A dynamic rat intervertebral disc distraction system

Abstract

The application discloses a dynamic traction system for rat intervertebral disc, which comprises a base, a plurality of first clamps arranged on the base, a plurality of first sliding rails arranged on the base, a sliding block arranged on each first sliding rail, a second clamp arranged on the sliding block, a second sliding rail arranged on the base, a movable plate movably arranged on the second sliding rail, a plurality of springs arranged on the movable plate and corresponding to the first sliding rails, one end of each spring being connected with the movable plate and the other end of each spring being connected with a sliding block, and a driving device for driving the movable plate to move back and forth. The application has the beneficial effect that periodic traction experiments on a plurality of rat tails can be simultaneously conducted by the driving device to simulate lumbar traction used in clinical treatment. The pulling force is transmitted by the springs, and the size of the pulling force can be conveniently and quickly adjusted by adjusting the number of the springs, the elastic coefficient and the stretching length of the springs, so that physical damage to the rat tails is avoided.

Description

Technical Field

[0001] The present invention relates to the technical field of orthopedics, and in particular to a dynamic traction system for rat intervertebral discs. Background Art

[0002] Diseases caused by intervertebral disc degeneration are called degenerative disc diseases, and include a range of common clinical spinal diseases, such as lumbar disc herniation and degenerative scoliosis. To further explore the influencing factors and pathogenesis of intervertebral disc degeneration, traction is often performed on the animal spine, particularly the rat's tail, to simulate clinical lumbar traction. This allows for observation of traction effects through magnetic resonance imaging data and histological analysis of nucleus pulposus water content, providing essential information and theoretical basis for clinical treatment plans. Summary of the Invention

[0003] The purpose of the present invention is to provide a rat intervertebral disc dynamic traction system for applying mechanical stimulation experiments to rat intervertebral discs.

[0004] To achieve the above object, the present invention provides the following technical solutions:

[0005] A dynamic traction system for rat intervertebral discs, comprising a base, on which are provided a plurality of holders for fixing rats and a plurality of first clamps for fixing the rat's coccyx; a plurality of first slide rails are provided on the base corresponding to the first clamps, and the first slide rails are arranged parallel to each other along the stretching direction; a slider is movably provided on each of the first slide rails, and a second clamp is provided on each of the sliders for fixing the next section of the rat's coccyx; a second slide rail is also provided on the base along the stretching direction, and a movable plate is movably provided on the second slide rail, and a plurality of springs are replaceably provided on the movable plate corresponding to the first slide rail; each of the springs is connected to the movable plate at one end and to the slider at the other end; and the system also comprises a driving device for driving the movable plate to reciprocate along the stretching direction, so as to drive the slider to move along the first slide rail by transmitting tension and thrust through the spring, thereby applying dynamic traction to the rat's coccyx.

[0006] Preferably, the first clamp and the second clamp both comprise a through hole for the rat's tail to pass through, and a fixing hole transversely connected to the through hole, wherein a Kirschner wire for fixing the rat's coccyx is arranged in the fixing hole.

[0007] Preferably, a first sleeve for the rat's tail to pass through is provided in the through hole, and the Kirschner wire pierces the first sleeve to fix the rat's tail vertebrae.

[0008] Preferably, a second sleeve is sleeved on the Kirschner wire, the first sleeve and the second sleeve are both made of silicone or soft plastic, and the Kirschner wire is arranged in the second sleeve through interference fit.

[0009] Preferably, the Kirschner wire on the first clamp is used to fix the seventh coccyx of the rat, and the Kirschner wire on the second clamp is used to fix the eighth coccyx of the rat.

[0010] Preferably, the driving device is a linear motor, a cylinder or a motor-driven cam structure.

[0011] Preferably, the frequency range of the reciprocating movement of the movable plate along the stretching direction is 0-5 Hz.

[0012] The beneficial effects of the present invention are:

[0013] The driving device can be used to periodically and simultaneously perform traction comparison experiments on multiple rat tails. The applied pulling force is transmitted through springs, and the magnitude of the pulling force can be conveniently adjusted by adjusting the number of springs, their elastic coefficients, and the stretching length, thereby avoiding physical damage to the rat tails. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] Figure 1 It is a schematic diagram of the three-dimensional structure of the present invention;

[0015] Figure 2 It is a structural diagram of part of the structure of the present invention. DETAILED DESCRIPTION

[0016] The technical solution of this patent is further described in detail below in conjunction with specific implementation methods.

[0017] In the description of the present invention, it should be noted that the terms "inside", "outside", "up", "down", "horizontal", etc., indicating orientations or positional relationships, are based on the orientations or positional relationships shown in the accompanying drawings. They are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation. Therefore, they cannot be understood as limiting the present invention.

[0018] like Figure 1 and Figure 2As shown, a multi-channel rat coccyx vibrator according to the present invention includes a base 10, on which are disposed multiple first clamps 12, and multiple first slide rails 14 corresponding to the first clamps 12. Each first slide rail 14 is provided with a slider 26, and a second clamp 18 is provided on the slider 26 to secure the rat's tail. The multiple first clamps 12 and second clamps 18 facilitate simultaneous experiments on multiple rats and facilitate comparison. With the axial direction of the rat's tail as the stretching direction, a second slide rail 22 is provided on the base 10 along the stretching direction. A movable plate 16 is movably disposed on the second slide rail 22, and multiple springs 28 are provided on the movable plate 16 corresponding to the second clamps 18. One end of the spring 28 is connected to the slider 26, and the other end is connected to the movable plate 16. A drive device (not shown) is also included to drive the movable plate 16 back and forth along the stretching direction. The drive device can be a linear motor, a pneumatic cylinder, or a servo motor and its driven screw, or a motor-driven cam structure. Because these various implementations are well known in the industry, they are not shown in the figure.

[0019] The invention relates to a novel mechanical device for the treatment of rats. The invention relates to a mechanical device for the treatment of rats. The mechanical device comprises a driving device, a movable plate 16, and a movable plate 16. The driving device periodically drives the movable plate 16 to move back and forth along the stretching direction. The movable plate 16 is subjected to pulling and pushing forces by a spring 28, thereby applying periodic tensile stress to the rat's coccyx between the first fixture 12 and the second fixture 18, thereby conveniently observing its effect on the rat's coccyx intervertebral disc. The movement of the driving device is converted into the movement of the movable plate 16 by the elastic force of the spring 28. The movement of the movable plate 16 is first buffered by the spring 28 to avoid excessive momentary force causing physical damage to the rat's tail. Secondly, the spring 28 converts the pulling force of the driving device into a smaller elastic force. The above structure can be realized by a common motor, and multiple rat coccyx intervertebral discs can be mechanically stimulated simultaneously. During the mechanical stimulation, the pulling force of the rat's tail can also be measured according to the stretched length of the spring 28, avoiding the shortcoming that the pulling force cannot be effectively measured when adopting other methods.

[0020] The spring 28 is replaceable, so the length and elastic coefficient of the spring 28 can be adjusted to adjust the tension applied to the rat's tail.

[0021] Furthermore, the frequency of the reciprocating movement of the movable plate 16 along the stretching direction is 0-5 Hz.

[0022] Furthermore, the first clamp 12 and the second clamp 18 both include through holes (not shown) for Kirschner wires to pass through, and the Kirschner wires (not shown) are used to fix the rat tail.

[0023] Both the first clamp 12 and the second clamp 18 include a through hole for the rat's tail to pass through, and a fixing hole that connects laterally to the through hole. A Kirschner wire for securing the rat's coccyx is positioned within the fixing hole. A first sleeve 30 for the rat's tail to pass through is positioned within the through hole. The Kirschner wire pierces the first sleeve 30 to secure the rat's coccyx. A second sleeve 32 is sleeved over the Kirschner wire. Both the first sleeve 30 and the second sleeve 32 are made of silicone or soft plastic. The Kirschner wire is positioned within the second sleeve 32 via an interference fit. The beneficial effect of the above method is that the Kirschner wire passes through the first sleeve 30 to secure the rat's coccyx, and the Kirschner wire is sleeved with the second sleeve 32. This allows the Kirschner wire to form a stable structure within the first clamp 12 or the second clamp 18, preventing significant movement relative to the first clamp 12 or the second clamp 18. This reduces vibration of the Kirschner wire itself during the reciprocating movement of the second clamp 18, thereby significantly reducing pain caused to the rat.

[0024] Furthermore, the Kirschner wire on the first clamp 12 is used to fix the seventh coccyx of the rat, and the Kirschner wire on the second clamp 18 is used to fix the eighth coccyx of the rat. Experiments show that performing the above experiment on the seventh and eighth coccyx vertebrae causes less pain to the rats and has a significant effect.

[0025] The above descriptions are merely embodiments of the present invention and are not intended to limit the patent scope of the present invention. Any equivalent structure or equivalent process transformation made using the contents of the present invention's description and drawings, or directly or indirectly applied in other related technical fields, are also included in the patent protection scope of the present invention.

Claims

1. A dynamic traction system for rat intervertebral discs, comprising a base, characterized in that: The base is provided with a plurality of holders for fixing rats and a plurality of first clamps for fixing the rat's coccyx; the base is provided with a plurality of first slide rails corresponding to the first clamps, and the first slide rails are arranged parallel to each other along the stretching direction; a slider is movably provided on each of the first slide rails, and a second clamp for fixing the next section of the rat's coccyx is provided on the slider; the base is also provided with a second slide rail along the stretching direction, and a movable plate is movably provided on the second slide rail, and a plurality of springs are replaceably provided on the movable plate corresponding to the first slide rail; each of the springs is connected to the movable plate at one end and to the slider at the other end; and a driving device for driving the movable plate to reciprocate along the stretching direction is also included, so as to drive the slider to move along the first slide rail by transmitting tension and thrust through the spring, thereby applying dynamic traction to the rat's coccyx; The first clamp and the second clamp each comprise a through hole for the rat's tail to pass through, and a fixing hole laterally connected to the through hole, wherein a Kirschner wire for fixing the rat's coccyx is arranged in the fixing hole; The frequency range of the reciprocating movement of the movable plate along the stretching direction is 0-5HZ.

2. The rat intervertebral disc dynamic traction system according to claim 1, characterized in that: A first sleeve for the rat's tail to pass through is arranged in the through hole, and the Kirschner wire pierces the first sleeve to fix the rat's tail vertebrae.

3. The rat intervertebral disc dynamic traction system according to claim 2, characterized in that: A second sleeve is sleeved on the Kirschner wire. The first sleeve and the second sleeve are both made of silicone or soft plastic. The Kirschner wire is arranged in the second sleeve through interference fit.

4. The rat intervertebral disc dynamic traction system according to claim 3, characterized in that: The Kirschner wire on the first fixture is used to fix the seventh coccyx of the rat, and the Kirschner wire on the second fixture is used to fix the eighth coccyx of the rat.

5. The rat intervertebral disc dynamic traction system according to claim 1, characterized in that: The driving device is a linear motor, a cylinder or a cam structure driven by a motor.

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