A sample loading device, a sampling apparatus and a sampling method

Abstract

The application provides a sample feeding device, a sampling device and a sampling method, and relates to the field of medical apparatuses. The sample feeding device comprises a base, a first driving mechanism and a detection assembly. The base has a feeding channel, and the feeding channel has an inlet end. The sample seat has a plurality of placement positions for placing samples. The first driving mechanism is used for driving the sample seat from the inlet end along the feeding channel to a sampling position, so that the sampling module takes out the samples from the placement positions. The detection assembly is used for detecting whether the placement positions have samples, and the sampling module responds to the detection result of the detection assembly. The sample feeding device detects whether the placement positions have samples through the detection assembly, determines which placement positions have samples and which placement positions do not have samples, so that the sampling module can accurately move to the placement positions with samples when sampling, and no empty action occurs. The sample feeding device avoids the waste of time caused by the empty action of the sampling module, improves the sampling efficiency of the sampling module, and improves the analysis efficiency of biological samples.

Description

Technical Field

[0001] The present application relates to the field of medical devices, and more specifically, to a sampling device, a sampling apparatus, and a sampling method. Background Art

[0002] In analytical laboratories, especially in in vitro diagnostics, biological samples are analyzed to determine a patient's physiological and biochemical status. The efficiency of analyzing biological samples can impact a patient's condition, but currently, the efficiency is low. Summary of the Invention

[0003] The purpose of the embodiments of the present application is to provide a sample loading device, a sampling device and a sampling method, which are intended to improve the problem of low analysis efficiency of biological samples in related technologies.

[0004] In a first aspect, an embodiment of the present application provides a loading device, comprising a base, a first driving mechanism and a detection component, wherein the base has a feed channel for moving a sample holder, the feed channel has an inlet end, and the sample holder has a plurality of placement positions for placing samples; the first driving mechanism is connected to the base, and the first driving mechanism is used to drive the sample holder from the inlet end along the feed channel to a sampling position, so that a sampling module can take the sample out of the placement position; the detection component is connected to the base, and the detection component is used to detect whether there is a sample at the placement position, and the sampling module responds to the detection result of the detection component.

[0005] In the above technical solution, the base has a feed channel. The operator only needs to place the sample holder at the inlet end of the feed channel, and the first drive mechanism can drive the sample holder from the inlet end along the feed channel to the sampling position, thereby facilitating the sampling module to sample from the sampling position. Since the sample holder has multiple placement positions, when actually analyzing biological samples, not every placement position has a sample. In many cases, only some placement positions have samples. The sampling module in the prior art will sample multiple placement positions in sequence. When the sampling module moves to a placement position without a sample, an idle movement will occur, wasting time and resulting in low sampling efficiency. The loading device provided in the embodiment of the present application detects whether the placement position has a sample by setting a detection component to determine which placement positions have samples and which placement positions do not have samples, so that the sampling module can accurately move to the placement position with a sample when sampling, without idle movement, avoiding the time wasted by the idle movement of the sampling module, improving the sampling efficiency of the sampling module, and improving the analysis efficiency of the biological sample.

[0006] As an optional technical solution of an embodiment of the present application, the detection component includes multiple rows of detection units arranged along the extension direction of the feed channel, and each row of detection units is used to detect whether there are samples in multiple placement positions in a sample holder.

[0007] In the above technical solution, samples are generally placed in sample tubes, and the placement positions are capable of receiving the sample tubes and thus achieving sample placement. Since sample tubes come in multiple sizes, the sample holders are also provided with multiple sizes. The number and position of placement positions provided on sample holders of different sizes may vary. Therefore, by providing multiple rows of detection units, it is possible to detect whether the placement positions of sample holders of various sizes contain samples, thereby improving the adaptability of the sample loading device to sample tubes of different sizes.

[0008] As an optional technical solution of an embodiment of the present application, each row of the detection units includes a plurality of detection units arranged at equal intervals, and the interval between two adjacent detection units in a row of detection units is different from the interval between two adjacent detection units in another row of detection units adjacent to the row of detection units.

[0009] In the above technical solution, the distance between two adjacent placement positions of sample holders of different specifications is generally different. By making the interval between two adjacent detection units in one row of detection units different from the interval between two adjacent detection units in another row of detection units adjacent to the first row of detection units, it is possible to adapt to sample holders of different specifications, so as to detect whether there are samples in the placement positions of sample holders of various specifications, thereby improving the adaptability of the sample loading device to sample tubes of different specifications.

[0010] As an optional technical solution of the embodiment of the present application, the detection unit is a photoelectric sensor, and the placement position is correspondingly provided with a detection hole that can transmit the light signal emitted by the photoelectric sensor.

[0011] In the above technical solution, the photoelectric sensor can emit a light signal to the detection hole. When a sample is placed at the placement position, the sample blocks the light signal, causing the photoelectric sensor to generate a first signal that the sample is present. When the sample is not placed at the placement position, the light signal is not blocked, causing the photoelectric sensor to generate a second signal that the sample is not present.

[0012] As an optional technical solution of an embodiment of the present application, the sample loading device includes a first alarm, which responds to the detection result of the detection component to alarm when the detection component detects that there is no sample in at least one of the placement positions.

[0013] In the above technical solution, by setting the first alarm, the first alarm can alarm when the detection component detects that there is no sample in at least one placement position, so as to warn the operator whether there is any missed sample.

[0014] As an optional technical solution of an embodiment of the present application, the base includes a bottom wall for supporting the sample holder and a side wall connected to the bottom wall, the bottom wall and the side wall forming the feed channel; the first driving mechanism includes a hook, a movable part and a driving unit, the hook is arranged on the movable part, the movable part is movably arranged on the side wall, the driving unit is connected to the movable part, the hook is used to avoid the sample holder when the driving unit drives the movable part to move in the opposite direction along the extension direction of the feed channel, and the hook is also used to hook on the side of the sample holder when the driving unit drives the movable part to move in the forward direction along the extension direction of the feed channel, so as to drive the sample holder from the inlet end along the feed channel to the sampling position.

[0015] In the above technical solution, if the movable part is to be positioned on the bottom wall, an escape groove for the movable part must be provided on the bottom wall. If a foreign object falls into the escape groove or becomes stuck in the drive unit, such as if a foreign object becomes stuck in a gear or pulley, the sample loading device will malfunction and become inoperable. By positioning the movable part on the side wall, the risk of foreign objects entering the side wall and causing a malfunction of the first drive mechanism can be reduced, as the side wall is less likely to contain foreign objects than the bottom wall. Furthermore, the hook can hook onto the side of the sample holder when the drive unit drives the movable part to move in the forward direction along the feed channel, thereby driving the sample holder from the inlet end along the feed channel to the position to be sampled, thereby achieving the transfer of the sample holder. The hook can also avoid the sample holder when the driving unit drives the movable part to move in the opposite direction along the extension direction of the feed channel. In this way, when the hook drives a sample holder from the inlet end to the sampling position, it can immediately return to the inlet end to transfer the next sample holder without being blocked by the next sample holder during the return process, thereby reducing the time for the first driving mechanism to drive the sample holder from the inlet end to the sampling position, improving the loading efficiency of the sample loading device, and thus improving the analysis efficiency of the biological sample.

[0016] As an optional technical solution of an embodiment of the present application, the hook claw has a first position and a second position, and the hook claw is used to avoid the sample holder when it is in the first position, and the hook claw is also used to hook on the side of the sample holder when it is in the second position; the first driving mechanism also includes a reset member, which is connected to the hook claw and the movable member, and the reset member is used to reset the hook claw from the first position to the second position.

[0017] In the above technical solution, when the driving unit drives the movable member to move in the opposite direction along the extension direction of the feed channel, the hook claw switches from the second position to the first position, and the reset member accumulates elastic force. The elastic force is used to reset the hook claw from the first position to the second position after the hook claw moves away from the sample holder, so that the hook claw can be hooked on the side of the sample holder when the driving unit drives the movable member to move in the forward direction along the extension direction of the feed channel.

[0018] As an optional technical solution of an embodiment of the present application, the loading device includes an in-place detection member, which is installed on the base. The in-place detection member is used to detect whether the sample holder has reached the position to be sampled, and the first driving mechanism responds to the in-place detection member.

[0019] In the above technical solution, the first drive mechanism drives the sample holder until the sample holder triggers the in-place detection element, indicating that the sample holder has reached the sampling position. At this point, the first drive mechanism can begin preparing to move the next sample holder. The in-place detection element improves the accuracy of the first drive mechanism in driving the sample holder to the sampling position, ensuring the accurate and reliable relative position of the sample holder and the sampling module, thereby improving the sampling efficiency of the sampling module and the efficiency of biological sample analysis.

[0020] As an optional technical solution of an embodiment of the present application, the base also has a discharge channel and a transfer channel, the discharge channel is used for the movement of the sample holder after the sampling module has taken samples, and the discharge channel has an outlet end; the transfer channel is connected to the feed channel and the discharge channel; the loading device also includes a second drive mechanism and a third drive mechanism, the second drive mechanism is connected to the base, and the second drive mechanism is used to transfer the sample holder after the sampling module has taken samples from the position to be sampled along the transfer channel to the discharge channel; the third drive mechanism is connected to the base, and the third drive mechanism is used to drive the sample holder transferred by the second drive mechanism along the discharge channel to the outlet end.

[0021] In the above technical solution, a second drive mechanism facilitates the transfer of the sample receptacle after sampling by the sampling module from the sampling position along the transfer channel to the discharge channel. A third drive mechanism facilitates the drive of the sample receptacle transferred by the second drive mechanism along the discharge channel to the outlet. The operator can remove the sample receptacle after sampling by the sampling module at the outlet, ensuring that sampling and feeding processes do not interfere with each other, thereby accelerating the loading efficiency of the sample loading device and improving the efficiency of biological sample analysis.

[0022] As an optional technical solution of an embodiment of the present application, the feed channel and the discharge channel are arranged side by side, and the extension direction of the transfer channel is perpendicular to the extension directions of the feed channel and the discharge channel.

[0023] In the above technical solution, by arranging the feed channel and the discharge channel side by side and making the extension direction of the transfer channel perpendicular to the extension direction of the feed channel and the discharge channel, it is beneficial to reduce the length of the loading device so that the loading device can adapt to the size of the analysis chamber.

[0024] As an optional technical solution of the embodiment of the present application, the sample loading device further includes a discharge drawer, which is movably arranged at the outlet end, and the discharge drawer is used to accommodate the sample holder driven by the third driving mechanism.

[0025] In the above technical solution, by setting up a discharge drawer, the sample seats after sampling by the sampling module can be temporarily stored. When the discharge drawer is full of sample seats after sampling by the sampling module, the sample seats in the discharge drawer can be cleaned uniformly, which is beneficial to reduce the frequency of cleaning the sample seats and reduce the labor intensity of the operators.

[0026] As an optional technical solution of an embodiment of the present application, the loading device includes a full material detection component and a second alarm. The full material detection component is installed on the discharge drawer, and the full material detection component is used to detect whether the discharge drawer is full; the second alarm responds to the detection result of the full material detection component to alarm when the discharge drawer is full.

[0027] In the above technical solution, a full material detection member is provided to facilitate detection of whether the discharge drawer is full of material. The second alarm can sound an alarm when the discharge drawer is full of material, alerting the operator to clean the discharge drawer.

[0028] As an optional technical solution of an embodiment of the present application, the loading device also includes a feed drawer, which is movably arranged at the inlet end. The feed drawer is used to place the sample holder before the sampling module takes samples, and the first driving mechanism is used to drive the sample holder in the feed drawer along the feed channel to the position to be sampled.

[0029] In the above technical solution, by providing a feed drawer, multiple sample holders before sampling by the sampling modules can be placed in the feed drawer simultaneously, and the first drive mechanism automatically moves these sample holders to the sampling position in sequence. This reduces the frequency of operators placing sample holders before sampling by the sampling modules, thereby reducing the operator's labor intensity.

[0030] In a second aspect, an embodiment of the present application further provides a sampling device, which includes the above-mentioned sample loading device and a sampling module, wherein the sampling module is electrically connected to the detection component, and the sampling module is used to respond to the detection result of the detection component.

[0031] In a third aspect, an embodiment of the present application further provides a sampling method, which is based on the above-mentioned sampling device, and includes placing the sample holder before sampling by the sampling module into the inlet end; driving the sample holder from the inlet end along the feed channel to the position to be sampled by the first driving mechanism; in the process of driving the sample holder from the inlet end along the feed channel to the position to be sampled by the first driving mechanism, detecting whether there is a sample at the placement position by the detection component; and the sampling module sampling from the placement position with the sample in response to the detection result of the detection component. BRIEF DESCRIPTION OF THE DRAWINGS

[0032] In order to more clearly illustrate the technical solutions of the embodiments of the present application, the following is a brief introduction to the drawings required for use in the embodiments. It should be understood that the following drawings only show certain embodiments of the present application and therefore should not be regarded as limiting the scope. For ordinary technicians in this field, other relevant drawings can be obtained based on these drawings without creative work.

[0033] Figure 1 A schematic diagram of the structure of the sample loading device provided in an embodiment of the present application;

[0034] Figure 2 A schematic structural diagram of the first sample holder provided in an embodiment of the present application;

[0035] Figure 3 A schematic structural diagram of the second sample holder provided in an embodiment of the present application;

[0036] Figure 4 A schematic structural diagram of a sample loading device (loaded with a sample holder) provided in an embodiment of the present application;

[0037] Figure 5 A schematic structural diagram of a first driving mechanism provided in an embodiment of the present application;

[0038] Figure 6 A schematic diagram of the connection between the hook and the movable member provided in an embodiment of the present application;

[0039] Figure 7 A schematic block diagram of the connection between the detection assembly and various components provided in an embodiment of the present application;

[0040] Figure 8 A schematic block diagram of a sampling device provided in an embodiment of the present application;

[0041] Figure 9 A schematic flow chart of the sampling method provided in an embodiment of the present application.

[0042] Icons: 10- loading device; 20- sampling module; 30- sampling device; 100- base; 101- bottom wall; 102- side wall; 110- feeding channel; 111- inlet end; 112- sampling position; 120- transfer channel; 130- discharging channel; 131- outlet end; 200- first driving mechanism; 210- driving unit; 211- first motor; 212- first screw rod; 220- moving part; 221- connecting part; 222- extension part; 230- hook claw; 240- first slide rail; 250- complex Positioning part; 300-detection component; 310-detection unit; 320-controller; 330-first alarm; 340-second alarm; 400-in-place detection part; 500-second driving mechanism; 510-second motor; 520-second screw rod; 530-sliding seat; 550-second slide rail; 600-third driving mechanism; 700-discharging drawer; 710-full material detection part; 800-feeding drawer; 900-sample holder; 910-side; 920-bottom; 930-blood collection tube; 940-ordinary sample tube. DETAILED DESCRIPTION

[0043] To make the objectives, technical solutions, and advantages of the embodiments of the present application more clear, the technical solutions in the embodiments of the present application will be clearly and completely described below in conjunction with the accompanying drawings of the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, not all of the embodiments. Generally, the components of the embodiments of the present application described and shown in the drawings herein can be arranged and designed in various different configurations.

[0044] Therefore, the following detailed description of the embodiments of the present application provided in the accompanying drawings is not intended to limit the scope of the present application for protection, but merely represents selected embodiments of the present application. All other embodiments obtained by persons of ordinary skill in the art based on the embodiments in the present application without creative work are within the scope of protection of the present application.

[0045] It should be noted that similar reference numerals and letters denote similar items in the following drawings, and therefore, once an item is defined in one drawing, it does not need to be further defined or explained in subsequent drawings.

[0046] In the description of the embodiments of the present application, it should be understood that the terms "center", "up", "down", "left", "right", "vertical", "horizontal", "inside", "outside", etc. indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, or are the orientations or positional relationships in which the product of the application is conventionally placed when in use, or are the orientations or positional relationships conventionally understood by those skilled in the art. They are only for the convenience of describing the present application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as a limitation on the present application.

[0047] Furthermore, the terms “first,” “second,” “third,” etc., are merely used for distinguishing descriptions and are not to be understood as indicating or implying relative importance.

[0048] In the description of the embodiments of the present application, it should also be noted that, unless otherwise expressly specified or limited, the terms "disposed," "installed," "connected," and "connected" should be understood in a broad sense. For example, they can refer to fixed connections, detachable connections, or integral connections; they can refer to mechanical connections or electrical connections; they can refer to direct connections or indirect connections through an intermediate medium; and they can refer to internal connections between two components. Those skilled in the art will understand the specific meanings of the above terms in this application based on the specific circumstances.

[0049] In analytical laboratories, especially in in vitro diagnostics, biological samples are analyzed to determine a patient's physiological and biochemical status. The efficiency of analyzing biological samples can impact a patient's condition, but currently, the efficiency is low.

[0050] The inventors discovered that the current low efficiency of biological sample analysis stems from the fact that, while the sample holder has multiple placement positions, not every position actually contains a sample during analysis; in many cases, only some positions contain a sample. Conventional sampling modules sequentially sample multiple positions, and when the sampling module reaches a position without a sample, this is a wasted movement, wasting time and resulting in low sampling efficiency.

[0051] Based on the above considerations, the inventors have designed a sample loading device after in-depth research. The sample loading device detects whether there is a sample at the placement position by setting a detection component, and determines which placement positions have samples and which placement positions do not have samples, so that the sampling module can accurately move to the placement position with the sample when sampling, and there will be no empty movement, avoiding the waste of time caused by empty movement of the sampling module, improving the sampling efficiency of the sampling module, and improving the analysis efficiency of biological samples.

[0052] Example

[0053] Please refer to Figures 1 to 4 , this embodiment provides a sample loading device 10, which includes a base 100, a first driving mechanism 200 and a detection component 300. The base 100 has a feed channel 110 for the sample holder 900 to move, and the feed channel 110 has an inlet end 111. The sample holder 900 has a plurality of placement positions for placing samples. The first driving mechanism 200 is connected to the base 100, and the first driving mechanism 200 is used to drive the sample holder 900 from the inlet end 111 along the feed channel 110 to the sampling position 112, so that the sampling module 20 can take the sample out from the placement position. The detection component 300 is connected to the base 100, and the detection component 300 is used to detect whether there is a sample at the placement position, and the sampling module 20 responds to the detection result of the detection component 300.

[0054] The base 100 serves as the supporting foundation for the sample loading device 10 and is the primary load-bearing component of the sample loading device 10. Most components of the sample loading device 10, such as the first drive mechanism 200 and the detection assembly 300, are mounted on the base 100. The base 100 includes a feed channel 110, which guides the sample holder 900, ensuring accurate movement from the inlet port 111 to the sampling position 112.

[0055] The first driving mechanism 200 is a driving mechanism for driving the sample holder 900 on which the sample is placed from the inlet end 111 along the feeding channel 110 to the position 112 to be sampled.

[0056] The detection assembly 300 is a component that can detect multiple placement locations within the sample holder 900 and confirm whether a sample is placed in each placement location. The detection assembly 300 can be linked with the sampling module 20, so that the sampling module 20 moves to the placement location with a sample and performs sampling based on the detection results of the detection assembly 300.

[0057] The base 100 has a feed channel 110. The operator only needs to place the sample holder 900 at the inlet end 111 of the feed channel 110. The first drive mechanism 200 will then drive the sample holder 900 from the inlet end 111 along the feed channel 110 to the sampling position 112, thereby facilitating the sampling module 20 to sample from the sampling position 112. Because the sample holder 900 has multiple placement positions, when analyzing biological samples, not every placement position has a sample; in many cases, only some placement positions have samples. In the prior art, the sampling module 20 samples multiple placement positions sequentially. When the sampling module 20 moves to a placement position without a sample, an idle movement occurs, wasting time and resulting in low sampling efficiency. The loading device 10 provided in this embodiment is configured with a detection component 300 to detect whether a placement position has a sample, thereby determining which placement positions have samples and which placement positions do not have samples, so that the sampling module 20 can accurately move to the placement position with the sample when sampling, without any empty movement, thereby avoiding the waste of time caused by the empty movement of the sampling module 20, improving the sampling efficiency of the sampling module 20, and improving the efficiency of analyzing biological samples.

[0058] Please refer to Figure 1 In some embodiments, the base 100 includes a bottom wall 101 for supporting the sample holder 900 and a side wall 102 connected to the bottom wall 101. The bottom wall 101 and the side wall 102 enclose a feed channel 110. One end of the feed channel 110 is an inlet end 111, which is used to place the sample holder 900 before sampling by the sampling module 20, or in other words, the sample holder 900 to be sampled. The other end of the feed channel 110 is connected to a position to be sampled 112, so that the sample holder 900 placed at the inlet end 111 can be driven along the feed channel 110 to the position to be sampled 112 under the action of the first driving mechanism 200, and sampled by the sampling module 20 at the position to be sampled 112. Of course, in other embodiments, the position to be sampled 112 can also be located within the feed channel 110, which can be flexibly selected according to production needs.

[0059] In some embodiments, the feed channel 110 extends along a straight trajectory. In other embodiments, the feed channel 110 extends along an arc trajectory.

[0060] Please refer to Figure 2 , with reference Figure 3 The sample is usually placed in a sample tube, and the placement position can place the sample tube and thus realize the placement of the sample. Since there are more than one specification of sample tubes. Therefore, the sample holder 900 is also provided with multiple specifications. The number and position of the placement positions provided on the sample holder 900 of different specifications may be different. Please refer to Figure 2 , Figure 2This is a schematic structural diagram of the first sample holder 900 provided in an embodiment of the present application. The length of the first sample holder 900 matches the width of the feed channel 110. When the sample holder 900 is placed in the feed channel 110, the length direction of the sample holder 900 is parallel to the width direction of the feed channel 110. In other words, the side surfaces 910 of the sample holder 900 in the width direction are in contact with the side walls 102 of the feed channel 110, the side surfaces 910 of the sample holder 900 in the length direction are perpendicular to the side walls 102 of the feed channel 110, and the bottom wall 101 is supported on the bottom surface 920 of the sample holder 900. In this way, the sample holder 900 can be limited by the feed channel 110 during its movement in the feed channel 110, thereby preventing the sample holder 900 from escaping from the feed channel 110 or deviating from the feed channel 110 when moving in the feed channel 110.

[0061] The first type of sample holder 900 is used to place a blood collection tube 930. Since the diameter of the blood collection tube 930 is relatively small, the first type of sample holder 900 has a larger number of placement positions. Figure 2 The first sample holder 900 is provided with two rows of placement positions, each row of placement positions includes five placement positions, and the first sample holder 900 has a total of ten placement positions.

[0062] Please refer to Figure 3 , Figure 3 This is a schematic diagram of the structure of the second sample holder 900 provided in an embodiment of the present application. The shape and size of the second sample holder 900 are substantially the same as those of the first sample holder 900, except that the number of placement positions on the second sample holder 900 is different from that of the first sample holder 900. Since the second sample holder 900 also needs to match the feed channel 110, the shape and size of the second sample holder 900 are designed to be substantially the same as those of the first sample holder 900 to ensure that the second sample holder 900 can be limited by the feed channel 110 during movement within the feed channel 110, thereby preventing the second sample holder 900 from detaching from the feed channel 110 or deviating from the feed channel 110 while moving within the feed channel 110.

[0063] The second type of sample holder 900 is a sample holder 900 for placing a common sample tube 940. The common sample tube 940 can be used to place a tissue mixture, etc. Since the diameter of the common sample tube 940 is relatively large, the number of placement positions provided on the second type of sample holder 900 is relatively small. Figure 3 The second type sample holder 900 is provided with two rows of placement positions, each row of placement positions includes four placement positions, and the second type sample holder 900 has a total of eight placement positions.

[0064] It should be noted that the specifications of the sample holder 900 include but are not limited to the above two, that is, the sample holder 900 can also have more specifications to accommodate more types of sample tubes, as long as the shape and size of the sample holder 900 can be limited by the feed channel 110.

[0065] In some embodiments, to accommodate sample holders 900 of various specifications, the detection assembly 300 includes multiple rows of detection units 310 arranged along the extension direction of the feed channel 110 , and each row of detection units 310 is used to detect whether there are samples in multiple placement positions within a sample holder 900 .

[0066] The detection unit 310 is a component of the detection component 300 that realizes the detection function. The detection component 300 includes multiple detection units 310, which are arranged in rows. Each row of detection units 310 can detect whether there are samples in multiple placement positions in a sample holder 900.

[0067] By providing multiple rows of detection units 310 , it is possible to detect whether there are samples in the placement positions of sample holders 900 of various specifications, thereby improving the adaptability of the sample loading device 10 to sample tubes of different specifications.

[0068] In some embodiments, each row of detection units 310 includes a plurality of equally spaced detection units 310. The interval between two adjacent detection units 310 in a row of detection units 310 is different from the interval between two adjacent detection units 310 in another row of detection units 310 adjacent to the first row of detection units 310.

[0069] “Each row of detection units 310 includes a plurality of detection units 310 arranged at equal intervals” may be understood as the intervals between every two adjacent detection units 310 in each row of detection units 310 being the same.

[0070] “The interval between two adjacent detection units 310 in a row of detection units 310 is different from the interval between two adjacent detection units 310 in another row of detection units 310 adjacent to the one row of detection units 310” can also be understood as the positions of the detection units 310 in the two adjacent rows of detection units 310 along the extension direction of the feed channel 110 are staggered.

[0071] The distance between two adjacent placement positions of sample holders 900 of different specifications is generally different. By making the interval between two adjacent detection units 310 in one row of detection units 310 and the interval between two adjacent detection units 310 in another row of detection units 310 adjacent to the first row of detection units 310 different, it is possible to adapt to sample holders 900 of different specifications, so as to detect whether there are samples in the placement positions of sample holders 900 of various specifications, thereby improving the adaptability of the sample loading device 10 to sample tubes of different specifications.

[0072] In this embodiment, the row of detection units 310 near the inlet end 111 is used to detect the first type of sample holder 900. The distance between two adjacent detection units 310 in the row of detection units 310 near the inlet end 111 matches the distance between two adjacent placement positions in a row of placement positions in the first type of sample holder 900. The row of detection units 310 away from the inlet end 111 is used to detect the second type of sample holder 900. The distance between two adjacent detection units 310 in the row of detection units 310 away from the inlet end 111 matches the distance between two adjacent placement positions in a row of placement positions in the second type of sample holder 900. Because the distance between two adjacent placement positions in a row of placement positions in the first type of sample holder 900 and the distance between two adjacent placement positions in a row of placement positions in the second type of sample holder 900 are different, the detection units 310 in the row of detection units 310 near the inlet end 111 and the detection units 310 in the row of detection units 310 away from the inlet end 111 are staggered along the extension direction of the feed channel 110.

[0073] In some embodiments, the detection unit 310 is a photoelectric sensor, and the placement position is provided with a detection hole that can transmit the light signal emitted by the photoelectric sensor. The photoelectric sensor can emit a light signal into the detection hole. When a sample is placed at the placement position, the sample blocks the light signal, causing the photoelectric sensor to generate a first signal that the sample is present. When the sample is not placed at the placement position, the light signal is not blocked, causing the photoelectric sensor to generate a second signal that the sample is not present.

[0074] In other embodiments, the detection unit 310 includes a camera and an image processing module. The camera is electrically connected to the image processing module. The camera is used to obtain an image of the sample holder 900. The image processing module receives the image obtained by the camera and processes the image to determine whether there is a sample at each placement position on the sample holder 900.

[0075] Please refer to Figures 1 to 5 In some embodiments, the first driving mechanism 200 includes a hook 230, a movable member 220, and a driving unit 210. The hook 230 is disposed on the movable member 220, which is movably disposed on the side wall 102. The driving unit 210 is connected to the movable member 220. The hook 230 is used to avoid the sample holder 900 when the driving unit 210 drives the movable member 220 to move in the reverse direction along the extension direction of the feed channel 110. The hook 230 is also used to hook onto the side surface 910 of the sample holder 900 when the driving unit 210 drives the movable member 220 to move in the forward direction along the extension direction of the feed channel 110, so as to drive the sample holder 900 from the inlet end 111 along the feed channel 110 to the sampling position 112.

[0076] If the movable member 220 is positioned on the bottom wall 101, a groove for accommodating the movable member 220 must be provided on the bottom wall 101. If a foreign object falls into the groove or becomes lodged in the drive unit 210, such as a foreign object becoming lodged in a gear or pulley, the sample loading device 10 may malfunction and become inoperable. By positioning the movable member 220 on the side wall 102, the risk of foreign objects entering the side wall 102 and causing malfunction of the first drive mechanism 200 is reduced, as the side wall 102 is less likely to be intruded by foreign objects than the bottom wall 101. Furthermore, the hook 230 can hook onto the side surface 910 of the sample holder 900 when the drive unit 210 drives the movable member 220 to move in the forward direction of the feed channel 110, thereby driving the sample holder 900 from the inlet end 111 along the feed channel 110 to the sampling position 112, thereby transferring the sample holder 900. The hook 230 can also avoid the sample holder 900 when the driving unit 210 drives the movable member 220 to move in the opposite direction along the extension direction of the feed channel 110. In this way, when the hook 230 drives a sample holder 900 from the inlet end 111 to the sampling position 112, it can immediately retract to the inlet end 111 to transfer the next sample holder 900 without being blocked by the next sample holder 900 during the retraction process. This reduces the time it takes for the first driving mechanism 200 to drive the sample holder 900 from the inlet end 111 to the sampling position, improves the sample loading efficiency of the sample loading device 10, and thus improves the analysis efficiency of the biological sample.

[0077] In some embodiments, the drive unit 210 includes a first motor 211 and a first screw rod 212. The first motor 211 is installed at the bottom of the base 100, and the output end of the first motor 211 is connected to the first screw rod 212. The first screw rod 212 is rotatably connected to the bottom of the base 100. The movable part 220 is threadedly connected to the first screw rod 212. The bottom of the base 100 is also provided with a first slide rail 240. The first slide rail 240 extends along the extension direction of the feed channel 110, and the movable part 220 slides with the first slide rail 240. When the first motor 211 is actuated, it drives the first screw rod 212 to rotate. Since the movable part 220 slides with the first slide rail 240, the movable part 220 cannot rotate and can only move along the length direction of the first slide rail 240 under the action of the first screw rod 212, that is, the movable part 220 is moved along the extension direction of the feed channel 110.

[0078] In other embodiments, the driving unit 210 includes linear driving components such as a linear electric cylinder, a linear pneumatic cylinder, and a linear oil cylinder to directly drive the movable component 220 to move along the extension direction of the feed channel 110 .

[0079] Optionally, the movable member 220 includes a connecting portion 221 and two extending portions 222. The two extending portions 222 are arranged opposite each other along the width of the feed channel 110, and the connecting portion 221 connects the two extending portions 222. The connecting portion 221 is threadedly connected to the first screw rod 212 and slidably engages with the first slide rail 240. The end of the extending portion 222, remote from the connecting portion 221, is configured to connect to a hook 230. Each of the two extending portions 222 is provided with a hook 230. Thus, there are two hooks 230 along the width of the feed channel 110, which can simultaneously drive the sample holder 900 to move.

[0080] In some embodiments, the hook 230 has a first position and a second position. The hook 230 is configured to clear the sample support 900 when in the first position and to hook onto the side 910 of the sample support 900 when in the second position. The first drive mechanism 200 also includes a reset member 250 connected to the hook 230 and the movable member 220. The reset member 250 is configured to reset the hook 230 from the first position to the second position. When the drive unit 210 drives the movable member 220 to move in the opposite direction along the feed channel 110, the hook 230 switches from the second position to the first position. The reset member 250 accumulates an elastic force, which is used to reset the hook 230 from the first position to the second position after the hook 230 clears the sample support 900. This allows the hook 230 to hook onto the side 910 of the sample support 900 when the drive unit 210 drives the movable member 220 to move in the forward direction along the feed channel 110.

[0081] Please refer to Figure 6 In some embodiments, the extension portion 222 has a receiving cavity, the hook 230 is rotatably connected to the extension portion 222, and the reset member 250 is a torsion spring that acts on the hook 230 and the inner wall of the extension portion 222. When the hook 230 abuts the sample support 900, the hook 230 rotates to a first position under the action of the sample support 900, so that the hook 230 is received in the receiving cavity and clear of the sample support 900. After the hook 230 has cleared the sample support 900, the hook 230 rotates to a second position under the action of the reset member 250, so that the hook 230 at least partially extends out of the receiving cavity, allowing the hook 230 to be hooked to the side 910 of the sample support 900.

[0082] In other embodiments, the extension portion 222 has a receiving cavity, and the hook 230 is movably connected to the extension portion 222. The movement direction of the hook 230 forms an acute angle with the extension direction of the feed channel 110. The reset member 250 is a tension spring or a compression spring, with one end of the reset member 250 connected to the hook 230 and the other end of the reset member 250 connected to the inner wall of the extension portion 222. When the hook 230 abuts against the sample holder 900, the hook 230 moves to a first position under the action of the sample holder 900, so that the hook 230 retracts into the receiving cavity and avoids the sample holder 900. After the hook 230 bypasses the sample holder 900, the hook 230 moves to a second position under the action of the reset member 250, so that the hook 230 at least partially extends out of the receiving cavity, so that the hook 230 can be hooked to the side 910 of the sample holder 900.

[0083] In some embodiments, the sample loading device 10 includes a position detection member 400 mounted on the base 100. The position detection member 400 is used to detect whether the sample holder 900 has reached the sampling position 112, and the first driving mechanism 200 responds to the position detection member 400.

[0084] The first drive mechanism 200 drives the sample receptacle 900 until it triggers the in-place detection element 400, indicating that the sample receptacle 900 has reached the sampling position 112. At this point, the first drive mechanism 200 can begin preparing to move the next sample receptacle 900. The in-place detection element 400 improves the accuracy of the first drive mechanism 200 in driving the sample receptacle 900 to the sampling position 112, ensuring the accurate and reliable relative position of the sample receptacle 900 and the sampling module 20. This improves the sampling efficiency of the sampling module 20 and enhances the efficiency of biological sample analysis.

[0085] In some embodiments, the in-position detection member 400 is a position switch mounted on the base 100 near the sampling position 112 and in the extending direction of the feed channel 110. When the first drive mechanism 200 drives the sample holder 900 along the feed channel 110 until the sample holder 900 triggers the position switch, it indicates that the sample holder 900 has reached the sampling position 112. At this point, the first drive mechanism 200, in response to the position switch, begins preparing to move the next sample holder 900.

[0086] In other embodiments, the in-position detection member 400 is a distance sensor mounted on the base 100 and configured to detect the distance between the sensor and the sample holder 900 closest to the distance sensor. When the first drive mechanism 200 drives the sample holder 900 along the feed channel 110 until the distance measured by the distance sensor equals a preset value, the sample holder 900 has reached the sampling position 112. At this point, the first drive mechanism 200, in response to the distance sensor, begins preparing to move the next sample holder 900.

[0087] Please refer to Figure 7 In some embodiments, the sample loading device 10 includes a controller 320, which is electrically connected to the in-place detection member 400 and the first drive mechanism 200. The controller 320 is a master device that controls the target action according to a predetermined program. The controller 320 can be a CPU (central processing unit), an ECU (electronic control unit), a PLC (programmable logic controller), or the like.

[0088] When the in-position detection member 400 detects that the sample holder 900 has reached the sampling position 112 , the in-position detection member 400 sends an in-position signal to the controller 320 . The controller 320 receives the in-position signal and controls the first driving mechanism 200 to prepare to move the next sample holder 900 .

[0089] In some embodiments, the detection component 300 is electrically connected to the controller 320, which is configured to be electrically connected to the sampling module 20. The detection component 300 can detect whether a sample is present at a placement location and send a first signal indicating that a sample is present at the placement location to the controller 320. The controller 320 receives the first signal and, based on the first signal, controls the sampling module 20 to move toward the placement location with the sample and take a sample.

[0090] In some embodiments, the sample loading device 10 includes a first alarm 330 , which responds to the detection result of the detection component 300 and sounds an alarm when the detection component 300 detects that there is no sample in at least one placement position.

[0091] The first alarm 330 is a product that uses sound, light, air pressure, or other means to remind or warn operators to take certain actions to prevent or mitigate the consequences of an event. In some embodiments, the first alarm 330 is a display that displays a warning message when triggered. In other embodiments, the first alarm 330 may be a buzzer. In still other embodiments, the first alarm 330 includes a multi-colored LED light that emits different colors to sound the alarm.

[0092] By setting the first alarm 330, the first alarm 330 can alarm when the detection component 300 detects that there is no sample in at least one placement position, so as to warn the operator whether there is a sample missing. The operator can only perform the sample loading operation after confirming that there is no error.

[0093] In some embodiments, the detection component 300 is electrically connected to the controller 320, and the controller 320 is electrically connected to the first alarm 330. The detection component 300 can detect whether there is a sample at the placement position and send a second signal to the controller 320 indicating that there is no sample at the placement position. The controller 320 receives the second signal and controls the first alarm 330 to sound an alarm based on the second signal.

[0094] In some embodiments, the base 100 further has a discharge channel 130 and a transfer channel 120. The discharge channel 130 is used for moving the sample holder 900 after sampling by the sampling module 20, and the discharge channel 130 has an outlet end 131. The transfer channel 120 connects the feed channel 110 and the discharge channel 130. The loading device 10 further includes a second driving mechanism 500 and a third driving mechanism 600. The second driving mechanism 500 is connected to the base 100, and the second driving mechanism 500 is used to transfer the sample holder 900 after sampling by the sampling module 20 from the sampling position 112 along the transfer channel 120 to the discharge channel 130. The third driving mechanism 600 is connected to the base 100, and the third driving mechanism 600 is used to drive the sample holder 900 transferred by the second driving mechanism 500 along the discharge channel 130 to the outlet end 131.

[0095] The discharge channel 130 is a channel on the base 100 used to guide the sample holder 900 after sampling by the sampling module 20, thereby directing the sample holder 900 out of the outlet port 131. The transfer channel 120 is a channel on the base 100 used to guide the sample holder 900 after sampling by the sampling module 20, thereby transferring the sample holder 900 from the sampling position 112 to the discharge channel 130. The second drive mechanism 500 is a mechanism capable of moving the sample holder 900 after sampling by the sampling module 20 along the transfer channel 120. The third drive mechanism 600 is a mechanism capable of moving the sample holder 900 after sampling by the sampling module 20 along the discharge channel 130.

[0096] The second drive mechanism 500 facilitates the transfer of the sample holder 900, after sampling by the sampling module 20, from the sampling position 112 along the transfer channel 120 to the discharge channel 130. The third drive mechanism 600 facilitates the drive of the sample holder 900, after being transferred by the second drive mechanism 500, along the discharge channel 130 to the outlet port 131. An operator can remove the sample holder 900 from the sampling module 20 at the outlet port 131, ensuring that the sample collection and loading processes do not interfere with each other. This accelerates the sample loading efficiency of the sample loading device 10 and improves the efficiency of biological sample analysis.

[0097] In some embodiments, the feed channel 110 and the discharge channel 130 are arranged side by side, and the extension direction of the transfer channel 120 is perpendicular to the extension direction of the feed channel 110 and the discharge channel 130. Figure 1 or Figure 4As shown, the feed channel 110, the transfer channel 120, and the discharge channel 130 form a U-shaped channel. By arranging the feed channel 110 and the discharge channel 130 side by side and extending the transfer channel 120 perpendicular to the extending directions of the feed channel 110 and the discharge channel 130, the length of the sample loading device 10 can be reduced, so that the sample loading device 10 can adapt to the size of the analysis chamber.

[0098] In another embodiment, the feeding channel 110, the transfer channel 120 and the discharging channel 130 are arranged in sequence along a straight line. In this way, the sample loading device 10 is longer in length but smaller in width, and can be adapted to some special spaces, such as a long corridor.

[0099] In some embodiments, the second drive mechanism 500 includes a second motor 510, a second screw rod 520, a sliding seat 530, and a hook 230. The second motor 510 is mounted on the base 100, and the output end of the second motor 510 is connected to the second screw rod 520. The second screw rod 520 is rotatably connected to the base 100. The sliding seat 530 is threadedly connected to the second screw rod 520. The base 100 is also provided with a second slide rail 550, which extends along the extension direction of the transfer channel 120. The sliding seat 530 is slidably engaged with the second slide rail 550, and the hook 230 is connected to the sliding seat 530. When the second motor 510 is in operation, it drives the second screw rod 520 to rotate. Since the sliding seat 530 slides with the second slide rail 550, the sliding seat 530 cannot rotate and can only move along the length direction of the second slide rail 550 under the action of the second screw rod 520, that is, the sliding seat 530 is moved along the extension direction of the transfer channel 120, and the sample holder 900 after sampling by the sampling module 20 is transferred from the sampling position 112 along the transfer channel 120 to the discharge channel 130.

[0100] In other embodiments, the second driving mechanism 500 includes a linear driving member such as a linear electric cylinder, a linear pneumatic cylinder, and a linear oil cylinder to directly drive the sliding seat 530 to move along the extension direction of the transfer channel 120 .

[0101] The structure of the third driving mechanism 600 may refer to the first driving mechanism 200 or the second driving mechanism 500 described above, and will not be described in detail here.

[0102] In some embodiments, the sample loading device 10 further includes a discharge drawer 700, which is movably disposed at the outlet end 131 and is used to receive the sample holders 900 driven by the third drive mechanism 600. The provision of the discharge drawer 700 allows for temporary storage of the sample holders 900 after sampling by the sampling module 20. When the discharge drawer 700 is filled with sample holders 900 after sampling by the sampling module 20, the sample holders 900 in the discharge drawer 700 are then cleaned out. This helps reduce the frequency of cleaning the sample holders 900 and reduces the workload of operators.

[0103] In some embodiments, the loading device 10 includes a full material detector 710 and a second alarm 340. The full material detector 710 is mounted on the discharge drawer 700 and is used to detect whether the discharge drawer 700 is full. The second alarm 340 responds to the detection result of the full material detector 710 and alarms when the discharge drawer 700 is full.

[0104] In some embodiments, the full-fill detection member 710 is a position switch and is mounted on the inner wall of the discharge drawer 700 near the drawer handle. The third drive mechanism 600 drives the sample holders 900, after sampling by the sampling module 20, along the discharge channel 130 to the discharge drawer 700. The sample holders 900, after sampling by the sampling module 20, accumulate in the discharge drawer 700, causing the first sample holder 900 to be gradually squeezed closer to the full-fill detection member 710, ultimately triggering the full-fill detection member 710, indicating that the discharge drawer 700 is full. At this point, the second alarm 340 sounds in response to the full-fill detection member 710.

[0105] In other embodiments, the full material detection member 710 is a distance sensor. The full material detection member 710 is installed on the inner wall surface of the discharge drawer 700 near the drawer handle, and the distance sensor is used to obtain the distance between it and the sample holder 900 closest to the distance sensor. The third drive mechanism 600 drives the sample holder 900 sampled by the sampling module 20 to move along the discharge channel 130 to the discharge drawer 700. The sample holder 900 sampled by the sampling module 20 accumulates in the discharge drawer 700, so that the sample holder 900 that enters first is gradually squeezed close to the full material detection member 710 until the distance measured by the full material detection member 710 is equal to the preset value, that is, the full material detection member 710 is triggered, indicating that the discharge drawer 700 is full. At this time, the second alarm 340 sounds an alarm in response to the full material detection member 710.

[0106] By providing a full material detection member 710 , it is convenient to detect whether the discharge drawer 700 is full of material. The second alarm 340 can alarm when the discharge drawer 700 is full of material, alerting the operator to clean the discharge drawer 700 .

[0107] Please refer to Figure 7In some embodiments, the full-material detection element 710 is electrically connected to the controller 320, and the controller 320 is electrically connected to the second alarm 340. When the full-material detection element 710 detects that the discharge drawer 700 is full, it sends a full-material signal to the controller 320. The controller 320 receives the full-material signal and controls the second alarm 340 to sound an alarm.

[0108] In some embodiments, the loading device 10 further includes a feed drawer 800, which is movably disposed at the inlet end 111. The feed drawer 800 is used to place the sample holder 900 before sampling by the sampling module 20. The first driving mechanism 200 is used to drive the sample holder 900 in the feed drawer 800 along the feed channel 110 to the position to be sampled 112. By providing the feed drawer 800, the sample holders 900 before sampling by multiple sampling modules 20 can be placed in the feed drawer 800 at the same time, and the first driving mechanism 200 will automatically move these sample holders 900 to the position to be sampled 112 in sequence. In this way, the frequency of the operator placing the sample holder 900 before sampling by the sampling module 20 can be reduced, thereby reducing the labor intensity of the operator.

[0109] The sample loading device 10 provided in the embodiment of the present application works as follows:

[0110] First, the operator pulls out the feed drawer 800, places the sample holder 900 (or the sample holder 900 to be sampled) before sampling by the sampling module 20 into the feed drawer 800, and then pushes the feed drawer 800 back. The drive unit 210 then activates, driving the hook 230 to move the sample holder 900 from the feed drawer 800 along the feed channel 110 to the sampling position 112. As the sample holder 900 moves from the feed drawer 800 along the feed channel 110 to the sampling position 112, it passes through the detection assembly 300, which detects whether multiple placement positions within the sample holder 900 contain a sample. If at least one of the multiple placement positions does not contain a sample, the first alarm 330 sounds an alarm. After the operator confirms that everything is correct, the operation continues.

[0111] The first drive mechanism 200 drives the sample holder 900 along the feed channel 110 until the in-position detection member 400 is triggered, indicating that the sample holder 900 has reached the sampling position 112. The sampling module 20 extracts a sample from the sample placement position based on the detection results of the detection assembly 300. The first drive mechanism 200 then prepares to move the next sample holder 900.

[0112] After the sampling module 20 completes sampling, the second drive mechanism 500 is activated to move the sample holder 900 sampled by the sampling module 20 from the sampling position 112 to the discharge channel 130. After the sample holder 900 sampled by the sampling module 20 leaves the sampling position 112, the first drive mechanism 200 moves the next sample holder 900 to the sampling position 112.

[0113] After the sample holder 900, sampled by the sampling module 20, enters the discharge channel 130 and is driven by the third drive mechanism 600 to the discharge drawer 700 for temporary storage. When the full-fill detection element 710 is triggered, the second alarm 340 sounds, alerting the operator to clean the discharge drawer 700. Alternatively, after completing the sample loading process, the operator can clean the discharge drawer 700 themselves.

[0114] Please refer to Figure 8 This embodiment also provides a sampling device 30, which includes the above-mentioned sample loading device 10 and a sampling module 20. The sampling module 20 is electrically connected to the detection component 300, and the sampling module 20 is used to respond to the detection results of the detection component 300.

[0115] Please refer to Figure 9 This embodiment further provides a sampling method. The sampling method is based on the above-mentioned sampling device 30 and includes:

[0116] Step S1: placing the sample holder 900 of the sampling module 20 before sampling into the inlet end 111;

[0117] Step S2: driving the sample holder 900 from the inlet end 111 along the feeding channel 110 to the sampling position 112 by the first driving mechanism 200;

[0118] Step S3: During the process of driving the sample holder 900 from the inlet end 111 along the feeding channel 110 to the sampling position 112 by the first driving mechanism 200 , the detection component 300 detects whether there is a sample at the placement position;

[0119] Step S4 : the sampling module 20 takes a sample from the placement location having the sample in response to the detection result of the detection component 300 .

[0120] The foregoing description is merely a preferred embodiment of the present application and is not intended to limit the present application. Persons skilled in the art will readily appreciate that various modifications and variations are possible. Any modifications, equivalent substitutions, or improvements made within the spirit and principles of the present application shall be included within the scope of protection of the present application.

Claims

1. A sample loading device, characterized in that: include: A base having a feeding channel for the sample holder to move, the feeding channel having an inlet end, and the sample holder having a plurality of placement positions for placing samples; a first driving mechanism connected to the base, the first driving mechanism being used to drive the sample holder from the inlet end along the feed channel to a sampling position so that the sampling module can take the sample out of the placement position; a detection component connected to the base, the detection component being used to detect whether the placement position has a sample, the sampling module responding to a detection result of the detection component; The base includes a bottom wall for supporting the sample holder and a side wall connected to the bottom wall, wherein the bottom wall and the side wall enclose the feeding channel; The detection assembly is arranged on the bottom wall, and the first drive mechanism is arranged on the side wall. The detection assembly includes multiple rows of detection units arranged along the extension direction of the feed channel, each row of the detection units includes multiple detection units arranged at equal intervals, and the interval between two adjacent detection units in a row of detection units is different from the interval between two adjacent detection units in another row of detection units adjacent to the first row of detection units. Each row of detection units is used to detect whether there are samples in multiple placement positions in a sample holder.

2. The sample loading device according to claim 1, characterized in that: The detection unit is a photoelectric sensor, and the placement position is correspondingly provided with a detection hole that can transmit the light signal emitted by the photoelectric sensor.

3. The sample loading device according to claim 1, characterized in that: The sample loading device includes a first alarm, which responds to the detection result of the detection component and alarms when the detection component detects that there is no sample in at least one of the placement positions.

4. The sample loading device according to claim 1, characterized in that: The first driving mechanism includes a hook, a movable part and a driving unit, the hook is provided on the movable part, the movable part is movably provided on the side wall, the driving unit is connected to the movable part, the hook is used to avoid the sample holder when the driving unit drives the movable part to move in the reverse direction along the extension direction of the feed channel, and the hook is also used to hook on the side of the sample holder when the driving unit drives the movable part to move in the forward direction along the extension direction of the feed channel, so as to drive the sample holder from the inlet end along the feed channel to the position to be sampled.

5. The sample loading device according to claim 4, characterized in that: The hook has a first position and a second position, the hook is used to avoid the sample holder when it is in the first position, and is also used to hook on the side of the sample holder when it is in the second position; The first driving mechanism further includes a reset member connected to the hook and the movable member, and the reset member is used to reset the hook from the first position to the second position.

6. The sample loading device according to claim 1, characterized in that: The sample loading device includes an in-place detection member installed on the base, and the in-place detection member is used to detect whether the sample holder reaches the position to be sampled. The first driving mechanism responds to the in-place detection member.

7. The sample loading device according to claim 1, characterized in that: The base also has: A discharge channel, used for moving the sample holder after the sampling module has taken samples, and the discharge channel has an outlet end; a transfer channel, connecting the feed channel and the discharge channel; The sample loading device also includes: a second driving mechanism connected to the base, the second driving mechanism being used to transfer the sample holder after sampling by the sampling module from the to-be-sampled position along the transfer channel to the discharge channel; The third driving mechanism is connected to the base, and is used to drive the sample holder transferred by the second driving mechanism along the discharge channel to the outlet end.

8. The sample loading device according to claim 7, characterized in that: The feed channel and the discharge channel are arranged side by side, and the extension direction of the transfer channel is perpendicular to the extension directions of the feed channel and the discharge channel.

9. The sample loading device according to claim 7, characterized in that: The sample loading device also includes: A discharge drawer is movably disposed at the outlet end, and is used to accommodate the sample holder driven by the third driving mechanism.

10. The sample loading device according to claim 9, characterized in that: The sample loading device comprises: A full material detection component is installed on the discharge drawer, and the full material detection component is used to detect whether the discharge drawer is full; The second alarm is responsive to the detection result of the full material detection element to sound an alarm when the discharge drawer is full.

11. The sample loading device according to claim 1, characterized in that: The sample loading device also includes: A feed drawer is movably arranged at the inlet end, and is used to place the sample holder before the sampling module takes samples. The first driving mechanism is used to drive the sample holder in the feed drawer along the feed channel to the position to be sampled.

12. A sampling device, characterized in that: include: The sample loading device according to any one of claims 1 to 11; The sampling module is electrically connected to the detection component, and is used to respond to the detection result of the detection component.

13. A sampling method, characterized in that: Based on the sampling device according to claim 12, the sampling method comprises: Place the sample holder before sampling by the sampling module into the inlet end; driving the sample holder from the inlet end along the feed channel to the position to be sampled by the first driving mechanism; In the process of driving the sample holder from the inlet end along the feed channel to the position to be sampled by the first driving mechanism, detecting whether there is a sample at the placement position by the detection component; The sampling module takes a sample from the placement position having the sample in response to a detection result of the detection component.

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