Pre-processing device

By designing an automated pre-treatment device, cutting the swab tube and knocking away the waste, squeezing the outer wall of the swab tube to mix the sample and reagent, the problems of time-consuming, labor-intensive and polluting traditional pre-treatment are solved, and fast and convenient sample pre-treatment is achieved.

CN114964942BActive Publication Date: 2025-09-26ZHUHAI LITUO DEV +1
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Patent Information

Application Number
CN202210393142.3
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2022-04-15
Publication Date
2025-09-26
Estimated Expiration
2042-04-15

AI Technical Summary

Technical Problem

Traditional sample pre-processing methods are time-consuming, labor-intensive, and prone to operational errors, and manual processing can pollute the environment.

Method used

A pretreatment device was designed, which included a tube cutting mechanism and a tube squeezing mechanism. The incision was formed by cutting the upper end of the swab tube, and the waste was knocked away by a pusher plate. The outer wall of the swab tube was squeezed to mix the sample and reagent. Combined with the code scanning and dilution mechanism, automated processing was achieved.

Benefits of technology

It achieves fast and convenient sample pre-processing, reduces operational errors, improves processing efficiency, and reduces the risk of environmental pollution.

✦ Generated by Eureka AI based on patent content.

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Abstract

The present invention discloses a pre-treatment device, including a tube cutting mechanism and a tube squeezing mechanism. The tube cutting mechanism includes an upper cutter and a lower cutter that move relative to each other. The upper cutter and the lower cutter move toward each other to cut the upper end of the swab tube, so that the upper end of the swab tube is formed with an incision for adding reagents; the tube squeezing mechanism squeezes the swab tube, causing the swab tube to elastically deform, so as to mix the sample and reagent in the swab tube. The pre-treatment device of the present invention uses the tube cutting mechanism to cut the swab tube to form an incision, which is faster and more convenient than the method of pulling out or piercing the tube plug in traditional pre-treatment devices, and is convenient for the equipment to perform batch processing; and by utilizing the characteristic that the swab tube body is a soft tube, by squeezing the outer wall of the tube body, the reagent in the tube is fully mixed with the sample, without shaking the tube body, which is more convenient and quick.
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Description

Technical Field

[0001] The present invention belongs to the field of medical detection, and in particular relates to a pre-processing device. Background Art

[0002] The complete sample analysis process, from sampling to writing an analytical report, can be roughly divided into four steps: sample collection, sample pretreatment, analytical testing, and data processing and reporting. The exploration and research of various new technologies and methods has become a key topic and development direction in contemporary analytical chemistry.

[0003] However, sample pretreatment is traditionally manual, requiring manual recording of sample information, addition of diluents, and placement of test tubes into analytical instruments. This approach is not only time-consuming and labor-intensive, but also prone to errors due to different operators and repeated sample transfers. Furthermore, the use of large amounts of organic solvents during pretreatment can pollute the environment. Summary of the Invention

[0004] The present invention provides a pre-treatment device to solve the technical problems mentioned in the background art that manual treatment is time-consuming, labor-intensive and prone to pollution.

[0005] To achieve the above objectives, the specific technical solutions of the pre-processing device of the present invention are as follows:

[0006] A pretreatment device includes a tube cutting mechanism and a tube squeezing mechanism. The tube cutting mechanism includes an upper cutter and a lower cutter that move relatively. The upper cutter and the lower cutter move toward each other to cut off the upper end of the swab tube, so that an incision for adding reagents is formed on the upper end of the swab tube; the tube squeezing mechanism squeezes the swab tube, causing the swab tube to elastically deform, so as to mix the sample and reagent in the swab tube.

[0007] Furthermore, a swingable push plate is provided on the upper side of the cutter, and the lower end of the push plate hits the upper end of the swab tube to knock away the waste material cut off from the upper end of the swab tube.

[0008] Furthermore, the cutter outer cover is provided with a material guide cover, and the waste materials knocked away by the push plate slide along the inner cavity of the material guide cover.

[0009] Furthermore, the material guide cover includes a relatively movable enclosure and a guide plate, and an opening is formed on the adjacent side of the enclosure and the guide plate; as the cutter cuts the tube, the enclosure and the guide plate are closed and the cover is arranged outside the swab tube; as the upper cutter and the lower cutter separate, the enclosure and the guide plate separate to allow the swab tube to move between the enclosure and the guide plate.

[0010] Furthermore, the middle part of the push plate is rotatably connected to the enclosure, and a first elastic member is provided at one end of the push plate away from the cutter to pull the push plate, and the push plate swings close to the cutter to knock away the waste.

[0011] Furthermore, the enclosure is provided with a rotating shaft, and the push plate is provided with a straight hole arranged along the length direction, and the straight hole is for the rotating shaft to pass through; the enclosure is slidably connected to a guide shaft, and the end of the guide shaft is hinged to the lower end of the push plate, and the guide shaft limits the forward direction of the lower end of the push plate.

[0012] Furthermore, a rotatable driving wheel is provided on the enclosure, and a rotatable driven wheel is provided on the guide plate; the enclosure and the guide plate move toward each other, so that the driving wheel and the driven wheel respectively abut against both sides of the swab tube, and the driving wheel drives the swab tube to rotate to cooperate with the camera to scan the code on the swab tube.

[0013] Furthermore, the tube squeezing mechanism includes a movable positioning column, and a first tube squeezing head and a second tube squeezing head that are movable relative to each other; the positioning column squeezes the swab tube before the tube squeezing head to position the swab tube; the two tube squeezing heads move relative to each other, squeezing the outer wall of the swab tube to mix the sample and reagent inside the tube body.

[0014] Furthermore, the tube squeezing head is slidably connected to the slide seat; a buffer is provided between the tube squeezing head and the slide seat, and the buffer buffers the impact of the contact between the tube squeezing head and the swab tube.

[0015] Furthermore, the swab tube is placed on a test tube rack; guard plates are formed on both sides of the test tube rack so that the test tube rack can move between the two guard plates; the tube squeezing head penetrates the guard plates and the test tube rack and abuts against the outer wall of the swab tube.

[0016] The pre-treatment device of the present invention has the following advantages:

[0017] 1. The swab tube is cut into an incision by the tube cutting mechanism. Compared with the traditional pre-treatment device which requires pulling out or piercing the tube plug, it is faster and more convenient, and is also convenient for batch processing.

[0018] 2. Use the swinging push plate to knock away the waste sheared from the swab tube, and quickly recover the waste. Moreover, the guide shaft ensures that the lower end of the push plate moves in a straight line, ensuring the striking position of the push plate on the test tube and ensuring that the test tube is knocked away;

[0019] 3. Since the swab tube is a soft tube, the reagent and sample in the tube can be fully mixed by squeezing the outer wall of the tube without shaking the tube, which is more convenient and quick;

[0020] 4. The setting position of the tube pressing block cooperates with the guard plate and the test tube rack, and is assisted by positioning columns to ensure the positioning effect. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Figure 1 Schematic diagram of the test tube rack and swab tube of the present invention;

[0022] Figure 2 is a cross-sectional view of a test tube rack and a swab tube of the present invention;

[0023] Figure 3 This is a structural diagram of the code scanning mechanism and pipe cutting mechanism of the upstream part of the pre-processing device of the present invention;

[0024] Figure 4 This is a schematic structural diagram of the dilution mechanism and the pipe squeezing mechanism in the downstream portion of the pre-treatment device of the present invention;

[0025] Figure 5 It is a schematic structural diagram of the mobile device of the present invention;

[0026] Figure 6 Schematic diagram of the structure of the pipe cutting mechanism of the present invention (the material guide cover is hidden);

[0027] Figure 7 Schematic diagram of the structure of the pipe cutting mechanism of the present invention (shown by the material guide cover);

[0028] Figure 8 is a cross-sectional view of the pipe cutting mechanism of the present invention;

[0029] Figure 9 This is a cross-sectional view of the code scanning mechanism of the present invention;

[0030] Figure 10 for Figure 9 A magnified view of part A;

[0031] Figure 11 This is a schematic diagram of the installation position of the tube extrusion mechanism of the present invention;

[0032] Figure 12 Schematic diagram of the structure of the tube extrusion mechanism of the present invention;

[0033] Figure 13 for Figure 12 A magnified view of part B;

[0034] Figure 14 for Figure 12 Enlarged view of part C.

[0035] Description of the marks in the figure:

[0036] 1. Test tube rack; 11. Base; 12. Side wall; 13. Slot; 14. Through slot; 15. Connecting part; 16. Side edge; 2. Swab tube; 21. Tube body; 22. Tube plug; 23. Swab; 3. Workbench; 31. First slide; 32. Second slide; 33. Third slide; 34. Guard plate; 341. Avoidance; 35. Limiting wheel; 4. Moving device; 41. Transmission belt; 42. Driving slider; 43. Claw; 5. Column; 51. First fixed plate; 52. Second fixed plate; 6. Tube cutting mechanism; 61. First slide; 611. Upper cutter; 612. Enclosure; 613. Rotating shaft; 62. Second slide; 621. Lower cutter; 622. Guide plate; 6221. Discharge port; 6222. Material blocking part ;63. First lead screw;631. Tube cutting motor;64. Push plate;641. Slotted hole;65. First spring;66. Guide shaft;67. Return column;7. Scanning mechanism;71. Mounting seat;72. Adjusting plate;721. Driven wheel;722. Screw;73. Second spring;74. Driving wheel;741. Scanning motor;8. Filling needle;9. Tube squeezing mechanism;91. First slide;911. First tube squeezing head;92. Second slide;921. Second tube squeezing head;93. Second lead screw;931. Tube squeezing motor;94. Buffer spring;95. Boss;951. Soft pressure block;952. Concave surface;96. Nut;961. Buffer pad;97. Positioning column;971. Conical pressure block;98. Compression spring. DETAILED DESCRIPTION

[0037] In order to better understand the purpose, structure and function of the present invention, a pre-treatment device of the present invention is further described in detail below with reference to the accompanying drawings.

[0038] The pre-processing device of the present invention is as follows Figure 3 and Figure 4 As shown, the apparatus comprises a body and a test tube rack 1. A swab tube 2 is placed on the test tube rack 1. A moving device 4 is provided on the body. The moving device 4 drives the test tube rack 1 and the swab tube 2 to move on the body, so that the swab tube 2 passes through the scanning, cutting, diluting and squeezing mechanisms in sequence to complete the pre-treatment.

[0039] Among them, Figure 1 and Figure 2 As shown, the swab tube 2 includes a tube body 21 and a tube plug 22. The tube plug 22 blocks the tube body 21. The tube plug 22 is fixedly connected to a swab 23. The end of the swab 23 is dipped with a sample and inserted into the tube body 21. The tube body 21 is a soft tube, so that the sample on the swab 23 can be mixed by squeezing the outer wall of the tube body 21, and then the reagent in the tube body 21 can be added to complete the pretreatment.

[0040] The test tube rack 1 includes a base 11 with opposing sidewalls 12. A slot 13 for inserting a swab tube 2 is formed between adjacent sidewalls 12. Through slots 14 are formed on the front and back sides of the test tube rack 1. Through slots 14 communicate with slots 13 to expose the swab tube 2, facilitating subsequent squeezing and mixing of the tube body 21. Furthermore, a connecting portion 15 spans the tops of the sidewalls 12 to connect them and ensure the strength of the test tube rack 1.

[0041] In order to drive the test tube rack 1 to move, a workbench 3 is provided on the machine body, and a moving device 4 is provided on the lower side of the workbench 3 to drive the test tube rack 1 to slide on the workbench 3. In order to save space occupied by the pre-treatment device, a first slide 31, a second slide 32 and a third slide 33 connected in sequence are provided on the workbench 3. The first slide 31 and the third slide 33 are arranged opposite to each other and have opposite flow directions. The second slide 32 extends from the end of the first slide 31 to the starting end of the third slide 33, and the second slide 32 is provided with the scanning, tube cutting, dilution and tube squeezing mechanisms in sequence. First, the test tube rack 1 enters the second slide 32 from the first slide 31; then, in the second slide 32, it passes through the scanning, tube cutting, dilution and tube squeezing stations to complete the pre-treatment; finally, the swab tube 2 that has completed the pre-treatment leaves the pre-treatment device from the third slide 33. The slide is thus arranged in a U-shape to ensure that the swab tube 2 enters and exits from one side of the machine body.

[0042] To prevent the test tube rack 1 from detaching from the slide, guard plates 34 are formed on both sides of the slide. These guard plates 34 are positioned on either side of the test tube rack 1 to ensure that the test tube rack 1 is positioned within the chute formed by the slide and guard plates 34. Furthermore, since operations at various stations on the second slide 32 may cause the test tube rack 1 to detach from the slide, the second slide 32 can be further provided with a limiting structure. For example, a limiting wheel 35 is rotatably connected to the guard plate 34, while a protruding side edge 16 is formed on one side of the base 11 of the test tube rack 1. The side edge 16 is inserted into the gap between the limiting wheel 35 and the slide, thereby further limiting the position of the test tube rack 1.

[0043] Considering the difficulty of setting up, each slide is provided with a corresponding moving device 4. Figure 5 As shown, the moving device 4 generally comprises a transmission belt 41 and a driving slider 42. The driving slider 42 is slidably connected to the body and fixed to the transmission belt 41. A hook 43 is fixed to the driving slider 42. The hook 43 extends from the lower side of the workbench 3 to the surface of the workbench 3 to abut against the base 11 of the test tube rack 1. As the transmission belt 41 moves, the driving slider 42 moves, and the test tube rack 1 is driven to slide along the slideway through the hook 43.

[0044] Combine Figure 6-Figure 8As shown, a column 5 is fixed to one side of the workbench 3 on the machine body. A first fixed plate 51 extending to the workbench 3 is fixed to the column 5. A first slide 61 and a second slide 62 are slidably connected to the first fixed plate 51 via guide rails. An upper cutter 611 is fixed to the first slide 61, and a lower cutter 621 is fixed to the second slide 62. The upper cutter 611 and the lower cutter 621 are arranged opposite each other and have blades formed on adjacent sides. As the two slides move toward each other, the upper cutter 611 and the lower cutter 621 approach and intersect with each other, cutting the upper end of the swab tube 2, allowing the swab 23 to fall into the tube body 21. An incision is also formed at the upper end of the tube body 21 to facilitate the addition of diluent and subsequent sampling. As the two slides move away from each other, the upper cutter 611 and the lower cutter 621 separate, and the swab tube 2 continues to advance along the second slide 32 and enter the subsequent mechanism. In this way, the swab tube 2 can be opened more quickly by cutting.

[0045] In order to drive the two slides to move, a rotatable first lead screw 63 is mounted on the first fixed plate 51. The two ends of the first lead screw 63 are respectively provided with threaded portions with opposite rotation directions. The first slide 61 and the second slide 62 are respectively threadedly connected to the two threaded portions, so that the first lead screw 63 is driven to rotate by the tube cutting motor 631, so that the first slide 61 and the second slide 62 are moved away from or towards each other, thereby causing the upper cutter 611 and the lower cutter 621 to move relative to each other. The lead screw of the present application can be a double-headed screw that is integrally arranged, or it can be made of two screws with opposite rotation directions spliced ​​together by a coupling. In addition, in addition to using a lead screw to drive the slide, a drive mechanism such as magnetic levitation, compression cylinder, etc. can also be used.

[0046] To separate the upper end of the swab tube 2 as waste during the tube cutting process, a swingable pusher plate 64 is provided on the upper side of the cutter. The pusher plate 64 swings, causing the lower end of the pusher plate 64 to strike the upper end of the swab tube 2, that is, the upper end of the tube body 21 and the tube plug 22, thereby separating the waste from the lower end of the tube body 21 and completing the separation of the swab tube 2. In addition, the cutter housing is provided with a guide shield, and the waste ejected by the pusher plate 64 slides along the inner cavity of the guide shield to achieve waste limitation and recovery, preventing the waste from flying out and injuring personnel.

[0047] Specifically, the material guide cover includes a surrounding plate 612 and a guide plate 622. The surrounding plate 612 is fixed on the first slide 61, and the guide plate 622 is fixed on the second slide 62. An opening is formed on the adjacent side of the surrounding plate 612 and the guide plate 622, so that as the cutter cuts the tube, the surrounding plate 612 and the guide plate 622 are closed and the cover is arranged outside the swab tube 2; as the upper cutter 611 and the lower cutter 621 separate, the surrounding plate 612 and the guide plate 622 separate to allow the swab tube 2 to move between the surrounding plate 612 and the guide plate 622.

[0048] The pusher plate 64 is mounted on the enclosure 612. To allow the pusher plate 64 to swing on the enclosure 612, the middle portion of the pusher plate 64 is pivotally connected to the enclosure 612. A first spring 65, serving as a first elastic member, is mounted at the upper end of the pusher plate 64. One end of the first spring 65 is attached to the pusher plate 64, and the other end is attached to the top of the column 5. As the cutter cuts the tube, the first spring 65 pulls on the upper end of the pusher plate 64, causing it to swing. This causes the lower end of the pusher plate 64 to knock waste material away, ejecting the removed upper end of the swab tube 2. Specifically, the pusher plate 64 can be pivotally connected in two ways.

[0049] The first method involves installing a rotating shaft 613 on the enclosure 612 and a shaft hole on the pusher plate 64 for the shaft 613 to pass through. This allows the pusher plate 64 to be rotatably connected to the enclosure 612, a fixed-axis connection. However, this method cannot guarantee that the pusher plate 64 will strike the swab tube 2 if the swab tube 2 is of an uncertain model, and the path of the waste material being ejected is unclear, making it a less preferred option.

[0050] The second method is to use a plate 612 with a rotating shaft 613 and a push plate 64 with a slotted hole 641 extending along its length for the rotation shaft 613 to pass through. A guide shaft 66 is slidably connected to the lower side of the rotation shaft 613 on the plate 612. The guide shaft 66 is arranged parallel to the cutter and perpendicular to the rotation shaft 613. The distal end of the guide shaft 66 is hinged to the lower end of the push plate 64. The guide shaft 66 limits the forward direction of the lower end of the push plate 64, ensuring that the lower end of the push plate 64 strikes the upper end of the swab tube 2, knocking away the waste material cut off from the upper end of the swab tube 2 and separating the upper and lower ends of the swab tube 2. Because the second method of connecting the push plate 64 ensures a guaranteed knockback path, waste material recovery is facilitated. In addition, the straight hole 641 can also be set on the enclosure 612, and the rotating shaft 613 is fixed on the push plate 64. By swapping the setting relationship between the straight hole 641 and the rotating shaft 613, the push plate 64 can still be swung by the movable shaft.

[0051] In order to ensure that the swinging push plate 64 also returns to its position synchronously when the cutter returns to its position, a return column 67 is fixed to the column 5. The end of the return column 67 is used to abut against the upper end of the push plate 64, so that the push plate 64 swings in the opposite direction to return to its original position. In addition, the return column 67 can also ensure that the first spring 65 is always in a deformed state, preventing the first spring 65 from falling off from the column 5 and the push plate 64.

[0052] In some of the above embodiments, the push plate 64 is arranged vertically, so the middle part of the push plate 64 is rotatably connected to the enclosure 612, a first spring 65 is arranged at the upper end to pull the upper end of the push plate 64, and the lower end is used to hit the waste. However, in addition to arranging the push plate 64 vertically, the push plate 64 can also be arranged horizontally, or even arranged at an angle, but these arrangements of the push plate 64 will take up a larger space for movement, and the other structural arrangements are also more complicated. However, the connection method can be summarized as follows: the middle part of the push plate 64 is rotatably connected to the enclosure 612, a first elastic member is arranged at the end of the push plate 64 away from the cutter to pull the push plate 64, and the push plate 64 is swung at the end close to the cutter to knock away the upper end of the swab tube 2 as waste.

[0053] The guide plate 622 has a discharge port 6221 on its underside, allowing the ejected waste to slide down from the underside. A stopper 6222 is located on the side of the discharge port 6221 away from the push plate 64. This blocker 6222 prevents the waste from moving forward, ensuring that it is discharged from the discharge port 6221. A waste bin is located below the discharge port 6221, secured between the first, second, and third slideways 31, 32, and 33, to receive the waste discharged from the discharge port 6221.

[0054] Combine Figure 9-10 As shown, the barcode scanning mechanism 7, located upstream of the tube cutting mechanism 6, is mounted on one side of the tube cutting mechanism 6. The barcode scanning mechanism 7 includes a driving wheel 74 mounted on the enclosure 612 and a driven wheel 721 mounted on the guide plate 622. The first and second slides 61 and 62 move toward each other, causing the driving wheel 74 and the driven wheel 721 to abut against the sides of the swab tube 2. The driving wheel 74 is driven by a barcode scanning motor 741, which rotates the swab tube 2 and cooperates with the camera to scan the barcode on the swab tube 2.

[0055] In order to adjust the clamping force of the code scanning mechanism 7 on the swab tube 2, the initial relative position of the driven wheel 721 with respect to the driving wheel 74 can be adjusted. Specifically, the guide plate 622 is fixedly connected to the mounting seat 71 on the side away from the first fixed plate 51. The mounting seat 71 is slidably connected to the adjustment plate 72 via a guide rail. The adjustment plate 72 is rotatably connected to the driven wheel 721 on the side of the mounting seat 71 close to the swab tube 2. The adjustment plate 72 is threadedly connected to a screw 722 on the side of the mounting seat 71 away from the swab tube 2, and the end of the screw 722 abuts against the mounting seat 71. The adjustment plate 72 is provided with a second elastic member on the side of the mounting seat 71 away from the swab tube 2. The two ends of the second spring 73 serving as the second elastic member are respectively hung on the mounting seat 71 and the adjustment plate 72. The second spring 73 ensures that the end of the screw 722 on the adjustment plate 72 always abuts against the mounting seat 71. As the screw rod 722 rotates, the second spring 73 elastically deforms, and the adjustment plate 72 slides relative to the mounting seat 71 to adjust the initial relative position of the driven wheel 721 relative to the driving wheel 74 .

[0056] Furthermore, two driven wheels 721 are provided and are arranged opposite to each other at the ends of the adjusting plate 72. The driving wheel 74 and the two driven wheels 721 are arranged in a triangle to ensure that the code scanning mechanism 7 can firmly clamp the swab tube 2.

[0057] The dilution mechanism, located downstream of the tube cutting mechanism 6, is mounted on the first fixed plate 51. The dilution mechanism includes a filling needle 8, which is mounted on the first fixed plate 51 via a bracket. The filling needle 8 injects diluent into the swab tube 2, which has moved downward, to dilute the sample on the swab 23. Other reagents, such as dyes, can also be added based on testing requirements.

[0058] Combine Figure 12-14 As shown, the tube extrusion mechanism 9 is located downstream of the dilution mechanism. Specifically, a second fixed plate 52 extending to the lower side of the workbench 3 is fixedly connected to the column 5. The second fixed plate 52 is slidably connected to the first slide 91 and the second slide 92 via a guide rail. The first slide 91 is provided with a first protruding tube extrusion head 911, and the second slide 92 is provided with a second protruding tube extrusion head 921. The first tube extrusion head 911 and the second tube extrusion head 921 are arranged opposite each other. As the two slides move toward each other, the two tube extrusion heads abut against the outer wall of the swab tube 2 to extrude and mix the swab tube 2. As the two slides move away from each other, the two tube extrusion heads separate, and the swab tube 2 continues to move along the second slide 32 and enters the subsequent workstation.

[0059] In order to drive the two slides to move, a rotatable second lead screw 93 is mounted on the second fixed plate 52. The two ends of the second lead screw 93 are respectively provided with screw parts with opposite rotation directions. The first slide 91 and the second slide 92 are respectively threadedly connected to the two screw parts, so that the second lead screw 93 is driven to rotate by the tube extrusion motor 931, so that the first slide 91 and the second slide 92 move away from each other or towards each other, thereby causing the two tube extrusion heads to move relative to each other.

[0060] To ensure the stability of the swab tube 2, the extrusion head should be positioned relatively low to align with the positioning of the guard plate 34 and the test tube rack 1. Therefore, the guard plate 34 has a clearance opening 341 through which the extrusion head passes, allowing it to abut against the swab tube 2. Furthermore, the first extrusion head 911 and the second extrusion head 921 respectively penetrate the through slots 14 on either side of the test tube rack 1 to ensure the stability of the swab tube 2.

[0061] Specifically, the slide has a sliding hole through which the extrusion ram passes, thereby enabling a sliding connection between the extrusion ram and the slide. A buffer is provided between the extrusion ram and the slide to cushion the impact of the contact between the extrusion ram and the swab tube 2. This buffer is a buffer spring 94, which is sleeved over the extrusion ram. A boss 95 is formed on the end of the extrusion ram near the swab tube 2, clamping the buffer spring 94 between the boss 95 and the slide.

[0062] To prevent the extrusion head from detaching from the slide, a nut 96 is fixed to the end of the slide away from the swab tube 2. Nut 96 acts as a stopper, abutting against the slide to limit the position of the extrusion head. A cushion 961 is provided between the stopper and the slide. The cushion 961 is sleeved over the extrusion head to cushion the impact of the extrusion head returning to its original position.

[0063] A soft pressing block 951 is embedded on the boss 95 of the tube squeezing head near one end of the swab tube 2. The soft pressing block 951 is formed with a concave surface 952 that contacts the swab tube 2. The concave surface 952 increases the tension of the soft pressing block 951 to ensure that the soft pressing block 951 fits the swab tube 2, thereby simulating the squeezing and mixing of the swab tube 2 by fingers.

[0064] In order to prevent the swab tube 2 from moving during the tube squeezing process, a positioning column 97 is provided on the first slide 91. The end of the positioning column 97 is close to the swab tube 2 relative to the end of the tube squeezing head; thus, as the first slide 91 slides, the positioning column 97 abuts against the swab tube 2 before the tube squeezing head, thereby positioning the swab tube 2.

[0065] Specifically, the first slide 91 has a mounting hole through which a positioning post 97 passes, thereby enabling a sliding connection between the positioning post 97 and the first slide 91. A spring element is provided between the extrusion head and the first slide 91 to cushion the impact of the contact between the positioning post 97 and the swab tube 2. This spring element is a compression spring 98, which is mounted over the positioning post 97. A protrusion is formed on one end of the positioning post 97 near the swab tube 2, clamping the compression spring 98 between the protrusion and the slide. Furthermore, to prevent the positioning post 97 from detaching from the first slide 91, the positioning post 97 is also equipped with a stopper and a cushion, which will not be described in detail here.

[0066] A conical pressing block 971 is formed on the protrusion of the positioning column 97 close to one end of the swab tube 2. The conical pressing block 971 presses the outer wall of the swab tube 2 to elastically deform the outer wall of the swab tube 2 to position the swab tube 2.

[0067] In this way, the tube squeezing mechanism 9 first squeezes the swab tube 2 through the movable positioning column 97 to position the swab tube 2; then the tube squeezing head moves relatively to squeeze the swab tube 2 to mix the sample and diluent inside the tube body 21.

[0068] In summary, the pre-treatment equipment of the present application completes the pre-treatment of the sample in the swab tube 2 by scanning the code, cutting the tube, diluting and squeezing the tube.

[0069] It will be understood that the present invention is described by way of some embodiments, and it will be appreciated by those skilled in the art that various changes or equivalent substitutions may be made to these features and embodiments without departing from the spirit and scope of the present invention. In addition, under the teachings of the present invention, these features and embodiments may be modified to adapt to specific circumstances and materials without departing from the spirit and scope of the present invention. Therefore, the present invention is not limited to the specific embodiments disclosed herein, and all embodiments falling within the scope of the claims of this application are intended to be protected by the present invention.

Claims

1. A pre-processing device, characterized in that: The swab tube comprises a tube cutting mechanism and a tube squeezing mechanism. The tube cutting mechanism comprises an upper cutter and a lower cutter that move relative to each other. The upper cutter and the lower cutter move toward each other to cut off the upper end of the swab tube, so that an incision is formed on the upper end of the swab tube for adding reagents. The tube squeezing mechanism squeezes the swab tube, causing the swab tube to deform elastically to mix the sample and reagent in the swab tube. A swingable push plate is provided on the upper side of the cutter, and the lower end of the push plate hits the upper end of the swab tube to knock away the waste material cut off from the upper end of the swab tube; The cutter cover is equipped with a material guide cover, and the waste material knocked away by the push plate slides along the inner cavity of the material guide cover; The material guide cover comprises a relatively movable enclosing plate and a guide plate, and an opening is formed on adjacent sides of the enclosing plate and the guide plate; As the cutter cuts the tube, the enclosure plate and guide plate are closed and the cover is arranged outside the swab tube; As the upper cutter and the lower cutter separate, the surrounding plate and the guide plate separate, so that the swab tube can move between the surrounding plate and the guide plate; The middle part of the push plate is rotatably connected to the enclosure plate. A first elastic member is provided at the end of the push plate away from the cutter to pull the push plate. The push plate swings at the end close to the cutter to knock away the waste. The enclosure is provided with a rotating shaft, and the push plate is provided with a straight hole arranged along the length direction, and the straight hole is for the rotating shaft to pass through; the enclosure is slidably connected to a guide shaft, and the end of the guide shaft is hinged to the lower end of the push plate, and the guide shaft limits the forward direction of the lower end of the push plate.

2. The pre-processing device according to claim 1, characterized in that: A rotatable driving wheel is provided on the enclosure, and a rotatable driven wheel is provided on the guide plate; the enclosure and the guide plate move toward each other, so that the driving wheel and the driven wheel respectively abut against the two sides of the swab tube, and the driving wheel drives the swab tube to rotate to cooperate with the camera to scan the code on the swab tube.

3. The pre-processing device according to claim 1, characterized in that: The tube squeezing mechanism includes a movable positioning column, and a first tube squeezing head and a second tube squeezing head that can move relatively. The positioning column squeezes the swab tube before the tube squeezing head to position the swab tube. The two tube squeezing heads move relative to each other, squeezing the outer wall of the swab tube to mix the sample and reagent inside the tube body.

4. The pre-processing device according to claim 3, characterized in that: The tube squeezing head is slidably connected to the slide seat; a buffer is provided between the tube squeezing head and the slide seat, and the buffer buffers the impact of the tube squeezing head and the swab tube in contact.

5. The pre-processing device according to claim 3, characterized in that: The swab tube is placed on a test tube rack; guard plates are formed on both sides of the test tube rack so that the test tube rack can move between the two guard plates; the tube squeezing head penetrates the guard plates and the test tube rack and abuts against the outer wall of the swab tube.

Citation Information

Patent Citations

  • Swab sample separation device

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