Automatic Analysis System for Mixing Devices and Their Applications
By combining the frame, guide, reaction vessel housing, clutch assembly, and drive assembly, the problem of unstable resetting of the mixing device is solved, and the stable resetting and mixing action of the reaction vessel housing are realized, thus improving the mixing effect.
Patent Information
- Application Number
- CN202211502916.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2022-11-28
- Publication Date
- 2025-11-14
- Estimated Expiration
- 2042-11-28
AI Technical Summary
In the prior art, the resetting of the mixing device is unstable, which causes the mixing device to be unable to move accurately to the initial position, affecting the mixing effect.
The system employs a combined structure of frame, guide, reaction vessel housing, clutch assembly, and drive assembly. Through the cooperation of eccentric mechanism and elastic element, it achieves stable reciprocating movement of the reaction vessel housing between the initial position and the maximum stroke position, ensuring accurate resetting.
This improves the reset stability of the reaction vessel in the mixing device, ensuring the effective mixing action and avoiding positional errors caused by drive motor stall or loss of synchronization.
Smart Images

Figure CN115722121B_ABST
Abstract
Description
Technical Field
[0001] This application relates to the field of medical device technology, and in particular to a mixing device and an automated analysis system for its application. Background Technology
[0002] With the development and application of in vitro diagnostic medical technology, in vitro diagnostics has become an important auxiliary means of disease diagnosis, and automated diagnostic equipment is increasingly favored by society. Regarding the need for mixing substances in reaction vessels within automated analysis systems, existing technologies offer various implementation methods, such as motor-driven and electromagnet-driven systems. However, the mixing action and the resetting of the entire mixing device after mixing stops all require direct connection to the drive motor. This reliance on the drive motor for mixing and resetting actions leads to a problem during resetting: the mixing device cannot move back to its initial position due to the motor's own rotational error. Therefore, there is an urgent need for a mixing device with more stable resetting capabilities. Summary of the Invention
[0003] The purpose of this application is to provide a more stable resetting mixing device and an automatic analysis system for its application.
[0004] In a first aspect, this application provides a mixing device, comprising: a frame on which a guide member is disposed; a reaction vessel housing slidably disposed on the guide member, having an initial position and a maximum stroke position, comprising a receiving cavity and an eccentric cavity disposed opposite thereto; a clutch assembly comprising a first elastic member forcing the reaction vessel housing to slide from the maximum stroke position toward the initial position, a passive member having an eccentric mechanism at one end and a driven mechanism at the other end, an active member having a main driving mechanism at one end and a connecting mechanism at the other end, and a second elastic member, the eccentric mechanism being housed in the eccentric cavity; and a drive assembly comprising a drive... The device comprises a drive member and a rotating member driven by the drive member, wherein the connecting mechanism is slidably disposed on the rotating member, and the second elastic member forces the drive member to move toward the driven member so that the drive mechanism abuts against the driven mechanism; wherein, during the rotation of the drive member along the rotating member in a first direction, the eccentric mechanism abuts against the eccentric cavity so that the reaction vessel housing reciprocates between an initial position and a maximum stroke position; during the rotation of the drive member along the rotating member in a second direction opposite to the first direction, the reaction vessel housing moves toward the initial position or remains in the initial position.
[0005] Furthermore, the driven mechanism is provided with a sliding surface and a blocking surface, and the main driving mechanism is provided with a main sliding surface and a main blocking surface. When the reaction vessel accommodating seat moves from the initial position to the maximum stroke position, the blocking surface abuts against the main blocking surface. The passive component also includes a connecting rotating component, one end of which is connected to the eccentric mechanism and the other end of which is connected to the driven mechanism.
[0006] Furthermore, the eccentric mechanism includes a rotating wheel that abuts against the eccentric cavity and an eccentric protrusion fixedly connected to the axis of the rotating wheel; the eccentric protrusion is disposed at one end of the connecting rotating member.
[0007] Furthermore, the frame also includes a base plate, a first side plate and a second side plate fixedly disposed on the base plate, and a top plate fixedly disposed on the first side plate and the second side plate; the base plate is provided with a drive component mounting hole, the top plate is provided with a clutch component mounting hole, and the connecting rotating member is rotatably disposed in the clutch component mounting hole.
[0008] Furthermore, there is a gap between the top plate and the bottom plate, and the driven mechanism, the main drive mechanism, the connecting mechanism, and the second elastic member are disposed within the gap; one end of the second elastic member abuts against the bottom plate, and the other end of the second elastic member abuts against the connecting mechanism.
[0009] Furthermore, the rotating member is rotatably disposed within the mounting hole of the drive assembly, and the second elastic member is sleeved outside the rotating member.
[0010] Furthermore, the frame also includes a third side plate and a fourth side plate, the third side plate and the fourth side plate being disposed opposite to each other, the third side plate and the fourth side plate being fixedly disposed on both sides of the top plate and not parallel to the first side plate or the second side plate; one end of the guide member is fixed to the third side plate, and the other end of the guide member is fixed to the fourth side plate; one end of the first elastic member abuts against the third side plate or the fourth side plate, and the other end of the first elastic member abuts against the reaction vessel housing.
[0011] Furthermore, the first elastic element is a compression spring, having a first compression state and a second compression state. When the first elastic element is in the second compression state, it is further compressed relative to when it is in the first compression state. The second elastic element is a compression spring, having a third compression state and a fourth compression state. When the second elastic element is in the fourth compression state, it is further compressed relative to when it is in the third state. When the reaction vessel housing is in the maximum stroke position, the first elastic element is in the second compression state. When the reaction vessel housing is in the initial position, the first elastic element is in the first compression state, and the second elastic element is in the third compression state.
[0012] Secondly, this application provides a mixing method applied to the above-mentioned mixing apparatus, comprising:
[0013] In the mixing step, the driving member drives the rotating member to rotate along the first direction, and the active member rotates with the rotating member;
[0014] In the reset step, the driving component drives the rotating component to rotate along the second direction;
[0015] During the rotation of the active component along the first direction with the rotating component, the eccentric mechanism abuts against the eccentric cavity to cause the reaction vessel accommodating seat to reciprocate between the initial position and the maximum stroke position; during the rotation of the active component along the second direction with the rotating component, the reaction vessel accommodating seat moves toward the initial position or remains at the initial position.
[0016] Thirdly, this application provides an automatic analysis system that includes the aforementioned mixing device.
[0017] Compared with existing technologies, the mixing device provided in this application has an initial position and a maximum stroke position. During the rotation of the active component along the first direction with the rotating component, the eccentric mechanism abuts against the eccentric cavity, causing the reaction vessel accommodating seat to reciprocate between the initial position and the maximum stroke position. During the rotation of the active component along the second direction opposite to the first direction with the rotating component, the reaction vessel accommodating seat moves towards the initial position or remains in the initial position. Compared with existing technologies that only use a drive motor to reset the reaction vessel accommodating seat, even if the drive motor stalls or loses synchronization, the reaction vessel accommodating seat can still return to the initial position under the action of the first elastic component. This configuration achieves both mixing of the material within the reaction vessel accommodating seat and resetting of the reaction vessel accommodating seat, improving the stability of the reaction vessel accommodating seat resetting in the mixing device. Attached Figure Description
[0018] To more clearly illustrate the technical solutions in the specific embodiments of this application or the prior art, the drawings used in the description of the specific embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are some embodiments of this application. For those skilled in the art, other drawings can be obtained from these drawings without creative effort.
[0019] Figure 1 This is a schematic diagram of the mixing device provided in the embodiments of this application;
[0020] Figure 2 This is a cross-sectional view of the mixing apparatus provided in the embodiments of this application;
[0021] Figure 3 This is an exploded view of the mixing apparatus provided in the embodiments of this application;
[0022] Figure 4 This is a side view of the mixing apparatus provided in the embodiments of this application when the reaction vessel housing is in the initial position;
[0023] Figure 5 This is a schematic diagram of the structure of the reaction vessel housing provided in the embodiments of this application;
[0024] Figure 6 This is a cross-sectional view of the reaction vessel housing provided in an embodiment of this application;
[0025] Figure 7 This is a schematic diagram of the framework provided in the embodiments of this application;
[0026] Figure 8 This is a schematic diagram of the framework provided in the embodiments of this application;
[0027] Figure 9 A cross-sectional view of the framework provided in the embodiments of this application;
[0028] Figure 10 A schematic diagram of the driven mechanism provided in the embodiment of the application;
[0029] Figure 11 A schematic diagram of the active component provided in the application embodiment;
[0030] Figure 12 A side view of the driven mechanism provided in the embodiment of the application;
[0031] Figure 13 A side view of the active component provided in the embodiment of the application;
[0032] Figure 14 A side view of the driven mechanism provided in the embodiment of the application;
[0033] Figure 15 A side view of the active component provided in the application embodiment.
[0034] Figure label:
[0035] Framework 1;
[0036] Guide component 11;
[0037] Base plate 12;
[0038] Drive component mounting hole 121;
[0039] First side plate 13;
[0040] Second side panel 14;
[0041] Third side panel 15;
[0042] First hole 151;
[0043] Second hole 152;
[0044] Fourth side panel 16;
[0045] Third hole 161;
[0046] Fourth hole 162;
[0047] Top plate 17;
[0048] Clutch assembly mounting hole 171;
[0049] Gap 18;
[0050] Reaction vessel housing 2;
[0051] Receiving cavity 21;
[0052] Eccentric cavity 22;
[0053] Through hole 23;
[0054] Clutch assembly 3;
[0055] First elastic element 31;
[0056] Passive component 32;
[0057] Eccentric mechanism 321;
[0058] Rotating wheel 3211
[0059] Eccentric protrusion 3212;
[0060] Driven mechanism 322;
[0061] Sliding surface 3221;
[0062] 3222 (the surface of the backing);
[0063] Connecting rotating part 323;
[0064] First bearing 324;
[0065] Active component 33;
[0066] Main drive mechanism 331;
[0067] Main sliding surface 3311;
[0068] Main panel 3312;
[0069] Connection structure 332;
[0070] Second elastic element 34;
[0071] Driver component 4;
[0072] Drive component 41;
[0073] Rotating component 42;
[0074] Second bearing 43;
[0075] Fixing plate 5. Detailed Implementation
[0076] To make the objectives, technical solutions, and advantages of the embodiments of this application clearer, the technical solutions of the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this application, and not all embodiments. The components of the embodiments of this application described and shown in the accompanying drawings can generally be arranged and designed in various different configurations.
[0077] Therefore, the following detailed description of the embodiments of this application provided in the accompanying drawings is not intended to limit the scope of the claimed application, but merely to illustrate selected embodiments of the application. All other embodiments obtained by those skilled in the art based on the embodiments of this application without inventive effort are within the scope of protection of this application.
[0078] It should be noted that similar labels and letters in the following figures indicate similar items. Therefore, once an item is defined in one figure, it does not need to be further defined and explained in subsequent figures.
[0079] In the description of this application, it should be noted that the terms "center," "upper," "lower," "left," "right," "vertical," "horizontal," "inner," and "outer," etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings, or the orientation or positional relationship commonly used when the product of this application is in use. They are only for the convenience of describing this application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation on this application. In addition, the terms "first," "second," and "third," etc., are only used to distinguish descriptions and should not be construed as indicating or implying relative importance.
[0080] Furthermore, terms such as "horizontal," "vertical," and "sag" do not imply that components must be absolutely horizontal or suspended, but rather that they can be slightly tilted. For example, "horizontal" simply means that its direction is more horizontal relative to "vertical," and does not mean that the structure must be completely horizontal, but can be slightly tilted.
[0081] In the description of this application, it should also be noted that, unless otherwise expressly specified and limited, the terms "set up," "install," "connect," and "link" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this application based on the specific circumstances.
[0082] The following detailed description of some embodiments of this application is provided in conjunction with the accompanying drawings. Unless otherwise specified, the following embodiments and features can be combined with each other.
[0083] like Figures 1 to 6 , Figures 10 to 15 As shown in the figure, this application provides a mixing apparatus, which includes:
[0084] Frame 1, on which a guide component 11 is provided.
[0085] The reaction vessel housing 2 is slidably mounted on the guide member 11 and has an initial position and a maximum stroke position. It includes a housing cavity 21 and an eccentric cavity 22 disposed opposite to it. In this embodiment, the housing cavity 21 can hold, but is not limited to, a reaction vessel, liquid, or a mixture thereof.
[0086] The clutch assembly 3 includes a first elastic member 31 that forces the reaction vessel housing 2 to slide from the maximum stroke position toward the initial position, a passive member 32 with an eccentric mechanism 321 at one end and a driven mechanism 322 at the other end, an active member 33 with a main drive mechanism 331 at one end and a connecting mechanism 332 at the other end, and a second elastic member 34. The eccentric mechanism 321 is housed in the eccentric cavity 22.
[0087] The drive assembly 4 includes a drive member 41 and a rotating member 42 driven to rotate by the drive member 41. The connecting mechanism 332 is slidably disposed on the rotating member 42. The second elastic member 34 forces the active member 33 to move toward the passive member 32 so that the main drive mechanism 331 abuts against the driven mechanism 322.
[0088] During the rotation of the active member 33 along the first direction with the rotating member 42, the eccentric mechanism 321 abuts against the eccentric cavity 22 to cause the reaction vessel accommodating seat 2 to reciprocate between the initial position and the maximum stroke position; during the rotation of the active member 33 along the second direction opposite to the first direction with the rotating member 42, the reaction vessel accommodating seat 2 moves toward the initial position or remains in the initial position.
[0089] like Figure 1As shown, in this embodiment, the first direction is a counterclockwise rotation direction, and the second direction is a clockwise rotation direction. By changing the structure of the main drive mechanism 331 and the driven mechanism 322, the first direction can also be changed to a clockwise direction, and the second direction can be changed to a counterclockwise direction.
[0090] like Figure 4 As shown, the reaction vessel accommodating seat 2 is in the initial position, at which time the first elastic element 31 is in the first compressed state. The reaction vessel accommodating seat 2 moves along the guide 11, further compressing the first elastic element 31 and compressing the first elastic element 31 to the second compressed state, at which point the position of the reaction vessel accommodating seat 2 is the maximum stroke position.
[0091] like Figures 1 to 4 As shown, in this embodiment, the driving component 41 is a gear. The driving component 41 can be replaced by other mechanisms that can provide power to the rotating component 42, including but not limited to a motor, crank, rotating wheel, etc.
[0092] Compared with the prior art, the reaction vessel accommodating seat 2 in the mixing device provided in this application has an initial position and a maximum stroke position. During the rotation of the driving member 33 along the first direction with the rotating member 42, the eccentric mechanism 321 abuts against the eccentric cavity 22, causing the reaction vessel accommodating seat 2 to reciprocate between the initial position and the maximum stroke position. During the rotation of the driving member 33 along the second direction opposite to the first direction with the rotating member 42, the reaction vessel accommodating seat 2 moves towards the initial position or remains in the initial position. Unlike the prior art where only the driving motor performs the reset action on the reaction vessel accommodating seat 2, even if the driving motor stalls or loses synchronization, the reaction vessel accommodating seat 2 can still return to the initial position under the action of the first elastic member 31. This configuration achieves both mixing of the material inside the reaction vessel accommodating seat 2 and reset of the reaction vessel accommodating seat 2, improving the stability of the reset of the reaction vessel accommodating seat 2 in the mixing device.
[0093] like Figure 1 , Figures 10 to 15 As shown, the driven mechanism 322 is provided with a sliding surface 3221 and a blocking surface 3222, and the main driving mechanism 331 is provided with a main sliding surface 3311 and a main blocking surface 3312. When the reaction vessel accommodating seat 2 moves from the initial position to the maximum stroke position, the blocking surface 3222 abuts against the main blocking surface 3312. The main blocking surface 3312 pushes the blocking surface 3222, causing the driving member 33 to push the driven mechanism 322 to move, and the driven mechanism 322 drives the reaction vessel accommodating seat 2 to move from the initial position to the maximum stroke position.
[0094] The passive component 32 also includes a connecting rotating component 323, one end of which is connected to the eccentric mechanism 321 and the other end of which is connected to the driven mechanism 322.
[0095] The eccentric mechanism 321 includes a rotating wheel 3211 that abuts against the eccentric cavity 22 and an eccentric protrusion 3212 that is fixedly connected to the axis of the rotating wheel 3211; the eccentric protrusion 3212 is disposed at one end of the connecting rotating member 323. In this embodiment, the eccentric protrusion 3212 can also be other eccentric structures that provide reciprocating motion power to the reaction vessel receiving cavity 22.
[0096] The frame 1 also includes a base plate 12, a first side plate 13 and a second side plate 14 fixedly disposed on the base plate 12, and a top plate 17 fixedly disposed on the first side plate 13 and the second side plate 14.
[0097] The base plate 12 is provided with a drive component mounting hole 121, the top plate 17 is provided with a clutch component mounting hole 171, and the connecting rotating member 323 is rotatably disposed in the clutch component mounting hole 171.
[0098] There is a gap 18 between the top plate 17 and the bottom plate 12. The driven mechanism 322, the main drive mechanism 331, the connecting mechanism 332 and the second elastic member 34 are disposed in the gap 18. One end of the second elastic member 34 abuts against the bottom plate 12 and the other end opposite to one end of the second elastic member 34 abuts against the connecting mechanism 332.
[0099] The rotating member 42 is rotatably disposed within the drive assembly mounting hole 121, and the second elastic member 34 is sleeved on the outside of the rotating member 42.
[0100] The frame 1 further includes a third side plate 15 and a fourth side plate, the third side plate 15 and the fourth side plate 16 being disposed opposite to each other. The third side plate 15 and the fourth side plate 16 are fixedly disposed on both sides of the top plate 17 and are not parallel to the first side plate 13 or the second side plate 14. In this embodiment, the third side plate 15 and the fourth side plate 16 are disposed parallel to each other and perpendicular to the first side plate 13 or the second side plate 14. One end of the guide member 11 is fixed to the third side plate 15, and the other end opposite to one end of the guide member 11 is fixed to the fourth side plate 16. Figure 1 , Figure 3 , Figure 7 As shown, a fixing plate 5 is also fixed above the top plate 17 to prevent the connecting rotating part 323 from moving in a third direction.
[0101] like Figures 5 to 8As shown, in this embodiment, the frame 1 is also an integrally formed structure, or it can be an assembled structure. The third side plate 15 is provided with a first hole 151 and a second hole 152, and the fourth side plate 16 is provided with a third hole 161 and a fourth hole 162. The guide member 11 consists of two guide rods. The bottom sides of the reaction vessel accommodating seat 2 are each provided with a through hole 23. The two guide rods are fixed on the third side plate 15 and the fourth side plate 16. The reaction vessel accommodating seat 2 is slidably mounted on the guide member 11 through the through holes 23.
[0102] One end of the first elastic member 31 abuts against the third side plate 15 or the fourth side plate 16, and the other end opposite to one end of the first elastic member 31 abuts against the reaction vessel housing 2.
[0103] The first elastic element 31 is a compression spring. The first elastic element 31 has a first compression state and a second compression state. When the first elastic element 31 is in the second compression state, it is further compressed relative to when it is in the first compression state.
[0104] The second elastic element 34 is a compression elastic element. The second elastic element 34 has a third compression state and a fourth compression state. When the second elastic element 34 is in the fourth compression state, it is further compressed relative to when the second elastic element is in the third state.
[0105] When the reaction vessel housing 2 is in the maximum stroke position, the first elastic element 31 is in the second compression state.
[0106] When the reaction vessel accommodating seat 2 is in the initial position, the first elastic element 31 is in the first compression state and the second elastic element 34 is in the third compression state.
[0107] like Figures 10 to 15As shown, in this embodiment, the driving member 33 has eight spaced-apart main sliding surfaces 3311 and eight main blocking surfaces 3312 interspersed between the main sliding surfaces 3311. The passive mechanism 322 has eight spaced-apart slidable surfaces 3221 and eight blocking surfaces 3222 interspersed between the slidable surfaces 3221. Eight passive teeth are provided on the contact surface between the driven mechanism 322 and the main driving mechanism 331, and eight driving teeth are provided on the contact surface between the driven mechanism 322 and the main driving mechanism 331. The main driving mechanism 331 has a driving plane gap between two driving teeth, and the angle α between its driving plane and the plane of the main sliding surface 3311 is 158°. The driven mechanism 322 has a passive plane gap between two passive teeth, and the angle β between its passive plane and the plane of the slidable surface 3221 is 158°. Experiments have verified that, while keeping the included angles α and β constant, having 8 passive teeth on the contact surface between the driven mechanism 322 and the main driving mechanism 331, and 8 active teeth on the contact surface between the driven mechanism 322 and the main driving mechanism 331, results in less wear on the active and passive teeth, and faster reset of the reaction vessel housing 2, compared to having 4 or 6 passive teeth on the contact surface between the driven mechanism 322 and the main driving mechanism 331. The number of active and passive teeth can be changed according to the elastic force of the first elastic element 31, the elastic force of the second elastic element 24, and the included angles α and β. Furthermore, other guide surfaces or structures that do not reduce the reset stability of the reaction vessel housing cavity can also be provided on the main driving mechanism 331 and the driven mechanism 322.
[0108] like Figure 1 , Figure 3 , Figure 4 As shown, the guide member 11 is a guide rod, and the reaction vessel receiving seat 2 includes two receiving cavities 21 located at the top of the reaction vessel receiving seat 2, two through holes 3052 located at the bottom of the reaction vessel receiving seat 2, and an eccentric cavity 22 located between the two receiving cavities 21; the rotating wheel 3211 is disposed in the eccentric cavity 22, the guide rod passes through the through hole 3052, and both ends of the guide rod are connected to the third side plate 15 and the fourth side plate 16, respectively; one end of the first elastic member 31 abuts against the reaction vessel receiving seat 2, and the other end opposite to one end of the first elastic member 31 abuts against the fourth side plate 16 or the third side plate 15. The guide member 11 can also be replaced by other structures that realize guiding and limiting functions, such as slide rails, sliders, and screws.
[0109] A mixing method is applied to the above-mentioned mixing apparatus, which has a mixing step and a resetting step.
[0110] In the mixing step, the driving member 41 drives the rotating member 42 to rotate along the first direction, and the active member 33 rotates with the rotating member 42;
[0111] In the reset step, the driving member 41 drives the rotating member 42 to rotate along the second direction;
[0112] During the rotation of the active member 33 along the first direction with the rotating member 42, the eccentric mechanism 321 abuts against the eccentric cavity 22 to cause the reaction vessel receiving seat 2 to reciprocate between the initial position and the maximum stroke position; during the rotation of the active member 33 along the second direction with the rotating member 42, the reaction vessel receiving seat 2 moves toward the initial position or remains at the initial position.
[0113] The specific process of the mixing step is as follows:
[0114] Step S1, as follows Figure 4 As shown, the reaction vessel accommodating seat 2 in the mixing device is in the initial position and abuts against the third side plate 15 (it can also be set to abut against the fourth side plate 16, but in this embodiment it is set to abut against the third side plate 15). At this time, the driving member 41 is stationary, the first elastic member 31 is in the first state, and the second elastic member 34 is in the third state.
[0115] In step S2, the driving member 41 moves in the first direction, driving the rotating member 42 to rotate in the first direction. The rotating member 42 drives the active member 33 to rotate in the first direction. Under the push of the second elastic member 34, the main drive mechanism 331 abuts against the driven mechanism 322. The main stop surface abuts against the stopped surface 3222 and pushes the stopped surface 3222 to move. The main drive mechanism 331 drives the driven mechanism 322 to rotate in the first direction. The driven mechanism 322 drives the connecting rotating member 323 to rotate in the first direction. The connecting rotating member 323 drives the eccentric protrusion 3212 to rotate in the first direction. The rotating wheel 3211 drives the reaction vessel receiving seat 2 to move along the guide member 11 from the initial position to the maximum stroke position until the reaction vessel receiving seat 2 is at the maximum stroke position. During this period, the first elastic member 31 is further compressed until the first elastic member 31 is further compressed into the second state. As the driving member 41 continues to move in the first direction, during the transition of the second elastic member 34 from the third state to the fourth state, the passive tooth on the driven mechanism 322 gradually increases the force on the active tooth on the main driving mechanism 331, the main stop surface and the stopped surface 3222 separate, the second elastic member 34 is further compressed, and the transition from the third state to the fourth state occurs.
[0116] In step S3, when the driving member 41 continues to move in the first direction, the first elastic member 31 cannot be further compressed. At this time, the active member 33 moves in the fourth direction, which is opposite to the third direction of the rotating member 42. The second elastic member 34 gradually changes from the fourth state to the third state. During this process, the first elastic member 31 provides a thrust to the reaction container accommodating seat 2, moving it from the maximum stroke position to the initial position. The reaction container accommodating seat 2 moves to the initial position, and the reaction container accommodating seat 2 drives the connecting rotating member 323 to move in the first direction. The connecting rotating member 323 drives the driven mechanism 322 to rotate in the first direction. This continues until the reaction container accommodating cavity moves from the maximum stroke position to the initial position, thus completing one mixing action. In this embodiment, the first direction is counterclockwise, the second direction is clockwise, the third direction is upward, and the fourth direction is downward.
[0117] During steps S2 to S3, the material inside the reaction vessel accommodating seat 2 undergoes one reciprocating motion, resulting in one mixing action. As the driving component 41 continues to rotate in the first direction, the mixing device continuously switches between steps S2 and S3, achieving multiple mixing of the material inside the reaction vessel accommodating seat 2.
[0118] The specific steps of the reset procedure are as follows:
[0119] (1) If the reaction vessel accommodating seat 2 is already in the initial position, then the driving member 41 rotates in the second direction, the driving member 41 drives the rotating member 42 to rotate in the second direction, and the rotating member 42 drives the active member 33 to rotate in the second direction.
[0120] At this time, the driven mechanism 322 does not rotate, and the rotational speed of the main drive mechanism 331 in the second direction is greater than that of the driven mechanism 322 in the second direction. The first elastic element 31 remains in the first state. As the drive member 41 continues to rotate in the fourth direction, the force of the driven mechanism 322 on the main drive mechanism 331 causes the second elastic element 34 to repeatedly switch between the third and fourth states. The main stop surface 3312 of the active tooth on the main drive mechanism 331 and the stop surface 3222 of the passive tooth on the driven mechanism 322 repeatedly switch between contact and separation.
[0121] (2) If the reaction vessel accommodating seat 2 is not in the initial position, then the reaction vessel accommodating seat 2 is in the maximum stroke position or between the maximum stroke position and the initial position. The driving member 41 rotates in the second direction, and the driving member 41 drives the rotating member 42 to rotate in the second direction. The rotating member 42 drives the driving member 33 to rotate in the second direction. The driven mechanism 322 is subjected to the force of the main driving mechanism 331 on the driven mechanism 322 in the second direction and the force of the first elastic member 31 on the driven mechanism 322 in the first direction. Under the action of the resultant force, the reaction vessel accommodating seat 2 eventually returns to the initial position.
[0122] An automated analysis system includes the aforementioned mixing device, sample injection device, reaction vessel loading device, incubation device, reagent storage device, pipetting device, washing device, detection device, and reaction vessel disposal device, as well as a control device. The sample injection device delivers samples into the automated analysis system; the reaction vessel loading device delivers reaction vessels into the system; the pipetting device removes reagents and reaction vessels; the reagent storage device provides reagents for sample detection; the incubation device accelerates the reaction rate between the sample and reagents; the washing device removes interfering substances from the reaction vessel; the detection device detects complexes formed by the sample and reagents; the reaction vessel disposal device discards the completed reaction vessel; and the control device controls the operation of the mixing device, sample injection device, reaction vessel loading device, incubation device, reagent storage device, pipetting device, washing device, detection device, and reaction vessel disposal device.
[0123] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of this application, and are not intended to limit them. Although this application has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some or all of the technical features therein. Such modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of this application.
Claims
1. A mixing device, characterized in that, include: A frame, on which guide components are provided; The reaction vessel housing is slidably mounted on the guide member and has an initial position and a maximum stroke position. It includes a receiving cavity and an eccentric cavity disposed opposite to it. The clutch assembly includes a first elastic member that forces the reaction vessel housing to slide from the maximum stroke position toward the initial position, a passive member with an eccentric mechanism at one end and a driven mechanism at the other end, an active member with a main drive mechanism at one end and a connecting mechanism at the other end, and a second elastic member, wherein the eccentric mechanism is housed in the eccentric cavity. A drive assembly includes a drive member and a rotating member driven to rotate by the drive member, the connecting mechanism being slidably disposed on the rotating member, and the second elastic member forcing the active member to move toward the passive member so that the main drive mechanism abuts against the driven mechanism. During the rotation of the active member along the first direction with the rotating member, the eccentric mechanism abuts against the eccentric cavity to cause the reaction vessel accommodating seat to reciprocate between the initial position and the maximum stroke position; during the rotation of the active member along the second direction opposite to the first direction with the rotating member, the reaction vessel accommodating seat moves toward the initial position or remains in the initial position.
2. The mixing device according to claim 1, characterized in that, The driven mechanism is provided with a sliding surface and a blocking surface, and the main driving mechanism is provided with a main sliding surface and a main blocking surface. When the reaction vessel accommodating seat moves from the initial position to the maximum stroke position, the blocking surface abuts against the main blocking surface. The passive component also includes a connecting rotating component, one end of which is connected to the eccentric mechanism and the other end of which is connected to the driven mechanism.
3. The mixing device according to claim 2, characterized in that, The eccentric mechanism includes a rotating wheel that abuts against the eccentric cavity and an eccentric protrusion that is fixedly connected to the axis of the rotating wheel. The eccentric protrusion is disposed at one end of the connecting rotating member.
4. The mixing device according to claim 3, characterized in that, The frame also includes a base plate, a first side plate and a second side plate fixedly disposed on the base plate, and a top plate fixedly disposed on the first side plate and the second side plate; The base plate is provided with a drive component mounting hole, the top plate is provided with a clutch component mounting hole, and the connecting rotating component is rotatably disposed in the clutch component mounting hole.
5. The mixing apparatus according to claim 4, characterized in that, There is a gap between the top plate and the bottom plate, and the driven mechanism, the main drive mechanism, the connecting mechanism and the second elastic member are disposed in the gap; one end of the second elastic member abuts against the bottom plate and the other end abuts against the connecting mechanism.
6. The mixing apparatus according to claim 5, characterized in that, The rotating component is rotatably disposed within the mounting hole of the drive assembly, and the second elastic component is sleeved outside the rotating component.
7. The mixing apparatus according to claim 4, characterized in that, The frame also includes a third side plate and a fourth side plate, the third side plate and the fourth side plate being disposed opposite to each other, and the third side plate and the fourth side plate being fixedly disposed on both sides of the top plate and not parallel to the first side plate or the second side plate; One end of the guide is fixed to the third side plate, and the other end opposite to one end of the guide is fixed to the fourth side plate; One end of the first elastic member abuts against the third side plate or the fourth side plate, and the other end opposite to one end of the first elastic member abuts against the reaction vessel housing.
8. The mixing apparatus according to claim 7, characterized in that, The first elastic element is a compression spring. The first elastic element has a first compression state and a second compression state. When the first elastic element is in the second compression state, it is further compressed relative to when it is in the first compression state. The second elastic element is a compression elastic element, and the second elastic element has a third compression state and a fourth compression state. When the second elastic element is in the fourth compression state, it is further compressed compared to when the second elastic element is in the third state. When the reaction vessel housing is at its maximum stroke position, the first elastic element is in a second compression state; When the reaction vessel is in the initial position, the first elastic element is in a first compression state and the second elastic element is in a third compression state.
9. A mixing method, applied to the mixing apparatus according to any one of claims 1-8, characterized in that, include: In the mixing step, the driving member drives the rotating member to rotate along the first direction, and the active member rotates with the rotating member; In the reset step, the driving component drives the rotating component to rotate along the second direction; During the rotation of the active component along the first direction with the rotating component, the eccentric mechanism abuts against the eccentric cavity to cause the reaction vessel accommodating seat to reciprocate between the initial position and the maximum stroke position; during the rotation of the active component along the second direction with the rotating component, the reaction vessel accommodating seat moves toward the initial position or remains at the initial position.
10. An automatic analysis system, characterized in that, The mixing apparatus includes any one of claims 1-8.
Citation Information
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