An automatic early warning method for the lifespan of a kit and a urine analyzer system

Abstract

The present invention discloses a method for automatically warning the lifespan of a kit and a urine analyzer system. The method for automatically warning the lifespan of the kit includes: sending the collected temperature data of the kit to the server according to a preset period; the server determines the target reagent that needs to be self-checked in the kit based on the temperature data of the kit; based on the received self-check command for the target reagent sent by the server, detecting the target reagent and sending the detection result to the server; the server determines whether each of the target reagents is a failed reagent according to the detection results of each of the target reagents; and when there is a failed reagent, shielding the sample detection item corresponding to the failed reagent and sending out a warning message for the lifespan of the kit. By adopting the method for automatically warning the lifespan of the kit of the present invention, on the one hand, reagents are not wasted, and on the other hand, the accuracy of the detection result can be ensured.

Description

Technical Field

[0001] The present invention relates to the field of detection technology, and particularly to a method for automatically warning the life of a kit and a urine analyzer system. Background Art

[0002] With the increase of human lifespan, the importance of healthcare and maintenance has received more and more attention. Currently, there are already household detection devices for users to perform personal physical item detections at home, such as detections of items like urine and saliva.

[0003] The existing methods for managing the life of kits are generally based on the number of uses, the date after opening, or the expiration date. If the reagent exceeds the limit of the reagent storage temperature requirement for too long, it may cause changes in the properties of the reagent, and then lead to the deviation or invalidation of the test data of the current sample. That is, the existing methods for managing the life of kits have low reliability and are prone to inaccurate detection results. Summary of the Invention

[0004] The purpose of the present invention is to provide a method for automatically warning the life of a kit and a urine analyzer system to solve the above problems. For this purpose, the technical solutions adopted by the present invention are as follows:

[0005] According to an embodiment of the present invention, a method for automatically warning the life of a kit is provided, and the method includes:

[0006] Sending the temperature data of the collected kit to the server at a preset period;

[0007] The server determines the target reagent that needs to be self-checked in the kit based on the temperature data of the kit;

[0008] Based on the self-check command for the target reagent sent by the server received, detecting the target reagent and sending the detection result to the server;

[0009] The server determines whether each target reagent is a failed reagent according to the detection results of each target reagent; and when there is a failed reagent, shielding the sample detection item corresponding to the failed reagent and sending out a warning message for the life of the kit.

[0010] In a preferred embodiment, the self-check includes:

[0011] Pumping the target reagent into the reaction chamber; and

[0012] Measuring the light transmittance intensity of the target reagent in the reaction chamber.

[0013] In a preferred embodiment, the server determines whether each target reagent is a failed reagent, including:

[0014] Compare the received light intensity value of the target reagent with the preset light intensity value of the target reagent. If the difference is within the preset range, it is determined that the target reagent is not a failed reagent.

[0015] In a preferred embodiment, the preset light intensity value is the light intensity data detected for the first time after the kit is replaced.

[0016] In a preferred embodiment, the preset range is ±5% of the preset light intensity value.

[0017] In a preferred embodiment, the temperature data of the kit is sent in the form of a heartbeat packet, and the preset period is 10 minutes.

[0018] In a preferred embodiment, determining the target reagent that needs to be self-checked in the kit based on the temperature data of the kit includes:

[0019] Create a temperature change curve showing how the temperature data of the kit changes over time;

[0020] Overlay the temperature change curve with the limit values of the reagent storage temperature requirements for each reagent in the dimension with time as the abscissa;

[0021] Calculate the cumulative time for each reagent to exceed the limit value of the reagent storage temperature requirements; and

[0022] When the cumulative time exceeds the preset threshold, determine the corresponding reagent as the target reagent that needs to be self-checked in the kit.

[0023] In a preferred embodiment, determining the target reagent that needs to be self-checked in the kit based on the temperature data of the kit further includes:

[0024] When the first threshold value of exceeding the limit value of the reagent storage temperature requirements is reached for the first preset duration, determine the corresponding reagent as the target reagent that needs to be self-checked; and when the second threshold value of exceeding the limit value of the reagent storage temperature requirements is reached for the second preset duration, determine the reagent as the failed reagent;

[0025] Wherein, the second threshold value is greater than the first threshold value, and the second preset duration is greater than the first preset duration.

[0026] In a preferred embodiment, the method further includes: after the server determines that the target reagent is not a failed reagent, reset the cumulative time of the target reagent to 0.

[0027] In a preferred embodiment, the kit life warning information includes one or more of text, icons, and sounds.

[0028] According to another aspect of the present invention, there is provided a urine analyzer system, wherein the urine analyzer system includes a urine analyzer and a server. The urine analyzer is installed in a toilet and is used to detect urine. The urine analyzer and the server are wirelessly communicatively connected to execute the automatic warning method for the kit life as described above.

[0029] The present invention improves the problem that when multiple reagents with different storage requirements are stored in the same kit, the storage status of each reagent cannot be tracked individually (the temperature calibration range of each reagent can be set separately in the background). Individually shielding the expired reagents can extend the service life of the entire kit and avoid the blockage or contamination of the flow channel by the expired and deteriorated reagents. Since the changes in the properties of the reagents do not all occur instantaneously and there may be an accumulation process during this period, continuous monitoring of the temperature fluctuations is required to better evaluate the storage status of the reagents and reduce the waste of reagents caused by frequent periodic detections. Therefore, by adopting the method of the present invention, on the one hand, reagents are not wasted, and on the other hand, the accuracy of the detection results can be ensured. BRIEF DESCRIPTION OF THE DRAWINGS

[0030] Figure 1 is a specific flowchart of the automatic warning method for the kit life of the present invention;

[0031] Figure 2 is a flowchart for determining the target reagent that needs to be self-checked based on the kit temperature data in the method of the present invention;

[0032] Figure 3 is a schematic diagram of the curve based on the kit temperature data in the method of the present invention. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0033] The following will describe the preferred embodiments of the present invention in detail with reference to the accompanying drawings so as to more clearly understand the purpose, features and advantages of the present invention. It should be understood that the embodiments shown in the drawings are not limitations on the scope of the present invention, but only to illustrate the essential spirit of the technical solution of the present invention.

[0034] In the following description, certain specific details are set forth for purposes of explaining various disclosed embodiments to provide a thorough understanding of the various disclosed embodiments. However, one of ordinary skill in the relevant art will recognize that the embodiments may be practiced without one or more of these specific details. In other instances, well-known devices, structures, and techniques associated with the present application may not be shown or described in detail so as not to unnecessarily obscure the description of the embodiments.

[0035] References to "one embodiment" or "an embodiment" in the course of the specification mean that a particular feature, structure, or characteristic described in connection with the embodiment is included in at least one embodiment. Thus, appearances of the phrases "in one embodiment" or "in an embodiment" in various places throughout the specification are not necessarily all referring to the same embodiment. Additionally, the particular features, structures, or characteristics may be combined in any manner in one or more embodiments.

[0036] In the following description, in order to clearly show the structure and working mode of the present invention, many directional terms will be used for description. However, terms such as "front", "rear", "left", "right", "outer", "inner", "outward", "inward", "up", "down", etc. should be understood as convenient terms and should not be construed as limiting terms.

[0037] As Figure 1 shown, the first embodiment of the present invention relates to a method for automatically warning the lifespan of a kit, and the method includes:

[0038] S1. Send the temperature data of the collected kit to the server according to a preset period.

[0039] Specifically, the detection device (for example, an urine analyzer) is built-in with a temperature sensor, which can be used to measure the ambient temperature (i.e., the kit temperature). The kit temperature data of the device is sent to the server in a periodic (such as every 10 minutes) heartbeat packet manner.

[0040] S2. The server determines the target reagent that needs to be self-checked in the kit based on the temperature data of the kit. As Figure 2 shown, the specific process is as follows:

[0041] 101. Make a temperature change curve of the kit temperature data over time. For example, draw a point every 10 minutes, and then connect the points with a straight line to form a curve;

[0042] 102. Superimpose the temperature change curve and the reagent storage temperature requirement limit value Ts (usually room temperature, 25 °C) in the dimension with time as the abscissa, as Figure 3 shown;

[0043] 103. Calculate the cumulative time t for each reagent exceeding the reagent storage temperature requirement limit value respectively, Figure 3 where t = (t2 - t1) + (t4 - t3) + (t6 - t5);

[0044] 104. When the cumulative time t exceeds the preset threshold, determine the corresponding reagent as the target reagent that needs to be self-checked in the kit.

[0045] For different reagents, the limit value Ts of the reagent storage temperature requirement is not the same. Additionally, the greater the degree and the longer the time exceeding the limit value of the reagent storage temperature requirement, the greater the likelihood of reagent failure. When the first threshold of exceeding the limit value of the reagent storage temperature requirement reaches the first predetermined duration, the corresponding reagent is determined as the target reagent that needs to be self-checked; and when the second threshold of exceeding the limit value of the reagent storage temperature requirement reaches the second predetermined duration, the reagent is determined as a failed reagent, where the second threshold is greater than the first threshold, and the second predetermined duration is greater than the first predetermined duration. In a specific embodiment, if the cumulative exceedance of room temperature by 5°C (i.e., the first threshold of Ts is 30°C) reaches 24 hours, the corresponding reagent is determined as the target reagent that needs to be self-checked, a reagent life calibration self-check instruction is issued, and a temporary test configuration document is actively pushed to the device end; if the cumulative exceedance of room temperature by 10°C (i.e., the second threshold of Ts is 35°C) reaches 72 hours, a kit life warning message is issued to remind the user to replace the kit in a timely manner.

[0046] S3. Based on the self-check command for the target reagent sent by the received server, detect the target reagent and send the detection result to the server.

[0047] Specifically, when the device is in an idle period without user sample detection, the single reagent life calibration self-check process is preferentially executed. The reagent life calibration self-check process is carried out by the optical detection device of the device (such as a urine analyzer). Specifically, the reagent is pumped into the reaction chamber of the device; and the light transmittance intensity of the target reagent in the reaction chamber is measured. The optical detection device has advantages such as small volume and convenient detection. Specifically, the optical detection device includes a light source and an optical sensor, and the light source and the optical sensor are respectively placed on both sides of the reaction chamber, so that the light emitted by the light source passes through the liquid in the reaction chamber and is received by the optical sensor. The light source can be an LED lamp. The LED lamp can emit lights of different wavelengths as needed. That is, for different reagents, the wavelengths of the detection lights can be the same or different. The optical sensor is used to measure the light transmittance intensity of the target reagent in the reaction chamber.

[0048] S4. The server determines whether each target reagent is a failed reagent according to the detection results of each target reagent; and when there is a failed reagent, the sample detection item corresponding to the failed reagent is blocked and a kit life warning message is issued.

[0049] When the detection result has a high consistency with the preset data (for example, the difference is within ±5%), the reagent is considered to still be available. If it is self-checked and found that the detection result deviates from the preset data beyond the preset range (that is, ±5% of the preset light intensity value), the reagent is considered unavailable, that is, the target reagent is a failed reagent; push the temporary test configuration document to the device side, and skip the test items that need to use this reagent in the sample test before replacing the reagent kit in the future, that is, block the test items corresponding to the failed reagent, and only execute the test items for which the reagent is still in an available state, and issue a reagent kit life warning message to prompt the user to replace the reagent kit. At the same time, after the server determines that the target reagent is not a failed reagent, reset the cumulative time of the target reagent to 0, that is, recalculate the cumulative time that the reagent exceeds the limit value of the reagent storage temperature requirement.

[0050] Preferably, the preset data (that is, the preset light intensity value) is the data obtained from the first self-check after replacing the reagent kit to avoid system differences between devices. Of course, the preset data can also be obtained through experiments in advance and saved on the server and the device side.

[0051] Each test item may include one or more indicators. The indicators include but are not limited to: urinary pH, urinary white blood cells (WBC / LEU), urinary nitrite (NIT), urinary protein (PRO), glucose (GLU), urobilinogen (URO / UBG), ketone bodies (KET), occult blood (BLU), bilirubin (BIL), ascorbic acid (VC), salts, creatinine (CrE), and may also include indicators of tumor markers, such as alpha-fetoprotein, carcinoembryonic antigen, albumin, urinary beta2-microglobulin, etc., and microbial detection indicators, such as nicotine, ethanol, vitamin C, etc. For example, for the urine routine test item, it includes urinary white blood cells, urinary pH, urinary ketone bodies, urinary nitrite, urobilinogen, urinary bilirubin, urinary protein, glucose, occult blood, and vitamin C. To detect these indicators, different reagents need to be added. Therefore, the configuration file contains various reagents and dosages required for the corresponding indicators of each test item. When the reagent fails, it is necessary to change the configuration file in the background, set this test item as undetectable, and issue it to avoid inaccurate measurement results caused by reagent failure.

[0052] Preferably, the reagent kit life warning message is displayed on the APP of the user's mobile phone. For example, it reminds the user to replace the reagent kit in a timely manner by one or more of the ways such as text, icon, and sound. The text and icon can be displayed in the way of yellow + flashing, for example.

[0053] The automatic warning method for the kit life of the present invention improves the problem that when multiple reagents with different storage requirements are stored in the same kit, the storage status of each reagent cannot be tracked separately (the temperature calibration interval of each reagent can be set separately in the background). Individually shielding the expired reagents can extend the service life of the entire kit and avoid the blockage or contamination of the flow channel by the expired and deteriorated reagents. Since the changes in the properties of the reagents do not all occur instantaneously and there may be an accumulation process during this period, continuous monitoring of the temperature fluctuations is required to better evaluate the storage status of the reagents and reduce the waste of reagents caused by frequent periodic detections.

[0054] The second embodiment of the present invention also discloses a urine analyzer system, which includes a urine analyzer and a server. The urine analyzer is installed in the toilet and is used to detect urine. The urine analyzer and the server are wirelessly communicatively connected to execute the automatic warning method for the kit life as described above. On the one hand, it does not waste reagents, and on the other hand, it can ensure the accuracy of the detection results. The structure of this urine analyzer has been described in detail in the patent applications of the present applicant with the publication numbers CN113945709A and CN113820480A, and will not be elaborated here.

[0055] The server includes at least one processor and a memory communicatively connected to the at least one processor; wherein, the memory stores a computer program, and when the computer program is executed by the at least one processor, it can perform information interaction with the urine analyzer, so as to implement the above-mentioned automatic warning method for the kit life.

[0056] Exemplarily, the computer program can be divided into one or more modules / units. The one or more modules / units are stored in the memory and executed by the processor to complete the present invention. The one or more modules / units can be a series of computer program instruction segments capable of performing specific functions, and these instruction segments are used to describe the execution process of the computer program in the terminal device.

[0057] The terminal device can be a computing device such as a desktop computer, a notebook, a palm computer, and a cloud server. The terminal device may include, but is not limited to, a processor and a memory. For example, it may further include input / output devices, network access devices, a bus, etc.

[0058] The processor can be a Central Processing Unit (CPU), or can also be other general-purpose processors, Digital Signal Processors (DSPs), Application Specific Integrated Circuits (ASICs), Field-Programmable Gate Arrays (FPGAs), or other programmable logic devices, discrete gate or transistor logic devices, discrete hardware components, etc. The general-purpose processor can be a microprocessor or the processor can also be any conventional processor, etc. The processor is the control center of the terminal device, and connects all parts of the entire terminal device using various interfaces and lines.

[0059] The memory can be used to store the computer programs and / or modules. The processor realizes various functions of the terminal device by running or executing the computer programs and / or modules stored in the memory, and by invoking the data stored in the memory. The memory mainly includes a program storage area and a data storage area. Among them, the program storage area can store an operating system, application programs required for at least one function (such as a sound playback function, an image playback function, etc.); the data storage area can store data created according to the use of the mobile phone (such as audio data, phone book, etc.). In addition, the memory can include high-speed random access memory, and can also include non-volatile memory, such as a hard disk, memory, plug-in hard disk, Smart Media Card (SMC), Secure Digital (SD) card, Flash Card, at least one magnetic disk storage device, flash memory device, or other volatile solid-state storage devices.

[0060] When each module / unit of a computer program is implemented in the form of a software functional unit and sold or used as an independent product, it can be stored in a computer-readable storage medium. Based on this understanding, to implement all or part of the processes in the above-described embodiment methods of the present invention, it can also be completed by instructing relevant hardware through a computer program. The computer program can be stored in a computer-readable storage medium. When the computer program is executed by a processor, the steps of the above-described various method embodiments can be implemented. Among them, the computer program includes computer program code, and the computer program code can be in the form of source code, object code, executable file, or some intermediate form, etc. The computer-readable medium can include: any entity or device capable of carrying the computer program code, recording medium, USB flash drive, mobile hard disk, magnetic disk, optical disc, computer memory, read-only memory (ROM, Read-Only Memory), random access memory (RAM, Random Access Memory), electrical carrier signal, telecommunication signal, and software distribution medium, etc. It should be noted that the content included in the computer-readable medium can be appropriately increased or decreased according to the requirements of legislation and patent practice in the jurisdiction. For example, in some jurisdictions, according to legislation and patent practice, the computer-readable medium does not include electrical carrier signals and telecommunication signals.

[0061] The preferred embodiments of the present invention have been described in detail above. However, it should be understood that if necessary, aspects of the embodiments can be modified to adopt aspects, features, and concepts of various patents, applications, and publications to provide additional embodiments.

[0062] In view of the detailed description above, these and other changes can be made to the embodiments. Generally speaking, in the claims, the terms used should not be considered as limited to the specific embodiments disclosed in the specification and claims, but should be understood to include all possible embodiments together with the entire equivalent scope enjoyed by these claims.

Claims

1. An automatic warning method for the lifespan of a kit, characterized in that, The method includes: Sending the temperature data of the reagent kit collected at a preset period to the server; The server determines the target reagent in the reagent kit that needs to be self - tested based on the temperature data of the reagent kit. Specifically, it includes: Making a temperature change curve of the temperature data of the reagent kit changing with time; Superimposing the temperature change curve and the limit values of the reagent storage temperature requirements of each reagent in the dimension with time as the abscissa; Calculating the cumulative time that each reagent exceeds the limit value of the reagent storage temperature requirement respectively; and When the cumulative time exceeds a preset threshold, determining the corresponding reagent as the target reagent that needs to be self - tested in the reagent kit; Based on the self - test command for the target reagent sent by the server received, detecting the target reagent and sending the detection result to the server; The server determines whether each target reagent is a failed reagent according to the detection results of each target reagent; and when there is a failed reagent, shielding the sample detection item corresponding to the failed reagent and sending out a reagent kit life warning message.

2. The method for automatically warning the lifespan of the kit according to claim 1, wherein, The self - test includes: Pumping the target reagent into the reaction chamber; and Measuring the light transmittance intensity of the target reagent in the reaction chamber.

3. The method for automatically warning the service life of the kit according to claim 2, wherein The server determines whether each target reagent is a failed reagent, including: Comparing the received light intensity value of the target reagent with the preset light intensity value of the target reagent. If the difference is within a preset range, it is determined that the target reagent is not a failed reagent.

4. The method for automatically warning of the kit life according to claim 3, characterized in that, The preset light intensity value is the data detected for the first time after the reagent kit is replaced.

5. The method for automatically warning the lifespan of the kit according to claim 3, wherein, The preset range is ±5% of the preset light intensity value.

6. The method for automatically warning of the kit life according to claim 1, characterized in that, The temperature data of the reagent kit is sent by means of a heartbeat packet, and the preset period is 10 minutes.

7. The method for automatically warning the lifespan of the kit according to claim 1, wherein It also includes: When the first threshold value of exceeding the limit value of the reagent storage temperature requirement is reached for the first preset duration, determining the corresponding reagent as the target reagent that needs to be self - tested; And When the second threshold value of exceeding the limit value of the reagent storage temperature requirement is reached for the second preset duration, determining the reagent as the failed reagent; Wherein, the second threshold value is greater than the first threshold value, and the second preset duration is greater than the first preset duration.

8. The method for automatically warning the life of the kit according to claim 1, wherein It also includes: After the server determines that the target reagent is not a failed reagent, resetting the cumulative time of the target reagent to 0.

9. The method for automatically warning the lifespan of the kit according to claim 1, wherein The reagent kit life warning message includes one or more of text, icon and sound.

10. A urine analyzer system, characterized in that, The urine analyzer system includes a urine analyzer and a server. The urine analyzer is installed in the toilet and is used to detect urine. The urine analyzer and the server are wirelessly communicatively connected to execute the reagent kit life automatic warning method as described in any one of claims 1 - 9.

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