Stainless steel chromatography column unit structure
By designing the stainless steel chromatography column unit structure, using a splicing structure of the separation discharge mechanism and the lifting chromatography unit, and combining with the cleaning system, the problems of difficulty in controlling liquid solvents, impurity accumulation and filtration systems in the prior art are solved, and the precise control and synchronous separation and purification of liquid solvents are achieved, and the automatic control and cleaning efficiency of the device are improved.
Patent Information
- Application Number
- CN202211096189.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2022-09-08
- Publication Date
- 2025-06-10
- Estimated Expiration
- 2042-09-08
AI Technical Summary
During the separation and purification process of existing chromatography column units, liquid solvents are difficult to control, resulting in uneven separation, impurities are easy to accumulate, and the filtration system is difficult to clean and maintain, which increases the limitations of the device.
A stainless steel chromatography column unit structure is designed, using a splicing structure of the separation discharge mechanism and the lifting chromatography unit, combining the cleaning system and the filter discharge component to realize the synchronous separation and purification of liquid solvents and automatic cleaning.
Through this structure, the precise control and synchronous separation and purification of liquid solvents are achieved, the automatic control and cleaning efficiency of the device is improved, maintenance and replacement work is simplified, and the flexibility of the device is enhanced.
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Figure CN115671794B_ABST
Abstract
Description
Technical Field
[0001] The present invention relates to the technical field of chromatography column unit equipment, specifically to the structure of a stainless-steel chromatography column unit. Background Technique
[0002] Chromatography is a method of separating and purifying chemical substances by taking advantage of the differences in the distribution coefficients of each component in a system in certain solvents and the differences in the adsorption capacities on adsorbents. This method is widely used in the chemical and pharmaceutical fields. Column chromatography is the most commonly used separation and purification method in chromatography technology. In addition to the properties of the adsorbent, solvent, and solute in the system and the comprehensive interaction among the three, the structure of the chromatography column itself is also one of the influencing factors.
[0003] When the current chromatography column unit performs separation and purification, it often needs to introduce a liquid solvent into a single group or multiple groups of chromatography columns for separation work. However, it is difficult to control the liquid solvent according to the volume, which increases the uneven separation of a single group of chromatography columns. At the same time, the impurities generated during separation are likely to accumulate in the chromatography column for a long time. It is difficult for the operator to manually remove the chromatography column for separation and purification. At the same time, the filtration system of the chromatography column is generally placed inside the column body, making it difficult to replace and clean, which increases the limitations of the device's use. Summary of the Invention
[0004] The purpose of the present invention is to provide the structure of a stainless-steel chromatography column unit to solve the related problems raised in the above background technique.
[0005] To achieve the above purpose, the present invention provides the following technical solution: The structure of a stainless-steel chromatography column unit includes a mounting frame. A separation and discharging mechanism is provided at the top of the mounting frame, and the separation and discharging mechanism respectively includes a mounting groove, a discharging cylinder, a control valve, a guide rod, a hemispherical separation chamber, a filter screen plate, a driver, a servo motor, a lead screw, and an internally threaded tube. A servo motor and a guide rod are respectively installed at one end of the top of the mounting frame. A lead screw is provided at the output end of the servo motor. An internally threaded tube with a threaded fit is provided on the outer side of the lead screw. A sleeve is provided on the outer side of the guide rod. A mounting groove is installed on the outer sides of the internally threaded tube and the sleeve. Three hemispherical separation chambers are provided inside the mounting groove. Three drivers are provided at one end of the back of the mounting groove. The output ends of the three drivers extend into the interior of the hemispherical separation chamber and are provided with a filter screen plate. The bottoms of the three hemispherical separation chambers are communicated with a discharging cylinder. Control valves are provided on the outer sides of the three discharging cylinders;
[0006] On both sides of the top of the mounting frame, there are lifting chromatography units, and each lifting chromatography unit respectively includes guide columns, guide sleeves, chromatography tanks, top plates, diversion pipes, material inlets, material pipes, solenoid valves and conical material inlets. On the top of the mounting frame, there are four groups of guide columns. Slidingly matched guide sleeves are arranged on the outer sides of the four groups of guide columns. Three chromatography tanks are installed between the four groups of guide sleeves. A bracket is arranged on the top of the three chromatography tanks, and a material pipe is arranged on the top of the bracket. Three diversion pipes are communicated with the bottom of the material pipe, and the three diversion pipes are communicated with the chromatography tanks. A material inlet is communicated with the middle position at the top of the material pipe. Solenoid valves are arranged at the communicating positions on both sides of the material pipe. Conical material inlets are installed at the bottoms inside the three chromatography tanks. At the middle position at one end of the top of the mounting frame, there is a lifting cylinder. The output end of the lifting cylinder is provided with a top plate, and the top plate is fixedly connected with one chromatography tank. Mounting plates are installed at one ends of the backs of both sides of the mounting frame.
[0007] Preferably, a cleaning system is arranged on the top of the mounting plate, and the cleaning system respectively includes a water tank, a water pump, a telescopic conduit and a water valve. The water tank is installed on the top of the mounting plate. A water pump is communicated with one end of the back of the water tank. The output end of the water pump is provided with a telescopic conduit. A water valve is communicated with the middle position at one end of the back of the material pipe. The telescopic conduit is communicated with the water valve.
[0008] Preferably, a filtering and draining component is arranged at the bottom of the mounting frame, and the filtering and draining component respectively includes a liquid receiving tank, a filter plate, a draining pump and a guard plate. The liquid receiving tank is installed at one end of the back at the bottom of the mounting frame. Filter plates are arranged at the tops of both sides inside the liquid receiving tank. Three draining pumps are arranged at the top of the liquid receiving tank, and the draining pumps are fitted and matched with the guard plate. A guard plate is communicated with the bottom at one end of the back of the liquid receiving tank.
[0009] Preferably, three through grooves are formed inside the mounting frame, and the three through grooves are in limit sliding fit with the mounting grooves. A limiting plate is installed inside the mounting frame, and a guide groove is formed at the top of the limiting plate. Guide wheels which are in sliding fit with the guide groove are arranged on both sides of the three discharging cylinders.
[0010] Preferably, the three hemispherical separation cavities are structurally adapted to the filter net plates. Brush plates which are in contact with the inner walls of the hemispherical separation cavities are arranged on both sides of the three filter net plates. Notches are formed at the tops and bottoms of the three filter net plates, and the notches are in clamping fit with the conical material inlets.
[0011] Preferably, three positioning grooves are arranged at the top of the mounting groove. Positioning clamping plates are arranged on both sides of the bottoms of the three chromatography tanks, and the positioning clamping plates are in sealing fit with the positioning grooves.
[0012] Preferably, the two solenoid valves control and cooperate with the communicating positions of the material pipe. The three diversion pipes are respectively communicated with the two sides and the middle position at the bottom of the material pipe.
[0013] Preferably, the three groups of conical feed openings are opposite to the vertical plane of the filter screen plate. A positioning frame is provided at the bottom of the three groups of conical feed openings, and the positioning frame extends to the inside of the hemispherical separation chamber and is in positioning cooperation with the filter screen plate.
[0014] Preferably, a water injection port is provided on one side of the top of the water tank, and the telescopic conduit is composed of a liquid guide pipe and a telescopic hose.
[0015] Preferably, rubber pads are provided inside the three groups of guard plates, and the three groups of guard plates are in a semi-circular arc structure and are in limit fit with the outer side of the discharge cylinder.
[0016] Compared with the prior art, the present invention provides a stainless steel chromatography column unit structure, which has the following beneficial effects:
[0017] 1. Through the splicing structure cooperation of the separation and discharge mechanism and the lifting chromatography unit, the present invention can form three groups of chromatography separation systems for the separation chromatography operation of liquid solvents. By using the connection and cooperation of the guide pipe with the three groups of diversion pipes and the chromatography tank, it is convenient to carry out single-group or multi-group synchronous separation and purification work according to the volume of the liquid solvent under the control of two solenoid valves. By using the connection and cooperation of the cleaning system and the guide pipe, cleaning water can be actively injected into the guide pipe, and the cleaning water can flow in the pipeline of the liquid solvent, so as to automatically clean the chromatography structure in the guide pipe, the chromatography tank and the hemispherical separation chamber, increasing the automatic control and cleaning efficiency of the device.
[0018] 2. By using the structural connection and positioning of the filter screen plate and the conical feed opening, the present invention can carry out the separation and purification work of the liquid solvent here, and accumulate the separated impurities in the filter screen plate. By starting the lifting of the lifting cylinder, the entire lifting chromatography unit can be actively lifted, so that the three groups of chromatography tanks are separated from the hemispherical separation chamber in the installation groove. At this time, the chromatography tank, the hemispherical separation chamber and the filter screen plate can be cleaned by injecting water from the cleaning system, and the filter screen plate can be driven to rotate centrifugally by the driver, not only scraping and cleaning the inside of the hemispherical separation chamber, but also efficiently flushing and removing the impurities separated on the surface of the filter screen plate, greatly improving the cleaning effect of the structure.
[0019] 3. By separating the three groups of chromatography tanks from the hemispherical separation chamber in the installation groove, the separation structure of the hemispherical separation chamber can be exposed. Under the horizontal displacement of the installation groove, the structure can be moved to the other end face for maintenance, repair and replacement work. The cleaning waste liquid accumulated in the hemispherical separation chamber can be discharged into the liquid receiving tank for filtration, so as to separate the impurities and the waste liquid, so as to directly discharge the waste liquid, increasing the convenience of impurity treatment. BRIEF DESCRIPTION OF THE DRAWINGS
[0020] Figure 1 is the front view of the present invention;
[0021] Figure 2 is the front sectional view of the present invention;
[0022] Figure 3 is the developed front view of the present invention;
[0023] Figure 4 is the rear sectional view of the present invention;
[0024] Figure 5 is the rear view of the present invention;
[0025] Figure 6 is the present invention Figure 2 magnified view at position A;
[0026] Figure 7 is the top sectional view of the mounting bracket of the present invention;
[0027] Figure 8 is the bottom view of the mounting groove of the present invention.
[0028] In the figure: 1, mounting bracket; 2, filtering and liquid discharging assembly; 21, liquid receiving tank; 22, filter plate; 23, liquid discharging pump; 24, guard plate; 3, separating and discharging mechanism; 31, mounting groove; 32, discharging cylinder; 33, control valve; 34, guide rod; 35, hemispherical separation cavity; 36, filter mesh plate; 37, driver; 38, servo motor; 39, lead screw; 310, internally threaded tube; 4, lifting cylinder; 5, lifting chromatography unit; 51, guide post; 52, guide sleeve; 53, chromatography tank; 54, top plate; 55, diversion tube; 56, feeding port; 57, feeding pipe; 58, solenoid valve; 59, conical feeding port; 6, mounting plate; 7, cleaning system; 71, water tank; 72, water pump; 73, telescopic conduit; 74, water valve. Detailed implementation manners
[0029] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.
[0030] Please refer to Figures 1-8, the present invention provides a technical solution: a stainless steel chromatography column unit structure, including a mounting frame 1. At the top of the mounting frame 1, there is a separation and discharging mechanism 3. The separation and discharging mechanism 3 respectively includes a mounting groove 31, a discharging cylinder 32, a control valve 33, a guide rod 34, a hemispherical separation cavity 35, a filter screen plate 36, a driver 37, a servo motor 38, a lead screw 39 and an internally threaded tube 310. At one end of the top of the mounting frame 1, a servo motor 38 and a guide rod 34 are respectively installed. The output end of the servo motor 38 is provided with a lead screw 39. The outside of the lead screw 39 is provided with an internally threaded tube 310 with a threaded fit. The outside of the guide rod 34 is provided with a sleeve. The outside of the internally threaded tube 310 and the sleeve is installed with a mounting groove 31. Inside the mounting groove 31, there are three groups of hemispherical separation cavities 35. At one end of the back of the mounting groove 31, there are three groups of drivers 37. The output ends of the three groups of drivers 37 extend into the inside of the hemispherical separation cavity 35 and are provided with a filter screen plate 36. The bottoms of the three groups of hemispherical separation cavities 35 are communicated with a discharging cylinder 32. The outside of the three groups of discharging cylinders 32 is provided with a control valve 33;
[0031] On both sides of the top of the mounting frame 1, there is a lifting chromatography unit 5. The lifting chromatography unit 5 respectively includes a guide post 51, a guide sleeve 52, a chromatography tank 53, a top plate 54, a diversion pipe 55, a feeding port 56, a feeding pipe 57, an electromagnetic valve 58 and a conical feeding port 59. At the top of the mounting frame 1, there are four groups of guide posts 51. The outside of the four groups of guide posts 51 is provided with slidingly matched guide sleeves 52. Between the four groups of guide sleeves 52, three groups of chromatography tanks 53 are installed. At the top of the three groups of chromatography tanks 53, there is a bracket. And at the top of the bracket, there is a feeding pipe 57. The bottom of the feeding pipe 57 is communicated with three groups of diversion pipes 55. And the three groups of diversion pipes 55 are communicated with the chromatography tank 53. At the middle position of the top of the feeding pipe 57, there is a feeding port 56. At the communicating positions on both sides of the feeding pipe 57, there is an electromagnetic valve 58. At the bottom inside the three groups of chromatography tanks 53, there is a conical feeding port 59. At the middle position of one end of the top of the mounting frame 1, there is a lifting cylinder 4. The output end of the lifting cylinder 4 is provided with a top plate, and the top plate is fixedly connected with one group of chromatography tanks 53. At one end of the back of both sides of the mounting frame 1, there is a mounting plate 6.
[0032] As a preferred solution of this embodiment: At the top of the mounting plate 6, there is a cleaning system 7. The cleaning system 7 respectively includes a water tank 71, a water pump 72, a telescopic conduit 73 and a water valve 74. The water tank 71 is installed at the top of the mounting plate 6. At one end of the back of the water tank 71, there is a communicated water pump 72. The output end of the water pump 72 is provided with a telescopic conduit 73. At the middle position of one end of the back of the feeding pipe 57, there is a communicated water valve 74. The telescopic conduit 73 is communicated with the water valve 74, which is convenient for introducing the cleaning liquid into the liquid guiding pipeline and prompting the liquid to be introduced into the device for cleaning work.
[0033] As a preferred solution of this embodiment: A filter drainage assembly 2 is provided at the bottom of the mounting frame 1. The filter drainage assembly 2 includes a liquid receiving tank 21, a filter plate 22, a drainage pump 23, and a guard plate 24 respectively. The liquid receiving tank 21 is installed at one end of the back surface of the bottom of the mounting frame 1. Filter plates 22 are provided at the tops of both sides inside the liquid receiving tank 21. Three drainage pumps 23 are provided at the top of the liquid receiving tank 21, and the drainage pumps 23 are fitted and matched with the guard plate 24. The bottom of one end of the back surface of the liquid receiving tank 21 communicates with the guard plate 24. The mutual cooperation of the filter structures can be used to receive the introduced water liquid and impurities, and separate the water liquid and impurities, increasing the convenience of subsequent cleaning work.
[0034] As a preferred solution of this embodiment: Three through grooves are opened inside the mounting frame 1, and the three through grooves are in limit sliding fit with the mounting groove 31. A limit plate is installed inside the mounting frame 1, and a guide groove is opened at the top of the limit plate. Guide wheels that are in sliding fit with the guide groove are provided on both sides of the three discharging cylinders 32, increasing the guiding property and stability of the overall displacement of the mounting groove 31.
[0035] As a preferred solution of this embodiment: The three hemispherical separation cavities 35 are structurally adapted to the filter net plates 36. Brush plates that are in contact with the inner walls of the hemispherical separation cavities 35 are provided on both sides of the three filter net plates 36. Notches are provided at the tops and bottoms of the three filter net plates 36, and the notches are in snap fit with the conical guide openings 59. The inner walls can be wiped and cleaned by contacting the brush plates with the inner walls of the three hemispherical separation cavities 35 when the filter net plates 36 rotate.
[0036] As a preferred solution of this embodiment: Three positioning grooves are provided at the top of the mounting groove 31. Positioning clamping plates are provided on both sides of the bottoms of the three chromatography tanks 53, and the positioning clamping plates are in sealing fit with the positioning grooves. The sealing fit of the positioning clamping plates and the positioning grooves greatly improves the sealing performance of the connection between the mounting groove 31 and the chromatography tank 53.
[0037] As a preferred solution of this embodiment: Two solenoid valves 58 control and cooperate with the connection of the guide pipe 57. The three diversion pipes 55 are respectively communicated with both sides and the middle position at the bottom of the guide pipe 57. Liquid solvents or cleaning water liquid can be introduced into the chromatography device from three directions, so as to perform chromatography separation or cleaning work on the chromatography device.
[0038] As a preferred solution of this embodiment: The three conical guide openings 59 are opposite to the vertical planes of the filter net plates 36. A positioning frame is provided at the bottom of the three conical guide openings 59, and the positioning frame extends to the inside of the hemispherical separation cavity 35 and is in positioning fit with the filter net plates 36, facilitating the separation and purification of the solvent through the guiding cooperation of the filter net plates 36 and the inner conical guide openings 59.
[0039] As a preferred solution of this embodiment: a water injection port is provided on one side of the top of the water tank 71, and the telescopic conduit 73 is respectively composed of a liquid guide pipe and a telescopic hose, which is convenient to adapt to the lifting adjustment of the device by using the telescopic structure of the telescopic conduit 73.
[0040] As a preferred solution of this embodiment: rubber pads are provided on the inner sides of the three groups of guard plates 24, and the three groups of guard plates 24 are in a semi-circular structure and are in limiting fit with the outer side of the discharge cylinder 32, increasing the positioning effect of the guard plates 24 on the discharge cylinder 32.
[0041] Example 1, as Figures 1-5 shown, when the device is being cleaned, the lifting cylinder 4 can be started to drive a chromatographic tank 53 to rise, so that the rising chromatographic tank 53 drives the guide sleeve 52 and the other two chromatographic tanks 53 to rise under the guiding cooperation of the guide posts 51, thereby automatically releasing the sealing structure between the chromatographic tank 53 and the hemispherical separation cavity 35, and releasing the contact positioning between the conical feed port 59 and the filter screen plate 36. At this time, when cleaning work is carried out, the filter screen plate 36 can be driven to rotate by starting the driver 37. At this time, not only are impurities quickly discharged by the rotation of the filter screen plate 36, and with the flushing of the water liquid, the cleaning quality of the filter screen plate 36 is greatly improved. At the same time, as the filter screen plate 36 rotates and frictionally contacts the hemispherical separation cavity 35, the inner wall of the hemispherical separation cavity 35 is scraped, further improving the cleaning effect of the impurities and the device.
[0042] Example 2, as Figures 3-7 shown, when cleaning work is carried out in the chromatographic tank 53 and the hemispherical separation cavity 35, the flow passage of the discharge cylinder 32 can be closed by the control valve 33. After the internal structure is cleaned, then the servo motor 38 is started to drive the lead screw 39 to rotate, so that the internally threaded pipe 310 moves horizontally as the lead screw 39 rotates, and then drives the entire mounting groove 31 to move horizontally under the limiting cooperation of the sleeve and the guide rod 34, so that the mounting groove 31 drives the three groups of discharge cylinders 32 and the hemispherical separation cavity 35 to move to the other end, and makes the discharge cylinder 32 contact the guard plate 24. At this time, the control valve 33 can be opened, and the waste liquid is discharged into the liquid receiving tank 21, so that the water liquid and the impurities are separated on the filter plate 22, and finally the waste liquid is discharged through the guard plate 24, so as to dispose of the collected impurities together, greatly increasing the convenience and flexibility of the automatic cleaning of the device.
[0043] Working principle: When the device is in use, the liquid solvent can be introduced into the guide pipe 57 from the material guide port 56. During this process, through the control of two groups of solenoid valves 58, according to the volume of the liquid solvent, the liquid can enter the chromatography tank 53 from one group, two groups or three groups of diversion pipes 55, so as to carry out single-group, double-group or three-group synchronous chromatography separation operations. Through the conical material guide port 59 in the chromatography tank 53, the liquid solvent can be guided to the filter mesh plate 36 for separation, and finally fall into the discharge cylinder 32 from the hemispherical separation cavity 35. During this period, the on-off flow rate of solvent filtration can be changed by starting the control valve 33, and finally the solvent after chromatography separation from the discharge cylinder 32 can be discharged and collected.
[0044] When cleaning the device, the guiding of the liquid solvent by the material guide port 56 can be cancelled. Then, the water in the water tank 71 is pumped out by starting the water pump 72, and the water valve 74 is opened to make the water liquid enter the water valve 74 from the telescopic conduit 73. During this period, according to the control of the two groups of solenoid valves 58, the cleaning liquid can enter one group, two groups or three groups of chromatography tanks 53 respectively to clean the chromatography columns, and the cleaning water liquid can enter the hemispherical separation cavity 35 through the chromatography tank 53 to flush the filter structure of the filter mesh plate 36. After cleaning, the water liquid and impurities are discharged from the discharge cylinder 32 to achieve the self-cleaning effect of the chromatography system of the device.
[0045] Finally, it should be noted that the above content is only used to illustrate the technical solution of the present invention, rather than limiting the protection scope of the present invention. Any simple modification or equivalent replacement of the technical solution of the present invention by those of ordinary skill in the art does not depart from the essence and scope of the technical solution of the present invention.
Claims
1. The structure of the stainless - steel chromatography column unit includes a mounting frame (1). It is characterized in that: A separation and discharging mechanism (3) is provided at the top of the mounting frame (1). The separation and discharging mechanism (3) respectively includes a mounting groove (31), a discharging cylinder (32), a control valve (33), a guide rod (34), a hemispherical separation chamber (35), a filter screen plate (36), a driver (37), a servo motor (38), a lead screw (39) and an internally threaded tube (310). At one end of the top of the mounting frame (1), a servo motor (38) and a guide rod (34) are respectively installed. The output end of the servo motor (38) is provided with a lead screw (39). An internally threaded tube (310) with a threaded fit is arranged on the outer side of the lead screw (39). A sleeve is arranged on the outer side of the guide rod (34). The mounting groove (31) is installed on the outer sides of the internally threaded tube (310) and the sleeve. Three hemispherical separation chambers (35) are arranged inside the mounting groove (31). At one end of the back of the mounting groove (31), three drivers (37) are provided. The output ends of the three drivers (37) extend into the hemispherical separation chambers (35) and are provided with filter screen plates (36). The bottoms of the three hemispherical separation chambers (35) are communicated with a discharging cylinder (32). Control valves (33) are arranged on the outer sides of the three discharging cylinders (32). Lifting chromatography units (5) are provided on both sides of the top of the mounting frame (1). The lifting chromatography units (5) respectively include guide columns (51), guide sleeves (52), chromatography tanks (53), top plates (54), diversion pipes (55), feeding ports (56), feeding pipes (57), solenoid valves (58) and conical feeding ports (59). Four guide columns (51) are provided at the top of the mounting frame (1). Guide sleeves (52) with a sliding fit are arranged on the outer sides of the four guide columns (51). Three chromatography tanks (53) are installed between the four guide sleeves (52). A support is provided at the top of the three chromatography tanks (53), and a feeding pipe (57) is provided at the top of the support. Three diversion pipes (55) are communicated with the bottom of the feeding pipe (57), and the three diversion pipes (55) are communicated with the chromatography tanks (53). A feeding port (56) is communicated with the middle position at the top of the feeding pipe (57). Solenoid valves (58) are arranged at the communicating positions on both sides of the feeding pipe (57). Conical feeding ports (59) are installed at the bottoms inside the three chromatography tanks (53). A lifting cylinder (4) is provided at the middle position at one end of the top of the mounting frame (1). The output end of the lifting cylinder (4) is provided with a top plate, and the top plate is fixedly connected to one chromatography tank (53). Mounting plates (6) are installed at one end of the back of both sides of the mounting frame (1).
2. The structure of the stainless - steel chromatography column unit according to claim 1, It is characterized in that: The top of the mounting plate (6) is provided with a cleaning system (7), and the cleaning system (7) respectively includes a water tank (71), a water pump (72), a telescopic conduit (73) and a water valve (74). The water tank (71) is installed on the top of the mounting plate (6). One end of the back surface of the water tank (71) is communicated with the water pump (72). The output end of the water pump (72) is provided with the telescopic conduit (73). The middle position of one end of the back surface of the material guide pipe (57) is communicated with the water valve (74). The telescopic conduit (73) is communicated with the water valve (74).
3. The stainless steel chromatography column unit structure according to claim 1, characterized in that: A filter and drainage assembly (2) is provided at the bottom of the mounting frame (1), and the filter and drainage assembly (2) respectively includes a liquid receiving tank (21), a filter plate (22), a drainage pump (23) and a guard plate (24). The liquid receiving tank (21) is installed at one end of the back surface of the bottom of the mounting frame (1). Filter plates (22) are provided at the tops of both sides inside the liquid receiving tank (21). Three drainage pumps (23) are provided at the top of the liquid receiving tank (21), and the drainage pumps (23) are fitted and matched with the guard plate (24). The bottom of one end of the back surface of the liquid receiving tank (21) is communicated with the guard plate (24).
4. The stainless steel chromatography column unit structure according to claim 1, characterized in that: Three through grooves are opened inside the mounting frame (1), and the three through grooves are in limit sliding fit with the mounting groove (31). A limiting plate is installed inside the mounting frame (1), and a guide groove is opened at the top of the limiting plate. Guide wheels in sliding fit with the guide groove are provided on both sides of the three discharging cylinders (32).
5. The stainless steel chromatography column unit structure according to claim 1, characterized in that: The three hemispherical separation cavities (35) are structurally adapted to the filter mesh plates (36). Brush plates in contact with the inner walls of the hemispherical separation cavities (35) are provided on both sides of the three filter mesh plates (36). Notches are provided at the tops and bottoms of the three filter mesh plates (36), and the notches are in snap fit with the conical material guide openings (59).
6. The stainless steel chromatography column unit structure according to claim 1, characterized in that: Three positioning grooves are provided at the top of the mounting groove (31). Positioning clamping plates are provided on both sides of the bottoms of the three chromatography tanks (53), and the positioning clamping plates are in sealing fit with the positioning grooves.
7. The stainless steel chromatography column unit structure according to claim 1, characterized in that: The two electromagnetic valves (58) control and cooperate with the connection part of the material guide pipe (57). The three diversion pipes (55) are respectively communicated with both sides and the middle position of the bottom of the material guide pipe (57).
8. The stainless steel chromatography column unit structure according to claim 1, characterized in that: The three conical material guide openings (59) are opposite to the vertical planes of the filter mesh plates (36). A positioning frame is provided at the bottom of the three conical material guide openings (59), and the positioning frame extends to the inside of the hemispherical separation cavity (35) and is in positioning cooperation with the filter mesh plate (36).
9. The stainless steel chromatography column unit structure according to claim 2, characterized in that: One side of the top of the water tank (71) is provided with a water injection port, and the telescopic conduit (73) is respectively composed of a liquid guide pipe and a telescopic hose.
10. The stainless steel chromatography column unit structure according to claim 3, characterized in that: Rubber pads are arranged on the inner sides of the three groups of guard plates (24), and the three groups of guard plates (24) are in a semi-circular structure and are in limiting fit with the outer side of the discharge cylinder (32).
Citation Information
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A fully-automatic chromatographic column
CN104307207A
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