A centrally symmetrical dual-electrode structure for recording neural signals at the same site

Abstract

The present disclosure provides a centrally symmetrical dual-electrode structure capable of recording neural signals at the same site, comprising: a first recording electrode site for recording neural signals; a second recording electrode site, which is spirally staggered and spaced from the first recording electrode site, for recording neural signals at the same site recorded by the first recording electrode site; a first electrode trace, which is connected to the first recording electrode site, for transmitting the neural signals recorded by the first recording electrode site; and a second electrode trace, which is connected to the second recording electrode site, for transmitting the neural signals recorded by the second recording electrode site. The present disclosure also provides a signal recording device.

Description

Technical Field

[0001] The present disclosure relates to the field of brain-computer interface technology, and in particular to a centrally symmetrical dual-electrode structure capable of recording neural signals at the same site and a signal recording device. Background Art

[0002] In the field of invasive brain-computer interfaces, microelectrodes are often used to collect electrophysiological activity signals in the brain, especially high-frequency spike signals, which can reflect the activity of single or multiple neurons and have therefore received special attention. High-quality recording signals are the key to analyzing neuronal activity, and the quality of signal recording is closely related to the signal-to-noise ratio. Since neural microelectrodes are generally recorded extracellularly and due to the presence of background noise, the signal-to-noise ratio of the recorded signal is generally low.

[0003] One possible way to improve the signal-to-noise ratio is to arrange the electrodes at a high density so that multiple electrodes can record the signals of the same neuron, or to use concentric ring electrodes so that the inner and outer ring electrodes can record the neural signals at the same site. Then, through algorithm processing, similar neural signal components can be extracted and noise signal components can be suppressed, thereby improving the signal-to-noise ratio.

[0004] However, these electrode designs cannot record exactly the same signal at the same location. This is because the arrangement of these electrodes is not completely symmetrical for a certain location in space, and the neural signals they record differ in amplitude and phase, which may increase the difficulty of subsequent algorithms in signal processing, and thus have limited improvement in signal-to-noise ratio. Summary of the invention

[0005] In order to solve the above problems in the prior art, the present disclosure provides a centrally symmetrical dual-electrode structure that can record neural signals at the same site, so as to realize the collection of neural signals at the same site and improve the signal-to-noise ratio of the recorded signals.

[0006] The first aspect of the present disclosure provides a centrally symmetrical dual-electrode structure capable of recording neural signals at the same site, comprising: a first recording electrode site for recording neural signals; a second recording electrode site, which is spirally staggered and spaced apart from the first recording electrode site, for recording neural signals at the same site as recorded by the first recording electrode site; a first electrode trace, which is connected to the first recording electrode site, for transmitting the neural signals recorded by the first recording electrode site; and a second electrode trace, which is connected to the second recording electrode site, for transmitting the neural signals recorded by the second recording electrode site.

[0007] Furthermore, the first recording electrode site and the second recording electrode site (102) are spirally interlaced to form a centrally symmetrical structure.

[0008] Furthermore, the central symmetrical structure is maze-shaped or vortex-shaped.

[0009] Furthermore, the centrally symmetrical dual-electrode structure also includes: a first electrode pad, which is connected to the other end of the first electrode wiring and is used to connect the first electrode wiring to an external electronic device; a second electrode pad, which is connected to the other end of the second electrode wiring and is used to connect the second electrode wiring to an external electronic device.

[0010] Furthermore, the first recording electrode site and the second recording electrode site are made of a conductive material, and the layer thickness thereof is 100 nm to 200 nm.

[0011] Furthermore, the diameter range of the maze and vortex is 30 to 50 μm.

[0012] Furthermore, the external electronic device is a neural signal amplification chip or a signal recording system.

[0013] The second aspect of the present disclosure provides a signal recording device, comprising: at least one centrally symmetrical dual-electrode structure capable of recording neural signals at the same site provided by the first aspect of the present disclosure, wherein the centrally symmetrical dual-electrode structure capable of recording neural signals at the same site is used to record two neural signals at the same site; an external electronic device, which is electrically connected to the at least one centrally symmetrical dual-electrode structure capable of recording neural signals at the same site, and is used to perform algorithmic processing on the two neural signals to obtain processed neural signals.

[0014] Compared with the prior art, the present invention has at least the following beneficial effects:

[0015] (1) The centrally symmetrical dual-electrode structure adopts a maze-like or vortex-like design, in which two independent electrodes are arranged in a spiral and staggered manner so that they can be evenly and symmetrically distributed in space.

[0016] (2) The centrosymmetric dual-electrode structure adopts symmetrical and uniform distribution, which can record almost identical neural signals at the same spatial location.

[0017] (3) Based on the collected neural signals, the signal-to-noise ratio of the recorded signals can be greatly improved through algorithm processing. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] For a more complete understanding of the present disclosure and its advantages, reference will now be made to the following description taken in conjunction with the accompanying drawings, in which:

[0019] Figure 1 A schematic diagram of a centrally symmetrical dual-electrode structure capable of recording neural signals at the same site according to an embodiment of the present disclosure is shown;

[0020] Figure 2 A schematic diagram of a centrally symmetrical dual-electrode structure capable of recording neural signals at the same site according to another embodiment of the present disclosure is shown;

[0021] Description of reference numerals:

[0022] 101 - first recording electrode site, 102 - second recording electrode site, 103 - first electrode routing, 104 - second electrode routing, 105 - first electrode pad, 106 - second electrode pad, 100 - centrally symmetrical dual-electrode structure capable of recording neural signals at the same site. DETAILED DESCRIPTION

[0023] Hereinafter, embodiments of the present disclosure will be described with reference to the accompanying drawings. However, it should be understood that these descriptions are exemplary only and are not intended to limit the scope of the present disclosure. In the following detailed description, for ease of explanation, many specific details are set forth to provide a comprehensive understanding of the embodiments of the present disclosure. However, it is apparent that one or more embodiments may also be implemented without these specific details. In addition, in the following description, descriptions of known structures and technologies are omitted to avoid unnecessary confusion of the concepts of the present disclosure.

[0024] The terms used herein are only for describing specific embodiments and are not intended to limit the present disclosure. The terms "comprise", "include", etc. used herein indicate the existence of the features, steps, operations and / or components, but do not exclude the existence or addition of one or more other features, steps, operations or components.

[0025] All terms (including technical and scientific terms) used herein have the meanings commonly understood by those skilled in the art, unless otherwise defined. It should be noted that the terms used herein should be interpreted as having a meaning consistent with the context of this specification, and should not be interpreted in an idealized or overly rigid manner.

[0026] Based on the above technical problems, the present disclosure provides a centrally symmetrical dual-electrode structure that can record neural signals at the same site. The centrally symmetrical dual-electrode structure that can record neural signals at the same site achieves the goal of two independent electrodes recording almost identical neural signals at a certain site in space by staggering the dual electrodes and arranging them in a maze or vortex shape, and processing the recorded neural signals through an algorithm, thereby greatly improving the signal-to-noise ratio of the recorded signals.

[0027] Figure 1 The figure schematically shows a schematic diagram of a centrally symmetrical dual-electrode structure capable of recording neural signals at the same site according to an embodiment of the present disclosure.

[0028] like Figure 1As shown, the centrally symmetrical dual-electrode structure 100 capable of recording neural signals at the same site includes: a first recording electrode site 101, a second recording electrode site 102, a first electrode trace 103, a second electrode trace 104, a first electrode pad 105 and a second electrode pad 106.

[0029] In the embodiment of the present disclosure, the first recording electrode site 101 and the second recording electrode site 102 are arranged in a spiral, staggered and spaced relationship to record the neural signal at the same site.

[0030] Specifically, the first recording electrode site 101 and the second recording electrode site 102 are spirally interlaced to form a central symmetrical structure, and the two are independent of each other, with gaps between the lines and no intersections. Figure 1 As shown, the central symmetrical structure formed by the spiraling and interlacing of the first recording electrode site 101 and the second recording electrode site 102 is maze-like. Through this structural design, the two independent electrode sites are spiraled and interlaced together so that they are evenly and symmetrically distributed in space, so as to achieve the recording of almost completely consistent neural signals at the same spatial site.

[0031] In the embodiment of the present disclosure, one end of the first electrode trace 103 is connected to the first recording electrode site 101, and the other end is connected to the first electrode pad 105, for transmitting the neural signal recorded by the first recording electrode site 101 to the first electrode pad 105, and then outputting it to the external electronic device through the first electrode pad 105. Similarly, one end of the second electrode trace 104 is connected to the second recording electrode site 102, and the other end is connected to the second electrode pad 106, for transmitting the neural signal recorded by the second recording electrode site 102 to the second electrode pad 106, and then outputting it to the external electronic device through the second electrode pad 106.

[0032] According to an embodiment of the present disclosure, the external electronic device may be, for example, a neural signal amplification chip or a signal recording system, which is used to perform algorithmic processing on the signals collected by the centrally symmetrical dual-electrode structure, extract similar neural signal components, suppress noise signal components, and thus improve the signal-to-noise ratio of the recorded signal.

[0033] In the embodiment of the present disclosure, the diameter of the central symmetrical structure formed by the first recording electrode site 101 and the second recording electrode site 102 is in the range of 30 to 50 μm, and the line width is 3 to 5 μm. It should be noted that the smaller the line spacing between the first recording electrode site 101 and the second recording electrode site 102, the better, which is determined according to the realization process limit parameters, preferably 0.1 to 1 μm, and the embodiment of the present disclosure does not limit the line spacing between the first recording electrode site 101 and the second recording electrode site 102.

[0034] Furthermore, the first recording electrode site 101 and the second recording electrode site 102 are made of a conductive material, such as a composite material such as Cr / Au / Cr, and the layer thickness range is preferably 100nm to 200nm. In addition, the preparation material of the first electrode trace 103, the second electrode trace 104, the first electrode pad 105 and the second electrode pad 106 can be the same as the preparation material of the recording electrode site, and the embodiments of the present disclosure are not limited to this.

[0035] In the embodiment of the present disclosure, the shapes of the first electrode wiring 103 and the second electrode wiring 104 are not limited to the following: Figure 1 The square strip shape shown in the figure can be set according to actual application requirements, for example, it can also be a curved line shape. In addition, the shapes of the first electrode pad 105 and the second electrode pad 106 are not limited to the following. Figure 1 The square shape shown is only an exemplary description to facilitate the understanding of the technical solution of the present disclosure. The embodiment of the present disclosure does not limit the shapes of the first electrode wiring 103, the second electrode wiring 104, the first electrode pad 105 and the second electrode pad 106.

[0036] Figure 2 The figure schematically shows a schematic diagram of a centrally symmetrical dual-electrode structure capable of recording neural signals at the same site according to another embodiment of the present disclosure.

[0037] like Figure 2 As shown in the figure, the central symmetrical dual-electrode structure that can record neural signals at the same site is similar to Figure 1 The difference between the centrally symmetrical dual-electrode structure shown is that the centrally symmetrical structure formed by the spiral staggered first recording electrode site 101 and the second recording electrode site 102 is vortex-shaped, the dual-electrode structure is circular as a whole, and each electrode line is arranged in an arc-shaped staggered interval.

[0038] In the embodiments of the present disclosure, by swirling and interlacing the first recording electrode site 101 and the second recording electrode site 102 to form a vortex shape, the electrode line spacing between the first recording electrode site 101 and the second recording electrode site 102 can be made smaller, and the density of the two can be higher, so that the neural signal at the same site can be collected more accurately, thereby reducing signal errors and lowering the requirements of subsequent algorithms for signal processing, thereby improving the signal-to-noise ratio of the recorded signal.

[0039] It should be noted that if Figure 2 The first electrode trace 103, the second electrode trace 104, the first electrode pad 105 and the second electrode pad 106 in the central symmetrical double electrode structure for recording neural signals at the same site are similar to those in FIG. Figure 1 The connection relationship between the structures and components shown is consistent and will not be repeated in detail here.

[0040] The present invention provides a centrally symmetrical dual-electrode structure capable of recording neural signals at the same site. The centrally symmetrical dual-electrode structure capable of recording neural signals at the same site comprises dual electrodes which are spirally staggered and spaced in a maze-like or vortex-like manner, so that the dual electrodes are more closely distributed and the gap between them is further reduced, thereby improving the accuracy of dual-electrode recording of neural signals at the same site, reducing the difficulty of subsequent algorithm processing of the signal, and improving the signal-to-noise ratio of the recorded signal.

[0041] Another aspect of the embodiments of the present disclosure provides a signal recording device, comprising: at least one centrally symmetrical dual-electrode structure 100 capable of recording neural signals at the same site as shown in the above embodiments, the centrally symmetrical dual-electrode structure 100 capable of recording neural signals at the same site is used to record two neural signals at the same site. An external electronic device, which is electrically connected to the at least one centrally symmetrical dual-electrode structure capable of recording neural signals at the same site, is used to perform algorithmic processing on the two neural signals to obtain processed neural signals.

[0042] It should be noted that the specific structure and specific design parameters of the centrosymmetric dual-electrode structure 100 in the signal recording device are as shown in the above embodiment and will not be described in detail here.

[0043] While the disclosure has been illustrated and described in detail in the drawings and foregoing description, such illustration and description are to be considered illustrative or exemplary and not restrictive.

[0044] It will be appreciated by those skilled in the art that the features described in the various embodiments and / or claims of the present disclosure may be combined and / or combined in a variety of scopes, even if such combinations or combinations are not explicitly described in the present disclosure. In particular, the features described in the various embodiments and / or claims of the present disclosure may be combined and / or combined in a variety of scopes without departing from the spirit and teachings of the present disclosure. All of these combinations and / or combinations fall within the scope of the present disclosure.

[0045] Although the present disclosure has been shown and described with reference to specific exemplary embodiments of the present disclosure, it should be understood by those skilled in the art that various changes in form and details may be made to the present disclosure without departing from the spirit and scope of the present disclosure as defined by the appended claims and their equivalents. Therefore, the scope of the present disclosure should not be limited to the above-mentioned embodiments, but should be determined not only by the appended claims, but also by the equivalents of the appended claims.

Claims

1. A centrally symmetrical dual-electrode structure capable of recording neural signals at the same site, characterized in that: include: A first recording electrode site (101) for recording neural signals; A second recording electrode site (102) is arranged in a spirally interlaced manner with the first recording electrode site (101) and at intervals, and is used to record the neural signal at the same site recorded by the first recording electrode site (101); wherein the first recording electrode site (101) and the second recording electrode site (102) form a centrally symmetrical structure; wherein the centrally symmetrical structure is maze-shaped or vortex-shaped, and the spacing between the first recording electrode site (101) and the second recording electrode site (102) is 0.1 μm to 1 μm; A first electrode trace (103), which is connected to the first recording electrode site (101) and is used to transmit the neural signal recorded by the first recording electrode site (101); A second electrode trace (104) is connected to the second recording electrode site (102) and is used to transmit the neural signal recorded by the second recording electrode site (102).

2. The centrosymmetric dual-electrode structure capable of recording neural signals at the same site according to claim 1, characterized in that: The central symmetric dual-electrode structure also includes: A first electrode pad (105), connected to the other end of the first electrode wiring (103), and used to connect the first electrode wiring (103) to an external electronic device; A second electrode pad (106) is connected to the other end of the second electrode wiring (104) and is used to connect the second electrode wiring (104) to an external electronic device.

3. The centrosymmetric dual-electrode structure capable of recording neural signals at the same site according to claim 1, characterized in that: The first recording electrode site (101) and the second recording electrode site (102) are made of a conductive material, and the layer thickness thereof is 100nm-200nm.

4. The centrosymmetric dual-electrode structure capable of recording neural signals at the same site according to claim 1, characterized in that: The diameter range of the maze shape and the vortex shape is 30 μm to 50 μm.

5. The centrosymmetric dual-electrode structure capable of recording neural signals at the same site according to claim 2, characterized in that: The external electronic device is a neural signal amplification chip or a signal recording system.

6. A signal recording device, characterized in that: include: At least one centrally symmetrical dual-electrode structure capable of recording neural signals at the same site as claimed in any one of claims 1 to 5, wherein the centrally symmetrical dual-electrode structure capable of recording neural signals at the same site is used to record two neural signals at the same site; An external electronic device is electrically connected to at least one centrally symmetrical dual-electrode structure capable of recording neural signals at the same site, and is used to perform algorithmic processing on the two neural signals to obtain processed neural signals.

Images