An ultrasonic detection system, method, device, equipment and storage medium

Abstract

The present invention discloses an ultrasonic detection system, method, device, equipment and storage medium. The system includes an ultrasonic probe, a solid ultrasonic coupling agent, an electrical parameter measurement module and a processor, wherein: the solid ultrasonic coupling agent is a solid hydrogel and is fixed on the ultrasonic probe; the electrical parameter measurement module is respectively connected to both ends of the solid ultrasonic coupling agent through connecting wires and is used for measuring the electrical parameters of the solid ultrasonic coupling agent during ultrasonic detection; the processor is used for generating an ultrasonic detection image according to the ultrasonic signal collected by the ultrasonic probe and the electrical parameters. By utilizing the linear relationship between the piezoelectric effect characteristics of the solid hydrogel and the ultrasonic detection depth to perform standardized processing on the ultrasonic signal, the embodiments of the present invention realize the standardization of the ultrasonic signal, so that the ultrasonic detection image obtained based on the ultrasonic signal is not affected by the force applied during the operation of the physician, and the accuracy of the imaging result is ensured.

Description

Technical Field

[0001] The present invention relates to the technical field of ultrasonic imaging, and in particular to an ultrasonic detection system, method, device, equipment and storage medium. Background Art

[0002] Ultrasonic imaging technology observes by using the reflection of ultrasonic waves by the imaging object, and obtains an image of the imaging object by receiving and processing the reflected signals. In the medical field, ultrasonic imaging methods are often used to judge the position, size and shape of internal organs, determine the scope and physical properties of lesions, and provide anatomical diagrams of some glandular tissues, and are widely used in ophthalmology, obstetrics and gynecology, cardiovascular system, digestive system and urinary system.

[0003] In the process of implementing the present invention, it is found that there are at least the following technical problems in the prior art: Ultrasonic imaging examinations are usually carried out by a doctor placing a handheld probe on the patient and moving it for scanning to perform real-time imaging diagnosis. However, due to different forces applied by different doctors on the probe and the patient, the positions, sizes and shapes of internal organs, glands, lesions, etc. presented are different, and it is difficult to standardize ultrasonic imaging, which will also affect the doctor's more accurate result diagnosis. Summary of the Invention

[0004] The present invention provides an ultrasonic detection system, method, device, equipment and storage medium to solve the technical problems of inconsistent standards and inaccurate imaging results during ultrasonic imaging.

[0005] According to one aspect of the present invention, an ultrasonic detection system is provided, including an ultrasonic probe, a solid ultrasonic couplant, an electrical parameter measurement module and a processor, wherein:

[0006] The solid ultrasonic couplant is a solid hydrogel and is fixed on the ultrasonic probe;

[0007] The electrical parameter measurement module is respectively connected to both ends of the solid ultrasonic couplant through connecting wires, and is used to measure the electrical parameters of the solid ultrasonic couplant during ultrasonic detection;

[0008] The processor is used to generate an ultrasonic detection image according to the ultrasonic signal collected by the ultrasonic probe and the electrical parameters.

[0009] According to another aspect of the present invention, an ultrasonic detection method is provided, which is executed by the processor in the ultrasonic detection system provided by any embodiment of the present invention. The method includes:

[0010] Receiving the ultrasonic signal collected by the ultrasonic probe and the electrical parameters measured by the electrical parameter measurement module;

[0011] Generating an ultrasonic detection image according to the ultrasonic signal and the electrical parameters.

[0012] According to another aspect of the present invention, there is provided an ultrasonic detection device configured in a processor in the ultrasonic detection system provided in any embodiment of the present invention. The device includes:

[0013] A signal receiving module, configured to receive ultrasonic signals collected by an ultrasonic probe and electrical parameters measured by an electrical parameter measurement module;

[0014] An image generating module, configured to generate an ultrasonic detection image based on the ultrasonic signals and electrical parameters.

[0015] According to another aspect of the present invention, there is provided an electronic device, which includes:

[0016] At least one processor; and

[0017] A memory communicatively connected to the at least one processor; wherein,

[0018] The memory stores a computer program executable by the at least one processor. The computer program is executed by the at least one processor so that the at least one processor can execute the ultrasonic detection method of any embodiment of the present invention.

[0019] According to another aspect of the present invention, there is provided a computer-readable storage medium storing computer instructions for causing a processor to implement the ultrasonic detection method of any embodiment of the present invention when executed.

[0020] In the ultrasonic detection system according to the embodiment of the present invention, by fixing a solid ultrasonic couplant on the ultrasonic probe, during ultrasonic detection, an electrical parameter measurement module connected to both ends of the solid ultrasonic couplant through connecting wires measures the electrical parameters of the solid ultrasonic couplant during ultrasonic detection; the processor generates an ultrasonic detection image based on the ultrasonic signals collected by the ultrasonic probe and the electrical parameters. By using the linear relationship between the piezoelectric effect characteristics of the solid hydrogel and the ultrasonic detection depth to perform standardization processing on the ultrasonic signals, the standardization of the ultrasonic signals is achieved, so that the ultrasonic detection image obtained based on the ultrasonic signals is not affected by the force applied by the physician during operation, and the technical problems of inconsistent ultrasonic imaging standards and inaccurate imaging results caused by inconsistent physician operations in the prior art are solved.

[0021] It should be understood that the content described in this part is not intended to identify the key or important features of the embodiments of the present invention, nor is it used to limit the scope of the present invention. Other features of the present invention will become easily understood through the following description. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the following briefly introduces the drawings required for use in the description of the embodiments. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without creative work.

[0023] Figure 1 is a structural schematic diagram of an ultrasonic detection system provided in Embodiment 1 of the present invention;

[0024] Figure 2 is a flow chart of an ultrasonic detection method provided in Embodiment 2 of the present invention;

[0025] Figure 3a It is a schematic diagram of the test results of the fracture toughness test of a solid hydrogel provided in the third embodiment of the present invention;

[0026] Figure 3b is a stress-strain curve diagram of a fatigue resistance test of a solid hydrogel provided in Example 3 of the present invention;

[0027] Figure 3c This is a schematic diagram of the gap growth of a solid hydrogel under tensile strain provided in Example 3 of the present invention;

[0028] Figure 3d is a scatter plot of fatigue fracture energy of a solid hydrogel under stress provided by Example 3 of the present invention;

[0029] Figure 3e is a schematic diagram of the change in resistance of a solid hydrogel when subjected to force provided by the third embodiment of the present invention;

[0030] Figure 3f This is an ultrasonic image obtained by ultrasonic imaging using a solid hydrogel pad provided in Embodiment 3 of the present invention;

[0031] Figure 3g is a schematic diagram of ultrasound imaging provided by Embodiment 3 of the present invention;

[0032] Figure 3h This is a schematic diagram of the linear relationship between the change rate of the tungsten wire position and the change rate of the hydrogel resistance value provided in the third embodiment of the present invention;

[0033] Figure 4 is a structural schematic diagram of an ultrasonic detection device provided in Embodiment 4 of the present invention;

[0034] Figure 5 It is a structural schematic diagram of an electronic device provided in Embodiment 5 of the present invention. DETAILED DESCRIPTION

[0035] To enable those skilled in the art to better understand the solution of the present invention, the technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present invention without creative efforts shall fall within the protection scope of the present invention.

[0036] It should be noted that the terms "first", "second", etc. in the description and claims of the present invention and the above-mentioned drawings are used to distinguish similar objects, and are not necessarily used to describe a specific order or sequence. It should be understood that such data can be interchanged under appropriate circumstances so that the embodiments of the present invention described herein can be implemented in an order other than those illustrated or described herein. In addition, the terms "comprising" and "having" and any variations thereof are intended to cover non-exclusive inclusion. For example, a process, method, system, product or device that includes a series of steps or units does not necessarily have to be limited to those steps or units clearly listed, but may include other steps or units not clearly listed or inherent to these processes, methods, products or devices.

[0037] Embodiment 1

[0038] Figure 1 is a schematic structural diagram of an ultrasonic detection system provided in Embodiment 1 of the present invention. This embodiment is applicable to the situation during ultrasonic detection. As Figure 1 shown, the ultrasonic detection system provided in this embodiment includes: an ultrasonic probe 10, a solid ultrasonic couplant 20, an electrical parameter measurement module 30, and a processor 40, where:

[0039] The solid ultrasonic couplant 20 is a solid hydrogel and is fixed on the ultrasonic probe 10;

[0040] The electrical parameter measurement module 30 is respectively connected to both ends of the solid ultrasonic couplant 20 through connecting wires, and is used to measure the electrical parameters of the solid ultrasonic couplant during ultrasonic detection;

[0041] The processor 40 is used to generate an ultrasonic detection image based on the ultrasonic signal and electrical parameters collected by the ultrasonic probe.

[0042] It is understandable that the position of the target part in the imaging object is fixed. However, in the existing ultrasonic detection methods, when the ultrasonic detection physician applies different forces, the position and size of the detected target part vary. Taking a lesion in the human body as an example, the position of the lesion is fixed. When the ultrasonic detection physician applies different forces, the position and size of the detected lesion are different. To solve the above technical problems, the embodiments of the present invention combine acoustic signals and electrical signals to avoid the influence of externally applied forces on the ultrasonic detection results and achieve the normalization processing of ultrasonic signals. Specifically, a solid hydrogel rich in water, having stable mechanical properties and biocompatibility is used as a coupling agent during ultrasonic detection. By combining the piezoelectric effect property of the solid hydrogel itself and the characteristic that the ultrasonic waves emitted by the ultrasonic probe can penetrate the solid hydrogel to image the imaging part inside the imaging object, there is an obvious linear relationship between the position change of the imaging part inside the imaging object and the resistance change of the solid hydrogel. Using the above characteristics, the problem that the position information of the detected target object is different when the ultrasonic detection physician applies different forces can be effectively solved, thereby solving the problem that it is difficult to standardize ultrasonic detection in the prior art.

[0043] In this embodiment, before performing ultrasonic detection, a solid ultrasonic coupling agent of appropriate size is taken, the solid ultrasonic coupling agent is fixed on the ultrasonic probe, and the electrical parameter measurement module is connected to the solid ultrasonic coupling agent; during ultrasonic detection, the ultrasonic detection physician holds the ultrasonic probe to perform ultrasonic detection, and the ultrasonic probe receives the ultrasonic signal reflected by the emitted ultrasonic wave; the electrical parameter measurement module measures the electrical parameters of the solid ultrasonic coupling agent; the processor receives the ultrasonic signal collected by the ultrasonic probe and the electrical parameters measured by the electrical parameter measurement module, and generates an ultrasonic detection image based on the electrical parameters and the ultrasonic signal.

[0044] Optionally, the size of the solid ultrasonic coupling agent can be set according to the size of the ultrasonic probe. For example, a solid hydrogel with a length of 6 cm, a width of 2 cm, and a thickness of 3 mm is taken as the solid ultrasonic coupling agent. The electrical parameter measurement module can be a module capable of measuring the electrical parameters of the solid ultrasonic coupling agent, which is not limited herein. Among them, the electrical parameters of the solid ultrasonic coupling agent can be parameters such as voltage, current, and resistance of the solid ultrasonic coupling agent. Exemplarily, an LCR digital bridge can be used as the electrical parameter measurement module. Connect wires to both ends of the solid ultrasonic coupling agent, and the wires are connected to the LCR digital bridge to measure the electrical parameters of the solid ultrasonic coupling agent. Among them, L is inductance, R is resistance, and C is capacitance.

[0045] In an embodiment of the present invention, an ultrasonic detection image is generated based on ultrasonic signals and electrical parameters collected by an ultrasonic probe, including: performing normalization processing on the ultrasonic signals based on the electrical parameters to obtain target signals; generating an ultrasonic detection image based on the ultrasonic signals and the target signals. In this embodiment, taking advantage of the good linear relationship between the position change of the target object during ultrasonic detection and the change of the electrical parameters of the solid ultrasonic coupling agent, after obtaining the ultrasonic signals and the electrical parameters, the ultrasonic signals are normalized using the electrical parameters to obtain target signals, so that the target signals are not affected by the force applied by the ultrasonic detection physician during ultrasonic detection, thereby realizing the standardization of ultrasonic detection. After obtaining the target signals, an ultrasonic detection image is generated in combination with the ultrasonic signals collected by the ultrasonic probe, achieving the technical effect that the ultrasonic detection image generated based on the target signals is more accurate.

[0046] In one implementation, performing normalization processing on the ultrasonic signals based on the electrical parameters to obtain target signals includes: determining the resistance value of the solid hydrogel fusion agent according to the electrical parameters; determining the initial position information of the target object according to the ultrasonic signals; processing the initial position information based on the resistance value to obtain standard position information as the target signal. Specifically, when the solid hydrogel fusion agent is squeezed, there is a good linear relationship between the resistance parameters of the solid hydrogel fusion agent and the position information of the target object. Based on this, after obtaining the electrical parameters, the corresponding resistance value is determined; after obtaining the ultrasonic signals, the position information corresponding to the ultrasonic signals is determined as the initial position information; the initial position information is processed based on the resistance value to obtain standard position information to eliminate the influence of the externally applied force on the initial position information detected by ultrasonic. Among them, the initial position information can be the distance between the target object detected by the ultrasonic signals and the ultrasonic probe. Optionally, processing the initial position information based on the resistance value can be calculating the ratio between the resistance value and the initial position information, and normalizing the initial position information through the ratio to obtain the standard position information.

[0047] On the basis of the above solution, processing the initial position information based on the resistance value to obtain standard position information as the target signal includes: obtaining the resistance value change rate according to the resistance value, and obtaining the object position change rate according to the initial position information; processing the object position change rate through the resistance value change rate to obtain the standard position information. It can be understood that the calculation units of the resistance value and the initial position information are different. The calculation unit of the resistance value can be ohm (Ω), and the calculation unit of the initial position information can be centimeter / millimeter. Therefore, it is necessary to unify the units of the two to achieve accurate calculation of the position information. Optionally, the units of the two can be unified through the calculation of the change rate. The resistance value change rate is obtained according to the change of the resistance value over time, the object position change rate is obtained according to the change of the initial position information over time, and the initial position information is processed based on the resistance value change rate to obtain the standard position information.

[0048] Optionally, the object position change rate is processed through the resistance value change rate to obtain standard position information, including: using the ratio of the object position change rate to the resistance value change rate as the standard position information. Through experiments on solid hydrogels, it can be obtained that there is a good linear relationship between the resistance change rate of the solid hydrogel and the object position change rate during ultrasonic detection. Based on this, the ratio of the object position change rate to the resistance value change rate is used as the standard position information. Exemplarily, assuming the object position change rate is A and the resistance value change rate is B, then the standard position information C = B / A.

[0049] After obtaining the standard position information, the standard position information is used as the target signal, and combined with the ultrasonic signal to generate an ultrasonic detection image.

[0050] In this embodiment, the ultrasonic detection image includes an ultrasonic imaging diagram and parameter detection information. Among them, the ultrasonic imaging diagram is the ultrasonic image obtained by ultrasonic detection, and the parameter detection information can be the parameter information of the target object detected by ultrasonic detection, such as the position, size, etc. of the target object. Optionally, generating an ultrasonic detection image based on the ultrasonic signal and the target signal includes: generating an ultrasonic image according to the ultrasonic signal; determining the parameter display information of the target object according to the standard position information; combining the ultrasonic image and the parameter display information to obtain the ultrasonic detection image. Among them, the ultrasonic image can be generated in an existing manner, and the parameter display information is generated based on the standard position information obtained in the above embodiment. Assuming that the standard position information is the position coordinates of the target object, the size of the target object can be calculated according to the position coordinates of the target object, and the position coordinates and size are used as the parameter detection information. The ultrasonic detection image can be obtained by combining and splicing the ultrasonic image and the parameter detection information, such as splicing the parameter detection information on the right side of the ultrasonic image to obtain the ultrasonic detection image. The parameter detection information determined based on the standard position information is not affected by the external force applied during ultrasonic detection, ensuring the accuracy of the parameter detection information.

[0051] Embodiment Two

[0052] Figure 2 is a schematic flowchart of an ultrasonic detection method provided by Embodiment Two of the present invention. This embodiment is applicable to the situation during ultrasonic detection. This method can be executed by a processor in the ultrasonic detection system provided by any embodiment of the present invention. The processor can be configured to be implemented by an ultrasonic detection device, and the ultrasonic detection device can be implemented in the form of hardware and / or software. The ultrasonic detection device can be configured in an electronic device. As Figure 2 shown, the method includes:

[0053] S210. Receive the ultrasonic signal collected by the ultrasonic probe and the electrical parameter measured by the electrical parameter measurement module.

[0054] S220. Generate an ultrasonic detection image based on the ultrasonic signal and the electrical parameter.

[0055] Based on the above embodiments, optionally, generating an ultrasonic detection image based on the ultrasonic signal and the electrical parameter includes:

[0056] Perform normalization processing on the ultrasonic signal based on the electrical parameter to obtain a target signal;

[0057] Generate an ultrasonic detection image based on the ultrasonic signal and the target signal.

[0058] Based on the above embodiments, optionally, performing normalization processing on the ultrasonic signal based on the electrical parameter to obtain a target signal includes:

[0059] Determine the resistance value of the solid hydrogel fusion agent according to the electrical parameter;

[0060] Determine the initial position information of the target object according to the ultrasonic signal;

[0061] Process the initial position information based on the resistance value to obtain standard position information as the target signal.

[0062] Based on the above embodiments, optionally, processing the initial position information based on the resistance value to obtain standard position information as the target signal includes:

[0063] Obtain the resistance value change rate according to the resistance value, and obtain the object position change rate according to the initial position information;

[0064] Process the object position change rate through the resistance value change rate to obtain standard position information.

[0065] Based on the above embodiments, optionally, processing the object position change rate through the resistance value change rate to obtain standard position information includes:

[0066] Take the ratio of the object position change rate to the resistance value change rate as the standard position information.

[0067] Based on the above embodiments, optionally, generating an ultrasonic detection image based on the ultrasonic signal and the target signal includes:

[0068] Generate an ultrasonic image according to the ultrasonic signal;

[0069] Determine the parameter display information of the target object according to the standard position information;

[0070] Combine the ultrasonic image and the parameter display information to obtain the ultrasonic detection image.

[0071] The technical solution of this embodiment is to receive the ultrasonic signal collected by the ultrasonic probe and the electrical parameters measured by the electrical parameter measurement module; generate an ultrasonic detection image according to the ultrasonic signal and the electrical parameters, and standardize the ultrasonic signal by using the linear relationship between the piezoelectric effect characteristics of the solid hydrogel and the ultrasonic detection depth, realizing the standardization of the ultrasonic signal, so that the ultrasonic detection image obtained based on the ultrasonic signal is not affected by the force applied during the operation of the physician, and solving the technical problems of inconsistent ultrasonic imaging standards and inaccurate imaging results caused by inconsistent operation of physicians in the prior art.

[0072] The ultrasonic detection method provided by the embodiment of the present invention can be implemented by the processor in the ultrasonic detection system provided by any embodiment of the present invention. A more specific ultrasonic detection image generation method can be referred to the above embodiment and will not be elaborated here.

[0073] Embodiment III

[0074] Based on the above embodiment, this embodiment provides a preferred embodiment.

[0075] The ultrasonic detection method provided by this embodiment includes three parts: solid hydrogel preparation, hydrogel ultrasonic imaging, and ultrasonic imaging standardization.

[0076] I. Solid hydrogel preparation

[0077] ① Take an appropriate amount (such as 1 g) of gelatin and add an appropriate amount of deionized water (such as 9 g), and the concentration of gelatin is 10 wt%.

[0078] ② Use a magnetic stirrer, set the temperature to 50 - 60 °C, and continuously heat and stir for 20 - 30 minutes to dissolve it into a 10% gelatin aqueous solution.

[0079] ③ Place the copper block in a heat-insulating foam box, add an appropriate amount of liquid nitrogen to the foam box so that the liquid nitrogen level is flush with the copper block, place the mold containing the gelatin aqueous solution (such as a paper cup, glass bottle) on the copper block, close the foam box, and perform directional freezing for 0.5 - 1 hour.

[0080] ④ After the directional freezing is completed, demold the gelatin hydrogel, moderately thaw it, and then completely immerse it in a sufficient amount of 30 wt% ammonium sulfate aqueous solution (such as 30 g of ammonium sulfate dissolved in 70 g of deionized water), and change the soaked ammonium sulfate aqueous solution every 18 - 24 hours. According to the different sizes of the prepared gelatin hydrogel, the corresponding soaking time is 2 - 4 days, and the larger the size, the longer the soaking time.

[0081] Freezing can make the solid hydrogel form an ordered pore structure and have a good imaging effect.

[0082] ⑤The soaked gelatin hydrogel will shrink significantly, and it is cut into suitable shapes and sizes.

[0083] The gelatin aqueous solution will spontaneously solidify at room temperature. However, the mechanically stable property of the spontaneously solidified gelatin gel is poor. Whether it is demolded, stretched or extruded after solidification, it will break under a certain degree of load, which limits its scope of application and application scenarios. The gelatin hydrogel treated by directional freezing and soaking has higher mechanical strength and excellent properties in terms of stretchability, toughness and fatigue resistance.

[0084] In order to verify the mechanical stability of the solid hydrogel, a mechanical stability experiment was carried out on the solid hydrogel in this embodiment.

[0085] 1. Fracture toughness test

[0086] Specifically, the gelatin hydrogel that has been directionally frozen and soaked in ammonium persulfate solution is cut into appropriate sizes (thickness 1 mm, width 10 mm, and the initial length maintained during stretching between the clamps is 10 mm), denoted as specimen ①, and stretched at a speed of 3 mm / min until the sample is completely broken; take the same-sized gelatin hydrogel as above, and use a scalpel to make a 2-mm notch on the side of the hydrogel, denoted as specimen ②, and stretch the notched sample at a speed of 3 mm / min until it is completely broken.

[0087] Tough fracture energy G c The calculation formula is: where C is the initial length of the specimen, λ c is the strain corresponding to the complete fracture of specimen ②, and W is the strain energy calculated by integrating the stress-strain curve of specimen ① to λ c . The fracture toughness test results of the solid hydrogel can be obtained. Figure 3a It is a schematic diagram of the test results of the fracture toughness test of a solid hydrogel provided in Embodiment 3 of the present invention. Figure 3a In, the area under the curve to the left of the straight dotted line in specimen ① is the strain energy calculated by integrating the stress-strain curve of specimen ① to λ c . It can be seen from Figure 3a that specimen ① can be stretched to a strain of >300%, and the maximum stress during stretching reaches 1.29 MPa, proving its good stretchability. Table 1 is the statistics of the tough fracture energy of multiple tests. It can be seen from the table that the range of the tough fracture energy of the gelatin hydrogel used in the test is 67-80 kJ / m 2 , indicating its good toughness.

[0088] Table 1

[0089] W λc C(m) <![CDATA[Gc (J / m 2 )]]> Test 1 85314596.23 205.62％ 0.002 713953.9795 Test 2 87519272.16 209.63％ 0.002 725362.8778 Test 3 95162187.98 206.34％ 0.002 794979.7321 Test 4 76579813.75 186.75％ 0.002 672456.8666 Test 5 81004153.78 200.87％ 0.002 685857.0232

[0090] 2. Fatigue resistance test

[0091] (1) Take a gelatin hydrogel of appropriate size (thickness 1 mm, width 10 mm, keep its initial length between the clamps at 10 mm) and stretch the sample to the maximum strain λ at a stretching speed of 18 mm / min. max The stress-strain curves were recorded after 500 cycles of stretching. Figure 3b is a stress-strain curve diagram of a fatigue resistance test of a solid hydrogel provided in Example 3 of the present invention, Figure 3b The stress-strain curves after 500 cycles of stretching under different tensile strains are schematically shown, specifically, the stress-strain curves after 500 cycles of stretching to the maximum strain λ max The stress-strain curves corresponding to 1.2, 1.4, 1.6, 1.8, and 1.9.

[0092] (2) Take a gelatin hydrogel of appropriate size (thickness 1 mm, width 10 mm, keep its initial length stretched between the clamps at 10 mm), cut a 2 mm notch on the side of the hydrogel, and stretch the sample to the maximum strain λ at a stretching speed of 18 mm / min. max The tension is 1.2, 1.4, 1.6, 1.8, and 1.9, and 500 cycles of stretching are performed. The growth of the notch with the number of cycles during the test is recorded. Figure 3c is a schematic diagram of the gap growth of a solid hydrogel under tensile strain provided in Example 3 of the present invention, Figure 3c is the maximum strain λ in the 500th cycle max The stress-strain curves corresponding to 1.2, 1.4, 1.6, 1.8, and 1.9. Figure 3c The growth of the notch during 500 cycles under different tensile strains is schematically shown.

[0093] The calculation formula of fatigue fracture energy G is G = WH (λ max ), where W is the strain energy calculated by integrating the stress-strain curve for 500 cycles, and H is the initial length of the sample. With G as the abscissa and dc / dN as the ordinate, a scatter plot can be obtained. Figure 3d is a scatter plot of fatigue fracture energy of a solid hydrogel under stress provided by Example 3 of the present invention, such as Figure 3d As shown in Figure 2, when dc / dN is greater than 1, the corresponding fatigue fracture threshold is 664 J / m 2 , indicating that it has good fatigue resistance and can be reused without damage or breakage.

[0094] In summary, solid hydrogel has high mechanical strength and can be used as a coupling agent in ultrasonic testing.

[0095] 3. Piezoelectric effect of solid hydrogel

[0096] During the preparation process, gelatin hydrogel (i.e. solid hydrogel) is immersed in a sufficient amount of ammonium sulfate aqueous solution. During the immersion process, a large amount of ions penetrate into the network structure inside the gelatin hydrogel. When the gelatin hydrogel is squeezed or stretched, the internal network of the gel is deformed, and the ions in the network move violently, thereby changing the dielectric constant of the gelatin hydrogel and producing a piezoelectric effect.

[0097] Take a gelatin hydrogel of appropriate size (e.g., 6 cm long, 2 cm wide, and 3 mm thick), connect wires at both ends, connect the wires to the LCR digital bridge, and use an electronic universal testing machine to pressurize and release the gelatin hydrogel multiple times, and record the changes in the internal resistance of the gelatin hydrogel during the pressurization and release process, such as Figure 4 As shown, R0 represents the initial resistance value, and ΔR represents the difference in resistance change. Figure 3e Schematic diagram of the change in resistance of a solid hydrogel under stress provided by the third embodiment of the present invention. Figure 3e The resistance change of the solid hydrogel caused by stress can be seen in the figure.

[0098] 2. Hydrogel Ultrasound Imaging

[0099] In the embodiment of the present invention, the main raw material of gelatin hydrogel is gelatin, which is a substance extracted from animal skin and has properties similar to human skin. In addition, the ammonium sulfate solution used for immersion during the preparation process is a non-toxic and harmless substance. Therefore, gelatin hydrogel not only has very good biocompatibility, but also does not affect the effect of ultrasonic imaging. Figure 3f This is an ultrasound image obtained by ultrasound imaging using a solid hydrogel pad, provided in the third embodiment of the present invention, wherein the solid hydrogel pad is between the ultrasound probe and the artificial phantom. Figure 3f The middle arc position represents the "lesion" in the phantom. The "lesion" and its boundaries can be clearly seen, indicating that the solid hydrogel has the ability to assist in obtaining ultrasound imaging.

[0100] 3. Standardization of Ultrasound Imaging

[0101] The mechanical stability and piezoelectric properties of solid hydrogels have been confirmed, and they also have the function of assisting ultrasound imaging. Therefore, the embodiments of the present invention are designed to use such solid hydrogels in combination with their own electrical and acoustic properties to achieve ultrasound imaging standardization.

[0102] It should be noted that an experiment on ultrasonic detection was carried out based on a solid hydrogel in the embodiments of the present invention. Specifically, a small section of tungsten wire (diameter 0.03 mm) was embedded inside the solid hydrogel as a "lesion", and an ultrasonic probe was used to place on the gelatin hydrogel to perform ultrasonic imaging on the internal tungsten wire. Figure 3g It is a schematic diagram of an ultrasonic imaging provided in the third embodiment of the present invention. Figure 3g The tungsten wire serving as the lesion is within the dashed line; at the same time, by pressing the ultrasonic probe, the position change of the internal tungsten wire and the change of the resistance value of the hydrogel itself were recorded. The position change rate ΔD / D0 of the tungsten wire and the resistance value change rate ΔR / R0 of the hydrogel during the test were used as the horizontal and vertical coordinates respectively, and fitting curves were taken for each data point, and the relationship between the position change rate of the tungsten wire and the resistance value change rate of the hydrogel could be obtained. Figure 3h It is a schematic diagram of the linear relationship between the position change rate of the tungsten wire and the resistance value change rate of the hydrogel provided in the third embodiment of the present invention. As Figure 3h shown, after calculation, the R-square is 0.9924, indicating that there is a good linear relationship between the two. Applying this method and conclusion to ultrasonic detection, combining the ultrasonic imaging situation with the change relationship of electrical signals, can realize the standardization of ultrasonic imaging, which will help the examining doctor to more quickly and accurately judge the morphology and position of structures such as glands and lesions, and improve the accuracy of ultrasonic detection.

[0103] The technical solution of this embodiment combines the acoustic signal and the electrical signal, and uses the electrical signal of the solid hydrogel to standardize the ultrasonic signal, so that the ultrasonic detection result is not affected by the externally applied force, and the accuracy of the ultrasonic detection result is improved.

[0104] Embodiment 4

[0105] Figure 4 It is a schematic structural diagram of an ultrasonic detection device provided in the fourth embodiment of the present invention. As Figure 4 shown, the device includes a signal receiving module 410 and an image generating module 420, wherein:

[0106] The signal receiving module 410 is used to receive the ultrasonic signal collected by the ultrasonic probe and the electrical parameters measured by the electrical parameter measurement module;

[0107] The image generating module 420 is used to generate an ultrasonic detection image according to the ultrasonic signal and the electrical parameters.

[0108] In the technical solution of this embodiment, the signal receiving module receives the ultrasonic signal collected by the ultrasonic probe and the electrical parameters measured by the electrical parameter measurement module; the image generation module generates an ultrasonic detection image based on the ultrasonic signal and the electrical parameters. By using the linear relationship between the piezoelectric effect characteristics of the solid hydrogel and the ultrasonic detection depth to standardize the ultrasonic signal, the standardization of the ultrasonic signal is achieved, so that the ultrasonic detection image obtained based on the ultrasonic signal is not affected by the force applied during the operation of the physician, and the technical problems of inconsistent ultrasonic imaging standards and inaccurate imaging results caused by inconsistent physician operations in the prior art are solved.

[0109] Based on the above embodiment, optionally, the image generation module 420 includes:

[0110] A target signal determination unit, configured to standardize the ultrasonic signal based on the electrical parameters to obtain a target signal;

[0111] A detection image generation unit, configured to generate an ultrasonic detection image based on the ultrasonic signal and the target signal.

[0112] Based on the above embodiment, optionally, the target signal determination unit is specifically configured to:

[0113] Determine the resistance value of the solid hydrogel fusion agent according to the electrical parameters;

[0114] Determine the initial position information of the target object according to the ultrasonic signal;

[0115] Process the initial position information based on the resistance value to obtain the standard position information as the target signal.

[0116] Based on the above embodiment, optionally, the target signal determination unit is specifically configured to:

[0117] Obtain the resistance value change rate according to the resistance value, and obtain the object position change rate according to the initial position information;

[0118] Process the object position change rate through the resistance value change rate to obtain the standard position information.

[0119] Based on the above embodiment, optionally, the target signal determination unit is specifically configured to:

[0120] Use the ratio of the object position change rate to the resistance value change rate as the standard position information.

[0121] Based on the above embodiment, optionally, the detection image generation unit is specifically configured to:

[0122] Generate an ultrasonic image according to the ultrasonic signal;

[0123] Determine the parameter display information of the target object according to the standard position information;

[0124] Combine the ultrasonic image and the parameter display information to obtain an ultrasonic detection image.

[0125] The ultrasonic detection device provided by the embodiment of the present invention can execute the ultrasonic detection method provided by any embodiment of the present invention, and has the corresponding functional modules and beneficial effects for executing the method.

[0126] Embodiment Five

[0127] Figure 5 It is a schematic structural diagram of an electronic device provided by Embodiment Five of the present invention. The electronic device 10 is intended to represent various forms of digital computers, such as, laptop computers, desktop computers, workstations, personal digital assistants, servers, blade servers, mainframe computers, and other suitable computers. The electronic device can also represent various forms of mobile devices, such as, personal digital processors, cellular phones, smart phones, wearable devices (such as helmets, glasses, watches, etc.) and other similar computing devices. The components shown herein, their connections and relationships, and their functions are merely illustrative and are not intended to limit the implementation of the present invention described and / or claimed herein.

[0128] As Figure 5 shown, the electronic device 10 includes at least one processor 11, and a memory communicatively connected to the at least one processor 11, such as a read-only memory (ROM) 12, a random access memory (RAM) 13, etc. Among them, the memory stores a computer program executable by the at least one processor. The processor 11 can execute various appropriate actions and processes according to the computer program stored in the read-only memory (ROM) 12 or the computer program loaded from the storage unit 18 into the random access memory (RAM) 13. In the RAM 13, various programs and data required for the operation of the electronic device 10 can also be stored. The processor 11, the ROM 12, and the RAM 13 are connected to each other through a bus 14. The input / output (I / O) interface 15 is also connected to the bus 14.

[0129] Multiple components in the electronic device 10 are connected to the I / O interface 15, including: an input unit 16, such as a keyboard, a mouse, etc.; an output unit 17, such as various types of displays, speakers, etc.; a storage unit 18, such as a magnetic disk, an optical disc, etc.; and a communication unit 19, such as a network card, a modem, a wireless communication transceiver, etc. The communication unit 19 allows the electronic device 10 to exchange information / data with other devices through a computer network such as the Internet and / or various telecommunication networks.

[0130] The processor 11 can be various general-purpose and / or special-purpose processing components with processing and computing capabilities. Some examples of the processor 11 include, but are not limited to, a central processing unit (CPU), a graphics processing unit (GPU), various dedicated artificial intelligence (AI) computing chips, various processors running machine learning model algorithms, a digital signal processor (DSP), and any suitable processor, controller, microcontroller, etc. The processor 11 executes the various methods and processes described above, such as the ultrasonic detection method.

[0131] In some embodiments, the ultrasonic detection method can be implemented as a computer program tangibly embodied in a computer-readable storage medium, such as the storage unit 18. In some embodiments, part or all of the computer program can be loaded and / or installed onto the electronic device 10 via the ROM 12 and / or the communication unit 19. When the computer program is loaded into the RAM 13 and executed by the processor 11, one or more steps of the ultrasonic detection method described above can be executed. Alternatively, in other embodiments, the processor 11 can be configured to execute the ultrasonic detection method by any other suitable means (e.g., by means of firmware).

[0132] Various embodiments of the systems and techniques described above in this document can be implemented in digital electronic circuit systems, integrated circuit systems, field-programmable gate arrays (FPGAs), application-specific integrated circuits (ASICs), application-specific standard products (ASSPs), systems-on-chip (SOCs), complex programmable logic devices (CPLDs), computer hardware, firmware, software, and / or combinations thereof. These various embodiments can include: being implemented in one or more computer programs that can be executed and / or interpreted on a programmable system including at least one programmable processor, which can be a dedicated or general-purpose programmable processor that can receive data and instructions from a storage system, at least one input device, and at least one output device, and transmit the data and instructions to the storage system, the at least one input device, and the at least one output device.

[0133] The computer program for implementing the ultrasonic detection method of the present invention can be written in any combination of one or more programming languages. These computer programs can be provided to the processor of a general-purpose computer, a special-purpose computer, or other programmable data processing device, such that when the computer program is executed by the processor, the functions / operations specified in the flowchart and / or block diagram are implemented. The computer program can be executed entirely on the machine, partially on the machine, as an independent software package partially on the machine and partially on a remote machine, or entirely on a remote machine or server.

[0134] Embodiment Six

[0135] Embodiment 6 of the present invention further provides a computer-readable storage medium storing computer instructions for causing a processor to execute an ultrasonic detection method, the method comprising:

[0136] Receiving ultrasonic signals collected by an ultrasonic probe and electrical parameters measured by the electrical parameter measurement module;

[0137] Generating an ultrasonic detection image based on the ultrasonic signals and the electrical parameters.

[0138] In the context of the present invention, a computer-readable storage medium may be a tangible medium that can contain or store a computer program for use by or in connection with an instruction execution system, apparatus, or device. A computer-readable storage medium may include, but is not limited to, electronic, magnetic, optical, electromagnetic, infrared, or semiconductor systems, apparatus, or devices, or any suitable combination of the foregoing. Alternatively, a computer-readable storage medium may be a machine-readable signal medium. More specific examples of machine-readable storage media would include electrical connections based on one or more wires, a portable computer diskette, a hard disk, a random access memory (RAM), a read-only memory (ROM), an erasable programmable read-only memory (EPROM or Flash memory), an optical fiber, a portable compact disc read-only memory (CD-ROM), an optical storage device, a magnetic storage device, or any suitable combination of the foregoing.

[0139] To provide interaction with a user, the systems and techniques described herein may be implemented on an electronic device having: a display device (e.g., a CRT (cathode ray tube) or LCD (liquid crystal display) monitor) for displaying information to the user; and a keyboard and a pointing device (e.g., a mouse or a trackball) by which the user can provide input to the electronic device. Other kinds of devices may also be used to provide interaction with the user; for example, the feedback provided to the user may be any form of sensory feedback (e.g., visual feedback, auditory feedback, or tactile feedback); and input from the user may be received in any form (including acoustic input, voice input, or tactile input).

[0140] The systems and techniques described herein can be implemented in a computing system including backend components (e.g., as a data server), or a computing system including middleware components (e.g., an application server), or a computing system including frontend components (e.g., a user computer having a graphical user interface or a web browser through which a user can interact with an implementation of the systems and techniques described herein), or a computing system including any combination of such backend components, middleware components, or frontend components. The components of the system can be interconnected to each other by digital data communication in any form or medium (e.g., a communication network). Examples of communication networks include: local area network (LAN), wide area network (WAN), blockchain network, and the Internet.

[0141] A computing system can include a client and a server. The client and the server are generally remote from each other and typically interact through a communication network. The client-server relationship is created by computer programs running on respective computers and having a client-server relationship with each other. The server can be a cloud server, also known as a cloud computing server or a cloud host, which is a host product in the cloud computing service system, solving the defects of difficult management and weak business scalability existing in traditional physical hosts and VPS services.

[0142] It should be understood that various forms of the processes shown above can be used, with steps reordered, added, or deleted. For example, the steps recited in the present invention can be executed in parallel, sequentially, or in a different order, as long as the desired results of the technical solution of the present invention can be achieved, and no limitation is imposed herein.

[0143] The above specific embodiments do not constitute a limitation on the protection scope of the present invention. Those skilled in the art should understand that various modifications, combinations, sub-combinations, and substitutions can be made according to design requirements and other factors. Any modifications, equivalent substitutions, and improvements made within the spirit and principles of the present invention shall be included within the protection scope of the present invention.

Claims

1. An ultrasonic detection system, characterized in that, It includes an ultrasonic probe, a solid ultrasonic coupling agent, an electrical parameter measurement module, and a processor, where: The solid ultrasonic coupling agent is a solid hydrogel and is fixed on the ultrasonic probe; The electrical parameter measurement module is respectively connected to both ends of the solid ultrasonic coupling agent through connecting wires and is used to measure the electrical parameters of the solid ultrasonic coupling agent during ultrasonic detection; The processor is used to generate an ultrasonic detection image based on the ultrasonic signal collected by the ultrasonic probe and the electrical parameters; Among them, generating the ultrasonic detection image based on the ultrasonic signal collected by the ultrasonic probe and the electrical parameters includes: Performing normalization processing on the ultrasonic signal based on the electrical parameters to obtain a target signal; Generating the ultrasonic detection image based on the ultrasonic signal and the target signal; Among them, performing normalization processing on the ultrasonic signal based on the electrical parameters to obtain a target signal includes: Determining the resistance value of the solid hydrogel according to the electrical parameters; Determining the initial position information of the target object according to the ultrasonic signal; Processing the initial position information based on the resistance value to obtain standard position information as the target signal; Among them, processing the initial position information based on the resistance value to obtain standard position information as the target signal includes: Obtaining a resistance value change rate according to the resistance value and obtaining an object position change rate according to the initial position information; Processing the object position change rate through the resistance value change rate to obtain the standard position information.

2. The ultrasonic detection system according to claim 1, wherein The processing the object position change rate through the resistance value change rate to obtain the standard position information includes: Taking the ratio of the object position change rate to the resistance value change rate as the standard position information.

3. The ultrasonic detection system according to claim 1, characterized in that, Generating the ultrasonic detection image based on the ultrasonic signal and the target signal includes: Generating an ultrasonic image according to the ultrasonic signal; Determining parameter display information of the target object according to the standard position information; Combining the ultrasonic image and the parameter display information to obtain the ultrasonic detection image.

4. An ultrasonic detection method, characterized in that, The ultrasonic detection method includes: Receiving the ultrasonic signal collected by the ultrasonic probe and the electrical parameters measured by the electrical parameter measurement module; among them, the solid ultrasonic coupling agent is a solid hydrogel and is fixed on the ultrasonic probe; the electrical parameter measurement module is respectively connected to both ends of the solid ultrasonic coupling agent through connecting wires and is used to measure the electrical parameters of the solid ultrasonic coupling agent during ultrasonic detection; Generating an ultrasonic detection image according to the ultrasonic signal and the electrical parameters; Among them, generating the ultrasonic detection image according to the ultrasonic signal and the electrical parameters includes: Performing normalization processing on the ultrasonic signal based on the electrical parameters to obtain a target signal; Generating the ultrasonic detection image based on the ultrasonic signal and the target signal; Among them, performing normalization processing on the ultrasonic signal based on the electrical parameters to obtain a target signal includes: Determining the resistance value of the solid hydrogel according to the electrical parameters; Determining the initial position information of the target object according to the ultrasonic signal; Process the initial position information based on the resistance value to obtain standard position information as the target signal; Among them, the process of processing the initial position information based on the resistance value to obtain standard position information as the target signal includes: Obtain the resistance value change rate according to the resistance value, and obtain the object position change rate according to the initial position information; Process the object position change rate through the resistance value change rate to obtain the standard position information.

5. An ultrasonic detection device, characterized in that, The ultrasonic detection device includes: A signal receiving module, configured to receive the ultrasonic signal collected by the ultrasonic probe and the electrical parameters measured by the electrical parameter measurement module; among them, the solid ultrasonic couplant is a solid hydrogel and is fixed on the ultrasonic probe; the electrical parameter measurement module is respectively connected to both ends of the solid ultrasonic couplant through a connecting wire for measuring the electrical parameters of the solid ultrasonic couplant during ultrasonic detection; An image generation module, configured to generate an ultrasonic detection image according to the ultrasonic signal and the electrical parameters; Among them, the image generation module includes: A target signal determination unit, configured to perform standardization processing on the ultrasonic signal based on the electrical parameters to obtain a target signal; A detection image generation unit, configured to generate the ultrasonic detection image based on the ultrasonic signal and the target signal; Among them, the target signal determination unit is specifically configured to: Determine the resistance value of the solid hydrogel according to the electrical parameters; Determine the initial position information of the target object according to the ultrasonic signal; Process the initial position information based on the resistance value to obtain standard position information as the target signal; Among them, the process of processing the initial position information based on the resistance value to obtain standard position information as the target signal includes: Obtain the resistance value change rate according to the resistance value, and obtain the object position change rate according to the initial position information; Process the object position change rate through the resistance value change rate to obtain the standard position information.

6. An electronic device, characterized in that, The electronic device includes: At least one processor; and A memory communicatively connected to the at least one processor; among them, The memory stores a computer program executable by the at least one processor, and the computer program is executed by the at least one processor so that the at least one processor can execute the ultrasonic detection method according to claim 4.

7. A computer-readable storage medium, characterized in that, The computer-readable storage medium stores computer instructions, and when the processor executes the computer instructions, the ultrasonic detection method according to claim 4 is implemented.

Images