Locking Structure and External Anchor of Left Ventricular Volume Reduction Device

Abstract

The present invention discloses a locking structure, an external anchor and a left ventricular volume reduction device. The locking structure has a locking unit, and the locking unit has: a locking member that can be pressed against a tie rod, and the locking member is a locking block; a squeezing member that can press the locking member onto the tie rod, the squeezing member is a transmission rod, one end of the transmission rod is connected with a transmission shaft, and both ends of the transmission shaft are inserted through two opposite side ends in the middle of the locking block, and the locking block is pushed and pulled by the transmission rod to achieve locking and unlocking. By improving the structure of the locking structure, the present invention further reduces the risk of the external anchor slipping off the tie rod, and retrieves the external anchor by unlocking the locking structure; moreover, the locking and unlocking of the locking structure and the tie rod are operated in the same direction, which is very convenient.

Description

Technical Field

[0001] The present invention belongs to the technical field of medical devices, and particularly relates to a locking structure and an external anchor of a left ventricular volume reduction device. Background Art

[0002] Left ventricular aneurysm (LVA) is a common complication after myocardial infarction. It is because after myocardial infarction in the left ventricle, part of the ventricular muscle becomes ischemic and necrotic. Since the necrotic ventricular muscle loses its contractile function, this part of the necrotic myocardium will protrude outward during the cardiac contraction of the patient, thus leading to the occurrence of ventricular aneurysm. Due to the compensatory effect of the heart, the heart continuously enlarges by a certain volume, and then heart failure, pulmonary congestion and other conditions occur.

[0003] Left ventricular volume reduction is a transcatheter ventricular augmentation system that can be used to solve the problem of scar tissue in patients with ischemic cardiomyopathy after myocardial infarction. The left ventricular volume reduction device delivers multiple pairs of anchors (including internal anchors and external anchors) into the body. They can clamp the left ventricle and allow other surgical instruments to enter the heart through a small incision on the body surface. This minimally invasive system can also be used in traditional open-chest surgery to achieve ventricular repair. In the prior art, the principle of combining the internal and external anchors is through a tie rod connection between the internal and external anchors. One end of the tie rod is fixed to the internal anchor, and the other end of the tie rod is locked by the locking structure of the external anchor. At the same time, in the prior art, the control direction of locking and unlocking the external anchor is perpendicular to the tie rod, and a special instrument is required to cooperate with the locking structure from the direction perpendicular to the tie rod, which not only increases the difficulty of the operation, is extremely inconvenient, but also requires more invasive measures for the patient, which is not conducive to the health of the patient. Therefore, it is necessary to develop a more integrated and stable external anchor (especially the locking structure) to solve the above problems. Summary of the Invention

[0004] One object of the present invention is to provide a locking structure for a left ventricular volume reduction device with a completely different structure.

[0005] The locking structure of the left ventricular volume reduction device of the present invention has a locking unit, and the locking unit has:

[0006] A locking member that can be pressed against the tie rod, and the locking member is a lock block;

[0007] A squeezing member that can press the locking member against the tie rod, the squeezing member is a transmission rod, one end of the transmission rod is connected with a transmission shaft, and both ends of the transmission shaft are inserted through two opposite side ends in the middle of the lock block, and the lock block is locked and unlocked by pushing and pulling the transmission rod.

[0008] Preferably,

[0009] One side of the lock block is internally provided with a positioning shaft which is parallel to the transmission shaft. The lock block is pushed and pulled by the transmission rod, and with the positioning shaft as the axis, the other side surface of the lock block is pushed to extrude against the surface of the tie rod to achieve locking.

[0010] Preferably, the locking structure further has a housing which internally houses the locking unit:

[0011] The two opposite first shell walls of the housing respectively have positioning shaft support holes, and the two ends of the positioning shaft are respectively fixed in the positioning shaft support holes;

[0012] One second shell wall of the housing has a transmission rod hole, and the other end of the transmission rod is inserted into the transmission rod hole.

[0013] Preferably,

[0014] The middle part of the lock block has a hollow transmission cavity. One end of the transmission rod is located in the transmission cavity, and the two ends of the transmission shaft at one end of the transmission rod are inserted into the two opposite side walls of the transmission cavity of the lock block.

[0015] Preferably,

[0016] One end of the transmission rod is a cylindrical rod, and the transmission shaft is arranged at one end of the cylindrical rod;

[0017] The other end of the transmission rod is a screw rod. One end of the screw rod is threadedly connected inside the other end of the cylindrical rod, and the other end of the screw rod is arranged in the transmission rod hole on the second shell wall of the housing.

[0018] Preferably,

[0019] A right trapezoidal groove is provided on the side surface of the other section of the cylindrical rod.

[0020] Preferably,

[0021] The bottom surface of one end of the cylindrical rod is arranged in the form of an arc surface of a cylindrical side surface coaxial with the transmission shaft.

[0022] Preferably,

[0023] The locking unit has a U-shaped limiting groove for limiting the lock block, which is fixed inside the housing, and the other side of the lock block is limited in the U-shaped limiting groove.

[0024] Preferably, on the two opposite second shell walls of the housing, that is, on the same shell wall as the transmission rod hole, tie rod holes are respectively provided at the corresponding positions where the locking member locks the tie rod.

[0025] Another object of the present invention is to provide an external anchor for a left ventricular volume reduction device, having:

[0026] A flat cuboid-shaped outer anchor body;

[0027] A locking structure, characterized in that: the locking structure is the locking structure for the left ventricular volume reduction device of the present invention, and the locking structure is fixedly arranged at the central position of one side surface of the outer anchor body.

[0028] Preferably, the outer anchor body has:

[0029] A contact surface that can abut against the outer wall of the left ventricle; and

[0030] A non-contact surface opposite to the contact surface, and the locking structure is fixed at the central position of the non-contact surface.

[0031] Preferably, a through locking hole is provided at the central position of the outer anchor body, the locking hole is for threading the tie rod, and the second shell wall of the housing of the locking structure is fixedly arranged at the locking hole position of the outer anchor body.

[0032] Another object of the present invention is to provide a left ventricular volume reduction device, which includes:

[0033] A tie rod;

[0034] An inner anchor, which is threaded through the head end of the tie rod;

[0035] An outer anchor, which is threaded through the proximal section on the tie rod, and is characterized in that the outer anchor is the outer anchor for the left ventricular volume reduction device of the present invention.

[0036] Preferably, the tie rod has a square connection section, a guiding section and a needle section connected in sequence, the inner anchor is threaded through the head end of the square connection section, and the outer anchor is threaded through the proximal section of the square connection section.

[0037] Preferably, a stranding hole is provided at the head end of the square connection section, and the stranding hole can be threaded on the tie rod shaft on the inner anchor.

[0038] Preferably, the guiding section and the needle section respectively have wire guiding channels communicating with each other axially at the center.

[0039] Preferably, the guiding section is close to the head end of the square connection section and has a guiding hole for guiding the wire into the wire guiding channel.

[0040] Preferably, the inner anchor has:

[0041] A contact surface that can abut against the ventricular septum of the right ventricle; and

[0042] A non-contact surface opposite to the contact surface, characterized in that at least one side edge of the non-contact surface extends towards the middle direction of the non-contact surface to form a barb substantially parallel to the non-contact surface, and a guiding cavity for guiding the snare is formed in the space between the barb and the non-contact surface.

[0043] Preferably, two opposite side edges of the non-contact surface respectively extend towards the middle direction of the non-contact surface to form the barbs substantially parallel to the non-contact surface.

[0044] Preferably, there is a certain distance between the two barbs on two opposite side edges of the non-contact surface, and the distance forms a barb opening for the snare to enter the guiding cavity.

[0045] Preferably, the end point of the guiding cavity stops at the center of the side end of the inner anchor.

[0046] Preferably, a guiding bump protruding from the guiding cavity is provided at a position of the barb near the end point of the guiding cavity for indicating the guiding end point.

[0047] Preferably, the shape of the barb is U-shaped.

[0048] Preferably, the main body of the inner anchor is rectangular parallelepiped.

[0049] Preferably, a wire cavity for the guide wire to pass through is provided at the axial center of the inner anchor.

[0050] Preferably, the side end of the inner anchor is a spherical end face.

[0051] Preferably, the contact surface of the inner anchor has a tie rod groove along the axial direction for accommodating and limiting the tie rod.

[0052] Preferably, a hinge part and a tie rod shaft for passing through the tie rod and spanning the tie rod groove are respectively provided on both sides of the tie rod groove at the middle of the contact surface of the inner anchor, and both ends of the tie rod shaft are respectively fixed at the middle of the hinge part.

[0053] Preferably, the cross section of the inner anchor is I-shaped.

[0054] The positive and progressive effects of the present invention are as follows:

[0055] 1. By improving the structure of the locking structure, the present invention provides a brand-new locking structure, reduces the risk of the outer anchor slipping off the tie rod, and retrieves the outer anchor by unlocking the locking structure.

[0056] 2. The control direction of locking and dissociating the outer anchor of the present invention is in the same direction as the tie rod, which greatly reduces the difficulty of operating locking and unlocking.

[0057] 3. The present invention improves the grasping force between the outer anchor and the tie rod by providing a locking structure with a toothed surface on the outer anchor, thereby reducing the risk of the outer anchor falling off in the body.

[0058] 4. The present invention provides barbs on the non-contact surface of the inner anchor, which can be hooked by a snare. Thus, when the operation fails or the inner anchor needs to be removed subsequently, the snare only needs to be hooked on the barbs of the inner anchor to pull the inner anchor out of the body from the delivery sheath, without the need for thoracotomy. It has the function of secondary intervention recovery, increasing the error tolerance rate of the operation, reducing the economic burden on patients, avoiding high-risk operations such as open-heart surgery, and benefiting patients. BRIEF DESCRIPTION OF THE DRAWINGS

[0059] Figure 1 is a three-dimensional structural schematic diagram of the left ventricular volume reduction device of the present invention;

[0060] Figure 2 is a structural schematic diagram of the tie rod 10 of the present invention;

[0061] Figures 3A to 3D is a structural schematic diagram of the retrievable inner anchor of the present invention;

[0062] Figure 3E is a schematic diagram of the retrieval process of the retrievable inner anchor of the present invention;

[0063] Figures 4A to 4F is a structural schematic diagram of the locking structure of the present invention;

[0064] Figures 5A to 5D is a structural schematic diagram of the implantation process of the left ventricular volume reduction device of the present invention. DETAILED DESCRIPTION OF THE INVENTION

[0065] In order to make the technical means, creative features, achieved purposes and functions of the present invention easy to understand, the present invention will be further described below with reference to specific drawings.

[0066] In the field of interventional medical devices, "distal" is defined as the end far from the operator during the operation, and "proximal" is defined as the end close to the operator during the operation.

[0067] In the present invention, unless otherwise clearly defined and limited, terms such as "installation", "connection", "connection", "fixation" should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral body; it can be a mechanical connection, an electrical connection, or a communication connection; it can be a direct connection, or an indirect connection through an intermediate medium, and can be the internal communication of two components or the interaction relationship between two components, unless otherwise clearly limited. For those of ordinary skill in the art, the specific meanings of the above terms in the present invention can be understood according to specific situations.

[0068] The lock release part referred to in the present invention refers to a device that can lock or unlock the locking structure in the conveying device.

[0069] As Figure 1 shown, the left ventricular volume reduction device of the present invention includes a tie rod 10, an inner anchor 20 and an outer anchor 30. The inner anchor 20 can be hinged to the distal end of the tie rod 10; the outer anchor 30 is threaded through the tie rod 10. The left ventricular volume reduction device provided by the present invention embeds the inner and outer anchors into the ventricular wall and sutures the redundant scar tissue to help the heart restore its previous shape and function.

[0070] The tie rod of the present invention can be an ordinary tie rod in the prior art, such as Figure 4A the straight rod shown; it can also be a three-section type. As Figure 2 described, the tie rod 10 has a square connecting section 11, a guiding section 12 and a needle section 13 from the distal end to the proximal end. The square connecting section 11, the guiding section 12 and the needle section 13 are integrally formed in the order from the distal end to the proximal end. The proximal needle section 13 is made of a high-hardness metal such as stainless steel or a polymer material. The distal end of the connecting section 11 has a stranding hole 111. The guiding section 12 and the axial center of the needle 13 section respectively have a wire guiding channel that communicates with each other. The head end of the guiding section 12 close to the connecting section 11 has a guiding hole 121 for the wire to penetrate into the wire guiding channel. The tie rod 10 can be made of a polymer material such as stainless steel, platinum iridium alloy, PEEK, etc.

[0071] The inner anchor of the present invention can be an inner anchor in any structural form in the prior art as long as it can be arranged on the right ventricular septum of the heart. However, in order to reduce the surgical risk of thoracotomy after the implantation operation of the heart volume reduction device fails or the patient needs to remove the left ventricular volume reduction device in the later stage, the present invention Figures 3A to 3EProvide an exemplary retrievable inner anchor 20. The main body of the retrievable inner anchor 20 is generally cuboid-shaped, having two sides, one side is the contact surface 21 and the other side is the non-contact surface 22. The contact surface 21 refers to the side that fits against the ventricular septum of the right ventricle of the heart after implantation; the non-contact surface 22 refers to the side that will not stick to the heart after implantation, that is, the side opposite to the contact surface 21. The axial center of the inner anchor 20 has a guide wire cavity 213 for the guide wire to pass through when the inner anchor is delivered during the operation. The cross-section of the guide wire cavity 23 can be square, circular, or any other hollow inner cavity of any shape as long as it can allow the guide wire to pass through. Preferably, it is a circular through hole. The side end of the inner anchor 20 can be any smooth curved surface shape, preferably a spherical end face. The spherical end face is beneficial for the inner anchor 21 to smoothly enter the delivery sheath and reduce the delivery resistance. The contact surface 21 can abut against the ventricular septum of the right ventricle. The contact surface 21 can be without a tie rod groove as in the prior art. During the delivery of the inner anchor, the tie rod 10 closely adheres to the contact surface 21. In order to reduce the size of the delivery sheath, a better way is to axially provide a tie rod groove 211 on the contact surface 21. During the delivery of the inner anchor, the tie rod 10 is accommodated in the tie rod groove 211, reducing the volume of the inner anchor and the tie rod during the delivery process; at the same time, the tie rod groove 211 also limits the tie rod 10. The tie rod 10 is constrained in the tie rod groove 211 to regulate the movement of the tie rod 10 and avoid damage to the heart tissue. The tie rod 10 can be pivotally connected to the middle of the contact surface 21. A better way is an irreversible way. For example, in the middle of the contact surface 21, there are hinge parts 212 located on both sides of the tie rod groove 211 and a tie rod shaft 213 for passing through the tie rod 10 across the tie rod groove 211. The two ends of the tie rod shaft 213 are respectively fixed in the middle of the hinge part 212. The hinge part 212 serves as the support point for the two ends of the tie rod shaft 213. The tie rod shaft 213 cannot be removed from the hinge part 212. The hinge hole 111 of the tie rod 10 is passed through the tie rod shaft 213 on the inner anchor 20.

[0072] The non-contact surface 22 of the retrievable inner anchor 20 faces away from the contact surface 21. At least one side of the non-contact surface 22 extends a barb 221 substantially parallel to the non-contact surface 22 toward the middle of the non-contact surface 22, which is conducive to the snare 91 capturing the inner anchor 20. A better way is that the two opposite sides of the non-contact surface 22 respectively extend barbs 221 substantially parallel to the non-contact surface 22 toward the middle of the non-contact surface 22, and both sides have barbs, which is more conducive to the snare 91 capturing the inner anchor 20. The barbs 221 extend from both sides of the non-contact surface 22, so that the cross section of the inner anchor is I-shaped. The I-shaped cross section is conducive to the snare wire being accumulated in the cavity of the I-shaped cross section of the inner anchor when the snare 91 drives the inner anchor 20 to be withdrawn, thereby reducing the resistance to withdrawing the inner anchor 20. The barb 221 may be in the shape of a long plate, but the shape of the barb may be U-shaped, which reduces the endothelial attachment growth of the inner anchor 20 in the body and facilitates subsequent recovery. The space between the barb 221 and the non-contact surface 22 forms a guide cavity 222 that can provide guidance for the snare 91. The recyclable inner anchor 20 is provided with a barb 221 on one side of the inner anchor for the snare 91 to hook and pull, so that the inner anchor 20 is pulled back from the delivery sheath to complete the recovery of the inner anchor 20, and no additional open-heart surgery is required to remove the inner anchor. In the case where the barbs 221 extend from both opposite sides of the non-contact surface 22, there is a certain distance between the two barbs 221 on the two opposite sides of the non-contact surface 22, that is, the two barbs 221 are not butted together, and at this time, the distance forms a barb opening 223 that can capture the snare 91 to enter the guide cavity 222. At this time, the guide cavity 222 extends from the barb opening 223 as the starting point along the straight line parallel to the non-contact surface 22 of the inner anchor. When it extends to the side end position of the inner anchor 20 but has not yet reached, the guide cavity 222 begins to bend and extend in the direction of the axis of the inner anchor 20, and finally the guide cavity 222 ends at the axis of the side end of the inner anchor 20, that is, the guide cavity 222 ends at the guide wire cavity 23 at the axial center. Such a setting can make the snare 91 hung in the guide cavity 222 be located at the center of the inner anchor 20 when the inner anchor is recovered, which is beneficial to the movement guidance of the snare 91. When the snare captures the inner anchor 20, it is located at the center of the inner anchor 20, which is beneficial to the entry of the inner anchor 20 into the delivery sheath. In addition, the barb 221 has a guide protrusion 224 protruding from the guide cavity 222 at the end point of the guide cavity 222 to indicate the end point of the guide. When the snare 91 moves to this position, in combination with the external imager, the snare completes the capture of the inner anchor 20, and the corresponding operation of withdrawing the snare 91 can be performed. The inner anchor 20 of this example can be integrally formed. The inner anchor material can be made of one or more combinations of metal materials with good biocompatibility and toughness such as stainless steel, titanium, nickel-titanium alloy, etc. The contact surface of the inner anchor or the entire inner anchor can also be covered with a polyester coating or surface coating treatment, so that the coating can buffer the contact between the inner anchor and the heart tissue, and at the same time can increase the speed of endothelialization and reduce the corresponding inflammatory response.

[0073] The outer anchor of the present invention can be an outer anchor of any structure in the prior art, which is used to exclude the left ventricular scar structure. For example Figures 4A to 4B As shown, an outer anchor of one structural form, such as outer anchor 30, is generally in the shape of a flat cuboid, having an outer anchor body 30a. The outer anchor body also has two sides, a contact surface and a non-contact surface. The contact surface can abut against the outer wall of the left ventricle, and the non-contact surface faces away from the contact surface. A through locking hole (not shown in the figure) is provided at the center of the outer anchor body 30a, and the locking hole is for passing through the tie rod 10. The outer anchor material can be made of one or a combination of metal materials with good biocompatibility and toughness, such as stainless steel, titanium, nitinol, cobalt-chromium alloy, platinum-iridium alloy, etc. The contact surface of the outer anchor or the entire outer anchor body can also be covered with a polyester coating or surface coating treatment. The coating structure buffers the contact between the outer anchor and the heart tissue, and at the same time can increase the speed of endothelialization and reduce the corresponding inflammatory reaction.

[0074] In order to strengthen the firmness of the outer anchor 30 locked on the tie rod 10, a locking structure is provided on the non-contact surface at the position of the locking hole of the outer anchor body 30a. The locking structure of the present invention can be any structure that can tightly lock the outer anchor 30 and the tie rod 10 together. The locking structure exemplified by the present invention at least has a locking member and a squeezing member. In a preferred case, there can also be a reset member, or there can further be a cam, and there can further be a housing. The structures such as the locking member, the squeezing member, the reset member, and the housing can be various, as long as it is a structure that can lock the locking member on the tie rod, it is feasible. Any squeezing member that can squeeze the locking member on the tie rod 10 is also feasible. The reset member is a structure that can release the locking relationship of the locking member from the tie rod and release the locking member.

[0075] A locking structure exemplified by the present invention has a locking unit and a housing. The locking unit of the present invention can be a locking unit in the prior art or a locking unit in the applicant's prior patent application. See applications CN2022104104038 and CN2022104103800. This patent application has a locking member, a squeezing member, a pair of reset members, and a cam. This invention patent application includes all the technical contents of the above patent applications.

[0076] For example Figures 4A to 4F As shown, the present invention also exemplifies a locking structure that is simple in structure and controls in the same direction as the tie rod 10. This locking structure can also be unlocked to recover the outer anchor and the inner anchor. The locking structure of this example is also very convenient for locking and unlocking operations because it operates in the same direction as the tie rod 10. The locking structure of the present invention also has a locking unit, and the locking unit has: a locking member that can be pressed against the tie rod 10, a squeezing member that can press the locking member against the tie rod 10, and a housing.

[0077] In this example, the locking member is a locking block 31, which is roughly in the shape of a square block. One side surface is set as an arc of a smooth cylindrical side surface, and the other three side surfaces are still in a planar shape. The other side surface opposite to the arc-shaped side surface is the locking surface 311 for squeezing the tie rod 10. The locking surface 311 can be set as a toothed surface (not shown in the figure), for example, so that the tie rod 10 can be clamped more firmly. A positioning shaft 312 is arranged inside the locking block 31 on one side of the arc-shaped side surface, and both ends of the positioning shaft 312 are arranged on two opposite first shell walls of the housing. The locking block 31 can rotate around the positioning shaft 312, so as to push the locking surface 311 onto the surface of the tie rod 10 for squeezing and locking. A transmission cavity 313 is hollowed out near one side in the middle of the locking block 31.

[0078] In this example, the squeezing member is a transmission rod 32. One end of the transmission rod 32 is connected with a transmission shaft 321. The transmission shaft 321 is parallel to the positioning shaft 312. One end of the transmission rod 32 is located inside the transmission cavity 313, and the transmission shaft 321 is arranged inside the hollow transmission cavity 313 in the middle of the locking block 31. Both ends of the transmission shaft 321 pass through two opposite side walls of the transmission cavity 313. By pushing and pulling the transmission rod 32, with the positioning shaft 312 as the axis, the locking block 31 rotates, so that the locking surface 311 of the locking block 31 is pushed onto the surface of the tie rod 10 to achieve locking. On the contrary, pulling the transmission rod 32 makes the locking surface 311 of the locking block 31 disengage from the surface of the tie rod 10 for unlocking. Specifically, one end of the transmission rod 32 is a cylindrical rod 322, and the transmission shaft 321 is arranged at one end of the cylindrical rod 322. A right trapezoidal groove 324 is arranged on the side surface of the other end of the cylindrical rod 322, which is convenient for the accommodation and rotation of the locking block 31. The bottom surface of one end of the cylindrical rod 322 is set as an arc surface in the form of a cylindrical side surface coaxial with the transmission shaft 321, which is convenient for the accommodation and rotation of the cylindrical rod 322 inside the transmission cavity 313. The other end of the transmission rod 32 is a screw 323. One end of the screw 323 is threadedly connected inside the other end of the cylindrical rod 322, and the other end of the screw 323 is arranged inside the transmission rod hole on the second shell wall of the housing.

[0079] In this example, the housing 33 is a square box body, and a locking unit is arranged inside the housing 33. Positioning shaft support holes 331 are respectively provided on two opposite first shell walls of the housing 33, and both ends of the positioning shaft 312 of the locking block 31 are respectively fixed inside the positioning shaft support holes 331. A transmission rod hole 332 is provided on one second shell wall of the housing 33, and the other end of the screw 323 of the transmission rod 32 passes through the transmission rod hole 332. Tie rod holes 333 are respectively provided on two opposite second shell walls of the housing 33 at positions corresponding to the locking member locking the tie rod 10. The tie rod holes 333 and the transmission holes 332 are on the same side wall, so it is convenient for operation of locking and unlocking. The whole locking structure is fixedly connected to the lock hole at the center position of the non-contact surface of the outer anchor body 30 by borrowing the second shell wall with the tie rod hole 333 but without the transmission hole 332.

[0080] In this example, there is also a U-shaped limiting groove 34 with a limiting lock block 31. The limiting groove 34 is fixed inside the housing 33. The shape of the limiting groove 34 is roughly a U-shaped groove formed by two side plates and a bottom plate. The notches on both sides of the limiting groove 34 are aligned with the tie rod holes 333 of the housing 33 to facilitate the passing of the tie rod 10. The other side of the lock block 31 with a locking surface 311 is limited inside the U-shaped limiting groove 34.

[0081] As Figures 5A to 5D shown, the implantation process of the left ventricular volume reduction device of the present invention is as follows:

[0082] Use the proximal needle segment 13 on the tie rod 10 or other puncturing parts to complete the puncture of the left ventricular scar area and the interventricular septum area, enter the puncture sheath tube, establish a channel between the right ventricle and the epicardial area, withdraw the dilator in the puncture sheath tube, insert the J-shaped guide wire 92 along the puncture sheath tube, use the snare 91 in the delivery device to complete the capture of the J-shaped guide wire 92, keep the snare 91 in a tightened state on the J-shaped guide wire 92, withdraw the snare 91, and pull the J-shaped guide wire 92 into the inner cavity of the delivery device 90, and then out of the proximal end of the delivery device.

[0083] Adjust the puncture sheath tube so that the distal end of the puncture sheath tube enters the distal inner cavity of the delivery device 90. Insert the J-shaped guide wire 92 into the proximal needle segment 13 on the tie rod 10 outside the body, and insert the tie rod 10 connecting the inner anchor along the J-shaped guide wire 92. Keep the J-shaped guide wire 92 stationary and push the tie rod 10 so that the proximal end of the tie rod 10 successively enters the inner cavity of the delivery device 90, the distal inner cavity of the puncture sheath tube, the distal end of the delivery device 90, the right ventricle, the left ventricle, and the epicardial area. When the proximal end of the tie rod 10 exits the epicardium, the J-shaped guide wire 92 can be withdrawn, and pulling the tie rod 10 can complete the entry of the inner anchor 20.

[0084] Confirm the position of the inner anchor 20 through fluoroscopy of the imager. When the inner anchor 20 approaches the position of the right ventricular interventricular septum, withdraw the distal end of the puncture sheath tube to the left ventricle, and at the same time retract the delivery device 90 so that the inner anchor 20 can be released at the position of the right ventricular interventricular septum.

[0085] Cut the square connection section 11 at the connection between the square connection section 11 and the guiding section 12, adjust the locking structure of the outer anchor 30 to make it in a released state, and insert the outer anchor 30 along the square connection section 11 to ensure that the contact surface of the outer anchor 30 contacts the scar tissue in the epicardial area.

[0086] Shorten the distance between the inner anchor and the outer anchor, and at the same time maintain an appropriate compression force on the heart, which should not be too large or too small. The optimal force is 1-6 N. Operate the external locking and releasing part to lock the locking structure, and cut off the redundant square connection section 11 to complete the implantation of the left ventricular volume reduction device. Combining with the anatomical structure and actual needs of the patient's heart, repeat the above steps to implant multiple pairs of anchors, generally 2-4 pairs.

[0087] When the operation fails or the patient needs to remove the left ventricular volume reduction device, etc., the delivery device 90 is inserted along the right jugular vein, the dilator in the delivery device 90 is withdrawn, the snare 91 is inserted along the delivery device 90, and with the support of the imaging instrument, the snare is used to capture the barb opening 223 on the inner anchor 20, and the barb 221 of the inner anchor 20 is successfully captured. The snare 91 is tightened. When the snare 91 contacts the guiding bump 224, the imaging instrument prompts that the snare has completed the capture of the inner anchor. The external locking and releasing member is used to release the locking of the outer anchor 30 on the tie rod 10, and the snare is kept in a tightly bound state on the inner anchor 20. While withdrawing the snare, the inner anchor 20 is inserted into the delivery device 90, and the delivery device 90 is withdrawn, and the interventional recovery of the inner anchor 20 can be completed.

[0088] The left ventricular volume reduction device provided by the present invention uses a minimally invasive incision in the left anterior chest and interventional right internal jugular vein as the surgical approach. Under the condition that the heart does not stop beating, after using a guide wire to shuttle back and forth in the heart to "lay tracks", like tightening a pocket, the two anchors are accurately placed at the edge of the ventricular aneurysm, one on the left and one on the right, one inside and one outside, attacking from both sides, so that the ventricular aneurysm is folded and clamped, the scar area of the left ventricle and the right ventricle are folded together, a series of anchors are embedded in the ventricular wall, and the redundant scar tissue is sutured to help the heart restore its previous shape and function. The left ventricle of the patient is reshaped to be close to the normal shape and size, the ventricle is reshaped, and the heart function is helped to be improved, and the patient's symptoms and quality of life are improved. The left ventricular volume reduction device of the present invention has the function of retrievable intervention, avoiding open heart surgery when the patient needs to remove the left ventricular volume reduction device during or after the operation. The retrievable method reduces the secondary injury to the patient during the operation and reduces the economic burden on the patient and his family.

[0089] The above shows and describes the basic principles, main features and advantages of the present invention. Those skilled in the art should understand that the present invention is not limited by the above embodiments. What is described in the above embodiments and the specification only illustrates the principles of the present invention. Without departing from the spirit and scope of the present invention, the present invention will have various changes and improvements, and these changes and improvements all fall within the scope of the present invention claimed. The scope of protection claimed by the present invention is defined by the appended claims and their equivalents.

Claims

1. A locking structure for a left ventricular volume reduction device, characterized in that The locking structure has a locking unit, and the locking unit has: A locking member that can be pressed against the tie rod, wherein the locking member is a locking block; A compression piece capable of pressing the locking piece onto the tie rod, wherein the compression piece is a transmission rod, one end of which is connected to a transmission shaft, and both ends of the transmission shaft are passed through two opposite side ends of the middle of the locking block, and locking and unlocking are achieved by pushing and pulling the locking block by the transmission rod; A positioning shaft is provided in one side of the locking block, and the positioning shaft is parallel to the transmission shaft. The locking block is pushed and pulled by the transmission rod, and the other side of the locking block is pushed to be pressed against the surface of the tie rod with the positioning shaft as the axis to achieve locking; The locking structure further comprises a housing, wherein the locking unit is built in the housing: The two opposite first shell walls of the shell are respectively provided with positioning shaft support holes, and the two ends of the positioning shaft are respectively fixed in the positioning shaft support holes; A transmission rod hole is provided on a second shell wall of the shell, and the other end of the transmission rod is inserted into the transmission rod hole; The middle part of the locking block has a hollow transmission cavity, one end of the transmission rod is located in the transmission cavity, and two ends of the transmission shaft at one end of the transmission rod are inserted into two opposite side walls of the transmission cavity of the locking block; One end of the transmission rod is a cylindrical rod, and the transmission shaft is arranged on one end of the cylindrical rod; The other end of the transmission rod is a screw rod, one end of which is threadedly connected to the other end of the cylindrical rod, and the other end of the screw rod is arranged in the transmission rod hole of the second shell wall of the shell.

2. The locking structure for the left ventricular volume reduction device according to claim 1, characterized in that A right-angled trapezoidal groove is arranged on the side surface of the other section of the cylindrical rod.

3. The locking structure for the left ventricular volume reduction device according to claim 1, characterized in that The bottom surface of one end of the cylindrical rod is arranged to be an arc surface in the form of a cylindrical side surface coaxial with the transmission shaft.

4. The locking structure for the left ventricular volume reduction device according to claim 1, characterized in that The locking unit has a U-shaped limiting groove for limiting the locking block and is fixed in the housing. The other side of the locking block is limited in the U-shaped limiting groove.

5. The locking structure for the left ventricular volume reduction device according to claim 1, characterized in that Two opposite second shell walls of the shell, namely, on the same shell wall as the transmission rod hole, are respectively provided with tie rod holes at corresponding positions where the locking member locks the tie rod.

6. An external anchor for a left ventricular volume reduction device, comprising: An outer anchor body in the shape of a flat rectangular parallelepiped; A locking structure, characterized in that: The locking structure is the locking structure for the left ventricular volume reduction device according to any one of claims 1 to 5, and the locking structure is fixedly arranged at the center position of one side of the outer anchor body.

7. The external anchor for a left ventricular volume reduction device according to claim 6, characterized in that The outer anchor body comprises: a contact surface that can abut against the outer wall of the left ventricle; and A non-contact surface opposite to the contact surface, wherein the locking structure is fixed at a central position of the non-contact surface.

8. The outer anchor for a left ventricular volume reduction device according to claim 7, characterized in that The center position of the outer anchor body is provided with a through locking hole, the locking hole is used for passing the tie rod, and the second shell wall of the outer shell of the locking structure is fixedly arranged at the locking hole position of the outer anchor body.

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