A stem cell cold storage box

Abstract

The application relates to the technical field of stem cells, and discloses a stem cell cold storage box, which comprises a storage box body, a cold storage cavity is arranged in the storage box body, a storage fixing structure is slidably arranged in the cold storage cavity, the storage fixing structure comprises a structure mounting plate, structure grooves are arranged in the structure mounting plate, an installation bottom plate is rotatably arranged in the structure grooves, and clamping arc pieces are arranged on the installation bottom plate; the stem cell cold storage box is provided with a cold storage system, a single-pipe fixing structure is arranged to fix a storage pipe containing stem cells, a low-temperature control system is composed of a liquid nitrogen temperature control structure and an electric refrigeration system, the low-temperature control system and the single-pipe fixing structure are combined to control the temperature of the corresponding storage pipe, so that the temperature of the storage pipe is controlled through the cooperation of the two during normal storage, and the consumption of liquid nitrogen is reduced.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of stem cell, in particular to a stem cell cold storage box. BACKGROUND

[0002] Stem cells are cells that have the ability to self-renew and proliferate. With the development of medicine, the extraction and application technology of stem cells have developed, and the extraction of stem cells plays an important role in the treatment of damaged tissues and organs in modern medicine. The storage of stem cells needs to be stored and transferred at low temperature to inhibit the activity of stem cells. Therefore, liquid nitrogen is often used in medicine to store stem cells. The conventional cold storage box creates a low-temperature environment for the whole box body by using liquid nitrogen, which consumes a lot of liquid nitrogen and causes waste. SUMMARY

[0003] The purpose of the present application is to provide a stem cell cold storage box to overcome the above-mentioned defects in the prior art.

[0004] The present application is realized by the following technical solutions.

[0005] The stem cell cold storage box comprises a storage box body, a cold storage cavity is arranged in the storage box body, a storage fixing structure is arranged in the cold storage cavity in an array and is slidably installed, the storage fixing structure comprises a structure mounting plate, the structure mounting plate is provided with a structure groove in an array, an installation bottom plate is rotatably installed in the structure groove, a clamping arc piece is installed in the installation bottom plate in an array, a liquid nitrogen output strip is installed at the top of the clamping arc piece, the liquid nitrogen output strip is provided with an output spray ring capable of outputting liquid nitrogen, the clamping arc piece is provided with a liquid nitrogen transmission cavity, the liquid nitrogen transmission cavity is communicated with the output spray ring, a water-fitting capsule is installed on the inner wall of the clamping arc piece, a storage tube is arranged in the clamping arc piece, a receiving rubber body is slidably installed on the installation bottom plate, the installation bottom plate is provided with a transmission groove, the transmission groove is communicated with the liquid nitrogen transmission cavity, the transmission groove is provided with a control communication groove, a sealing plug is slidably installed in the control communication groove, a front sealing plate is installed on the structure mounting plate, a rear sealing plate is installed on the structure mounting plate, the cold storage cavity is provided with an opening groove, and a sealing box door is rotatably installed in the opening groove.

[0006] Further technical solutions, a refrigeration liquid cavity is arranged in the storage box body, the refrigeration liquid cavity contains liquid water, a semiconductor refrigeration piece is installed in the refrigeration liquid cavity, a water delivery plate is installed on the lower side of the structure mounting plate, the water delivery plate is communicated with a water delivery pipe, the water delivery pipe is communicated with the refrigeration liquid cavity, the clamping arc piece is provided with a water communication cavity, the water communication cavity is communicated with the water-fitting capsule, the water communication cavity is communicated with an input pipe, the input pipe is communicated with the water delivery plate, the water communication cavity is communicated with a return pipe, and the return pipe is communicated with the refrigeration liquid cavity.

[0007] Further technical solutions, the storage box is installed with an output pump, the output pump is communicated with two communication valves, the left side communication valve is communicated with the refrigerant liquid cavity.

[0008] Further technical solutions, the storage box is detachably installed with a liquid nitrogen storage plate, the right side communication valve is communicated with the liquid nitrogen storage plate, the control communication groove is communicated with a liquid nitrogen input pipe, and the liquid nitrogen input pipe is communicated with the liquid nitrogen storage plate at the end.

[0009] Further technical solutions, the mounting bottom plate is provided with a transmission sliding groove, a support rod is slidably installed in the transmission sliding groove, and the support rod is installed at the end of the support rod.

[0010] Further technical solutions, the control communication groove is provided with a side wall sliding groove, the sealing plug is slidably installed in the side wall sliding groove, a sealing spring is installed in the side wall sliding groove, and a transmission wire is connected to the end of the sealing plug.

[0011] Further technical solutions, the storage box is installed with a top cover, and the top cover is rotatably installed with a handheld part.

[0012] Further technical solutions, the structure groove is installed with a rotating connecting piece, the rotating connecting piece is rotatably installed with a support shaft, and the support shaft is connected to the mounting bottom plate at the end.

[0013] The beneficial effects of the application are as follows:

[0014] The stem cell cold storage box of the application is fixed by the single pipe fixing structure through the setting of the cold storage system, the low-temperature control system is composed of a liquid nitrogen temperature control structure and an electric refrigeration system, the temperature control effect of the corresponding storage pipe is realized by the output effect of the low-temperature control system cooperating with the single pipe fixing structure, so that the temperature control of the storage pipe is realized through the cooperation of the two in the conventional storage process, thereby reducing the consumption of liquid nitrogen, and the liquid nitrogen is output by being gasified and adhered to the pipe wall, so that the storage pipe is first cooled, and the low-temperature radiation of the liquid nitrogen output forms a low-temperature environment in the box, and the conventional cold storage box is cooled by a large amount of input of liquid nitrogen to form a low-temperature environment in the box, so that the storage pipe is cooled to a low temperature, and the refrigeration board is used to greatly reduce the consumption speed of liquid nitrogen, the combination of the two refrigeration systems and the single refrigeration effect are used to avoid the problems that the battery power is consumed or the liquid nitrogen is consumed in the transportation link of the conventional cold storage box, and the low-temperature control effect is lost, so that the stem cells are consumed.

[0015] The stem cell cold storage box of the present application is provided with a cold storage system, the single-tube fixing structure is provided with a clamping arc piece for surrounding and fixing the storage tube, the inner side of the clamping arc piece is provided with a matching capsule, the capsule is filled with low-temperature water through the electric refrigeration effect to achieve low-temperature control effect on the storage tube, the liquid nitrogen output structure is arranged on the upper side of the clamping arc piece, and the liquid nitrogen is output to the outer wall of the storage tube to achieve low-temperature control effect on the storage tube and the matching capsule, the refrigeration effect of the liquid nitrogen gas mist output and the electric refrigeration on the matching capsule can be simultaneously or individually performed, so as to avoid the problem that the single consumption of power or liquid nitrogen refrigeration resources is exhausted to cause the refrigeration effect of the box body to be lost, and the single-tube fixing structure is provided with a communication control structure, the communication structure controls the communication and interruption of the liquid nitrogen flow guide pipeline by the different weights of the stem cell tube and the empty tube, so as to achieve the effect of no liquid nitrogen output to the empty storage tube, thereby further reducing the loss and waste of liquid nitrogen.

[0016] The stem cell cold storage box of the present application is provided with a cold storage system, the single-tube fixing structure is provided with a clamping arc piece for surrounding and fixing the storage tube, the inner side of the clamping arc piece is provided with a matching capsule, the capsule is filled with low-temperature water through the electric refrigeration effect to achieve low-temperature control effect on the storage tube, the liquid nitrogen output structure is arranged on the upper side of the clamping arc piece, and the liquid nitrogen is output to the outer wall of the storage tube to achieve low-temperature control effect on the storage tube and the matching capsule, the refrigeration effect of the liquid nitrogen gas mist output and the electric refrigeration on the matching capsule can be simultaneously or individually performed, so as to avoid the problem that the single consumption of power or liquid nitrogen refrigeration resources is exhausted to cause the refrigeration effect of the box body to be lost, and the single-tube fixing structure is provided with a communication control structure, the communication structure controls the communication and interruption of the liquid nitrogen flow guide pipeline by the different weights of the stem cell tube and the empty tube, so as to achieve the effect of no liquid nitrogen output to the empty storage tube, thereby further reducing the loss and waste of liquid nitrogen. BRIEF DESCRIPTION OF DRAWINGS

[0017] In order to more clearly illustrate the technical solutions of the embodiments of the present application or the prior art, the following will briefly introduce the drawings needed to be used in the embodiments or the prior art description. Obviously, the drawings in the following description are only some embodiments of the present application, and other drawings can also be obtained by those skilled in the art without any creative effort.

[0018] The present application will be further described below in combination with the drawings and embodiments.

[0019] Figure 1 is a schematic diagram of the overall structure of the present application;

[0020] Figure 2 is Figure 1 is an enlarged schematic diagram of the structure of the storage fixing structure 15 in the present application;

[0021] Figure 3 is Figure 2 is an enlarged structure schematic diagram of A in the present application;

[0022] Figure 4 is Figure 3Enlarged structural diagram at point B;

[0023] Figure 5 yes Figure 3 A magnified structural diagram at point C. Detailed Implementation

[0024] The following is combined with Figures 1-5 The present invention will be described in detail below. For ease of description, the directions referred to below are defined as follows: the directions of up, down, left, right, front, and back mentioned below are the same as... Figure 1 The directions of the projection relationship are consistent in all directions: up, down, left, right, front, and back.

[0025] A stem cell cold storage box, as described in Figures 1-5, includes a storage box body 11. A cold storage cavity 12 is provided within the storage box body 11. A storage fixing structure 15 is slidably mounted in an array within the cold storage cavity 12. The storage fixing structure 15 includes a structural mounting plate 24. The structural mounting plate 24 has an array of structural grooves 29. A mounting base plate 37 is rotatably mounted on the structural grooves 29. The mounting base plate 37 has an array of locking arc plates 30. A liquid nitrogen output strip 34 is mounted on the top of the locking arc plates 30. The liquid nitrogen output strip 34 has an output spray ring 53 capable of outputting liquid nitrogen. The locking arc plates 30 have a liquid nitrogen transmission cavity 31, which is connected to... The output spray ring 53, the inner wall of the locking arc plate 30 is equipped with a water-fillable fitting bag 33, the locking arc plate 30 is provided with a storage tube 35, the mounting base plate 37 is slidably mounted with a receiving rubber body 36, the mounting base plate 37 is provided with a transmission groove 43, the transmission groove 43 is connected to the liquid nitrogen transmission chamber 31, the transmission groove 43 is provided with a control communication groove 45, the control communication groove 45 is slidably mounted with a sealing plug 47, the structural mounting plate 24 is equipped with a front sealing plate 23, the structural mounting plate 24 is equipped with a rear sealing plate 27, the cold storage chamber 12 is provided with an opening groove 14, the opening groove 14 is rotatably mounted with a sealing box door 13.

[0026] During operation, the storage tube 35 containing stem cells is placed on top of the receiving rubber body 36. The weight of the storage tube 35 is higher than that of the empty storage tube 35. Under the elastic connection structure, the receiving rubber body 36 moves downwards. The transmission structure causes the sealing plug 47 to rise without blocking the liquid nitrogen input pipe 42. Thus, during storage, liquid nitrogen can only be input into the connected liquid nitrogen input pipe 42, achieving cooling output only to the storage tube containing stem cells. Liquid nitrogen mist is transmitted through the liquid nitrogen transmission chamber 31 and sprayed from top to bottom onto the storage tube by the output spray ring 53. The liquid is cooled by an electro-cooling structure and input to the bonding capsule 33, causing the bonding capsule 33 to adhere to the outer wall of the storage tube 35 for low-temperature maintenance. This achieves the effect through two control mechanisms. The combined cooling effect reduces liquid nitrogen consumption, and the liquid nitrogen spray also lowers the temperature of the attached capsule 33, thus making the low-temperature control effect more durable and avoiding the problem of the chamber losing its cooling effect due to the exhaustion of power or liquid nitrogen cooling resources. When taking it out, the sealed door 13 is opened and the corresponding storage fixing structure 15 is pulled out, so that the rear sealing plate 27 is placed in the sealing position of the opening slot 14, so that the cold storage chamber 12 is kept sealed, reducing the amount of low-temperature gas escaping and maintaining the low-temperature environment inside the cold storage chamber 12. At the same time, after being pulled out, the attached capsule 33 and the output spray ring 53 continuously control the low temperature of the external storage tube 35, thereby avoiding the problem of multiple tubes being placed in the external environment at the same time, which would cause the low-temperature tubes to heat up rapidly and affect the activity of stem cells.

[0027] Preferably, the storage box 11 is provided with a cooling liquid chamber 16 containing liquid water. A semiconductor cooling chip 17 is installed in the cooling liquid chamber 16. A water supply plate 25 is installed on the lower side of the structural mounting plate 24. The water supply plate 25 is connected to a water supply pipe 26, which is connected to the cooling liquid chamber 16. The locking arc plate 30 is provided with a water communication chamber 32, which is connected to the fitting capsule 33. The water communication chamber 32 is connected to an input pipe 38, which is connected to the water supply plate 25. The water communication chamber 32 is connected to a return pipe 39, which is connected to the cooling liquid chamber 16.

[0028] The liquid in the cooling liquid chamber 16 is cooled by the semiconductor cooling chip 17. The output pump fills the bonding capsule 33 with the cryogenic liquid. The cryogenic liquid is circulated through the input pipe 38 and the return pipe 39, thereby keeping the bonding capsule 33 at the set low temperature.

[0029] Preferably, the storage box 11 is equipped with an output pump 20, which is connected to two connecting valves 22, with the left connecting valve 22 connected to the refrigerant liquid chamber 16.

[0030] By starting the output pump 20 and connecting the left connecting valve 22, the low-temperature water in the refrigeration liquid chamber 16 is circulated.

[0031] Preferably, the storage box 11 is detachably equipped with a liquid nitrogen storage plate 21, the connecting valve 22 on the right side is connected to the liquid nitrogen storage plate 21, the control connecting groove 45 is connected to a liquid nitrogen input pipe 42, and the end of the liquid nitrogen input pipe 42 is connected to the liquid nitrogen storage plate 21.

[0032] Through the right-side connecting valve 22, with the output pump 20 started, the liquid nitrogen mist in the liquid nitrogen storage plate 21 is transmitted by the liquid nitrogen input pipe 42 and output to the outer wall of the storage pipe 35 through the output spray ring 53.

[0033] Preferably, the mounting base plate 37 is provided with a transmission groove 50, a support rod 51 is slidably installed in the transmission groove 50, the receiving rubber body 36 is installed at the end of the support rod 51, and a support spring 52 is installed on the support rod 51.

[0034] By placing the storage tube 35 containing stem cells on the receiving rubber body 36, gravity presses the support rod 51 downwards, achieving the effect of transmission and lowering the center of gravity of the storage tube 35.

[0035] Preferably, the control communication groove 45 has a side wall groove 46 on its side wall, the sealing plug 47 is slidably installed in the side wall groove 46, a sealing spring 49 is installed in the side wall groove 46, the end of the sealing plug 47 is connected to a transmission line 48, and the end of the transmission line 48 is connected to the support rod 51.

[0036] The support rod 51 slides down, causing the transmission line 48 to loosen, which in turn causes the sealing plug 47 to move up, thereby connecting the control communication groove 45.

[0037] Preferably, the storage box 11 is equipped with a top cover 18, and the top cover 18 is rotatably equipped with a hand handle 19.

[0038] The handle 19 facilitates the movement and retrieval of the box.

[0039] Preferably, the structural groove 29 is equipped with a rotating connector 40, and the rotating connector 40 is rotatably mounted with a support shaft 41, the end of which is connected to the mounting base plate 37.

[0040] A torsion spring is installed inside the rotating connector 40 to keep the support shaft 41 vertical, thereby reducing the impact of vibration on the storage tube 35.

[0041] The above embodiments are only for illustrating the technical concept and features of the present invention, and are intended to enable those skilled in the art to understand and implement the present invention. They should not be construed as limiting the scope of protection of the present invention. All equivalent changes or modifications made in accordance with the spirit and essence of the present invention should be covered within the scope of protection of the present invention.

Claims

1. A stem cell cold storage box, comprising a storage box body, characterized in that: The storage box contains a cold storage cavity, within which a storage fixing structure is slidably mounted in an array. The storage fixing structure includes a structural mounting plate, an array of structural grooves on the mounting plate, a mounting base plate rotatably mounted on the structural grooves, an array of locking arc plates on the mounting base plate, a liquid nitrogen output strip mounted on the top of the locking arc plates, an output spray ring for outputting liquid nitrogen on the liquid nitrogen output strip, a liquid nitrogen transmission cavity on the locking arc plates, a water-fillable fitting capsule mounted on the inner wall of the locking arc plates, a storage tube inside the locking arc plates, a receiving rubber body slidably mounted on the mounting base plate, a transmission groove on the mounting base plate communicating with the liquid nitrogen transmission cavity, a control communication groove on the transmission groove, a sealing plug slidably mounted on the control communication groove, a front sealing plate mounted on the structural mounting plate, a rear sealing plate mounted on the structural mounting plate, and an opening groove on the cold storage cavity, with a sealed door rotatably mounted on the opening groove. The mounting base plate is provided with a transmission groove, a support rod is slidably installed in the transmission groove, the receiving rubber body is installed at the end of the support rod, and a support spring is installed on the support rod; The control communication channel has a side wall groove, on which the sealing plug is slidably installed. A sealing spring is installed inside the side wall groove, and a transmission line is connected to the end of the sealing plug. The end of the transmission line is connected to the support rod.

2. The stem cell cold storage box according to claim 1, characterized in that: The storage box contains a cooling liquid chamber containing liquid water and a semiconductor cooling chip. A water supply plate is mounted on the lower side of the structure mounting plate, and the water supply plate is connected to a water supply pipe, which is connected to the cooling liquid chamber. The locking arc plate has a water communication chamber, which is connected to the fitting capsule. The water communication chamber is connected to an input pipe, which is connected to the water supply plate. The water communication chamber is connected to a return pipe, which is connected to the cooling liquid chamber.

3. A stem cell cold storage box according to claim 2, characterized in that: The storage box is equipped with an output pump, which is connected to two connecting valves. The connecting valve on the left is connected to the refrigerant liquid chamber.

4. A stem cell cold storage box according to claim 3, characterized in that: The storage box is detachably equipped with a liquid nitrogen storage plate. The connecting valve on the right side is connected to the liquid nitrogen storage plate. The control connecting groove is connected to a liquid nitrogen input pipe, and the end of the liquid nitrogen input pipe is connected to the liquid nitrogen storage plate.

5. A stem cell cold storage box according to claim 1, characterized in that: The storage box is equipped with a top cover, and a hand-held part is rotatably mounted on the top cover.

6. A stem cell cold storage box according to claim 1, characterized in that: The structural groove is fitted with a rotating connector, and the rotating connector is rotatably mounted with a support shaft, the end of which is connected to the mounting base plate.

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