Automatic alignment device and method based on artificial intelligence

Through the automatic alignment device based on artificial intelligence, the sensors and driving components are used to realize the precise alignment of upper and lower module components and the positioning and heating of chips, which solves the problems of inflexible alignment and insufficient accuracy in the prior art, and improves processing Accuracy and convenience.

CN115646669BActive Publication Date: 2024-12-20GUANGZHOU DEAOU MEDICAL TECH CO LTD
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Patent Information

Application Number
CN202211260200.1
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2022-10-14
Publication Date
2024-12-20
Estimated Expiration
2042-10-14

AI Technical Summary

Technical Problem

In the prior art, the upper module components and the lower module components cannot achieve specific position connection or control of the rotating components in the cavity, and the upper module components cannot adjust the position, limiting the flexibility and accuracy of alignment.

Method used

Using an automatic alignment device based on artificial intelligence, real-time position data of module components is obtained through the first and second sensors, the processor calculates the relative angle, and generates control commands to adjust the state of module components, and uses the driving components to achieve accurate alignment, including Centrifugal module assembly and rail assembly, thermal cover assembly and turntable assembly, use magnets and nozzle suction cups to enable chip positioning and heating.

Benefits of technology

Accurate alignment of upper and lower module components, avoid winding problems, simplify processing technology, improve processing accuracy, reduce calibration requirements, ensure correct positioning and heating effect of the chip, improve positioning and convenience of use .

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Abstract

The present invention discloses an automatic alignment device and method based on artificial intelligence, comprising: a first sensor coupled to an upper module component, used to obtain first real-time position data of a first preset point in the upper module component; a second sensor coupled to a lower module component, used to obtain second real-time position data of a second preset point in the lower module component; a processor, used to obtain the relative angle between the first preset point and the second preset point based on the first real-time position data and the second real-time position data, and capable of generating a control command for adjusting the state of the upper module component and / or the lower module component.
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Description

Technical Field

[0001] The present invention relates to the field of alignment technology, and in particular to an automatic alignment device and method based on artificial intelligence. Background Art

[0002] In the prior art, the aligned upper module assembly and the lower module assembly are fixed parts, the upper module assembly cannot adjust the position, and can only achieve a simple cavity closing process of the upper and lower module assemblies, and cannot achieve the connection or control function of the specific position of the rotating part in the cavity on the upper module assembly. Therefore, the present application aims to provide an automatic alignment device and method based on artificial intelligence that can overcome the above defects. Summary of the invention

[0003] The purpose of the present invention is to overcome the shortcomings of the prior art and provide an automatic alignment device and method based on artificial intelligence.

[0004] The objective of the present invention is achieved through the following technical solutions: an automatic alignment device based on artificial intelligence, comprising: a first sensor coupled to an upper module assembly, for obtaining first real-time position data of a first preset point in the upper module assembly; a second sensor coupled to a lower module assembly, for obtaining second real-time position data of a second preset point in the lower module assembly; a processor, for obtaining the relative angle between the first preset point and the second preset point based on the first real-time position data and the second real-time position data, and capable of generating a control command for adjusting the state of the upper module assembly and / or the lower module assembly.

[0005] Preferably, it also includes: a first drive component coupled to the upper module component, used to adjust the state of the upper module component; a second drive component coupled to the lower module component, used to adjust the state of the lower module component; the first drive component and / or the second drive component can operate based on the control command so that the relative angle is adjusted to a state less than a set threshold.

[0006] Preferably, the lower module assembly includes a centrifugal module assembly and a first slide rail assembly, the centrifugal module assembly includes a centrifugal motor mounting plate, a centrifugal motor and a turntable assembly, the centrifugal motor is arranged on the centrifugal motor mounting plate, and the turntable assembly is connected to the centrifugal motor, wherein the centrifugal motor can drive the turntable assembly to rotate based on the control command to change the state of the lower module assembly.

[0007] Preferably, the upper module assembly includes a thermal cover assembly and a second slide rail assembly, the thermal cover assembly includes a sleeve and a heating disk nested in the sleeve, a thermal cover guide column is provided on the heating disk, wherein when the thermal cover assembly moves toward the centrifugal module assembly, the thermal cover guide column can abut against and contact the turntable assembly.

[0008] Preferably, the turntable assembly comprises a turntable and a high temperature resistant magnet disposed on the turntable, the turntable is detachably connected with a plastic chip assembly, and the plastic chip assembly is provided with an iron sheet that can be adsorbed by the high temperature resistant magnet.

[0009] Preferably, the plastic chip assembly comprises a plastic chip and a plurality of positioning holes arranged on the plastic chip, the turntable is provided with a plurality of positioning posts, the positioning posts can be nested in the positioning holes, wherein when the thermal cover assembly moves toward the centrifugal module assembly, the thermal cover guide posts can be nested in the positioning holes.

[0010] Preferably, the heat cover assembly also includes a heating film, a bakelite cover and a thermal insulation cotton tube, the bakelite cover is nested in the sleeve, the heating film is arranged in the sleeve in a manner of being located between the bakelite cover and the heating plate, and the sleeve can be nested in the thermal insulation cotton tube.

[0011] Preferably, the heat cover assembly is provided with a first channel assembly and a second channel assembly, and the first channel assembly and the second channel assembly both include an air nozzle seat and an air nozzle suction cup, the air nozzle seat is provided on the thermal insulation cotton cylinder, and the air nozzle suction cup is provided on the heating plate.

[0012] An automatic alignment method based on artificial intelligence includes the following steps: configuring a first sensor coupled to an upper module assembly to obtain first real-time position data of a first preset point in the upper module assembly; configuring a second sensor coupled to a lower module assembly to obtain second real-time position data of a second preset point in the lower module assembly; configuring a processor to obtain the relative angle between the first preset point and the second preset point based on the first real-time position data and the second real-time position data, and generating a control command for adjusting the state of the upper module assembly and / or the lower module assembly.

[0013] Preferably, the following steps are also included: configuring a first drive component coupled to the upper module component for adjusting the state of the upper module component; configuring a second drive component coupled to the lower module component for adjusting the state of the lower module component; the first drive component and / or the second drive component operates based on the control command so that the relative angle is adjusted to a state less than a set threshold.

[0014] The present invention has the following advantages:

[0015] (1) The upper module assembly for alignment is a movable part, and a slip ring is used as a connecting part between the movable part and the outside. While the upper and lower module assemblies are closed by the receptor, the upper module assembly can rotate synchronously with the rotating parts; an angle sensor or encoder is used to realize the positioning of the upper module assembly, and an optical coupler and motor control are used to realize the positioning of the lower module assembly, so as to realize the precise alignment of the upper and lower module assemblies. As long as the calibration work is completed before leaving the factory, there is no need for re-calibration during the customer's use, and the device can automatically complete the alignment operation; an electrical control component can be added to the upper module assembly to control the specific position of the chip in the cavity (this design is to control the gas valve of the chip), and there will be no winding problems.

[0016] (2) An electrical control component can be added to the upper module assembly to control the specific position of the chip in the cavity (this design is to control the gas valve of the chip), and during this control process, the upper module assembly can be rotated at will. When the upper wooden module assembly is rotated at will, there will be no winding problem.

[0017] (3) The structural design of the turntable can simplify the machining process and better ensure its machining accuracy. After being assembled with the rotating shaft, the levelness of the turntable surface can be better guaranteed (the turntable circular hole and the turntable surface can be processed on the lathe in one clamping, ensuring the accuracy of the parts). Ultimately, no calibration operation is required after leaving the factory.

[0018] (4) In the present application, a second countersunk hole and a step are provided at the center of the upper surface of the plastic chip (the bottom circular hole inside the chip is slightly larger than the diameter of the high temperature resistant magnet and smaller than the diameter of the metal sheet), and then the metal sheet is embedded in the second countersunk hole (the metal sheet and the second countersunk hole do not need to have a tolerance matching relationship, and the metal sheet will not fall off or the chip will be deformed due to assembly when the chip is heated or frozen), the thickness of the metal sheet is less than or equal to the depth of the second countersunk hole, and more than two positioning holes are designed away from the center of the chip (the closer the positioning hole is to the reaction detection hole, the better, so that the position offset of the detection hole can be reduced), and the positions of the positioning holes are not on the same circumference and the same angle. At the same time, a high temperature resistant magnet is installed in the center of the turntable. When the chip is placed on the turntable, the magnetic attraction generates pressure on the metal sheet by adsorbing the metal sheet to press the chip tightly. The position of the turntable away from the center corresponds to the design of multiple positioning columns that match the chip. This method can effectively prevent the chip from being placed upside down. If it is not placed right side up, the chip will be lifted up by the positioning column and the bottom of the chip cannot fit the turntable, which has an anti-mistake effect; the positioning hole far away from the center has a smaller offset than the positioning hole set at the center position, which effectively improves the positioning accuracy and ensures the performance of fluorescence detection; the magnetic adsorption and clamping method has a simple structural design, low cost, convenient chip replacement, and saves time. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 It is a structural schematic diagram of an automatic alignment device based on artificial intelligence of the present invention;

[0020] Figure 2 is a schematic diagram of the structure of the automatic alignment device from another perspective;

[0021] Figure 3 is a schematic structural diagram of a centrifugal module assembly;

[0022] Figure 4 It is a structural schematic diagram of a plastic chip assembly;

[0023] Figure 5 is a schematic diagram of the structure of the turntable assembly;

[0024] Figure 6 is a schematic diagram of the structure of the turntable assembly from another perspective;

[0025] Figure 7 is a schematic diagram of the structure of the thermal cover assembly;

[0026] Figure 8 A schematic diagram of the modular connection between the processor and each electronic module.

[0027] In the figure, 1-upper module assembly, 2-lower module assembly, 3-mounting base plate, 1a-heat cover assembly, 1b-second slide rail assembly, 2a-centrifugal module assembly, 2b-first slide rail assembly, 2b-1-sliding support plate, 2b-2-first guide rail, 2b-3-in and out warehouse motor, 4-out warehouse photoelectric sensor, 5-in warehouse photoelectric sensor, 6-in and out warehouse photoelectric sensor sheet, 1b-1-mounting plate, 1b-2-second guide rail, 1b-3-lifting screw motor, 7-fixing bracket, 8-upper photoelectric sensor, 9-lower photoelectric sensor, 10-lifting photoelectric sensor sheet, 2a-1 centrifugal motor mounting plate, 2a-2-centrifugal motor, 2a-3-turntable assembly, 2a-4-plastic chip assembly, 11-first side, 12-second side, 13-turntable, 14-magnet mounting seat, 15-high temperature resistant magnet, 16-first countersunk hole, 17-mounting groove, 18 -connecting sleeve, 19-key slot, 20-first slot, 18a-first section, 18b-second section, 21-second slot, 18b-1-first end, 18b-2-second end, 22-turntable reset photoelectric sensor, 23-turntable reset photoelectric sensor, 24-positioning column, 25-positioning hole, 26-plastic chip, 27-iron sheet, 28-sealing film, 29-second countersunk hole, 30-first channel component, 31- The second channel assembly, 31a-air nozzle seat, 31b-air nozzle suction cup, 32-sleeve, 33-heating plate, 34-heating film, 35-bakelite cover, 36-insulating cotton tube, 37-first cavity, 38-second cavity, 39-bolt hole, 40-bolt, 41-hot cover guide column, 42-first sensor, 43-second sensor, 44-processor, 45-first drive assembly, 46-second drive assembly, 47-rotating shaft. DETAILED DESCRIPTION

[0028] The present invention is further described below in conjunction with the accompanying drawings, and the protection scope of the present invention is not limited to the following:

[0029] like Figures 1 to 8 As shown, the present application provides an automatic alignment device based on artificial intelligence, including an upper module component 1, a lower module component 2 and a mounting substrate 3. The upper module component 1 and the lower module component 2 are both arranged on the mounting substrate 3. The lower module component 2 is used to place a microfluidic chip and drive the microfluidic chip to rotate so that the microfluidic chip can be centrifuged. The upper module component 1 is used to heat the microfluidic chip.

[0030] Preferably, the lower module assembly 2 includes a centrifugal module assembly 2a and a first slide assembly 2b. The first slide assembly 2b is arranged on the mounting substrate 3, and the centrifugal module assembly 2a can be coupled to the first slide assembly 2b, so that the centrifugal module assembly 2a can move along the first slide assembly 2b. The upper module assembly 1 includes a thermal cover assembly 1a and a second slide assembly 1b. A support frame 5 is arranged on the mounting substrate 3, and the second slide assembly 1b is arranged on the support frame 5. The thermal cover assembly 1a is coupled to the second slide assembly 1b, so that the thermal cover assembly 1a can move along the extension direction of the second slide assembly 1b. For example, the centrifugal module assembly 2a can move in the horizontal direction, and the thermal cover assembly can move in the vertical direction. After the centrifugal module assembly 2a moves, it can be located directly below the thermal cover assembly. When in use, after the centrifugal module assembly 2a moves in the horizontal direction, it can be removed from directly below the thermal cover assembly 1a, so as to facilitate the placement of a microfluidic chip on the centrifugal module assembly 2a. After the microfluidic chip is placed, the centrifugal module assembly 2a is moved to the bottom of the thermal cover assembly 1a, and the thermal cover assembly 1a is moved downward to contact with the microfluidic chip, thereby heating the microfluidic chip.

[0031] Preferably, the first slide rail assembly 2b includes a sliding support plate 2b-1, a first guide rail 2b-2 and an in-and-out motor 2b-3. The centrifugal module assembly 2a is arranged on the sliding support plate 2b-1, and the first guide rail 2b-2 is arranged on the mounting base plate 3. The first guide rail 2b-2 can be in a straight line. The sliding support plate 2b-1 can be connected to the first guide rail 2b-2 so as to be able to move along the extension direction of the first guide rail 2b-2. For example, the cross section of the first guide rail 2b-2 can be T-shaped, and a slot with a T-shaped cross-sectional shape is provided on the sliding support plate 2b-1, and the guide rail can be nested in the slot, so that the sliding support plate 2b-1 can be connected to the first guide rail 2b-2. The in-and-out motor 2b-2 is arranged on the mounting base plate 3 and coupled with the sliding support plate 2b-1, so that the sliding support plate 2b-1 can be driven to slide along the extension direction of the guide rail through the work of the in-and-out motor 2b-2. For example, a driving gear is connected to the rotating shaft of the in-and-out motor 2b-2, and a rack is provided on the sliding support plate 2b-1, which can be meshed with the driving gear. When the driving gear rotates clockwise, the sliding support plate 2b-1 can be driven to move in a first direction through the meshing of the rack, and when the driving gear rotates counterclockwise, the sliding support plate 2b-1 can be driven to move in a second direction through the meshing of the rack. The first direction and the second direction are opposite to each other. The first direction can be a direction toward the in-and-out motor 2b-2. The second direction can be a direction away from the in-and-out motor 2b-2.

[0032] Preferably, an exit photoelectric sensor 4 and an entry photoelectric sensor 5 are provided on the mounting substrate 3. An entry / exit photoelectric sensing sheet 6 is provided on the sliding support plate 2b-1. The connection line of the exit photoelectric sensor 4 and the entry photoelectric sensor 5 can be parallel to the first guide rail 2b-2. When the lower module assembly 2 is located directly below the upper module assembly 1, the entry / exit photoelectric sensing sheet 6 can be aligned with the entry photoelectric sensor 5. At this time, the entry photoelectric sensor 5 will intuitively display the position of the lower module assembly 2 by, for example, lighting up the indicator light. When the lower module assembly 2 is located directly below the upper module assembly 1, the entry / exit photoelectric sensing sheet can be aligned with the exit photoelectric sensor. At this time, the exit photoelectric sensor will intuitively display the position of the lower module assembly 2 by, for example, lighting up the indicator light.

[0033] Preferably, the second slide rail assembly 1b includes a mounting plate 1b-1, a second guide rail 1b-2 and a lifting screw motor 1b-3. A fixed bracket 7 is provided on the mounting base plate 3. The lifting screw motor 1b-3 is provided on the fixed bracket 7. The second guide rail 1b-2 is provided on the fixed bracket 7. The mounting plate 1b-1 is coupled to the second guide rail 1b-2 so that the mounting plate 1b-1 can move along the extension direction of the second guide rail 1b-2. The coupling direction between the mounting plate 1b-1 and the second guide rail 1b-2 is the same as the coupling mode between the sliding support plate and the first guide rail, which will not be repeated here. The lifting screw motor 1b-3 can be connected to the mounting plate 1b-1, and then when the lifting screw motor 1b-3 is working, it can drive the mounting plate 1b-1 to move up and down. An upper photoelectric sensor 8 and a lower photoelectric sensor 9 are provided on the fixed bracket 7. A lifting photoelectric sensor sheet 10 is provided on the mounting plate 1b. In the initial state, the upper module assembly 1 and the lower module assembly 2 are in a separated state, at which time, the lifting photoelectric sensing sheet 10 is aligned with the upper photoelectric sensor 8, so that the upper photoelectric sensor 8 can intuitively display the position of the upper module assembly 1 by, for example, lighting up an indicator light. When the upper module assembly 1 moves downward to abut against the lower module assembly 2, the lifting photoelectric sensing sheet 10 can be aligned with the lower photoelectric sensor 9, so that the lower photoelectric sensor 9 can intuitively display the position of the upper module assembly 1 by, for example, lighting up an indicator light.

[0034] Preferably, the centrifugal module assembly 2a includes a centrifugal motor mounting plate 2a-1, a centrifugal motor 2a-2, a connecting and fixing assembly 3 and a plastic chip assembly 2a-4. The centrifugal motor mounting plate 2a-1 can be in the shape of a flat plate, on which screw holes can be provided, and the centrifugal motor 2a-2 can be mounted and fixed on the first side 11 of the centrifugal motor mounting plate 2a-1 by screws. The turntable assembly 2 can be connected to the centrifugal motor 2a-2, and when the centrifugal motor 2a-2 is powered on, the turntable assembly 2 can rotate. The plastic chip assembly 2a-4 can be connected to the turntable assembly 2a-3, and can rotate synchronously with the turntable assembly 2a-3. The turntable assembly 2a-3 and the plastic chip assembly 2a-4 are both located on the second side 12 of the centrifugal motor mounting plate 2a-1. The first side 11 and the second side 12 are opposite to each other, for example, as Figure 3 As shown, the first side 11 may be the lower side of the centrifugal motor mounting plate 2a - 1 , and the second side 12 may be the upper side of the centrifugal motor mounting plate 2a - 1 .

[0035] Preferably, the turntable assembly 2a-3 includes a turntable 13, a magnet mounting seat 14 and a high temperature resistant magnet 15. A first countersunk hole 16 is provided on the turntable 13. The magnet mounting seat 14 can be nested in the first countersunk hole 16 and can be connected and fixed by a connecting member such as a bolt. A mounting groove 17 is provided on the magnet mounting seat 14, and the high temperature resistant magnet 15 can be placed in the mounting groove 17 and connected and fixed by a connecting member such as a bolt. A connecting sleeve 18 is provided on the turntable 13, and the connecting sleeve 18 can be in the shape of a hollow cylinder, so that the rotating shaft of the centrifugal motor 2a-2 can be inserted into the connecting sleeve 18. A keyway 19 is provided on the inner wall of the connecting sleeve 18, and the keyway 19 can extend along the axial direction of the connecting sleeve 18. A block may be provided on the rotating shaft of the centrifugal motor 2a-2. When the rotating shaft is inserted into the connecting sleeve 18, the block can be nested in the keyway 19. The cooperation between the keyway and the block can ensure that the rotating disk and the rotating shaft will not slip when the rotating disk rotates at high speed. A first slot 20 is also provided on the connecting sleeve 18 to separate the connecting sleeve 18 into a first section 18a and a second section 18b. The first section 18a is connected to the rotating disk 13, and a second slot 21 is provided on the second section 18b. The second slot 21 can completely cut off the second section 18b, so that the second section 18b has a first end 18b-1 and a second end 18b-2. Bolt holes may be provided on the first end 18b-1 and the second end 18b-2, and bolts may be provided in the bolt holes, so that the clamping force between the second section 18b and the rotating shaft can be increased by tightening the bolts. The first slot and keyway are provided on the connecting sleeve to ensure the concentricity with the power shaft. The lower part of the first slot is used for clamping, and the keyway can ensure that there is no slipping during high-speed rotation. This structure not only meets the requirements of ensuring installation accuracy, but also has the clamping function in one part; it is more convenient to install, and can be locked with one screw, and the operation can be easily completed with one hand. In addition, combined with the accuracy requirements, the structural design of the turntable can simplify the machining process and better ensure its machining accuracy, and better ensure the levelness of the turntable surface after assembly with the rotating shaft (the processing of the turntable round hole and the turntable surface can be completed on the lathe with one clamping, ensuring the accuracy of the parts).

[0036] Preferably, the second section 18b may be connected and fixed with a turntable reset photoelectric sensor sheet 22 by a bolt or other connecting member. A turntable reset photoelectric sensor 23 is provided on the centrifugal motor mounting plate 2a-1. The turntable reset photoelectric sensor 23 has a mounting seat with a C-shaped cross-section, a laser generator may be provided at the upper end of the mounting seat, and a receiver may be provided at the lower end of the mounting seat. When the turntable reset photoelectric sensor sheet 22 is located between the upper end and the lower end of the mounting seat, it can block the laser generated by the laser generator, and the receiver will not be able to receive the laser at this time, so that it can be determined that the turntable is in a reset state.

[0037] Preferably, a plurality of positioning posts 24 are provided on the turntable 13. Corresponding positioning holes 25 are provided on the plastic chip components 2a-4, so that the positioning posts 24 can be nested in the positioning holes 25. The placement of the plastic chip components has a foolproof effect, and the structural design can ensure the verticality, concentricity, and horizontality of the turntable and the rotating shaft, so that the plastic chip components will not jump or fly out during high-speed centrifugal motion.

[0038] Preferably, the plastic chip assembly 2a-4 includes a plastic chip 26, an iron sheet 27 and a sealing film 28. The plastic chip 26 and the turntable 13 can both be disc-shaped, and the diameters of the plastic chip 26 and the turntable 13 are the same. A second countersunk hole 29 is provided on the plastic chip 26. The iron sheet 4c can be disc-shaped, so that the iron sheet 4c can be placed in the second countersunk hole 29. The sealing film 28 can be attached to the iron sheet 27 and the plastic chip 26, and can then seal the second countersunk hole 29, so that when the plastic chip 26 is taken forward and backward, the iron sheet 4c in the second countersunk hole 29 will not fall off. The plastic chip assembly 2a-4 and the turntable assembly 2a-3 can be proportionally connected and pressed by the mutual adsorption of the high temperature resistant magnet 15 and the iron sheet 27. Specifically, as Figure 3As shown, when in use, the turntable 13 is placed with its first countersunk hole 16 facing upward, and the plastic chip 26 is placed with its second countersunk hole 29 facing upward. After rotating the plastic chip 26 so that the positioning hole 25 is aligned with the positioning post 24, the plastic chip 26 is moved downward so that the plastic chip 26 moves toward the turntable 13 until the positioning post 24 is fully inserted into the positioning hole 25. Due to the limitation of the positioning post 24 and the positioning hole 25, the plastic chip 26 and the turntable 13 will not rotate relative to each other. Finally, the iron sheet 27 is placed in the second countersunk hole 29, and the high temperature resistant magnet 15 and the iron sheet 27 will produce mutual adsorption, so that the iron sheet 27 can apply a pressing force to the plastic chip 26, thereby achieving the connection and fixation of the plastic chip 26 and the turntable 13. In the prior art, a polygonal hole is provided in the center of the plastic chip, and then a notch is provided on one of the sides for locating the origin of the chip; a polygonal and notched boss corresponding to the chip is designed on the top of the turntable, and the turntable boss and the polygonal hole in the center of the chip are placed flat on the turntable through a clearance fit, and the bottom of the chip fits with the upper surface of the turntable. Because the chip also needs to be centrifuged by rotating the turntable, a chip clamping device needs to be added to this device. This chip positioning and fixing method must ensure that the sample port of the chip faces upward, and cannot have a fool-proof effect on the front and back of the chip, which can easily cause misplacement and lead to experimental failure. Secondly, there is a gap between the polygonal hole in the center of the chip and the boss in the center of the turntable. Even if the gap in the center is very small, the offset of the detection port position away from the center corresponding to the bottom detection hole is also large, and inaccurate position accuracy will affect the results of fluorescence detection. At the same time, the additional clamping device due to centrifugation makes the structure complicated, the operation complicated, and the cost increased. In the present application, a second countersunk hole and a step are provided at the center of the upper surface of the plastic chip (the bottom circular hole inside the chip is slightly larger than the diameter of the high temperature resistant magnet and smaller than the diameter of the metal sheet), and then the metal sheet is embedded in the second countersunk hole (the metal sheet and the second countersunk hole do not need to have a tolerance matching relationship, and the metal sheet will not fall off or the chip will be deformed due to assembly when the chip is heated or frozen), the thickness of the metal sheet is less than or equal to the depth of the second countersunk hole, and more than two positioning holes are designed outside the center away from the chip (the closer the positioning hole is to the reaction detection hole, the better, so that the position offset of the detection hole can be reduced), and the positions of the positioning holes are not on the same circumference and the same angle. At the same time, a high temperature resistant magnet is installed in the center of the turntable. When the chip is placed on the turntable, the magnetic attraction generates pressure on the metal sheet by adsorbing the metal sheet to press the chip. The position of the turntable away from the center corresponds to the design of multiple positioning columns that match the chip. This method can effectively prevent the chip from being placed upside down. If it is not placed right side up, the chip will be lifted up by the positioning column and the bottom of the chip cannot fit the turntable, which has an anti-mistake effect; the positioning hole far away from the center has a smaller offset than the positioning hole set at the center position, which effectively improves the positioning accuracy and ensures the performance of fluorescence detection; the magnetic adsorption and clamping method has a simple structural design, low cost, convenient chip replacement, and saves time.

[0039] Preferably, the outer contour shape of the thermal cover assembly 1a can be defined by a circle, and the thermal cover assembly 1a is provided with a first airflow channel assembly 30 and a second airflow channel assembly 31 which are symmetrical to each other about the center of the circle of the thermal cover assembly 1a, wherein the first airflow channel assembly 30 and the second airflow channel assembly 31 both include an air nozzle seat 31a and an air nozzle suction cup 31b. The first airflow channel 3 and the second airflow channel 4 can both be connected to an air pump. When in use, the air pump can pump air so that the air nozzle suction cup 31b can produce a negative pressure effect. After the air nozzle suction cup 31b is in contact with the microfluidic chip, the air nozzle suction cup 31b can adsorb it, thereby ensuring that the microfluidic chip can fit tightly with the thermal cover assembly 1a, thereby achieving a better heating effect.

[0040] Preferably, the thermal cover assembly 1a includes a sleeve 32, a heating plate 33, a heating film 34 and a bakelite cover 35, the sleeve 32 is in a hollow cylindrical shape, the heating plate 33 is nested in the sleeve 32 to separate the inner cavity of the sleeve 32 into a first cavity 37 and a second cavity 38, wherein the heating film 34 and the bakelite cover 35 are both nested in the first cavity 37. Specifically, a plurality of bolt holes 39 are provided on the side wall of the first cavity 37, and the bakelite cover 35 can be connected to the bolt 40 when the bolt hole 39 is nested with a bolt 40. That is, the bakelite cover 35 can be fixed on the sleeve 32 by bolts. The heating film 34 is arranged between the bakelite cover 35 and the heating plate 33. The heating film 34 can generate heat after being energized, and the heat can be transferred to the heating plate 33, so that the temperature of the heating plate 33 can be increased, and then when the microfluidic chip is in contact with the heating plate, the microfluidic chip can be heated. The bakelite cover 35 is made of a heat insulating material to prevent the heat generated by the heating film from being transferred toward one side of the bakelite cover.

[0041] Preferably, the heat cover assembly 1a also includes a cylindrical heat-insulating cotton tube 36, and the sleeve 32 can be nested in the heat-insulating cotton tube 36. The heat-insulating cotton tube 36 can be made of a heat-insulating cotton tube. After the sleeve 32 is placed in the heat-insulating cotton tube 36 as a whole, the heat-insulating effect of the sleeve 32 can be improved to prevent the heat from being lost too quickly. The air nozzle seat 31a is arranged on the heat-insulating cotton tube 36, and the air nozzle suction cup 31b is arranged on the heating plate 33. The air nozzle seat 31a can rotate. After the air nozzle seat 31a and the air nozzle suction cup 31b are in contact with each other, the threaded connection between the air nozzle seat 31a and the air nozzle suction cup 31b can be achieved by rotating the air nozzle seat 31a.

[0042] Preferably, at least one heat cover guide post 41 is provided on the heating plate 33. A positioning hole may be provided on the microfluidic chip, and when in use, the heat cover guide post 41 can be inserted into the positioning hole, thereby improving the alignment effect between the heating plate and the microfluidic chip.

[0043] Preferably, both the first sensor and the second sensor can be angle sensors. The first drive assembly 45 can be a drive motor, which is arranged on the fixed bracket 7, and its shaft 47 can be connected to the bakelite cover 35. The second sensor can be coupled to the shaft, and then the angle of rotation of the hot cover assembly can be obtained. The second drive assembly can be a centrifugal motor 2a-2, and the first sensor can be coupled to the shaft of the centrifugal motor, and then the rotation angle of the centrifugal module assembly 2a can be obtained.

[0044] The present application also provides an automatic alignment method based on artificial intelligence, comprising the following steps: configuring a first sensor coupled to an upper module assembly to obtain first real-time position data of a first preset point in the upper module assembly; configuring a second sensor coupled to a lower module assembly to obtain second real-time position data of a second preset point in the lower module assembly; configuring a processor to obtain the relative angle between the first preset point and the second preset point based on the first real-time position data and the second real-time position data, and generating a control command for adjusting the state of the upper module assembly and / or the lower module assembly.

[0045] Preferably, the automatic alignment method based on artificial intelligence also includes the following steps: configuring a first drive component coupled to the upper module component to adjust the state of the upper module component; configuring a second drive component coupled to the lower module component to adjust the state of the lower module component; the first drive component and / or the second drive component operates based on the control command so that the relative angle is adjusted to a state less than a set threshold.

[0046] Finally, it should be noted that the above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art can still modify the technical solutions described in the aforementioned embodiments or replace some of the technical features therein by equivalents. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included in the protection scope of the present invention.

Claims

1. An automatic alignment device based on artificial intelligence, characterized in that: include: A first sensor (42) coupled to the upper module component (1), used to obtain first real-time position data of a first preset point in the upper module component (1); A second sensor (43) coupled to the lower module assembly (2), used to obtain second real-time position data of a second preset point in the lower module assembly (2); A processor (44) is used to obtain the relative angle between the first preset point and the second preset point based on the first real-time position data and the second real-time position data, and is capable of generating a control command for adjusting the state of the upper module component (1) and / or the lower module component (2); It also includes a first driving component (45) coupled to the upper module component (1) and used to adjust the state of the upper module component (1); It also includes a second driving component (46) coupled to the lower module component (2) and used to adjust the state of the lower module component (2); The first drive component (45) and / or the second drive component (46) can operate based on the control command so that the relative angle is adjusted to a state smaller than a set threshold; The lower module assembly (2) comprises a centrifugal module assembly (2a) and a first slide rail assembly (2b); the centrifugal module assembly (2a) comprises a centrifugal motor mounting plate (2a-1), a centrifugal motor (2a-2) and a turntable assembly (2a-3); the centrifugal motor (2a-2) is arranged on the centrifugal motor mounting plate (2a-1); the turntable assembly (2a-3) is connected to the centrifugal motor (2a-2); wherein the centrifugal motor (2a-2) can drive the turntable assembly (2a-3) to rotate based on the control command to change the state of the lower module assembly (2); The upper module assembly (1) comprises a heat cover assembly (1a) and a second slide rail assembly (1b); the heat cover assembly (1a) comprises a sleeve (32) and a heating disk (33) nested in the sleeve (32); a heat cover guide column (41) is arranged on the heating disk (33); wherein when the heat cover assembly (1a) moves toward the centrifugal module assembly (2a), the heat cover guide column (41) can abut against and contact the turntable assembly (2a-3); The turntable assembly (2a-3) comprises a turntable (13) and a high temperature resistant magnet (15) disposed on the turntable (13); the turntable (13) is detachably connected to a plastic chip assembly (2a-4); and the plastic chip assembly (2a-4) is provided with an iron sheet (27) capable of being adsorbed by the high temperature resistant magnet (15); The plastic chip assembly (2a-4) comprises a plastic chip (26) and a plurality of positioning holes (25) arranged on the plastic chip (26); the turntable (13) is provided with a plurality of positioning posts (24), the positioning posts (24) being capable of being nested in the positioning holes (25); wherein, when the heat cover assembly (1a) moves toward the centrifugal module assembly (2a), the heat cover guide posts (41) are capable of being nested in the positioning holes (25); The heat cover assembly (1a) further comprises a heating film (34), a bakelite cover (35) and a heat-insulating cotton cylinder (36); the bakelite cover (35) is nested in the sleeve (32); the heating film (34) is arranged in the sleeve (32) in a manner of being located between the bakelite cover (35) and the heating plate (33); and the sleeve (32) can be nested in the heat-insulating cotton cylinder (36); The heat cover assembly (1a) is provided with a first channel assembly (30) and a second channel assembly (31); the first channel assembly (30) and the second channel assembly (31) both comprise an air nozzle seat (31a) and an air nozzle suction cup (31b); the air nozzle seat (31a) is provided on the heat-insulating cotton cylinder (36), and the air nozzle suction cup (31b) is provided on the heat-generating plate (33).

Citation Information

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