A sample cup processing device

Abstract

The present invention provides a sample cup processing device, which includes a base, a first guide rail and a tube filling assembly. A mechanical clamp is provided on the top of the base, and a supporting platform is provided on one side of the mechanical clamp; the first guide rail is mounted above the base, and a transfer robot and a horizontal plate are slidably provided on the first guide rail, and a driving mechanism is also provided on the mounting frame. Four vertical plates are slidably provided on the side wall of the horizontal plate, and a first driving assembly is provided on the side wall of the horizontal plate away from the vertical plate, and a liquid suction and discharge assembly is slidably provided on the side wall of each vertical plate, and a suction head is detachably installed on the liquid suction and discharge assembly, and a second driving assembly is provided on each vertical plate; the tube filling assembly is arranged on the top of the base, and the tube filling assembly supplies suction heads to the liquid suction and discharge assembly, which solves the problem in the prior art that when sampling sample liquids in multiple sampling tubes at the same time, it is impossible to repeat sampling a certain abnormal sampling tube separately.

Description

Technical Field

[0001] The present invention relates to the technical field of sample detection, and in particular to a sample cupping processing device. Background Art

[0002] During the testing process of the sample liquid in the sampling tube, the sample liquid in the sampling tube needs to be taken out first, so as to facilitate the staff to test the sample liquid. At present, a cup processing device is usually used to cup the sample liquid in the tube into a deep-well plate, such as the SRO-4000 cup processing device produced by Maikino (Chongqing) Gene Technology Co., Ltd. or the BK-PR48 cup processing device produced by Shandong Bo Ke Scientific Instrument Co., Ltd., but these devices can usually only sample one sampling tube at a time. Although the cup processing devices produced by some companies can sample multiple sampling tubes at a time, because all the pipette heads are driven by only one motor, once a certain aspiration and discharge device has insufficient liquid volume, other aspiration and discharge devices need to be handled together. The abnormal problem of the abnormal pipette head cannot be handled separately, and the aspiration and discharge device that has no abnormality will also repeat the sampling, affecting the quality of the sampling. Summary of the Invention

[0003] In response to the deficiencies in the prior art, the present invention provides a sample cupping processing device, which solves the problem in the prior art that when sampling sample liquids in multiple sampling tubes at the same time, it is impossible to repeat sampling of an abnormal sampling tube alone.

[0004] According to an embodiment of the present invention, a sample cup processing device includes a base, a first guide rail and a tube filling assembly, the top of the base is provided with a mechanical clamp for fixing the sample tube on the base, and one side of the mechanical clamp is provided with a supporting platform for placing the sampling tube; the first guide rail is mounted above the base through a mounting frame, and a transfer robot and a cross plate are slidably provided on the first guide rail, and the mounting frame is also provided with a driving mechanism for driving the transfer robot and the cross plate to slide on the first guide rail respectively, and the transfer robot is used to clamp the sampling tube and transport it to the mechanical clamp. Four vertical plates are slidably provided on the side walls of the horizontal plate, and the length direction of each vertical plate is perpendicular to the length direction of the horizontal plate. A first driving assembly for driving the vertical plate to slide on the horizontal plate is provided on the side wall of the horizontal plate away from the vertical plate, and a suction and discharge assembly for sucking or discharging the sampling liquid in the sampling tube is slidably provided on the side wall of each vertical plate, and a suction head is detachably mounted on the suction and discharge assembly, and a second driving assembly for driving the corresponding suction and discharge assembly to move up and down is provided on each vertical plate; the pipe filling assembly is arranged on the top of the base, and the pipe filling assembly supplies the suction head to the suction and discharge assembly.

[0005] Compared with the prior art, the present invention has the following beneficial effects: the sampling tube transferred by the transfer robot is clamped by a mechanical clamp, and then the vertical plate makes the liquid suction and discharge component directly above the sampling tube under the action of the first drive component, and the liquid suction and discharge component on each vertical plate is inserted into the sampling tube to absorb liquid under the drive of the second drive component. When a liquid suction and discharge component aspirates abnormally, such as insufficient liquid aspiration, the liquid suction and discharge component on the vertical plate can be individually controlled to repeat sampling of the sampling tube, so that there is no need to repeat sampling of other sampling tubes that are normally sampled, thereby ensuring the sampling efficiency and the quality of the absorbed sample liquid.

[0006] Furthermore, the first drive assembly includes: a first synchronous wheel, there are four first synchronous wheels, the four first synchronous wheels are symmetrically and rotatably arranged at both ends of the horizontal plate in groups of two, a first conveyor belt is sleeved between every two first synchronous wheels at the same horizontal height, two clamping blocks are fixed on each of the first conveyor belts, two through slots are provided on the horizontal plate, one end of each clamping block extends out of the through slot and is fixedly connected to the vertical plate, and two first motors that drive the corresponding first synchronous wheels to rotate are also provided on the side walls of the horizontal plate.

[0007] Furthermore, each of the second drive components includes: a second synchronous wheel, there are two second synchronous wheels and both are rotatably arranged at the two ends of each vertical plate, a second conveyor belt is sleeved between the two second synchronous wheels, each second conveyor belt is fixedly connected to a liquid suction and discharge component through a connecting piece, and a second motor is provided on the side wall of each vertical plate to drive the corresponding second synchronous wheel to rotate.

[0008] Furthermore, each of the liquid suction and discharge components includes: a mounting block and a piston rod, each of the liquid suction and discharge components includes: a mounting block and a piston rod, the mounting block is fixedly connected to the connecting piece, a mounting cavity is provided inside the mounting block, one end of the piston rod is slidably connected to the mounting cavity, a liquid suction and discharge head is provided at the bottom of the mounting block, the liquid suction and discharge head is communicated with the mounting cavity, a third driving component for driving the piston rod to rise or fall is also provided at the top of the mounting block, and a tube removal component is also provided at the bottom of the mounting block to facilitate removal of the used suction head.

[0009] Furthermore, the third driving component includes: a driving motor, which is fixedly arranged on the side wall of the corresponding vertical plate, a screw rod is provided on the output end of the driving motor, a push block is provided on the screw rod, the side wall of the push block is slidingly connected to the side wall of the vertical plate, and the bottom of the push block is fixedly connected to the end of the piston rod located outside the mounting cavity.

[0010] Furthermore, the tube removal assembly includes: a push rod, one end of which is provided with a push plate after passing through the mounting cavity from top to bottom, a through hole being opened on the push plate, and the push plate is slidingly connected to the suction and discharge head through the through hole, and a return spring is also provided between the push rod and the mounting block, and the top end of the push rod is located directly below the push block.

[0011] Furthermore, the tube filling assembly includes: a movable plate, which is arranged on the top of the base through a second guide rail, and the top of the movable plate is provided with a tube filling rack for placing pipette tips and a waste box for placing discarded pipette tips, and the top of the movable plate is also provided with a deep well plate for receiving the sample liquid discharged by the suction and discharge assembly, and the top of the base is provided with a conveyor belt for driving the movable plate to move on the second guide rail. BRIEF DESCRIPTION OF THE DRAWINGS

[0012] Figure 1 Schematic diagram of the overall structure of an embodiment of the present invention.

[0013] Figure 2 Schematic diagram of the installation of horizontal and vertical plates according to an embodiment of the present invention.

[0014] Figure 3 This is a schematic diagram of the installation of the horizontal plate and the vertical plate from another perspective of an embodiment of the present invention.

[0015] Figure 4 This is a structural diagram of the liquid suction and discharge components according to an embodiment of the present invention.

[0016] In the above drawings: 1. base; 2. mechanical gripper; 3. load-bearing platform; 4. first guide rail; 5. mounting frame; 6. transfer robot; 7. horizontal plate; 8. vertical plate; 9. suction head; 10. first synchronous wheel; 11. first conveyor belt; 12. pressing block; 13. first motor; 14. second synchronous wheel; 15. second conveyor belt; 16. second motor; 17. mounting block; 18. piston rod; 19. suction and discharge head; 20. drive motor; 21. screw; 22. push block; 23. push rod; 24. push plate; 25. reset spring; 26. movable plate; 27. second guide rail; 28. pipe filling rack; 29. ​​waste box; 30. deep hole plate; 31. connecting piece. DETAILED DESCRIPTION

[0017] The technical solutions of the present invention are further described below with reference to the accompanying drawings and embodiments.

[0018] like Figure 1As shown in FIG3 , an embodiment of the present invention proposes a sample cup processing device, comprising a base 1, a first guide rail 4 and a tube filling assembly. The top of the base 1 is provided with a mechanical gripper 2 for fixing the sample tube on the base 1, and one side of the mechanical gripper 2 is provided with a carrier 3 for placing the sampling tube; the first guide rail 4 is erected above the base 1 through a mounting frame 5, and a transfer manipulator 6 and a cross plate 7 are slidably provided on the first guide rail 4. The mounting frame 5 is also provided with a driving mechanism for driving the transfer manipulator 6 and the cross plate 7 to slide on the first guide rail 4 respectively. The transfer manipulator 6 is used to clamp the sampling tube and transport it to the machine On the mechanical clamp 2, four vertical plates 8 are slidably provided on the side walls of the horizontal plate 7, and the length direction of each vertical plate 8 is perpendicular to the length direction of the horizontal plate 7. The side walls of the horizontal plate 7 facing away from the vertical plates 8 are provided with a first driving component that drives the vertical plates 8 to slide on the horizontal plate 7, and the side walls of each vertical plate 8 are slidably provided with a suction and discharge component for sucking or discharging the sampling liquid in the sampling tube, and a suction head 9 is detachably installed on the suction and discharge component, and a second driving component that drives the corresponding suction and discharge component to move up and down is provided on each vertical plate 8; the pipe filling component is arranged on the top of the base 1, and the pipe filling component supplies the suction and discharge component with a suction head 9. During operation, the sampling tube carrier with multiple sampling tubes is placed on the supporting platform 3, and the transfer robot 6 clamps the sampling tube placed on the supporting platform 3 and then transports it to the mechanical clamp 2. After the mechanical clamp 2 clamps the sampling tube, the transfer robot 6 moves to the side. At this time, the horizontal plate 7 moves to the top of the mechanical clamp 2 under the drive of the driving mechanism. Then, the first driving component moves each vertical plate 8 to the appropriate position, and the second driving mechanism drives the suction and drainage components on the vertical plate 8 to descend, so that the suction head 9 on the suction and drainage component is inserted into the sampling tube and sampling is performed. After the suction and drainage component has completed sampling, the second driving component drives the drainage component to a suitable height to prevent the suction head 9 from touching the external device during the movement. At this time, the first driving component drives the suction and drainage component again. The spacing between each vertical plate 8 is changed so that the suction head 9 on each suction and discharge component corresponds to the hole of the deep-well plate 30. Then, the suction and discharge component is driven by the second driving component to drop to a suitable height so that the suction head 9 is inserted into the deep-well plate 30 for drainage. After the drainage is completed, the suction and discharge group will remove the suction head 9 and reinstall the suction head 9 in cooperation with the tube filling component, thereby completing the cupping of the sample liquid in the sampling tube. If a certain suction and discharge component encounters sampling abnormality, the second driving component of the suction and discharge component can be controlled separately to work so that the suction head 9 is reinserted into the sampling tube for re-sampling. In order to make the vertical plate 8 slide on the horizontal plate 7 and the suction and discharge component move up and down on the vertical plate 8 more stable, corresponding tracks and slide grooves can be set between the two sliding connections.Specifically, the nut of the sampling tube can be unscrewed in advance, or the sampling tube can be fixed by a mechanical clamp 2 and then rotated by a transfer robot 6 with a rotation function to perform the capping operation. The driving mechanism for driving the transfer robot 6 and the cross plate 7 to move on the first guide rail 4 is a conventional means, which can be driven by a hydraulic cylinder or a motor-driven chain transmission, or the driving method in the Chinese patent document with publication number CN215592565U can be adopted. The structure of the robot can adopt the clamping mechanism in the publication number CN215592565U or the Z-EFG series electric clamp produced by Huiling Technology (Shenzhen) Co., Ltd., which are all existing technologies and will not be described in detail here.

[0019] like Figure 2 —3, further, the first drive component includes: a first synchronous wheel 10, the number of the first synchronous wheels 10 is four, the four first synchronous wheels 10 are symmetrically and rotatably arranged at both ends of the horizontal plate 7 in a group of two, a first conveyor belt 11 is sleeved between every two first synchronous wheels 10 at the same horizontal height, two clamping blocks 12 are fixedly provided on each of the first conveyor belts 11, two through slots are provided on the horizontal plate 7, one end of each clamping block 12 extends out of the through slot and is fixedly connected to the vertical plate 8, and two first motors 13 that drive the corresponding first synchronous wheels 10 to rotate are also provided on the side wall of the horizontal plate 7. During operation, the first motor 13 rotates forward, so that the first motor 13 drives the first synchronous wheel 10 to rotate, thereby rotating the first conveyor belt 11 sleeved between the two first synchronous wheels 10, so that the compression block 12 on the first conveyor belt drives the vertical plate 8 connected thereto to move horizontally on the transverse plate 7, thereby changing the spacing between the vertical plates 8, and then making the liquid suction and discharge components on the vertical plates 8 directly above the sampling tube, which is convenient for sampling. Specifically, the two compression blocks 12 on the same first conveyor belt 11 are respectively fixed on the upper and lower sides of the same first conveyor belt 11, and the distance between the two compression blocks 12 on the same first conveyor belt 11 and the first synchronous wheel 10 closest to them is dynamically equal.

[0020] like Figure 2 As shown in FIG. 3 , further, each of the second drive assemblies includes: a second synchronous wheel 14, two of which are rotatably disposed at both ends of each vertical plate 8, a second conveyor belt 15 being sleeved between the two second synchronous wheels 14, and a liquid suction and discharge assembly being fixedly connected to each second conveyor belt 15 via a connector 31. A second motor 16 is provided on the side wall of each vertical plate 8 to drive the corresponding second synchronous wheel 14 to rotate. During operation, the second motor 16 drives the second synchronous wheel 14 to rotate, thereby causing the second conveyor belt 15 to drive the liquid suction and discharge assembly connected thereto to move up and down in the vertical direction, thereby changing the horizontal height of the suction head 9, thereby facilitating the suction head 9 to be inserted into or removed from the sampling tube, and allowing the suction head 9 to be close to the deep-well plate 30 for drainage.

[0021] like Figure 4 As shown, further, each of the liquid suction and discharge components includes: a mounting block 17 and a piston rod 18, each of the liquid suction and discharge components includes: a mounting block 17 and a piston rod 18, the mounting block 17 is fixedly connected to the connecting piece 31, a mounting cavity is provided inside the mounting block 17, one end of the piston rod 18 is slidably connected to the mounting cavity, a liquid suction and discharge head 19 is provided at the bottom of the mounting block 17, the liquid suction and discharge head 19 is communicated with the mounting cavity, a third driving component for driving the piston rod 18 to rise or fall is also provided at the top of the mounting block 17, and a tube removal component is also provided at the bottom of the mounting block 17 for facilitating the removal of the used suction head 9. When the suction head 9 is inserted into the appropriate position in the sampling tube, the driving assembly is started, and the driving assembly drives the piston rod 18 to move upward, so that the suction and discharge head 19 absorbs the sample liquid through the suction head 9 under the action of negative pressure, and then the horizontal height of the mounting block 17 is lifted to pull the suction head 9 out of the sampling tube, and then the sample liquid is discharged into the deep well plate 30. After the discharge is completed, the mounting block 17 is raised to a horizontal height under the drive of the lifting assembly, and the used suction head 9 is detached from the suction and discharge head 19 under the action of the tube removal assembly.

[0022] like Figure 4 As shown, further, the third drive assembly includes: a drive motor 20, the drive motor 20 is fixedly arranged on the side wall of the corresponding vertical plate 8, a screw rod 21 is provided on the output end of the drive motor 20, a push block 22 is sleeved on the screw rod 21, the side wall of the push block 22 is slidably connected to the side wall of the vertical plate 8, and the bottom of the push block 22 is fixedly connected to the end of the piston rod 18 located outside the installation cavity. When the suction head 9 needs to absorb the sample liquid, the drive motor 20 is started, and the drive motor 20 rotates forward to drive the screw rod 21 to rotate, thereby lifting the push block 22 on the screw rod 21 upward, causing the piston rod 18 to move upward to generate negative pressure, thereby absorbing the sample liquid in the sampling tube, and then the suction head 9 is moved to the top of the deep well plate 30, and the drive motor 20 rotates in the reverse direction to move the piston rod 18 downward to discharge the sample liquid from the suction head 9.

[0023] like Figure 4As shown, further, the tube removal assembly includes: a push rod 23, one end of the push rod 23 is provided with a push plate 24 after passing through the installation cavity from top to bottom, a through hole is opened on the push plate 24, and the push plate 24 is slidably connected to the liquid suction and discharge head 19 through the through hole, and a return spring 25 is further provided between the push rod 23 and the mounting block 17, and the top end of the push rod 23 is located directly below the push block 22. After the sample liquid is discharged into the deep well plate 30, the mounting block 17 is moved to a suitable position. At this time, the drive motor 20 continues to rotate in the reverse direction, so that the push block 22 pushes the push rod 23 to move downward, so that the push plate 24 moves downward along the liquid suction and discharge head 19, so that the push plate 24 squeezes the suction head 9 from the liquid suction and discharge head 19, making it convenient to replace the new suction head 9 for the liquid suction and discharge head 19. Then the drive motor 20 rotates forward to reset, and the push rod 23 also returns to its original position under the action of the return spring 25.

[0024] like Figure 1 As shown, further, the tube filling assembly includes: a movable plate 26, which is arranged on the top of the base 1 through a second guide rail 27, and a tube filling rack 28 for placing the pipette tip 9 and a waste box 29 for placing discarded pipette tips 9 are provided on the top of the movable plate 26. A deep well plate 30 for receiving the sample liquid discharged by the suction and discharge assembly is also provided on the top of the movable plate 26, and a conveyor belt for driving the movable plate 26 to move on the second guide rail 27 is provided on the top of the base 1. Several unused suction tips 9 are placed on the pipe filling rack 28, and the movable plate 26 moves on the base 1 under the action of the conveyor belt, so that the pipe filling rack 28, the waste box 29 and the deep-well plate 30 placed above it are located directly below the suction tip 9 according to different working conditions. If the suction tip 9 needs to be replaced, the pipe filling rack 28 is aligned with the liquid suction and discharge head 19, and then the liquid suction and discharge head 19 is lowered and inserted into the suction tip 9 to complete the installation of the suction tip 9, thereby facilitating the replacement of the suction tip 9 and allowing the waste box 29 to receive the used suction tip 9 that has fallen off or allowing the deep-well plate 30 to receive the sample liquid discharged by the suction tip 9. The coordination between the various components greatly improves the efficiency of cupping the sample liquid.

[0025] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention and are not limiting. Although the present invention has been described in detail with reference to the preferred embodiments, those skilled in the art should understand that the technical solutions of the present invention may be modified or replaced by equivalents without departing from the purpose and scope of the technical solutions of the present invention, which should all be included in the scope of the claims of the present invention.

Claims

1. A sample cupping device, characterized in that: include: A base (1), wherein a mechanical clamp (2) for fixing a sample tube on the base (1) is provided on the top of the base (1), and a supporting platform (3) for placing the sampling tube is provided on one side of the mechanical clamp (2); A first guide rail (4) is mounted on the upper side of the base (1) via a mounting frame (5). A transfer manipulator (6) and a horizontal plate (7) are slidably provided on the first guide rail (4). The mounting frame (5) is further provided with a driving mechanism for driving the transfer manipulator (6) and the horizontal plate (7) to slide on the first guide rail (4). The transfer manipulator (6) is used to clamp the sampling tube and transport it to the mechanical gripper (2). Four vertical plates (8) are slidably provided on the side wall of the horizontal plate (7). The length direction of each vertical plate (8) is perpendicular to the length direction of the horizontal plate (7); a first driving assembly for driving the vertical plate (8) to slide on the horizontal plate (7) is provided on the side wall of the horizontal plate (7) away from the vertical plate (8); a liquid suction and discharge assembly for sucking or discharging the sample liquid in the sampling tube is slidably provided on the side wall of each vertical plate (8); a suction head (9) is detachably mounted on the liquid suction and discharge assembly; and a second driving assembly for driving the corresponding liquid suction and discharge assembly to move up and down is provided on each vertical plate (8); A pipe filling assembly, the pipe filling assembly being arranged on the top of the base (1), and supplying a suction head (9) to the liquid suction and discharge assembly; Each of the liquid suction and discharge components comprises: a mounting block (17) and a piston rod (18), wherein the mounting block (17) is fixedly connected to the connecting piece (31), a mounting cavity is provided inside the mounting block (17), one end of the piston rod (18) is slidably connected to the mounting cavity, a liquid suction and discharge head (19) is provided at the bottom of the mounting block (17), and the liquid suction and discharge head (19) is communicated with the mounting cavity, a third driving component for driving the piston rod (18) to rise or fall is also provided at the top of the mounting block (17), and a tube removal component for facilitating the removal of a used suction head (9) is also provided at the bottom of the mounting block (17); The third driving assembly comprises: a driving motor (20), the driving motor (20) being fixedly mounted on the side wall of the corresponding vertical plate (8), a screw rod (21) being provided on the output end of the driving motor (20), a push block (22) being sleeved on the screw rod (21), the side wall of the push block (22) being slidably connected to the side wall of the vertical plate (8), and the bottom of the push block (22) being fixedly connected to an end of the piston rod (18) located outside the mounting cavity; The tube removal assembly comprises: a push rod (23), one end of the push rod (23) passes through the mounting cavity from top to bottom and is provided with a push plate (24), a through hole is opened on the push plate (24), the push plate (24) is slidably connected to the liquid suction and discharge head (19) through the through hole, a return spring (25) is further provided between the push rod (23) and the mounting block (17), and the top end of the push rod (23) is located directly below the push block (22); The tube filling assembly comprises: a movable plate (26), the movable plate (26) being arranged on the top of the base (1) via a second guide rail (27), a tube filling rack (28) for placing a pipette tip (9) and a waste box (29) for placing discarded pipette tips (9) being provided on the top of the movable plate (26), a deep-well plate (30) for receiving sample liquid discharged by the liquid suction and discharge assembly being further provided on the top of the movable plate (26), and a conveyor belt for driving the movable plate (26) to move on the second guide rail (27) being provided on the top of the base (1).

2. The sample cupping processing device according to claim 1, characterized in that: The first driving component includes: a first synchronous wheel (10), the first synchronous wheels (10) are four, and the four first synchronous wheels (10) are symmetrically and rotatably arranged at both ends of the horizontal plate (7) in a group of two, and a first conveyor belt (11) is sleeved between every two first synchronous wheels (10) at the same horizontal height, and two clamping blocks (12) are fixedly provided on each of the first conveyor belts (11), two through slots are provided on the horizontal plate (7), and one end of each clamping block (12) extends out of the through slot and is fixedly connected to the vertical plate (8), and two first motors (13) are also provided on the side wall of the horizontal plate (7) to drive the corresponding first synchronous wheels (10) to rotate.

3. The sample cupping processing device according to claim 1, characterized in that: Each of the second drive components comprises: a second synchronous wheel (14), two second synchronous wheels (14) are rotatably arranged at both ends of each vertical plate (8), a second conveyor belt (15) is sleeved between the two second synchronous wheels (14), each second conveyor belt (15) is fixedly connected to a liquid suction and discharge component via a connecting member (31), and a second motor (16) is provided on the side wall of each vertical plate (8) for driving the corresponding second synchronous wheel (14) to rotate.

Images