Portable Breath Gas and Volatile Substance Analyzer

By designing a portable breath gas and volatile substance analyzer, using the combination of breath input, transport, storage and sensors, the problem of difficulty in analyzing low-concentration gases and high relative humidity gases in the prior art is solved, and efficient and accurate disease monitoring is achieved.

CN115038380BActive Publication Date: 2025-06-10ヘルスイノヴィジョンカンパニーリミテッド
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Patent Information

Application Number
CN202080080129.1
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Priority Date
2019-11-14
Filing Date
2020-11-13
Publication Date
2025-06-10
Estimated Expiration
2040-11-13

AI Technical Summary

Technical Problem

The prior art is difficult to effectively analyze the atmosphere of low concentration gases and high relative humidity, and cannot meet the needs for disease monitoring.

Method used

A portable breath gas and volatile substance analyzer is designed, using a combination of breath input part, breath transport part, breath storage part, sensor and microcontroller. By controlling the breath flow mode and using appropriate sensors, it can analyze the breath of low concentration gas and high relative humidity.

Benefits of technology

It realizes efficient analysis of low-concentration gases and high relative humidity atmospheres, providing accurate results comparable to traditional blood draw or urine tests, and conveniently and quickly monitors disease conditions.

✦ Generated by Eureka AI based on patent content.

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Abstract

The present invention relates to a portable breath gas and volatile substance analyzer, which includes a breath input part for inputting breath into the analyzer by blowing, a breath delivery part connected to the breath input part, a breath storage part connected to the breath delivery part, a sensor provided in the breath storage part for detecting breath, and a microcontroller connected to the sensor, and the microcontroller is used to receive breath data from the sensor to analyze data of gases and volatile substances.
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Description

Technical Field

[0001] Engineering related to portable breath gas and volatile substance analyzers. Background Art

[0002] Breathing is a continuous physical activity of organisms. Under normal conditions, inhalation and exhalation occur as naturally as the heartbeat. Obviously, breathing is a crucial process that creates balance in different processes within the organism. Therefore, the breath from an organism's breathing is an important signal that can indicate early signs of internal imbalance or abnormality. In addition, biomedical research has long recognized that diseases caused by internal abnormalities in the human body can lead to gas molecules or volatile organic compounds (VOCs) in the respiratory system, which are released along with the breath. Gas molecules or volatile organic compounds are related to the functional state of cells, tissues, microbiomes, or microorganisms in the body, which is an important indication of human health in terms of disease development.

[0003] Therefore, attempts have been made to design methods and devices for analyzing or monitoring disease conditions by analyzing the gases and / or volatile substances present in the breath. For example, by measuring the concentration of acetone gas present in the breath, which is significantly correlated with the blood sugar level of diabetic patients. This correlation can indicate diabetes and blood sugar levels without the need for an additional blood-drawing step.

[0004] Research and documents related to devices or methods for analyzing breath gases or volatile substances indicating disease identity have been made public. Examples of the prior art are as follows.

[0005] U.S. Patent No. 2013 / 0259748 A1 discloses a breath acetone gas sensing device, which includes: a chamber for accommodating a breath gas sample; an acetone gas sensor placed in the chamber, which is used to generate an output current in response to the acetone concentration of the acetone gas in the breath sample; a heating device for heating the acetone gas sensor; and a measurement unit coupled to the acetone gas sensor for providing a measurement signal corresponding to the output current.

[0006] U.S. Patent No. 2008 / 0077037 A1 discloses a medical diagnostic device for analyzing breath gases and / or skin emissions, which includes a highly sensitive sensing component for obtaining an emission concentration profile and a database of medical condition characteristics of breath analysis profiles.

[0007] U.S. Patent No. 6,341,520 B1 discloses a method and apparatus for analyzing a breath sample, capable of analyzing the amount of gas contained in the breath through the cooperation of a chromatographic column, a data processor, a breath sample receiving tube, a gas storage tank, and a gas valve. The components work automatically and cooperatively during the operation cycle.

[0008] Although the devices for analyzing breath gas according to the above prior art can analyze gases, there are still limitations because they are not designed specifically for breaths with low-concentration gases and high relative humidity. SUMMARY OF THE INVENTION

[0009] An object of the present invention is to invent a breath gas and volatile substance analyzer that is easy to use, portable, and has high analysis efficiency for gases and volatile substances. The dynamics of the gas to be analyzed are considered during the invention process of the analyzer, enabling the analysis of breath gas and volatile substances even when their concentrations are extremely low (e.g., concentrations below 5 ppm). The relative humidity in the breath is also considered during its invention process.

[0010] The portable breath gas and volatile substance analyzer according to the present invention includes a breath input portion for inputting breath into the analyzer by blowing, a breath delivery portion connected to the breath input portion, a breath storage portion connected to the breath delivery portion, a sensor provided in the breath storage portion for detecting the breath, and a microcontroller connected to the sensor for receiving breath data from the sensor to analyze data on gases and volatile substances. The breath input portion includes a mouthpiece having a breath input channel for the user to blow, a breath flow adjustment tube connected to the mouthpiece, and an end portion connected to the breath flow adjustment tube having a breath output channel. The breath flow adjustment tube includes a main tube disposed between the mouthpiece and the end portion of the breath input portion, and a breath delivery tube disposed below the main tube, which serves as a channel allowing the breath to continue flowing to the breath delivery portion. Preferably, the breath delivery tube is provided at a position 0.5 mm to 75 mm horizontally from the mouthpiece.

[0011] The portable breath gas and volatile substance analyzer according to the present invention can analyze breath gas and volatile substances indicating disease characteristics, which provides technical advantages such as,

[0012] - The analyzer can be used to conveniently and quickly analyze diseases or foreign impurities (such as addictive substances or alcohol) in the body without causing difficulties or pain to the user because they do not need to go to the hospital to have blood drawn or urine collected;

[0013] - The analyzer can provide accurate results comparable to those obtained from blood draws or urine tests, which is particularly beneficial for the conditions of certain diseases, such as diabetes, where blood glucose needs to be regularly monitored. Since the breath gas analysis results obtained by the analyzer can conveniently and quickly provide information to patients, enabling them to pay timely attention to their conditions and take good care of themselves; and

[0014] - The analyzer can control the breath flow pattern to deliver gas and organic volatile molecule in an amount and ratio suitable for the sensor for analysis, so as to obtain effective analysis even when the concentration of gas and volatile molecule is low and the humidity is high. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Figure 1 Shows the components of a portable breath gas and volatile analyzer according to an exemplary embodiment of the present invention.

[0016] Figure 2 Is a side view of the breath input part of a portable breath gas and volatile analyzer according to an exemplary embodiment of the present invention.

[0017] Figure 3 Is a front view of the breath input part of a portable breath gas and volatile analyzer according to an exemplary embodiment of the present invention.

[0018] Figure 4 Is a rear view of the breath input part of a portable breath gas and volatile analyzer according to an exemplary embodiment of the present invention.

[0019] Figure 5 Is a bottom view of the breath input part of a portable breath gas and volatile analyzer according to an exemplary embodiment of the present invention.

[0020] Figure 6 Is a cross-sectional view of the main pipe of the breath flow regulating pipe of a portable breath gas and volatile analyzer according to an exemplary embodiment of the present invention.

[0021] Figure 7 Is a graph showing the analysis results of breath acetone gas with a concentration range of 0 to 9 ppm, where Figure 7 a shows the analysis results obtained using gas chromatography technology, and Figure 7 b shows the analysis results obtained using the portable breath gas and volatile analyzer according to the present invention.

[0022] Figure 8 Is a graph showing the change in the electrical signal from the sensor obtained using the portable breath gas and volatile analyzer according to the present invention in a clinical trial, regarding its ability to analyze breath acetone gas from a sample group. Detailed implementation mode

[0023] The portable breath gas and volatile substance analyzer according to the present invention will now be described in more detail with reference to the accompanying drawings.

[0024] Figures 1 to 6 An exemplary embodiment of the portable breath gas and volatile substance analyzer according to the present invention is shown. The portable breath gas and volatile substance analyzer includes a breath input part (1) for inputting breath into the analyzer by blowing, a breath delivery part (2) connected to the breath input part (1), a breath storage part (3) connected to the breath delivery part (2), a sensor (4) provided in the breath storage part (3) for detecting breath, and a microcontroller (5) connected to the sensor (4), the microcontroller (5) being configured to receive breath data from the sensor (4) to analyze data of gases and volatile substances.

[0025] According to the present invention, the breath input part (1) includes: a mouthpiece (1.1) having a breath input channel (1.1.1) for the user to blow; a breath flow adjustment tube (1.2) connected to the mouthpiece (1.1); and an end part (1.3) connected to the breath flow adjustment tube (1.2) and having a breath output channel (1.3.1). The breath flow adjustment tube (1.2) includes: a main tube (1.2.1) provided between the mouthpiece (1.1) and the end part (1.3) of the breath input part (1); and a breath delivery tube (1.2.2) arranged below the main tube (1.2.1) to serve as a channel for allowing breath to flow to the breath delivery part (2). The breath delivery tube (1.2.2) is arranged at a position 0.5 mm to 75 mm away from the mouthpiece (1.1) in the horizontal direction.

[0026] According to the above embodiment, delivering the breath into the breath input part (1) including the breath flow adjustment tube (1.2) (where the breath delivery tube (1.2.2) is installed in place to deliver the breath to the breath delivery part (2)) allows controlling the breath flow pattern, so as to deliver gas and volatile organic matter molecules in an appropriate amount and ratio. The excess breath can be discharged through the breath output channel (1.3.1).

[0027] In a preferred embodiment, the main pipe (1.2.1) is a pipe having an air flow channel (1.2.1.1) on the inner side. The end of the air flow channel (1.2.1.1) is on the side connected to the air output channel (1.3.1), and it tapers towards the air output channel (1.3.1). The main pipe (1.2.1) has a length of 15 mm to 80 mm, preferably 30 mm to 50 mm. The air delivery pipe (1.2.2) is arranged perpendicular to the horizontal axis of the main pipe (1.2.1).

[0028] Preferably, the air delivery pipe (1.2.2) is a hollow circular pipe with a diameter of 0.5 mm to 5 mm.

[0029] In an alternative embodiment, the manufacturing materials of the main pipe (1.2.1) and the air delivery pipe (1.2.2) can be selected from polyethylene, polypropylene, and polytetrafluoroethylene (Teflon), preferably polytetrafluoroethylene or polyethylene and polypropylene with an inner surface coated with polytetrafluoroethylene. These materials, especially polytetrafluoroethylene, are suitable for gas flow and corrosion resistance. They are also more effective than other materials in removing polluted gases.

[0030] According to a specific embodiment, the air input channel (1.1.1) is a hole with a diameter of 0.5 mm to 15 mm, and the air output channel (1.3.1) is a hole with a diameter of 0.5 mm to 5 mm.

[0031] Preferably, the mouthpiece (1.1), the air flow regulating pipe (1.2), and the end part (1.3) are connected in a detachable manner.

[0032] According to the present invention, the air delivery part (2) includes: an air receiving pipe (2.1) that is connected to the air delivery pipe (1.2.2) of the air flow regulating pipe (1.2); a pump (2.2) that is connected to the air receiving pipe (2.1) to control the air flow rate; and an air output pipe (2.3) that is connected to the pump (2.2) to deliver the air to the air storage part (3) in the area near the sensor (4).

[0033] Preferably, the pump (2.2) is separately installed near the air storage part (3). The pump (2.2) controls the air flow rate within the range of 0 L / min to 3 L / min.

[0034] According to the above embodiment, the air flow is controlled by the pump (2.2) so that the flow rate is constant and impacts the area near the sensor (4) at a speed suitable for the sensor response, which is neither too fast nor too slow, thus enabling the sensor to more effectively detect gases and volatile substances.

[0035] The pump (2.2) can operate intermittently or continuously. The intermittent operation time is from 0.06 minutes to 1 minute, and the continuous operation time is from 0.06 minutes to 10 minutes.

[0036] Alternatively, the air intake tube (2.1) and the air output tube (2.3) are made of silicone or polytetrafluoroethylene.

[0037] According to the present invention, the air storage part (3) includes: a storage chamber (3.1); an inlet (3.2) which is arranged above the storage chamber (3.1) to serve as a passage for the input of the air received from the air delivery part (2); and a moisture discharge port (3.3) which is arranged below the storage chamber (3.1).

[0038] According to a preferred embodiment, the storage chamber (3.1) has a volume of 0.10 liters to 3 liters, a cylindrical shape with a diameter of 15 mm to 35 mm, and a height of 30 mm to 70 mm.

[0039] By placing the inlet (3.2) above the storage chamber (3.1) and placing the sensor (4) at an appropriate height at the bottom of the storage chamber (3.1), the air flowing into the storage chamber (3.1) will not immediately contact the sensor (4); on the contrary, it will gradually flow into the storage chamber (3.1) at a controlled speed and spread to properly contact the sensor (4), so that the sensor can respond more efficiently to gases and volatile substances. In addition, the moisture discharge port (3.3) also helps to discharge the residual gas or moisture in the storage chamber (3.1) and prevent the condensation of water vapor in the system.

[0040] In one embodiment, the sensor (4) can be a metal oxide sensor dedicated to acetone gas, which makes the breath gas and volatile substance analyzer particularly suitable for indicating diabetes and blood sugar levels. In an alternative aspect, the sensor (4) can be a temperature sensor, a humidity sensor, or a combination thereof, to help improve the analysis efficiency of gases or volatile substances in terms of quality and quantity.

[0041] According to the present invention, the microcontroller (5) includes a processor (5.1) for processing the breath data obtained from the sensor (4), and a controller (5.2) for controlling the operation of the air delivery part (2). The processor (5.1) includes a feature generation part (5.1.1) and a calculation part (5.1.2), the feature generation part (5.1.1) is used to generate features according to the breath data signal detected by the sensor (4), and the calculation part (5.1.2) is used to process the features to obtain the disease identity.

[0042] As an example, the feature generation section (5.1.1) generates features based on the voltage data signal of the sensor (4), and the calculation section (5.1.2) operates using artificial neural networks and / or artificial intelligence methods.

[0043] To use the portable breath gas and volatile substance analyzer, the user blows their breath through the breath input section (1). Then, the breath flows into the main pipe (1.2.1) (shown in dashed lines in Figure 1 ), where a part of the breath to be analyzed continues to flow into the breath delivery pipe (1.2.2), while the other part of the excess breath is discharged through the breath output channel (1.3.1).

[0044] The breath to be analyzed flows from the breath delivery pipe (1.2.2) into the breath receiving pipe (2.1) and is transmitted to the breath output pipe (2.3). The flow rate is controlled by the pump (2.2).

[0045] The breath from the breath output pipe (2.3) is further transmitted to the storage chamber (3.1) located above the upper part of the sensor (4), and then impinges on the sensor (4), which specifically responds to the target gas or volatile substance molecules.

[0046] The signal specific to the target gas and volatile substance molecules in the breath received from the sensor (4) is transmitted to the microcontroller (5) and analyzed to identify features. Then, appropriate features are selected to analyze the amount of the target gas or volatile substance molecules. Then, a prediction model is created using artificial neural networks and / or artificial intelligence. The prediction model is used to calculate the amount of the target gas and volatile substance molecules in the breath.

[0047] In an additional embodiment, the portable breath gas and volatile substance analyzer according to the present invention may further include a display (6) (not shown in the figure), which is used to display the analysis results of the gas and volatile substances. The display (6) can be a display with or without a display monitor.

[0048] In addition, the portable breath gas and volatile substance analyzer according to the present invention may further include a housing (7) (not shown in the figure), which is provided to cover the portable breath gas and volatile substance analyzer such that the mouthpiece (1.1) of the breath input section (1) extends outward. The housing (7) is provided to prevent the internal components from being exposed to the environment and to improve the aesthetics of the analyzer.

[0049] Now, the comparison between the test results using the portable breath gas and volatile substance analyzer according to the present invention and the analysis results using standard techniques will be described.

[0050] This test measures the response of the sensor (4) of the analyzer according to the present invention to a gas by simulating the situation of breath acetone gas (i.e., low-concentration acetone gas in the range of 0 ppm to 9 ppm), and using acetone gas as the representative gas in the test. The response of the gas is compared with the response measured using a standard technique (i.e., gas chromatography technique).

[0051] Compared with the acetone gas concentration, the analysis result of breath acetone gas obtained using gas chromatography technique is shown as the area under the curve, as Figure 7 shown in a. Compared with the acetone gas concentration, the analysis result obtained using the analyzer according to the present invention is shown as the response of the sensor to the gas, as Figure 7 shown in b.

[0052] According to Figure 7 a and Figure 7 b, it is found that the response to acetone gas with a concentration of 9 ppm is at the highest level, and the response of the sensor to acetone gas decreases as the gas concentration decreases. In summary, the response to the gas is proportional to the concentration of acetone gas, which corresponds to the analysis result obtained using gas chromatography technique, and the lowest acetone gas concentration that causes a response is 0.5 ppm. This indicates that the analyzer according to the present invention can be used to analyze acetone gas with a concentration as low as 0.5 ppm.

[0053] The analysis result of acetone gas obtained using the gas and volatile matter analyzer according to the present invention is compared with the result obtained using gas chromatography technique, and the data from the figures in Figure 7 a and Figure 7 b are interpreted as method validation parameters, as shown in Table 1 below.

[0054] Table 1

[0055]

[0056]

[0057] The parameters shown in Table 1 above indicate that the acetone gas analysis performed using the analyzer according to the present invention provides a recovery value within the range of 80% to 120% of the analysis performed using the standard gas chromatography technique, which corresponds to the standard for evaluating the characteristics of a suitable analysis method according to the International Standards of the Association of Official Agricultural Chemists.

[0058] In addition, clinical trials were conducted to test the performance of the analyzer according to the present invention. A group of 76 people using the analyzer was divided into a control sample group and a diabetic ketoacidosis (DKA) sample group. The analyzer according to the present invention was used to measure the amount of breath acetone gas from the sample groups. Then, the response to the electrical signal was analyzed and calculated to create a graph reflecting the change in the electrical signal, as shown in Figure 8 as shown. A summary of the signal interpretation is provided in Table 2 below.

[0059] Table 2

[0060]

[0061]

[0062] It can be seen that the change in the electrical signal obtained from the analyzer according to the present invention corresponds to the level of breath acetone gas. There is a statistical difference (P value < 0.001) between the breath acetone levels of the DKA sample group and the control sample group. A receiver operating characteristic (ROC) curve can be plotted to select the best cut-off for sensitivity and specificity interpretation from the clinical trials of the analyzer according to the present invention.

[0063] The portable breath gas and volatile substance analyzer according to the present invention is not limited to the above embodiments and drawings. Any modifications or changes can be made. For example, the portable breath gas and volatile substance analyzer according to the present invention can be modified to be capable of detecting the identity of other diseases besides diabetes by adjusting the design or type of the sensor (4). For example, modifications or changes can also be made to measure the amount of volatile substances or gases to indicate addictive substances or alcohol in the blood. Such modifications or changes are still considered to be within the scope of the present invention.

[0064] Best Mode of the Invention

[0065] The best mode of the present invention is as described in the specific embodiments of the present invention.

Claims

1. A portable breath gas and volatile substance analyzer, the portable breath gas and volatile substance analyzer comprises: A breath input part (1), the breath input part (1) is used to input breath into the analyzer by blowing; A breath delivery part (2), the breath delivery part (2) is connected to the breath input part (1); A breath storage part (3), the breath storage part (3) is connected to the breath delivery part (2); A sensor (4), the sensor (4) is arranged in the breath storage part (3) and is used to detect the breath; and A microcontroller (5), the microcontroller (5) is connected to the sensor (4) and is used to receive breath data from the sensor (4) to analyze data of gases and volatile substances. It is characterized in that The breath input part (1) includes: a mouthpiece (1.1), the mouthpiece (1.1) has a breath input channel (1.1.1) for the user to blow; a breath flow adjustment tube (1.2), the breath flow adjustment tube (1.2) is connected to the mouthpiece (1.1); and an end part (1.3), the end part (1.3) is connected to the breath flow adjustment tube (1.2) and has a breath output channel (1.3.1). Wherein, the breath flow adjustment tube (1.2) includes: a main tube (1.2.1), the main tube (1.2.1) is arranged between the mouthpiece (1.1) and the end part (1.3) of the breath input part (1); and a breath delivery tube (1.2.2), the breath delivery tube (1.2.2) is arranged below the main tube (1.2.1) to be used as a channel allowing the breath to continue flowing to the breath delivery part (2), and the breath delivery tube (1.2.2) is arranged at a position 0.5 mm to 75 mm away from the mouthpiece (1.1) in the horizontal direction. The breath storage part (3) includes: a storage chamber (3.1); an inlet (3.2), the inlet (3.2) is arranged above the storage chamber (3.1) to be used as a channel for the input of the breath received from the breath delivery part (2); and a moisture discharge port (3.3), the moisture discharge port (3.3) is arranged below the storage chamber (3.1). The sensor (4) is placed at the bottom of the storage chamber (3.1) and the height range of the storage chamber (3.1) is 30 mm to 70 mm.

2. The portable breath gas and volatile substance analyzer according to claim 1, wherein The main tube (1.2.1) is a tube having a breath flow channel (1.2.1.1) on the inner side, and the end of the breath flow channel (1.2.1.1) is on the side connected to the breath output channel (1.3.1), and it tapers gradually towards the breath output channel (1.3.1).

3. The portable breath gas and volatile substance analyzer according to claim 1 or 2, wherein The main tube (1.2.1) has a length of 15 mm to 80 mm.

4. The portable breath gas and volatile substance analyzer according to claim 1 or 2, wherein, the main pipe (1.2.1) has a length of 30 mm to 50 mm.

5. The portable breath gas and volatile substance analyzer according to claim 1, wherein, the breath delivery pipe (1.2.2) is arranged perpendicular to the horizontal axis of the main pipe (1.2.1).

6. The portable breath gas and volatile substance analyzer according to claim 1 or 5, wherein, the breath delivery pipe (1.2.2) is a hollow circular pipe with a diameter of 0.5 mm to 5 mm.

7. The portable breath gas and volatile substance analyzer according to claim 1, wherein, the manufacturing materials of the main pipe (1.2.1) and the breath delivery pipe (1.2.2) are selected from polyethylene, polypropylene, and polytetrafluoroethylene.

8. The portable breath gas and volatile substance analyzer according to claim 1, wherein, the manufacturing materials of the main pipe (1.2.1) and the breath delivery pipe (1.2.2) are selected from polytetrafluoroethylene or polyethylene and polypropylene with an inner surface coated with polytetrafluoroethylene.

9. The portable breath gas and volatile substance analyzer according to claim 1, wherein, the breath input channel (1.1.1) is a hole with a diameter of 0.5 mm to 15 mm, and the breath output channel (1.3.1) is a hole with a diameter of 0.5 mm to 5 mm.

10. The portable breath gas and volatile substance analyzer according to claim 1, wherein, the mouthpiece (1.1), the breath flow adjustment pipe (1.2), and the end part (1.3) are connected in a detachable manner.

11. The portable breath gas and volatile substance analyzer according to claim 1, wherein, the breath delivery part (2) includes: a breath receiving pipe (2.1) which is connected to the breath delivery pipe (1.2.2) of the breath flow adjustment pipe (1.2); a pump (2.2) which is connected to the breath receiving pipe (2.1) to control the breath flow rate; and a breath output pipe (2.3) which is connected to the pump (2.2) to deliver the breath to the breath storage part (3) in the area near the sensor (4).

12. The portable breath gas and volatile substance analyzer according to claim 11, wherein, the pump (2.2) is separately installed near the breath storage part (3).

13. The portable breath gas and volatile substance analyzer according to claim 11 or 12, wherein, the pump (2.2) controls the breath flow rate within the range of 0 L / min to 3 L / min.

14. The portable breath gas and volatile substance analyzer according to claim 11 or 12, wherein, the pump (2.2) operates intermittently or continuously, wherein the intermittent operation time is 0.06 minutes to 1 minute, and the continuous operation time is 0.06 minutes to 10 minutes.

15. The portable breath gas and volatile substance analyzer according to claim 11, wherein, the manufacturing materials of the breath receiving tube (2.1) and the breath output tube (2.3) are silicone or polytetrafluoroethylene.

16. The portable breath gas and volatile substance analyzer according to claim 1, wherein, the storage chamber (3.1) has a volume of 0.10 liters to 3 liters.

17. The portable breath gas and volatile substance analyzer according to claim 1 or 16, wherein, the storage chamber (3.1) has a cylindrical shape with a diameter of 15 mm to 35 mm.

18. The portable breath gas and volatile substance analyzer according to claim 1, wherein, the sensor (4) is a metal oxide sensor dedicated to acetone gas.

19. The portable breath gas and volatile substance analyzer according to claim 1, wherein, the sensor (4) is a temperature sensor, a humidity sensor, or a combination thereof.

20. The portable breath gas and volatile substance analyzer according to claim 1, wherein, the microcontroller (5) includes a processor (5.1) for processing the breath data obtained from the sensor (4), and a controller (5.2) for controlling the operation of the breath delivery section (2).

21. The portable breath gas and volatile substance analyzer according to claim 20, wherein, the processor (5.1) includes a feature generation section (5.1.1) and a calculation section (5.1.2). The feature generation section (5.1.1) is configured to generate features based on the breath data signal detected by the sensor (4), and the calculation section (5.1.2) is configured to process the features to obtain a value indicating the disease identity.

22. The portable breath gas and volatile substance analyzer according to claim 21, wherein, the feature generation section (5.1.1) generates features based on the voltage data signal of the sensor (4).

23. The portable breath gas and volatile substance analyzer according to claim 21, wherein, the calculation section (5.1.2) operates using an artificial neural network.

24. The portable breath gas and volatile substance analyzer according to claim 21, wherein, the calculation section (5.1.2) operates using an artificial intelligence method.

25. The portable breath gas and volatile substance analyzer according to claim 1, further comprising a display (6), and the display (6) is configured to display the analysis results of the gas and volatile substances.

26. The portable breath gas and volatile substance analyzer according to claim 25, wherein, the display (6) is a display with or without a monitor.

27. The portable breath gas and volatile substance analyzer according to claim 1, further comprising a housing (7), and the housing (7) is configured to cover the portable breath gas and volatile substance analyzer such that the mouthpiece (1.1) of the breath input section (1) extends outward.

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