Anti-interference detection method and sample analyzer

Abstract

An anti-interference detection method and a sample analyzer are used to achieve anti-interference measurement of a sample without sample pre-testing. The method comprises: adding a reagent for executing a test item to the sample and mixing it to obtain a sample mixture (401); irradiating the sample mixture with multi-wavelength light, the multi-wavelength light including a main wavelength and a sub-wavelength (402) corresponding to the measurement item of the sample; obtaining an initial light flux γ1 of the main wavelength, an initial light flux γ2 of the sub-wavelength, and a light flux threshold α corresponding to the measurement item (403); and applying an anti-interference detection method (404) to the sample based on a comparison result of γ1, γ2, and α.

Description

Technical Field

[0001] The present invention relates to the technical field of sample detection, and in particular to an anti-interference detection method and a sample analyzer. Background Art

[0002] When optically detecting coagulation, the solution in the reaction cup is usually illuminated with collimated light and the scattered or transmitted light is analyzed to obtain the absorbance of the solution, thereby obtaining the coagulation time or the concentration of the analyte.

[0003] Generally speaking, normal plasma is light yellow, transparent and has very low absorbance. However, jaundice, hemolysis and chyle samples with obvious absorption peaks, which may seriously affect the transmittance, may affect the measurement and pose a challenge to the credibility of the optical method.

[0004] Based on this, the prior art proposes an anti-interference method based on sample pre-detection. This method requires pre-detection of interferers on the sample and determines whether anti-interference measurement needs to be performed based on the detection result.

[0005] Commonly used anti-interference methods have the following problems:

[0006] 1. Blood sample waste: blood samples need to be wasted for interfering substance detection;

[0007] 2. Waste of reaction cups or increase of colorimetric cell structure: Usually, the split cup method or colorimetric cell method is used for interference detection. The former wastes reaction cups and increases detection costs; the latter increases the complexity of the instrument;

[0008] 3. Added process: The interference measurement process was added, which resulted in a decrease in the speed of project testing for samples.

[0009] Therefore, how to achieve anti-interference measurement of samples without sample pre-inspection is an urgent problem to be solved. Summary of the Invention

[0010] The embodiments of the present invention provide an anti-interference detection method and a sample analyzer, which are used to implement anti-interference processing on samples without sample pre-testing.

[0011] A first aspect of an embodiment of the present invention provides an anti-interference detection method, including:

[0012] Add the reagent for performing the test item to the sample and mix well to obtain a sample mixture;

[0013] Irradiating the sample mixture with multi-wavelength light, wherein the multi-wavelength light includes a main wavelength and a sub-wavelength corresponding to a measurement item of the sample;

[0014] Obtaining an initial luminous flux γ1 of the main wavelength, an initial luminous flux γ2 of the sub-wavelength, and a luminous flux threshold α corresponding to the measurement item;

[0015] According to the comparison results of γ1, γ2 and α, an anti-interference detection method is applied to the sample.

[0016] Preferably, the anti-interference detection method is applied to the sample according to the comparison results of γ1, γ2 and α, including:

[0017] If γ1≥α, the sample is detected using the dominant wavelength;

[0018] If γ1<α≤γ2, the sub-wavelength is used to detect the sample.

[0019] Preferably, the method of applying an anti-interference detection method to the sample based on the comparison results of γ1, γ2 and α further includes:

[0020] If γ2<α, then after increasing the intensity of the light source corresponding to the dominant wavelength and / or increasing the gain of the sensor circuit for collecting the light flux, obtaining the initial light flux γ3 of the sample mixture under the illumination of the dominant wavelength;

[0021] If γ3≥α, anti-interference detection is performed on the sample using the main wavelength.

[0022] Preferably, the method of applying an anti-interference detection method to the sample based on the comparison results of γ1, γ2 and α further includes:

[0023] If γ2<α, then after increasing the intensity of the light source corresponding to the sub-wavelength and / or increasing the gain of the sensor circuit for collecting the light flux, obtaining the initial light flux γ4 of the sample mixture under the illumination of the sub-wavelength;

[0024] If γ4≥α, anti-interference detection is performed on the sample using the secondary wavelength.

[0025] Preferably, the method further comprises:

[0026] If γ3<α, dilute the sample mixture;

[0027] Obtaining an initial light flux γ5 of the diluted sample mixture under irradiation with the main wavelength;

[0028] If γ5≥α, anti-interference detection is performed on the sample using the main wavelength.

[0029] Preferably, the method further comprises:

[0030] If γ4<α, dilute the sample mixture;

[0031] Obtaining an initial light flux γ6 of the diluted sample mixture under the irradiation of the sub-wavelength;

[0032] If γ6≥α, anti-interference detection is performed on the sample using the secondary wavelength.

[0033] Preferably, the method further comprises:

[0034] When a single wavelength is used to measure the sample, the initial light flux of the sample mixture under the illumination of the single wavelength is obtained.

[0035] like Then, the single wavelength is used to perform item detection on the sample.

[0036] Preferably, the method further comprises:

[0037] like After increasing the intensity of the light source corresponding to the single wavelength and / or increasing the gain of the sensor circuit for collecting the light flux, the initial light flux of the sample mixture under the illumination of the single wavelength is obtained.

[0038] like Then, the single wavelength is used to perform anti-interference detection on the sample.

[0039] Preferably, the method further comprises:

[0040] like Then diluting the sample mixture;

[0041] Obtain the initial luminous flux of the diluted sample mixture under the irradiation of the single wavelength

[0042] like Then, the single wavelength is used to perform anti-interference detection on the sample.

[0043] A second aspect of an embodiment of the present invention provides a sample analyzer, characterized by comprising:

[0044] Measuring container, used to hold the mixed solution of sample and measuring reagent for executing the project;

[0045] an optical device for providing multi-wavelength light and irradiating the mixed liquid with the multi-wavelength light, wherein the multi-wavelength light includes a main wavelength and a sub-wavelength corresponding to the measurement item of the sample;

[0046] A light flux collection device, used to obtain initial light fluxes γ1 and γ2 of the sample mixture under the irradiation of the main wavelength and the sub-wavelength respectively;

[0047] Processor for:

[0048] Obtaining a luminous flux threshold α corresponding to the measurement item;

[0049] According to the comparison results of γ1, γ2 and α, an anti-interference detection method is applied to the sample.

[0050] Preferably, the processor is specifically configured to:

[0051] If γ1≥α, the sample is detected using the dominant wavelength;

[0052] If γ1<α≤γ2, the sub-wavelength is used to detect the sample.

[0053] Preferably, the processor is further configured to:

[0054] If γ1<α, then after increasing the intensity of the light source corresponding to the dominant wavelength and / or increasing the gain of the sensor circuit for collecting the light flux, obtaining the initial light flux γ3 of the sample mixture under the illumination of the dominant wavelength;

[0055] If γ3≥α, anti-interference detection is performed on the sample using the main wavelength.

[0056] Preferably, the processor is further configured to:

[0057] If γ2<α, then after increasing the intensity of the light source corresponding to the sub-wavelength and / or increasing the gain of the sensor circuit for collecting the light flux, obtaining the initial light flux γ4 of the sample mixture under the illumination of the sub-wavelength;

[0058] If γ4≥α, anti-interference detection is performed on the sample using the secondary wavelength.

[0059] Preferably, the processor is further configured to:

[0060] If γ3<α, dilute the sample mixture;

[0061] Obtaining an initial light flux γ5 of the diluted sample mixture under irradiation with the main wavelength;

[0062] If γ5≥α, anti-interference detection is performed on the sample using the main wavelength.

[0063] Preferably, the processor is further configured to:

[0064] If γ4<α, dilute the sample mixture;

[0065] Obtaining an initial light flux γ6 of the diluted sample mixture under the irradiation of the sub-wavelength;

[0066] If γ6≥α, anti-interference detection is performed on the sample using the secondary wavelength.

[0067] Preferably, the processor is further configured to:

[0068] When a single wavelength is used to measure the sample, the initial light flux of the sample mixture under the illumination of the single wavelength is obtained.

[0069] like Then, the single wavelength is used to perform item detection on the sample.

[0070] Preferably, the processor is further configured to:

[0071] like After increasing the intensity of the light source corresponding to the single wavelength and / or increasing the gain of the sensor circuit for collecting the light flux, the initial light flux of the sample mixture under the illumination of the single wavelength is obtained.

[0072] like Then, the single wavelength is used to perform anti-interference detection on the sample.

[0073] Preferably, the processor is further configured to:

[0074] like Then diluting the sample mixture;

[0075] Obtain the initial luminous flux of the diluted sample mixture under the irradiation of the single wavelength

[0076] like Then, the single wavelength is used to perform anti-interference detection on the sample.

[0077] Preferably, the sample analyzer is a coagulation analyzer.

[0078] An embodiment of the present invention further provides a computer storage medium on which a computer program is stored. When the computer program is executed by a processor, it is used to implement the anti-interference detection method provided by the first aspect of the embodiment of the present invention.

[0079] In the technical solution provided by the embodiment of the present invention, a reagent for performing item detection is added to a sample and mixed to obtain a sample mixture; the sample mixture is irradiated with multi-wavelength light, wherein the multi-wavelength light includes a main wavelength and a sub-wavelength corresponding to the measurement item of the sample; an initial light flux γ1 of the main wavelength, an initial light flux γ2 of the sub-wavelength, and a light flux threshold α corresponding to the measurement item are obtained; and based on the comparison result of γ1, γ2 and α, an anti-interference detection method is applied to the sample, thereby achieving anti-interference measurement of the sample without pre-detection of sample interferents. BRIEF DESCRIPTION OF THE DRAWINGS

[0080] Figure 1 A schematic structural diagram of a sample analyzer according to an embodiment of the present invention;

[0081] Figure 2 is another structural schematic diagram of a sample analyzer according to an embodiment of the present invention;

[0082] Figure 3 is another structural schematic diagram of a sample analyzer according to an embodiment of the present invention;

[0083] Figure 4 A schematic diagram of an embodiment of an anti-interference detection method according to an embodiment of the present invention;

[0084] Figure 5 In the embodiment of the present invention Figure 4 Refinement of step 404 of the embodiment:

[0085] Figure 6 A schematic diagram of another embodiment of the anti-interference detection method in an embodiment of the present invention;

[0086] Figure 7 A schematic diagram of another embodiment of the anti-interference detection method in an embodiment of the present invention;

[0087] Figure 8 A schematic diagram of another embodiment of the anti-interference detection method in an embodiment of the present invention;

[0088] Figure 9 A schematic diagram of another embodiment of the anti-interference detection method in an embodiment of the present invention;

[0089] Figure 10 A schematic diagram of another embodiment of the anti-interference detection method in an embodiment of the present invention;

[0090] Figure 11 FIG. 1 is a schematic diagram of a sample analyzer according to an embodiment of the present invention. DETAILED DESCRIPTION

[0091] The following will clearly and completely describe the technical solutions in the embodiments of the present invention in conjunction with the accompanying drawings. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without making any creative efforts shall fall within the scope of protection of the present invention.

[0092] The terms "first," "second," "third," "fourth," and the like (if any) in the description and claims of the present invention and the accompanying drawings are used to distinguish similar objects and are not necessarily used to describe a particular order or precedence. It should be understood that the terms used in this manner are interchangeable where appropriate so that the embodiments described herein can be implemented in an order other than that illustrated or described herein. In addition, the terms "including" and "having," as well as any variations thereof, are intended to cover non-exclusive inclusions, e.g., a process, method, system, product, or apparatus comprising a series of steps or units is not necessarily limited to those steps or units explicitly listed, but may include other steps or units not explicitly listed or inherent to such processes, methods, products, or apparatus.

[0093] Before describing the present invention in detail, the structure of the sample analyzer is described first. Figure 1 In one embodiment, the sample analyzer may include a sample component 10, a reagent component 20, a determination component 30, a memory 40, and a processor 50; in some embodiments, please refer to Figure 2 The sample analyzer may further include a display and operation component 60, which will be described in detail below.

[0094] The sample component 10 is used to carry the sample in the test liquid and provide the sample to the measuring component 30 after aspirating the sample. Figure 3 In some embodiments, the sample component 10 may include a sample carrying component 11 and a sample dispensing mechanism 12. The sample carrying component 11 is used to carry the sample. In some examples, the sample carrying component 11 may include a sample delivery module (SDM) and a front track; in other examples, for example, Figure 3For example, the sample carrying component 11 can also be a sample tray, which includes a plurality of sample positions such as sample tubes. The sample tray can dispatch the sample to the corresponding position by rotating its tray structure, such as the position for the sample dispensing mechanism 12 to absorb the sample. The sample dispensing mechanism 12 is used to absorb the sample and discharge it into the reaction cup to be loaded. For example, the sample dispensing mechanism 12 may include a sample needle, and the sample needle performs two-dimensional or three-dimensional movement in space through a two-dimensional or three-dimensional driving mechanism, so that the sample needle can move to absorb the sample carried by the sample carrying component 11, and move to the reaction cup to be loaded, and discharge the sample into the reaction cup.

[0095] The reagent component 20 is used to carry the reagent in the test liquid, and provides the reagent to the measuring component 30 after absorbing the reagent. In some embodiments, the reagent component 20 may include a reagent carrying component 13 and a reagent dispensing mechanism 14. The reagent carrying component 13 is used to carry the reagent. In one embodiment, the reagent carrying component 13 can be a reagent disk, which is arranged in a disc-shaped structure and has a plurality of positions for carrying reagent containers. The reagent carrying component 13 can rotate and drive the reagent container it carries to rotate, and is used to rotate the reagent container to a specific position, such as a position where the reagent is absorbed by the reagent dispensing mechanism 14. The number of reagent carrying components 13 can be one or more. The reagent dispensing mechanism 14 is used to absorb the reagent and discharge it into a reaction cup to be added with the reagent. In one embodiment, the reagent dispensing mechanism 14 may include a reagent needle, which performs two-dimensional or three-dimensional movement in space through a two-dimensional or three-dimensional driving mechanism, so that the reagent needle can move to absorb the reagent carried by the reagent carrying component 13, and move to the reaction cup to be added with the reagent, and discharge the reagent into the reaction cup.

[0096] The measuring component 30 is used to perform item tests on the sample to obtain the test data of the item. In some embodiments, the measuring component 30 may include a reaction component 15 and a light measuring component 16. Specifically, in an embodiment of the present invention, the reaction component is a measuring container, wherein the measuring container is used to carry a mixed liquid prepared by the sample and the detection reagent. The light measuring component 16 is used to perform optical measurement on the mixed liquid to obtain the reaction data of the sample, such as the light measuring component 16 detects the luminous intensity of the reaction liquid to be tested, and obtains the concentration of the component to be tested in the sample by querying the calibration curve. Specifically in the present embodiment, the light measuring component 16 includes a multi-wavelength light source, a spectrometer, an optical processing device and a signal acquisition device. In some embodiments, the light measuring component 16 can also be separately arranged outside the reaction component 15.

[0097] based on Figures 1 to 3 The following describes the anti-interference detection method in the embodiment of the present invention. Figure 4 , an embodiment of the anti-interference detection method in an embodiment of the present invention includes:

[0098] 401. Add the reagent for performing the test item to the sample and mix well to obtain a sample mixture;

[0099] This is different from the existing technology which requires first measuring the interference content in the sample and then analyzing the sample detection items based on the measured interference content, which results in multiple measurement steps for the sample detection items and low detection efficiency.

[0100] The present invention proposes an anti-interference detection method, which does not require the pre-determination of the interference content in the sample, but directly performs item detection on the sample, thereby reducing the sample pre-inspection steps compared to the existing technology and improving the efficiency of sample item detection.

[0101] Specifically, before performing item detection on the sample, it is necessary to add the reagent for performing the item detection into the sample and mix it to obtain a sample mixture.

[0102] 402. Irradiate the sample mixture with multi-wavelength light, where the multi-wavelength light includes a main wavelength and a sub-wavelength corresponding to a measurement item of the sample;

[0103] When performing multi-wavelength detection item analysis on a sample (such as immunoturbidimetric detection), the detection item generally has a main wavelength and a sub-wavelength corresponding to the detection item itself. In this embodiment, after obtaining the sample mixture, multi-wavelength light including at least the main wavelength and the sub-wavelength is used to irradiate the sample mixture.

[0104] Among them, the selection of the main and sub-wavelengths of the detection project is mainly determined by the reagent requirements during the detection project. When performing the detection project on the sample, the main wavelength is required to be able to characterize the reaction process between the sample and the reagent as much as possible. On the other hand, it is also required to ensure that the signal intensity collected by the optical measurement component during the entire test process (that is, to ensure the intensity of the transmitted light) meets the requirements of the detection project.

[0105] 403. Obtain an initial luminous flux γ1 of the main wavelength, an initial luminous flux γ2 of the sub-wavelength, and a luminous flux threshold α corresponding to the measurement item;

[0106] It is easy to understand that when performing item testing on a sample, if the content of the interfering substance in the sample exceeds the interfering substance content threshold, it will cause certain interference to the item testing result of the sample, thereby reducing the accuracy of the item testing of the sample.

[0107] In order to ensure the accuracy of the sample test results, when using optical measurement components to perform project testing on the sample, it is generally required that the luminous flux that the optical measurement components can measure is greater than a certain threshold to ensure the accuracy of the sample project test results. Each measurement item of the sample corresponds to its own luminous flux threshold, and the luminous flux threshold is generally determined by experiment.

[0108] Therefore, in order to ensure the accuracy of the sample item detection results, that is, to achieve anti-interference measurement of the sample, the embodiment of the present invention needs to obtain the initial luminous flux γ1 of the main wavelength and the initial luminous flux γ2 of the sub-wavelength that match the measurement item, as well as the luminous flux threshold α corresponding to the measurement item, and execute step 404 based on the relationship between the above-mentioned luminous flux values.

[0109] 404. Based on the comparison results of γ1, γ2 and α, an anti-interference detection method is applied to the sample.

[0110] After obtaining the initial luminous flux γ1 of the main wavelength, the initial luminous flux γ2 of the secondary wavelength, and the luminous flux threshold α corresponding to the measurement item, the embodiment of the present invention adopts an anti-interference detection method for the sample based on the comparison results of γ1, γ2 and α to ensure the accuracy of the measurement results of the sample item.

[0111] As for the process of applying the anti-interference detection method to the sample according to the comparison results of γ1, γ2 and α, it will be described in detail in the following embodiments and will not be repeated here.

[0112] In the technical solution provided by the embodiment of the present invention, a reagent for performing item detection is added to a sample and mixed to obtain a sample mixture; the sample mixture is irradiated with multi-wavelength light, wherein the multi-wavelength light includes a main wavelength and a sub-wavelength corresponding to the measurement item of the sample; an initial light flux γ1 of the main wavelength, an initial light flux γ2 of the sub-wavelength, and a light flux threshold α corresponding to the measurement item are obtained; and based on the comparison result of γ1, γ2 and α, an anti-interference detection method is applied to the sample, thereby achieving anti-interference measurement of the sample without pre-detection of sample interferents.

[0113] based on Figure 4 In the embodiment described above, step 404 is described in detail below. Figure 5 , Figure 5 for Figure 4 The detailed steps of step 404 in the embodiment are as follows:

[0114] 501. If γ1 ≥ α, use the dominant wavelength to detect the sample;

[0115] If the initial luminous flux of the main wavelength is not less than the luminous flux threshold corresponding to the measurement item, that is, γ1≥α, that is, when the main wavelength is used to perform project detection on the sample, it can be guaranteed that the luminous flux that can be collected by the optical measurement component meets the requirements of the sample detection project, then the main wavelength is used to detect the sample to ensure the accuracy of the measurement project results.

[0116] 502. If γ1<α≤γ2, use the secondary wavelength to detect the sample.

[0117] If the initial luminous flux of the main wavelength is less than the luminous flux threshold corresponding to the measurement item, but the luminous flux corresponding to the measurement item is not greater than the initial luminous flux of the sub-wavelength, that is, γ1<α≤γ2, that is, when the sub-wavelength is used to perform item detection on the sample, it can be guaranteed that the luminous flux that can be collected by the optical measurement component meets the requirements of the sample detection item, then the sub-wavelength is used to detect the sample to ensure the accuracy of the measurement item results.

[0118] In an embodiment of the present invention, a detailed description is given of the process of implementing an anti-interference detection method by cutting wavelengths when performing item detection on samples using multiple wavelengths. When γ1≥α, the main wavelength is used to detect the sample, and when γ1<α≤γ2, the secondary wavelength is used to detect the sample, thereby improving the accuracy of the sample item detection results.

[0119] based on Figure 5 In the embodiment described above, when the initial luminous flux of the secondary wavelength is less than the luminous flux corresponding to the measurement item, that is, γ2<α, the following steps can be performed to achieve anti-interference measurement of the sample. For details, please refer to Figure 6 Another embodiment of the anti-interference detection method in the embodiment of the present invention includes:

[0120] 601. If γ2<α, then after increasing the intensity of the light source corresponding to the dominant wavelength and / or increasing the gain of the sensor circuit for collecting the light flux, obtain an initial light flux γ3 of the sample mixture under the illumination of the dominant wavelength;

[0121] If the initial luminous flux of the secondary wavelength is also less than the luminous flux threshold corresponding to the measurement item, that is, γ2<α, the initial luminous flux γ3 of the sample mixture under the main wavelength irradiation can be obtained again after increasing the intensity of the light source corresponding to the main wavelength and / or increasing the gain of the sensor circuit used to collect the luminous flux. When γ3≥α, the main wavelength is used to perform anti-interference detection on the sample.

[0122] It is easy to understand that in the embodiments of the present invention, whether increasing the intensity of the light source corresponding to the main wavelength or increasing the gain of the sensor circuit used to collect the luminous flux, the sensitivity of the optical detector can be improved. Regardless of which method is used, as long as the initial luminous flux of the main wavelength is ensured to be no less than the luminous flux threshold corresponding to the measurement item, accurate measurement of the sample measurement item can be achieved.

[0123] 602. If γ3 ≥ α, perform anti-interference detection on the sample using the main wavelength.

[0124] After increasing the intensity of the light source corresponding to the main wavelength and / or increasing the gain of the sensor circuit used to collect the luminous flux, as long as γ3≥α, that is, the initial luminous flux of the main wavelength is not less than the luminous flux threshold corresponding to the measurement item, the main wavelength can be used to perform anti-interference measurement on the sample to ensure the accuracy of the sample measurement item results.

[0125] In the embodiment of the present invention, a detailed description is given of how to implement anti-interference measurement of a sample when the initial luminous flux of the secondary wavelength is also less than the luminous flux threshold corresponding to the measurement item, thereby further improving the accuracy of the sample detection item results.

[0126] based on Figure 6 In the embodiment described above, after increasing the intensity of the light source corresponding to the dominant wavelength and / or increasing the gain of the sensor circuit for collecting the light flux, if the initial light flux of the sample mixture under the dominant wavelength is still less than the light flux threshold corresponding to the measurement item, that is, γ3 < α, the following steps can be performed to achieve accurate measurement of the sample detection item. For details, please refer to Figure 7 Another embodiment of the anti-interference detection method in the embodiment of the present invention includes:

[0127] 701. If γ3<α, dilute the sample mixture;

[0128] If, after increasing the intensity of the light source corresponding to the main wavelength and / or increasing the gain of the sensor circuit used to collect the luminous flux, the initial luminous flux of the re-acquired sample mixture under the irradiation of the main wavelength is still less than the luminous flux threshold corresponding to the measurement item, that is, γ3<α, the sample mixture can be further diluted, and after the sample is diluted, step 702 is executed.

[0129] 702. Obtain an initial light flux γ5 of the diluted sample mixture under the irradiation of the main wavelength;

[0130] After diluting the sample mixture, the initial light flux γ5 of the diluted sample mixture under the main wavelength is re-obtained, and when the obtained initial light flux γ5 is not less than the light flux threshold α corresponding to the measurement item, step 703 is executed.

[0131] 703. If γ5≥α, perform anti-interference detection on the sample using the main wavelength.

[0132] If the initial luminous flux of the sample mixture obtained after dilution under the main wavelength is not less than the luminous flux threshold corresponding to the measurement item, that is, γ5≥α, then the main wavelength can continue to be used to perform anti-interference detection on the sample to achieve accurate measurement of the sample detection item.

[0133] In an embodiment of the present invention, a detailed description is given of how to implement anti-interference measurement of a sample when, after increasing the intensity of the light source corresponding to the main wavelength and / or increasing the gain of the sensor circuit used to collect the luminous flux, the initial luminous flux of the sample mixture under the irradiation of the main wavelength is still less than the luminous flux threshold corresponding to the measurement item, that is, γ3<α, thereby further improving the accuracy of the sample detection item results.

[0134] based on Figure 5 In the embodiment described above, when γ2<α, the following steps may be performed to achieve anti-interference measurement of the sample, see Figure 8 Another embodiment of the anti-interference detection method in the embodiment of the present invention includes:

[0135] 801. If γ2<α, then after increasing the intensity of the light source corresponding to the sub-wavelength and / or increasing the gain of the sensor circuit for collecting the light flux, obtain an initial light flux γ4 of the sample mixture under the illumination of the sub-wavelength;

[0136] If the initial luminous flux of the sub-wavelength is less than the luminous flux threshold corresponding to the measurement item, that is, γ2<α, it is also possible to increase the intensity of the light source corresponding to the sub-wavelength and / or increase the gain of the sensor circuit used to collect the luminous flux, and then re-obtain the initial luminous flux γ4 of the sample mixture under the sub-wavelength irradiation, and when γ4≥α, use the sub-wavelength to perform anti-interference detection on the sample.

[0137] It is easy to understand that in the embodiments of the present invention, whether increasing the intensity of the light source corresponding to the sub-wavelength or increasing the gain of the sensor circuit used to collect the luminous flux, it is a way to increase the initial luminous flux of the sub-wavelength. Regardless of which method is used, as long as the initial luminous flux of the sub-wavelength is ensured to be no less than the luminous flux threshold corresponding to the measurement item, accurate measurement of the sample measurement item can be achieved.

[0138] 802. If γ4≥α, perform anti-interference detection on the sample using the secondary wavelength.

[0139] After increasing the intensity of the light source corresponding to the sub-wavelength and / or increasing the gain of the sensor circuit used to collect the luminous flux, as long as γ4≥α, that is, the initial luminous flux of the sub-wavelength is not less than the luminous flux threshold corresponding to the measurement item, the sub-wavelength can be used to perform anti-interference measurement on the sample to ensure the accuracy of the sample measurement item results.

[0140] In the embodiment of the present invention, a detailed description is given of how to implement anti-interference measurement of a sample when the initial luminous flux of the secondary wavelength is less than the luminous flux threshold corresponding to the measurement item, thereby further improving the accuracy of the sample detection item results.

[0141] It should be noted that Figure 6 and Figure 8As two optional embodiments, since the main wavelength can better characterize the reaction process between the sample and the reagent, Figure 6 Example compared to Figure 8 In terms of embodiment, it is a more preferred embodiment.

[0142] based on Figure 8 In the embodiment described above, after increasing the intensity of the light source corresponding to the sub-wavelength and / or increasing the gain of the sensor circuit for collecting the light flux, if the initial light flux of the sample mixture under the sub-wavelength illumination is still less than the light flux threshold corresponding to the measurement item, that is, γ4<α, the following steps can be performed to achieve accurate measurement of the sample detection item. For details, please refer to Figure 9 Another embodiment of the anti-interference detection method in the embodiment of the present invention includes:

[0143] 901. If γ4<α, diluting the sample mixture;

[0144] If, after increasing the intensity of the light source corresponding to the sub-wavelength and / or increasing the gain of the sensor circuit used to collect the luminous flux, the initial luminous flux of the re-acquired sample mixture under the sub-wavelength irradiation is still less than the luminous flux threshold corresponding to the measurement item, that is, γ4<α, the sample mixture can be further diluted, and after the sample is diluted, step 902 is executed.

[0145] 902. Obtain an initial light flux γ6 of the diluted sample mixture under the illumination of the sub-wavelength;

[0146] After diluting the sample mixture, the initial light flux γ6 of the diluted sample mixture under the sub-wavelength illumination is re-obtained, and when the obtained initial light flux γ6 is not less than the light flux threshold α corresponding to the measurement item, step 903 is executed.

[0147] 903. If γ6 ≥ α, perform anti-interference detection on the sample using the secondary wavelength.

[0148] If the initial luminous flux of the sample mixture obtained after dilution under the sub-wavelength irradiation is not less than the luminous flux threshold corresponding to the measurement item, that is, γ6 ≥ α, then the sub-wavelength can continue to be used to perform anti-interference detection on the sample to achieve accurate measurement of the sample detection item.

[0149] In an embodiment of the present invention, a detailed description is given of how to implement anti-interference measurement of a sample when, after increasing the intensity of the light source corresponding to the sub-wavelength and / or increasing the gain of the sensor circuit used to collect the luminous flux, the initial luminous flux of the sample mixture under the sub-wavelength irradiation is still less than the luminous flux threshold corresponding to the measurement item, that is, γ4<α, thereby further improving the accuracy of the sample detection item results.

[0150] In the above embodiment, the anti-interference detection method for the sample when multiple wavelengths are used to perform project detection is described in detail. Next, the anti-interference detection method for the detection items that cannot be cut wavelength (i.e., single wavelength) is described, such as the anti-interference detection method of the chromogenic substrate method, wherein the anti-interference of a single wavelength has only a single threshold, i.e., the anti-interference threshold of the main wavelength.

[0151] For details, please refer to Figure 10 Another embodiment of the anti-interference detection method in the embodiment of the present invention includes:

[0152] 1001. When measuring the sample using a single wavelength, obtain the initial luminous flux of the sample mixture under the irradiation of the single wavelength.

[0153] When a single wavelength is used to measure the sample, the initial luminous flux of the sample mixture under the single wavelength irradiation is obtained. And according to the relationship between the initial luminous flux of a single wavelength and the luminous flux corresponding to the measurement item, perform the following steps.

[0154] 1002. If Then, the single wavelength is used to perform item detection on the sample;

[0155] If the initial luminous flux of a single wavelength is not less than the luminous flux corresponding to the measurement item, that is, That is, when a single wavelength is used to perform project detection on a sample, it can be ensured that the luminous flux that can be collected by the optical measurement component meets the requirements of the sample detection project, then the single wavelength is used to detect the sample to ensure the accuracy of the measurement project results.

[0156] 1003. If After increasing the intensity of the light source corresponding to the single wavelength and / or increasing the gain of the sensor circuit for collecting the light flux, the initial light flux of the sample mixture under the illumination of the single wavelength is obtained.

[0157] If the initial luminous flux of a single wavelength is less than the luminous flux corresponding to the measurement item, that is, When the light source intensity corresponding to the single wavelength is increased, and / or the sensor circuit gain for collecting the light flux is increased, the initial light flux of the sample mixture under the illumination of the single wavelength can be obtained again. And according to the initial luminous flux To determine the relationship between the luminous flux α corresponding to the measurement item, perform the following steps.

[0158] 1004. If then performing anti-interference detection on the sample using the single wavelength;

[0159] If after increasing the intensity of the light source corresponding to the single wavelength and / or increasing the gain of the sensor circuit for collecting the light flux, the initial light flux of the sample mixture obtained again under the illumination of the single wavelength is not less than the light flux threshold corresponding to the measurement item, that is, When the single wavelength is used, the sample can be subjected to anti-interference detection to achieve accurate measurement of the sample detection items.

[0160] 1005. If Then diluting the sample mixture;

[0161] If after increasing the intensity of the light source corresponding to a single wavelength and / or increasing the gain of the sensor circuit used to collect the luminous flux, the initial luminous flux of the sample mixture obtained under the irradiation of a single wavelength is still less than the luminous flux threshold corresponding to the measurement item, that is, When the sample mixture is diluted, step 1006 is executed after the dilution is completed.

[0162] 1006. Obtain the initial luminous flux of the diluted sample mixture under the irradiation of the single wavelength

[0163] After diluting the sample mixture, obtain the initial luminous flux of the diluted sample mixture under single wavelength irradiation And according to The relationship between the luminous flux α corresponding to the measurement item is determined, and step 1007 is executed.

[0164] 1007. If Then, the single wavelength is used to perform anti-interference detection on the sample.

[0165] If the initial luminous flux of the diluted sample mixture under the irradiation of a single wavelength is not less than the luminous flux threshold corresponding to the measurement item, that is, the luminous flux of the single wavelength can ensure the luminous flux collected by the optical measurement component, then the single wavelength is used to perform anti-interference detection on the sample to ensure the accuracy of the sample detection item results.

[0166] In the embodiment of the present invention, an anti-interference detection method for detection items that cannot be cut wavelength (ie, single wavelength) is described in detail, thereby improving the accuracy of the results of the single wavelength detection items of the sample.

[0167] The above describes the anti-interference detection method in the embodiment of the present invention in detail. The following describes the sample analyzer in the embodiment of the present invention in detail. Figure 11 , an embodiment of a sample analyzer in an embodiment of the present invention includes:

[0168] The measuring container 1101 is used to carry a mixture of a sample and a measuring reagent for executing the item;

[0169] An optical device 1102 is configured to provide multi-wavelength light via a multi-wavelength light source 11021 and an optical processing device 11022, and to illuminate the mixed liquid with the multi-wavelength light, wherein the multi-wavelength light includes a main wavelength and a sub-wavelength corresponding to a measurement item of the sample;

[0170] A light flux collection device 1103 is used to obtain initial light fluxes γ1 and γ2 of the sample mixture under the illumination of the main wavelength and the sub-wavelength respectively;

[0171] Processor 1104 is configured to:

[0172] Obtaining a luminous flux threshold α corresponding to the measurement item;

[0173] According to the comparison results of γ1, γ2 and α, an anti-interference detection method is applied to the sample.

[0174] Preferably, the processor 1104 is specifically configured to:

[0175] If γ1≥α, the sample is detected using the dominant wavelength;

[0176] If γ1<α≤γ2, the sub-wavelength is used to detect the sample.

[0177] Preferably, the processor 1104 is further configured to:

[0178] If γ1<α, then after increasing the intensity of the light source corresponding to the dominant wavelength and / or increasing the gain of the sensor circuit for collecting the light flux, obtaining the initial light flux γ3 of the sample mixture under the illumination of the dominant wavelength;

[0179] If γ3≥α, anti-interference detection is performed on the sample using the main wavelength.

[0180] Preferably, the processor 1104 is further configured to:

[0181] If γ2<α, then after increasing the intensity of the light source corresponding to the sub-wavelength and / or increasing the gain of the sensor circuit for collecting the light flux, obtaining the initial light flux γ4 of the sample mixture under the illumination of the sub-wavelength;

[0182] If γ4≥α, anti-interference detection is performed on the sample using the secondary wavelength.

[0183] Preferably, the processor 1104 is further configured to:

[0184] If γ3<α, dilute the sample mixture;

[0185] Obtaining an initial light flux γ5 of the diluted sample mixture under irradiation with the main wavelength;

[0186] If γ5≥α, anti-interference detection is performed on the sample using the main wavelength.

[0187] Preferably, the processor 1104 is further configured to:

[0188] If γ4<α, dilute the sample mixture;

[0189] Obtaining an initial light flux γ6 of the diluted sample mixture under the irradiation of the sub-wavelength;

[0190] If γ6≥α, anti-interference detection is performed on the sample using the secondary wavelength.

[0191] Preferably, the processor 1104 is further configured to:

[0192] When a single wavelength is used to measure the sample, the initial light flux of the sample mixture under the illumination of the single wavelength is obtained.

[0193] like Then, the single wavelength is used to perform item detection on the sample.

[0194] Preferably, the processor 1104 is further configured to:

[0195] like After increasing the intensity of the light source corresponding to the single wavelength and / or increasing the gain of the sensor circuit for collecting the light flux, the initial light flux of the sample mixture under the illumination of the single wavelength is obtained.

[0196] like Then, the single wavelength is used to perform anti-interference detection on the sample.

[0197] Preferably, the processor 1104 is further configured to:

[0198] like Then diluting the sample mixture;

[0199] Obtain the initial luminous flux of the diluted sample mixture under the irradiation of the single wavelength

[0200] like Then, the single wavelength is used to perform anti-interference detection on the sample.

[0201] It should be noted that the functions of each device in this embodiment are similar to those of Figures 4 to 10 The description in the embodiment is similar and will not be repeated here.

[0202] In the technical solution provided by the embodiment of the present invention, a sample mixture is obtained by adding a reagent for performing item detection to the sample in the measuring container 1101 and mixing it; the sample mixture is irradiated with multi-wavelength light provided by a multi-wavelength light source 11021 and an optical processor device 11022, and the multi-wavelength light includes a main wavelength and a sub-wavelength corresponding to the measurement item of the sample; the initial light flux γ1 of the main wavelength, the initial light flux γ2 of the sub-wavelength, and the light flux threshold α corresponding to the measurement item are obtained by the light flux acquisition device 1103 and the processor 1104; based on the comparison result of γ1, γ2 and α, an anti-interference detection method is adopted for the sample, that is, anti-interference measurement of the sample is realized under the premise of no pre-detection of sample interferents.

[0203] In addition, when the sample analyzer is performing a coagulation test, the sample analyzer is a coagulation analyzer, wherein the structural components and working principle of the coagulation analyzer can refer to Figures 4 to 10 The embodiments described above will not be described in detail here.

[0204] An embodiment of the present invention further provides a computer-readable storage medium, which is used to implement the functions of a sample analyzer and stores a computer program. When the computer program is executed by a processor, the processor can be configured to perform the following steps:

[0205] Add the reagent for performing the test item to the sample and mix well to obtain a sample mixture;

[0206] Irradiating the sample mixture with multi-wavelength light, wherein the multi-wavelength light includes a main wavelength and a sub-wavelength corresponding to a measurement item of the sample;

[0207] Obtaining an initial luminous flux γ1 of the main wavelength, an initial luminous flux γ2 of the sub-wavelength, and a luminous flux threshold α corresponding to the measurement item;

[0208] According to the comparison results of γ1, γ2 and α, an anti-interference detection method is applied to the sample.

[0209] In some embodiments of the present invention, when a computer program stored in a computer-readable storage medium is executed by a processor, the processor may further be configured to perform the following steps:

[0210] If γ1≥α, the sample is detected using the dominant wavelength;

[0211] If γ1<α≤γ2, the sub-wavelength is used to detect the sample.

[0212] In some embodiments of the present invention, when a computer program stored in a computer-readable storage medium is executed by a processor, the processor may further be configured to perform the following steps:

[0213] If γ2<α, then after increasing the intensity of the light source corresponding to the dominant wavelength and / or increasing the gain of the sensor circuit for collecting the light flux, obtaining the initial light flux γ3 of the sample mixture under the illumination of the dominant wavelength;

[0214] If γ3≥α, anti-interference detection is performed on the sample using the main wavelength.

[0215] In some embodiments of the present invention, when a computer program stored in a computer-readable storage medium is executed by a processor, the processor may further be configured to perform the following steps:

[0216] If γ2<α, then after increasing the intensity of the light source corresponding to the sub-wavelength and / or increasing the gain of the sensor circuit for collecting the light flux, obtaining the initial light flux γ4 of the sample mixture under the illumination of the sub-wavelength;

[0217] If γ4≥α, anti-interference detection is performed on the sample using the secondary wavelength.

[0218] In some embodiments of the present invention, when a computer program stored in a computer-readable storage medium is executed by a processor, the processor may further be configured to perform the following steps:

[0219] If γ3<α, dilute the sample mixture;

[0220] Obtaining an initial light flux γ5 of the diluted sample mixture under irradiation with the main wavelength;

[0221] If γ5≥α, anti-interference detection is performed on the sample using the main wavelength.

[0222] In some embodiments of the present invention, when a computer program stored in a computer-readable storage medium is executed by a processor, the processor may further be configured to perform the following steps:

[0223] If γ4<α, dilute the sample mixture;

[0224] Obtaining an initial light flux γ6 of the diluted sample mixture under the irradiation of the sub-wavelength;

[0225] If γ6≥α, anti-interference detection is performed on the sample using the secondary wavelength.

[0226] In some embodiments of the present invention, when a computer program stored in a computer-readable storage medium is executed by a processor, the processor may further be configured to perform the following steps:

[0227] When a single wavelength is used to measure the sample, the initial light flux of the sample mixture under the illumination of the single wavelength is obtained.

[0228] like Then, the single wavelength is used to perform item detection on the sample.

[0229] In some embodiments of the present invention, when a computer program stored in a computer-readable storage medium is executed by a processor, the processor may further be configured to perform the following steps:

[0230] like After increasing the intensity of the light source corresponding to the single wavelength and / or increasing the gain of the sensor circuit for collecting the light flux, the initial light flux of the sample mixture under the illumination of the single wavelength is obtained.

[0231] like Then, the single wavelength is used to perform anti-interference detection on the sample.

[0232] In some embodiments of the present invention, when a computer program stored in a computer-readable storage medium is executed by a processor, the processor may further be configured to perform the following steps:

[0233] like Then diluting the sample mixture;

[0234] Obtain the initial luminous flux of the diluted sample mixture under the irradiation of the single wavelength

[0235] like Then, the single wavelength is used to perform anti-interference detection on the sample.

[0236] Those skilled in the art will clearly understand that, for the convenience and brevity of description, the specific working processes of the systems, devices and units described above can refer to the corresponding processes in the aforementioned method embodiments and will not be repeated here.

[0237] In the several embodiments provided by the present invention, it should be understood that the disclosed systems, devices and methods can be implemented in other ways. For example, the device embodiments described above are merely illustrative. For example, the division of the units is merely a logical function division. In actual implementation, there may be other division methods, such as multiple units or components can be combined or integrated into another system, or some features can be ignored or not executed. In addition, the mutual coupling or direct coupling or communication connection shown or discussed can be an indirect coupling or communication connection through some interface, device or unit, which can be electrical, mechanical or other forms.

[0238] The units described as separate components may or may not be physically separate, and the components shown as units may or may not be physical units, that is, they may be located in one place or distributed across multiple network units. Some or all of these units may be selected to achieve the purpose of this embodiment according to actual needs.

[0239] In addition, the functional units in the various embodiments of the present invention may be integrated into a single processing unit, each unit may exist physically separately, or two or more units may be integrated into a single unit. The aforementioned integrated units may be implemented in the form of hardware or software functional units.

[0240] If the integrated unit is implemented in the form of a software functional unit and sold or used as an independent product, it can be stored in a computer-readable storage medium. Based on this understanding, the technical solution of the present invention, or the part that contributes to the prior art, or all or part of the technical solution can be embodied in the form of a software product. The computer software product is stored in a storage medium and includes several instructions for enabling a computer device (which can be a personal computer, server, or network device, etc.) to execute all or part of the steps of the method described in each embodiment of the present invention. The aforementioned storage medium includes: various media that can store program codes, such as a USB flash drive, a mobile hard disk, a read-only memory (ROM), a random access memory (RAM), a magnetic disk or an optical disk.

[0241] As described above, the above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit the same. Although the present invention has been described in detail with reference to the above embodiments, those skilled in the art should understand that the technical solutions described in the above embodiments can still be modified, or some of the technical features thereof can be replaced by equivalents. However, these modifications or replacements do not deviate the essence of the corresponding technical solutions from the spirit and scope of the technical solutions of the embodiments of the present invention.

Claims

1. An anti-interference detection method, characterized in that: include: Adding a reagent for performing a measurement item test to the sample and mixing the mixture to obtain a sample mixture; Before performing measurement item detection on the sample mixture, irradiating the sample mixture with multi-wavelength light, wherein the multi-wavelength light includes a main wavelength and a sub-wavelength corresponding to the measurement item of the sample; Obtaining an initial luminous flux γ1 of the main wavelength, an initial luminous flux γ2 of the sub-wavelength, and a luminous flux threshold α corresponding to the measurement item; When the multi-wavelength light is used to perform a measurement item detection on the sample mixture, an anti-interference detection method is used for the sample according to the comparison result of γ1, γ2 and α; The anti-interference detection method is applied to the sample according to the comparison results of γ1, γ2 and α, including: If γ1≥α, the sample is detected using the dominant wavelength; If γ1<α≤γ2, the sample is detected using the secondary wavelength; If γ2<α: (1) after increasing the intensity of the light source corresponding to the dominant wavelength and / or increasing the gain of the sensor circuit for collecting the luminous flux, obtain the initial luminous flux γ3 of the sample mixture under the irradiation of the dominant wavelength; if γ3≥α, perform anti-interference detection on the sample using the dominant wavelength; or, (2) After increasing the intensity of the light source corresponding to the sub-wavelength and / or increasing the gain of the sensor circuit for collecting the luminous flux, the initial luminous flux γ4 of the sample mixture under the irradiation of the sub-wavelength is obtained; if γ4 ≥ α, the sub-wavelength is used to perform anti-interference detection on the sample.

2. The method according to claim 1, characterized in that The method further comprises: If γ3<α, dilute the sample mixture; Obtaining an initial light flux γ5 of the diluted sample mixture under irradiation with the main wavelength; If γ5≥α, anti-interference detection is performed on the sample using the main wavelength.

3. The method according to claim 1, characterized in that The method further comprises: If γ4<α, dilute the sample mixture; Obtaining an initial light flux γ6 of the diluted sample mixture under the irradiation of the sub-wavelength; If γ6≥α, anti-interference detection is performed on the sample using the secondary wavelength.

4. The method according to any one of claims 1 to 3, characterized in that The method further comprises: When a single wavelength is used to measure the sample, the initial light flux of the sample mixture under the illumination of the single wavelength is obtained. like Then, the single wavelength is used to perform item detection on the sample.

5. The method according to claim 4, characterized in that The method further comprises: like After increasing the intensity of the light source corresponding to the single wavelength and / or increasing the gain of the sensor circuit for collecting the light flux, the initial light flux of the sample mixture under the illumination of the single wavelength is obtained. like Then, the single wavelength is used to perform anti-interference detection on the sample.

6. The method according to claim 5, characterized in that The method further comprises: like Then diluting the sample mixture; Obtain the initial luminous flux of the diluted sample mixture under the irradiation of the single wavelength like Then, the single wavelength is used to perform anti-interference detection on the sample.

7. A sample analyzer, characterized in that: include: A measuring container for carrying a mixture of a sample and a measuring reagent for performing a measurement item; an optical device for providing multi-wavelength light, and irradiating the sample mixture with the multi-wavelength light before performing a measurement item detection on the sample mixture, wherein the multi-wavelength light includes a main wavelength and a sub-wavelength corresponding to the measurement item of the sample; A light flux collection device, used to obtain initial light fluxes γ1 and γ2 of the sample mixture under the irradiation of the main wavelength and the sub-wavelength respectively; Processor for: Obtaining a luminous flux threshold α corresponding to the measurement item; When the multi-wavelength light is used to perform a measurement item detection on the sample mixture, an anti-interference detection method is used for the sample according to the comparison result of γ1, γ2 and α; The processor is specifically configured to: If γ1≥α, the sample is detected using the dominant wavelength; If γ1<α≤γ2, the sample is detected using the secondary wavelength; If γ1<α: (1) after increasing the intensity of the light source corresponding to the dominant wavelength and / or increasing the gain of the sensor circuit for collecting the luminous flux, obtain the initial luminous flux γ3 of the sample mixture under the irradiation of the dominant wavelength; if γ3≥α, perform anti-interference detection on the sample using the dominant wavelength; or, (2) After increasing the intensity of the light source corresponding to the sub-wavelength and / or increasing the gain of the sensor circuit for collecting the luminous flux, the initial luminous flux γ4 of the sample mixture under the irradiation of the sub-wavelength is obtained; if γ4 ≥ α, the sub-wavelength is used to perform anti-interference detection on the sample.

8. The sample analyzer according to claim 7, characterized in that: The processor is further configured to: If γ3<α, dilute the sample mixture; Obtaining an initial light flux γ5 of the diluted sample mixture under irradiation with the main wavelength; If γ5≥α, anti-interference detection is performed on the sample using the main wavelength.

9. The sample analyzer according to claim 7, wherein: The processor is further configured to: If γ4<α, dilute the sample mixture; Obtaining an initial light flux γ6 of the diluted sample mixture under the irradiation of the sub-wavelength; If γ6≥α, anti-interference detection is performed on the sample using the secondary wavelength.

10. The sample analyzer according to any one of claims 7 to 9, characterized in that: The processor is further configured to: When a single wavelength is used to measure the sample, the initial light flux of the sample mixture under the illumination of the single wavelength is obtained. like Then, the single wavelength is used to perform item detection on the sample.

11. The sample analyzer according to claim 10, characterized in that: The processor is further configured to: like After increasing the intensity of the light source corresponding to the single wavelength and / or increasing the gain of the sensor circuit for collecting the light flux, the initial light flux of the sample mixture under the illumination of the single wavelength is obtained. like Then, the single wavelength is used to perform anti-interference detection on the sample.

12. The sample analyzer according to claim 11, wherein: The processor is further configured to: like Then diluting the sample mixture; Obtain the initial luminous flux of the diluted sample mixture under the irradiation of the single wavelength like Then, the single wavelength is used to perform anti-interference detection on the sample.

13. The sample analyzer according to any one of claims 7 to 9, and any one of claims 11 to 12, characterized in that: The sample analyzer is a coagulation analyzer.

14. A computer storage medium having a computer program stored thereon, characterized in that: When the computer program is executed by a processor, it is used to implement the anti-interference detection method according to any one of claims 1 to 6.

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