be from 0 mbar to 1000 mbar, or from -1000 mbar to 10000 mbar. The high-precision measurement accuracy of the second pressure sensor 24 can reach 0.1% or higher. In this way, it can be beneficial for the gas detection device 10 to have high detection degree and sensitivity.

[0066] Figure 2 Schematic diagram of the structure of the gas circuit control component of the gas detection device according to some embodiments of the present invention. Figure 1 and 2 In some embodiments, the gas circuit control component 26 includes a three-way valve 36 and a one-way valve 38 .

[0067] In this way, it is advantageous to adjust the gas delivery state of the gas output interface 22 by changing the valve states of the three-way valve 36 , the one-way valve 38 , etc.

[0068] The gas circuit control member 26 can be as follows Figure 1 The three-way valve 36 is shown. Figure 2 The one-way valve 38 is shown, or other valves are included in embodiments not shown, and / or any combination of three-way valves, one-way valves, and other valves.

[0069] In some embodiments, the gas output interface 22 has multiple gas delivery states.

[0070] The various gas delivery states of the gas output interface 22 may correspond to the various gas path states of the gas detection device 10 .

[0071] In some embodiments, the gas delivery state of the gas output interface 22 includes one or more of: reset, low-pressure and high-flow gas intake, low-pressure and high-precision gas intake, integrity detection, and exhaust.

[0072] In this way, different gas path requirements of the gas detection device 10 can be met.

[0073] For example, Figure 3 for Figure 1 Schematic diagram of valve status combination of gas circuit control components of gas detection equipment. In the example, one gas circuit control component 26 includes three three-way valves 36, and the valve status of each three-way valve 36 is represented by 0 and 1, 0 represents valve reset, and 1 represents valve set.

[0074] Figure 3 There are four logical combinations of the three-way valve 36 of the gas circuit control component 26, corresponding to the five logical states of the gas detection device 10, that is, the first to fifth states of the gas circuit control component 26 from left to right correspond to the five gas delivery states of the gas output interface 22, namely, reset, low-pressure and large-flow intake, low-pressure and high-precision intake, integrity detection, and exhaust. In these five gas delivery states of the gas output interface 22, the gas detection device 10 can be in the gas circuit states of reset, gas replenishment, pressure stabilization, detection, and exhaust, respectively.

[0075] When the gas detection device 10 is reset, it corresponds to the state 000 of the first gas circuit control component 26 on the left: the three three-way valves 36 are reset, and there is no gas circulation. When low-pressure and high-flow gas is inlet and replenished, it corresponds to the state 011 of the second gas circuit control component 26 on the left: the two three-way valves 36 are in place, and the first gas delivery passage 18 delivers gas. When low-pressure and high-precision gas is inlet, replenished, and pressure stabilized, it corresponds to the state 111 of the middle gas circuit control component 26: the three three-way valves 36 are in place, and the second gas delivery passage 20 delivers gas. During integrity testing, it corresponds to the state 000 of the fourth gas circuit control component 26 from the left: the three three-way valves 36 are reset, and the gas delivery to the object 60 to be detected is stopped. When the object 60 to be detected is exhausted, it corresponds to the state 001 of the first gas circuit control component 26 from the right: one three-way valve 36 is in place.

[0076] For example, when the nominal volume of the detected object 60 is small, the gas detection device 10 can be used directly with the detected object 60 to detect the integrity of the detected object 60. For example, when the nominal volume of the detected object 60 is large, the gas detection device 10 can also be used with a gas detection fixture to detect the integrity of the detected object 60.

[0077] The nominal volume may be a volume defined by the manufacturer for the capacity of the detected object 60. For example, a detected object 60 with a nominal volume of 10 liters should be able to contain a gas or liquid with a volume of 10 liters.

[0078] The detected object 60 can be a disposable two-dimensional liquid storage bag mainly composed of two plastic films, or a disposable three-dimensional liquid storage bag mainly composed of three or more plastic films. The nominal volume of the detected object 60 can be greater than or equal to 5 ml.

[0079] Figure 4 is a three-dimensional schematic diagram of a gas detection fixture according to some embodiments of the present invention. Figure 5 for Figure 4 Schematic side view of the gas detection fixture. Figure 6 yes Figure 4 Schematic diagram of the rear view of the gas detection fixture. Figures 4 to 6 As shown, another aspect of an embodiment of the present invention relates to a gas detection fixture 40, which includes: a base 42; a first clamping portion 44, which is disposed on the base 42; and a second clamping portion 46, which is disposed on the base 42, and a clamping space 48 is defined between the second clamping portion 46 and the first clamping portion 44, and the second clamping portion 46 includes an outer surface 50 away from the first clamping portion 44 and a through portion 52 that passes through the outer surface 50 and the clamping space 48.

[0080] The gas detection fixture 40 can be used for objects 60 of different sizes and structures. Figure 7 ). Specifically, a larger object 60 to be detected can be folded and placed in the clamping space 48, so that the possibility of being limited by the size of the clamping space 48 is relatively small. The combination of the clamping space 48 and the through-hole 52 can allow different structures of the object 60 to be detected, such as a film bag, a hose, a joint, a stirring paddle, a filter, a sensor, etc. Among them, the clamping space 48 can accommodate the film bag of the object 60 to be detected, while the part of the object 60 to be detected that cannot be accommodated by the clamping space 48, such as a hose, a joint, a stirring paddle, a filter, a sensor, etc., can protrude from the clamping space 48 from the through-hole 52.

[0081] The base 42 may be a long slot body with a substantially concave cross-section, closed at two long sides, and open at two short ends.

[0082] The first clamping portion 44 and the second clamping portion 46 may be substantially plate-shaped members and may stand parallel to each other in the base 42 along the thickness direction.

[0083] In some embodiments, there are a plurality of second clamping portions 46 , and at least one of the second clamping portions 46 can move away from another second clamping portion 46 adjacent thereto to define a through portion 52 therebetween.

[0084] In this way, the gas detection fixture 40 can have wide applicability.

[0085] For example, the through portion 52 can be defined by the specific position of the second clamping portion 46, and can be formed by the movement of at least one of the two adjacent second clamping portions 46. It can correspond to the protruding space required for matching any pipeline inlet and outlet, agitator base, feeding port and other components on the object to be detected 60 during the clamping process, so as to prevent the pipeline inlet and outlet, agitator base, feeding port and other components from being damaged due to excessive squeezing, thereby helping to achieve the clamping of any object to be detected 60.

[0086] Figure 7 for Figure 4 The three-dimensional schematic diagram of the gas detection fixture holding the object to be detected. Figure 7 As shown, in some embodiments, the gas detection fixture 40 includes a first slide rail 54 disposed on the base 42 , and at least one of the second clamping parts 46 can move along the first slide rail 54 .

[0087] In this way, the second clamping parts 46 can be conveniently moved, and at least one of any adjacent second clamping parts 46 can be moved to form the through parts 52 that meet the desired positions and sizes between each other.

[0088] In some embodiments, the base 42 includes a receiving groove 56 that receives the first slide rail 54 .

[0089] In this way, the first slide rail 54 can be installed firmly and the second clamping portion 46 can move smoothly.

[0090] The receiving groove 56 may be a groove with a substantially concave cross section. The depth of the receiving groove 56 may be less than the height of the second clamping portion 46, so as to provide a certain support to the lower portion of the second clamping portion 46 received therein without preventing the detected object 60 from partially protruding from the through portion 52 of the second clamping portion 46 not received therein.

[0091] In some embodiments, the gas detection fixture 40 includes a second slide rail 58 disposed on the base 42 and connected to the first clamping portion 44 .

[0092] In this way, the first clamping portion 44 can be advantageously movable relative to the base 42 .

[0093] The second slide rail 58 may have a similar configuration as the first slide rail 54 .

[0094] For example, when the size of the detected object 60 is small, the first clamping portion 44 can be moved to reduce the area of ​​the parallel alignment of the first clamping portion 44 and the second clamping portion 46, thereby reducing the size of the clamping space 48 therebetween. Conversely, when the size of the detected object 60 is large, the first clamping portion 44 can be moved to increase the area of ​​the parallel alignment of the first clamping portion 44 and the second clamping portion 46, thereby increasing the size of the clamping space 48 therebetween.

[0095] In some embodiments, the base 42 includes a receiving slot 56 that receives the second slide rail 58 .

[0096] In this way, the second slide rail 58 can be installed firmly and the first clamping portion 44 can move smoothly.

[0097] The receiving groove 56 may be a groove with a substantially concave cross section. The depth of the receiving groove 56 may be less than the height of the first clamping portion 44, thereby providing a certain support to the lower portion of the first clamping portion 44, reducing or avoiding the possibility of the first clamping portion 44 being separated from the base 42 and the second slide rail 58 after being squeezed by the detected object 60.

[0098] Figure 8 yes Figure 7 Schematic diagram of the two states of the detected object. Figure 5 , 7 and 8. In some embodiments, the distance D between the first clamping portion 44 and the opposite second clamping portion 46 is smaller than the minimum outer dimension S corresponding to the nominal volume of the detected object 60.

[0099] This can help limit the expansion volume of the object 60 being inspected and shorten the integrity inspection time of the object 60 being inspected.

[0100] The minimum external dimension S corresponding to the nominal volume of the detected object 60 may be the minimum value of the external dimension when it has the nominal volume, for example Figure 8 Here, the length S of the shortest side of the detected object 60 is when it is in a rectangular parallelepiped state with the left side fully stretched out.

[0101] For example, along Figure 8 After the object 60 is folded to a flat state, the dotted line on the right side of the image is used as shown in FIG. Figure 7 The method shown is used to insert the gas into the clamping space 48 to reduce the thickness, capacity and expansion volume of the object 60 to be tested, thereby reducing the amount of gas required for integrity testing and shortening the testing time.

[0102] In some embodiments, a distance D between the first clamping portion 44 and the opposite second clamping portion 46 is in a range of 0.5 cm to 5 cm.

[0103] In this way, it is beneficial to reduce the amount of gas required to be filled and shorten the detection time during the integrity detection of the detected object 60 between the first clamping portion 44 and the opposite second clamping portion 46 .

[0104] Fig. 9 FIG. 1 is a schematic diagram of a partial explosion of a gas detection fixture according to some embodiments of the present invention. Fig. 9 As shown, in some embodiments, the gas detection fixture 40 includes a holding portion 62 , which can hold the relative positions of the first holding portion 44 and the second holding portion 46 .

[0105] In this way, the gas detection fixture 40 can be clamped firmly and the relative positions of the first clamping portion 44 and the second clamping portion 46 can be prevented from changing in an undesirable manner.

[0106] In some embodiments, the retaining portion 62 includes a locking member 64 that cooperates with the first clamping portion 44 and the second clamping portion 46 .

[0107] In this way, it is helpful to simply realize that the retaining portion 62 retains the relative positions of the first clamping portion 44 and the second clamping portion 46 .

[0108] The locking member 64 may be, for example, a substantially rod-shaped member.

[0109] In some embodiments, the retaining portion 62 includes a first groove 66 and a second groove 68 respectively disposed on the first clamping portion 44 and the second clamping portion 46 and cooperating with the locking member 64 .

[0110] In this way, the locking member 64 can be facilitated to cooperate with the first clamping portion 44 and the second clamping portion 46 , and the retaining portion 62 can be facilitated to conveniently retain the relative positions of the first clamping portion 44 and the second clamping portion 46 .

[0111] The first groove 66 and the second groove 68 correspond to the shapes, sizes, and configurations of the portions of the locking member 64 that contact each other. For example, the first groove 66 and the second groove 68 may be substantially arc-shaped grooves.

[0112] Fig.10 yes Fig. 9 The three-dimensional schematic diagram of the gas detection fixture in the assembled state. Fig.10 In some embodiments, the first clamping portion 44 includes an opposite surface 70 opposite to the outer surface 50, and the locking member 64 includes a first locking portion 72 and a second locking portion 74 protruding from the opposite surface 70 and the outer surface 50 respectively.

[0113] In this way, the gas detection fixture 10 can be helpful in clamping and fastening the detected object 60 .

[0114] The first locking portion 72 and the second locking portion 74 may be roughly cylindrical in shape radially protruding along two opposite ends of the locking member 64 , and may respectively abut against the outer surface 50 and the opposite surface 70 to keep the spacing between the first clamping portion 44 and the second clamping portion 46 no greater than D.

[0115] Fig.11 Schematic diagram of a gas detection fixture according to some embodiments of the present invention. Fig.11As shown, in some embodiments, there are multiple second clamping portions 46, and at least one of the second clamping portions 46 and another second clamping portion 46 adjacent thereto respectively include a first edge through hole 75 and a second edge through hole 77, and the second edge through hole 77 is opposite to and communicates with the first edge through hole 75 to define a through portion 52.

[0116] In this way, it is possible to facilitate the components on the object 60 to be inspected to enter the through-portion 52 .

[0117] For example, the object 60 to be detected may be a disposable liquid storage bag (not shown) with a stirring paddle. When the disposable liquid storage bag is clamped in the clamping space 48 between the first clamping portion 44 and the second clamping portion 46, the stirring paddle (not shown) may protrude into the through portion 52 formed by the first edge hole 75 and the second edge hole 77 to avoid being squeezed and damaged.

[0118] In some embodiments, the gas detection clamp 40 includes a base 76, which includes a bottom wall 78, a first side wall 80 extending from the bottom wall 78 and close to the first clamping portion 44, a second side wall 82 extending from the bottom wall 78 and close to the second clamping portion 46, a first end wall 84 connecting the first side wall 80 and the second side wall 82, and a splicing end 86, which can be spliced ​​with another gas detection clamp 40.

[0119] In this way, it is helpful to adjust the length of the gas detection fixture 40 according to the size of the detected object 60. For example, two gas detection fixtures 40 can be spliced ​​and used together.

[0120] The base 76 may be a generally plate-shaped member.

[0121] The bottom wall 78 may be a generally plate-like member beneath the base 76 .

[0122] The first side wall 80 and the second side wall 82 may be generally plate-shaped members standing vertically from the bottom wall 78 and parallel to each other.

[0123] The first end wall 84 may be a plate-shaped member connected to the ends of the first side wall 80 and the second side wall 82 , and may prevent the first clamping portion 44 and the second clamping portion 46 disposed between the first side wall 80 and the second side wall 82 from moving out of the base 76 from their positions.

[0124] The splicing end 86 can be a roughly "concave" shaped end formed by the ends of the first side wall 80, the second side wall 82 and the bottom wall 78 away from the first end wall 84, and can be spliced ​​with, for example, the splicing end 86 of another gas detection fixture 40 to form a gas detection fixture 40 with a longer length to detect a larger object 60 to be detected.

[0125] Fig.12 yes Fig.11 A partial enlarged schematic diagram of the gas detection fixture. Fig.12 As shown, in some embodiments, the base 76 includes a base slide rail 88 , which includes a butt end surface 90 exposed outside the splicing end 86 , and the first clamping portion 44 and the second clamping portion 46 can move along the base slide rail 88 .

[0126] This can facilitate the first clamping portion 44 and the second clamping portion 46 to slide smoothly on the base slide rail 88 of the spliced ​​gas detection fixture 40, such as sliding from one gas detection fixture 40 to another gas detection fixture 40 spliced ​​therewith.

[0127] According to the specific size of the object 60 to be detected, the splicing ends 86 of two or more gas detection fixtures 40 can be spliced ​​to meet the size requirements. The docking section 90 of the base slide rail 88 exposed to the outside of the splicing end 86 can facilitate the smooth splicing of the two or more base slide rails 88 in the gas detection fixture 40 after splicing into a longer base slide rail 88 along which the first clamping part 44 and the second clamping part 46 can move. In this way, according to the specific structure of the object 60 to be detected, the length of the gas detection fixture 40, the position and size of the through part 52 can be defined at any desired position by moving the first clamping part 44 and / or the second clamping part 46 to meet the structural requirements.

[0128] After being fixed to the receiving seat 45 , the first clamping portion 44 and the second clamping portion 46 can follow the receiving seat 45 to move along the base slide rail 88 .

[0129] Fig.13 Schematic diagram of a gas detection fixture according to some embodiments of the present invention. Fig.13 As shown, in some embodiments, the gas detection fixture 40 includes a base 76, which includes a bottom wall 78, a first side wall 80 extending from the bottom wall 78 and close to the first clamping portion 44, a second side wall 82 extending from the bottom wall 78 and close to the second clamping portion 46, a first end wall 84 connecting the first side wall 80 and the second side wall 82, and a second end wall 90 connecting the first side wall 80 and the second side wall 82, which together with the first end wall 84, the first side wall 80 and the second side wall 82 partially surround the first clamping portion 44 and the second clamping portion 46.

[0130] In this way, the first clamping portion 44 and the second clamping portion 46 can be prevented from moving out of the base 76 to prevent the smooth progress of the detection from being affected and causing damage to personnel and objects.

[0131] The second end wall 90 may be at the same height as the first end wall 84, the first side wall 80 and the second side wall 82, and the four may be lower than the first clamping portion 44 and the second clamping portion 46 of the same height, surround the lower portions of the first clamping portion 44 and the second clamping portion 46, and limit the positions of the first clamping portion 44 and the second clamping portion 46 to each other.

[0132] In some embodiments, the base 76 includes a base slide rail 88 , and the first clamping portion 44 and the second clamping portion 46 can reciprocate along the base slide rail 88 between the first end wall 84 and the second end wall 90 .

[0133] In this way, the first clamping portion 44 and the second clamping portion 46 can be moved as needed.

[0134] The length of the base slide rail 88 between the first end wall 84 and the second end wall 90, and the first side wall 80 and the second side wall 82 may be greater than the length of the first clamping portion 44 and the second clamping portion 46, so that the first clamping portion 44 and the second clamping portion 46 may have space to move. The lengths of the first clamping portion 44 and the second clamping portion 46 may be equal. The length of the first end wall 84 and the second end wall 90 between the first side wall 80 and the second side wall 82 may be slightly greater than or equal to the distance between the outer surface 50 and the opposite surface 70, so that the first clamping portion 44 and the second clamping portion 46 may slide along the base slide rail 88 toward the first end wall 84 and the second end wall 90, but will not move toward the first side wall 80 and / or the second side wall 82.

[0135] In some embodiments, the gas detection fixture 40 includes a base 76 and a moving member 92 . The base 76 supports the first clamping portion 44 and the second clamping portion 46 . The base 76 can move along with the moving member 92 .

[0136] In this way, the gas detection fixture 40 can be easily moved.

[0137] The moving member 92 may be one or more rollers located below the base 76 .

[0138] In some embodiments, there are a plurality of second clamping portions 46 , and at least one of the second clamping portions 46 can move relative to another second clamping portion 46 adjacent thereto to move away from or closer to each other.

[0139] In this way, the size and position of the clamping space 48 and the through portion 52 can be adjusted advantageously.

[0140] For example, when the size of the detected object 60 is relatively large, more second clamping portions 46 can be close to each other to form a larger clamping space 48 with the opposite first clamping portion 44. On the contrary, when the size of the detected object 60 is relatively small, some second clamping portions 46 can be separated, and the remaining relatively few second clamping portions 46 can form a smaller clamping space 48 with the opposite first clamping portion 44.

[0141] When they are far away from or close to each other, the adjacent second clamping portions 46 may also define a smaller or larger through portion 52 between them, or the through portion 52 between them may be eliminated when they are close enough.

[0142] In some embodiments, there are a plurality of first clamping portions 44 , and at least one of the first clamping portions 44 can move relative to another first clamping portion 44 adjacent thereto to move away from or closer to each other.

[0143] This can be helpful in adjusting the size and position of the clamping space 48 .

[0144] For example, when the size of the detected object 60 is relatively large, more first clamping portions 44 can be close to each other to form a larger clamping space 48 with the opposite second clamping portion 46. On the contrary, when the size of the detected object 60 is relatively small, some first clamping portions 44 can be separated, and the remaining relatively few first clamping portions 44 can form a smaller clamping space 48 with the opposite second clamping portion 46.

[0145] When they are far away from or close to each other, the adjacent first clamping parts 44 can also define smaller or larger through-parts (not shown) that penetrate the opposite surface 70 and the clamping space 48, or eliminate the through-parts between them when they are close enough. When there are protruding parts on both sides of the detected object 60, they can be accommodated by the through-parts 52 defined by the second clamping part 46 and the through-parts (not shown) defined by the first clamping part 44, respectively.

[0146] The gas detection fixture 40 involved in the embodiment of the present application can be used in combination with the gas detection device 10 involved in the embodiment of the present application when the volume of the detected object 60 needs to be limited, and can also be used in combination with other gas detection devices.

[0147] Similarly, the gas detection device 10 involved in the embodiment of the present application can be used in combination with the gas detection fixture 40 involved in the embodiment of the present application when the volume of the detected object 60 needs to be limited, and can also be used in combination with other gas detection fixtures, or used without a gas detection fixture.

[0148] Fig.14 Schematic diagram of the process of gas detection method according to some embodiments of the present invention. Fig.14 As shown, another aspect of the embodiment of the present invention relates to a gas detection method 100, which includes the following steps: 102, delivering gas to the detected object 60 at a first flow rate; 104, if the detected object 60 reaches a first set air pressure within a first set time, delivering gas to the detected object 60 at a second flow rate; 106, if the detected object 60 reaches a second set air pressure within a second set time, monitoring the air pressure stability state of the detected object 60; 108, if the air pressure of the detected object 60 is stable within a third set time, stopping delivering gas to the detected object 60 and detecting a reference air pressure of the detected object 60; and 110, if the detected object 60 reaches or is lower than the third set air pressure within a fourth set time, drawing a detection conclusion that the detected object 60 has a leakage defect.

[0149] This can facilitate simple and rapid detection of the integrity of the object 60 being detected.

[0150] Step 102 and step 104 may respectively correspond to the two gas supply states of low pressure and large flow intake and low pressure and high precision intake of the gas detection device 10. The first flow in step 102 may be greater than the second flow in step 104 to quickly and accurately inflate the detected object 60.

[0151] Step 106 may correspond to the pressure stabilization state of the gas detection device 10, wherein after reaching the second set pressure within the second set time, the pressure is maintained. If the detected object 60 is complete and has no leakage defects, the gas flow rate may be small. If the detected object 60 is incomplete and has a leakage defect, the gas flow rate may be small or large depending on the size of the leakage defect.

[0152] Steps 108 and 110 may correspond to the detection state of the gas detection device 10, wherein "stable air pressure" allows the air pressure to fluctuate to a certain extent. For example, the air pressure may fluctuate within the range of ±2% of the second set air pressure. Alternatively, if the air pressure reaches the range of ±2% of the second set air pressure within the third set time, and may occasionally be greater than the range of ±2%, but does not continuously exceed ±5% of the second set air pressure for a certain period of time (for example, 30 seconds), it is considered that "the air pressure is stable within the third set time". The second set air pressure may vary depending on the object 60 being detected.

[0153] In some embodiments, the detected object 60 is in a volume-restricted state.

[0154] This can be beneficial for short detection time and high sensitivity.

[0155] The object 60 to be inspected will not expand indefinitely due to its limited volume, the amount of gas required to be filled is less than the nominal volume of the object 60 to be inspected, the inflation time is short, and leakage defects that cause leakage are relatively easier to detect.

[0156] The object 60 to be detected can be “volume-limited” by, for example, folding or inserting it into, for example, a gas detection fixture 40 .

[0157] In some embodiments, the volume of gas delivered to the detected object 60 is smaller than the nominal volume of the detected object 60 .

[0158] This can help detect the integrity of the object 60 using a small amount of gas and a shorter detection time.

[0159] In some embodiments, the nominal volume of the detected object 60 is greater than or equal to 5 ml.

[0160] In this way, it is advantageous to use the gas detection method 100 to detect the object 60 with a nominal volume greater than or equal to 5 ml.

[0161] In some embodiments, the first flow rate is in a range of 1 L / min to 1000 L / min, or 20 L / min to 200 L / min.

[0162] This can help to quickly deliver gas to the object 60 being detected, which can shorten the detection time.

[0163] In some embodiments, the gas includes one or more of air, nitrogen, carbon dioxide, and helium.

[0164] In this way, the operation of the gas detection method 100 is less likely to be restricted by gas, and can be applied in more scenarios.

[0165] The air can be compressed air, which is easy to obtain and store and has almost no impact on the environment. Therefore, the embodiments of the present application using air or compressed air are less restricted by gas acquisition, storage, environment, etc. and have wider applicability.

[0166] In some embodiments, the first set gas pressure is in the range of 10 mbar to 1000 mbar, or 10 mbar to 10000 mbar.

[0167] In this way, it is advantageous to deliver gas to the detected object 60 at a low pressure, and the requirements for equipment are relatively low.

[0168] In some embodiments, step 104 includes exiting the detection if the detected object 60 does not reach the first set air pressure within the first set time.

[0169] This can help save testing procedures and shorten the testing time.

[0170] If the detected object 60 does not reach the first set air pressure within the first set time, it means that the detected object 60 may have a leakage defect, causing the internal air pressure to be lower than the first set air pressure, and there is no need to perform subsequent detection steps.

[0171] In some embodiments, the second flow rate is less than the first flow rate.

[0172] This can facilitate precise inflation of the detected object 60 after rapid inflation.

[0173] In some embodiments, the second flow rate is a positive value or a negative value.

[0174] In this way, it is helpful to freely choose inflation or deflation according to the downstream air pressure.

[0175] In some embodiments, the second flow rate is in a range of 1 L / min to 10 L / min.

[0176] This can facilitate the small flow rate precision inflation in step 104 .

[0177] In some embodiments, the first set air pressure is in a range from 10% to 200% of the second set air pressure.

[0178] This can facilitate the combination of low-pressure rapid inflation and high-precision inflation, and is easy to operate and highly feasible.

[0179] For example, in step 102, the object to be detected 60 is inflated through the micro-pressure and large-flow pressure regulating valve 28 to reach a first set air pressure (such as 10%-200% of the second set air pressure), triggering the valve conversion, and then proceeding to step 104 to continue inflating (or exhausting) the object to be detected 60 using the precision pressure regulating valve 34.

[0180] For example, the following two situations can be assumed. Situation 1: To detect a bag (the object to be detected 60) with 50 mbar (the second set air pressure): After starting the gas detection equipment 10, the micro-pressure and large-flow pressure regulating valve 28 is opened to quickly inflate the bag. When the second pressure sensor 24 senses the first set air pressure (depending on the specific setting parameters. Assume that the internal logic is set to 90% of the second set air pressure in this example), that is, when the sensed pressure reaches 50 mbar*90%=45 mbar, the valve switching is triggered, and the gas path is transferred from the micro-pressure and large-flow pressure regulating valve 28 to the precision pressure regulating valve 34, and the gas is continued to be replenished until the set 50 mbar is reached.

[0181] Situation 2: To detect a bag (the object to be detected 60) with 50 mbar (the second set air pressure): After starting the gas detection equipment 10, the micro-pressure and high-flow pressure regulating valve 28 is opened to quickly inflate the bag. When the second pressure sensor 24 senses the first set air pressure (depending on the specific setting parameters. Assume that the internal logic is set to 200% of the second set air pressure in this example), that is, when the sensed pressure reaches 50 mbar*200%=100 mbar, the valve switching is triggered, and the gas circuit is transferred from the micro-pressure and high-flow pressure regulating valve 28 to the precision pressure regulating valve 34 to continue to replenish gas. Under this condition, the valve will not continue to replenish gas, but will actively discharge gas until the set pressure of 50 mbar is reached.

[0182] In some embodiments, step 106 includes exiting the detection if the detected object 60 does not reach the second set air pressure within the second set time.

[0183] This can help save testing procedures and shorten testing time.

[0184] If the detected object 60 does not reach the second set air pressure within the second set time, it means that the detected object 60 may have a leakage defect, causing the internal air pressure to be lower than the second set air pressure, and there is no need to perform subsequent detection steps.

[0185] In some embodiments, the third set time is in the range of 60 seconds to 360 seconds.

[0186] This can help the gas detection method 100 to be shorter in time.

[0187] In some embodiments, step 108 includes that if the change value of the air pressure of the detected object 60 relative to the second set air pressure within the third set time is less than the change threshold, and / or the duration of being greater than the change threshold is shorter than the time threshold, then the air pressure of the detected object 60 is stable within the third set time.

[0188] This can help to ensure accurate detection results.

[0189] The unstable air pressure of the detected object 60 may not only be caused by leakage defects, but also by temperature changes, deformation of the detected object 60, etc., which may cause the internal pressure of the detected object 60 to fluctuate. Therefore, it is possible that the detected object 60 is intact, but its internal pressure fluctuates due to factors such as temperature and deformation, which is manifested as a certain degree of pressure change of the detected object 60 within the third set time.

[0190] The change threshold can be set according to the detection accuracy. In some embodiments, the change threshold is ±5%.

[0191] This can help to achieve higher detection accuracy.

[0192] The time threshold can be preset. In some embodiments, the time threshold is 30 seconds.

[0193] This can help shorten the detection time.

[0194] In some embodiments, step 108 includes, if the air pressure of the detected object 60 is stable within the third set time, detecting a reference air pressure of the detected object 60 at the end of the third set time.

[0195] In this way, it is helpful to eliminate the influence of other factors such as temperature and deformation on the integrity detection of the object 60 to be detected, and then enter the detection step 110.

[0196] The reference air pressure may be the real-time air pressure data of the detected object 60 detected at the end of the third set time.

[0197] The end of the third set time may include a period of time before the third set time expires, such as 0-10 seconds before the third set time expires.

[0198] In some embodiments, step 108 includes exiting the detection if the air pressure of the detected object 60 is unstable within a third set time.

[0199] This can help save testing procedures and shorten testing time.

[0200] If the air pressure of the detected object 60 is unstable within the third set time, it means that the detected object 60 may have a leakage defect, causing the air pressure inside it to change, and there is no need to perform subsequent detection steps.

[0201] The embodiment of the present invention can use the pressure decay method to detect the integrity of the detected object 60, and can judge the integrity of the detected object 60 of the corresponding type and nominal volume by the linear regression equation of the leakage curve of the detected object 60 of different types and different nominal volumes. In some embodiments, the fourth set time, the reference air pressure, and the third set air pressure have a linear equation relationship: reference air pressure-third set air pressure=k*fourth set time+b, where k is the leakage slope corresponding to the detected object 60, and b is the equation derivation constant. The leakage slope k and the equation derivation constant b can be obtained by experiments or provided by the manufacturer of the detected object 60.

[0202] This can facilitate obtaining integrity detection data by correlating air pressure and time.

[0203] The detection accuracy of the embodiment of the present invention may be affected by two factors:

[0204] 1. The larger the volume of the detection cavity of the detected object 60, the smaller the pressure change rate of the detected object 60 per unit time, that is, the detection accuracy is relatively low;

[0205] 2. The larger the leakage aperture of the detected object 60, the greater the pressure change rate per unit time of the detected object 60, and the higher the detection accuracy. Conversely, the smaller the leakage aperture of the detected object 60, the smaller the pressure change rate per unit time, which means the detection accuracy is relatively low.

[0206] For example, when the volume of the detected object 60 itself is small, the volume of the cavity expanded in the gas detection fixture will also be correspondingly small, and the change value of its pressure decay rate per unit time will be large, making it easy to detect a smaller leakage aperture. Conversely, when the volume of the detected object 60 itself is large, the volume of the cavity expanded in the gas detection fixture will also be correspondingly large, and the change of its pressure decay rate per unit time will not be obvious, and the leak aperture that can be detected will be larger.

[0207] Theoretically, as long as the time is long enough, even if the volume of the detected object 60 is relatively large, the pressure decay value of a small leak aperture can be detected. However, in actual processes, this may not be ideal, because a long wait usually means high costs.

[0208] In some embodiments, the detected object 60 is a two-dimensional or three-dimensional disposable liquid storage bag with different nominal volumes. The two-dimensional disposable liquid storage bag is usually mainly composed of two plastic films, and the three-dimensional disposable liquid storage bag is usually mainly composed of three or more plastic films. The type, nominal volume, third set time, fourth set time, qualified limit (the difference between the reference air pressure and the third set air pressure) and detection accuracy of the detected object 60 are shown in Table 1 below.

[0209]

[0210] As can be seen from Table 1, in the embodiment of the present application, for the test object 60 with a nominal volume of 200 liters or less, a clear pressure decay signal for detecting a 30-micron leak hole can be obtained in about 13 minutes; for a larger bag, even if a 30-micron leak hole cannot be detected in about 13 minutes, a clear pressure decay signal for detecting a 75-micron leak hole can be obtained. Further experiments show that if the time is extended to 20-30 minutes, a 30-micron leak defect of the test object 60 with a nominal volume greater than 200 liters can be detected.

[0211] The detection accuracy and qualified limit can be selected according to the risk level of the detected object 60, so as to determine the third set air pressure according to the reference air pressure, that is, the third set air pressure = reference air pressure - qualified limit, and then detect whether the detected object 60 reaches or exceeds the third set air pressure in the fourth set time that meets the linear equation, qualified limit = k* fourth set time + b, so as to achieve a two-way balance between detection efficiency and process safety. For example, for large bags with lower risks, the detection accuracy can be compromised and 75 micron resolution detection can be selected; for large bags with higher risks, the detection time can be compromised and the detection accuracy of 30 microns can be achieved by extending the detection time.

[0212] Examples of risk assessment include: disposable pharmaceutical systems close to the upstream of the pharmaceutical process, which have relatively low risks; disposable pharmaceutical systems close to the downstream process section of the pharmaceutical process for sterilization and filtration, which have relatively high risks; disposable pharmaceutical systems containing low added value, which have relatively low risks; and disposable pharmaceutical systems containing high added value, which have relatively high risks. The requirements for integrity testing accuracy can be adjusted based on process requirements and risk levels.

[0213] In some embodiments, the fourth set time is in the range of 110 seconds to 420 seconds.

[0214] This can help complete the detection in a shorter time.

[0215] In some embodiments, the difference between the reference pressure and the third set pressure is in the range of 1 mbar to 2 mbar.

[0216] This can help obtain a clearer pressure decay signal.

[0217] In some embodiments, the size of the leakage defect ranges from a few microns to hundreds of microns.

[0218] This can help achieve a two-way balance between detection efficiency and process safety.

[0219] For example, the size of the leakage defect may be in the range of 5 micrometers to 300 micrometers, or in the range of 30 micrometers to 75 micrometers. When the leakage defect is a hole, the size of the leakage defect may be the hole diameter.

[0220] In some embodiments, step 110 includes, if the detected object 60 does not reach or exceed the third set air pressure within a fourth set time, then obtaining a detection conclusion that the detected object 60 has no leakage defect.

[0221] If there is a leakage defect, the air pressure of the detected object 60 decays over time. As time goes by, the decay value increases. If the detected object 60 does not reach or exceed the third set air pressure within the fourth set time, it is highly likely that the detected object 60 has no leakage defect.

[0222] In some embodiments, the gas detection method 100 includes step 112 , exhausting the detected object 60 .

[0223] This can be helpful, for example, in removing the detected object 60 from the gas detection fixture after the detection is completed, and / or preventing the detected object 60 from exploding due to pressure-induced operation during use.

[0224] Another aspect of an embodiment of the present invention relates to a storage medium storing computer instructions, which, when executed, execute the steps of the gas detection method 100 as described in the present application, and for details, refer to the description of the relevant parts of steps 102 to 112.

[0225] Another aspect of an embodiment of the present invention relates to an electronic device, which includes a memory and a processor, wherein the memory stores computer instructions that can be executed by the processor, and when the processor executes the computer instructions, the steps of the gas detection method 100 as described above are executed, and specific reference may be made to the description of the relevant parts of steps 102 to 112.

[0226] All or part of the steps in the various methods of the embodiments of the present application may be completed by instructing related hardware through a program, and the program may be stored in a computer-readable storage medium.

[0227] Storage media, memory, and computer-readable storage media may include non-volatile memory or non-transitory memory, etc. Storage media, memory, and computer-readable storage media may include USB flash drives, mobile hard disks, read-only memories (ROM), random access memories (RAM), disks or optical disks, etc.

[0228] Fig.15 Schematic diagram of the structure of a gas detection device according to some embodiments of the present invention. Fig.15 As shown, another aspect of the embodiment of the present invention relates to a gas detection device 140, which includes: a first gas delivery unit 142, which can deliver gas to a detected object 60 at a first flow rate; a second gas delivery unit 144, if the detected object 60 reaches a first set air pressure within a first set time, the second gas delivery unit 144 can deliver gas to the detected object 60 at a second flow rate; a monitoring unit 146, if the detected object 60 reaches a second set air pressure within a second set time, the monitoring unit 146 monitors the air pressure state of the detected object 60; a detection unit 148, if the air pressure of the detected object 60 is stable within a third set time, the gas delivery to the detected object 60 is stopped, and the detection unit 148 detects the reference air pressure of the detected object 60; and a control unit 150, which communicates with the first gas delivery unit 142, the second gas delivery unit 144, the monitoring unit 146, and the detection unit 148, if the detected object 60 reaches or is lower than the third set air pressure within a fourth set time, the control unit 150 draws a detection conclusion that the detected object 60 has a leakage defect.

[0229] The gas detection device 140 may be implemented by the configuration of the gas detection device 10 or by other configurations.

[0230] In some embodiments, the first gas delivery unit 142 may include a gas input passage 12, a first pressure regulating valve 14, a first pressure sensor 16, a first gas delivery passage 18, a gas output interface 22, a second pressure sensor 24, and a gas circuit control component 26. When the detection starts, gas can be delivered at a first flow rate to the object to be detected 60 connected to the gas output interface 22 and clamped by the gas detection fixture 40.

[0231] The second gas delivery unit 144 may include a gas input passage 12, a first pressure regulating valve 14, a first pressure sensor 16, a second gas delivery passage 20, a gas output interface 22, a second pressure sensor 24, and a gas circuit control component 26. When the detected object 60 reaches the first set air pressure within the first set time, the gas is delivered at a second flow rate to the detected object 60 connected to the gas output interface 22 and clamped by the gas detection fixture 40.

[0232] The monitoring unit 146 may include a second pressure sensor 24 , and starts monitoring the air pressure state of the detected object 60 when the detected object 60 reaches a second set air pressure within a second set time.

[0233] The detection unit 148 may include a second pressure sensor 24 for detecting a reference air pressure of the detected object 60 when a third set time for the air pressure of the detected object 60 to be stable ends.

[0234] The control unit 150 may include software, hardware, or any combination of the two, and may receive an instruction to start detection, trigger the first gas delivery unit 142 to deliver gas to the detected object 60 at a first flow rate, obtain a signal that the detected object 60 reaches a first set air pressure within a first set time, trigger the second gas delivery unit 144 to deliver gas to the detected object 60 at a second flow rate, obtain a signal that the detected object 60 reaches a second set air pressure within a second set time, trigger the monitoring unit 146 to monitor the stable state of the air pressure of the detected object 60, obtain a signal that the air pressure of the detected object 60 is stable within a third set time, trigger the detection unit 148 to detect the reference air pressure of the detected object 60, obtain a signal that the detected object 60 reaches or is lower than the third set air pressure within a fourth set time, and draw a detection conclusion that the detected object 60 has a leakage defect.

[0235] The control unit 150 may terminate the detection, stop supplying gas to the detected object 60, and stop triggering subsequent steps when obtaining a signal indicating that the detected object 60 does not reach the first set air pressure within the first set time.

[0236] The control unit 150 may terminate the detection, stop supplying gas to the detected object 60, and stop triggering subsequent steps when obtaining a signal that the detected object 60 does not reach the second set air pressure within the second set time.

[0237] The control unit 150 may terminate the detection and no longer trigger subsequent steps when obtaining a signal indicating that the air pressure of the detected object 60 is unstable within the third set time.

[0238] The control unit 150 can draw a detection conclusion that the detected object 60 has no leakage defect when obtaining a signal that the detected object 60 does not reach or exceed the third set air pressure within the fourth set time.

[0239] The control unit 150 may include a storage medium, a memory, and a processor. The first flow rate, the first set time, the first set air pressure, the second flow rate, the second set time, the second set air pressure, the third set time, the change threshold, the time threshold, and the fourth set time may be stored in the storage medium and the memory. The third set air pressure may be calculated by the processor according to the linear equation relationship with the fourth set time and the reference air pressure: reference air pressure-third set air pressure=k*the fourth set time+b.

[0240] The various specific embodiments described above and shown in the drawings are only used to illustrate the present invention, and are not the entire present invention. Within the scope of the basic technical concept of the present invention, any form of changes made by ordinary technicians in the relevant technical field to the present invention are within the protection scope of the present invention.

Claims

1. A gas detection fixture (40), characterized in that: include: Base (42); A first clamping portion (44) disposed on the base (42); as well as A second clamping portion (46) is disposed on the base (42), a clamping space (48) is defined between the second clamping portion (46) and the first clamping portion (44), the second clamping portion (46) comprises an outer surface (50) away from the first clamping portion (44) and a through portion (52) penetrating the outer surface (50) and the clamping space (48), there are a plurality of second clamping portions (46), at least one of the second clamping portions (46) can move relative to another second clamping portion (46) adjacent thereto to move away from or closer to each other.

2. The gas detection fixture (40) according to claim 1, characterized in that: At least one of the second clamping portions (46) can move away from another second clamping portion (46) adjacent thereto to define the through portion (52) therebetween.

3. The gas detection fixture (40) according to claim 2, characterized in that: It comprises a first slide rail (54) provided on the base (42), and at least one of the second clamping parts (46) can move along the first slide rail (54).

4. The gas detection fixture (40) according to claim 3, characterized in that: The base (42) comprises a receiving groove (56) which receives the first slide rail (54).

5. The gas detection fixture (40) according to claim 1, characterized in that: It comprises a second slide rail (58) provided on the base (42) and connected to the first clamping portion (44).

6. The gas detection fixture (40) according to claim 5, characterized in that: The base (42) comprises a receiving groove (56) which receives the second slide rail (58).

7. The gas detection fixture (40) according to claim 1, characterized in that: The distance (D) between the first clamping portion (44) and the second clamping portion (46) opposite thereto is smaller than the minimum external dimension (S) corresponding to the nominal volume of the detected object (60).

8. The gas detection fixture (40) according to claim 1, characterized in that: The distance (D) between the first clamping portion (44) and the second clamping portion (46) opposite thereto is in the range of 0.5 cm to 5 cm.

9. The gas detection fixture (40) according to claim 1, characterized in that: It includes a retaining portion (62) which can maintain the relative position of the first clamping portion (44) and the second clamping portion (46).

10. The gas detection fixture (40) according to claim 9, characterized in that: The retaining portion (62) comprises a locking member (64) that cooperates with the first clamping portion (44) and the second clamping portion (46).

11. The gas detection fixture (40) according to claim 10, characterized in that: The retaining portion (62) comprises a first groove (66) and a second groove (68) which are respectively provided on the first clamping portion (44) and the second clamping portion (46) and cooperate with the locking member (64).

12. The gas detection fixture (40) according to claim 10, characterized in that: The first clamping portion (44) comprises an opposite surface (70) opposite to the outer surface (50), and the locking member (64) comprises a first locking portion (72) and a second locking portion (74) respectively protruding from the opposite surface (70) and the outer surface (50).

13. The gas detection fixture (40) according to claim 1, characterized in that: At least one of the second clamping portions (46) and another second clamping portion (46) adjacent thereto respectively comprise a first edge through hole (75) and a second edge through hole (77), and the second edge through hole (77) is opposite to and communicates with the first edge through hole (75) to define the through portion (52).

14. The gas detection fixture (40) according to claim 1, characterized in that: It includes a base (76) which includes a bottom wall (78), a first side wall (80) extending from the bottom wall (78) and close to the first clamping portion (44), a second side wall (82) extending from the bottom wall (78) and close to the second clamping portion (46), a first end wall (84) connecting the first side wall (80) and the second side wall (82), and a splicing end (86) which can be spliced ​​with another gas detection fixture (40).

15. The gas detection fixture (40) according to claim 14, characterized in that: The base (76) comprises a base slide rail (88), which comprises a butt end surface exposed outside the splicing end (86), and the first clamping portion (44) and the second clamping portion (46) can move along the base slide rail (88).

16. The gas detection fixture (40) according to claim 1, characterized in that: The base (76) includes a bottom wall (78), a first side wall (80) extending from the bottom wall (78) and adjacent to the first clamping portion (44), a second side wall (82) extending from the bottom wall (78) and adjacent to the second clamping portion (46), a first end wall (84) connecting the first side wall (80) and the second side wall (82), and a second end wall connecting the first side wall (80) and the second side wall (82), which together with the first end wall (84), the first side wall (80) and the second side wall (82) partially surrounds the first clamping portion (44) and the second clamping portion (46).

17. The gas detection fixture (40) according to claim 16, characterized in that: The base (76) comprises a base slide rail (88), and the first clamping portion (44) and the second clamping portion (46) can reciprocate between the first end wall (84) and the second end wall along the base slide rail (88).

18. The gas detection fixture (40) according to claim 1, characterized in that: It comprises a base (76) and a moving member (92), wherein the base (76) supports the first clamping portion (44) and the second clamping portion (46), and the base (76) can move along with the moving member (92).

19. The gas detection fixture (40) according to claim 1, characterized in that: When at least one of the second clamping portions (46) moves relative to another second clamping portion (46) adjacent thereto, the distance (D) between the first clamping portion (44) and the opposite second clamping portion (46) remains substantially unchanged.

20. The gas detection fixture (40) according to claim 1, characterized in that: The direction in which at least one of the second clamping portions (46) moves relative to another second clamping portion (46) adjacent thereto is parallel to the first clamping portion (44).

21. The gas detection fixture (40) according to any one of claims 1 to 20, characterized in that: There are a plurality of first clamping portions (44), and at least one of the first clamping portions (44) can move relative to another first clamping portion (44) adjacent thereto to move away from or closer to each other.

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