A Tremella polysaccharide nanofiber composite facial mask and its preparation, use and application

Abstract

The invention discloses a tremella polysaccharide nanofiber composite facial mask and its preparation, use and application, belonging to the technical field of daily chemical facial masks. The tremella polysaccharide nanofiber composite facial mask is composed of functional components such as tremella polysaccharide and collagen and other beauty and skin care active ingredients, and a carrier component composed of natural high molecular polymers and gelatin, etc., and adopts a double-head parallel electrostatic spinning technology. The spinning solutions of each component are independently sprayed and then intertwined in parallel and then deposited to form a nanofiber composite facial mask. The facial mask has good biocompatibility, is made of natural high molecular materials, is environmentally friendly and degradable, has the characteristics of small fiber size, large specific surface area, excellent pore structure, etc., has extremely strong absorbency and permeability, is conducive to the diffusion and dissolution of active ingredients, and improves the ability of percutaneous absorption. The facial mask is a dry facial mask that can be stored for a long time without the use of preservatives. At the same time, it has good mechanical properties and integrity, which greatly enriches the application scenarios of the facial mask.

Description

Technical Field

[0001] The invention belongs to the technical field of daily chemical facial masks, and specifically relates to a tremella polysaccharide nanofiber composite facial mask and its preparation, use and application. Background Art

[0002] It is human nature to love beauty, and keeping the skin white, moisturized and barrier repaired is the key point. With the continuous improvement of people's living standards, people's requirements for their own skin are getting higher and higher. More people pay attention to facial skin care, and beauty masks are widely used in beauty cosmetics.

[0003] Facial masks are products that have cosmetic effects on the face and other skin. The principle is to apply a thick layer of dressings with different ingredients and functions on the face, so that the nutrients that penetrate into the skin can spread deeper and wider between cells, achieving a cosmetic skin care effect. Beauty masks are generally composed of mask liquid and mask cloth. The material of the mask cloth is usually blended cloth, chemical spun cloth, silk, cotton, polyester, bio-fiber, plant fiber, etc.; the mask liquid is matched with different nutritional raw materials according to different cosmetic skin care functions. When the mask is used, the active ingredients of the mask liquid are dissolved, usually within 10-20 minutes, to provide nutrients to the facial skin. After use, remove the mask, clean the face, and end the facial care operation.

[0004] At present, most conventional facial masks are wet masks composed of a mask nutrient solution and a mask base fabric. The mask nutrient solution is an immersion solution. Since the immersion solution contains nutrients and a large amount of water, long-term immersion is prone to produce microorganisms and bacteria, which directly affects the shelf life of the mask, especially the effective period of biological activity. In order for the mask nutrient solution to have a shelf life of 2 years, it is inevitable to use preservatives to achieve quality assurance, and preservatives are harmful to the skin and have the risk of allergies.

[0005] At present, the base fabrics of facial masks are usually made of blended fabrics, silk, cotton, polyester, bio-fiber, plant fiber, etc.; chemical-based fabrics have the lowest cost and are widely used, but they have skin allergies. At the same time, chemical-based fabrics are difficult to degrade, which has an impact on the environment; while natural fiber membrane fabrics are environmentally friendly and skin-friendly, but their fibers are relatively coarse and the relative surface area is not high, and the loading capacity of active ingredients is not high. They are only a carrier of the mask nutrient solution and cannot provide skin care active ingredients themselves, so the overall efficacy is average and the cost is relatively expensive.

[0006] The dry mask or electrospun nanofiber cloth (paper) currently used needs to be used with a skin care solution (essence or lotion, etc.) liquid. It is essentially a mask base cloth, and its efficacy is determined by the skin care solution. When using it, you also need to prepare the skin care solution and soaking container, which is very inconvenient.

[0007] The freeze-dried masks currently used all soak the essence system into the membrane fabric and perform a freeze-drying process, which avoids the damage to the skin caused by the use of preservatives; but in essence it is still a solid-liquid separation mask model, and does not improve the degradation problems, drug loading problems, transdermal absorption problems and biocompatibility problems. Summary of the invention

[0008] The first purpose of the present invention is to provide a Tremella polysaccharide nanofiber composite facial mask, which is a dry facial mask made of natural polymer materials. It uses an independent mode of active ingredients and carrier ingredients to exert their effectiveness, solving the technical problems of the existing technology such as the addition of preservatives in facial mask paper and facial mask liquid, difficulty in degradation, low drug loading, low percutaneous absorption and poor biocompatibility.

[0009] The second purpose of the present invention is to provide a method of utilizing Tremella fuciformis polysaccharide extract as an active ingredient raw material. Since the Tremella fuciformis polysaccharide extract has very high viscosity and surface tension, electrospinning is very difficult. By increasing the temperature of the Tremella fuciformis polysaccharide extract and the spinning needle, the surface tension of the spinning solution is reduced, thereby realizing the possibility of electrospinning. This solves the problem of using chemical solvents to reduce the surface tension of the spinning solution in existing electrospinning.

[0010] The third object of the present invention is to provide a method for spinning a facial mask using an electrospinning process. The polymer nanofibers prepared by the electrospinning method have the advantages of large specific surface area, high porosity, and light weight, and have potential application value in the fields of wound dressings, tissue engineering, and drug carriers. However, research on electrospinning in the field of facial masks is relatively rare.

[0011] The present invention is achieved through the following technical solutions:

[0012] A Tremella polysaccharide nanofiber composite facial mask, the composite facial mask comprising an effective component and a carrier component;

[0013] The efficacy component is composed of Tremella polysaccharide extract, collagen and sodium hyaluronate;

[0014] The carrier component is composed of natural high molecular polymer and gelatin;

[0015] The Tremella polysaccharide extract comprises any one of a Tremella polysaccharide stock solution, a Tremella superfine powder aqueous solution and a Tremella polysaccharide freeze-dried powder aqueous solution;

[0016] The natural high molecular polymer includes any one of chitosan, sodium alginate, sodium hyaluronate, collagen, alcohol-soluble protein and silk fibroin.

[0017] Preferably, the efficacy component comprises 10-20 parts of Tremella polysaccharide extract, 1-5 parts of collagen and 5-10 parts of sodium hyaluronate;

[0018] The carrier component contains 3-10 parts of natural high molecular polymer and 15-50 parts of gelatin.

[0019] A method for preparing a Tremella polysaccharide nanofiber composite facial mask comprises the following steps:

[0020] S1. Preparation of efficacy components: select Tremella polysaccharide extract according to corresponding mass fraction, heat it, add collagen and sodium hyaluronate, mix at constant temperature, obtain efficacy component solution, and keep it for later use;

[0021] S2. Preparation of carrier component: select natural high molecular polymer according to corresponding mass fraction, add it to the heated aqueous solution and mix it evenly, then add gelatin and mix it evenly to obtain carrier component solution, which is reserved for later use;

[0022] S3, high-voltage electrospinning: injecting the above-mentioned effective component solution and the carrier component solution into the spinning needles respectively, and placing the spinning needles of the above-mentioned component solutions in parallel for high-voltage electrospinning;

[0023] S4, mask collection: collecting the deposited nanofiber spinning membrane by using an electrospinning collector;

[0024] S5. Shaping and cutting: The collected nanofiber spinning membrane is picked, shaped, dried, and cut to obtain a facial mask.

[0025] During the preparation process of the composite mask, structural innovations were made: the mask structure of the composite nanofiber silk with two components in parallel, the functional component and the carrier component. The two components exert their effects independently: the double-head parallel electrospinning technology is adopted, and the spinning liquids of each component are independently sprayed, interwoven and entangled in parallel, and then deposited to form a nanofiber composite mask. The spinning of each component is relatively independent, and the parallel interweaving forms a nanofiber membrane, which has both independent skin care effects and an interwoven carrier structure. The independent carrier component nanofiber plays the role of a mask base fabric, has good biocompatibility, is environmentally friendly and degradable, has a high drug loading capacity, good toughness, and good mask integrity, forming an effective carrier support; the independent functional component nanofiber is made of Tremella polysaccharide plus a beauty and skin care formula, has a fast dissolution rate, and the active ingredients diffuse and dissolve quickly, providing beauty effects instantly. During the 10-20 minutes of using the mask, compared with the nanofiber membrane with mixed spinning solution, the active ingredients are released faster; compared with the liquid mask nutrient solution, the active ingredients are absorbed faster; compared with the natural cotton and silk mask cloth, the active ingredients have a larger loading capacity. The faster the active ingredients of the mask are released within a limited time, the more the face obtains, the more it is absorbed, and the better the beauty effect.

[0026] Preferably, in step S1, the heating temperature is 50-60°C;

[0027] The standby temperature of the efficacy component solution is 38-42°C.

[0028] Preferably, in step S2, the temperature of the heated solution is 50-60°C;

[0029] The standby temperature of the carrier component solution is 38-42°C.

[0030] Preferably, in step S3, the electrospinning environment is: voltage is 20-30KV, the distance from the needle to the receiver is 10-20cm, and the spinning solution propulsion speed is 10-20ul / s.

[0031] Preferably, the electrospinning environment temperature is 20-30°C, the spinning container and needle temperature are 50-60°C, and the environment humidity is 30-50% rh.

[0032] The above composite mask has innovations in the process of preparation: the spinning process of high-viscosity Tremella polysaccharide solution with double spinning needles and parallel temperature control: the temperature of the spinning container and the needle is controlled at 50-60℃: the higher the concentration of Tremella polysaccharide solution, the higher the viscosity, and the higher the surface tension, the more difficult the spinning, and the higher the spinning voltage; the surface tension of Tremella polysaccharide solution decreases with the increase of temperature; by increasing the temperature of the spinning solution and the needle, the surface tension is reduced, the jet is easily stimulated, and a better Taylor cone is formed, which improves the spinnability of the viscous solution, thereby avoiding the use of chemical solvents to reduce the surface tension. The process is more environmentally friendly and avoids the pollution of solvents to products and production environment.

[0033] A Tremella polysaccharide nanofiber composite facial mask is obtained by the preparation method.

[0034] A method for using a Tremella polysaccharide nanofiber composite facial mask comprises: firstly moistening the face with purified water or base water, then applying the facial mask to the face, spraying purified water or base water to allow full absorption, and removing the mask after 10-15 minutes; or firstly soaking the facial mask with purified water or base water to allow full absorption, quickly taking it out, applying it to the face, and removing it after 10-15 minutes.

[0035] Application of a Tremella polysaccharide nanofiber composite facial mask in beauty cosmetics and biopharmaceutical products.

[0036] The above-mentioned composite facial mask is a dry facial mask that does not require the use of preservatives and has a shelf life of more than 2 years in the form of vacuum sterile packaging.

[0037] Compared with the prior art, the present invention has at least the following technical effects:

[0038] (I) The present invention provides a preparation method and use of a Tremella polysaccharide nanofiber composite mask. The functional component composed of beauty and skin care active ingredients such as Tremella polysaccharide and collagen, and the carrier component composed of natural high molecular polymers (chitosan, etc.) and gelatin, etc., adopts double-head parallel electrostatic spinning technology, and the spinning solutions of each component are independently sprayed and then intertwined in parallel and then deposited to form a nanofiber composite mask. The spinning of each component is relatively independent, and the nanofiber membrane is formed by parallel interweaving, which has both independent skin care effects and an interwoven carrier structure. The Tremella polysaccharide nanofiber composite mask has good biocompatibility, is environmentally friendly and degradable, and has the characteristics of small fiber size, large specific surface area, and excellent pore structure. Therefore, it has extremely strong absorbency and permeability, is conducive to the diffusion and dissolution of active ingredients, and improves the ability of percutaneous absorption. At the same time, the Tremella polysaccharide nanofiber composite mask not only has good mechanical properties and integrity, but also can conveniently and flexibly adjust the composition and ratio of active ingredients, greatly improving the functionality and application scenarios of the nanofiber mask.

[0039] (ii) The mask has a strong ability to be absorbed through the skin and has good cosmetic effects: The effective components of the mask are water-soluble cosmetic ingredients such as Tremella polysaccharide and collagen, which dissolve quickly, are conducive to the rapid diffusion and dissolution of active ingredients, and improve the ability to be absorbed through the skin, thereby achieving more excellent skin care effects.

[0040] (III) The composite mask has a high drug loading capacity and has excellent mechanical properties and biocompatibility: The carrier component of the mask is made of natural high molecular polymer and gelatin, which has good water resistance, provides good mechanical properties, and maintains the physical integrity of the mask. The composite mask has the characteristics of small fiber size, uniform diameter distribution, large specific surface area, and excellent pore structure, so it has a high drug loading capacity, strong absorption, permeability and biocompatibility.

[0041] (IV) The composite facial mask is a dry facial mask that does not require the use of preservatives. In the form of vacuum sterile packaging, the shelf life can be more than 2 years, thus avoiding the risk of damage to human skin and allergies caused by the use of preservatives.

[0042] (5) The composite mask is made of natural polymer materials, which are eco-friendly and biodegradable, thus avoiding the impact of chemical raw materials on the environment. DETAILED DESCRIPTION

[0043] The embodiments of the present invention will be described in detail below in conjunction with examples. However, those skilled in the art will understand that the following examples are only used to illustrate the present invention and should not be construed as limiting the scope of the present invention. The specific conditions not specified in the examples are carried out according to conventional conditions or conditions recommended by the manufacturer. The reagents or instruments used without indicating the manufacturer are all conventional products that can be purchased commercially.

[0044] Embodiment 1:

[0045] A tremella polysaccharide nanofiber composite facial mask comprises: 10 grams of tremella polysaccharide stock solution, 1 gram of collagen and 5 grams of sodium hyaluronate in the efficacy components;

[0046] The carrier component contains 10 grams of natural high molecular polymer and 15 grams of gelatin.

[0047] Chitosan is selected as the natural high molecular polymer.

[0048] A method for preparing a Tremella polysaccharide nanofiber composite facial mask comprises the following steps:

[0049] S1. Preparation of functional components: Heat the Tremella polysaccharide stock solution to 60°C, add collagen and sodium hyaluronate, and place in a 60°C water bath and stir evenly to obtain a facial mask functional component solution; in order to prevent gel formation of the functional component solution, maintain the temperature of the functional component solution at 42°C.

[0050] S2. Preparation of carrier component: heat ionized water to 60°C, add acetic acid to adjust the pH value to 4.5-5 for a weakly acidic aqueous solution, then add chitosan, stir evenly to obtain a natural high molecular polymer solution; heat deionized water to 60°C, add gelatin, stir evenly to obtain a gelatin solution; mix the chitosan solution with the gelatin solution, place in a 60°C water bath and stir evenly to obtain a carrier component solution; in order to prevent gel formation of the carrier component solution, maintain the temperature of the carrier component solution at 42°C.

[0051] S3, high-voltage electrospinning: the functional component solution is poured into the spinning container A, the carrier component solution is poured into the spinning container B, the A\B spinning needles are arranged in parallel, and high-voltage electrospinning is performed; during the spinning process, the temperature of the spinning needle and the spinning container is maintained at 60°C.

[0052] S4, mask collection: collecting the deposited nanofiber spinning membrane through a spinning collector;

[0053] S5, shaping and cutting: taking the spun film, shaping, drying and cutting it into a facial mask;

[0054] The above electrospinning environment is: voltage 20-30KV, distance from needle to receiver 10-20cm, spinning solution advancement speed 10-20ul / s, ambient temperature 20-30°C, spinning container and needle temperature 60°C, ambient humidity 30-50%rh.

[0055] Embodiment 2:

[0056] A tremella polysaccharide nanofiber composite facial mask comprises: 20 grams of tremella polysaccharide stock solution, 5 grams of collagen and 10 grams of sodium hyaluronate in the efficacy components;

[0057] The carrier component contains 3 grams of natural high molecular polymer and 15 grams of gelatin.

[0058] Sodium alginate is selected as the natural high molecular polymer.

[0059] A method for preparing a Tremella polysaccharide nanofiber composite facial mask comprises the following steps:

[0060] S1. Preparation of functional components: Heat the Tremella polysaccharide stock solution to 50°C, add collagen and sodium hyaluronate, and place in a 50°C water bath and stir evenly to obtain a facial mask functional component solution; in order to prevent gel formation of the functional component solution, maintain the temperature of the functional component solution at 38°C.

[0061] S2. Preparation of carrier component: heat deionized water to 50°C, add sodium alginate, stir evenly to obtain a natural high molecular polymer solution; heat deionized water to 50°C, add gelatin, stir evenly to obtain a gelatin solution; mix the sodium alginate solution and the gelatin solution, place them in a 50°C water bath and stir evenly to obtain a carrier component solution; in order to prevent gel formation of the carrier component solution, maintain the temperature of the carrier component solution at 38°C.

[0062] S3, high-voltage electrospinning: the functional component solution is poured into the spinning container A, the carrier component solution is poured into the spinning container B, the A\B spinning needles are arranged in parallel, and high-voltage electrospinning is performed; during the spinning process, the temperature of the spinning needle and the spinning container is maintained at 50°C.

[0063] S4, mask collection: collecting the deposited nanofiber spinning membrane through a spinning collector;

[0064] S5, shaping and cutting: taking the spun film, shaping, drying and cutting it into a facial mask;

[0065] The above electrospinning environment is: voltage 20-30KV, distance from needle to receiver 10-20cm, needle diameter 0.3mm-0.8mm, spinning solution advancement speed 10-20ul / s, ambient temperature 20-30℃, spinning container and needle temperature 50℃, ambient humidity 30-50%rh.

[0066] Embodiment 3:

[0067] The natural high molecular polymer is sodium hyaluronate. The other parts are the same as in Example 2.

[0068] Embodiment 4:

[0069] The natural high molecular polymer is selected from collagen. The other parts are the same as in Example 2.

[0070] Embodiment 5:

[0071] The natural high molecular polymer is selected from prolamin. The other parts are the same as in Example 2.

[0072] Embodiment 6:

[0073] The natural high molecular polymer is selected from silk fibroin. The other parts are the same as those in Example 2.

[0074] Control Example 1: Refer to Example 2, but only use the functional component solution and single needle spinning technology to prepare the facial mask.

[0075] Control Example 2: Refer to Example 2, but only use the carrier component solution and single needle spinning technology to prepare the facial mask.

[0076] Control Example 3: Referring to Example 2, a facial mask was prepared by mixing the functional component solution and the carrier component solution and using single needle spinning technology.

[0077] Comparative Example 1: Refer to Example 2, but replace the Tremella polysaccharide stock solution in Example 2 with Tremella superfine powder aqueous solution, and the other process steps remain unchanged.

[0078] Comparative Example 2: Refer to Example 2, but replace the Tremella polysaccharide stock solution in Example 2 with Tremella polysaccharide freeze-dried powder aqueous solution, and the other process steps remain unchanged.

[0079] Experimental indicators: Testing and comparative evaluation of three aspects of performance, including dissolution and diffusion of active ingredients, integrity of the mask, and experience during use.

[0080] The above three control examples, two comparative examples and Example 2 were selected as experimental objects.

[0081] Experiment 1:

[0082] Dissolution and diffusion test: Test the dissolution and diffusion performance indicators of active ingredients such as Tremella polysaccharide in the mask.

[0083] Experimental process:

[0084] Take 10 grams of the finished products prepared by the above experimental objects, put them into a 500ml water container to absorb water, take out the mask after soaking for the following set time, and test the viscosity of the aqueous solution in the water container after dissolution and diffusion:

[0085] Infiltration time 30 seconds 1 minute 5 minutes 15 minutes 30 minutes Dissolution Diffusion Test mPa.s mPa.s mPa.s mPa.s mPa.s Example 2 4.09 15.26 17.61 18.75 19.50 Comparative Example 1 8.35 23.54 30.76 33.86 37.17 Comparative Example 2 1.17 1.58 1.67 1.70 1.73 Comparative Example 3 2.42 7.63 8.49 9.12 9.74

[0086] The above results show that, compared with Control Example 1 and Control Example 2, the independent functional component has good dissolution and diffusion properties; Control Example 3 shows that if the two components are mixed and spun, the dissolution and diffusion properties will be affected; Example 2 shows that if the two components are spun independently and in parallel, the dissolution and diffusion properties are basically unaffected.

[0087] Experiment 2:

[0088] Integrity test: Mask integrity indicators including tensile fracture mechanical properties and water resistance in dry state and in-use state (water absorption and infiltration).

[0089] Take 10cm×10cm of the finished products prepared by the above experimental objects, put them into a water container to absorb water, take out the mask after soaking for the following set time, and test the tensile fracture mechanical properties of the mask: (the mask is generally used for 10-20 minutes).

[0090]

[0091]

[0092] The above results show that in Example 2, Control Example 2, Control Example 3, and Comparative Examples 1 and 2, with the support of the carrier component, the mechanical properties and water resistance of the mask can be greatly improved, whether it is independent spinning or mixed spinning. However, Control Example 1 only has the functional component, and it is difficult to achieve the integrity of the mask.

[0093] Experiment 3: Experience test: 30 people were organized to evaluate the comprehensive experience indicators, including five indicators that affect the user experience: mask appearance, facial fit, comfort during use, cleaning after use, and skin care effect after use.

[0094] 30 samples of the finished products were taken and evaluated by 30 volunteers, and a five-level evaluation was conducted based on the users' experience.

[0095]

[0096]

[0097] Evaluation test form:

[0098]

[0099]

[0100] Test evaluation: After using the control example 1, the mask was severely damaged and the experience was very poor; the mask of the control example 2 had good integrity, but did not have much beauty effect; the beauty effects of the control example 3 and the comparative example 1 were also average; the overall experience and effect of the embodiment 2 and the comparative example 2 were the best.

[0101] Finally, it should be noted that the above description is only a preferred embodiment of the present invention and is not intended to limit the protection scope of the present invention. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included in the protection scope of the present invention.

Claims

1. A Tremella polysaccharide nanofiber composite facial mask, characterized in that: The composite facial mask comprises an efficacy component and a carrier component; The efficacy component is composed of Tremella polysaccharide extract, collagen and sodium hyaluronate; The carrier component is composed of natural high molecular polymer and gelatin; The Tremella polysaccharide extract comprises any one of a Tremella polysaccharide stock solution, a Tremella superfine powder aqueous solution and a Tremella polysaccharide freeze-dried powder aqueous solution; The natural high molecular polymer includes any one of chitosan, sodium alginate, sodium hyaluronate, collagen, alcohol-soluble protein and silk fibroin; The efficacy components include 10-20 parts of Tremella polysaccharide extract, 1-5 parts of collagen and 5-10 parts of sodium hyaluronate; The carrier component comprises 3-10 parts of natural high molecular polymer and 15-50 parts of gelatin; The preparation method of the Tremella polysaccharide nanofiber composite facial mask comprises the following steps: S1. Preparation of efficacy components: select Tremella polysaccharide extract according to corresponding mass fraction, heat it, add collagen and sodium hyaluronate, mix at constant temperature, obtain efficacy component solution, and keep it for later use; S2. Preparation of carrier component: select natural high molecular polymer according to corresponding mass fraction, add it to the heated aqueous solution and mix it evenly, then add gelatin and mix it evenly to obtain carrier component solution, which is reserved for later use; S3, high-voltage electrospinning: the above-mentioned functional component solution is poured into the spinning container A, the carrier component solution is poured into the spinning container B, and the A\B spinning needles are arranged in parallel to perform high-voltage electrospinning; the high-voltage electrospinning environment is: the voltage is 20-30KV, the needle diameter is 0.3mm-0.8mm, the distance from the needle to the receiver is 10-20cm, and the spinning solution propulsion speed is 10-20μl / s; S4, mask collection: collecting the deposited nanofiber spinning membrane by using an electrospinning collector; S5. Shaping and cutting: The collected nanofiber spinning membrane is picked, shaped, dried, and cut to obtain a facial mask.

2. A Tremella polysaccharide nanofiber composite facial mask according to claim 1, characterized in that: In step S1, the heating temperature is 50-60°C; The standby temperature of the effective component solution is 38-42°C.

3. A Tremella polysaccharide nanofiber composite facial mask according to claim 1, characterized in that: In step S2, the temperature of the heated aqueous solution is 50-60°C; The standby temperature of the carrier component solution is 38-42°C.

4. A Tremella polysaccharide nanofiber composite facial mask according to claim 1, characterized in that: The environment temperature of the high-voltage electrospinning is 20-30° C., the temperature of the spinning container and the needle is 50-60° C., and the environment humidity is 30-50% rh.

5. A non-therapeutic method of using the Tremella polysaccharide nanofiber composite facial mask as claimed in any one of claims 1 to 4, characterized in that: include: First moisten your face with purified water or base water, then apply the mask to the face and spray purified water or base water to allow full absorption, and remove it after 10-15 minutes; or first moisten the mask with purified water or base water to allow full absorption, quickly take it out, apply it to the face, and remove it after 10-15 minutes.

6. Use of the Tremella polysaccharide nanofiber composite facial mask as described in any one of claims 1 to 4 in the preparation of beauty cosmetics.

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